Compounds > ro 31-8220
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ro 31-8220 and thromboxane a2

ro 31-8220 has been researched along with thromboxane a2 in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asselin, J; Blake, RA; Walker, T; Watson, SP1
Jin, J; Kunapuli, SP; Paul, BZ1
Akkerman, JW; Gorter, G; van Willigen, G1
Atkinson, BT; Pears, CJ; Stafford, MJ; Watson, SP1
Dangelmaier, C; Daniel, JL; Dorsam, RT; Jin, J; Kim, S; Kunapuli, SP; Quinton, TM1
Jho, EH; Kim, JM; Kim, S; Kim, SY; Oh, D; Park, S; Yun-Choi, HS1

Other Studies

6 other study(ies) available for ro 31-8220 and thromboxane a2

ArticleYear
Fc gamma receptor II stimulated formation of inositol phosphates in human platelets is blocked by tyrosine kinase inhibitors and associated with tyrosine phosphorylation of the receptor.
    FEBS letters, 1994, Mar-28, Volume: 342, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Blood Platelets; Egtazic Acid; Humans; Indoles; Inositol Phosphates; Phosphorylation; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, IgG; Staurosporine; Styrenes; Thrombin; Thromboxane A2; Type C Phospholipases; Tyrosine

1994
Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors.
    The Journal of biological chemistry, 1999, Oct-08, Volume: 274, Issue:41

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Calcium; Cell Size; GTP-Binding Proteins; Humans; Indoles; Membrane Proteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Signal Transduction; Thromboxane A2; Vasoconstrictor Agents; Yohimbine

1999
Thrombopoietin increases platelet sensitivity to alpha-thrombin via activation of the ERK2-cPLA2 pathway.
    Thrombosis and haemostasis, 2000, Volume: 83, Issue:4

    Topics: Animals; Blood Platelets; Carbazoles; Cattle; Cytoplasmic Granules; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Group IV Phospholipases A2; Humans; Imidazoles; Indoles; Indomethacin; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Aggregation; Protein Kinase C; Protein Processing, Post-Translational; Pyridines; Serotonin; Serum Albumin, Bovine; Thrombin; Thrombopoietin; Thromboxane A2

2000
Signalling events underlying platelet aggregation induced by the glycoprotein VI agonist convulxin.
    European journal of biochemistry, 2001, Volume: 268, Issue:20

    Topics: Adenosine Diphosphate; Animals; Apyrase; CD36 Antigens; Crotalid Venoms; Drug Synergism; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Indoles; Indomethacin; Lectins, C-Type; Mice; Phosphatidic Acids; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Serotonin; Signal Transduction; Thromboxane A2

2001
Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation.
    The Biochemical journal, 2002, Dec-01, Volume: 368, Issue:Pt 2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Blood Platelets; Calcium; Cells, Cultured; Dual Specificity Phosphatase 2; Egtazic Acid; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Indoles; Integrin alpha1beta1; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Receptors, Fibrinogen; Signal Transduction; Thromboxane A2

2002
PKC inhibitors RO 31-8220 and Gö 6983 enhance epinephrine-induced platelet aggregation in catecholamine hypo-responsive platelets by enhancing Akt phosphorylation.
    BMB reports, 2011, Volume: 44, Issue:2

    Topics: Adult; Androstadienes; Carbazoles; Catecholamines; Epinephrine; Female; Humans; Indoles; Male; Maleimides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Aggregation; Protein Kinase C; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Thromboxane A2; Wortmannin

2011