Page last updated: 2024-08-16

ro 31-8220 and sirolimus

ro 31-8220 has been researched along with sirolimus in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (33.33)18.2507
2000's8 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caivano, M; Cohen, P; Davies, SP; Reddy, H1
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H1
Backwell, FR; Mackie, SC; Morrison, KS; Palmer, RM; Pascal, M; Thom, A; Thompson, MG1
Fraser, C; Morley, S1
Beale, G; Mallon, B; Morreale, A; Rumsby, M; Watson, J1
Bae, GU; Ha, KS; Han, JW; Hong, S; Kwon, HK; Lee, HW; Lee, HY; Lee, ZW; Seo, DW1
Alessi, DR; Cuenda, A1
Beale, G; Cross, J; England, K; Rumsby, M; Warner, M; Watson, J1
Hannan, KM; Marmy-Conus, N; Pearson, RB1
Acitores, A; González, N; Sancho, V; Valverde, I; Villanueva-Peñacarrillo, ML2

Reviews

1 review(s) available for ro 31-8220 and sirolimus

ArticleYear
Use of kinase inhibitors to dissect signaling pathways.
    Methods in molecular biology (Clifton, N.J.), 2000, Volume: 99

    Topics: Androstadienes; Animals; Chromones; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Maleimides; Morpholines; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Sirolimus; Wortmannin

2000

Other Studies

11 other study(ies) available for ro 31-8220 and sirolimus

ArticleYear
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
    The Biochemical journal, 2000, Oct-01, Volume: 351, Issue:Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Amides; Animals; Benzamides; Benzophenanthridines; Benzopyrans; Butadienes; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Isoquinolines; Lithium; Magnesium; Nitriles; Phenanthridines; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Sirolimus; Substrate Specificity; Sulfonamides

2000
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-27, Volume: 104, Issue:48

    Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers

2007
Evidence that protein kinase C and mitogen activated protein kinase are not involved in the mechanism by which insulin stimulates translation in L6 myoblasts.
    Bioscience reports, 1995, Volume: 15, Issue:1

    Topics: Amino Acid Sequence; Animals; Antifungal Agents; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cyclooxygenase Inhibitors; Dactinomycin; Down-Regulation; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Ibuprofen; Indoles; Insulin; Molecular Sequence Data; Muscle Fibers, Skeletal; Polyenes; Protein Biosynthesis; Protein Kinase C; Sirolimus; Tetradecanoylphorbol Acetate

1995
Studies on the phosphorylation of eIF4E in Xenopus (XIK-2) kidney cells.
    Biochemical Society transactions, 1997, Volume: 25, Issue:2

    Topics: Animals; Cell Line; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Flavonoids; Hot Temperature; Immunosuppressive Agents; Indoles; Kidney; Kinetics; Peptide Initiation Factors; Phosphorylation; Polyenes; Protein Kinase C; Sirolimus; Tetradecanoylphorbol Acetate; Xenopus

1997
Ro31-8220 inhibits protein kinase C to block the phorbol ester-stimulated release of choline- and ethanolamine-metabolites from C6 glioma cells: p70 S6 kinase and MAPKAP kinase-1beta do not function downstream of PKC in activating PLD.
    FEBS letters, 1997, Nov-03, Volume: 417, Issue:1

    Topics: Androstadienes; Animals; Choline; Enzyme Inhibitors; Ethanolamine; Flavonoids; Glioma; Indoles; Phosphoinositide-3 Kinase Inhibitors; Phospholipase D; Polyenes; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Sirolimus; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Wortmannin

1997
Hydrogen peroxide activates p70(S6k) signaling pathway.
    The Journal of biological chemistry, 1999, Nov-12, Volume: 274, Issue:46

    Topics: Androstadienes; Animals; Calcium; Catalase; Cell Line; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Hydrogen Peroxide; Indoles; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Reactive Oxygen Species; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; Wortmannin

1999
Signalling pathways regulating the dephosphorylation of Ser729 in the hydrophobic domain of protein kinase Cepsilon upon cell passage.
    The Journal of biological chemistry, 2001, Mar-30, Volume: 276, Issue:13

    Topics: 3T3 Cells; Alkaloids; Animals; Anti-Bacterial Agents; Benzophenanthridines; Blotting, Western; Calcineurin; Cell Adhesion; Cell Line; Culture Media; Cyclosporine; Down-Regulation; Enzyme Inhibitors; Flavonoids; Indoles; Isoenzymes; MAP Kinase Signaling System; Marine Toxins; Methionine; Mice; Models, Biological; Okadaic Acid; Oxazoles; Phenanthridines; Phosphoprotein Phosphatases; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-epsilon; Protein Structure, Tertiary; Serine; Signal Transduction; Sirolimus; Tacrolimus; Transfection

2001
Ro 31-6045, the inactive analogue of the protein kinase C inhibitor Ro 31-8220, blocks in vivo activation of p70(s6k)/p85(s6k): implications for the analysis of S6K signalling.
    FEBS letters, 2002, May-22, Volume: 519, Issue:1-3

    Topics: Animals; Cell Line; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Humans; Indoles; Isoquinolines; Kidney; Maleimides; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Structure-Activity Relationship; Sulfonamides; TOR Serine-Threonine Kinases; Transfection

2002
Cell signalling of glucagon-like peptide-1 action in rat skeletal muscle.
    The Journal of endocrinology, 2004, Volume: 180, Issue:3

    Topics: Androstadienes; Animals; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glucagon; Glucagon-Like Peptide 1; Glycogen Synthase; In Vitro Techniques; Indoles; Insulin; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Okadaic Acid; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Precursors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Tumor Necrosis Factor-alpha; Wortmannin

2004
Effect of GLP-1 on glucose transport and its cell signalling in human myocytes.
    Regulatory peptides, 2005, Mar-30, Volume: 126, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aged; Aged, 80 and over; Androstadienes; Biological Transport; Cells, Cultured; Enzyme Activation; Exenatide; Female; Flavonoids; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Indoles; Insulin; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle Cells; Peptide Fragments; Peptides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Precursors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Venoms; Wortmannin

2005