Page last updated: 2024-08-16

ro 31-8220 and ruboxistaurin

ro 31-8220 has been researched along with ruboxistaurin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Bach, S; Cahill, MM; Marchand, P; McCarthy, FO; O'Shea, KD; Pierce, LT; Robert, T; Ruchaud, S; Winfield, HJ1
Goekjian, PG; Jirousek, MR1
Hori, M; Kanzaki, H; Nakajima, T; Nakamoto, T; Okada, H; Ozaki, H; Yasuda, K; Yasuhara, M1
Bohlen, HG; Borbouse, L; Dincer, UD; Payne, GA; Tune, JD1
Correll, RN; Hajjar, RJ; Houser, SR; Ishikawa, K; Kawase, Y; Ladage, D; Molkentin, JD; Tilemann, L1
Bruyere, A; Denizot, C; Fardel, O; Jouan, E; Mayati, A; Moreau, A; Parmentier, Y1

Reviews

1 review(s) available for ro 31-8220 and ruboxistaurin

ArticleYear
Protein kinase C in the treatment of disease: signal transduction pathways, inhibitors, and agents in development.
    Current medicinal chemistry, 1999, Volume: 6, Issue:9

    Topics: Azepines; Bryostatins; Carbazoles; Enzyme Inhibitors; Humans; Hydroxybenzoates; Indoles; Lactones; Macrolides; Maleimides; Oligodeoxyribonucleotides, Antisense; Protein Kinase C; Pyrroles; Signal Transduction; Thionucleotides

1999

Other Studies

6 other study(ies) available for ro 31-8220 and ruboxistaurin

ArticleYear
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
Synthesis and anticancer activity of novel bisindolylhydroxymaleimide derivatives with potent GSK-3 kinase inhibition.
    Bioorganic & medicinal chemistry, 2018, 08-07, Volume: 26, Issue:14

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glycogen Synthase Kinase 3; Humans; Maleimides; Molecular Structure; Protein Kinase Inhibitors; Structure-Activity Relationship

2018
Role of protein kinase Cbeta in rhythmic contractions of human pregnant myometrium.
    Reproduction (Cambridge, England), 2007, Volume: 133, Issue:4

    Topics: Adult; Carbazoles; Case-Control Studies; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Indoles; Labor, Obstetric; Maleimides; Myometrium; Obstetric Labor, Premature; Oxytocics; Oxytocin; Pregnancy; Pregnancy Trimester, Third; Protein Kinase C; Protein Kinase C beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stimulation, Chemical; Uterine Contraction

2007
Periadventitial adipose tissue impairs coronary endothelial function via PKC-beta-dependent phosphorylation of nitric oxide synthase.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:1

    Topics: Adipose Tissue; Animals; Blotting, Western; Bradykinin; Coronary Vessels; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Indoles; Maleimides; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type III; Pericardium; Phosphorylation; Protein Kinase C; Protein Kinase C beta

2009
Inhibition of PKCα/β with ruboxistaurin antagonizes heart failure in pigs after myocardial infarction injury.
    Circulation research, 2011, Dec-09, Volume: 109, Issue:12

    Topics: Animals; Cardiac Output; Coronary Occlusion; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Heart; Heart Failure; Indoles; Maleimides; Myocardial Contraction; Myocardial Infarction; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Pyrroles; Stroke Volume; Swine

2011
Protein Kinase C-Independent Inhibition of Organic Cation Transporter 1 Activity by the Bisindolylmaleimide Ro 31-8220.
    PloS one, 2015, Volume: 10, Issue:12

    Topics: Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Green Fluorescent Proteins; HEK293 Cells; Humans; Indoles; Maleimides; Microscopy, Confocal; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Protein Kinase C; Tetraethylammonium

2015