Page last updated: 2024-08-16

ro 31-8220 and rottlerin

ro 31-8220 has been researched along with rottlerin in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (85.71)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caivano, M; Cohen, P; Davies, SP; Reddy, H1
McGovern, SL; Shoichet, BK1
Goekjian, P; Jochum, A; Jung, M; Kunick, C; Marshall, B; Meier, R; Saunders, L; Sippl, W; Trapp, J; Verdin, E1
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Lin, WW; Wen, HC1
Chen, JS; Song, JG1
Cho, W; Han, JM; Jung, YW; Kim, JH; Kim, Y; Kuroki, T; Lee, BD; Lee, S; Lee, SD; Ohba, M; Ryu, SH; Suh, PG1
Cui, MZ; Ogawa, W; Ohba, M; Tan, M; Xu, X1
Anel, A; Boyer, C; Buferne, M; Martínez-Lorenzo, MJ; Naval, J; Pardo, J; Schmitt-Verhulst, AM1
Bahraoui, E; Bennasser, Y; Contreras, X1
Li, F; Shi, J; Song, J; Wang, D; Zhou, Y1
Grybko, MJ; Pores-Fernando, AT; Wurth, GA; Zweifach, A1
Barthwal, MK; Bogra, J; Dikshit, M; Kohli, M; Kothari, N; Rana, M; Singh, A; Singh, V; Tiwari, RL; Verma, A1
Aschner, M; Bai, Y; Cai, J; Feng, Y; Jiang, Y; Li, F; Lu, R; Qian, H; Wang, Q; Wang, S; Xing, G; Yang, B; Yin, C; Zhang, Y; Zhou, Y1

Other Studies

14 other study(ies) available for ro 31-8220 and rottlerin

ArticleYear
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
    The Biochemical journal, 2000, Oct-01, Volume: 351, Issue:Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Amides; Animals; Benzamides; Benzophenanthridines; Benzopyrans; Butadienes; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Isoquinolines; Lithium; Magnesium; Nitriles; Phenanthridines; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Sirolimus; Substrate Specificity; Sulfonamides

2000
Kinase inhibitors: not just for kinases anymore.
    Journal of medicinal chemistry, 2003, Apr-10, Volume: 46, Issue:8

    Topics: beta-Lactamase Inhibitors; beta-Lactamases; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Biological; Phosphotransferases; Scattering, Radiation

2003
Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition.
    Journal of medicinal chemistry, 2006, Dec-14, Volume: 49, Issue:25

    Topics: Acetylation; Adenosine; Binding Sites; Cell Line, Tumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Models, Molecular; Molecular Mimicry; Protein Kinase Inhibitors; Sirtuins; Structure-Activity Relationship; Tubulin

2006
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
Basal cPLA(2) phosphorylation is sufficient for Ca(2+)-induced full activation of cPLA(2) in A549 epithelial cells.
    Journal of cellular biochemistry, 2000, Sep-14, Volume: 79, Issue:4

    Topics: Acetophenones; Arachidonic Acid; Benzopyrans; Calcium; Cell Line; Cytosol; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin

2000
Bradykinin induces protein kinase C-dependent activation of phospholipase D in A-431 cells.
    IUBMB life, 2001, Volume: 51, Issue:1

    Topics: Acetophenones; Benzopyrans; Bradykinin; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Immunoblotting; Indoles; Isoenzymes; Kinetics; Maleimides; Phospholipase D; Phospholipids; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2001
Phosphorylation-dependent regulation of phospholipase D2 by protein kinase C delta in rat Pheochromocytoma PC12 cells.
    The Journal of biological chemistry, 2002, Mar-08, Volume: 277, Issue:10

    Topics: Acetophenones; Adenoviridae; Animals; Benzopyrans; Bradykinin; Cell Membrane; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunoblotting; Immunohistochemistry; Indoles; Isoenzymes; Maleimides; Microscopy, Fluorescence; Mutation; PC12 Cells; Peptide Mapping; Phospholipase D; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Kinase C-delta; Protein Transport; Rats; Tetradecanoylphorbol Acetate; Time Factors; Up-Regulation

2002
Thrombin rapidly induces protein kinase D phosphorylation, and protein kinase C delta mediates the activation.
    The Journal of biological chemistry, 2003, Jan-31, Volume: 278, Issue:5

    Topics: Acetophenones; Animals; Aorta; Benzopyrans; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Imidazoles; Indoles; Kinetics; Maleimides; Muscle, Smooth, Vascular; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Pyridines; Rats; Thrombin

2003
Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression.
    International immunology, 2003, Volume: 15, Issue:12

    Topics: Acetophenones; Androstadienes; Animals; Antibodies, Monoclonal; Benzopyrans; Carbazoles; Cell Degranulation; Cell Line; Chromones; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; Fas Ligand Protein; Humans; Indoles; Ionomycin; Isoenzymes; Jurkat Cells; Luciferases; Lymphocyte Activation; Membrane Glycoproteins; Mice; Morpholines; Perforin; Phorbol Esters; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pore Forming Cytotoxic Proteins; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Kinase C-theta; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes, Cytotoxic; Transfection; Wortmannin

2003
IL-10 production induced by HIV-1 Tat stimulation of human monocytes is dependent on the activation of PKC beta(II) and delta isozymes.
    Microbes and infection, 2004, Volume: 6, Issue:13

    Topics: Acetophenones; Benzopyrans; Carbazoles; Cells, Cultured; Enzyme Inhibitors; Gene Expression Regulation; Gene Products, tat; HIV-1; Humans; Indoles; Interleukin-10; Maleimides; Monocytes; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-delta; Pyrones; tat Gene Products, Human Immunodeficiency Virus

2004
Different roles of protein kinase C-betaI and -delta in the regulation of adipocyte differentiation.
    The international journal of biochemistry & cell biology, 2006, Volume: 38, Issue:12

    Topics: 3T3-L1 Cells; Acetophenones; Adipocytes; Adipogenesis; Animals; Benzopyrans; Carbazoles; Cell Differentiation; Cell Membrane; Cell Proliferation; Chromans; Cytosol; Epidermal Growth Factor; Gene Expression; Genes, Dominant; Indoles; Mice; Mutant Proteins; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-delta; Protein Transport; Tetradecanoylphorbol Acetate; Thiazolidinediones; Transforming Growth Factor beta; Troglitazone

2006
Protein kinase C activity is required for cytotoxic T cell lytic granule exocytosis, but the theta isoform does not play a preferential role.
    Journal of leukocyte biology, 2007, Volume: 81, Issue:2

    Topics: Acetophenones; Benzopyrans; Calcium; Carbazoles; Cell Line, Tumor; Cell Membrane; Cytotoxicity, Immunologic; Exocytosis; Humans; Indoles; Mutation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase Inhibitors; Structure-Activity Relationship; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate

2007
PKCδ-IRAK1 axis regulates oxidized LDL-induced IL-1β production in monocytes.
    Journal of lipid research, 2014, Volume: 55, Issue:7

    Topics: Acetophenones; Acetylcysteine; Adult; Benzofurans; Benzopyrans; Carbazoles; Female; Humans; Indoles; Interleukin-1 Receptor-Associated Kinases; Interleukin-1beta; Lipoproteins, LDL; Male; Middle Aged; Monocytes; Onium Compounds; Protein Kinase C-delta; Reactive Oxygen Species; Systemic Inflammatory Response Syndrome; THP-1 Cells; Toll-Like Receptors

2014
Curcumin protects against methylmercury-induced cytotoxicity in primary rat astrocytes by activating the Nrf2/ARE pathway independently of PKCδ.
    Toxicology, 2019, 09-01, Volume: 425

    Topics: Acetophenones; Animals; Antioxidant Response Elements; Astrocytes; Benzopyrans; Curcumin; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Glutathione; Hylobatidae; Indoles; L-Lactate Dehydrogenase; Methylmercury Compounds; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Protein Kinase C-delta; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction

2019