ro 31-8220 has been researched along with genistein in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (56.00) | 18.2507 |
| 2000's | 8 (32.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bullock, AN; Debreczeni, JE; Fedorov, OY; Knapp, S; Marsden, BD; Nelson, A | 1 |
| Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR | 1 |
| Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR | 1 |
| Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR | 1 |
| Finney, M; Gordon, J; Katira, A; Knox, KA; Michell, RH; Wakelam, M | 1 |
| Briscoe, CP; Cross, M; Martin, A; Wakelam, MJ | 1 |
| Graham, A; Russell, LJ | 1 |
| Farndale, RW; Sage, SO; Sargeant, P | 1 |
| Blanco, A; Habib, A; Levy-Toledano, S; Maclouf, J | 1 |
| Farndale, RW; Hargreaves, PG; Jenner, S; Merritt, JE; Sage, SO | 1 |
| Burke-Gaffney, A; Hellewell, PG | 1 |
| Ahmed, A; Dearn, SR; Morrison, JJ; Smith, SK | 1 |
| Chopra, LC; Hucks, D; Twort, CH; Ward, JP | 1 |
| Abdel-Latif, AA; Husain, S | 1 |
| Breitbart, H; Luria, A; Rubinstein, S; Sun, QY | 1 |
| Aldershvile, J; Bauersachs, J; Busse, R; Fleming, I; Schäfer, A; Scholz, D | 1 |
| Klein, J; Kötter, K | 1 |
| Henrion, D; Lehoux, S; Lévy, BI; Loufrani, L; Tedgui, A | 1 |
| Befus, AD; Gilchrist, M; Grill, BJ; Hirji, N; Lin, TJ; Schreiber, AD; Stenton, GR | 1 |
| Araki, Y; Sendo, F; Yu, Y | 1 |
| Dickenson, JM; Germack, R | 1 |
| Creuzet, C; Dupouy-Camet, J; Robert-Gangneux, F; Roisin, MP | 1 |
| Corcos, L; Galisteo, M; Guillouzo, A; Joannard, F; Lagadic-Gossmann, D | 1 |
| Han, C; Lei, B; Zhang, Y | 1 |
| Dai, J; Remick, DG; Wang, X; Zeng, X | 1 |
25 other study(ies) available for ro 31-8220 and genistein
| Article | Year |
|---|---|
Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase.
Topics: Antineoplastic Agents; Crystallization; Crystallography, X-Ray; Flavonoids; Humans; Imidazoles; Indoles; Maleimides; Models, Molecular; Molecular Structure; Moloney murine leukemia virus; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-pim-1; Proviruses; Pyrazoles; Pyridazines; Pyrimidines; Structure-Activity Relationship | 2005 |
Highly predictive and interpretable models for PAMPA permeability.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine | 2017 |
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility | 2019 |
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States | 2020 |
Inhibition by glucocorticoid and staurosporine of IL-4-dependent CD23 production in B lymphocytes is reversed on engaging CD40.
Topics: Alkaloids; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; CD40 Antigens; Cells, Cultured; Genistein; Humans; In Vitro Techniques; Indoles; Interleukin-4; Isoflavones; Prednisolone; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, IgE; Recombinant Proteins; Signal Transduction; Staurosporine | 1993 |
The roles of multiple pathways in regulating bombesin-stimulated phospholipase D activity in Swiss 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Bombesin; Genistein; Glycerophospholipids; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Indoles; Isoflavones; Kinetics; Mice; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate; Vanadates | 1995 |
Stimulation of low-density lipoprotein uptake in HepG2 cells by epidermal growth factor via a tyrosine kinase-dependent, but protein kinase C-independent, mechanism.
Topics: Acetates; Cholesterol; Enzyme Activation; Epidermal Growth Factor; Esterification; Genistein; Humans; Indoles; Isoflavones; Lipoproteins, LDL; Protein Kinase C; Protein-Tyrosine Kinases; Sucrose; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
The tyrosine kinase inhibitors methyl 2,5-dihydroxycinnamate and genistein reduce thrombin-evoked tyrosine phosphorylation and Ca2+ entry in human platelets.
Topics: Biological Transport; Blood Platelets; Blotting, Western; Calcium; Cells, Cultured; Cinnamates; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Genistein; Humans; Indoles; Isoflavones; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Thrombin; Tyrosine | 1993 |
Involvement of tyrosine kinases in the induction of cyclo-oxygenase-2 in human endothelial cells.
Topics: Benzoquinones; Blotting, Western; Catechols; Cells, Cultured; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Genistein; Humans; Indoles; Interleukin-1; Isoenzymes; Isoflavones; Kinetics; Lactams, Macrocyclic; Nitriles; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Recombinant Proteins; Rifabutin; Tyrphostins; Umbilical Veins | 1995 |
Ionomycin-stimulated arachidonic acid release in human platelets: a role for protein kinase C and tyrosine phosphorylation.
Topics: Arachidonic Acid; Blood Platelets; Calcium; Collagen; Enzyme Inhibitors; Genistein; Humans; Indoles; Ionomycin; Ionophores; Isoflavones; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1996 |
Tumour necrosis factor-alpha-induced ICAM-1 expression in human vascular endothelial and lung epithelial cells: modulation by tyrosine kinase inhibitors.
Topics: Cell Adhesion; Cells, Cultured; Cinnamates; Endothelium, Vascular; Epithelium; Genistein; Humans; Indoles; Intercellular Adhesion Molecule-1; Isoflavones; Lung; Protein-Tyrosine Kinases; Sulfides; Tumor Necrosis Factor-alpha | 1996 |
Activation of protein kinase C is required for oxytocin-induced contractility in human pregnant myometrium.
Topics: Adult; Enzyme Activation; Enzyme Inhibitors; Female; Genistein; Humans; In Vitro Techniques; Indoles; Isoflavones; Myometrium; Oxytocin; Phospholipase D; Pregnancy; Protein Kinase C; Protein-Tyrosine Kinases; Staurosporine; Uterine Contraction | 1996 |
Effects of protein tyrosine kinase inhibitors on contractility of isolated bronchioles of the rat.
Topics: Acetylcholine; Animals; Bronchi; Caffeic Acids; Carbachol; Cinnamates; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; In Vitro Techniques; Indoles; Ionomycin; Isoflavones; Male; Muscle Contraction; Muscle, Smooth; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Serotonin; Sulfides; Tyrphostins | 1997 |
Role of protein kinase C alpha in endothelin-1 stimulation of cytosolic phospholipase A2 and arachidonic acid release in cultured cat iris sphincter smooth muscle cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cats; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Endothelin-1; Genistein; Indoles; Iris; Isoenzymes; Lipoprotein Lipase; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Kinase C-alpha | 1998 |
Protein kinase inhibitors induce the interphase transition by inactivating mitogen-activated protein kinase in mouse eggs.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Genistein; Immunoblotting; Indoles; Interphase; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Okadaic Acid; Ovum; Protein-Tyrosine Kinases; Staurosporine | 1998 |
Isometric contraction induces the Ca2+-independent activation of the endothelial nitric oxide synthase.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Aorta, Thoracic; Benzoquinones; Calcium; Calmodulin; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Female; Genistein; Hydroquinones; Imidazoles; In Vitro Techniques; Indoles; Isometric Contraction; Lactams, Macrocyclic; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Oxadiazoles; Oxazines; Quinones; Rabbits; Rifabutin; Staurosporine | 1999 |
Ethanol inhibits astroglial cell proliferation by disruption of phospholipase D-mediated signaling.
Topics: 1-Butanol; Animals; Astrocytes; Becaplermin; Butanols; Cell Division; Culture Media, Serum-Free; DNA; Endothelin-1; Ethanol; Fetal Alcohol Spectrum Disorders; Genistein; Growth Inhibitors; Indoles; Nerve Tissue Proteins; Phosphatidic Acids; Phospholipase D; Phosphorylation; Platelet-Derived Growth Factor; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-sis; Rats; Signal Transduction; tert-Butyl Alcohol; Vanadates | 1999 |
Stretch induces mitogen-activated protein kinase activation and myogenic tone through 2 distinct pathways.
Topics: Animals; Benzoquinones; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix; Flavonoids; Genistein; Indoles; Lactams, Macrocyclic; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle Tonus; Protein Kinase C; Quinones; Rabbits; Rifabutin; Temperature; Vasoconstriction; Veins | 1999 |
Activation of macrophage CD8: pharmacological studies of TNF and IL-1 beta production.
Topics: Androstadienes; Animals; CD8 Antigens; Dinoprostone; Enzyme Precursors; Flow Cytometry; Genistein; Indoles; Interleukin-1; Intracellular Signaling Peptides and Proteins; Macrophage Activation; Macrophages, Alveolar; Male; Oligonucleotides, Antisense; Phagocytosis; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; src-Family Kinases; Syk Kinase; Tumor Necrosis Factor-alpha; Wortmannin | 2000 |
Tyrosine phosphorylation of a 34-kDa protein induced by cross-linking a novel glycosylphosphatidylinositol-anchored glycoprotein (GPI-80) on human neutrophils that may regulate their adherence and migration.
Topics: Amidohydrolases; Androstadienes; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Chelating Agents; Cross-Linking Reagents; Cytochalasin B; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Genistein; GPI-Linked Proteins; Humans; Hydrolases; Indoles; Mice; Mice, Inbred BALB C; Neutrophils; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; Signal Transduction; Time Factors; Tyrosine; Vanadates; Virulence Factors, Bordetella; Wortmannin | 2000 |
Activation of protein kinase B by the A(1)-adenosine receptor in DDT(1)MF-2 cells.
Topics: Adenosine; Androstadienes; Animals; Calcium; Cell Line; Chromones; Cricetinae; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Imidazoles; Indoles; Insulin; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Morpholines; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyridines; Receptors, Purinergic P1; Virulence Factors, Bordetella; Wortmannin; Xanthines | 2000 |
Involvement of the mitogen-activated protein (MAP) kinase signalling pathway in host cell invasion by Toxoplasma gondii.
Topics: Animals; Bombesin; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Indoles; Mitogen-Activated Protein Kinases; Models, Biological; Signal Transduction; Tetradecanoylphorbol Acetate; Toxoplasma | 2000 |
Regulation of phenobarbital-induction of CYP2B and CYP3A genes in rat cultured hepatocytes: involvement of several serine/threonine protein kinases and phosphatases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aryl Hydrocarbon Hydroxylases; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Cyclic AMP; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Genistein; Hepatocytes; Hydroquinones; Indoles; Intracellular Fluid; Morpholines; Okadaic Acid; Oxidoreductases, N-Demethylating; Phenobarbital; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; RNA, Messenger; Signal Transduction | 2000 |
Sustained norepinephrine stimulation induces different regulation of expression in three alpha1-adrenoceptor subtypes.
Topics: Cell Line; Egtazic Acid; Genistein; Humans; Indoles; Kidney; Norepinephrine; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection; Tyrphostins | 2001 |
Homocysteine mediated expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human monocytes.
Topics: Antioxidants; Cells, Cultured; Chemokine CCL2; Chromans; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Genistein; Homocysteine; Humans; Imidazoles; Indoles; Interleukin-8; Monocytes; Naphthalenes; Onium Compounds; Pyridines; Pyrrolidines; Reactive Oxygen Species; RNA, Messenger; Sulfonamides; Thiazoles; Thiazolidinediones; Thiocarbamates; Time Factors; Troglitazone; Tyrphostins | 2003 |