ro 31-7549 has been researched along with ro 31-8220 in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (76.47) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, PD; Elliott, LH; Harris, W; Hill, CH; Hurst, SA; Keech, E; Kumar, MK; Lawton, G; Nixon, JS; Wilkinson, SE | 1 |
| Caivano, M; Cohen, P; Davies, SP; Reddy, H | 1 |
| Bullock, AN; Debreczeni, JE; Fedorov, OY; Knapp, S; Marsden, BD; Nelson, A | 1 |
| Balke-Want, H; Basu, D; Engel, J; Ercanoglu, MS; Rauh, D; Richters, A; Tesch, R; Thomas, RK | 1 |
| Gilfillan, AM; Lin, P | 1 |
| Carew, MA; Paleolog, EM; Pearson, JD | 1 |
| Murphy, CT; Westwick, J | 1 |
| Dieter, P; Fitzke, E | 1 |
| Bacon, KB; Camp, RD | 1 |
| Booth, RF; Brindle, NP; Evans, MA; Lim, K; Newby, AC | 1 |
| Barnes, PJ; Giembycz, MA; Hirst, SJ; Twort, CH; Webb, BL | 1 |
| Chopra, LC; Twort, CH; Ward, JP | 1 |
| Hawkins, PT; Jackson, TR; Stephens, L | 1 |
| Nixon, JS; Parker, PJ; Wilkinson, SE | 1 |
| Proud, CG; Welsh, GI | 1 |
| Meager, A; Mire-Sluis, A; Sampson, LE | 1 |
| Ali, A; Huang, WC; Lin, WW; Wen, HC; Woodgett, JR | 1 |
17 other study(ies) available for ro 31-7549 and ro 31-8220
| Article | Year |
|---|---|
Inhibitors of protein kinase C. 2. Substituted bisindolylmaleimides with improved potency and selectivity.
Topics: Animals; Cattle; Female; Humans; Maleimides; Models, Molecular; Protein Kinase C; Rats; Structure-Activity Relationship | 1992 |
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Amides; Animals; Benzamides; Benzophenanthridines; Benzopyrans; Butadienes; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Isoquinolines; Lithium; Magnesium; Nitriles; Phenanthridines; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Sirolimus; Substrate Specificity; Sulfonamides | 2000 |
Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase.
Topics: Antineoplastic Agents; Crystallization; Crystallography, X-Ray; Flavonoids; Humans; Imidazoles; Indoles; Maleimides; Models, Molecular; Molecular Structure; Moloney murine leukemia virus; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-pim-1; Proviruses; Pyrazoles; Pyridazines; Pyrimidines; Structure-Activity Relationship | 2005 |
Identification and further development of potent TBK1 inhibitors.
Topics: Animals; Cell Line; Drug Design; Humans; Macrophages; Mice; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Small Molecule Libraries; Structure-Activity Relationship | 2015 |
The role of calcium and protein kinase C in the IgE-dependent activation of phosphatidylcholine-specific phospholipase D in a rat mast (RBL 2H3) cell line.
Topics: Alkaloids; Animals; Calcium; Cell Line; Enzyme Activation; Histamine Release; Immunoglobulin E; Indoles; Ionomycin; Kinetics; Maleimides; Mast Cells; Phospholipase D; Protein Kinase C; Rats; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1992 |
The roles of protein kinase C and intracellular Ca2+ in the secretion of von Willebrand factor from human vascular endothelial cells.
Topics: Adenosine Triphosphate; Alkaloids; Calcimycin; Calcium; Cations, Divalent; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Humans; Indoles; Maleimides; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; von Willebrand Factor | 1992 |
Selective inhibition of protein kinase C. Effect on platelet-activating-factor-induced platelet functional responses.
Topics: Animals; Blood Platelets; Calcium; Enzyme Activation; Indoles; Kinetics; Maleimides; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Rabbits; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1992 |
RO 31-8220 and RO 31-7549 show improved selectivity for protein kinase C over staurosporine in macrophages.
Topics: Alkaloids; Animals; Cells, Cultured; Dinoprostone; Indoles; Kinetics; Macrophages; Maleimides; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Interleukin (IL)-8-induced in vitro human lymphocyte migration is inhibited by cholera and pertussis toxins and inhibitors of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Movement; Chemotactic Factors; Cholera Toxin; Cyclic AMP; Diglycerides; GTP-Binding Proteins; Humans; In Vitro Techniques; Indoles; Interleukin-8; Interleukins; Isoquinolines; Lymphocytes; Maleimides; Pertussis Toxin; Piperazines; Protein Kinase C; Sphingosine; Virulence Factors, Bordetella | 1990 |
Inhibition of rabbit aortic smooth muscle cell proliferation by selective inhibitors of protein kinase C.
Topics: Animals; Aorta; Cell Division; Cells, Cultured; Enzyme Inhibitors; Indoles; Maleimides; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Protein Kinase C; Rabbits; Serotonin; Thymidine | 1995 |
Inhibition of fetal calf serum-stimulated proliferation of rabbit cultured tracheal smooth muscle cells by selective inhibitors of protein kinase C and protein tyrosine kinase.
Topics: Animals; Asthma; Cell Division; Cells, Cultured; Cinnamates; Culture Media; Disease Models, Animal; DNA; Humans; Indoles; Maleimides; Muscle, Smooth; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; Sulfides; Tetradecanoylphorbol Acetate; Trachea | 1995 |
Differences in sensitivity to the specific protein kinase C inhibitor Ro31-8220 between small and large bronchioles of the rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bronchi; Bronchoconstriction; Carbachol; In Vitro Techniques; Indoles; Isoquinolines; Male; Maleimides; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Wistar; Serotonin | 1994 |
Activation of phosphatidylinositol 4,5-bisphosphate supply by agonists and non-hydrolysable GTP analogues.
Topics: Cell Membrane Permeability; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Indoles; Inositol; Inositol Phosphates; Kinetics; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphates; Phosphatidylinositol Phosphates; Phosphorus Radioisotopes; Protein Kinase C; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Binding Sites; Binding, Competitive; Brain; Indoles; Isoenzymes; Maleimides; Molecular Conformation; Protein Kinase C; Rats; Staurosporine; Structure-Activity Relationship | 1993 |
Evidence for a role for protein kinase C in the stimulation of protein synthesis by insulin in swiss 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Guanine Nucleotide Exchange Factors; In Vitro Techniques; Indoles; Insulin; Maleimides; Mice; Phorbol 12,13-Dibutyrate; Protein Biosynthesis; Protein Kinase C; Protein-Tyrosine Kinases; Proteins; Receptor, Insulin | 1993 |
Protein kinase C-dependent phosphorylation is involved in resistance to tumour necrosis factor-alpha-induced cytotoxicity in a human monocytoid cell line.
Topics: Cell Survival; Drug Resistance; Humans; Hybrid Cells; Indoles; Maleimides; Phosphoproteins; Phosphorylation; Protein Kinase C; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Negative regulation of phosphatidylinositol 3-kinase and Akt signalling pathway by PKC.
Topics: Androstadienes; Cell Line; Down-Regulation; Enzyme Inhibitors; Epithelial Cells; Humans; Indoles; Maleimides; Mesylates; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrroles; Serine; Signal Transduction; Wortmannin | 2003 |