Compounds > ro 24-4736
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ro 24-4736 and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine

ro 24-4736 has been researched along with 1-hexadecyl-2-acetyl-glycero-3-phosphocholine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burghardt, C; Crowley, HJ; Janero, DR; O'Donnell, M; Selig, WM; Welton, AF; Yaremko, B1
O'Donnell, M1
Elder, CA; Modi, MW1
Ayala, A; Chaudry, IH; Morrison, MH; Schmand, JF; Zellweger, R1
Cashin, C; Newbold, P; O'Donnell, M; Renzetti, L; Simko, B; Tocker, J; Wasserman, MA; Welton, AF1
Anastasi, EM; Chang, D; Liberato, DJ; Loh, AC; Sasso, GJ; Williams, TH1
Chesonis, RS; Harbison, ML; Schmolze, D; Symington, J; Thomas, TK; Walser, A; Will, PC1
Coyle, S; Felsen, D; Lowry, SF; Moldawer, L; Oldenburg, H; Rogy, M; Thompson, WA; Trousdale, R; Van Zee, K1
Bonventre, JV; Christenson, JG; Kelly, KJ; Meehan, SM; Meschter, CL; Rubin, RH; Tolkoff-Rubin, NE; Williams, WW1
Bolognese, B; Hubbard, WC; Jackson, JR; Mangar, CA; Marshall, LA; Winkler, JD1

Trials

1 trial(s) available for ro 24-4736 and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine

ArticleYear
The metabolic effects of platelet-activating factor antagonism in endotoxemic man.
    Archives of surgery (Chicago, Ill. : 1960), 1994, Volume: 129, Issue:1

    Topics: Adult; Cytokines; Double-Blind Method; Endotoxins; Hormones; Humans; Lipopolysaccharides; Male; Phenanthridines; Platelet Activating Factor; Platelet Aggregation; Toxemia; Triazines

1994

Other Studies

9 other study(ies) available for ro 24-4736 and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine

ArticleYear
Pharmacology of a potent platelet-activating factor antagonist: Ro 24-4736.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:1

    Topics: Animals; Azepines; Binding Sites; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Dogs; Guinea Pigs; Humans; Male; Phenanthridines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazines; Triazoles

1991
Effects of Ro 24-4736 in antagonizing the platelet and bronchoconstrictor responses to PAF.
    Annals of the New York Academy of Sciences, 1991, Volume: 629

    Topics: Animals; Binding, Competitive; Blood Platelets; Bronchoconstriction; Bronchodilator Agents; Dogs; Guinea Pigs; Humans; Phenanthridines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazines

1991
Interspecies scaling of a thienodiazepine platelet-activating factor receptor antagonist.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:7

    Topics: Animals; Azepines; Bronchodilator Agents; Dogs; Half-Life; Humans; Papio; Phenanthridines; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Regression Analysis; Saimiri; Species Specificity; Tranquilizing Agents; Triazines

1995
PAF-antagonist administration after hemorrhage-resuscitation prevents splenocyte immunodepression.
    The Journal of surgical research, 1995, Volume: 59, Issue:3

    Topics: Animals; Hemorrhage; Immune Tolerance; Interleukin-2; Interleukin-3; Lymphokines; Male; Mice; Mice, Inbred C3H; Phenanthridines; Platelet Activating Factor; Spleen; Triazines

1995
Studies of the combination of Ro 24-5913, a peptidoleukotriene antagonist, and Ro 24-4736, a PAF antagonist, in guinea pig and rat models of lung inflammation.
    Annals of the New York Academy of Sciences, 1994, Nov-15, Volume: 744

    Topics: Animals; Bronchoconstriction; Guinea Pigs; Lung; Male; Phenanthridines; Platelet Activating Factor; Pneumonia; Rats; SRS-A; Thiazoles; Triazines

1994
Disposition and metabolism of Ro 24-4736 in the rat.
    Life sciences, 1994, Volume: 54, Issue:26

    Topics: Animals; Biotransformation; Carbon Radioisotopes; Injections, Intravenous; Liver; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Phenanthridines; Phenobarbital; Platelet Activating Factor; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; Tissue Distribution; Triazines

1994
Differential antagonism of platelet activating factor-induced neutrophilia and gastric hemorrhage in the rat.
    Agents and actions, 1993, Volume: 39 Spec No

    Topics: Animals; Gastric Mucosa; Gastrointestinal Hemorrhage; Hemoglobins; Hypotension; Injections, Intravenous; Male; Neutrophils; Phenanthridines; Phospholipid Ethers; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Triazines

1993
An oral platelet-activating factor antagonist, Ro-24-4736, protects the rat kidney from ischemic injury.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 2

    Topics: Acute Kidney Injury; Administration, Oral; Animals; Antibodies; Dose-Response Relationship, Drug; Intercellular Adhesion Molecule-1; Ischemia; Kidney; Male; Peroxidase; Phenanthridines; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion; Triazines

1996
The role of platelet activating factor and other lipid mediators in inflammatory angiogenesis.
    Biochimica et biophysica acta, 1998, May-20, Volume: 1392, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Granuloma; Hydroxyurea; Inflammation Mediators; Leukotrienes; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Phenanthridines; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Sulfonamides; Triazines

1998