ro 22-1319 has been researched along with spiperone in 4 studies
| Studies (ro 22-1319) | Trials (ro 22-1319) | Recent Studies (post-2010) (ro 22-1319) | Studies (spiperone) | Trials (spiperone) | Recent Studies (post-2010) (spiperone) |
|---|---|---|---|---|---|
| 23 | 3 | 0 | 2,944 | 13 | 85 |
| Protein | Taxonomy | ro 22-1319 (IC50) | spiperone (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0008 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| D(4) dopamine receptor | Homo sapiens (human) | 0.0005 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | 0.097 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0635 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.097 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0001 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.955 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murray, AM; Waddington, JL | 1 |
| Iwata, K; Nakajima, T | 1 |
| O'Boyle, KM; Waddington, JL | 1 |
| Cody, V; Froimowitz, M | 1 |
4 other study(ies) available for ro 22-1319 and spiperone
| Article | Year |
|---|---|
The induction of grooming and vacuous chewing by a series of selective D-1 dopamine receptor agonists: two directions of D-1:D-2 interaction.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Corpus Striatum; Dopamine Agents; Dose-Response Relationship, Drug; Grooming; Isoquinolines; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior | 1989 |
[3H]Ro 22-1319 (piquindone) binds to the D2 dopaminergic receptor subtype in a sodium-dependent manner.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Brain; Cations, Monovalent; Cattle; Corpus Striatum; Isoquinolines; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Sodium; Spiperone; Tissue Distribution | 1984 |
Identification of the enantiomers of SK&F 83566 as specific and stereoselective antagonists at the striatal D-1 dopamine receptor: comparisons with the D-2 enantioselectivity of Ro 22-1319.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Benzazepines; Binding, Competitive; Corpus Striatum; In Vitro Techniques; Isoquinolines; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Stereoisomerism; Thioxanthenes | 1984 |
The incorporation of butyrophenones and related compounds into a pharmacophore for dopamine D2 antagonists.
Topics: Antipsychotic Agents; Benzimidazoles; Butyrophenones; Dopamine Antagonists; Drug Design; Isoquinolines; Models, Molecular; Molecular Conformation; Molindone; Receptors, Dopamine D2; Spiperone | 1997 |