ro 19-3704 has been researched along with 1-hexadecyl-2-acetyl-glycero-3-phosphocholine in 13 studies
| Studies (ro 19-3704) | Trials (ro 19-3704) | Recent Studies (post-2010) (ro 19-3704) | Studies (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Trials (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) | Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine) |
|---|---|---|---|---|---|
| 14 | 0 | 0 | 9,156 | 187 | 552 |
| Protein | Taxonomy | ro 19-3704 (IC50) | 1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50) |
|---|---|---|---|
| Platelet-activating factor receptor | Homo sapiens (human) | 0.0003 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adler, KB; Akley, NJ; Glasgow, WC | 1 |
| Bin, Z; Kun, L | 1 |
| Cavero, I; Floch, A; Sedivy, P; Tahraoui, L | 1 |
| Gilfillan, AM; Hope, WC; Patel, BJ; Welton, AF; Wiggan, GA | 1 |
| Bertrand, C; Landry, Y; Tschirhart, E | 1 |
| Kaliner, M; Logun, C; Lundgren, JD; Shelhamer, JH | 1 |
| Goswami, SK; Marom, ZM; Ohashi, M; Stathas, P | 1 |
| Ferracin, F; Gurari-Rotman, D; Pletscher, A | 1 |
| Fouque, F; Parini, A; Schattner, M; Touqui, L; Vargaftig, BB | 1 |
| Adnot, S; Joseph, D; Vargaftig, BB | 1 |
| Lagente, V; Steel, G; Vargaftig, B; Wallace, JL; Whittle, BJ | 1 |
| Cirino, M; Desquand, S; Hadvary, P; Lagente, V; Lefort, J; Lellouch-Tubiana, A; Vargaftig, BB | 1 |
| Bon, C; Faili, A; Hatmi, M; Mounier, C; Vargaftig, BB | 1 |
13 other study(ies) available for ro 19-3704 and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
| Article | Year |
|---|---|
Platelet-activating factor provokes release of mucin-like glycoproteins from guinea pig respiratory epithelial cells via a lipoxygenase-dependent mechanism.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Epithelium; Glyceryl Ethers; Guinea Pigs; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indomethacin; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Mucins; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Trachea | 1992 |
Inhibition by glaucocalyxin A of aggregation of rabbit platelets induced by ADP, arachidonic acid and platelet-activating factor, and inhibition of [3H]-PAF binding.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Blood Platelets; Diterpenes, Kaurane; Drugs, Chinese Herbal; Female; Glyceryl Ethers; In Vitro Techniques; Kinetics; Male; Molecular Structure; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Thiazoles | 1992 |
The platelet activating factor receptor antagonist, RP 59227, blocks platelet activating factor receptors mediating liberation of reactive oxygen species in guinea pig macrophages and human polymorphonuclear leukocytes.
Topics: Animals; Azepines; Glyceryl Ethers; Guinea Pigs; Humans; Luminescent Measurements; Macrophages; Male; Neutrophils; Oxygen; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Radioligand Assay; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Triazoles | 1991 |
Ro 19-3704 directly inhibits immunoglobulin E-dependent mediator release by a mechanism independent of its platelet-activating factor antagonist properties.
Topics: Animals; Azepines; Diterpenes; Ginkgolides; Glyceryl Ethers; Histamine Release; Humans; Immunoglobulin E; Inositol Phosphates; L-Lactate Dehydrogenase; Lactones; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Substance P; Synovial Fluid; Thiazoles; Triazines; Triazoles; Tumor Cells, Cultured | 1990 |
Selective implication of thromboxane A2 and PAF-acether in two guinea pig anaphylactic models.
Topics: Anaphylaxis; Animals; Antigens; Glyceryl Ethers; Guinea Pigs; Immunoglobulin E; Immunoglobulin G; In Vitro Techniques; Indomethacin; Muscle Contraction; Platelet Activating Factor; Thiazoles; Thromboxane A2; Trachea | 1990 |
Platelet activating factor and tracheobronchial respiratory glycoconjugate release in feline and human explants: involvement of the lipoxygenase pathway.
Topics: Animals; Bronchi; Cats; Culture Techniques; Glyceryl Ethers; Glycoconjugates; Humans; Ibuprofen; Lipoxygenase; Masoprocol; Platelet Activating Factor; Thiazoles; Trachea; Tritium | 1990 |
Platelet-activating factor stimulates secretion of respiratory glycoconjugate from human airways in culture.
Topics: Arachidonic Acids; Atropine; Bronchi; Culture Techniques; Cyclooxygenase Inhibitors; Dexamethasone; Dose-Response Relationship, Drug; Glyceryl Ethers; Glycoconjugates; Histamine Release; Humans; Leukotrienes; Lipoxygenase Inhibitors; Mucous Membrane; Platelet Activating Factor; Thiazoles; Time Factors | 1989 |
LDL induced shape change reaction of platelets is not due to PAF.
Topics: Azepines; Blood Platelets; Glyceryl Ethers; Humans; In Vitro Techniques; Lipoproteins, LDL; Platelet Activating Factor; Thiazoles; Thienopyridines; Triazolam | 1989 |
Selective inhibition of adrenaline-induced human platelet aggregation by the structurally related Paf antagonist Ro 19-3704.
Topics: 5-Hydroxytryptophan; Binding, Competitive; Diterpenes; Drug Synergism; Epinephrine; Ginkgolides; Glyceryl Ethers; Humans; In Vitro Techniques; Lactones; Morpholines; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Thiazoles; Yohimbine | 1989 |
Antagonists of PAF-acether do not suppress thrombin-induced aggregation of ADP-deprived and aspirin-treated human platelets.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aspirin; Blood Platelets; Crotalid Venoms; Cyclooxygenase Inhibitors; Diterpenes; Ginkgolides; Glyceryl Ethers; Humans; Lactones; Lectins, C-Type; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Platelet Aggregation; Pyridines; Thiazoles; Thrombin | 1987 |
Evidence for platelet-activating factor as a mediator of endotoxin-induced gastrointestinal damage in the rat. Effects of three platelet-activating factor antagonists.
Topics: Animals; Blood Pressure; Disease Models, Animal; Diterpenes; Escherichia coli Infections; Ethanol; Ginkgolides; Glyceryl Ethers; Intestine, Small; Lactones; Lipopolysaccharides; Male; Peptic Ulcer; Peptic Ulcer Hemorrhage; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic; Stomach; Thiazoles | 1987 |
Interference of the Paf antagonist Ro 19-3704 with Paf and antigen-induced bronchoconstriction in the guinea-pig.
Topics: Aerosols; Animals; Blood Cell Count; Bronchodilator Agents; Female; Glyceryl Ethers; Guinea Pigs; In Vitro Techniques; Macrophage Activation; Macrophages; Male; Ovalbumin; Phospholipid Ethers; Platelet Activating Factor; Pulmonary Alveoli; Thiazoles | 1988 |
Competitive inhibition of phospholipase A2 activity by the platelet-activating factor antagonist Ro 19-3704 and evidence for a novel suppressive effect on platelet activation.
Topics: Animals; Arachidonic Acid; Blood Platelets; Glyceryl Ethers; Male; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Platelet Activation; Rabbits; Serum Albumin, Bovine; Thiazoles | 1993 |