Compounds > ro 15-4513
Page last updated: 2024-08-16

ro 15-4513 and pentobarbital

ro 15-4513 has been researched along with pentobarbital in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199014 (53.85)18.7374
1990's8 (30.77)18.2507
2000's3 (11.54)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dar, MS1
Boix, F; Escorihuela, RM; Fernández-Teruel, A; Núñez, JF; Salazar, W; Tobeña, A; Zapata, A1
Budhram, P; Deacon, RM; Gardner, CR; Thomson, TA1
Koob, GF; Schreiber, JF; Weinger, MB1
Biggio, G; Corda, MG; Giorgi, O; Longoni, B1
Durcan, MJ; Linnoila, M; Lister, RG; Wozniak, KM1
Michael, RP; Schaefer, GJ1
Kalant, H; Khanna, JM; Le, AD; Mana, MJ; Pham, T1
Kulkarni, SK; Ticku, MK1
Allan, AM; Daniell, LC; Harris, RA; Nixon, C1
Lister, RG; Nutt, DJ3
Crawley, J; Glowa, JR; Paul, SM; Suzdak, PD1
Hiltunen, AJ; Järbe, TU1
Britton, KT; Koob, GF; Percy, L1
Hoffman, PL; Paul, SM; Suzdak, PD; Szabó, G; Tabakoff, B1
Lister, RG1
Ho, IK; Ito, T; Suzuki, T; Wellman, SE1
Anderson, S; Stone, T; Yutrzenka, GJ1
Anwer, J; Dar, MS; Meng, ZH1
Davies, M; Dunn, SM; Thuynsma, RP1
France, CP; McMahon, LR1
France, CP; Gerak, LR; McMahon, LR1
Grant, KA; Helms, CM; Rogers, LS1
Contó, MB; de Carvalho, JG; Hipólide, DC; Venditti, MA1

Reviews

1 review(s) available for ro 15-4513 and pentobarbital

ArticleYear
RO 15-4513 and its interaction with ethanol.
    Advances in alcohol & substance abuse, 1988, Volume: 7, Issue:3-4

    Topics: Animals; Azides; Benzodiazepines; Drug Interactions; Ethanol; Mice; Pentobarbital; Rats; Receptors, GABA-A; Saimiri

1988

Other Studies

25 other study(ies) available for ro 15-4513 and pentobarbital

ArticleYear
Selective antagonism of acute ethanol-induced motor disturbances by centrally administered Ro 15-4513 in mice.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:3

    Topics: Animals; Azides; Benzodiazepines; Dose-Response Relationship, Drug; Electrodes, Implanted; Ethanol; Injections, Intraventricular; Male; Mice; Motor Activity; Pentobarbital; Pentylenetetrazole; Psychomotor Performance; Seizures

1992
The early acquisition of two-way (shuttle-box) avoidance as an anxiety-mediated behavior: psychopharmacological validation.
    Brain research bulletin, 1991, Volume: 26, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Azides; Benzodiazepines; Carbolines; Male; Pentobarbital; Rats; Rats, Inbred Strains

1991
Differential interactions of Ro 15-4513 with benzodiazepines, ethanol and pentobarbital.
    European journal of pharmacology, 1990, May-16, Volume: 180, Issue:2-3

    Topics: Anesthesia; Animals; Anti-Anxiety Agents; Azides; Behavior, Animal; Benzodiazepines; Diazepam; Drug Interactions; Ethanol; Female; Flumazenil; Male; Muscle Contraction; Muscles; Pentobarbital; Rats; Rats, Inbred Strains; Urethane; Vocalization, Animal

1990
Effects of two benzodiazepine inverse agonists, RO 15-4513 and FG 7142, on recovery from pentobarbital and halothane anesthesia in the rat.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:4

    Topics: Anesthesia Recovery Period; Animals; Azides; Benzodiazepines; Carbolines; Flumazenil; Halothane; Male; Pentobarbital; Random Allocation; Rats; Rats, Inbred Strains; Reflex

1990
Ro 15-4513, a partial inverse agonist for benzodiazepine recognition sites, has proconflict and proconvulsant effects in the rat.
    European journal of pharmacology, 1989, Jan-17, Volume: 159, Issue:3

    Topics: Animals; Azides; Benzodiazepines; Carbolines; Conflict, Psychological; Convulsants; Flumazenil; Isoniazid; Male; Pentobarbital; Punishment; Rats; Rats, Inbred Strains; Receptors, GABA-A

1989
Attenuation of hypothermic effects of ethanol by alpha 2-adrenoceptor blockers.
    European journal of pharmacology, 1989, Aug-03, Volume: 166, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Azides; Benzodiazepines; Body Temperature; Dioxanes; Dose-Response Relationship, Drug; Ethanol; Idazoxan; Imidazoles; Male; Mice; Pentobarbital; Time Factors

1989
Interactions of diazepam and pentobarbital with RO 15-4513 on intracranial self-stimulation discrimination behavior in rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:1

    Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Brain; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Male; Pentobarbital; Rats; Rats, Inbred Strains; Self Stimulation

1989
Effects of Ro 15-4513 on the motor impairment and hypnotic effects of ethanol and pentobarbital.
    European journal of pharmacology, 1989, Jan-02, Volume: 159, Issue:1

    Topics: Animals; Azides; Benzodiazepines; Ethanol; Hypnotics and Sedatives; Male; Pentobarbital; Psychomotor Performance; Rats; Rats, Inbred Strains

1989
RO15-4513 but not FG-7142 reverses anticonvulsant effects of ethanol against bicuculline- and picrotoxin-induced convulsions in rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:1

    Topics: Affinity Labels; Animals; Appetite Depressants; Azides; Benzodiazepines; Bicuculline; Carbolines; Ethanol; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Seizures

1989
Antagonism of ethanol and pentobarbital actions by benzodiazepine inverse agonists: neurochemical studies.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:3

    Topics: Animals; Azides; Benzodiazepines; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Carbolines; Chloride Channels; Chlorides; Ethanol; Male; Membrane Fluidity; Membrane Proteins; Mice; Mice, Inbred ICR; Pentobarbital; Receptors, GABA-A

1988
Antagonizing the anticonvulsant effect of ethanol using drugs acting at the benzodiazepine/GABA receptor complex.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:3

    Topics: Animals; Anticonvulsants; Azides; Benzodiazepines; Benzodiazepinones; Carbolines; Convulsants; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Pentobarbital; Receptors, GABA-A; Seizures

1988
Ethanol and the GABA receptor complex: studies with the partial inverse benzodiazepine receptor agonist Ro 15-4513.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:3

    Topics: Alcoholic Intoxication; Animals; Azides; Behavior, Animal; Benzodiazepines; Chlorine; Conflict, Psychological; Dose-Response Relationship, Drug; Ethanol; Male; Meta-Analysis as Topic; Mice; Pentobarbital; Rats; Receptors, GABA-A; Time Factors

1988
The effect of the imidazodiazepine Ro 15-4513 on the anticonvulsant effects of diazepam, sodium pentobarbital and ethanol.
    Brain research, 1987, Jun-09, Volume: 413, Issue:1

    Topics: Animals; Azides; Benzodiazepines; Convulsants; Diazepam; Ethanol; Ligands; Male; Mice; Pentobarbital; Receptors, GABA-A

1987
Effects of Ro 15-4513, alone or in combination with ethanol, Ro 15-1788, diazepam, and pentobarbital on instrumental behaviors of rats.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:3

    Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Female; Flumazenil; Pentobarbital; Rats; Rats, Inbred Strains; Time Factors

1988
The effects of Ro 15-4513 on the behavioral actions of ethanol in an operant reaction time task and a conflict test.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:3

    Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Chlordiazepoxide; Conditioning, Operant; Conflict, Psychological; Dose-Response Relationship, Drug; Ethanol; Male; Motor Activity; Pentobarbital; Rats; Rats, Inbred Strains; Reaction Time

1988
Effect of an imidazobenzodiazepine, Ro15-4513, on the incoordination and hypothermia produced by ethanol and pentobarbital.
    Life sciences, 1987, Aug-03, Volume: 41, Issue:5

    Topics: Animals; Azides; Benzodiazepines; Body Temperature Regulation; Ethanol; Hypothermia; Kinetics; Male; Mice; Mice, Inbred C57BL; Pentobarbital; Time Factors

1987
Interactions of Ro 15-4513 with diazepam, sodium pentobarbital and ethanol in a holeboard test.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:1

    Topics: Animals; Azides; Benzodiazepines; Diazepam; Drug Interactions; Ethanol; Exploratory Behavior; Head; Male; Mice; Motor Activity; Pentobarbital; Posture

1987
Chronic pentobarbital administration alters gamma-aminobutyric acidA receptor alpha 6-subunit mRNA levels and diazepam-insensitive [3H]Ro15-4513 binding.
    Synapse (New York, N.Y.), 1996, Volume: 22, Issue:2

    Topics: Animals; Autoradiography; Azides; Benzodiazepines; Binding, Competitive; Diazepam; In Situ Hybridization; Male; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger

1996
Ro 15-4513 alteration of pentobarbital dependence.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 55, Issue:3

    Topics: Animals; Azides; Benzodiazepines; Dose-Response Relationship, Drug; Drug Interactions; Male; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors; Weight Loss

1996
The striatal adenosinergic modulation of ethanol-induced motor incoordination in rats: possible role of chloride flux.
    Brain research, 1997, Nov-21, Volume: 776, Issue:1-2

    Topics: Adenosine; Affinity Labels; Animals; Azides; Benzodiazepines; Central Nervous System Depressants; Cerebrospinal Fluid; Chlorides; Corpus Striatum; Ethanol; GABA Modulators; Male; Microdialysis; Motor Activity; Pentobarbital; Radioisotopes; Rats; Rats, Sprague-Dawley; Xanthines

1997
Effects of propofol and pentobarbital on ligand binding to GABAA receptors suggest a similar mechanism of action.
    Canadian journal of physiology and pharmacology, 1998, Volume: 76, Issue:1

    Topics: Allosteric Site; Anesthetics, Intravenous; Animals; Azides; Benzodiazepines; Brain; Cattle; Flunitrazepam; GABA Agonists; In Vitro Techniques; Ligands; Membranes; Muscimol; Pentobarbital; Propofol; Receptors, GABA-A

1998
Daily treatment with diazepam differentially modifies sensitivity to the effects of gamma-aminobutyric acid(A) modulators on schedule-controlled responding in rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:3

    Topics: Animals; Azides; Benzodiazepines; Carbolines; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Electroshock; Food; GABA Agonists; GABA Antagonists; GABA Modulators; Macaca mulatta; Male; Pentobarbital; Pregnanolone; Receptors, GABA-A; Reinforcement Schedule; Triazolam

2002
Efficacy and the discriminative stimulus effects of negative GABAA modulators, or inverse agonists, in diazepam-treated rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:2

    Topics: Animals; Azides; Benzodiazepines; Conditioning, Operant; Cues; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Agonists; GABA Modulators; Hypnotics and Sedatives; Macaca mulatta; Male; Pentobarbital; Pregnanolone; Receptors, GABA-A

2006
Antagonism of the ethanol-like discriminative stimulus effects of ethanol, pentobarbital, and midazolam in cynomolgus monkeys reveals involvement of specific GABA(A) receptor subtypes.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 331, Issue:1

    Topics: Animals; Azides; Benzodiazepines; Discrimination Learning; Dose-Response Relationship, Drug; Ethanol; Female; Flumazenil; Macaca fascicularis; Male; Midazolam; Pentobarbital; Protein Subunits; Receptors, GABA-A

2009
Rats with different thresholds for DMCM-induced clonic convulsions differ in the sleep-time of diazepam and [(3)H]-Ro 15-4513 binding.
    Epilepsy research, 2012, Volume: 98, Issue:2-3

    Topics: Animals; Anticonvulsants; Autoradiography; Azides; Benzodiazepines; Carbolines; Convulsants; Diazepam; Differential Threshold; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Flunitrazepam; GABA Modulators; Male; Pentobarbital; Rats; Rats, Wistar; Reaction Time; Seizures; Sleep; Statistics, Nonparametric; Tritium

2012