Compounds > ro 15-0216
Page last updated: 2024-09-04

ro 15-0216 and suramin

ro 15-0216 has been researched along with suramin in 3 studies

Compound Research Comparison

Studies
(ro 15-0216)		Trials
(ro 15-0216)		Recent Studies (post-2010)
(ro 15-0216)		Studies
(suramin)		Trials
(suramin)		Recent Studies (post-2010) (suramin)
12003,02392431

Protein Interaction Comparison

ProteinTaxonomyro 15-0216 (IC50)suramin (IC50)
ATP-dependent 6-phosphofructokinaseTrypanosoma brucei brucei3
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)9.76
P2X purinoceptor 2Rattus norvegicus (Norway rat)4
DNA-dependent protein kinase catalytic subunitHomo sapiens (human)1.7
DNA primaseMycobacterium tuberculosis CDC15518.2
RmtAAspergillus nidulans5.9
Reverse transcriptase/RNaseH Human immunodeficiency virus 19.4
NAD-dependent protein deacetylase sirtuin-2Homo sapiens (human)1.15
NAD-dependent protein deacetylase sirtuin-1Homo sapiens (human)1.5667
Protein arginine N-methyltransferase 1Homo sapiens (human)5.33
NAD-dependent protein deacylase sirtuin-5, mitochondrialHomo sapiens (human)2.5

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bouteille, B; Darde, ML; Pestre-Alexandre, M1
Röttcher, D; Zweygarth, E1
Bouteille, B; Dumas, M1

Other Studies

3 other study(ies) available for ro 15-0216 and suramin

ArticleYear
[Action of drugs tested in an acellular medium and in mice infected with Trypanosoma brucei brucei].
    Bulletin de la Societe de pathologie exotique et de ses filiales, 1988, Volume: 81, Issue:3 Pt 2

    Topics: Acetanilides; Animals; Culture Media; Cyclosporins; Eflornithine; In Vitro Techniques; Melarsoprol; Mice; Mitoguazone; Nitroimidazoles; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1988
Trypanocidal activity of a 5-substituted 2-nitroimidazole compound (Ro 15-0216) in mice.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1987, Volume: 38, Issue:3

    Topics: Acetanilides; Animals; Drug Therapy, Combination; Female; Male; Mice; Nitroimidazoles; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African

1987
Treatment of human African trypanosomiasis.
    Bulletin of the World Health Organization, 2000, Volume: 78, Issue:12

    Topics: Acetanilides; Africa; Humans; Melarsoprol; Nitroimidazoles; Pentamidine; Suramin; Thiadiazoles; Trypanocidal Agents; Trypanosomiasis, African

2000