ro 12-5637 has been researched along with moclobemide in 5 studies
*Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties. [MeSH]
*Moclobemide: A reversible inhibitor of monoamine oxidase type A; (RIMA); (see MONOAMINE OXIDASE INHIBITORS) that has antidepressive properties. [MeSH]
| Studies (ro 12-5637) | Trials (ro 12-5637) | Recent Studies (post-2010) (ro 12-5637) | Studies (moclobemide) | Trials (moclobemide) | Recent Studies (post-2010) (moclobemide) |
|---|---|---|---|---|---|
| 5 | 1 | 0 | 788 | 240 | 113 |
| Protein | Taxonomy | ro 12-5637 (IC50) | moclobemide (IC50) |
|---|---|---|---|
| Amine oxidase [flavin-containing] A | Rattus norvegicus (Norway rat) | 7.7 | |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | 4.1522 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chavinie, J; Francoual, C; Moran, C; Olive, G; Pedarriosse, AM; Pfefen, JP; Pons, G; Schoerlin, MP; Tam, YK | 1 |
| Bae, KS; Cho, JY; Jang, IJ; Lee, KH; Park, JY; Park, SS; Shin, SG; Yi, SY; Yim, DS; Yu, KS | 1 |
| Gross, AS; Hoskins, JM; Rivory, LP; Shenfield, GM | 1 |
| Gross, A; Hoskins, J; Murray, M; Shenfield, G | 1 |
| Miljkovic, B; Pokrajac, M; Rakic, A; Vucicevic, K | 1 |
1 trial(s) available for ro 12-5637 and moclobemide
| Article | Year |
|---|---|
Effect of omeprazole on the pharmacokinetics of moclobemide according to the genetic polymorphism of CYP2C19.
Topics: Adult; Antidepressive Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Benzamides; Cross-Over Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Genotype; Humans; Mixed Function Oxygenases; Moclobemide; Morpholines; Omeprazole; Polymorphism, Genetic; Random Allocation | 2001 |
4 other study(ies) available for ro 12-5637 and moclobemide
| Article | Year |
|---|---|
Moclobemide excretion in human breast milk.
Topics: Adult; Benzamides; Biological Availability; Biotransformation; Female; Humans; Milk, Human; Moclobemide; Monoamine Oxidase Inhibitors; Morpholines | 1990 |
High-performance liquid chromatography-electrospray ionization mass spectrometry method for the measurement of moclobemide and two metabolites in plasma.
Topics: Antidepressive Agents; Benzamides; Chromatography, High Pressure Liquid; Drug Stability; Humans; Moclobemide; Morpholines; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2001 |
Characterization of moclobemide N-oxidation in human liver microsomes.
Topics: Benzamides; Catalysis; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Hot Temperature; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Microsomes, Liver; Moclobemide; Models, Chemical; Monoamine Oxidase Inhibitors; Morpholines; Oxygen; Protein Isoforms; Temperature; Time Factors | 2001 |
High-performance liquid chromatographic method for the determination of moclobemide and its two major metabolites in human plasma.
Topics: Benzamides; Blood; Chromatography, High Pressure Liquid; Humans; Moclobemide; Molecular Structure; Morpholines; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2007 |