ro-09-1437 has been researched along with clorobiocin* in 1 studies
1 other study(ies) available for ro-09-1437 and clorobiocin
Article | Year |
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Structure-activity relationship in two series of aminoalkyl substituted coumarin inhibitors of gyrase B.
Two series of aminosubstituted coumarins were synthesised and evaluated in vitro as inhibitors of DNA gyrase and as potential antibacterials. Novel novobiocin-like coumarins, 4-(dialkylamino)methylcoumarins and 4-((2-alkylamino)ethoxy)coumarins, were discovered as gyrase B inhibitors with promising antibacterial activity in vitro. Topics: Anti-Bacterial Agents; Coumarins; DNA Gyrase; DNA, Superhelical; Enzyme Inhibitors; Escherichia coli; Gram-Positive Bacteria; Molecular Structure; Novobiocin; Peptides, Cyclic; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1999 |