ro 09-1390 has been researched along with fluorouracil in 3 studies
*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]
*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Araya, S; Fukumoto, M; Hayashi, H; Kawabata, K; Kimura, H; Masai, Y; Meyer, C; Nio, Y; Tseng, CC; Tsubono, M | 1 |
Eda, H; Fujimoto, K; Ishida, M; Ishitsuka, H; Miwa, M; Ninomiya, Y; Sahara, H; Umeda, I; Yokose, K | 1 |
Taguchi, T | 1 |
1 review(s) available for ro 09-1390 and fluorouracil
Article | Year |
---|---|
[Development of fluorinated pyrimidines in Japan].
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Deoxycytidine; Drug Combinations; Fluorodeoxyuridylate; Fluorouracil; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasms; Neoplasms, Experimental; Oxonic Acid; Pyridines; Rats; Tegafur | 1993 |
2 other study(ies) available for ro 09-1390 and fluorouracil
Article | Year |
---|---|
A comparative study of the antitumor activities of 5'-deoxy-5-fluorouridine and its prodrug trimethoxybenzoyl-5'-deoxy-5-fluorocytidine (Ro09-1390) on human digestive organ cancer xenograft lines transplanted into nude mice.
Topics: Animals; Antineoplastic Agents; Deoxycytidine; Digestive System Neoplasms; Floxuridine; Fluorouracil; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Prodrugs; Transplantation, Heterologous | 1992 |
Comparative antitumor activity and intestinal toxicity of 5'-deoxy-5-fluorouridine and its prodrug trimethoxybenzoyl-5'-deoxy-5-fluorocytidine.
Topics: Animals; Antineoplastic Agents; Deoxycytidine; Floxuridine; Fluorouracil; Intestines; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Prodrugs | 1990 |