rn-1747 and pregnenolone-sulfate

rn-1747 has been researched along with pregnenolone-sulfate* in 1 studies

Other Studies

1 other study(ies) available for rn-1747 and pregnenolone-sulfate

Article	Year
Calcium, Sodium, and Transient Receptor Potential Channel Expression in Human Fetal Midbrain-Derived Neural Progenitor Cells. Stem cells and development, 2018, 07-15, Volume: 27, Issue:14 Voltage-gated sodium and calcium channels as well as transient receptor potential (TRP) channels are expressed during the differentiation of human neural progenitor cells (hNPCs) and are likely to be involved in regulating neurogenesis. However, the molecular composition of these ion channels in proliferating and differentiating hNPCs is largely unknown. In this study, we investigated fetal mesencephalic hNPCs in respect to their sodium, calcium, and TRP channel subunit expression and function. Quantitative real-time polymerase chain reaction indicated a significant upregulation of voltage-gated sodium and calcium channel subunits in hNPCs after differentiation for 3 weeks in vitro. In contrast, the TRP channel expression did not increase significantly during hNPC maturation. Intracellular Ca Topics: Calcium Channels; Cell Differentiation; Cell Proliferation; Fetus; Gene Expression Regulation, Developmental; Humans; Mesencephalon; Neural Stem Cells; Pregnenolone; Stem Cells; Sulfonamides; TRPA1 Cation Channel; Voltage-Gated Sodium Channels	2018

Article

Year

Calcium, Sodium, and Transient Receptor Potential Channel Expression in Human Fetal Midbrain-Derived Neural Progenitor Cells.

Stem cells and development, 2018, 07-15, Volume: 27, Issue:14

Voltage-gated sodium and calcium channels as well as transient receptor potential (TRP) channels are expressed during the differentiation of human neural progenitor cells (hNPCs) and are likely to be involved in regulating neurogenesis. However, the molecular composition of these ion channels in proliferating and differentiating hNPCs is largely unknown. In this study, we investigated fetal mesencephalic hNPCs in respect to their sodium, calcium, and TRP channel subunit expression and function. Quantitative real-time polymerase chain reaction indicated a significant upregulation of voltage-gated sodium and calcium channel subunits in hNPCs after differentiation for 3 weeks in vitro. In contrast, the TRP channel expression did not increase significantly during hNPC maturation. Intracellular Ca

Topics: Calcium Channels; Cell Differentiation; Cell Proliferation; Fetus; Gene Expression Regulation, Developmental; Humans; Mesencephalon; Neural Stem Cells; Pregnenolone; Stem Cells; Sulfonamides; TRPA1 Cation Channel; Voltage-Gated Sodium Channels

2018