Page last updated: 2024-08-16

rivastigmine and physostigmine

rivastigmine has been researched along with physostigmine in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (5.56)	18.2507
2000's	23 (63.89)	29.6817
2010's	6 (16.67)	24.3611
2020's	5 (13.89)	2.80

Authors

Authors	Studies
Brossi, A; Greig, NH; Holloway, HW; Whittaker, NF; Yu, QS; Zhu, X	1
Alley, GM; Brossi, A; Deschamps, JR; Greig, NH; Holloway, HW; Kulkarni, SS; Lahiri, DK; Luo, W; Parrish, D; Yu, QS; Zhan, M	1
Brossi, A; Greig, NH; Holloway, HW; Kulkarni, SS; Lahiri, DK; Luo, W; Parrish, DA; Shafferman, A; Tweedie, D; Yu, QS	1
Decker, M; Lehmann, J; Rommelspacher, H; Schott, Y	1
Carolan, CG; Dillon, GP; Gaynor, JM; Gilmer, JF; Holland, V; Jones, M; Khan, D; Marquez, JF; Reidy, S; Ryder, SA	1
Chaudhaery, SS; Nath, C; Nazir, A; Roy, KK; Sammi, SR; Saxena, AK; Saxena, G; Shakya, N	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Andrisano, V; Bartolini, M; Belluti, F; Bisi, A; Di Marzo, V; Gobbi, S; Ligresti, A; Montanari, S; Mor, M; Rampa, A; Rivara, S; Scalvini, L	1
Boddeke, H; Enz, A; Gray, J; Spiegel, R	1
Brefel-Courbon, C; Freslon, JL; Lazartigues, E; Montastruc, JL; Pelat, M; Rascol, O; Tellioglu, T; Tran, MA	1
Bejar, C; Wang, RH; Weinstock, M	1
Kosasa, T; Kuriya, Y; Ogura, H; Yamanishi, Y	1
Robert, P	1
Blount, PJ; McDeavitt, JT; Nguyen, CD	1
Tang, XC; Zhao, Q	1
Butler, R; Prabhakaran, P; Warner, J	1
Rakonczay, Z	1
Caricati-Neto, A; D'angelo, LC; Garcia, AG; Hyppolito Jurkiewicz, N; Jurkiewicz, A; Reuter, H	1
Arya, P; Butler, R; Warner, J	2
Bermudez, I; Groot-Kormelink, PJ; Smulders, CJ; van Kleef, RG; Vijverberg, HP; Zwart, R	1
Butler, R; Warner, J; Wuntakal, B	1
Aasen, I; Kumari, V; Reed, C; Sharma, T	1
Cerbai, F; Enz, A; Giovannini, MG; Melani, C; Pepeu, G	1
Dantoine, T; Debord, J; Laubarie, C	1
Kircher, T; Leucht, S; Thienel, R; Voss, B	1
Bajda, M; Malawska, B; Musiał, A	1
Barak, D; Greig, NH; Ordentlich, A; Shafferman, A; Stein, D; Yu, QS	1
Ehret, A; Feuerstein, TJ; Förster, S; Jackisch, R; Kammerer, M; Rothmaier, AK; Zentner, J	1
Edwards, CC; Hatfield, MJ; Hyatt, JL; Potter, PM; Tsurkan, LG	1
Fitzgerald, PJ; Ghimire, A; Hale, PJ; Watson, BO	1
Brown, J; Chan, BS; Downes, MA; Harris, K; Isoardi, KZ; Seebaluck, J	1
Bakkar, A; Boussi, L; Boyle, KL; Scott, M; Simpson, M; Watson, CJ; Whitledge, JD	1
Greene, SC	1
Fratta, KA; Ginder, M; Haggerty, DA	1

Reviews

9 review(s) available for rivastigmine and physostigmine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Understanding and managing behavioural symptoms in Alzheimer's disease and related dementias: focus on rivastigmine. Current medical research and opinion, 2002, Volume: 18, Issue:3 Topics: Acetylcholine; Alzheimer Disease; Carbamates; Cholinesterase Inhibitors; Cognitive Behavioral Therapy; Disease Progression; Donepezil; Galantamine; Humans; Indans; Neuroprotective Agents; Phenylcarbamates; Physostigmine; Piperidines; Rivastigmine; Tacrine; Time Factors; Treatment Outcome	2002
Clinical use of cholinomimetic agents: a review. The Journal of head trauma rehabilitation, 2002, Volume: 17, Issue:4 Topics: Administration, Oral; Adult; Aged; Alzheimer Disease; Brain Injuries; Carbamates; Clinical Trials as Topic; Cytidine Diphosphate Choline; Donepezil; Female; Follow-Up Studies; Humans; Indans; Injections, Intravenous; Injury Severity Score; Male; Middle Aged; Parasympathomimetics; Phenylcarbamates; Physostigmine; Piperidines; Rivastigmine; Severity of Illness Index; Tacrine; Treatment Outcome	2002
Dementia. Clinical evidence, 2003, Issue:9 Topics: Alzheimer Disease; Anticonvulsants; Antipsychotic Agents; Carbamates; Donepezil; Galantamine; Ginkgo biloba; Humans; Indans; Nootropic Agents; Phenylcarbamates; Phosphatidylcholines; Physostigmine; Phytotherapy; Piperidines; Rivastigmine; Tacrine; Vitamin E	2003
Dementia. Clinical evidence, 2004, Issue:11 Topics: Alzheimer Disease; Antipsychotic Agents; Benzodiazepines; Cognition; Dementia; Donepezil; Galantamine; Ginkgo biloba; Haloperidol; Humans; Indans; Memantine; Olanzapine; Phenylcarbamates; Physostigmine; Phytotherapy; Piperidines; Risperidone; Rivastigmine; Selegiline; Tacrine; Vitamin E	2004
Dementia. Clinical evidence, 2004, Issue:12 Topics: Alzheimer Disease; Dementia; Donepezil; Galantamine; Ginkgo biloba; Humans; Indans; Memantine; Nootropic Agents; Phenylcarbamates; Physostigmine; Phytotherapy; Piperidines; Rivastigmine; Tacrine	2004
Dementia. Clinical evidence, 2005, Issue:14 Topics: Alzheimer Disease; Benzodiazepines; Dementia; Donepezil; Galantamine; Ginkgo biloba; Humans; Indans; Memantine; Nootropic Agents; Olanzapine; Phenylcarbamates; Physostigmine; Phytotherapy; Piperidines; Rivastigmine; Selegiline; Tacrine	2005
[Therapy of cognitive deficits in schizophrenia with acetylcholinesterase inhibitors. A systematic overview]. Der Nervenarzt, 2008, Volume: 79, Issue:1 Topics: Antipsychotic Agents; Cholinesterase Inhibitors; Cognition Disorders; Donepezil; Galantamine; Humans; Indans; Phenylcarbamates; Physostigmine; Piperidines; Randomized Controlled Trials as Topic; Rivastigmine; Schizophrenia; Schizophrenic Psychology; Treatment Outcome	2008
Recent developments in cholinesterases inhibitors for Alzheimer's disease treatment. Current medicinal chemistry, 2007, Volume: 14, Issue:25 Topics: Alkaloids; Alzheimer Disease; Binding Sites; Cholinesterase Inhibitors; Donepezil; Galantamine; Humans; Indans; Indole Alkaloids; Isoquinolines; Phenylcarbamates; Physostigmine; Piperidines; Propidium; Rivastigmine; Steroids; Tacrine	2007

Trials

2 trial(s) available for rivastigmine and physostigmine

Article	Year
Pharmacologic and clinicopharmacologic properties of SDZ ENA 713, a centrally selective acetylcholinesterase inhibitor. Annals of the New York Academy of Sciences, 1991, Volume: 640 Topics: Alzheimer Disease; Animals; Carbamates; Cholinesterase Inhibitors; Humans; Male; Phenylcarbamates; Physostigmine; Placebos; Rats; Rivastigmine	1991
Cognitive effects of adjunctive 24-weeks Rivastigmine treatment to antipsychotics in schizophrenia: a randomized, placebo-controlled, double-blind investigation. Schizophrenia research, 2006, Volume: 85, Issue:1-3 Topics: Adult; Antipsychotic Agents; Cholinesterase Inhibitors; Cognition Disorders; Double-Blind Method; Female; Ganglionic Stimulants; Humans; Male; Middle Aged; Neuropsychological Tests; Nicotine; Phenylcarbamates; Physostigmine; Psychomotor Performance; Rivastigmine; Schizophrenia; Severity of Illness Index; Verbal Behavior	2006

Article

Year

Pharmacologic and clinicopharmacologic properties of SDZ ENA 713, a centrally selective acetylcholinesterase inhibitor.

Annals of the New York Academy of Sciences, 1991, Volume: 640

Topics: Alzheimer Disease; Animals; Carbamates; Cholinesterase Inhibitors; Humans; Male; Phenylcarbamates; Physostigmine; Placebos; Rats; Rivastigmine

1991

Cognitive effects of adjunctive 24-weeks Rivastigmine treatment to antipsychotics in schizophrenia: a randomized, placebo-controlled, double-blind investigation.

Schizophrenia research, 2006, Volume: 85, Issue:1-3

Topics: Adult; Antipsychotic Agents; Cholinesterase Inhibitors; Cognition Disorders; Double-Blind Method; Female; Ganglionic Stimulants; Humans; Male; Middle Aged; Neuropsychological Tests; Nicotine; Phenylcarbamates; Physostigmine; Psychomotor Performance; Rivastigmine; Schizophrenia; Severity of Illness Index; Verbal Behavior

2006

Other Studies

25 other study(ies) available for rivastigmine and physostigmine

Article	Year
Anticholinesterase activity of compounds related to geneserine tautomers. N-Oxides and 1,2-oxazines. Journal of medicinal chemistry, 2002, Aug-15, Volume: 45, Issue:17 Topics: Acetylcholinesterase; Alkaloids; Butyrylcholinesterase; Cholinesterase Inhibitors; Cyclic N-Oxides; Humans; Isomerism; Oxazines; Structure-Activity Relationship	2002
Novel anticholinesterases based on the molecular skeletons of furobenzofuran and methanobenzodioxepine. Journal of medicinal chemistry, 2005, Feb-24, Volume: 48, Issue:4 Topics: Acetylcholinesterase; Amyloid beta-Protein Precursor; Benzofurans; Butyrylcholinesterase; Carbamates; Cell Line; Cell Survival; Cholinesterase Inhibitors; Crystallography, X-Ray; Humans; Models, Molecular; Molecular Structure; Neurons; Oxepins; Structure-Activity Relationship	2005
Inhibition of human acetyl- and butyrylcholinesterase by novel carbamates of (-)- and (+)-tetrahydrofurobenzofuran and methanobenzodioxepine. Journal of medicinal chemistry, 2006, Apr-06, Volume: 49, Issue:7 Topics: Acetophenones; Acetylcholinesterase; Animals; Benzofurans; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Crystallography, X-Ray; Furans; Heterocyclic Compounds, 3-Ring; Humans; Models, Molecular; Oxepins; Stereoisomerism; Structure-Activity Relationship; Torpedo	2006
6-Hydroxy- and 6-methoxy-beta-carbolines as acetyl- and butyrylcholinesterase inhibitors. Bioorganic & medicinal chemistry letters, 2006, Nov-15, Volume: 16, Issue:22 Topics: Acetylcholinesterase; Alzheimer Disease; Butyrylcholinesterase; Carbolines; Cholinesterase Inhibitors; Galantamine; Humans; Inhibitory Concentration 50; Phenylcarbamates; Physostigmine; Rivastigmine; Serotonin	2006
Isosorbide-2-benzyl carbamate-5-salicylate, a peripheral anionic site binding subnanomolar selective butyrylcholinesterase inhibitor. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Anions; Binding Sites; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Humans; Inhibitory Concentration 50; Intestines; Isosorbide; Male; Microsomes, Liver; Models, Molecular; Molecular Structure; Mutation; Salicylates; Structure-Activity Relationship	2010
Novel carbamates as orally active acetylcholinesterase inhibitors found to improve scopolamine-induced cognition impairment: pharmacophore-based virtual screening, synthesis, and pharmacology. Journal of medicinal chemistry, 2010, Sep-09, Volume: 53, Issue:17 Topics: Acetylcholinesterase; Administration, Oral; Animals; Avoidance Learning; Caenorhabditis elegans; Carbamates; Catalytic Domain; Cholinesterase Inhibitors; Databases, Factual; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Male; Mice; Models, Molecular; Nootropic Agents; Quantitative Structure-Activity Relationship; Scopolamine	2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents. Journal of medicinal chemistry, 2016, 07-14, Volume: 59, Issue:13 Topics: Acetylcholinesterase; Alzheimer Disease; Amidohydrolases; Butyrylcholinesterase; Carbamates; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship	2016
Pressor and bradycardic effects of tacrine and other acetylcholinesterase inhibitors in the rat. European journal of pharmacology, 1998, Nov-13, Volume: 361, Issue:1 Topics: Adrenergic Antagonists; Animals; Antidiuretic Hormone Receptor Antagonists; Atropine; Atropine Derivatives; Blood Pressure; Carbamates; Cardiovascular Agents; Chlorisondamine; Cholinergic Antagonists; Cholinesterase Inhibitors; Diamines; Diastole; Dose-Response Relationship, Drug; Heart Rate; Male; Phenylcarbamates; Physostigmine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Rivastigmine; Systole; Tacrine	1998
Gender differences in the effect of rivastigmine on brain cholinesterase activity and cognitive function in rats. Neuropharmacology, 2000, Jan-28, Volume: 39, Issue:3 Topics: Animals; Brain; Carbamates; Cholinesterase Inhibitors; Cholinesterases; Female; Male; Memory; Memory Disorders; Muscarinic Antagonists; Muscle, Skeletal; Myocardium; Orchiectomy; Ovariectomy; Phenylcarbamates; Physostigmine; Rats; Rats, Sprague-Dawley; Rivastigmine; Scopolamine; Sex Factors	2000
Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro. Methods and findings in experimental and clinical pharmacology, 2000, Volume: 22, Issue:8 Topics: Acetylcholinesterase; Alzheimer Disease; Aminoquinolines; Animals; Benzazepines; Brain; Butyrylcholinesterase; Carbamates; Cholinesterase Inhibitors; Donepezil; In Vitro Techniques; Indans; Inhibitory Concentration 50; Male; Phenylcarbamates; Physostigmine; Piperidines; Rats; Rivastigmine; Tacrine; Time Factors	2000
Effects of huperzine A on acetylcholinesterase isoforms in vitro: comparison with tacrine, donepezil, rivastigmine and physostigmine. European journal of pharmacology, 2002, Nov-29, Volume: 455, Issue:2-3 Topics: Acetylcholinesterase; Alkaloids; Animals; Carbamates; Cerebral Cortex; Cholinesterase Inhibitors; Corpus Striatum; Donepezil; Hippocampus; Indans; Isoenzymes; Kinetics; Male; Phenylcarbamates; Physostigmine; Piperidines; Rats; Rats, Sprague-Dawley; Rivastigmine; Sesquiterpenes; Tacrine	2002
Potencies and selectivities of inhibitors of acetylcholinesterase and its molecular forms in normal and Alzheimer's disease brain. Acta biologica Hungarica, 2003, Volume: 54, Issue:2 Topics: Acetylcholinesterase; Alzheimer Disease; Benzazepines; Brain; Butyrylcholinesterase; Carbamates; Cerebral Cortex; Cholinesterase Inhibitors; Edrophonium; Humans; In Vitro Techniques; Phenylcarbamates; Physostigmine; Rivastigmine; Tacrine; Trichlorfon	2003
Enhancement of purinergic neurotransmission by galantamine and other acetylcholinesterase inhibitors in the rat vas deferens. European journal of pharmacology, 2004, Oct-25, Volume: 503, Issue:1-3 Topics: Acetylcholine; Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Donepezil; Drug Synergism; Electric Stimulation; Galantamine; In Vitro Techniques; Indans; Male; Muscle Contraction; Muscle, Smooth; Nicotine; Nicotinic Agonists; Phenylcarbamates; Physostigmine; Piperidines; Rats; Rats, Wistar; Receptors, Purinergic; Rivastigmine; Stimulation, Chemical; Synaptic Transmission; Tacrine; Vas Deferens	2004
Cholinergic drugs potentiate human nicotinic alpha4beta2 acetylcholine receptors by a competitive mechanism. European journal of pharmacology, 2005, Feb-21, Volume: 509, Issue:2-3 Topics: Acetylcholine; Alkaloids; Animals; Atropine; Azocines; Binding, Competitive; Cholinergic Agents; Cholinesterase Inhibitors; Dichlorvos; Dose-Response Relationship, Drug; Female; Galantamine; Humans; Membrane Potentials; Models, Biological; Nicotine; Oocytes; Phenylcarbamates; Physostigmine; Plasmids; Quinolizines; Receptors, Nicotinic; Rivastigmine; Scopolamine; Tacrine; Xenopus laevis	2005
N1phenethyl-norcymserine, a selective butyrylcholinesterase inhibitor, increases acetylcholine release in rat cerebral cortex: a comparison with donepezil and rivastigmine. European journal of pharmacology, 2007, Oct-31, Volume: 572, Issue:2-3 Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cerebral Cortex; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Indans; Male; Mass Spectrometry; Microdialysis; Phenylcarbamates; Physostigmine; Piperidines; Rats; Rats, Wistar; Rivastigmine	2007
Microcalorimetric study of the inhibition of butyrylcholinesterase by carbamates. Analytical biochemistry, 2008, Feb-15, Volume: 373, Issue:2 Topics: Animals; Butyrylcholinesterase; Calorimetry; Carbamates; Cholinesterase Inhibitors; Horses; Kinetics; Neostigmine; Phenylcarbamates; Physostigmine; Rivastigmine	2008
Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions. The Biochemical journal, 2009, Jan-01, Volume: 417, Issue:1 Topics: Acetylcholinesterase; Binding Sites; Catalysis; Cholinesterase Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Models, Molecular; Molecular Structure; Mutation; Phenylcarbamates; Physostigmine; Protein Binding; Pyridostigmine Bromide; Rivastigmine; Structure-Activity Relationship	2009
Inhibitory potency of choline esterase inhibitors on acetylcholine release and choline esterase activity in fresh specimens of human and rat neocortex. Journal of Alzheimer's disease : JAD, 2009, Volume: 16, Issue:3 Topics: Acetylcholine; Adolescent; Adult; Aged; Animals; Child; Child, Preschool; Cholinesterase Inhibitors; Cholinesterases; Donepezil; Galantamine; Humans; In Vitro Techniques; Indans; Middle Aged; Neocortex; Phenylcarbamates; Physostigmine; Piperidines; Rats; Rats, Wistar; Rivastigmine; Tacrine; Young Adult	2009
Inhibition of human carboxylesterases hCE1 and hiCE by cholinesterase inhibitors. Chemico-biological interactions, 2013, Mar-25, Volume: 203, Issue:1 Topics: Carboxylesterase; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Drug Interactions; Humans; Intestines; Kinetics; Liver; Models, Molecular; Phenylcarbamates; Physostigmine; Recombinant Proteins; Rivastigmine	2013
Multiple cholinesterase inhibitors have antidepressant-like properties in the mouse forced swim test. Behavioural brain research, 2021, 07-09, Volume: 409 Topics: Animals; Antidepressive Agents; Association Learning; Behavior, Animal; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Drug Repositioning; Galantamine; Male; Mice; Mice, Inbred C57BL; Motor Activity; Physostigmine; Rivastigmine; Swimming	2021
Case series profile of olanzapine post-injection delirium/sedation syndrome. British journal of clinical pharmacology, 2023, Volume: 89, Issue:2 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bromocriptine; Delirium; Female; Humans; Male; Middle Aged; Olanzapine; Physostigmine; Rivastigmine	2023
Diphenhydramine-Induced Antimuscarinic Delirium Treated with Physostigmine and Transdermal Rivastigmine. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2023, Volume: 19, Issue:2 Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Delirium; Female; Humans; Middle Aged; Muscarinic Antagonists; Physostigmine; Rivastigmine	2023
Rivastigmine Use in the Treatment of Antimuscarinic Delirium. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2023, Volume: 19, Issue:3 Topics: Cholinesterase Inhibitors; Delirium; Humans; Muscarinic Antagonists; Physostigmine; Rivastigmine	2023
Oral and Transdermal Rivastigmine for the Treatment of Anticholinergic Delirium: A Case Report. The Journal of emergency medicine, 2023, Volume: 65, Issue:4 Topics: Acetylcholinesterase; Anticholinergic Syndrome; Antidotes; Cholinergic Antagonists; Cholinesterase Inhibitors; Delirium; Female; Humans; Middle Aged; Physostigmine; Rivastigmine; Transdermal Patch	2023