rivaroxaban and osimertinib

rivaroxaban has been researched along with osimertinib* in 1 studies

Other Studies

1 other study(ies) available for rivaroxaban and osimertinib

Article	Year
Inhibition of Cytochrome P450 2J2-Mediated Metabolism of Rivaroxaban and Arachidonic Acid by Ibrutinib and Osimertinib. Drug metabolism and disposition: the biological fate of chemicals, 2022, Volume: 50, Issue:10 Covalent tyrosine kinase inhibitors (TKIs) ibrutinib and osimertinib are associated with cardiac arrhythmia. The interactions between these TKIs with CYP2J2 that is highly expressed in the human heart are unknown. In vitro metabolism experiments were performed to characterize CYP2J2-mediated metabolism of ibrutinib and osimertinib. Unbound distribution coefficient (K Topics: Acrylamides; Adenine; Aniline Compounds; Arachidonic Acid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Indoles; Piperidines; Pyrimidines; Rivaroxaban	2022

Article

Year

Inhibition of Cytochrome P450 2J2-Mediated Metabolism of Rivaroxaban and Arachidonic Acid by Ibrutinib and Osimertinib.

Drug metabolism and disposition: the biological fate of chemicals, 2022, Volume: 50, Issue:10

Covalent tyrosine kinase inhibitors (TKIs) ibrutinib and osimertinib are associated with cardiac arrhythmia. The interactions between these TKIs with CYP2J2 that is highly expressed in the human heart are unknown. In vitro metabolism experiments were performed to characterize CYP2J2-mediated metabolism of ibrutinib and osimertinib. Unbound distribution coefficient (K

Topics: Acrylamides; Adenine; Aniline Compounds; Arachidonic Acid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Indoles; Piperidines; Pyrimidines; Rivaroxaban

2022