Page last updated: 2024-08-16

ritanserin and clozapine

ritanserin has been researched along with clozapine in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's30 (56.60)18.2507
2000's17 (32.08)29.6817
2010's5 (9.43)24.3611
2020's1 (1.89)2.80

Authors

AuthorsStudies
Baldy, WJ; Barrett, DL; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Kukla, MJ; Martin, GE; Mathiasen, JR; Scott, MK1
Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP1
Abreu, ME; Bailey, MA; Ferkany, JW; Kaiser, C; Karbon, EW; Mathew, RM; Mewshaw, RE; Silverman, LS; Tiffany, CW1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR1
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR1
Boess, FG; Meyer, V; Monsma, FJ; Sleight, AJ; Zwingelstein, C1
Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB1
Bentley, J; Boess, FG; Bös, M; Bourson, A; Riemer, C; Sleight, AJ1
Boess, FG; Monsma, FJ; Sleight, AJ1
Benhamú, B; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Porras, E; Ramos, JA1
Grabtree, GW; Grailhe, R; Hen, R1
Bach, T; Krobert, KA; Kvingedal, AM; Levy, FO; Syversveen, T1
Itoh, H; Muramatsu, I; Taniguchi, T; Yoshio, R1
Glennon, RA1
Benhamú, B; Campillo, M; Lavandera, JL; López-Rodríguez, ML; Morcillo, MJ; Olivella, M; Pardo, L; Porras, E; Ramos, JA; Soto, LJ1
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D1
Andersson, CM; Brann, MR; Burstein, ES; Davis, RE; Del Tredici, AL; Gardell, LR; Geyer, MA; Harvey, SC; Lameh, J; Makhay, M; Ott, TR; Piu, F; Powell, SB; Schiffer, HH; Schlienger, N; Son, TY; Thygesen, MB; Tolf, BR; Uldam, AK; Vanover, KE; Veinbergs, I; Weiner, DM1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Ahmed, S; Harding, WW; Kapadia, N1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Abdel-Raziq, MS; Gabr, MT1
Harding, WW; Madapa, S; Namballa, HK; Sigalapalli, DK1
Marsden, CA; Rivest, R1
Porter, JH; Wiley, JL1
Cler, JA; Contreras, PC; Emmett, MR; Iyengar, S; Mick, SJ; Rao, TS; Wood, PL1
Brougham, LR; Conway, PG; Ellis, DB1
Fink, H; Morgenstern, R; Ott, T; Schremmer, C1
Hietala, J; Koulu, M; Lappalainen, J; Syvälahti, E1
Deutch, AY; Duman, RS; Ongür, D1
Arnt, J1
Fibiger, HC; Guo, N; Klitenick, MA; Tham, CS1
Andersson, JL; Iurlo, M; Kimura, K; Nomikos, GG; Svensson, TH1
Cools, AR; Ellenbroek, BA; Prinssen, EP1
Bakshi, VP; Geyer, MA; Swerdlow, NR1
Das, S; Fowler, SC1
Costall, B; Naylor, RJ1
Agren, H; Antoni, G; Fasth, KJ; Hartvig, P; Långström, B; Lindström, L; Lundberg, T; Lundqvist, H; Reibring, L1
Dudley, MW; Kehne, JH; Ketteler, HJ; McCloskey, TC; Schmidt, CJ; Sullivan, CK1
Szczepanik, AM; Wilmot, CA1
Depoortere, R; Perrault, G; Sanger, DJ1
Cardwell, GP; Hicks, CA; O'Neill, MF; O'Neill, MJ; Parameswaran, T; Shaw, G1
Bergqvist, PB; Blier, P; Dong, J1
Alsayegh, L; Backstrom, JR; Berry, SA; Friedman, L; Roth, BL; Sanders-Bush, E; Willins, DL1
McCallum, SE; Porter, JH; Vann, RE; Varvel, SA1
Gaisler, I; Schiller, D; Shadach, E; Weiner, I1
Gessa, GL; Marchese, G; Pani, L; Ruiu, S; Saba, PL1
Ashe, P; Chlan-Fourney, J; Juorio, AV; Li, XM; Nylen, K1
Inoue, T; Itoh, S; Morimoto, T; Ogawa, S; Saito, M; Wakisaka, S1
Feuerbach, D; Loetscher, E; Mahé, C; Müller, W; Schoeffter, P; Seiler, MP1
D'Aquila, PS; Franconi, F; Galistu, A; Modde, C; Pireddu, MC; Serra, G1
Barbosa Silva, RC; de Oliveira, RP; Nagaishi, KY1

Reviews

2 review(s) available for ritanserin and clozapine

ArticleYear
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003
Semisynthetic Transformations on (+)-Boldine Reveal a 5-HT
    Journal of natural products, 2022, 09-23, Volume: 85, Issue:9

    Topics: Aporphines; Caco-2 Cells; Humans; Ligands; Serotonin 5-HT2 Receptor Antagonists

2022

Other Studies

51 other study(ies) available for ritanserin and clozapine

ArticleYear
Pyrrole mannich bases as potential antipsychotic agents.
    Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Male; Mannich Bases; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship

1992
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

1993
Examination of the D2/5-HT2 affinity ratios of resolved 5,6,7,8,9,10-hexahydro-7,10-iminocyclohept[b]indoles: an enantioselective approach toward the design of potential atypical antipsychotics.
    Journal of medicinal chemistry, 1993, Oct-15, Volume: 36, Issue:21

    Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Drug Design; Indoles; Receptors, Dopamine D2; Receptors, Serotonin; Stereoisomerism

1993
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
    The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection

1993
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
    Journal of neurochemistry, 1996, Volume: 66, Issue:1

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity

1996
Interaction of tryptamine and ergoline compounds with threonine 196 in the ligand binding site of the 5-hydroxytryptamine6 receptor.
    Molecular pharmacology, 1997, Volume: 52, Issue:3

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Cloning, Molecular; Cricetinae; Dogs; Drug Interactions; Ergolines; Guinea Pigs; Humans; Kidney; Ligands; Lysergic Acid Diethylamide; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Rats; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin; Threonine; Tryptamines

1997
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1

    Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine

1998
The 5-hydroxytryptamine6 receptor-selective radioligand [3H]Ro 63-0563 labels 5-hydroxytryptamine receptor binding sites in rat and porcine striatum.
    Molecular pharmacology, 1998, Volume: 54, Issue:3

    Topics: Aminopyridines; Animals; Binding Sites; Corpus Striatum; HeLa Cells; Humans; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin Antagonists; Species Specificity; Swine; Tritium

1998
Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor.
    Journal of neurochemistry, 1998, Volume: 71, Issue:5

    Topics: Adenylyl Cyclases; Amino Acid Substitution; Binding Sites; Binding, Competitive; Cell Line; Cyclic AMP; Humans; Ligands; Lysergic Acid Diethylamide; Mutagenesis, Site-Directed; Mutation; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists

1998
First pharmacophoric hypothesis for 5-HT7 antagonism.
    Bioorganic & medicinal chemistry letters, 2000, May-15, Volume: 10, Issue:10

    Topics: Animals; Cell Membrane; Drug Design; Drug Evaluation, Preclinical; Hypothalamus; Models, Molecular; Rats; Receptors, Serotonin; Reproducibility of Results; Serotonin Antagonists; Structure-Activity Relationship

2000
Human 5-HT(5) receptors: the 5-HT(5A) receptor is functional but the 5-HT(5B) receptor was lost during mammalian evolution.
    European journal of pharmacology, 2001, Apr-27, Volume: 418, Issue:3

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; COS Cells; DNA; Evolution, Molecular; Gene Expression; Genes; Humans; Membranes; Mice; Molecular Sequence Data; Phylogeny; Radioligand Assay; Receptors, Serotonin; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid

2001
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:6

    Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Brain; Cell Line; Cloning, Organism; Genetic Variation; Humans; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution

2001
Affinity of serotonin receptor antagonists and agonists to recombinant and native alpha1-adrenoceptor subtypes.
    Japanese journal of pharmacology, 2001, Volume: 86, Issue:2

    Topics: Animals; Aorta, Thoracic; Carotid Arteries; Dogs; Humans; Male; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists

2001
Optimization of the pharmacophore model for 5-HT7R antagonism. Design and synthesis of new naphtholactam and naphthosultam derivatives.
    Journal of medicinal chemistry, 2003, Dec-18, Volume: 46, Issue:26

    Topics: Animals; Binding, Competitive; Computer Simulation; Drug Design; Hypothalamus; In Vitro Techniques; Lactams; Ligands; Male; Models, Molecular; Molecular Conformation; Naphthalenes; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides; Thiazoles

2003
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2

    Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2004
Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 317, Issue:2

    Topics: Animals; Behavior, Animal; Biological Availability; Cloning, Molecular; Humans; Male; Mice; NIH 3T3 Cells; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Urea

2006
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
New halogenated tris-(phenylalkyl)amines as h5-HT2B receptor ligands.
    Bioorganic & medicinal chemistry letters, 2016, 07-15, Volume: 26, Issue:14

    Topics: Amines; Dose-Response Relationship, Drug; Humans; Ligands; Molecular Structure; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Structure-Activity Relationship

2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Pharmacophore-based tailoring of biphenyl amide derivatives as selective 5-hydroxytryptamine 2B receptor antagonists.
    MedChemComm, 2018, Jun-01, Volume: 9, Issue:6

    Topics:

2018
Differential effects of amfonelic acid on the haloperidol- and clozapine-induced increase in extracellular DOPAC in the nucleus accumbens and the striatum.
    Synapse (New York, N.Y.), 1992, Volume: 10, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clozapine; Corpus Striatum; Drug Interactions; Haloperidol; Hydroxyindoleacetic Acid; Kinetics; Male; Membrane Potentials; Nalidixic Acid; Naphthyridines; Nucleus Accumbens; Rats; Rats, Inbred Strains; Ritanserin; Time Factors

1992
Serotonergic drugs do not substitute for clozapine in clozapine-trained rats in a two-lever drug discrimination procedure.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:3

    Topics: Animals; Buspirone; Clozapine; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Psychological; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes

1992
Clozapine attenuates N-methyl-D-aspartate receptor complex-mediated responses in vivo: tentative evidence for a functional modulation by a noradrenergic mechanism.
    Neuropharmacology, 1991, Volume: 30, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Cerebellum; Clozapine; Cyclic GMP; Dioxanes; Haloperidol; Harmaline; Histamine H2 Antagonists; In Vitro Techniques; Indoles; Injections, Intraventricular; Male; Methamphetamine; Mice; Norepinephrine; Pentylenetetrazole; Receptors, N-Methyl-D-Aspartate; Ritanserin; Serine; Tropisetron

1991
Effect of ritanserin on the interaction of amfonelic acid and neuroleptic-induced striatal dopamine metabolism.
    Neuropharmacology, 1991, Volume: 30, Issue:10

    Topics: Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; Clozapine; Corpus Striatum; Dopamine; Haloperidol; Male; Nalidixic Acid; Naphthyridines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin Antagonists; Substantia Nigra; Synaptic Transmission

1991
Atypical neuroleptics suppress dopaminergic behavioral supersensitivity.
    Psychopharmacology, 1990, Volume: 100, Issue:3

    Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Clozapine; Cyproheptadine; Haloperidol; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Ritanserin; Serotonin Antagonists; Sulpiride; Thioridazine

1990
Neurochemical effects of chronic co-administration of ritanserin and haloperidol: comparison with clozapine effects.
    European journal of pharmacology, 1990, Nov-13, Volume: 190, Issue:3

    Topics: Animals; Clozapine; Dopamine; Drug Combinations; Haloperidol; Male; Nucleus Accumbens; Piperidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin; Substantia Nigra; Time Factors

1990
Antipsychotic drugs induce Fos protein in the thalamic paraventricular nucleus: a novel locus of antipsychotic drug action.
    Neuroscience, 1995, Volume: 66, Issue:2

    Topics: Animals; Antipsychotic Agents; Blotting, Western; Clozapine; Haloperidol; Immunohistochemistry; Male; Muscarinic Antagonists; Prazosin; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Ritanserin; Scopolamine; Serotonin Antagonists; Sulpiride; Thalamic Nuclei

1995
Differential effects of classical and newer antipsychotics on the hypermotility induced by two dose levels of D-amphetamine.
    European journal of pharmacology, 1995, Sep-05, Volume: 283, Issue:1-3

    Topics: Animals; Antipsychotic Agents; Clozapine; Dextroamphetamine; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Imidazoles; Indoles; Locomotion; Male; Motor Activity; Prazosin; Rats; Rats, Wistar; Ritanserin

1995
Receptor mechanisms mediating clozapine-induced c-fos expression in the forebrain.
    Neuroscience, 1995, Volume: 65, Issue:3

    Topics: Animals; Clozapine; Dopamine; Immunohistochemistry; Male; Norepinephrine; Prosencephalon; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Dopamine; Ritanserin; Serotonin

1995
Systemic administration of amperozide, a new atypical antipsychotic drug, preferentially increases dopamine release in the rat medial prefrontal cortex.
    Psychopharmacology, 1994, Volume: 115, Issue:1-2

    Topics: Animals; Antipsychotic Agents; Clozapine; Dopamine; Male; Microdialysis; Neostriatum; Nucleus Accumbens; Piperazines; Prefrontal Cortex; Rats; Rats, Wistar; Ritanserin; Serotonin Antagonists; Synaptic Transmission

1994
The role of serotonin receptor subtypes in the behavioural effects of neuroleptic drugs. A paw test study in rats.
    The European journal of neuroscience, 1994, Jan-01, Volume: 6, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Behavior, Animal; Clozapine; Haloperidol; Ketanserin; Male; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists

1994
Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2

    Topics: Acoustic Stimulation; Animals; Benzazepines; Clozapine; Dizocilpine Maleate; Ketanserin; Male; Phencyclidine; Raclopride; Rats; Rats, Sprague-Dawley; Reflex, Startle; Ritanserin; Salicylamides

1994
Acute and subchronic effects of clozapine on licking in rats: tolerance to disruptive effects on number of licks, but no tolerance to rhythm slowing.
    Psychopharmacology, 1995, Volume: 120, Issue:3

    Topics: Animals; Clozapine; Conditioning, Operant; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Ritanserin; Time Factors; Tongue

1995
Behavioural interactions between 5-hydroxytryptophan, neuroleptic agents and 5-HT receptor antagonists in modifying rodent responding to aversive situations.
    British journal of pharmacology, 1995, Volume: 116, Issue:7

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Benperidol; Clozapine; Drug Interactions; Haloperidol; Male; Mice; Mice, Inbred Strains; Rats; Rats, Inbred Strains; Ritanserin; Serotonin; Serotonin Antagonists; Social Behavior; Sulpiride; Thioridazine

1995
Serotonin-2 and dopamine-1 binding components of clozapine in frontal cortex and striatum in the human brain visualized by positron emission tomography.
    Psychiatry research, 1996, May-31, Volume: 67, Issue:1

    Topics: Adult; Binding Sites; Clozapine; Corpus Striatum; Dopamine; Dopamine Antagonists; Drug Synergism; Female; Flupenthixol; Frontal Lobe; Humans; Male; Ritanserin; Serotonin; Serotonin Antagonists; Tomography, Emission-Computed

1996
Effects of the selective 5-HT2A receptor antagonist MDL 100,907 on MDMA-induced locomotor stimulation in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1996, Volume: 15, Issue:2

    Topics: 5,7-Dihydroxytryptamine; Animals; Brain Chemistry; Clozapine; Dopamine Antagonists; Fluorobenzenes; Male; Methiothepin; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Presynaptic Terminals; Rats; Receptors, Neurotransmitter; Ritanserin; Serotonin; Serotonin Agents; Serotonin Antagonists; Stimulation, Chemical

1996
Effects of ritanserin on haloperidol-induced dopamine (D2) receptor up-regulation in the rat.
    Neuroscience letters, 1997, Aug-08, Volume: 231, Issue:2

    Topics: Animals; Antipsychotic Agents; Autoradiography; Cerebral Cortex; Clozapine; Corpus Striatum; Dopamine Antagonists; Haloperidol; Image Processing, Computer-Assisted; Male; Nucleus Accumbens; Quinolines; Rats; Rats, Wistar; Receptors, Dopamine D2; Ritanserin; Serotonin Antagonists; Up-Regulation

1997
Some, but not all, antipsychotic drugs potentiate a low level of prepulse inhibition shown by rats of the Wistar strain.
    Behavioural pharmacology, 1997, Volume: 8, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Benzodiazepines; Clozapine; Haloperidol; Imidazoles; Indoles; Injections, Intraperitoneal; Male; Neural Inhibition; Olanzapine; Pirenzepine; Prazosin; Rats; Rats, Wistar; Reflex, Startle; Remoxipride; Risperidone; Ritanserin; Serotonin Antagonists

1997
Effects of 5-hydroxytryptamine2 receptor antagonism on the behavioral activation and immediate early gene expression induced by dizocilpine.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:3

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Gyrus Cinguli; Haloperidol; HSP70 Heat-Shock Proteins; Immediate-Early Proteins; Immunohistochemistry; Ketanserin; Mice; Motor Activity; Proto-Oncogene Proteins c-fos; Ritanserin; Serotonin Antagonists

1998
Effect of atypical antipsychotic drugs on 5-HT2 receptors in the rat orbito-frontal cortex: an in vivo electrophysiological study.
    Psychopharmacology, 1999, Volume: 143, Issue:1

    Topics: Amphetamines; Animals; Antipsychotic Agents; Bicuculline; Clozapine; Electrophysiology; GABA Antagonists; Iontophoresis; Male; Neurons; Piperazines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, GABA-A; Receptors, Serotonin; Risperidone; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists

1999
Clozapine and other 5-hydroxytryptamine-2A receptor antagonists alter the subcellular distribution of 5-hydroxytryptamine-2A receptors in vitro and in vivo.
    Neuroscience, 1999, Volume: 91, Issue:2

    Topics: 3T3 Cells; Animals; Antipsychotic Agents; Benzodiazepines; Cell Line; Clozapine; Dendrites; Fluorobenzenes; Haloperidol; Mianserin; Mice; Olanzapine; Piperidines; Pirenzepine; Prefrontal Cortex; Pyramidal Cells; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Recombinant Proteins; Risperidone; Ritanserin; Serotonin Antagonists; Transfection

1999
The discriminative stimulus properties of the atypical antipsychotic olanzapine in rats.
    Psychopharmacology, 2000, Volume: 148, Issue:3

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Discrimination Learning; Generalization, Psychological; Haloperidol; Male; Olanzapine; Pirenzepine; Raclopride; Rats; Rats, Sprague-Dawley; Risperidone; Ritanserin; Scopolamine

2000
The latent inhibition model dissociates between clozapine, haloperidol, and ritanserin.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 23, Issue:2

    Topics: Acoustic Stimulation; Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Conditioning, Psychological; Drinking Behavior; Electric Stimulation; Haloperidol; Male; Rats; Rats, Wistar; Ritanserin

2000
The 5-HT2 antagonist ritanserin blocks dopamine re-uptake in the rat frontal cortex.
    Molecular psychiatry, 2000, Volume: 5, Issue:6

    Topics: Animals; Clozapine; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Frontal Lobe; Haloperidol; Ketanserin; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Risperidone; Ritanserin; Serotonin Antagonists; Synaptosomes; Tritium

2000
Differential regulation of hippocampal BDNF mRNA by typical and atypical antipsychotic administration.
    Brain research, 2002, Nov-01, Volume: 954, Issue:1

    Topics: Animals; Antipsychotic Agents; Blotting, Northern; Brain-Derived Neurotrophic Factor; Clozapine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation; Haloperidol; Hippocampus; In Situ Hybridization; Male; Rats; Rats, Wistar; Remoxipride; Risperidone; Ritanserin; RNA, Messenger; Time Factors

2002
Involvement of 5-HT7 receptors in serotonergic effects on spike afterpotentials in presumed jaw-closing motoneurons of rats.
    Brain research, 2002, Nov-08, Volume: 954, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Alkaloids; Animals; Benzophenanthridines; Brain Stem; Calcium; Clozapine; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Enzyme Inhibitors; Isoquinolines; Jaw; Membrane Potentials; Motor Neurons; Phenanthridines; Pindolol; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides

2002
Differential inverse agonist efficacies of SB-258719, SB-258741 and SB-269970 at human recombinant serotonin 5-HT7 receptors.
    European journal of pharmacology, 2004, Jul-14, Volume: 495, Issue:2-3

    Topics: Animals; Binding, Competitive; CHO Cells; Clozapine; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Ergolines; Humans; Loxapine; Methiothepin; Phenols; Pimozide; Pindolol; Piperidines; Plasmids; Pyrrolidines; Radioligand Assay; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tosyl Compounds; Transfection

2004
Clozapine increases reward evaluation but not overall ingestive behaviour in rats licking for sucrose.
    Psychopharmacology, 2011, Volume: 216, Issue:3

    Topics: Anhedonia; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Data Interpretation, Statistical; Dopamine Antagonists; Feeding Behavior; Haloperidol; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Reward; Ritanserin; Serotonin Antagonists; Sucrose

2011
Atypical antipsychotic clozapine reversed deficit on prepulse inhibition of the acoustic startle reflex produced by microinjection of DOI into the inferior colliculus in rats.
    Behavioural brain research, 2017, 05-15, Volume: 325, Issue:Pt A

    Topics: Amphetamines; Animals; Antipsychotic Agents; Clozapine; Inferior Colliculi; Male; Microinjections; Prepulse Inhibition; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Ritanserin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists

2017