Page last updated: 2024-08-16

risperidone and norclozapine

risperidone has been researched along with norclozapine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's5 (31.25)29.6817
2010's10 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keserü, GM1
Jia, L; Sun, H1
Giordanetto, F; Leach, AG; Zachariae, U1
Sen, S; Sinha, N1
Cremers, TI; Flik, G; Hofland, C; Stratford, RE1
Doran, AC; Mancuso, JY; Osgood, SM; Shaffer, CL1
Dalvie, D; Loi, CM; Smith, DA1
Bellman, K; Knegtel, RM; Settimo, L1
Freeman, DJ; Li, MC; Oyewumi, K1
Axelsson, S; Eriksson, AC; Hägg, S; Lindahl, TL; Whiss, PA1
Dai, J; Li, Z; Meltzer, HY; Roseman, AS; Snigdha, S1
Gründer, G; Orfanos, S; Paulzen, M1
Couchman, L; Fisher, DS; Flanagan, RJ; Handley, SA; Morgan, PE; Partridge, SJ1
Fisher, DS; Flanagan, RJ; Handley, SA; Partridge, SJ1
Deckert, J; Hommers, LG; Menke, A; Samanski, L; Scherf-Clavel, M; Unterecker, S1
Centanni, M; de Lange, ECM; Wong, YC1

Trials

1 trial(s) available for risperidone and norclozapine

ArticleYear
Solid-phase extraction and high-performance liquid chromatographic analysis of clozapine and norclozapine in human plasma.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:6

    Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Clozapine; Drug Interactions; Drug Monitoring; Humans; Risperidone; Verapamil

1996

Other Studies

15 other study(ies) available for risperidone and norclozapine

ArticleYear
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.
    Journal of medicinal chemistry, 2009, Jul-23, Volume: 52, Issue:14

    Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation

2009
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Microdialysis evaluation of clozapine and N-desmethylclozapine pharmacokinetics in rat brain.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:10

    Topics: Animals; Antipsychotic Agents; Biotransformation; Blood-Brain Barrier; Brain; Clozapine; Injections, Subcutaneous; Male; Microdialysis; Models, Biological; Permeability; Rats; Rats, Wistar

2012
An evaluation of using rat-derived single-dose neuropharmacokinetic parameters to project accurately large animal unbound brain drug concentrations.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:11

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Brain Chemistry; Dogs; Isoxazoles; Male; Paliperidone Palmitate; Primates; Pyrimidines; Rats; Rats, Sprague-Dawley; Risperidone; Thiophenes

2012
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
In vitro effects of antipsychotics on human platelet adhesion and aggregation and plasma coagulation.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:8

    Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Blood Coagulation; Blood Platelets; Clozapine; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; In Vitro Techniques; Male; Middle Aged; Olanzapine; Partial Thromboplastin Time; Platelet Adhesiveness; Platelet Aggregation; Prothrombin Time; Risperidone; Thromboembolism; Venous Thrombosis

2007
Effect of muscarinic receptor agonists xanomeline and sabcomeline on acetylcholine and dopamine efflux in the rat brain; comparison with effects of 4-[3-(4-butylpiperidin-1-yl)-propyl]-7-fluoro-4H-benzo[1,4]oxazin-3-one (AC260584) and N-desmethylclozapine
    European journal of pharmacology, 2008, Oct-31, Volume: 596, Issue:1-3

    Topics: Acetylcholine; Animals; Antipsychotic Agents; Benzoxazines; Brain; Clozapine; Dopamine; Drug Synergism; Imines; Male; Nucleus Accumbens; Pirenzepine; Prefrontal Cortex; Pyridines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptor, Muscarinic M4; Risperidone; Thiadiazoles

2008
Remission of drug-induced hepatitis after switching from risperidone to paliperidone.
    The American journal of psychiatry, 2010, Volume: 167, Issue:3

    Topics: Adult; Antipsychotic Agents; Biotransformation; Chemical and Drug Induced Liver Injury; Clozapine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Isoxazoles; Liver Function Tests; Paliperidone Palmitate; Pyrimidines; Reference Values; Risperidone; Schizophrenia

2010
LC-MS/MS of some atypical antipsychotics in human plasma, serum, oral fluid and haemolysed whole blood.
    Forensic science international, 2013, Jun-10, Volume: 229, Issue:1-3

    Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chromatography, Liquid; Clozapine; Dibenzothiazepines; Female; Forensic Toxicology; Hemolysis; Humans; Isoxazoles; Male; Olanzapine; Paliperidone Palmitate; Piperazines; Pyrimidines; Quetiapine Fumarate; Quinolones; Reproducibility of Results; Risperidone; Saliva; Serum; Sulpiride; Tandem Mass Spectrometry

2013
Stability of some atypical antipsychotics in human plasma, haemolysed whole blood, oral fluid, human serum and calf serum.
    Forensic science international, 2013, Jun-10, Volume: 229, Issue:1-3

    Topics: Amisulpride; Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Cattle; Chromatography, Liquid; Clozapine; Dibenzothiazepines; Drug Stability; Female; Forensic Toxicology; Hemolysis; Humans; Isoxazoles; Male; Olanzapine; Paliperidone Palmitate; Piperazines; Pyrimidines; Quetiapine Fumarate; Quinolones; Reproducibility of Results; Risperidone; Saliva; Serum; Sulpiride; Tandem Mass Spectrometry

2013
Analysis of smoking behavior on the pharmacokinetics of antidepressants and antipsychotics: evidence for the role of alternative pathways apart from CYP1A2.
    International clinical psychopharmacology, 2019, Volume: 34, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Clozapine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Desvenlafaxine Succinate; Doxepin; Drug Monitoring; Female; Glucuronosyltransferase; Humans; Male; Middle Aged; Mirtazapine; Nortriptyline; Paliperidone Palmitate; Quetiapine Fumarate; Retrospective Studies; Risperidone; Smoking; Venlafaxine Hydrochloride

2019
Physiologically Based Modeling Approach to Predict Dopamine D2 Receptor Occupancy of Antipsychotics in Brain: Translation From Rat to Human.
    Journal of clinical pharmacology, 2019, Volume: 59, Issue:5

    Topics: Animals; Antipsychotic Agents; Brain; Clozapine; Dopamine D2 Receptor Antagonists; Female; Humans; Kinetics; Male; Models, Biological; Paliperidone Palmitate; Rats; Receptors, Dopamine D2; Risperidone; Translational Research, Biomedical

2019