Page last updated: 2024-08-16

risperidone and mdl 100907

risperidone has been researched along with mdl 100907 in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (13.33)18.2507
2000's13 (43.33)29.6817
2010's11 (36.67)24.3611
2020's2 (6.67)2.80

Authors

AuthorsStudies
Bristow, LJ; Hutson, PH; Rowley, M1
Bonaventure, P; Carruthers, NI; Dvorak, CA; Dvorak, L; Lovenberg, TW; Miller, KL; Nepomuceno, D; Rudolph, DA; Shireman, BT1
Giordanetto, F; Leach, AG; Zachariae, U1
Brocco, M; Millan, MJ; Schreiber, R1
Fischer, TR; Hitchcock, JM; Lister, S; Wettstein, JG1
Bakshi, VP; Geyer, MA; Varty, GB1
Alsayegh, L; Backstrom, JR; Berry, SA; Friedman, L; Roth, BL; Sanders-Bush, E; Willins, DL1
Ichikawa, J; Meltzer, HY1
Carlsson, A; Carlsson, ML; Nilsson, M; Waters, N; Waters, S1
Honkanen, A; Huttunen, MO; Hyytiä, P; Ingman, K; Korpi, ER1
Ikeda, M; Iwata, N; Kitajima, T; Ozaki, N; Suzuki, T; Yamanouchi, Y1
Alevizos, B; Christodoulou, GN; Lykouras, L; Zervas, IM1
De La Garza, R; Kalechstein, AD; Newton, TF1
Jeong, JH; Kang, MS; Kim, DM; Kim, JS1
Altschuler, EL; Focosi, D; Kast, RE; Petrini, M1
Diamant, L; Gaisler-Salomon, I; Rubin, C; Weiner, I1
Arnt, J; Mørk, A; Witten, LM1
Choi, YK; Gardner, MP; Moran-Gates, T; Tarazi, FI1
Adams, W; van den Buuse, M1
Craig, F; Margari, F; Margari, L; Matera, E; Palmieri, VO; Pastore, A; Petruzzelli, MG1
Fijał, K; Nikiforuk, A; Popik, P1
Amodeo, DA; Jones, JH; Ragozzino, ME; Sweeney, JA1
Chuluun, B; Colas, D; Das, D; Garner, CC; Heller, HC; Lin, B; Moghadam, S; Salehi, A1
Guo, Y; Hu, L; Liu, C; Luo, B; Wang, H1
Baki, L; Drossopoulos, P; Dukat, M; Ellaithy, A; Eltit, JM; Gaitonde, SA; Glennon, RA; González-Maeso, J; Hideshima, KS; Logothetis, DE; Moreno, JL; Shah, S; Vekariya, R; Younkin, J1
Gu, F; Ma, W; Meng, G; Wang, Y; Wu, C1
He, Y; Jiang, H; Jiang, X; Li, J; Liu, Y; Shen, J; Tian, G; Wang, Y; Wang, Z; Wu, C; Xu, M; Yang, F; Ye, B; Zhang, J; Zhao, Q1
Alemany-González, M; Chanovas, J; Delgado-Sallent, C; Gener, T; Nebot, P; Puig, MV; Tauste Campo, A1
Makiguchi, A; Okada, T; Shioda, K; Suda, S1
Basu, B; John Jayakumar, JAK; Panicker, MM1

Reviews

1 review(s) available for risperidone and mdl 100907

ArticleYear
Current and novel approaches to the drug treatment of schizophrenia.
    Journal of medicinal chemistry, 2001, Feb-15, Volume: 44, Issue:4

    Topics: Animals; Antipsychotic Agents; Cholinergic Agonists; Disease Models, Animal; Dopamine Antagonists; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Mice; Mice, Transgenic; Nitric Oxide Synthase; Receptor, Serotonin, 5-HT2A; Receptors, AMPA; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotensin; Receptors, Serotonin; Schizophrenia; Serotonin Antagonists

2001

Trials

1 trial(s) available for risperidone and mdl 100907

ArticleYear
Risperidone diminishes cocaine-induced craving.
    Psychopharmacology, 2005, Volume: 178, Issue:2-3

    Topics: Adult; Antipsychotic Agents; Cocaine-Related Disorders; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Motivation; Premedication; Risperidone; Serotonin 5-HT2 Receptor Antagonists; Substance Abuse, Intravenous

2005

Other Studies

28 other study(ies) available for risperidone and mdl 100907

ArticleYear
2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists.
    Bioorganic & medicinal chemistry letters, 2008, Mar-15, Volume: 18, Issue:6

    Topics: Animals; Azepines; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Humans; Mice; Molecular Structure; NIH 3T3 Cells; Pyrimidines; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Structure-Activity Relationship

2008
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.
    Journal of medicinal chemistry, 2009, Jul-23, Volume: 52, Issue:14

    Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation

2009
Blockade of the discriminative stimulus effects of DOI by MDL 100,907 and the 'atypical' antipsychotics, clozapine and risperidone.
    European journal of pharmacology, 1994, Oct-13, Volume: 264, Issue:1

    Topics: Amphetamines; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Fluorobenzenes; Isoxazoles; Male; Motor Activity; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Risperidone; Serotonin Antagonists

1994
Disruption of latent inhibition in the rat by the 5-HT2 agonist DOI: effects of MDL 100,907, clozapine, risperidone and haloperidol.
    Behavioural brain research, 1997, Volume: 88, Issue:1

    Topics: Amphetamines; Animals; Antipsychotic Agents; Clozapine; Conditioning, Operant; Fluorobenzenes; Haloperidol; Male; Piperidines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Reinforcement, Psychology; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists

1997
M100907, a serotonin 5-HT2A receptor antagonist and putative antipsychotic, blocks dizocilpine-induced prepulse inhibition deficits in Sprague-Dawley and Wistar rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 20, Issue:4

    Topics: Animals; Antipsychotic Agents; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fluorobenzenes; Male; Piperidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reflex, Startle; Risperidone; Serotonin Antagonists; Species Specificity

1999
Clozapine and other 5-hydroxytryptamine-2A receptor antagonists alter the subcellular distribution of 5-hydroxytryptamine-2A receptors in vitro and in vivo.
    Neuroscience, 1999, Volume: 91, Issue:2

    Topics: 3T3 Cells; Animals; Antipsychotic Agents; Benzodiazepines; Cell Line; Clozapine; Dendrites; Fluorobenzenes; Haloperidol; Mianserin; Mice; Olanzapine; Piperidines; Pirenzepine; Prefrontal Cortex; Pyramidal Cells; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Recombinant Proteins; Risperidone; Ritanserin; Serotonin Antagonists; Transfection

1999
The effect of serotonin(1A) receptor agonism on antipsychotic drug-induced dopamine release in rat striatum and nucleus accumbens.
    Brain research, 2000, Mar-10, Volume: 858, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Clozapine; Corpus Striatum; Dopamine; Fluorobenzenes; Haloperidol; Male; Microdialysis; Nucleus Accumbens; Piperazines; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Risperidone; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium

2000
A behavioural pattern analysis of hypoglutamatergic mice--effects of four different antipsychotic agents.
    Journal of neural transmission (Vienna, Austria : 1996), 2001, Volume: 108, Issue:10

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Dizocilpine Maleate; Dopamine Antagonists; Drug Combinations; Excitatory Amino Acid Antagonists; Fluorobenzenes; Glutamic Acid; Haloperidol; Injections, Intraperitoneal; Male; Mice; Motor Activity; Piperidines; Risperidone; Serotonin Antagonists

2001
Risperidone reduces limited access alcohol drinking in alcohol-preferring rats.
    European journal of pharmacology, 2003, May-09, Volume: 468, Issue:2

    Topics: Alcohol Drinking; Alcoholism; Animals; Antipsychotic Agents; Disease Models, Animal; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Male; Motor Activity; Rats; Risperidone; Saccharin; Self Administration; Serotonin 5-HT2 Receptor Antagonists

2003
Effect of DRD2, 5-HT2A, and COMT genes on antipsychotic response to risperidone.
    The pharmacogenomics journal, 2003, Volume: 3, Issue:6

    Topics: Adult; Antipsychotic Agents; Catechol O-Methyltransferase; Chi-Square Distribution; Dopamine D2 Receptor Antagonists; Female; Humans; Male; Middle Aged; Polymorphism, Genetic; Psychotic Disorders; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Risperidone; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists; Statistics, Nonparametric

2003
Reply to "Risperidone-induced obsessive-compulsive symptoms: serotonin-dopamine imbalance?".
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:5

    Topics: Antipsychotic Agents; Brain; Dopamine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Long-Term Care; Obsessive-Compulsive Disorder; Risk Factors; Risperidone; Serotonin; Serotonin 5-HT2 Receptor Antagonists

2004
An efficient synthesis of risperidone via stille reaction: antipsychotic, 5-HT2, and dopamine-D2-antagonist.
    Archives of pharmacal research, 2005, Volume: 28, Issue:9

    Topics: Antipsychotic Agents; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Risperidone; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists

2005
Treatment schedules for 5-HT2A blocking in progressive multifocal leukoencephalopathy using risperidone or ziprasidone.
    Bone marrow transplantation, 2007, Volume: 39, Issue:12

    Topics: Adult; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Piperazines; Risperidone; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Thiazoles

2007
Abnormally persistent latent inhibition induced by MK801 is reversed by risperidone and by positive modulators of NMDA receptor function: differential efficacy depending on the stage of the task at which they are administered.
    Psychopharmacology, 2008, Volume: 196, Issue:2

    Topics: Animals; Behavior, Animal; Clozapine; Conditioning, Psychological; Cycloserine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Emotions; Fluorobenzenes; Glycine; Glycine Agents; Inhibition, Psychological; Male; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Stress, Psychological; Thirst; Treatment Outcome

2008
Effect of sertindole on extracellular dopamine, acetylcholine, and glutamate in the medial prefrontal cortex of conscious rats: a comparison with risperidone and exploration of mechanisms involved.
    Psychopharmacology, 2009, Volume: 206, Issue:1

    Topics: Acetylcholine; Animals; Antipsychotic Agents; Dopamine; Dopamine D2 Receptor Antagonists; Drug Synergism; Extracellular Space; Fluorobenzenes; Glutamic Acid; Haloperidol; Imidazoles; Indoles; Male; Microdialysis; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin 5-HT2 Receptor Antagonists

2009
Effects of repeated risperidone exposure on serotonin receptor subtypes in developing rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010, Volume: 20, Issue:3

    Topics: Age Factors; Animals; Animals, Newborn; Brain; Dose-Response Relationship, Drug; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Risperidone; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists

2010
Hippocampal serotonin depletion facilitates the enhancement of prepulse inhibition by risperidone: possible role of 5-HT(2C) receptors in the dorsal hippocampus.
    Neuropharmacology, 2011, Volume: 61, Issue:3

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Ergolines; Hippocampus; Male; Nerve Tissue Proteins; Neural Inhibition; Neurons; Organ Specificity; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Reflex, Startle; Risperidone; Schizophrenia; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists

2011
Tolerability and safety profile of risperidone in a sample of children and adolescents.
    International clinical psychopharmacology, 2013, Volume: 28, Issue:4

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Body Composition; Body Mass Index; Child; Child Development Disorders, Pervasive; Diagnostic and Statistical Manual of Mental Disorders; Dopamine Antagonists; Drug Monitoring; Female; Follow-Up Studies; Humans; Male; Prolactin; Risperidone; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists; Tic Disorders; Up-Regulation; Weight Gain

2013
Co-administration of 5-HT6 receptor antagonists with clozapine, risperidone, and a 5-HT2A receptor antagonist: effects on prepulse inhibition in rats.
    Psychopharmacology, 2014, Volume: 231, Issue:1

    Topics: Animals; Antipsychotic Agents; Clozapine; Data Interpretation, Statistical; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Haloperidol; Male; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reflex, Startle; Risperidone; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Sulfonamides; Thiophenes

2014
Risperidone and the 5-HT2A receptor antagonist M100907 improve probabilistic reversal learning in BTBR T + tf/J mice.
    Autism research : official journal of the International Society for Autism Research, 2014, Volume: 7, Issue:5

    Topics: Animals; Antipsychotic Agents; Autistic Disorder; Disease Models, Animal; Fluorobenzenes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Piperidines; Probability Learning; Receptor, Serotonin, 5-HT2A; Reversal Learning; Risperidone; Serotonin 5-HT2 Receptor Antagonists

2014
Nest building is impaired in the Ts65Dn mouse model of Down syndrome and rescued by blocking 5HT2a receptors.
    Neurobiology of learning and memory, 2014, Volume: 116

    Topics: Animals; Cognition Disorders; Disease Models, Animal; Down Syndrome; Gene Expression; Mice; Nesting Behavior; Phenotype; Receptor, Serotonin, 5-HT2A; Risperidone; Serotonin 5-HT2 Receptor Antagonists

2014
Activation of 5-HT2A/C receptor reduces glycine receptor-mediated currents in cultured auditory cortical neurons.
    Amino acids, 2016, Volume: 48, Issue:2

    Topics: Amphetamines; Animals; Auditory Cortex; Cells, Cultured; GTP-Binding Proteins; Guanosine Diphosphate; Ion Channels; Microtubules; Neurons; Nocodazole; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Glycine; Risperidone; Ritanserin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Strychnine; Thionucleotides; Tubulin Modulators

2016
Reformulating a Pharmacophore for 5-HT2A Serotonin Receptor Antagonists.
    ACS chemical neuroscience, 2016, 09-21, Volume: 7, Issue:9

    Topics: Animals; Barium; Calcium; G Protein-Coupled Inwardly-Rectifying Potassium Channels; HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Ketanserin; Membrane Potentials; Mutation; Oocytes; Protein Binding; Receptor, Serotonin, 5-HT2A; Risperidone; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Tritium; Xenopus laevis

2016
Preparation and in vivo evaluation of a gel-based nasal delivery system for risperidone.
    Acta pharmaceutica (Zagreb, Croatia), 2016, Dec-01, Volume: 66, Issue:4

    Topics: Administration, Intranasal; Animals; Antipsychotic Agents; Anura; Biological Availability; Cilia; Dopamine D2 Receptor Antagonists; Drug Compounding; Drug Delivery Systems; Gels; In Vitro Techniques; Male; Mouth Mucosa; Nasal Absorption; Nasal Mucosa; Palate; Random Allocation; Rats, Wistar; Risperidone; Serotonin 5-HT2 Receptor Antagonists

2016
Synthesis and biological evaluation of a series of novel pyridinecarboxamides as potential multi-receptor antipsychotic drugs.
    Bioorganic & medicinal chemistry letters, 2018, 02-15, Volume: 28, Issue:4

    Topics: Animals; Antipsychotic Agents; Aripiprazole; Dopamine D2 Receptor Antagonists; Humans; Male; Mice, Inbred ICR; Microsomes, Liver; Molecular Structure; Picolinic Acids; Risperidone; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Structure-Activity Relationship

2018
Serotonin 5-HT
    Neuropharmacology, 2019, 11-01, Volume: 158

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Brain Waves; Cortical Synchronization; Dopamine Agonists; Dopamine Antagonists; Electroencephalography; Fluorobenzenes; Gamma Rhythm; Haloperidol; Hippocampus; Locomotion; Mice; Neural Pathways; Piperazines; Piperidines; Prefrontal Cortex; Pyridines; Quinpirole; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists

2019
Risperidone and 5-HT2A Receptor Antagonists Attenuate and Reverse Cocaine-Induced Hyperthermia in Rats.
    The international journal of neuropsychopharmacology, 2020, 12-29, Volume: 23, Issue:12

    Topics: Animals; Benzazepines; Cocaine; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Haloperidol; Hyperthermia; Ketanserin; Male; Rats; Rats, Wistar; Risperidone; Ritanserin; Serotonin 5-HT2 Receptor Antagonists

2020
Serotonin 2A (5-HT
    Scientific reports, 2020, 12-10, Volume: 10, Issue:1

    Topics: Amphetamines; Animals; Antipsychotic Agents; Cell-Matrix Junctions; Chlorpromazine; HEK293 Cells; Humans; Mental Disorders; Olanzapine; Rats; Receptor, Serotonin, 5-HT2A; Risperidone; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Stress Fibers

2020