risperidone has been researched along with clozapine in 944 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 249 (26.38) | 18.2507 |
| 2000's | 449 (47.56) | 29.6817 |
| 2010's | 208 (22.03) | 24.3611 |
| 2020's | 38 (4.03) | 2.80 |
| Authors | Studies |
|---|---|
| Baldy, WJ; Barrett, DL; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Kukla, MJ; Martin, GE; Mathiasen, JR; Scott, MK | 1 |
| Arnt, J; Bøgesø, KP; Hyttel, J; Perregaard, J; Sánchez, C | 1 |
| Dunn, RW; Errico, CL; Hrib, NJ; Huger, FP; Jurcak, JG | 1 |
| Bordeau, KJ; Chiang, Y; Conway, PG; Corbett, R; Glamkowski, EJ; Hartman, HB; Helsley, GC; Strupczewski, JT; Szewczak, MR; Wilmot, CA | 1 |
| Baron, BM; de Paulis, T; Guan, HC; Neergaard, JR; Phillips, ST; Seeman, P; Siegel, BW; Smith, HE; Van Tol, HH | 1 |
| Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A | 1 |
| Burgher, KL; Conway, PG; Hartman, HB; Hrib, NJ; Jurcak, JG; Kerman, LL; Roehr, JE; Woods, AT | 1 |
| Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR | 1 |
| Ewing, FE; Furman, JS; Howard, HR; Jackson, E; Johnson, C; Lowe, JA; Maloney, PR; Morrone, J; Newman, ME; Robinson, GL; Schmidt, AW; Seeger, TF; Seymour, PA; Zorn, SH | 1 |
| Anglada, L; Bolós, J; Burgarolas, C; Castelló, JM; Gubert, S; Ortiz, JA; Planas, JM; Sacristán, A | 1 |
| Bregna, DE; Burgher, KL; Corbett, R; Hartman, HB; Hrib, NJ; Jurcak, JG; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT | 1 |
| De Loore, K; Gommeren, W; Janssen, PF; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van Gompel, P | 1 |
| Navas, F; Norman, MH; Rigdon, GC; Thompson, JB | 1 |
| Cai, J; Hartman, HB; Kerman, LL; Kongsamut, S; Roehr, JE; Sandrasagra, A; Tang, L; Weissensee, P | 1 |
| Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Reitz, AB; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL | 1 |
| Egan, CT; Herrick-Davis, K; Teitler, M | 1 |
| Brown, AM; Collin, LL; Ellis, CE; Forbes, IT; Gittins, SA; Gloger, I; Hagan, J; Middlemiss, DN; Riley, G; Thomas, DR | 1 |
| Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L | 1 |
| Agut, J; Anglada, L; Bolós, J; De la Fuente, N; Gubert, S; Ortiz, JA; Planas, JM; Príncep, M; Sacristán, A | 1 |
| Cadavid, MI; Carotti, A; Carrieri, A; Cid, J; Fontenla, JA; Loza, MI; Lozoya, E; Masaguer, CF; Negreira, J; Raviña, E; Rivas, ME; Rosa, E; Sanz, F; Tristán, H | 1 |
| Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Grinde, E; Herrick-Davis, K; Teitler, M | 1 |
| Cadavid, MI; Casariego, I; Demontis, GC; Enguix, MJ; Fontenla, JA; Loza, MI; Masaguer, CF; Montenegro, GY; Raviña, E; Rivas, ME; Villazon, M | 1 |
| Bristow, LJ; Hutson, PH; Rowley, M | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Itoh, H; Muramatsu, I; Taniguchi, T; Yoshio, R | 1 |
| de Moes, J; Feenstra, RW; Hofma, JJ; Kling, H; Kruse, CG; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA | 1 |
| Brea, J; Cadavid, MI; Caro, Y; Carotti, A; Carrieri, A; Centeno, NB; Enguix, MJ; Loza, MI; Masaguer, CF; Mengod, G; Raviña, E; Rodrigo, J; Sanz, F; Villazón, M | 1 |
| Boulton, DW; DeVane, CL; Liston, HL; Markowitz, JS | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M | 1 |
| Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S | 1 |
| Glennon, RA | 1 |
| Keserü, GM | 1 |
| Brea, J; Caro, Y; Loza, MI; Masaguer, CF; Padín, F; Raviña, E; Torrado, M | 1 |
| Wermuth, CG | 1 |
| Li, J; Rajamani, R; Reynolds, CH; Tounge, BA | 1 |
| Alonso, JM; Andrés, JI; Cid, JM; Díaz, A; Fernández, J; Gil, P; Iturrino, L; Megens, A; Sipido, VK; Trabanco, AA | 1 |
| Herrick-Davis, K; Purohit, A; Smith, C; Teitler, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Huang, AS; Kim, SF; Snowman, AM; Snyder, SH; Teuscher, C | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Areias, FM; Barceló, M; Brea, J; Domínguez, E; Loza, MI; Masaguer, CF; Raviña, E | 1 |
| Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Coolen, HK; Glennon, JC; Kruse, CG; Lange, JH; Reinders, JH; Tolboom, JT | 1 |
| Farasati, NA; Huang, Y; Randhawa, P | 1 |
| Shahid, M; Walker, GB; Wong, EH; Zorn, SH | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Ablordeppey, SY; Altundas, R; Bricker, B; Jackson, T; Khan, A; Kumar, EV; Roth, BL; Zhu, XY | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Andreasen, JT; Bernetti, M; Borriello, M; Brindisi, M; Butini, S; Cagnotto, A; Campiani, G; Ceres, N; Coccone, SS; De Angelis, M; Fattorusso, C; Fiorini, I; Franceschini, S; Gemma, S; Mennini, T; Mikkelsen, JD; Nacci, V; Novellino, E; Ros, S; Sandager-Nielsen, K; Scheel-Kruger, J; Trotta, F | 1 |
| Caron, G; Ermondi, G; Visentin, S | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Bali, A; Dhir, H; Kumar, A; Malhotra, S; Sharma, A | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Giordanetto, F; Leach, AG; Zachariae, U | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Brea, J; Carro, L; Domínguez, E; Loza, MI; Masaguer, CF; Raviña, E | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Jensen, AA; Kehler, J; Krogsgaard-Larsen, N | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ | 1 |
| Sen, S; Sinha, N | 1 |
| Bartolome, JM; Langlois, X; Macdonald, GJ; Tresadern, G | 1 |
| Cremers, TI; Flik, G; Hofland, C; Stratford, RE | 1 |
| Chappie, TA; Helal, CJ; Hou, X | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Chen, Y; Liu, BF; Liu, S; Liu, X; Qiu, Y; Wang, S; Xu, X; Yu, M; Zhang, G; Zhang, T; Zhao, S | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Brea, J; Carro, L; Lage, S; Loza, MI; Masaguer, CF; Raviña, E; Torrado, M | 1 |
| Chen, Y; Lan, Y; Liu, BF; Liu, X; Wang, S; Xu, X; Yu, M; Zhang, G; Zhang, H | 1 |
| Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A | 1 |
| Andreassi, M; Brindisi, M; Brogi, S; Butini, S; Cagnotto, A; Campiani, G; Casagni, A; Franceschini, S; Gemma, S; Gorelli, B; Mikkelsen, JD; Novellino, E; Ros, S; Salmona, M; Sandager-Nielsen, K; Saponara, S; Scheel-Kruger, J; Trotta, F; Weikop, P | 1 |
| Chen, B; Huang, L; Song, J; Yin, L; Zhang, W; Zhang, X | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cao, X; Chen, Y; Liu, BF; Liu, X; Qiu, Y; Xu, X; Yu, M; Zhang, G; Zhang, L; Zhang, Y | 1 |
| Freeman, BB; Rankovic, Z; Yang, L | 1 |
| Fu, W; Li, W; Li, X; Peng, W; Zhao, B; Zhu, C | 1 |
| Lippmann, S; Pary, R; Tobias, CR | 1 |
| Cooper, TB; Koreen, AR; Kronig, M; Lieberman, JA | 1 |
| Kerwin, R | 1 |
| Jeffries, JJ | 1 |
| MacEwan, GW | 1 |
| Kane, JM | 5 |
| Heinrich, K; Hruschka, H; Kinzler, E; Klieser, E; Lehmann, E | 1 |
| Janssen, PF; Leysen, JE; Megens, AA; Schotte, A | 1 |
| Czyrak, A; Frankiewicz, T; Maj, J; Rogóz, Z; Skuza, G | 1 |
| Aghajanian, GK; Gellman, RL | 1 |
| Kerwin, RW | 1 |
| Dalby, JT; Dickson, R; Williams, R | 1 |
| Mok, H; Yatham, LN | 1 |
| Janssen, PM; Leysen, JE; Megens, AA; Schotte, A | 1 |
| Goodman, WK; McDougle, CJ; Price, LH | 1 |
| Goldberg, TE; Weinberger, DR | 1 |
| Brocco, M; Millan, MJ; Schreiber, R | 1 |
| Janssen, PM; Leysen, JE; Luyten, WH; Megens, AA; Schotte, A | 1 |
| Beaudry, P; Bélanger, MC; Chouinard, G; Miller, R; Roy, JY; Turnier, L; Vainer, JL | 1 |
| Perrault, G; Sanger, DJ | 1 |
| Remington, GJ | 1 |
| Sigmundson, HK | 1 |
| Lee, MA; Meltzer, HY; Ranjan, R | 1 |
| Clarke, DE; Yaeger, SF | 1 |
| Bryois, C | 1 |
| Heinrich, K; Kinzler, E; Klieser, E; Lehmann, E; Wurthmann, C | 1 |
| DeVane, CL | 1 |
| Love, RC | 1 |
| Perry, PJ | 1 |
| Breier, A | 2 |
| Pickar, D | 1 |
| Zimbroff, DL | 1 |
| Lindenmayer, JP | 1 |
| Azorin, JM | 1 |
| Farde, L; Hall, H; Halldin, C; Nyberg, S; Sedvall, G | 1 |
| McCarthy, RH; Terkelsen, KG | 1 |
| Cott, J; Lieberman, JA; Matthews, S; Shore, D | 1 |
| Borison, RL; Brown, TM; Radford, JM | 1 |
| Jerkovich, GS; Lacey, RL; Preskorn, SH | 1 |
| Devane, CL; Risch, SC; Tyson, SC | 1 |
| Benvenga, MJ; Leander, JD | 1 |
| Kane, JM; McGlashan, TH | 1 |
| Healy, D; Johnstone, F; Rickard, I | 1 |
| Conway, PG; Corbett, R; Cornfeldt, M; Rush, DK; Strupczewski, JT; Szewczak, MR; Wilmot, CA | 1 |
| Beck, BJ | 1 |
| Pelonero, AL | 1 |
| Brecher, M; Klausner, M | 1 |
| Conway, PC; Corbett, R; Dunn, RW; Hartman, H; Helsley, GC; Kerman, LL; Strupczewski, JT; Woods, AT | 1 |
| Matsubara, R | 1 |
| Menkes, DB | 1 |
| Assié, MB; Koek, W; Sleight, AJ | 1 |
| Czyrak, A; Jaros, T; Maj, J; Moryl, E | 1 |
| Burgess, LH; Meltzer, HY; Roth, BL; Sibley, DR; Tandra, S | 1 |
| Friedman, JH; Ott, BR; Rich, SS | 1 |
| Deveaugh-Geiss, J; Doraiswamy, M; Martin, W; Metz, A | 1 |
| Avnon, M; Kunin, A | 1 |
| Kapur, S; Remington, G | 3 |
| Roman, B; Songer, DA | 1 |
| Daniel, DG; Goldberg, TE; Kleinman, JE; Lubick, LJ; Pickar, D; Weinberger, DR; Williams, TS | 1 |
| Godleski, LS; Sernyak, MJ | 1 |
| Keck, PE; McElroy, SL; Strakowski, SM | 3 |
| Eastham, JH; Field, MG; Gierz, M; Harris, MJ; Jeste, DV; Lacro, JP | 1 |
| Marder, SR | 4 |
| Daniel, DG; Gupta, S | 1 |
| Fukuda, T; Futamura, T; Haga, K; Ohashi, Y; Takahashi, Y; Yano, K | 1 |
| Byerly, MJ; DeVane, CL | 1 |
| Marr, I; Schlicker, E | 1 |
| DeLeon, J; Nair, C; Simpson, GM; Verghese, C | 1 |
| Farde, L; Halldin, C; Nakashima, Y; Nordström, AL; Nyberg, S | 1 |
| Meyer, JM; Simpson, GM | 1 |
| Bauer, U; Gallhofer, B; Gruppe, H; Krieger, S; Lis, S | 1 |
| Baumann, P; Bondolfi, G; Dufour, H | 1 |
| Chong, SA; Lee, HS; Tan, CH | 2 |
| Davis, JM; Janicak, PG | 1 |
| Carpenter, WT | 1 |
| Peterson, BS | 1 |
| Hargreaves, WA; Shumway, M | 1 |
| McCoy, L; Richfield, EK | 1 |
| Stip, E | 1 |
| Nabeshima, T; Noda, Y | 1 |
| Ishibashi, T; Ishida-Tokuda, K; Morita, T; Nakamura, M; Ohno, Y; Sakamoto, H; Tojima, R; Wakabayashi, J | 1 |
| Kapur, S | 2 |
| Hertel, P; Iurlo, M; Nomikos, GG; Svensson, TH | 1 |
| Skarsfeldt, T | 1 |
| Casey, DE | 3 |
| Aquila, R; Standard, J; Weiden, P | 1 |
| Lieberman, JA | 1 |
| Freeman, DJ; Li, MC; Oyewumi, K | 1 |
| Assion, HJ; Kolbinger, HM; Laux, G; Rao, ML | 1 |
| Bakshi, V; Geyer, MA; Swerdlow, NR | 1 |
| Morrison, DP | 1 |
| Keks, NA | 1 |
| Cox, C; McCoy, L; Richfield, EK | 2 |
| Griffon, N; Pilon, C; Sautel, F; Schwartz, JC; Sokoloff, P | 1 |
| Tariot, PN | 1 |
| Citrome, L | 2 |
| Dhossche, D; Petrides, G | 1 |
| Green, AI; Patel, JK; Salzman, C; Tsuang, MT | 1 |
| Tamminga, CA | 3 |
| Crismon, ML; Dorson, PG; Pousson, C; Still, DJ | 1 |
| Bruggeman, R; Timmerman, W; Westerink, BH | 1 |
| Baldessarini, RJ; Benzo, J; Gardner, DM; Tohen, M; Zarate, CA | 1 |
| Eikelmann, B; Konrad, C; Schormair, C; Telger, K | 1 |
| Alreja, M; Liu, W | 1 |
| Borsini, F; Cerutti, M; Fodritto, F; Monferini, E; Volonté, M | 1 |
| Thorpe, L | 1 |
| Aberman, J; Carriero, D; Finn, M; Lyons, M; Salamone, JD; Trevitt, JT | 1 |
| Franz, M; Gallhofer, B; Lis, S; Plüddemann, K | 1 |
| Breier, A; Hadd, K; Malhotra, AK; Pickar, D; Su, TP | 1 |
| Taylor, D | 1 |
| Kopala, LC | 1 |
| Finkel, SI | 1 |
| Fischer, TR; Hitchcock, JM; Lister, S; Wettstein, JG | 1 |
| Fogelson, DL; Payne, D; Sternbach, H | 1 |
| Schooler, NR | 1 |
| Hertel, P; Nomikos, GG; Svensson, TH | 1 |
| Freeman, MP; Stoll, AL | 1 |
| Collins, SP; Mendes, LS | 1 |
| Grossberg, GT; Zayas, EM | 1 |
| Daniel, DG; Whitcomb, SR | 1 |
| Tohen, M; Zarate, CA | 1 |
| Hillard, JR | 1 |
| O'Callaghan, E; Scully, PJ; Waddington, JL | 1 |
| Ballús, C | 1 |
| Fleischhacker, WW; Lieberman, JA; Miller, CH; Mohr, F; Umbricht, D; Woerner, M | 1 |
| Pollock, BG; Sweet, RA | 1 |
| Altman, S; Flynn, SW; Fredrikson, DH; Honer, WG; Kopala, LC; MacEwan, GW; Smith, GN | 1 |
| Altshuler, LL; Corá-Locatelli, G; Denicoff, K; Dunn, RT; Frye, MA; Ketter, TA; Kimbrell, TA; Post, RM | 1 |
| Baumann, P; Billeter, U; Bondolfi, G; Dufour, H; Eap, CB; May, JP; Patris, M | 1 |
| Zito, JM | 1 |
| Brar, JS; Ganguli, R | 1 |
| Abraham, G; Josiassen, RC; Monaco, CA; Pollock, BG; Tracy, JI | 1 |
| Asenbaum, S; Barnas, C; Brücke, T; Hesselmann, B; Kasper, S; Küfferle, B; Podreka, I; Tauscher, J | 1 |
| Hoes, MJ | 1 |
| Dähne, I; Dresel, S; Hahn, K; Mager, T; Scherer, J; Tatsch, K | 1 |
| Raja, M | 1 |
| Wirshing, WC | 1 |
| Buckley, P; Hasan, S | 1 |
| Lemon, MD | 1 |
| Lewis, R | 1 |
| Goff, DC; Henderson, DC | 1 |
| Sharif, ZA | 1 |
| Allen, D; Apergi, FS; Czobor, P; Iskander, A; Lindenmayer, JP; Park, M; Smith, R | 1 |
| Bloor, K; Maynard, A | 1 |
| Depoortere, R; Perrault, G; Sanger, DJ | 1 |
| Brewerton, TD; Jefferson, AM; Markowitz, JS | 1 |
| de Boer, P; de Vries, JB; Kruse, CG; Long, SK; Westerink, BH | 1 |
| Drici, MD; Flockhart, DA; Liu, XK; Wang, WX; Woosley, RL | 1 |
| Harris, MJ; Jeste, DV; Lacro, J; Lohr, JB; Rockwell, E | 1 |
| Laor, N; Toren, P; Weizman, A | 1 |
| Acton, PD; Busatto, GF; Costa, DC; Ell, PJ; Gacinovic, S; Kerwin, RW; Mertens, J; Mulligan, R; Pilowsky, LS; Terrière, D; Travis, MJ | 1 |
| Kapur, S; Remington, G; Zipursky, RB | 1 |
| Adler, CM; Breier, AF; Clifton, A; Elman, I; Lafargue, RT; Malhotra, AK; Pickar, D; Pinals, DA; Su, TP | 1 |
| Malone, RP; Sheikh, R; Zito, JM | 1 |
| Hawkins, KA; Mohamed, S; Woods, SW | 1 |
| Adler, CM; Breier, A; Elman, I; Malhotra, AK; Pickar, D; Su, TP; Weisenfeld, NI | 1 |
| Bahro, M; Kämpf, C; Strnad, J | 1 |
| Brown, RE; Genduso, LA; Hamilton, SH; Palmer, CS; Revicki, DA | 1 |
| Ginsberg, G; Lev, B; Shani, S | 1 |
| Cohen, LJ | 1 |
| Citrome, L; Volavka, J | 2 |
| Purdon, SE | 1 |
| Revicki, DA | 2 |
| Kuntz, AJ; Tollefson, GD | 1 |
| Barreiro, P; Cano-Muñoz, JL; Morera, AL | 1 |
| Bergqvist, PB; Blier, P; Dong, J | 1 |
| Jibson, MD; Milner, K; Tandon, R | 1 |
| Schneider, LS | 1 |
| Stahl, SM | 3 |
| Buckley, PF | 2 |
| Bartko, JJ; Conley, RR; Kelly, DL; Love, RC | 1 |
| Aquila, R; Emanuel, M | 1 |
| Alsayegh, L; Backstrom, JR; Berry, SA; Friedman, L; Roth, BL; Sanders-Bush, E; Willins, DL | 1 |
| Meltzer, HY | 1 |
| Rubin, E | 1 |
| Chatterjee, A; Dunayevich, E | 1 |
| Berisford, MA; Goldstein, D; Kysar, L; Marder, SR; Mintz, J; Pashdag, J; Wirshing, DA; Wirshing, WC | 1 |
| Baker, RW; Brar, JS; Chengappa, KN; Gopalani, A; Marcus, S; Palmer, A; Parepally, H; Schooler, NR; Sheth, S | 1 |
| Chang, WH; Lane, HY; Su, KP | 1 |
| Carboni, E; Di Chiara, G; Rolando, MT; Silvagni, A | 2 |
| McGurk, SR; Meltzer, HY | 1 |
| Baker, GB; Chue, PS; Prior, TI; Tibbo, P | 1 |
| Müssigbrodt, HE; Wetterling, T | 1 |
| Kalinyak, CM | 1 |
| Chang, WH; Lane, HY | 1 |
| Chaki, S; Funakoshi, T; Kumagai, T; Nagamine, M; Nakazato, A; Okuyama, S; Tomisawa, K; Yoshikawa, R | 1 |
| Braus, DF; Ende, G; Henn, FA; Hubrich-Ungureanu, P; Krier, A; Ruf, M; Sartorius, A; Stuck, S; Weber-Fahr, W | 1 |
| Amin, S | 1 |
| Yui, K | 1 |
| McCombs, JS; Nichol, MB; Shi, J; Smith, RR; Stimmel, GL | 1 |
| Masand, PS | 2 |
| Fukuda, K; Hondo, H; Kuroki, T; Nakahara, T; Tsutsumi, T; Uchimura, H; Yao, H | 1 |
| Bayle, FJ; Ghaoui, S; Olie, JP | 1 |
| Dufresne, RL; Ghaeli, P | 1 |
| Altson, K; Bootle, A; Culhane, C; Doherty, P; Hope, J; Keks, NA; Krapivensky, N; Tanaghow, A | 1 |
| Berent, S; Earnst, KS; Goldman, RS; Smet, IC; Tandon, R; Taylor, SF | 1 |
| Ahlenius, S; Oerther, S | 1 |
| Kulkarni, SK; Ninan, I | 1 |
| Hamer, RM; Simpson, PM | 1 |
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| Hammarlund-Udenaes, M; Jansson, B; König, F; Loryan, I; Melander, E; Payan, M; Svensson, M | 1 |
| Dold, M; Gianatsi, M; Helfer, B; Leucht, S; Nikolakopoulou, A; Salanti, G; Samara, MT | 1 |
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| Baymeeva, NV; Burminskiy, DS; Miroshnichenko, II; Morozova, MA; Platova, AI; Potanin, SS | 1 |
| Chen, J; Li, Y; Liang, S; Shi, S; Shi, Y; Wang, Y; Xu, Y; Yang, L | 1 |
| Ames, D; Baker, RW; Chengappa, KN; Kane, JM; Marder, SR; McMeniman, M; Parepally, H; Petrides, G; Schooler, NR; Umbricht, D; Wirshing, WC | 1 |
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| Chen, CC; Chen, CL; Goto, S; Hsu, LW; Huang, KT; Nakano, T | 1 |
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| Brüstle, O; Efstathopoulos, P; Kumar, P; Lavebratt, C; Millischer, V; Olsson, E; Ösby, U; Schalling, M; Villaescusa, JC; Wei, YB | 1 |
| Bech, P; Correll, CU; Foldager, L; Mors, O; Østergaard, SD | 1 |
| Dias Alves, M; Micoulaud-Franchi, JA; Simon, N; Vion-Dury, J | 1 |
| Davis, JM; Leucht, S; Smith, RC | 1 |
| Deckert, J; Hommers, LG; Menke, A; Samanski, L; Scherf-Clavel, M; Unterecker, S | 1 |
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| Lin, JR; Nakagawasai, O; Nemoto, W; Odaira, T; Onogi, H; Sakuma, W; Srivastava, LK; Takahashi, K; Tan-No, K | 1 |
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| Bijker, BJ; Bos, JHJ; Isphording, L; Luykx, JJ; Okhuijsen-Pfeifer, C; Schuiling-Veninga, CCM; Stam, N; Taipale, H; Tanskanen, A; Tiihonen, J | 1 |
| Grishina, NK; Khannanova, AN; Portnova, GV; Proskurnina, EV; Sokolova, SV; Sozarukova, MM | 1 |
| Claro, A; Corte-Real, F; Franco, J; Monteiro, C; Mustra, C; Proença, P | 1 |
| Gong, Q; Hu, N; Lencer, R; Li, S; Lui, S; Luo, C; Xiao, Y; Zhang, W | 1 |
| Dillon, BA; Dong, R; Du, XD; Jia, Q; Yang, Y; Yu, L; Yuan, L; Zhang, XY | 1 |
| Broadbent, M; Dobson, RJB; Dzahini, O; Govind, R; Ibrahim, ZM; Iqbal, E; Kim, CH; MacCabe, JH; Romero, A; Smith, T; Stewart, R; Werbeloff, N | 1 |
| Bernardo, M; García-Rizo, C; Gómez-Huelgas, R; Rico-Villademoros, F; Rojo, R | 1 |
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| Dziedzicka-Wasylewska, M; Jankowska, U; Kedracka-Krok, S; Prus, G; Skupien-Rabian, B; Swiderska, B | 1 |
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| Bakker, IM; Kamphuis, J; Schoevers, RA; Smith-Apeldoorn, SY; Touw, DJ; Veraart, JKE; Visser, BAE | 1 |
| Andrén, PE; Hammarlund-Udenaes, M; Loryan, I; Luptáková, D; Nilsson, A; Shariatgorji, R; Vallianatou, T | 1 |
| Cao, H; Gong, Q; Lencer, R; Lui, S; Tao, B; Xiao, Y; Yang, C; Zhang, W | 1 |
| Azimi Sanavi, M; Ghalehnoei, H; Ghazvini, H; Hosseini-Khah, Z; Zargari, M | 1 |
| Delgado-Sallent, C; Fath, AB; Gener, T; Nebot, P; Puig, MV; Timplalexi, M | 1 |
| Antoni, FA; Barkóczy, J; Chazot, P; Cunningham, MO; Etherington, LA; Gacsályi, I; Hársing, LG; Jay, TM; Lambert, JJ; Lévay, GI; Megyeri, K; Rocher, C; Schenker, E; Sebban, C; Spedding, M; Szénási, G; Tesolin-Decros, B; Thomson, I; Whittington, MA | 1 |
| Konradsson-Geuken, Å; Mazrina, J; Radhe, O; Ström, A; Svensson, TH; Titulaer, J | 1 |
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| Chiappini, S; Giannantonio, MD; Martinotti, G; Miuli, A; Mosca, A; Pettorruso, M; Santovito, MC; Sensi, SL; Skryabin, V | 1 |
| Bartels-Velthuis, AA; Bruggeman, R; Burin, LM; Cahn, W; da Rocha, NS; de Haan, L; Hahn, MK; Schirmbeck, F; Simons, CJP; van Amelsvoort, T; van Os, J | 1 |
| Arango, C; Leucht, S; Lopez-Morinigo, JD | 1 |
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| Gupta, B; Lee, J; Pilunthanakul, T; Ting, MQJ | 1 |
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| Cheung, H; Dima, A; Dzahini, O; Oloyede, E; Shergill, S; Taylor, D; Whiskey, E | 1 |
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236 review(s) available for risperidone and clozapine
| Article | Year |
|---|---|
Current and novel approaches to the drug treatment of schizophrenia.
Topics: Animals; Antipsychotic Agents; Cholinergic Agonists; Disease Models, Animal; Dopamine Antagonists; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Mice; Mice, Transgenic; Nitric Oxide Synthase; Receptor, Serotonin, 5-HT2A; Receptors, AMPA; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotensin; Receptors, Serotonin; Schizophrenia; Serotonin Antagonists | 2001 |
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
Selective optimization of side activities: another way for drug discovery.
Topics: Animals; Biological Availability; Combinatorial Chemistry Techniques; Databases, Factual; Drug Design; Humans; Patents as Topic; Pharmaceutical Preparations; Structure-Activity Relationship | 2004 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Practical approaches to evaluating and optimizing brain exposure in early drug discovery.
Topics: Animals; Blood-Brain Barrier; Central Nervous System; Central Nervous System Agents; Drug Delivery Systems; Drug Discovery; Humans; Molecular Structure; Structure-Activity Relationship | 2019 |
Chronic schizophrenia. Options for pharmacologic management.
Topics: Antipsychotic Agents; Chronic Disease; Clozapine; Drug Therapy, Combination; Humans; Lithium; Psychotropic Drugs; Risperidone; Schizophrenia | 1995 |
Ethical issues in drug selection for schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Dyskinesia, Drug-Induced; Ethics, Medical; Humans; Informed Consent; Isoxazoles; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology | 1993 |
New antipsychotic medications: do research results relate to clinical practice?
Topics: Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Dyskinesia, Drug-Induced; Humans; Isoxazoles; Neurologic Examination; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1993 |
Newer antipsychotic drugs. A review of their pharmacology and therapeutic potential.
Topics: Antipsychotic Agents; Clozapine; Humans; Isoxazoles; Piperidines; Remoxipride; Risperidone; Schizophrenia; Treatment Outcome | 1993 |
The new atypical antipsychotics. A lack of extrapyramidal side-effects and new routes in schizophrenia research.
Topics: Antipsychotic Agents; Brain; Clozapine; Dyskinesia, Drug-Induced; Extrapyramidal Tracts; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Receptors, Dopamine; Receptors, Serotonin; Remoxipride; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Dopamine antagonists in tic-related and psychotic spectrum obsessive compulsive disorder.
Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Clomipramine; Clozapine; Dopamine Antagonists; Drug Therapy, Combination; Female; Fluvoxamine; Haloperidol; Humans; Isoxazoles; Male; Obsessive-Compulsive Disorder; Piperidines; Risperidone; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Tic Disorders; Tourette Syndrome | 1994 |
The effects of clozapine on neurocognition: an overview.
Topics: Clozapine; Cognition; Cognition Disorders; Dopamine; Humans; Isoxazoles; Neuropsychological Tests; Piperidines; Receptors, Dopamine; Receptors, Muscarinic; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1994 |
Pharmacotherapy of schizophrenia: a review.
Topics: Antipsychotic Agents; Brain; Clozapine; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Recent advances in the pharmacotherapy of schizophrenia.
Topics: Adult; Antipsychotic Agents; Brain; Clozapine; Dopamine; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1994 |
[New psychopharmacologic alternatives in treatment of schizophrenia].
Topics: Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Isoxazoles; Piperidines; Psychotropic Drugs; Remoxipride; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Brief comparison of the pharmacokinetics and pharmacodynamics of the traditional and newer antipsychotic drugs.
Topics: Antipsychotic Agents; Chlorpromazine; Clozapine; Haloperidol; Humans; Isoxazoles; Piperidines; Risperidone; Time Factors | 1995 |
Clinical use of the newer antipsychotic drugs.
Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Female; Formularies as Topic; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Risperidone; Schizophrenia | 1995 |
Serotonin, schizophrenia and antipsychotic drug action.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Humans; Isoxazoles; Piperazines; Piperidines; Risperidone; Schizophrenia; Serotonin; Tryptophan | 1995 |
Prospects for pharmacotherapy of schizophrenia.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Humans; Isoxazoles; Piperidines; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Schizophrenia | 1995 |
New pharmacotherapeutic modalities for negative symptoms in psychosis.
Topics: Affective Symptoms; Antipsychotic Agents; Clozapine; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Psychometrics; Risperidone; Schizophrenia; Schizophrenic Psychology; Syndrome | 1995 |
Long-term treatment of mood disorders in schizophrenia.
Topics: Affective Symptoms; Antidepressive Agents; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Isoxazoles; Lithium; Long-Term Care; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1995 |
Antipsychotic medication in the treatment of schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1995 |
Treatment of schizophrenia.
Topics: Antipsychotic Agents; Behavior Therapy; Clozapine; Cognitive Behavioral Therapy; Family Therapy; Humans; Isoxazoles; Piperidines; Psychotherapy; Rehabilitation, Vocational; Risperidone; Schizophrenia | 1995 |
Neuropsychiatric manifestations of diffuse Lewy body disease.
Topics: Alzheimer Disease; Antipsychotic Agents; Brain Stem; Clozapine; Dopamine Antagonists; Humans; Lewy Bodies; Neuropsychological Tests; Parkinson Disease; Risperidone | 1995 |
Psychosis in Parkinson's disease: diagnosis and treatment.
Topics: Clozapine; Diagnosis, Differential; Humans; Parkinson Disease; Psychotic Disorders; Risperidone | 1995 |
Serotonin-dopamine interaction and its relevance to schizophrenia.
Topics: Animals; Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Disease Models, Animal; Dopamine; Dopamine Agents; Drug Interactions; Humans; Mesencephalon; Neural Pathways; Prefrontal Cortex; Prosencephalon; Risperidone; Schizophrenia; Serotonin; Serotonin Agents | 1996 |
Mania, psychosis, and antipsychotics.
Topics: Adolescent; Adult; Age of Onset; Antipsychotic Agents; Bipolar Disorder; Clozapine; Humans; Prognosis; Psychiatric Status Rating Scales; Risk Factors; Risperidone; Severity of Illness Index | 1996 |
Management of late-life psychosis.
Topics: Adult; Age Factors; Age of Onset; Aged; Clozapine; Drug Administration Schedule; Humans; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Schizophrenia | 1996 |
Management of schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Combined Modality Therapy; Diagnosis, Differential; Humans; Psychiatric Status Rating Scales; Psychotherapy; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1996 |
Pharmacokinetics of clozapine and risperidone: a review of recent literature.
Topics: Antipsychotic Agents; Biological Availability; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Metabolic Clearance Rate; Risperidone; Schizophrenia; Schizophrenic Psychology | 1996 |
Antipsychotic dosing strategies in acute schizophrenia.
Topics: Acute Disease; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Delivery Systems; Haloperidol; Humans; Risperidone; Schizophrenia | 1996 |
Maintenance therapy of persons with schizophrenia.
Topics: Ambulatory Care; Antipsychotic Agents; Case Management; Clozapine; Combined Modality Therapy; Community Mental Health Services; Drug Administration Schedule; Drug Therapy, Combination; Humans; Recurrence; Risperidone; Schizophrenia; Schizophrenic Psychology | 1996 |
Considerations of natural history and pathophysiology in the psychopharmacology of Tourette's syndrome.
Topics: Adolescent; Adult; Age of Onset; Antipsychotic Agents; Child; Clozapine; Disease Progression; Diseases in Twins; Dopamine; Haloperidol; Humans; Obsessive-Compulsive Disorder; Phenotype; Pimozide; Risperidone; Tourette Syndrome; Treatment Outcome | 1996 |
Treatment-resistant schizophrenic patients.
Topics: Antipsychotic Agents; Clozapine; Double-Blind Method; Humans; Prospective Studies; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Treatment Outcome | 1996 |
New developments in the pharmacologic treatment of schizoaffective disorder.
Topics: Antidepressive Agents; Antipsychotic Agents; Carbamazepine; Clinical Trials as Topic; Clozapine; Drug Therapy, Combination; Humans; Psychotic Disorders; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Treatment Outcome; Valproic Acid | 1996 |
Pharmacoeconomics of antipsychotic drug therapy.
Topics: Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Cost-Benefit Analysis; Drug Costs; Economics, Pharmaceutical; Humans; Patient Selection; Psychotic Disorders; Research Design; Retrospective Studies; Risperidone; Schizophrenia | 1996 |
Memory impairment in schizophrenia: perspectives from psychopathology and pharmacotherapy.
Topics: Amnesia; Antipsychotic Agents; Cholinergic Antagonists; Clozapine; Dibenzothiazepines; Humans; Mental Recall; Neuropsychological Tests; Quetiapine Fumarate; Retention, Psychology; Risperidone; Schizophrenia; Schizophrenic Psychology | 1996 |
5-HT2 antagonism and EPS benefits: is there a causal connection?
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Humans; Receptors, Dopamine D2; Risperidone; Serotonin Antagonists | 1996 |
Management of treatment-resistant patients with schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Lithium; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Treatment Outcome | 1996 |
Side effect profiles of new antipsychotic agents.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clozapine; Dyskinesia, Drug-Induced; Humans; Imidazoles; Indoles; Neuroleptic Malignant Syndrome; Olanzapine; Pirenzepine; Psychotic Disorders; Risperidone; Schizophrenia; Seizures; Sleep; Weight Gain | 1996 |
Atypical antipsychotic drugs and long-term outcome in schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Clozapine; Follow-Up Studies; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Quality of Life; Recurrence; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1996 |
Atypical antipsychotic drugs as a first-line treatment of schizophrenia: a rationale and hypothesis.
Topics: Adolescent; Adult; Antipsychotic Agents; Child; Clozapine; Humans; Middle Aged; Patient Compliance; Recurrence; Risperidone; Schizophrenia; Treatment Outcome | 1996 |
Management of treatment refractory schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Combined Modality Therapy; Dose-Response Relationship, Drug; Drug Resistance; Family Therapy; Humans; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1996 |
Schizophrenia, violence, clozapine and risperidone: a review. The Special Hospitals Treatment Resistant Schizophrenia Research Group.
Topics: Antipsychotic Agents; Clozapine; Dangerous Behavior; Humans; Patient Admission; Patient Compliance; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; Violence | 1996 |
Minimizing the non-extrapyramidal side-effects of antipsychotics.
Topics: Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Dyskinesia, Drug-Induced; Humans; Neurologic Examination; Patient Education as Topic; Risperidone; Schizophrenia | 1996 |
Treatment strategies for agitation and psychosis in dementia.
Topics: Aged; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Clozapine; Dementia; Humans; Psychomotor Agitation; Psychotic Disorders; Risperidone; Selective Serotonin Reuptake Inhibitors; Trazodone | 1996 |
New antipsychotic medications: what advantages do they offer?
Topics: Antipsychotic Agents; Clozapine; Drug Costs; Humans; Psychotic Disorders; Risperidone; Schizophrenia; United States | 1997 |
The promise of new drugs for schizophrenia treatment.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1997 |
The treatment of psychotic disorders in late life.
Topics: Aged; Antipsychotic Agents; Clozapine; Humans; Neurocognitive Disorders; Neurologic Examination; Risperidone; Treatment Outcome | 1997 |
Pharmacokinetic interactions involving clozapine.
Topics: Anti-Bacterial Agents; Anticonvulsants; Antipsychotic Agents; Caffeine; Cimetidine; Clozapine; Drug Interactions; Erythromycin; Fluvoxamine; Humans; Risperidone; Selective Serotonin Reuptake Inhibitors | 1997 |
Clinical experience in developing treatment regimens with the novel antipsychotic risperidone.
Topics: Adolescent; Adult; Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Dopamine Antagonists; Drug Administration Schedule; Guidelines as Topic; Humans; Male; Patient Compliance; Risperidone; Schizophrenia; Serotonin Antagonists | 1997 |
Managing the behavioral and psychological signs and symptoms of dementia.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dementia; Humans; Olanzapine; Pirenzepine; Risperidone | 1997 |
New antipsychotic medications: strategies for evaluation and selected findings.
Topics: Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clinical Trials as Topic; Clozapine; Drug Administration Schedule; Drug Approval; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Placebos; Psychotic Disorders; Recurrence; Research Design; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; United States; United States Food and Drug Administration | 1997 |
Mood stabilizer combinations: a review of safety and efficacy.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Calcium Channel Blockers; Clinical Trials as Topic; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Risperidone; Valproic Acid | 1998 |
The treatment of psychosis in late life.
Topics: Age Factors; Aged; Antipsychotic Agents; Clozapine; Decision Trees; Delirium; Diagnosis, Differential; Drug Administration Schedule; Female; Half-Life; Humans; Male; Middle Aged; Nursing Homes; Psychotic Disorders; Risk Factors; Risperidone; United States | 1998 |
Treatment of the refractory schizophrenic patient.
Topics: Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Clozapine; Diagnosis, Differential; Humans; Imidazoles; Indoles; Olanzapine; Patient Compliance; Pirenzepine; Psychiatric Status Rating Scales; Receptors, Dopamine D2; Risperidone; Schizophrenia; Schizophrenic Psychology; Terminology as Topic; Treatment Failure | 1998 |
Antipsychotic agents and bipolar disorder.
Topics: Acute Disease; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Clozapine; Delayed-Action Preparations; Drug Therapy, Combination; Humans; Lithium; Olanzapine; Pirenzepine; Psychotic Disorders; Risperidone; Treatment Outcome | 1998 |
Emergency treatment of acute psychosis.
Topics: Acute Disease; Antipsychotic Agents; Benzodiazepines; Clozapine; Decision Trees; Drug Administration Schedule; Emergency Services, Psychiatric; Emergency Treatment; Haloperidol; History, 20th Century; Humans; Lorazepam; Olanzapine; Pirenzepine; Psychotic Disorders; Risperidone | 1998 |
Effects of antipsychotics on the clinical and psychosocial behavior of patients with schizophrenia.
Topics: Antipsychotic Agents; Behavioral Symptoms; Benzodiazepines; Clozapine; Family Health; Humans; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Social Adjustment | 1997 |
New atypical antipsychotics. Experience and utility in the elderly.
Topics: Aged; Aging; Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Randomized Controlled Trials as Topic; Risperidone; Treatment Outcome | 1998 |
Facilitating compliance with antipsychotic medication.
Topics: Antipsychotic Agents; Clozapine; Cognition; Drug Monitoring; Haloperidol; Health Care Costs; Humans; Patient Compliance; Quality of Life; Risk Factors; Risperidone; Schizophrenia; Treatment Refusal | 1998 |
Clozapine in bipolar disorder: treatment implications for other atypical antipsychotics.
Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Risperidone; Trimipramine | 1998 |
Pharmacoeconomics of the new antipsychotics for the treatment of schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Clozapine; Cost-Benefit Analysis; Humans; Olanzapine; Pirenzepine; Risperidone; Schizophrenia | 1998 |
A new framework for investigating antipsychotic action in humans: lessons from PET imaging.
Topics: Antipsychotic Agents; Binding, Competitive; Clozapine; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Humans; Models, Psychological; Protein Binding; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Schizophrenia; Serotonin; Serotonin Antagonists; Tomography, Emission-Computed | 1998 |
Recent developments in the management of psychosis.
Topics: Antipsychotic Agents; Clozapine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Humans; Psychotic Disorders; Risperidone; Serotonin Antagonists; Sulpiride | 1998 |
Novel antipsychotics and the neuroleptic malignant syndrome: a review and critique.
Topics: Adolescent; Adult; Antipsychotic Agents; Bipolar Disorder; Clozapine; Confidence Intervals; Female; Humans; Male; Middle Aged; Neuroleptic Malignant Syndrome; Probability; Psychotic Disorders; Risperidone; Schizophrenia | 1998 |
Typical and atypical antipsychotics in adolescent schizophrenia: efficacy, tolerability, and differential sensitivity to extrapyramidal symptoms.
Topics: Adolescent; Adolescent Psychiatry; Age Factors; Antipsychotic Agents; Benzodiazepines; Cholinergic Fibers; Clozapine; Controlled Clinical Trials as Topic; Corpus Striatum; Disease Susceptibility; Dyskinesia, Drug-Induced; Humans; Olanzapine; Pirenzepine; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed | 1998 |
Measuring outcome in schizophrenia: differences among the atypical antipsychotics. Collaborative Working Group on Clinical Trial Evaluations.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition Disorders; Cost-Benefit Analysis; Dibenzothiazepines; Drug Approval; Health Care Costs; Health Status; Hospitalization; Humans; Meta-Analysis as Topic; Olanzapine; Outcome Assessment, Health Care; Pirenzepine; Quality of Life; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; United States; United States Food and Drug Administration | 1998 |
Adverse effects of the atypical antipsychotics. Collaborative Working Group on Clinical Trial Evaluations.
Topics: Agranulocytosis; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Central Nervous System Diseases; Clozapine; Dibenzothiazepines; Drug Interactions; Dyskinesia, Drug-Induced; Health Status; Humans; Hypotension, Orthostatic; Olanzapine; Pirenzepine; Quality of Life; Quetiapine Fumarate; Receptors, Cholinergic; Risperidone; Schizophrenia; Sexual Dysfunctions, Psychological; Sleep Wake Disorders; Treatment Refusal; Weight Gain | 1998 |
Assessment of EPS and tardive dyskinesia in clinical trials. Collaborative Working Group on Clinical Trial Evaluations.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Drug Administration Schedule; Dyskinesia, Drug-Induced; Dystonia; Humans; Olanzapine; Parkinson Disease, Secondary; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Schizophrenia; Substance Withdrawal Syndrome | 1998 |
Assessing the effects of atypical antipsychotics on negative symptoms. Collaborative Working Group on Clinical Trial Evaluations.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Delusions; Depressive Disorder; Hallucinations; Humans; Models, Statistical; Multivariate Analysis; Psychiatric Status Rating Scales; Regression Analysis; Risperidone; Schizophrenia; Schizophrenic Psychology | 1998 |
Evaluating the effects of antipsychotics on cognition in schizophrenia. Collaborative Working Group on Clinical Trial Evaluations.
Topics: Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Cognition Disorders; Dibenzothiazepines; Humans; Neuropsychological Tests; Quality of Life; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1998 |
Atypical antipsychotics for treatment of depression in schizophrenia and affective disorders. Collaborative Working Group on Clinical Trial Evaluations.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Clozapine; Comorbidity; Depressive Disorder; Humans; Mood Disorders; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Suicide; Suicide Prevention | 1998 |
Treatment of special populations with the atypical antipsychotics. Collaborative Working Group on Clinical Trial Evaluations.
Topics: Adult; Age Factors; Aged; Algorithms; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Clozapine; Decision Trees; Dementia; Dibenzothiazepines; Female; Humans; Male; Mood Disorders; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone; Schizophrenia | 1998 |
Treatment refractory schizophrenia: how should we proceed?
Topics: Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Clozapine; Humans; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1998 |
Building castles on sands or quicksands? The strengths and weaknesses of economic evaluation in pharmaceuticals.
Topics: Clozapine; Decision Making; Drug Costs; Health Care Costs; Health Policy; Humans; Practice Guidelines as Topic; Program Evaluation; Risperidone; Schizophrenia | 1998 |
Conventional vs. newer antipsychotics in elderly patients.
Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Clozapine; Dementia; Dibenzothiazepines; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Schizophrenia | 1999 |
Use of atypical neuroleptics in child and adolescent psychiatry.
Topics: Adolescent; Adult; Age Factors; Antipsychotic Agents; Benzodiazepines; Child; Child Development Disorders, Pervasive; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Humans; Mental Disorders; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Remoxipride; Risperidone; Schizophrenia; Treatment Outcome | 1998 |
Will the novel antipsychotics significantly ameliorate neuropsychological deficits and improve adaptive functioning in schizophrenia?
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Cognition Disorders; Humans; Reaction Time; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index | 1999 |
Atypical antipsychotics in the treatment of the persistently aggressive psychotic patient: methodological concerns.
Topics: Aggression; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Disease Progression; Humans; Olanzapine; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Research Design; Risperidone | 1999 |
Cognitive improvement in schizophrenia with novel antipsychotic medications.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition Disorders; Dibenzothiazepines; Humans; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone; Schizophrenia; Severity of Illness Index | 1999 |
Tardive dyskinesia and atypical antipsychotic drugs.
Topics: Adult; Age Factors; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clozapine; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Sex Factors | 1999 |
Antipsychotic drugs and relapse prevention.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Secondary Prevention | 1999 |
Pharmacoeconomic studies of atypical antipsychotic drugs for the treatment of schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cost-Benefit Analysis; Humans; Olanzapine; Pirenzepine; Research Design; Risperidone; Schizophrenia | 1999 |
Cognitive deficit in schizophrenia and its neurochemical basis.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition Disorders; Glutamic Acid; Haloperidol; Humans; N-Methylaspartate; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Schizophrenic Psychology | 1999 |
Review of recent clinical studies with olanzapine.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Depressive Disorder; Drug Resistance; Humans; Olanzapine; Pirenzepine; Prolactin; Psychotic Disorders; Quality of Life; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia | 1999 |
Antipsychotics from theory to practice: integrating clinical and basic data.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dose-Response Relationship, Drug; Humans; Limbic System; Models, Biological; Olanzapine; Pirenzepine; Psychotic Disorders; Receptors, Neurotransmitter; Risperidone; Schizophrenia | 1999 |
Pharmacologic management of psychosis in dementia.
Topics: Aged; Antipsychotic Agents; Clozapine; Comorbidity; Delusions; Dementia; Hallucinations; Humans; Psychotic Disorders; Risperidone; Treatment Outcome | 1999 |
Selecting an atypical antipsychotic by combining clinical experience with guidelines from clinical trials.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Drug Administration Schedule; Humans; Olanzapine; Pirenzepine; Practice Guidelines as Topic; Quetiapine Fumarate; Risperidone; Schizophrenia; Terminology as Topic | 1999 |
The role of typical and atypical antipsychotic medications in the management of agitation and aggression.
Topics: Aggression; Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Loxapine; Mental Disorders; Olanzapine; Pirenzepine; Psychomotor Agitation; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology | 1999 |
The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia.
Topics: Antipsychotic Agents; Attention; Benzodiazepines; Clinical Trials as Topic; Clozapine; Cognition Disorders; Humans; Mental Recall; Neuropsychological Tests; Olanzapine; Pirenzepine; Risperidone; Verbal Learning | 1999 |
Drug metabolism and atypical antipsychotics.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cytochrome P-450 Enzyme System; Dibenzothiazepines; Drug Interactions; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone; Schizophrenia | 1999 |
Schizophrenia treatment: the use of atypical drugs--risperdal, zyperexa, and clozaril.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Nurse Clinicians; Olanzapine; Pirenzepine; Psychiatric Nursing; Risperidone; Schizophrenia | 1998 |
Cost-effectiveness of atypical antipsychotics in chronic schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Cost-Benefit Analysis; Humans; Risperidone; Schizophrenia; Treatment Failure | 1999 |
[Clinical efficacy of olanzapine].
Topics: Antipsychotic Agents; Benzodiazepines; Binding Sites; Clinical Trials as Topic; Clozapine; Dopamine D2 Receptor Antagonists; Haloperidol; Humans; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Schizophrenic Psychology; Secondary Prevention; Serotonin | 1999 |
Pharmacologic treatment of schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Pirenzepine; Quality of Life; Quetiapine Fumarate; Recurrence; Risperidone; Schizophrenia | 1999 |
[New antipsychotic agents].
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Sulpiride; Thiazoles | 1999 |
New antipsychotic medications: more than old wine and new bottles.
Topics: Agranulocytosis; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Humans; Olanzapine; Pirenzepine; Prolactin; Quetiapine Fumarate; Risperidone; Schizophrenia | 2000 |
The efficacy of atypical antipsychotics in the treatment of depressive symptoms, hostility, and suicidality in patients with schizophrenia.
Topics: Aggression; Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Clozapine; Depression; Depressive Disorder; Dibenzothiazepines; Hostility; Humans; Multicenter Studies as Topic; Olanzapine; Piperazines; Pirenzepine; Psychiatric Status Rating Scales; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Suicide; Thiazoles; Treatment Outcome | 2000 |
Extrapyramidal side effects, tardive dyskinesia, and the concept of atypicality.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Brain; Clozapine; Dibenzothiazepines; Humans; Movement Disorders; Olanzapine; Pirenzepine; Quetiapine Fumarate; Receptors, Dopamine; Receptors, Serotonin; Risk Factors; Risperidone | 2000 |
Expected incidence of tardive dyskinesia associated with atypical antipsychotics.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Double-Blind Method; Drug Administration Schedule; Dyskinesia, Drug-Induced; Haloperidol; Humans; Incidence; Molindone; Olanzapine; Pirenzepine; Prospective Studies; Risk Factors; Risperidone; Schizophrenia; Substance Withdrawal Syndrome; Survival Analysis | 2000 |
The treatment of tardive dyskinesia and tardive dystonia.
Topics: Adult; Akathisia, Drug-Induced; Algorithms; Antipsychotic Agents; Benzodiazepines; Clozapine; Decision Trees; Drug Administration Schedule; Dyskinesia, Drug-Induced; Dystonia; Female; Humans; Male; Olanzapine; Pirenzepine; Probability; Reserpine; Risperidone; Schizophrenia; Substance Withdrawal Syndrome; Tetrabenazine; Treatment Outcome; Vitamin E | 2000 |
[Atypical neuroleptics in child- and adolescent psychiatry].
Topics: Adolescent Psychiatry; Antipsychotic Agents; Benzodiazepines; Child; Child Psychiatry; Clozapine; Germany; Humans; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists | 2000 |
Antipsychotic drug side effect issues in bipolar manic patients.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone | 2000 |
[New i.e. atypical neuroleptic agents for negative symptoms of schizophrenia: results and methodological problems of evaluation].
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Double-Blind Method; Dyskinesia, Drug-Induced; Humans; Imidazoles; Indoles; Neurotransmitter Agents; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Schizophrenic Psychology; Sulpiride; Thiazoles | 2000 |
Atypical antipsychotics and weight gain--a systematic review.
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Risperidone; Sulpiride; Thiazoles; Weight Gain | 2000 |
Risperidone versus other atypical antipsychotic medication for schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Olanzapine; Pirenzepine; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia | 2000 |
[Atypical antipsychotic drugs].
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Netherlands; Olanzapine; Pirenzepine; Psychopharmacology; Quetiapine Fumarate; Risperidone; Schizophrenia; Serotonin Agents | 2000 |
Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis.
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Drug Costs; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Quetiapine Fumarate; Regression Analysis; Risperidone; Schizophrenia; Sulpiride | 2000 |
Atypical neuroleptics in child and adolescent psychiatry.
Topics: Adolescent; Adolescent Psychiatry; Antipsychotic Agents; Benzodiazepines; Binding Sites; Brain; Clozapine; Female; Humans; Male; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Tomography, Emission-Computed | 2000 |
An ever-increasing pharmacopoeia for the management of patients with bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electroconvulsive Therapy; Electromagnetic Phenomena; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Olanzapine; Pirenzepine; Risperidone; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2000 |
Rationale and guidelines for the inpatient treatment of acute psychosis.
Topics: Acute Disease; Antipsychotic Agents; Benzodiazepines; Clozapine; Drug Administration Schedule; Drug Therapy, Combination; Haloperidol; Hospitalization; Hostility; Humans; Olanzapine; Pirenzepine; Practice Guidelines as Topic; Psychomotor Agitation; Psychotic Disorders; Risperidone; Treatment Outcome | 2000 |
New treatments for bipolar disorder: the role of atypical neuroleptic agents.
Topics: Acute Disease; Algorithms; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Dibenzothiazepines; Drug Therapy, Combination; Humans; Lithium; Olanzapine; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Treatment Outcome; Valproic Acid | 2000 |
Atypical antipsychotics: new directions and new challenges in the treatment of schizophrenia.
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Dopamine Antagonists; Drug Monitoring; Haloperidol; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Receptors, Dopamine D2; Receptors, Dopamine D4; Risperidone; Schizophrenia; Schizophrenic Psychology; Serotonin Antagonists; Sulpiride; Thiazoles; Treatment Outcome | 2001 |
[Atypical neuroleptics: new approaches to drug therapy of schizophrenic disorders].
Topics: Aged; Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Controlled Clinical Trials as Topic; Dibenzothiazepines; Dibenzothiepins; Haloperidol; Humans; Imidazoles; Indoles; Multicenter Studies as Topic; Olanzapine; Piperazines; Pirenzepine; Placebos; Quetiapine Fumarate; Risperidone; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sulpiride; Thiazoles | 2000 |
Does fast dissociation from the dopamine d(2) receptor explain the action of atypical antipsychotics?: A new hypothesis.
Topics: Antipsychotic Agents; Benzodiazepines; Brain; Clozapine; Dopamine D2 Receptor Antagonists; Haloperidol; Humans; Olanzapine; Pirenzepine; Psychotic Disorders; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Serotonin; Risperidone; Schizophrenia; Terminology as Topic; Tomography, Emission-Computed | 2001 |
Priapism associated with conventional and atypical antipsychotic medications: a review.
Topics: Antipsychotic Agents; Benzodiazepines; Circadian Rhythm; Clozapine; Erectile Dysfunction; Female; Forensic Psychiatry; Humans; Male; Olanzapine; Pirenzepine; Priapism; Psychotic Disorders; Risperidone | 2001 |
Cost effectiveness of the newer atypical antipsychotics: a review of the pharmacoeconomic research evidence.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cost-Benefit Analysis; Dibenzothiazepines; Health Care Costs; Humans; Imidazoles; Indoles; Olanzapine; Pirenzepine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone | 2001 |
Atypical antipsychotics: impaired glucose metabolism.
Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Female; Glucose; Humans; Male; Metabolic Diseases; Middle Aged; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone | 2001 |
Dopamine D(2) receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient.
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Models, Neurological; Olanzapine; Pirenzepine; Quetiapine Fumarate; Receptors, Dopamine D2; Risperidone; Schizophrenia; Sulpiride | 2001 |
Broad therapeutic uses of atypical antipsychotic medications.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Child; Child Development Disorders, Pervasive; Clozapine; Dementia; Dibenzothiazepines; Humans; Mood Disorders; Olanzapine; Personality Disorders; Pirenzepine; Quetiapine Fumarate; Risperidone | 2001 |
Use of atypical antipsychotics in mood disorders.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Clozapine; Depressive Disorder, Major; Dibenzothiazepines; Humans; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Risperidone; Thiazoles | 2001 |
[Clinical and pharmacological studies of the second generation antipsychotics].
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition Disorders; Cytoskeletal Proteins; Dibenzothiazepines; Dopamine; Dopamine Antagonists; Humans; Nerve Tissue Proteins; Olanzapine; Pirenzepine; Proto-Oncogene Proteins c-fos; Quetiapine Fumarate; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Schizophrenia; Serotonin Antagonists | 2001 |
[Atypical neuroleptics in the treatment of aggression and hostility in schizophrenic patients].
Topics: Aggression; Antipsychotic Agents; Benzodiazepines; Clozapine; Hostility; Humans; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Schizophrenic Psychology | 2002 |
Movement disorders associated with atypical antipsychotic drugs.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Clozapine; Dyskinesia, Drug-Induced; Humans; Neuroleptic Malignant Syndrome; Neurotoxicity Syndromes; Olanzapine; Pirenzepine; Risperidone | 2002 |
Advances in atypical antipsychotics for the treatment of schizophrenia: new formulations and new agents.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dosage Forms; Humans; Isoxazoles; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quinolones; Risperidone; Schizophrenia; Thiazoles | 2002 |
Tardive dyskinesias and antipsychotics: a review.
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dyskinesia, Drug-Induced; Humans; Olanzapine; Pirenzepine; Prevalence; Psychotic Disorders; Risperidone; Sulpiride | 2002 |
Atypical antipsychotics in Parkinson-sensitive populations.
Topics: Alzheimer Disease; Antipsychotic Agents; Benzodiazepines; Clozapine; Dementia, Vascular; Dibenzothiazepines; Hallucinations; Humans; Iatrogenic Disease; Lewy Body Disease; Olanzapine; Parkinson Disease; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Risperidone | 2002 |
Atypical antipsychotics: experience and use in the elderly.
Topics: Aged; Aged, 80 and over; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition; Dementia; Dibenzothiazepines; Female; Humans; Male; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone; United Kingdom | 2002 |
[Treatment of tics in Tourette syndrome with atypical antipsychotic drugs].
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dopamine Antagonists; Humans; Olanzapine; Pirenzepine; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sulpiride; Tics; Tourette Syndrome | 2002 |
Antipsychotic combination therapy in schizophrenia. A review of efficacy and risks of current combinations.
Topics: Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Delirium; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Risk; Risperidone; Schizophrenia; Schizophrenic Psychology; Sialorrhea; Treatment Outcome | 2002 |
Pharmacotherapy of bipolar disorder: the role of atypical antipsychotics and experimental strategies.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Calcium Channel Blockers; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone | 2002 |
Safety in treating bipolar disorder.
Topics: Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Diabetes Mellitus; Dibenzothiazepines; Dyskinesias; Haloperidol; Humans; Hyperglycemia; Hyperprolactinemia; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone; Thioridazine; Weight Gain | 2003 |
Pharmacological approaches to the management of schizophrenia.
Topics: Amisulpride; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone; Schizophrenia; Sulpiride | 2003 |
Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Donepezil; Fatty Acids, Omega-3; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Lamotrigine; Lithium Carbonate; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Risperidone; Thiazoles; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2003 |
[Late schizophrenia].
Topics: Adult; Age of Onset; Aged; Antipsychotic Agents; Chlorpromazine; Clozapine; Diagnostic and Statistical Manual of Mental Disorders; Electroconvulsive Therapy; Haloperidol; Humans; Middle Aged; Reference Standards; Risk Factors; Risperidone; Schizophrenia; Schizophrenic Psychology | 2003 |
An integrated analysis of acute treatment-emergent extrapyramidal syndrome in patients with schizophrenia during olanzapine clinical trials: comparisons with placebo, haloperidol, risperidone, or clozapine.
Topics: Acute Disease; Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Cholinergic Antagonists; Clozapine; Double-Blind Method; Female; Haloperidol; Humans; Male; Olanzapine; Pirenzepine; Placebos; Randomized Controlled Trials as Topic; Retrospective Studies; Risperidone; Schizophrenia | 2003 |
Antipsychotic medication and seizures: a review.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Quinolones; Risperidone; Seizures; Thiazoles | 2003 |
Diabetes mellitus associated with atypical anti-psychotic medications.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Clozapine; Diabetes Mellitus; Humans; Hyperglycemia; Middle Aged; Odds Ratio; Olanzapine; Risperidone | 2003 |
Pharmacologic management of psychosis in the elderly: a critical review.
Topics: Aged; Alzheimer Disease; Benzodiazepines; Bipolar Disorder; Clozapine; Depressive Disorder; Drug Administration Schedule; Humans; Lewy Body Disease; Olanzapine; Parkinson Disease; Pirenzepine; Psychotic Disorders; Risperidone | 2003 |
[The appearance of metabolic syndrome in treatment with atypical antipsychotics].
Topics: Adolescent; Adult; Age Factors; Aged; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Body Weight; Clinical Trials as Topic; Clozapine; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dibenzothiazepines; Female; Glucose; Haloperidol; Humans; Intellectual Disability; Male; Mental Disorders; Metabolic Syndrome; Middle Aged; Olanzapine; Quetiapine Fumarate; Retrospective Studies; Risk Factors; Risperidone; Schizophrenia; Sex Factors; Time Factors; Weight Gain | 2003 |
Atypical antipsychotics and new onset diabetes mellitus. An overview of the literature.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Diabetes Mellitus; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Olanzapine; Quetiapine Fumarate; Risk; Risperidone; Schizophrenia | 2004 |
Atypical antipsychotics: pharmacokinetics, therapeutic drug monitoring and pharmacological interactions.
Topics: Antipsychotic Agents; Benzodiazepines; Chemistry, Pharmaceutical; Clinical Trials as Topic; Clozapine; Cytochrome P-450 Enzyme System; Dibenzothiazepines; Drug Interactions; Drug Monitoring; Humans; Molecular Structure; Olanzapine; Piperazines; Quetiapine Fumarate; Risperidone; Schizophrenia; Thiazoles | 2004 |
A critical review of atypical antipsychotic utilization: comparing monotherapy with polypharmacy and augmentation.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Cyclohexanecarboxylic Acids; Drug Utilization; Gabapentin; gamma-Aminobutyric Acid; Humans; Polypharmacy; Risperidone; Schizophrenia; Valproic Acid | 2004 |
Naturalistic studies of second generation antipsychotics in the treatment of schizophrenia.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Patient Compliance; Piperazines; Polypharmacy; Quetiapine Fumarate; Quinolones; Research Design; Risperidone; Schizophrenia; Thiazoles; Treatment Outcome | 2004 |
[Dementia induced by antipsychotic drugs].
Topics: Antipsychotic Agents; Butyrophenones; Clozapine; Dementia; Diagnostic and Statistical Manual of Mental Disorders; Diagnostic Imaging; Humans; Phenothiazines; Risperidone; Xanthines | 2004 |
Antipsychotic-induced rabbit syndrome: epidemiology, management and pathophysiology.
Topics: Animals; Antipsychotic Agents; Clozapine; Diagnosis, Differential; Dyskinesia, Drug-Induced; Humans; Rabbits; Risperidone | 2004 |
[Current pharmacotherapy of schizophrenia].
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Piperazines; Quetiapine Fumarate; Risperidone; Schizophrenia; Serotonin Antagonists; Sulpiride; Thiazoles | 2004 |
Atypical antipsychotics in the treatment of children and adolescents: clinical applications.
Topics: Adolescent; Age Factors; Antipsychotic Agents; Attention Deficit and Disruptive Behavior Disorders; Benzodiazepines; Bipolar Disorder; Child; Child Development Disorders, Pervasive; Clozapine; Dibenzothiazepines; Humans; Mental Disorders; Olanzapine; Piperazines; Quetiapine Fumarate; Risperidone; Schizophrenia; Thiazoles; Tic Disorders | 2004 |
Atypical antipsychotics and diabetes mellitus: an association.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Diabetes Mellitus; Diabetic Ketoacidosis; Female; Glucose; Humans; Male; Olanzapine; Risperidone; Schizophrenia | 2004 |
Tardive dyskinesia rates with atypical antipsychotics in older adults.
Topics: Adult; Age Factors; Aged; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Administration Schedule; Dyskinesia, Drug-Induced; Humans; Incidence; Middle Aged; Olanzapine; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Schizophrenia | 2004 |
Obsessive-compulsive symptoms associated with clozapine and risperidone treatment: three case reports and review of the literature.
Topics: Adult; Antipsychotic Agents; Clozapine; Humans; Male; Obsessive-Compulsive Disorder; Risperidone; Schizophrenia; Treatment Outcome | 2004 |
Lewy body dementia: the litmus test for neuroleptic sensitivity and extrapyramidal symptoms.
Topics: Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clozapine; Controlled Clinical Trials as Topic; Dibenzothiazepines; Humans; Lewy Body Disease; Olanzapine; Parkinson Disease; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Treatment Outcome | 2004 |
[Psychotropics and weight gain].
Topics: Adolescent; Adult; Amisulpride; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Body Mass Index; Child; Clozapine; Dibenzothiazepines; Double-Blind Method; Female; Fructose; Haloperidol; Humans; Imidazoles; Indoles; Male; Obesity; Olanzapine; Piperazines; Placebos; Psychotropic Drugs; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Socioeconomic Factors; Sulpiride; Thiazoles; Time Factors; Topiramate; Valproic Acid; Weight Gain | 2004 |
Prevalence and outcomes of pharmaceutical industry-sponsored clinical trials involving clozapine, risperidone, or olanzapine.
Topics: Benzodiazepines; Clinical Trials as Topic; Clozapine; Drug Industry; Humans; Olanzapine; Outcome Assessment, Health Care; Psychotic Disorders; Risperidone | 2004 |
The promise of atypical antipsychotics: fewer side effects mean enhanced compliance and improved functioning.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Diabetes Mellitus, Type 2; Dibenzothiazepines; Drug Administration Schedule; Humans; Hyperprolactinemia; Mental Disorders; Olanzapine; Patient Compliance; Piperazines; Practice Guidelines as Topic; Prescription Fees; Quetiapine Fumarate; Quinolones; Risk Assessment; Risperidone; Thiazoles; Torsades de Pointes; Treatment Outcome; Weight Gain | 2004 |
Dopamine receptor microdomains involved in molecular recognition and the regulation of drug affinity and function.
Topics: Animals; Arginine; Aspartic Acid; Binding Sites; Clozapine; Dopamine; Dopamine Antagonists; Haloperidol; Humans; Ligands; Protein Structure, Tertiary; Receptors, Dopamine; Risperidone; Serine | 2004 |
Pharmacology of antipsychotics in the elderly: a focus on atypicals.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Piperazines; Psychotic Disorders; Quetiapine Fumarate; Quinolones; Risperidone; Serotonin Antagonists; Thiazoles; Treatment Outcome; United States | 2004 |
Optimizing atypical antipsychotic treatment strategies in the elderly.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Controlled Clinical Trials as Topic; Dementia; Dibenzothiazepines; Humans; Olanzapine; Parkinson Disease; Piperazines; Psychotic Disorders; Quetiapine Fumarate; Quinolones; Risperidone; Thiazoles; Treatment Outcome | 2004 |
Schizophrenia.
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Cognitive Behavioral Therapy; Dibenzothiepins; Haloperidol; Humans; Olanzapine; Patient Compliance; Perazine; Pimozide; Risperidone; Schizophrenia; Sulpiride | 2003 |
An analysis of the effect of funding source in randomized clinical trials of second generation antipsychotics for the treatment of schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Double-Blind Method; Drug Industry; Humans; Olanzapine; Piperazines; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Research Support as Topic; Retrospective Studies; Risperidone; Schizophrenia; Thiazoles; Treatment Outcome | 2004 |
Emerging evidence for the use of atypical antipsychotics in borderline personality disorder.
Topics: Antipsychotic Agents; Benzodiazepines; Borderline Personality Disorder; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Psychiatric Status Rating Scales; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Research Design; Risperidone | 2005 |
The role of second-generation antipsychotic monotherapy in the rapid control of acute bipolar mania.
Topics: Acute Disease; Anticonvulsants; Antipsychotic Agents; Aripiprazole; Basal Ganglia Diseases; Benzodiazepines; Bipolar Disorder; Clozapine; Dibenzothiazepines; Double-Blind Method; Humans; Lithium; Olanzapine; Piperazines; Placebos; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Treatment Outcome | 2005 |
A meta-analysis of neuropsychological change to clozapine, olanzapine, quetiapine, and risperidone in schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; MEDLINE; Neuropsychological Tests; Olanzapine; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2005 |
Toxicology and overdose of atypical antipsychotic medications in children: does newer necessarily mean safer?
Topics: Antipsychotic Agents; Aripiprazole; Basal Ganglia Diseases; Benzodiazepines; Cardiomyopathies; Child; Clozapine; Diabetes Mellitus; Dibenzothiazepines; Drug Interactions; Drug Overdose; Dry Eye Syndromes; Humans; Hyperlipidemias; Hypotension; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Seizures; Thiazoles | 2005 |
Schizophrenia.
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Haloperidol; Humans; Olanzapine; Patient Compliance; Perazine; Pimozide; Risperidone; Schizophrenia; Sulpiride | 2004 |
A typical mood stabilizers: a "typical role for atypical antipsychotics.
Topics: Affect; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disorder; Clozapine; Dibenzothiazepines; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Secondary Prevention; Sulpiride; Thiazoles | 2005 |
The impact of atypical antipsychotic medications on long-term memory dysfunction in schizophrenia spectrum disorder: a quantitative review.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Memory Disorders; Olanzapine; Retention, Psychology; Risperidone; Schizophrenia | 2006 |
Management options for bipolar disorder in children and adolescents.
Topics: Adolescent; Benzodiazepines; Bipolar Disorder; Carbamazepine; Child; Clozapine; Dibenzothiazepines; Humans; Lithium; Olanzapine; Quetiapine Fumarate; Risperidone; Valproic Acid | 2005 |
Antipsychotic poisoning in young children: a systematic review.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Child; Child, Preschool; Chlorpromazine; Clozapine; Dibenzothiazepines; Haloperidol; Humans; Infant; Infant, Newborn; Olanzapine; Pimozide; Piperazines; Poisoning; Quetiapine Fumarate; Quinolones; Risperidone | 2005 |
Tardive dyskinesia in the era of typical and atypical antipsychotics. Part 2: Incidence and management strategies in patients with schizophrenia.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Dibenzothiazepines; Dyskinesia, Drug-Induced; Humans; Incidence; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Thiazoles | 2005 |
A systematic review of the efficacy and safety of second generation antipsychotics in the treatment of mania.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Piperazines; Quetiapine Fumarate; Risperidone; Thiazoles; Treatment Outcome | 2006 |
[Mechanisms of the body weight gain induced by novel antipsychotic drugs and concomitant lipid abnormalities].
Topics: Antipsychotic Agents; Body Weight; Clozapine; Dibenzothiazepines; Humans; Hyperlipidemias; Leptin; Piperazines; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Thiazoles; Weight Gain | 2005 |
Schizophrenia.
Topics: Amisulpride; Antipsychotic Agents; Chlorpromazine; Clozapine; Cognitive Behavioral Therapy; Dibenzothiepins; Family Therapy; Haloperidol; Humans; Patient Compliance; Risperidone; Schizophrenia; Secondary Prevention; Sulpiride; Thioridazine | 2005 |
[Autistic disorder: current psychopharmacological treatments and areas of interest for future developments].
Topics: Antidepressive Agents; Antipsychotic Agents; Autistic Disorder; Clinical Trials as Topic; Clozapine; Humans; Placebos; Risperidone | 2006 |
Risperidone augmentation of clozapine: a critical review.
Topics: Antipsychotic Agents; Clozapine; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans; Psychotic Disorders; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Schizophrenic Psychology; Sialorrhea; Treatment Outcome | 2006 |
Clinical trial-based cost-effectiveness analyses of antipsychotic use.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cost-Benefit Analysis; Costs and Cost Analysis; Drug Costs; Health Care Costs; Humans; Olanzapine; Patient Dropouts; Randomized Controlled Trials as Topic; Reproducibility of Results; Research Design; Resource Allocation; Risperidone; Schizophrenia; Treatment Outcome | 2006 |
Treatment of psychosis: 30 years of progress.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Piperazines; Psychotic Disorders; Quetiapine Fumarate; Quinolones; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Schizophrenia; Thiazoles | 2006 |
[The use of atypical antipsychotics in the long-term care of schizophrenia].
Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Basal Ganglia Diseases; Benzodiazepines; Clozapine; Cognition Disorders; Drug Tolerance; Dyskinesia, Drug-Induced; Haloperidol; Humans; Olanzapine; Piperazines; Quinolones; Risperidone; Schizophrenia; Sulpiride; Time Factors | 2006 |
The management of psychosis in movement disorder patients.
Topics: Antipsychotic Agents; Clozapine; Haloperidol; Humans; Huntington Disease; Lewy Body Disease; Parkinson Disease; Patient Education as Topic; Psychotic Disorders; Risperidone | 2007 |
Atypical antipsychotics: new drugs, new challenges.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Diabetes Mellitus; Humans; Olanzapine; Psychotic Disorders; Risk Factors; Risperidone; Weight Gain | 2007 |
Metabolic effects of the atypical antipsychotics.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Diabetes Mellitus; Dibenzothiazepines; Dyslipidemias; Glucose Metabolism Disorders; Humans; Insulin Resistance; Mental Disorders; Obesity; Olanzapine; Phenothiazines; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Thiazoles | 2007 |
Augmentation of antidepressants with atypical antipsychotics: a review of the current literature.
Topics: Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Clozapine; Depressive Disorder, Major; Dibenzothiazepines; Drug Synergism; Drug Therapy, Combination; Humans; Olanzapine; Piperazines; Quetiapine Fumarate; Risperidone; Thiazoles | 2008 |
Atypical antipsychotics in children and adolescents with autistic and other pervasive developmental disorders.
Topics: Adolescent; Aggression; Antipsychotic Agents; Aripiprazole; Autistic Disorder; Benzodiazepines; Child; Child Development Disorders, Pervasive; Child, Preschool; Clozapine; Dibenzothiazepines; Disorders of Excessive Somnolence; Humans; Obesity; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Thiazoles | 2008 |
Neuroleptic malignant syndrome associated with atypical antipsychotics in pediatric patients: a review of published cases.
Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disorder; Child; Child, Preschool; Clozapine; Dibenzothiazepines; Humans; Neuroleptic Malignant Syndrome; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Retrospective Studies; Risperidone; Thiazoles | 2008 |
[Atypical antipsychotics in first-episode psychosis: a review].
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Severity of Illness Index | 2008 |
HTR2C gene polymorphisms and the metabolic syndrome in patients with schizophrenia: a replication study.
Topics: Adult; Antipsychotic Agents; Clozapine; Cross-Sectional Studies; Female; Humans; Linkage Disequilibrium; Male; Metabolic Syndrome; Polymorphism, Genetic; Promoter Regions, Genetic; Receptor, Serotonin, 5-HT2C; Reverse Transcriptase Polymerase Chain Reaction; Risk; Risperidone; Schizophrenia; Treatment Outcome | 2009 |
Akathisia and second-generation antipsychotic drugs.
Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Isoxazoles; Olanzapine; Piperazines; Piperidines; Prevalence; Psychomotor Agitation; Psychotic Disorders; Quetiapine Fumarate; Quinolones; Risk Factors; Risperidone; Sulpiride; Thiazoles | 2009 |
Inflammation and the phenomenology, pathophysiology, comorbidity, and treatment of bipolar disorder: a systematic review of the literature.
Topics: Anti-Inflammatory Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Brief Psychiatric Rating Scale; Celecoxib; Clozapine; Comorbidity; Cytokines; Humans; Inflammation; Lithium Carbonate; Pyrazoles; Risperidone; Sulfonamides; Surveys and Questionnaires; Treatment Outcome | 2009 |
Clozapine combined with different antipsychotic drugs for treatment resistant schizophrenia.
Topics: Amisulpride; Antipsychotic Agents; Clozapine; Dibenzothiazepines; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Piperazines; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Sulpiride; Thiazoles | 2009 |
Are weight gain and metabolic side effects of atypical antipsychotics dose dependent? A literature review.
Topics: Adolescent; Adult; Antipsychotic Agents; Child; Clozapine; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Insulin; Male; Metabolic Syndrome; Risperidone; Treatment Outcome; Triglycerides; Weight Gain | 2009 |
Ziprasidone versus other atypical antipsychotics for schizophrenia.
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Piperazines; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Sulpiride; Thiazoles | 2009 |
Quetiapine versus other atypical antipsychotics for schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Medication Adherence; Olanzapine; Piperazines; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Thiazoles | 2010 |
[Risk of type 2 diabetes mellitus among users of atypical antipsychotic drugs or conventional treatment: systematic review and meta-analysis].
Topics: Antipsychotic Agents; Chronic Disease; Clozapine; Diabetes Mellitus, Type 2; Humans; Mental Disorders; Risk Factors; Risperidone | 2009 |
Olanzapine versus other atypical antipsychotics for schizophrenia.
Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Sulpiride; Thiazoles | 2010 |
[Neuroleptic adverse effects with emphasis on weight gain].
Topics: Adolescent; Antipsychotic Agents; Benzodiazepines; Brain; Cardiomyopathies; Child; Clozapine; Dyskinesia, Drug-Induced; Energy Metabolism; Feeding Behavior; Female; Gene Expression; Genetic Association Studies; Humans; Male; Myocarditis; Olanzapine; Pericarditis; Risperidone; Tourette Syndrome; Twin Studies as Topic; Weight Gain | 2009 |
Antipsychotics in pregnancy.
Topics: Abnormalities, Drug-Induced; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Diabetes, Gestational; Dibenzothiazepines; Female; Humans; Infant, Newborn; Olanzapine; Piperazines; Pregnancy; Pregnancy Complications; Psychotic Disorders; Quetiapine Fumarate; Quinolones; Risperidone; Thiazoles | 2010 |
Differences in efficacy on substance abuse between risperidone and clozapine supports the importance of differential modulation of dopaminergic neurotransmission.
Topics: Antipsychotic Agents; Clozapine; Humans; Psychotic Disorders; Receptors, Dopamine D1; Receptors, Dopamine D2; Risperidone; Substance-Related Disorders | 2009 |
Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis.
Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Blood Glucose; Cholesterol; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Sulpiride; Thiazoles; Weight Gain | 2010 |
Management of hallucinations and psychosis in Parkinson's disease.
Topics: Aged; Antipsychotic Agents; Brief Psychiatric Rating Scale; Clozapine; Comorbidity; Delusions; Dementia; Depression; Dibenzothiazepines; Disease Progression; Guidelines as Topic; Hallucinations; Humans; Middle Aged; Parkinson Disease; Psychotic Disorders; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Research Report; Risperidone | 2010 |
Zotepine versus other atypical antipsychotics for schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Dibenzothiepins; Humans; Randomized Controlled Trials as Topic; Remoxipride; Risperidone; Schizophrenia | 2010 |
Clozapine versus other atypical antipsychotics for schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Humans; Olanzapine; Piperazines; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Thiazoles | 2010 |
Risperidone versus other atypical antipsychotics for schizophrenia.
Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Sulpiride; Thiazoles | 2011 |
Management of marked liver enzyme increase during olanzapine treatment: a case report and review of the literature.
Topics: Age Factors; Antipsychotic Agents; Benzodiazepines; Chemical and Drug Induced Liver Injury; Clozapine; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Liver; Middle Aged; Olanzapine; Perazine; Risk Factors; Risperidone; Transaminases | 2011 |
Clozapine resistance: augmentation strategies.
Topics: Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Risperidone; Schizophrenia | 2012 |
Mid-term and long-term efficacy and effectiveness of antipsychotic medications for schizophrenia: a data-driven, personalized clinical approach.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Combined Modality Therapy; Humans; Olanzapine; Patient Participation; Psychotherapy; Psychotic Disorders; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Time Factors; Treatment Outcome | 2011 |
Are there different neural mechanisms responsible for three stages of weight gain development in anti-psychotic therapy: temporally based hypothesis.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Nervous System Physiological Phenomena; Olanzapine; Psychotic Disorders; Risperidone; Time Factors; Weight Gain | 2012 |
Atypical antipsychotics for the treatment of disruptive behavior.
Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Attention Deficit and Disruptive Behavior Disorders; Benzodiazepines; Child; Clozapine; Dibenzothiazepines; Drug Interactions; Drug Monitoring; Humans; Olanzapine; Pediatrics; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone | 2013 |
Thrombotic complications of treatment with antipsychotic drugs.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Odds Ratio; Olanzapine; Risk Factors; Risperidone; Thrombosis; Venous Thromboembolism | 2013 |
The first-episode of schizophrenia: a challenge for treatment.
Topics: Age Factors; Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Medication Adherence; Olanzapine; Patient Education as Topic; Risperidone; Schizophrenia; Schizophrenic Psychology; Secondary Prevention; Treatment Outcome | 2002 |
Schizophrenia.
Topics: Antipsychotic Agents; Aripiprazole; Clozapine; Humans; Risperidone; Schizophrenia; Treatment Outcome | 2012 |
Quetiapine versus other atypical antipsychotics for schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Medication Adherence; Olanzapine; Piperazines; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Thiazoles | 2013 |
Individualizing clozapine and risperidone treatment for schizophrenia patients.
Topics: Clozapine; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmacogenetics; Precision Medicine; Risperidone; Schizophrenia; Treatment Outcome | 2014 |
A bibliometric study of scientific research conducted on second-generation antipsychotic drugs in Singapore.
Topics: Antipsychotic Agents; Benzodiazepines; Bibliometrics; Biomedical Research; Clozapine; Humans; Journal Impact Factor; Olanzapine; Publications; Risperidone; Singapore | 2014 |
Treating the violent patient with psychosis or impulsivity utilizing antipsychotic polypharmacy and high-dose monotherapy.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brain; Clozapine; Dibenzocycloheptenes; Drug Therapy, Combination; Heterocyclic Compounds, 4 or More Rings; Humans; Impulsive Behavior; Isoxazoles; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Polypharmacy; Psychotic Disorders; Quetiapine Fumarate; Receptors, Dopamine D2; Risperidone; Thiazoles; Violence | 2014 |
HTR2C polymorphisms, olanzapine-induced weight gain and antipsychotic-induced metabolic syndrome in schizophrenia patients: a meta-analysis.
Topics: Alleles; Antipsychotic Agents; Benzodiazepines; Clozapine; Female; Genetic Association Studies; Humans; Male; Metabolic Syndrome; Olanzapine; Polymorphism, Single Nucleotide; Receptor, Serotonin, 5-HT2C; Risperidone; Schizophrenia; Weight Gain | 2014 |
Treatment resistant schizophrenia: a comprehensive survey of randomised controlled trials.
Topics: Antipsychotic Agents; Clozapine; Cognitive Behavioral Therapy; Humans; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Treatment Failure | 2014 |
Efficacy, Acceptability, and Tolerability of Antipsychotics in Treatment-Resistant Schizophrenia: A Network Meta-analysis.
Topics: Adult; Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Clozapine; Double-Blind Method; Drug Resistance; Female; Haloperidol; Humans; Male; Middle Aged; Olanzapine; Patient Acceptance of Health Care; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Single-Blind Method; Treatment Outcome | 2016 |
Diabetic ketoacidosis in patients exposed to antipsychotics: a systematic literature review and analysis of Danish adverse drug event reports.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Blood Glucose; Clozapine; Denmark; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Olanzapine; Risk Factors; Risperidone; Young Adult | 2016 |
Clozapine combined with different antipsychotic drugs for treatment-resistant schizophrenia.
Topics: Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Clozapine; Dibenzothiazepines; Drug Resistance; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Piperazines; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Sulpiride; Thiazoles; Weight Gain | 2017 |
Evidence-Based Review of Pharmacotherapy Used for Parkinson's Disease Psychosis.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Evidence-Based Medicine; Humans; Olanzapine; Parkinson Disease; Piperazines; Piperidines; Practice Guidelines as Topic; Psychotic Disorders; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Thiazoles; Urea | 2017 |
Risperidone versus other antipsychotics for people with severe mental illness and co-occurring substance misuse.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Diagnosis, Dual (Psychiatry); Humans; Mental Disorders; Olanzapine; Patient Dropouts; Perphenazine; Piperazines; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Substance-Related Disorders; Thiazoles | 2018 |
Maximizing response to first-line antipsychotics in schizophrenia: a review focused on finding from meta-analysis.
Topics: Amisulpride; Antidepressive Agents; Antipsychotic Agents; Clozapine; Depression; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2019 |
Association of First- vs. Second-Generation Antipsychotics with Lipid Abnormalities in Individuals with Severe Mental Illness: A Systematic Review and Meta-Analysis.
Topics: Antipsychotic Agents; Clozapine; Humans; Lipids; Mental Disorders; Olanzapine; Risperidone | 2019 |
Men and women respond differently to antipsychotic drugs.
Topics: Antipsychotic Agents; Clozapine; Female; Humans; Male; Olanzapine; Psychoses, Substance-Induced; Psychotic Disorders; Risperidone; Schizophrenia; Sex Factors | 2020 |
Personalizing dosing of risperidone, paliperidone and clozapine using therapeutic drug monitoring and pharmacogenetics.
Topics: Antipsychotic Agents; Clozapine; Drug Administration Routes; Drug Monitoring; Humans; Paliperidone Palmitate; Pharmacogenetics; Precision Medicine; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia | 2020 |
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia.
Topics: Acute Disease; Administration, Oral; Antipsychotic Agents; Aripiprazole; Clozapine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Haloperidol; Humans; Imidazoles; Indoles; Isoxazoles; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles; Thiophenes | 2020 |
[Pharmacotherapy of schizophrenia].
Topics: Adult; Antipsychotic Agents; Clozapine; Humans; Olanzapine; Risperidone; Schizophrenia | 2020 |
Real-World Data on the Adverse Metabolic Effects of Second-Generation Antipsychotics and Their Potential Determinants in Adult Patients: A Systematic Review of Population-Based Studies.
Topics: Adult; Antipsychotic Agents; Clozapine; Humans; Olanzapine; Quetiapine Fumarate; Risperidone | 2021 |
Toward personalized medicine in schizophrenia: Genetics and epigenetics of antipsychotic treatment.
Topics: Antipsychotic Agents; Clozapine; Epigenesis, Genetic; Humans; Precision Medicine; Risperidone; Schizophrenia | 2021 |
Pharmacodynamic Interactions Between Ketamine and Psychiatric Medications Used in the Treatment of Depression: A Systematic Review.
Topics: Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Depression; Drug Interactions; Female; Haloperidol; Humans; Ketamine; Lithium; Male; Olanzapine; Psychotropic Drugs; Risperidone; Schizophrenia; Treatment Outcome | 2021 |
Atypical Antipsychotic Drugs in Dual Disorders: Current Evidence for Clinical Practice.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Female; Humans; Male; Mice; Olanzapine; Quetiapine Fumarate; Rats; Risperidone | 2022 |
Pharmacological Treatment of Early-Onset Schizophrenia: A Critical Review, Evidence-Based Clinical Guidance and Unmet Needs.
Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Haloperidol; Humans; Lurasidone Hydrochloride; Molindone; Olanzapine; Paliperidone Palmitate; Quality of Life; Quetiapine Fumarate; Risperidone; Schizophrenia; Systematic Reviews as Topic | 2022 |
Augmentation strategies for clozapine resistance: a systematic review and meta-analysis.
Topics: Antipsychotic Agents; Clozapine; Humans; Mirtazapine; Risperidone; Schizophrenia | 2023 |
Anti-inflammatory effects of 2nd generation antipsychotics in patients with schizophrenia: A systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents; Antipsychotic Agents; Benzodiazepines; Clozapine; Cytokines; Humans; Olanzapine; Risperidone; Schizophrenia | 2023 |
Clozapine augmentation with long-acting antipsychotic injections: A case series and systematic review.
Topics: Antipsychotic Agents; Clozapine; Delayed-Action Preparations; Humans; Paliperidone Palmitate; Risperidone; Schizophrenia | 2023 |
83 trial(s) available for risperidone and clozapine
| Article | Year |
|---|---|
Risperidone versus clozapine in the treatment of schizophrenic patients with acute symptoms: a double blind, randomized trial.
Topics: Acute Disease; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Double-Blind Method; Electrocardiography; Electroencephalography; Female; Humans; Infant, Newborn; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia, Paranoid | 1994 |
Risperidone and clozapine in the treatment of drug-resistant schizophrenia and neuroleptic-induced supersensitivity psychosis.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Resistance; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Psychoses, Substance-Induced; Risperidone; Schizophrenia; Schizophrenic Psychology; Sex Characteristics | 1994 |
Randomized, double-blind, controlled trial of risperidone versus clozapine in patients with chronic schizophrenia.
Topics: Adult; Antipsychotic Agents; Clozapine; Double-Blind Method; Female; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1995 |
New pharmacotherapeutic modalities for negative symptoms in psychosis.
Topics: Affective Symptoms; Antipsychotic Agents; Clozapine; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Psychometrics; Risperidone; Schizophrenia; Schizophrenic Psychology; Syndrome | 1995 |
Different side effect profiles of risperidone and clozapine in 20 outpatients with schizophrenia or schizoaffective disorder: a pilot study.
Topics: Akathisia, Drug-Induced; Ambulatory Care; Clozapine; Cognition Disorders; Cross-Over Studies; Humans; Neuropsychological Tests; Pilot Projects; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology; Sleep; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 1996 |
Treatment-resistant schizophrenia: clinical experience with new antipsychotics.
Topics: Clozapine; Humans; Risperidone; Schizophrenia | 1996 |
Solid-phase extraction and high-performance liquid chromatographic analysis of clozapine and norclozapine in human plasma.
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Clozapine; Drug Interactions; Drug Monitoring; Humans; Risperidone; Verapamil | 1996 |
The prevalence of acute extrapyramidal signs and symptoms in patients treated with clozapine, risperidone, and conventional antipsychotics.
Topics: Acute Disease; Adolescent; Adult; Akathisia, Drug-Induced; Ambulatory Care; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Prevalence; Product Surveillance, Postmarketing; Psychotic Disorders; Risperidone; Schizophrenia; Severity of Illness Index | 1998 |
An open comparison of clozapine and risperidone in treatment-resistant schizophrenia.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Resistance; Female; Humans; Male; Psychiatric Status Rating Scales; Risperidone; Schizophrenia | 1998 |
Risperidone versus clozapine in treatment-resistant chronic schizophrenia: a randomized double-blind study. The Risperidone Study Group.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Chronic Disease; Clozapine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Treatment Failure; Treatment Outcome | 1998 |
The effects of risperidone and olanzapine on the indications for clozapine.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Olanzapine; Pirenzepine; Risperidone; Schizophrenia | 1998 |
Risperidone as an adjunct to clozapine therapy in chronic schizophrenics.
Topics: Adult; Ambulatory Care; Antipsychotic Agents; Chronic Disease; Clozapine; Drug Interactions; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1996 |
Clinical and neurocognitive effects of clozapine and risperidone in treatment-refractory schizophrenic patients: a prospective study.
Topics: Adult; Basal Ganglia Diseases; Clozapine; Cognition Disorders; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1998 |
Atypical antipsychotics.
Topics: Adolescent; Antipsychotic Agents; Benzodiazepines; Child; Clozapine; Female; Humans; Male; Olanzapine; Pirenzepine; Risperidone; Serotonin Antagonists | 1998 |
Clozapine and risperidone in chronic schizophrenia: effects on symptoms, parkinsonian side effects, and neuroendocrine response.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Chronic Disease; Clozapine; Double-Blind Method; Drug Administration Schedule; Female; Human Growth Hormone; Humans; Hydrocortisone; Male; Parkinson Disease, Secondary; Prolactin; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1999 |
Effects of atypical antipsychotic drug treatment on amphetamine-induced striatal dopamine release in patients with psychotic disorders.
Topics: Adult; Amphetamine; Antipsychotic Agents; Clozapine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Neostriatum; Psychotic Disorders; Raclopride; Risperidone; Salicylamides; Tomography, Emission-Computed | 1999 |
Novel antipsychotics: comparison of weight gain liabilities.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Double-Blind Method; Haloperidol; Humans; Imidazoles; Indoles; Male; Obesity; Olanzapine; Pirenzepine; Placebos; Retrospective Studies; Risperidone; Schizophrenia; Weight Gain | 1999 |
Antipsychotic drug effects on motor activation measured by functional magnetic resonance imaging in schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Clozapine; Female; Humans; Magnetic Resonance Imaging; Male; Motor Cortex; Oxygen; Psychomotor Performance; Risperidone; Schizophrenia; Somatosensory Cortex | 1999 |
Expected incidence of tardive dyskinesia associated with atypical antipsychotics.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Double-Blind Method; Drug Administration Schedule; Dyskinesia, Drug-Induced; Haloperidol; Humans; Incidence; Molindone; Olanzapine; Pirenzepine; Prospective Studies; Risk Factors; Risperidone; Schizophrenia; Substance Withdrawal Syndrome; Survival Analysis | 2000 |
Clozapine and risperidone treatment of psychosis in Parkinson's disease.
Topics: Aged; Antipsychotic Agents; Brief Psychiatric Rating Scale; Clozapine; Double-Blind Method; Humans; Middle Aged; Parkinson Disease; Psychotic Disorders; Risperidone | 2000 |
A naturalistic comparison of clozapine, risperidone, and olanzapine in the treatment of bipolar disorder.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Bipolar Disorder; Body Weight; Clozapine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lithium; Male; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Retrospective Studies; Risperidone; Treatment Outcome; Valproic Acid | 2000 |
Risperidone versus clozapine in treatment-resistant schizophrenia: a randomized pilot study.
Topics: Adult; Antipsychotic Agents; Clozapine; Female; Humans; Male; Middle Aged; Pilot Projects; Recurrence; Risperidone; Schizophrenia; Severity of Illness Index; Treatment Outcome | 2000 |
An open trial of risperidone augmentation of partial response to clozapine.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Risperidone; Schizophrenia | 2001 |
Safety and efficacy of risperidone in substance abusers with psychosis.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Psychotic Disorders; Risperidone; Substance-Related Disorders; Treatment Outcome | 2001 |
A double-blind comparative study of clozapine and risperidone in the management of severe chronic schizophrenia.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Chronic Disease; Clozapine; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Risk Factors; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Treatment Outcome | 2001 |
Effects of clozapine, olanzapine, risperidone, and haloperidol on hostility among patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Dose-Response Relationship, Drug; Double-Blind Method; Emotions; Female; Haloperidol; Hostility; Humans; Linear Models; Male; Olanzapine; Pirenzepine; Prospective Studies; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology; Statistics, Nonparametric; Survival Analysis | 2001 |
Neuroendocrine responsivities of the pituitary dopamine system in male schizophrenic patients during treatment with clozapine, olanzapine, risperidone, sulpiride, or haloperidol.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Pituitary Gland; Prolactin; Receptors, Dopamine D2; Risperidone; Schizophrenia; Sulpiride | 2001 |
Relationship between neuroleptic dosage and subjective cognitive dysfunction in schizophrenic patients treated with either conventional or atypical neuroleptic medication.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition Disorders; Dose-Response Relationship, Drug; Female; Humans; Male; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Surveys and Questionnaires | 2002 |
Clozapine, olanzapine, risperidone, and haloperidol in the treatment of patients with chronic schizophrenia and schizoaffective disorder.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clozapine; Double-Blind Method; Female; Haloperidol; Humans; Male; Middle Aged; Olanzapine; Patient Admission; Pirenzepine; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2002 |
Neurocognitive effects of clozapine, olanzapine, risperidone, and haloperidol in patients with chronic schizophrenia or schizoaffective disorder.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition; Double-Blind Method; Female; Haloperidol; Humans; Male; Neuropsychological Tests; Olanzapine; Pirenzepine; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2002 |
Classical and atypical neuroleptics, and bone mineral density, in patients with schizophrenia.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Bone Density; Clopenthixol; Clozapine; Female; Fluphenazine; Haloperidol; Humans; Male; Olanzapine; Pirenzepine; Risperidone; Schizophrenia | 2002 |
Therapeutic drug monitoring data: risperidone does not increase serum clozapine concentration.
Topics: Adolescent; Adult; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Humans; Male; Middle Aged; Risperidone; Smoking | 2002 |
Changes in glucose and cholesterol levels in patients with schizophrenia treated with typical or atypical antipsychotics.
Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Cholesterol; Clozapine; Double-Blind Method; Drug Administration Schedule; Female; Haloperidol; Hospitalization; Humans; Hypercholesterolemia; Hyperglycemia; Male; Middle Aged; Olanzapine; Pirenzepine; Prospective Studies; Psychotic Disorders; Risperidone; Schizophrenia; Weight Gain | 2003 |
A randomized evaluation of the effects of six antipsychotic agents on QTc, in the absence and presence of metabolic inhibition.
Topics: Adolescent; Adult; Antipsychotic Agents; Aryl Hydrocarbon Hydroxylases; Benzodiazepines; Biotransformation; Clozapine; Dibenzothiazepines; Electrocardiography; Female; Haloperidol; Heart Conduction System; Humans; Long QT Syndrome; Male; Middle Aged; Olanzapine; Quetiapine Fumarate; Risperidone; Thioridazine | 2004 |
Prolactin levels in schizophrenia and schizoaffective disorder patients treated with clozapine, olanzapine, risperidone, or haloperidol.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Haloperidol; Humans; Male; Olanzapine; Prolactin; Risperidone; Schizophrenia; Sexual Dysfunction, Physiological | 2004 |
Do clozapine and risperidone affect social competence and problem solving?
Topics: Adult; Clozapine; Cognition Disorders; Double-Blind Method; Female; Humans; Male; Neuropsychological Tests; Problem Solving; Risperidone; Schizophrenia; Severity of Illness Index; Social Behavior | 2004 |
Effects of atypical antipsychotics on the syndromal profile in treatment-resistant schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Double-Blind Method; Factor Analysis, Statistical; Female; Haloperidol; Humans; Male; Olanzapine; Prospective Studies; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2004 |
Overt aggression and psychotic symptoms in patients with schizophrenia treated with clozapine, olanzapine, risperidone, or haloperidol.
Topics: Aggression; Antipsychotic Agents; Benzodiazepines; Clozapine; Double-Blind Method; Haloperidol; Humans; Olanzapine; Psychiatric Status Rating Scales; Psychometrics; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology | 2004 |
Clozapine augmented with risperidone in the treatment of schizophrenia: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Antipsychotic Agents; Brief Psychiatric Rating Scale; Clozapine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Placebos; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2005 |
A double-blind controlled study of adjunctive treatment with risperidone in schizophrenic patients partially responsive to clozapine: efficacy and safety.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Humans; Placebos; Prolactin; Prospective Studies; Psychiatric Status Rating Scales; Quality of Life; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2005 |
The effects of clozapine and risperidone on spatial working memory in schizophrenia.
Topics: Adult; Antipsychotic Agents; Brief Psychiatric Rating Scale; Clozapine; Diagnosis, Computer-Assisted; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Memory; Memory Disorders; Middle Aged; Neuropsychological Tests; Prefrontal Cortex; Psychomotor Performance; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology; Space Perception | 2005 |
Clozapine improves working memory updating in schizophrenia.
Topics: Adult; Antipsychotic Agents; Biperiden; Clozapine; Electroencephalography; Evoked Potentials; Female; Humans; Male; Memory, Short-Term; Middle Aged; Muscarinic Antagonists; Neuropsychological Tests; Psychomotor Performance; Risperidone; Schizophrenia; Schizophrenic Psychology | 2005 |
Efficacy of clozapine, olanzapine, risperidone, and haloperidol in schizophrenia and schizoaffective disorder assessed with nurses observation scale for inpatient evaluation.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Double-Blind Method; Haloperidol; Humans; Nursing Assessment; Olanzapine; Prospective Studies; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2005 |
Effectiveness of clozapine, olanzapine, quetiapine, risperidone, and haloperidol monotherapy in reducing hostile and aggressive behavior in outpatients treated for schizophrenia: a prospective naturalistic study (IC-SOHO).
Topics: Adult; Aggression; Antipsychotic Agents; Benzodiazepines; Clozapine; Cohort Studies; Dibenzothiazepines; Female; Haloperidol; Hostility; Humans; Male; Olanzapine; Outpatients; Prospective Studies; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2005 |
Subjective response to clozapine and risperidone treatment in outpatients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Attitude; Chi-Square Distribution; Clozapine; Drug Therapy, Combination; Female; Humans; Male; Multivariate Analysis; Outpatients; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Surveys and Questionnaires; Time Factors | 2006 |
Clozapine alone versus clozapine and risperidone with refractory schizophrenia.
Topics: Adult; Antipsychotic Agents; Clozapine; Cognition; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Failure | 2006 |
Ambulatory use of olanzapine and risperidone: a population-based study on persistence and the use of concomitant therapy in the treatment of schizophrenia.
Topics: Adult; Aged; Ambulatory Care; Antipsychotic Agents; Benzodiazepines; Clozapine; Cohort Studies; Dibenzothiazepines; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Olanzapine; Population Surveillance; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Time Factors | 2005 |
Time to discontinuation of atypical versus typical antipsychotics in the naturalistic treatment of schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bias; Clozapine; Drug Administration Schedule; Episode of Care; Female; Follow-Up Studies; Humans; Male; Olanzapine; Outcome Assessment, Health Care; Perphenazine; Proportional Hazards Models; Research Design; Risperidone; Schizophrenia; Time Factors; Treatment Outcome; United States | 2006 |
Resource utilization in a Canadian national study of people with schizophrenia and related psychotic disorders.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Canada; Clozapine; Cohort Studies; Cost of Illness; Cost-Benefit Analysis; Dibenzothiazepines; Drug Costs; Female; Health Care Surveys; Health Resources; Humans; Male; Olanzapine; Prospective Studies; Psychotic Disorders; Quetiapine Fumarate; Risk Assessment; Risperidone; Schizophrenia | 2006 |
Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment.
Topics: Adult; Agranulocytosis; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clozapine; Cross-Over Studies; Dibenzothiazepines; Drug Monitoring; Drug Resistance; Eosinophilia; Female; Follow-Up Studies; Humans; Male; Olanzapine; Piperazines; Prospective Studies; Psychiatric Status Rating Scales; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles; Treatment Outcome | 2006 |
Effects of typical and atypical antipsychotics on glucose-insulin homeostasis and lipid metabolism in first-episode schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Body Mass Index; C-Peptide; Cholesterol; Clozapine; Female; Homeostasis; Humans; Insulin; Insulin Resistance; Lipid Metabolism; Male; Metabolic Syndrome; Olanzapine; Prospective Studies; Risperidone; Schizophrenia; Sulpiride; Triglycerides; Waist-Hip Ratio | 2006 |
Clinical drug monitoring in child and adolescent psychiatry: side effects of atypical neuroleptics.
Topics: Adolescent; Adolescent Psychiatry; Adult; Antipsychotic Agents; Benzodiazepines; Child; Child Psychiatry; Clozapine; Drug Monitoring; Female; Humans; Male; Mental Disorders; Olanzapine; Risperidone | 2006 |
Effect of adjunctive lamotrigine treatment on the plasma concentrations of clozapine, risperidone and olanzapine in patients with schizophrenia or bipolar disorder.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Drug Interactions; Female; Humans; Lamotrigine; Male; Middle Aged; Olanzapine; Risperidone; Schizophrenia; Triazines | 2006 |
A double-blind study of combination of clozapine with risperidone in patients with schizophrenia: effects on cognition.
Topics: Adult; Antipsychotic Agents; Attention; Clozapine; Cognition; Cognition Disorders; Double-Blind Method; Female; Humans; Male; Memory; Middle Aged; Prospective Studies; Quality of Life; Risperidone; Schizophrenia; Treatment Outcome | 2006 |
Risperidone augmentation for schizophrenia partially responsive to clozapine: a double-blind, placebo-controlled trial.
Topics: Adult; Antipsychotic Agents; Clozapine; Double-Blind Method; Female; Humans; Male; Mass Screening; Middle Aged; Prolactin; Risperidone; Schizophrenia | 2007 |
Effects of antipsychotic medications on psychosocial functioning in patients with chronic schizophrenia: findings from the NIMH CATIE study.
Topics: Adaptation, Psychological; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clozapine; Dibenzothiazepines; Follow-Up Studies; Health Status; Humans; National Institute of Mental Health (U.S.); Olanzapine; Patient Dropouts; Perphenazine; Piperazines; Quality of Life; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Social Adjustment; Thiazoles; Treatment Outcome; United States | 2007 |
Huperzine A as add-on therapy in patients with treatment-resistant schizophrenia: an open-labeled trial.
Topics: Adolescent; Adult; Aged; Alkaloids; Antipsychotic Agents; Chlorpromazine; Cholinesterase Inhibitors; Clozapine; Drug Resistance; Drug Synergism; Female; Humans; Male; Middle Aged; Risperidone; Schizophrenia; Sesquiterpenes | 2007 |
Double-blind donepezil-placebo crossover augmentation study of atypical antipsychotics in chronic, stable schizophrenia: a pilot study.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Cholinesterase Inhibitors; Clozapine; Cross-Over Studies; Donepezil; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Indans; Male; Middle Aged; Nootropic Agents; Olanzapine; Piperidines; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2007 |
A placebo-controlled add-on trial of the Ampakine, CX516, for cognitive deficits in schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition Disorders; Dioxoles; Double-Blind Method; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Olanzapine; Pilot Projects; Piperidines; Psychiatric Status Rating Scales; Psychomotor Performance; Risperidone; Sample Size; Schizophrenia; Schizophrenic Psychology | 2008 |
Neuroleptic treatment effect on mitochondrial electron transport chain: peripheral blood mononuclear cells analysis in psychotic patients.
Topics: Adult; Antipsychotic Agents; Clozapine; Cross-Sectional Studies; Electron Transport; Electron Transport Complex I; Female; Haloperidol; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Mitochondria; Neuroleptic Malignant Syndrome; Risperidone; Schizophrenia | 2007 |
Changes in neuroendocrine and metabolic hormones induced by atypical antipsychotics in normal-weight patients with schizophrenia.
Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Body Weight; Clozapine; Female; Ghrelin; Glucose Tolerance Test; Hormones; Human Growth Hormone; Humans; Insulin; Male; Metabolic Networks and Pathways; Neurosecretory Systems; Peptide Hormones; Risperidone; Schizophrenia; Weight Gain | 2007 |
Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment.
Topics: Antipsychotic Agents; Body Weight; Clozapine; Data Interpretation, Statistical; Double-Blind Method; Humans; Lipids; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; Triglycerides | 2007 |
Efficacy and tolerability of ziprasidone versus risperidone as augmentation in patients partially responsive to clozapine: a randomised controlled clinical trial.
Topics: Adolescent; Adult; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Female; Humans; Long QT Syndrome; Male; Middle Aged; Piperazines; Prolactin; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Thiazoles; Treatment Outcome; Young Adult | 2009 |
Decreased serum neurotrophin 3 in chronically medicated schizophrenic males.
Topics: Adult; Antipsychotic Agents; Clozapine; Diagnostic and Statistical Manual of Mental Disorders; Enzyme-Linked Immunosorbent Assay; Haloperidol; Humans; Longitudinal Studies; Male; Middle Aged; Neurotrophin 3; Phlebotomy; Risperidone; Schizophrenia | 2008 |
Treatment of psychotic disorders with aripiprazole in the emergency psychiatric setting.
Topics: Acute Disease; Adult; Antipsychotic Agents; Aripiprazole; Clozapine; Diagnostic and Statistical Manual of Mental Disorders; Dibenzothiazepines; Drug Therapy, Combination; Emergency Services, Psychiatric; Female; Humans; Intensive Care Units; Male; Middle Aged; Piperazines; Psychiatric Department, Hospital; Psychiatric Status Rating Scales; Psychotic Disorders; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Severity of Illness Index; Treatment Outcome | 2008 |
Results of phase 3 of the CATIE schizophrenia trial.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chronic Disease; Clozapine; Dibenzothiazepines; Female; Hospitalization; Humans; Male; Middle Aged; Olanzapine; Perphenazine; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Treatment Outcome; Young Adult | 2009 |
Neurocognitive effectiveness of haloperidol, risperidone, and olanzapine in first-episode psychosis: a randomized, controlled 1-year follow-up comparison.
Topics: Adult; Amisulpride; Antipsychotic Agents; Benzodiazepines; Brain; Clozapine; Cognition Disorders; Female; Follow-Up Studies; Haloperidol; Humans; Male; Neuropsychological Tests; Olanzapine; Perphenazine; Piperazines; Prospective Studies; Psychotic Disorders; Risperidone; Severity of Illness Index; Sulpiride; Thiazoles | 2009 |
The effect of antipsychotics on the high-affinity state of D2 and D3 receptors: a positron emission tomography study With [11C]-(+)-PHNO.
Topics: Adult; Antipsychotic Agents; Basal Ganglia; Benzodiazepines; Benzothiazoles; Binding, Competitive; Carbon Radioisotopes; Caudate Nucleus; Clozapine; Dopamine Agonists; Dopamine Antagonists; Double-Blind Method; Female; Globus Pallidus; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Olanzapine; Oxazines; Positron-Emission Tomography; Pramipexole; Putamen; Raclopride; Receptors, Dopamine D2; Receptors, Dopamine D3; Risperidone; Schizophrenia | 2009 |
Hunger and negative alliesthesia to aspartame and sucrose in patients treated with antipsychotic drugs and controls.
Topics: Adult; Antipsychotic Agents; Aspartame; Benzodiazepines; Carbonated Beverages; Clozapine; Dibenzothiazepines; Double-Blind Method; Food Preferences; Humans; Hunger; Male; Middle Aged; Olanzapine; Pleasure; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Schizophrenia; Sucrose; Surveys and Questionnaires; Sweetening Agents; Taste; Time Factors; Young Adult | 2009 |
Long-term efficacy and tolerability of clozapine combined with ziprasidone or risperidone.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Combination; Humans; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Risperidone; Serotonin Antagonists; Thiazoles; Time Factors; Treatment Outcome; Young Adult | 2010 |
Adjunctive risperidone for partially responsive people with schizophrenia treated with clozapine.
Topics: Adult; Clozapine; Double-Blind Method; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2010 |
Correlation of adenosinergic activity with superior efficacy of clozapine for treatment of chronic schizophrenia: a double blind randomised trial.
Topics: Adenosine; Adenosine Deaminase; Adult; Chronic Disease; Clozapine; Double-Blind Method; Female; Haloperidol; Humans; Male; Middle Aged; Prospective Studies; Risperidone; Schizophrenia; Treatment Outcome; Young Adult | 2011 |
An algorithm-based approach to first-episode schizophrenia: response rates over 3 prospective antipsychotic trials with a retrospective data analysis.
Topics: Adolescent; Adult; Algorithms; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Female; Humans; Male; Olanzapine; Prospective Studies; Quetiapine Fumarate; Retrospective Studies; Risperidone; Schizophrenia; Treatment Outcome; Young Adult | 2011 |
TNF-α -308 G>A polymorphism and weight gain in patients with schizophrenia under long-term clozapine, risperidone or olanzapine treatment.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Female; Genotype; Humans; Male; Middle Aged; Olanzapine; Polymorphism, Single Nucleotide; Prospective Studies; Risperidone; Schizophrenia; Single-Blind Method; Tumor Necrosis Factor-alpha; Weight Gain | 2011 |
Probabilistic classification and gambling in patients with schizophrenia receiving medication: comparison of risperidone, olanzapine, clozapine and typical antipsychotics.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Decision Making; Female; Gambling; Humans; Learning; Male; Middle Aged; Neuropsychological Tests; Olanzapine; Psychiatric Status Rating Scales; Risperidone; Schizophrenia | 2012 |
Choice of randomization to clozapine versus other second generation antipsychotics in the CATIE schizophrenia trial.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Double-Blind Method; Drug Resistance; Female; Humans; Male; Middle Aged; Olanzapine; Patient Acceptance of Health Care; Patient Dropouts; Patient Participation; Perphenazine; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Sex Characteristics | 2012 |
Clozapine and visuospatial processing in treatment-resistant schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition; Cognition Disorders; Dibenzothiazepines; Drug Resistance; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Olanzapine; Quetiapine Fumarate; Risperidone; Schizophrenia; Space Perception; Young Adult | 2013 |
Randomized trial of clozapine vs. risperidone in treatment-naïve first-episode schizophrenia: results after one year.
Topics: Adolescent; Adult; Antipsychotic Agents; Body Weight; Clozapine; Electrocardiography; Female; Follow-Up Studies; Glycemic Index; Humans; Lipid Metabolism; Male; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Time Factors; Treatment Outcome; Young Adult | 2013 |
The effect of clozapine and risperidone on attentional bias in patients with schizophrenia and a cannabis use disorder: An fMRI study.
Topics: Adolescent; Adult; Antipsychotic Agents; Attentional Bias; Brain Mapping; Clozapine; Craving; Humans; Magnetic Resonance Imaging; Male; Marijuana Abuse; Netherlands; Predictive Value of Tests; Risperidone; Schizophrenia; Schizophrenic Psychology; Stroop Test; Time Factors; Treatment Outcome; Young Adult | 2014 |
Comparative efficacy between clozapine and other atypical antipsychotics on depressive symptoms in patients with schizophrenia: analysis of the CATIE phase 2E data.
Topics: Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clozapine; Depressive Disorder, Major; Double-Blind Method; Olanzapine; Piperazines; Psychiatric Status Rating Scales; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles; Treatment Outcome | 2015 |
Clozapine and risperidone in moderately refractory schizophrenia: a 6-month randomized double-blind comparison.
Topics: Brief Psychiatric Rating Scale; Clozapine; Comorbidity; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Resistance; Humans; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2016 |
Comparing the effect of clozapine and risperidone on cue reactivity in male patients with schizophrenia and a cannabis use disorder: A randomized fMRI study.
Topics: Antipsychotic Agents; Brain; Brain Mapping; Clozapine; Comorbidity; Craving; Cues; Humans; Magnetic Resonance Imaging; Male; Marijuana Abuse; Medication Adherence; Risperidone; Schizophrenia; Treatment Outcome; Visual Perception; Young Adult | 2018 |
The validity and sensitivity of PANSS-6 in treatment-resistant schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Cross-Sectional Studies; Humans; Olanzapine; Outcome Assessment, Health Care; Psychiatric Status Rating Scales; Quetiapine Fumarate; Reproducibility of Results; Risperidone; Schizophrenia; Sensitivity and Specificity | 2018 |
627 other study(ies) available for risperidone and clozapine
| Article | Year |
|---|---|
Pyrrole mannich bases as potential antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Male; Mannich Bases; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship | 1992 |
Noncataleptogenic, centrally acting dopamine D-2 and serotonin 5-HT2 antagonists within a series of 3-substituted 1-(4-fluorophenyl)-1H-indoles.
Topics: Animals; Antipsychotic Agents; Dopamine Antagonists; Imidazoles; Indoles; Male; Mice; Piperazines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship | 1992 |
Synthesis and biological evaluation of a series of substituted N-alkoxyimides and -amides as potential atypical antipsychotic agents.
Topics: Amides; Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Catalepsy; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Imides; Male; Mice; Molecular Structure; Motor Activity; Phthalimides; Piperazines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Self Stimulation; Social Behavior; Spiro Compounds; Stereotyped Behavior; Thiazoles | 1991 |
3-[[(Aryloxy)alkyl]piperidinyl]-1,2-benzisoxazoles as D2/5-HT2 antagonists with potential atypical antipsychotic activity: antipsychotic profile of iloperidone (HP 873).
Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Dopamine Antagonists; In Vitro Techniques; Isoxazoles; Male; Piperidines; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship | 1995 |
Binding of 5H-dibenzo[a,d]cycloheptene and dibenz[b,f]oxepin analogues of clozapine to dopamine and serotonin receptors.
Topics: Binding Sites; Clozapine; Dibenzocycloheptenes; Dibenzoxepins; Humans; Receptors, Dopamine; Receptors, Serotonin | 1995 |
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin | 1994 |
Benzisoxazole- and benzisothiazole-3-carboxamides as potential atypical antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Isoxazoles; Male; Mice; Rats; Rats, Wistar; Stereotyped Behavior; Structure-Activity Relationship; Thiazoles | 1994 |
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity | 1996 |
3-Benzisothiazolylpiperazine derivatives as potential atypical antipsychotic agents.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Brain; Catalepsy; Clozapine; Dopamine; Drug Design; Humans; Molecular Structure; Phosphatidylinositols; Piperazines; Prazosin; Rats; Receptors, Adrenergic; Receptors, Dopamine; Serotonin Antagonists; Thiazoles | 1996 |
7-[3-(1-piperidinyl)propoxy]chromenones as potential atypical antipsychotics.
Topics: Administration, Oral; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Biological Availability; Catalepsy; Chromones; Male; Mice; Molecular Structure; Motor Activity; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Structure-Activity Relationship | 1996 |
Structure-activity relationships of a series of novel (piperazinylbutyl)thiazolidinone antipsychotic agents related to 3-[4-[4-(6-fluorobenzo[b]thien-3-yl)-1-piperazinyl]butyl]-2,5,5- trimethyl-4-thiazolidinone maleate.
Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Binding, Competitive; Cell Line; CHO Cells; Cricetinae; Humans; Male; Molecular Structure; Motor Activity; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Serotonin; Spiperone; Spiro Compounds; Stereotyped Behavior; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1996 |
Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding.
Topics: Animals; Antipsychotic Agents; Brain; Cells, Cultured; Clozapine; Haloperidol; Humans; Male; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Risperidone | 1996 |
Synthesis and evaluation of heterocyclic carboxamides as potential antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Apomorphine; Benzamides; Clozapine; Heterocyclic Compounds; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Piperazines; Raclopride; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Salicylamides; Thiazoles | 1996 |
Iloperidone binding to human and rat dopamine and 5-HT receptors.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; CHO Cells; Cricetinae; Humans; Isoxazoles; Kinetics; Piperidines; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Dopamine D4; Receptors, Dopamine D5; Receptors, Serotonin | 1996 |
Orally active benzamide antipsychotic agents with affinity for dopamine D2, serotonin 5-HT1A, and adrenergic alpha1 receptors.
Topics: Adrenergic Agents; Animals; Antipsychotic Agents; Avoidance Learning; Catalepsy; Cerebral Cortex; Conditioning, Psychological; Corpus Striatum; Dopamine Agents; Humans; Male; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Structure-Activity Relationship | 1998 |
Creation of a constitutively activated state of the 5-hydroxytryptamine2A receptor by site-directed mutagenesis: inverse agonist activity of antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; COS Cells; Mutagenesis, Site-Directed; Phosphatidylinositols; Protein Conformation; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship | 1998 |
Functional characterisation of the human cloned 5-HT7 receptor (long form); antagonist profile of SB-258719.
Topics: Adenylyl Cyclases; Cell Line; Cloning, Molecular; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Piperidines; Protein Binding; Receptors, Serotonin; Recombinant Proteins; Serotonin Antagonists; Sulfonamides | 1998 |
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes | 1998 |
7-[3-(1-piperidinyl)propoxy]chromenones as potential atypical antipsychotics. 2. Pharmacological profile of 7-[3-[4-(6-fluoro-1, 2-benzisoxazol-3-yl)-piperidin-1-yl]propoxy]-3-(hydroxymeth yl)chromen -4-one (abaperidone, FI-8602).
Topics: Administration, Oral; Animals; Antipsychotic Agents; Brain; Catalepsy; Cell Line; Chromones; Drug Evaluation, Preclinical; Guinea Pigs; Humans; Isoxazoles; Male; Mice; Motor Activity; Prolactin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Stereotyped Behavior; Structure-Activity Relationship | 1998 |
Conformationally constrained butyrophenones with mixed dopaminergic (D(2)) and serotoninergic (5-HT(2A), 5-HT(2C)) affinities: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and -thienocycloalkanones as putative atypical an
Topics: Animals; Antipsychotic Agents; Aorta, Thoracic; Brain; Catalepsy; Cattle; Dopamine Agents; In Vitro Techniques; Isoxazoles; Male; Mice; Models, Molecular; Motor Activity; Muscle Contraction; Muscle, Smooth, Vascular; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin Agents; Structure-Activity Relationship; Thiophenes | 1999 |
N-Substituted (2,3-dihydro-1,4-benzodioxin-2-yl)methylamine derivatives as D(2) antagonists/5-HT(1A) partial agonists with potential as atypical antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Brain; Catalepsy; Dioxanes; Dopamine Antagonists; Drug Evaluation, Preclinical; Humans; In Vitro Techniques; Male; Mice; Motor Activity; Piperidines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Proteins; Serotonin Receptor Agonists; Stereoisomerism; Stereotyped Behavior; Structure-Activity Relationship; Swine | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors.
Topics: Animals; Antipsychotic Agents; COS Cells; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Receptor Agonists | 2000 |
Conformationally constrained butyrophenones with affinity for dopamine (D(1), D(2), D(4)) and serotonin (5-HT(2A), 5-HT(2B), 5-HT(2C)) receptors: synthesis of aminomethylbenzo[b]furanones and their evaluation as antipsychotics.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Binding, Competitive; Butyrophenones; Catalepsy; Cattle; Corpus Striatum; Frontal Lobe; Humans; In Vitro Techniques; Isoxazoles; Male; Mice; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Serotonin; Retina | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Affinity of serotonin receptor antagonists and agonists to recombinant and native alpha1-adrenoceptor subtypes.
Topics: Animals; Aorta, Thoracic; Carotid Arteries; Dogs; Humans; Male; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
New 1-aryl-4-(biarylmethylene)piperazines as potential atypical antipsychotics sharing dopamine D(2)-receptor and serotonin 5-HT(1A)-receptor affinities.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Benzoxazoles; Dopamine Antagonists; Drug Design; Drug Evaluation, Preclinical; Mice; Piperazines; Rats; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Spiperone; Structure-Activity Relationship | 2001 |
New serotonin 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptor antagonists: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones.
Topics: Animals; Aorta; Butyrophenones; CHO Cells; Cricetinae; Cycloparaffins; Frontal Lobe; Heterocyclic Compounds; Humans; In Vitro Techniques; Ligands; Male; Models, Molecular; Muscle, Smooth, Vascular; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Stomach | 2002 |
In vitro P-glycoprotein affinity for atypical and conventional antipsychotics.
Topics: Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzodiazepines; Binding, Competitive; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Humans; Kinetics; Olanzapine; Pirenzepine; Quetiapine Fumarate; Recombinant Proteins; Risperidone | 2002 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2002 |
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain | 2003 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Chemoenzymatic synthesis and binding affinity of novel (R)- and (S)-3-aminomethyl-1-tetralones, potential atypical antipsychotics.
Topics: Antipsychotic Agents; Binding Sites; Haloperidol; Lipase; Pseudomonas fluorescens; Receptors, Dopamine D2; Receptors, Serotonin; Stereoisomerism; Tetralones | 2004 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
A two-state homology model of the hERG K+ channel: application to ligand binding.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation | 2005 |
Discovery of new tetracyclic tetrahydrofuran derivatives as potential broad-spectrum psychotropic agents.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Furans; Heterocyclic Compounds, 4 or More Rings; Humans; In Vitro Techniques; Mice; Psychotropic Drugs; Radioligand Assay; Rats; Stereoisomerism; Structure-Activity Relationship | 2005 |
Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs.
Topics: Amino Acid Substitution; Antipsychotic Agents; Cell Line; Cyclic AMP; Humans; Mutagenesis, Site-Directed; Mutation; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
From the Cover: Antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinase.
Topics: Adenylate Kinase; Animals; Antipsychotic Agents; Enzyme Activation; Hypothalamus; Immunohistochemistry; Mice; Phosphorylation; Receptors, Histamine H1; Weight Gain | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Synthesis and binding affinity of new pyrazole and isoxazole derivatives as potential atypical antipsychotics.
Topics: Antipsychotic Agents; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen Bonding; Isoxazoles; Kinetics; Models, Chemical; Molecular Conformation; Protein Binding; Pyrazoles; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D2; Software | 2007 |
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzoxazines; Biogenic Monoamines; Humans; Hyperprolactinemia; Indoles; Metabolic Diseases; Phthalimides; Piperazines; Principal Component Analysis; Pyridines; Radioligand Assay; Receptors, Biogenic Amine; Weight Gain | 2007 |
BK Virus replication in vitro: limited effect of drugs interfering with viral uptake and intracellular transport.
Topics: Antiviral Agents; BK Virus; Cell Line; Chloroquine; Humans; Microbial Sensitivity Tests; Molecular Structure; Nystatin; Virus Replication | 2007 |
Asenapine: a novel psychopharmacologic agent with a unique human receptor signature.
Topics: Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Cloning, Molecular; Clozapine; Dibenzocycloheptenes; Heterocyclic Compounds, 4 or More Rings; Histamine Release; Humans; Inhibitory Concentration 50; Molecular Structure; Olanzapine; Psychotropic Drugs; Radioligand Assay; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Muscarinic; Receptors, Serotonin; Schizophrenia; Substrate Specificity | 2009 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Identification of a butyrophenone analog as a potential atypical antipsychotic agent: 4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one.
Topics: Animals; Antipsychotic Agents; Apomorphine; Azepines; Butyrophenones; Clozapine; Haloperidol; Lethal Dose 50; Male; Mice; Molecular Structure; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors: design, synthesis, and effects on behavior.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Binding Sites; Drug Design; Drug Evaluation, Preclinical; Humans; Ligands; Mice; Models, Molecular; Molecular Structure; Protein Binding; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D3; Structure-Activity Relationship | 2009 |
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship | 2009 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Synthesis and evaluation of 1-(quinoliloxypropyl)-4-aryl piperazines for atypical antipsychotic effect.
Topics: Animals; Antipsychotic Agents; Mice; Oxyquinoline; Schizophrenia; Stereotyped Behavior | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers.
Topics: Binding Sites; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Potassium Channel Blockers; Protein Binding; Protein Conformation | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif.
Topics: Animals; Antipsychotic Agents; Blood-Brain Barrier; CHO Cells; Cricetinae; Cricetulus; Humans; Quinazolinones; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Schizophrenia | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Novel 7-phenylsulfanyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indoles as dual serotonin 5-HT2C and 5-HT6 receptor ligands.
Topics: Cell Line; HeLa Cells; Humans; Indoles; Ligands; Protein Binding; Pyrazines; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results | 2011 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Molecular properties affecting fast dissociation from the D2 receptor.
Topics: Antipsychotic Agents; Dopamine D2 Receptor Antagonists; Drug Administration Schedule; Drug Design; Humans; Molecular Structure; Receptors, Dopamine D2; Structure-Activity Relationship | 2011 |
Microdialysis evaluation of clozapine and N-desmethylclozapine pharmacokinetics in rat brain.
Topics: Animals; Antipsychotic Agents; Biotransformation; Blood-Brain Barrier; Brain; Clozapine; Injections, Subcutaneous; Male; Microdialysis; Models, Biological; Permeability; Rats; Rats, Wistar | 2012 |
Current landscape of phosphodiesterase 10A (PDE10A) inhibition.
Topics: Animals; Cyclic AMP; Cyclic GMP; Humans; Hydrolysis; Mice; Models, Molecular; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
Synthesis and biological investigation of coumarin piperazine (piperidine) derivatives as potential multireceptor atypical antipsychotics.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Biological Availability; Coumarins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; In Vitro Techniques; Isoxazoles; Lethal Dose 50; Mice; Motor Activity; Prolactin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Dopamine D3; Structure-Activity Relationship; Weight Gain | 2013 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Synthesis and biological evaluation of a series of aminoalkyl-tetralones and tetralols as dual dopamine/serotonin ligands.
Topics: Antipsychotic Agents; Dopamine; Dopamine D2 Receptor Antagonists; Humans; Ligands; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Tetralones | 2014 |
Synthesis and evaluation of new coumarin derivatives as potential atypical antipsychotics.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Coumarins; Magnetic Resonance Spectroscopy; Mice; Spectrometry, Mass, Electrospray Ionization | 2014 |
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides | 2014 |
Targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors for developing effective antipsychotics: synthesis, biological characterization, and behavioral studies.
Topics: Amides; Animals; Antipsychotic Agents; Behavior, Animal; Dizocilpine Maleate; Dopamine Antagonists; Drug Evaluation, Preclinical; Female; Kinetics; Ligands; Male; Mice; Prefrontal Cortex; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D3; Schizophrenia; Serotonin Receptor Agonists; Structure-Activity Relationship | 2014 |
Synthesis and pharmacological evaluation of piperidine (piperazine)-substituted benzoxazole derivatives as multi-target antipsychotics.
Topics: Animals; Antipsychotic Agents; Ether-A-Go-Go Potassium Channels; Humans; Mice; Oxazoles; Patch-Clamp Techniques; Piperazines; Piperidines; Potassium Channel Blockers; Rats; Receptors, Dopamine D2; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Structure-Activity Relationship; Swine | 2015 |
Synthesis and Biological Evaluation of Fused Tricyclic Heterocycle Piperazine (Piperidine) Derivatives As Potential Multireceptor Atypical Antipsychotics.
Topics: Animals; Antipsychotic Agents; Body Weight; Chemistry Techniques, Synthetic; Drug Design; Ether-A-Go-Go Potassium Channels; Heterocyclic Compounds; Memory; Mice; Piperazine; Rats; Schizophrenia; Structure-Activity Relationship; Tissue Distribution | 2018 |
Discovery of aryl-piperidine derivatives as potential antipsychotic agents using molecular hybridization strategy.
Topics: Animals; Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Structure; Piperidines; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Serotonin Antagonists; Structure-Activity Relationship | 2020 |
Cross-tapering clozapine and risperidone.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Monitoring; Female; Humans; Risperidone; Schizophrenia, Paranoid | 1995 |
Adverse reaction reporting and new antipsychotics.
Topics: Agranulocytosis; Anemia, Aplastic; Antipsychotic Agents; Clozapine; Drug Monitoring; Humans; Isoxazoles; Neutropenia; Piperidines; Remoxipride; Risperidone; Schizophrenia | 1993 |
Occupancy of central neurotransmitter receptors by risperidone, clozapine and haloperidol, measured ex vivo by quantitative autoradiography.
Topics: Animals; Antipsychotic Agents; Apomorphine; Autoradiography; Behavior, Animal; Clozapine; Guinea Pigs; Haloperidol; In Vitro Techniques; Iodine Radioisotopes; Isoxazoles; Male; Mescaline; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Neurotransmitter; Receptors, Serotonin; Risperidone; Stereotyped Behavior | 1993 |
Pharmacological action of zotepine and other antipsychotics on central 5-hydroxytryptamine receptor subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Behavior, Animal; Body Temperature; Clozapine; Dibenzothiepins; Exploratory Behavior; Haloperidol; Isoxazoles; Male; Mice; Motor Activity; Piperazines; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists | 1994 |
Serotonin2 receptor-mediated excitation of interneurons in piriform cortex: antagonism by atypical antipsychotic drugs.
Topics: Action Potentials; Animals; Antipsychotic Agents; Bicuculline; Cerebral Cortex; Chlorpromazine; Clozapine; Electrophysiology; gamma-Aminobutyric Acid; Haloperidol; In Vitro Techniques; Interneurons; Isoxazoles; Male; Membrane Potentials; Piperidines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin Antagonists | 1994 |
Dystonic reaction and relapse with clozapine discontinuation and risperidone intiation.
Topics: Adult; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Dystonia; Humans; Isoxazoles; Male; Neurologic Examination; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology; Substance Withdrawal Syndrome | 1994 |
Response to clozapine as a predictor of risperidone response in schizophrenia.
Topics: Adult; Antipsychotic Agents; Clozapine; Female; Humans; Isoxazoles; Piperidines; Receptors, Dopamine; Risperidone; Schizophrenia; Treatment Outcome | 1994 |
Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity.
Topics: Animals; Antipsychotic Agents; Brain; Clone Cells; Clozapine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Guinea Pigs; Haloperidol; Humans; Isoxazoles; Paliperidone Palmitate; Piperidines; Pyrimidines; Rats; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Serotonin Antagonists | 1994 |
Blockade of the discriminative stimulus effects of DOI by MDL 100,907 and the 'atypical' antipsychotics, clozapine and risperidone.
Topics: Amphetamines; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Fluorobenzenes; Isoxazoles; Male; Motor Activity; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Risperidone; Serotonin Antagonists | 1994 |
Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors.
Topics: Animals; Antipsychotic Agents; Autoradiography; Clozapine; Haloperidol; In Vitro Techniques; Isoxazoles; Male; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Neurotransmitter; Receptors, Serotonin; Risperidone | 1993 |
Effects of typical and atypical antipsychotic drugs on response decrement patterns in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Conditioning, Operant; Dose-Response Relationship, Drug; Haloperidol; Isoxazoles; Male; Piperidines; Rats; Rats, Wistar; Remoxipride; Risperidone; Serotonin Antagonists; Sulpiride | 1995 |
Novel neuroleptics in schizophrenia: theory and clinical relevance.
Topics: Antipsychotic Agents; Brain; Clozapine; Humans; Isoxazoles; Piperidines; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 1994 |
Addressing emerging social needs of patients treated with new neuroleptics.
Topics: Adult; Antipsychotic Agents; Clozapine; Female; Humans; Isoxazoles; Male; Middle Aged; Nursing Assessment; Piperidines; Psychiatric Nursing; Risperidone; Schizophrenia; Socialization | 1994 |
Recent developments in antipsychotic therapy. Introduction.
Topics: Antipsychotic Agents; Clozapine; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1995 |
Switching patients from clozapine to risperidone therapy.
Topics: Antipsychotic Agents; Clonazepam; Clozapine; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoxazoles; Lorazepam; Piperidines; Risperidone; Schizophrenia; Substance Withdrawal Syndrome | 1995 |
Effect of clozapine and risperidone on 5-HT2 and D2-dopamine receptor binding in the post-mortem human brain. An autoradiographic study.
Topics: Adult; Antipsychotic Agents; Autopsy; Autoradiography; Binding Sites; Brain; Clozapine; Humans; Isoxazoles; Male; Middle Aged; Piperidines; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone | 1995 |
Risperidone augmentation of clozapine.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Isoxazoles; Male; Piperidines; Psychotic Disorders; Risperidone; Schizophrenia, Paranoid; Schizophrenic Psychology | 1995 |
Clinical implications of clozapine discontinuation: report of an NIMH workshop.
Topics: Antipsychotic Agents; Clozapine; Drug Administration Schedule; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia; Schizophrenic Psychology; Substance Withdrawal Syndrome; United States; United States Food and Drug Administration | 1995 |
Unexpected dystonia while changing from clozapine to risperidone.
Topics: Adult; Antipsychotic Agents; Clozapine; Dystonia; Humans; Isoxazoles; Male; Piperidines; Risperidone; Schizophrenia | 1995 |
Is risperidone a substitute for clozapine for patients who do not respond to neuroleptics?
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Piperidines; Recurrence; Risperidone; Schizophrenia; Schizophrenia, Paranoid | 1995 |
Pharmacokinetic interaction between risperidone and clozapine.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Interactions; Drug Therapy, Combination; Humans; Isoxazoles; Male; Piperidines; Psychotic Disorders; Risperidone | 1995 |
Olanzapine, an atypical antipsychotic, increases rates of punished responding in pigeons.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzodiazepines; Chlordiazepoxide; Clozapine; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Haloperidol; Isoxazoles; Male; Olanzapine; Piperidines; Pirenzepine; Punishment; Risperidone | 1995 |
The costs of psychotropic medication.
Topics: Antipsychotic Agents; Budgets; Clozapine; Costs and Cost Analysis; Drug Monitoring; Humans; Mental Disorders; Psychotropic Drugs; Risperidone | 1995 |
The pharmacological profile of iloperidone, a novel atypical antipsychotic agent.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Basal Ganglia Diseases; Behavior, Animal; Clozapine; Dopamine Antagonists; Haloperidol; Isoxazoles; Male; Mice; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Risperidone; Saimiri; Serotonin Antagonists | 1995 |
Pharmaceuticals and politics.
Topics: Antipsychotic Agents; Clozapine; Drug Costs; Health Policy; Humans; Politics; Risperidone; Schizophrenia; United States | 1995 |
Risperidone guidelines.
Topics: Antipsychotic Agents; Clozapine; Guidelines as Topic; Humans; Mental Disorders; Patient Selection; Risperidone | 1995 |
Effects of atypical antipsychotic agents on social behavior in rodents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Catalepsy; Chlorpromazine; Clozapine; Diazepam; Haloperidol; Isoxazoles; Male; Mice; Mice, Inbred Strains; Piperidines; Raclopride; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Salicylamides; Social Behavior | 1993 |
[A study on the pharmacological properties of atypical antipsychotic drugs: in vivo dopamine and serotonin receptor occupancy by atypical antipsychotic drugs in the rat brain].
Topics: Animals; Antipsychotic Agents; Autoradiography; Brain; Chlorpromazine; Clozapine; Dibenzothiepins; Flupenthixol; Haloperidol; In Vitro Techniques; Isoxazoles; Male; Piperidines; Pyrimidinones; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Risperidone | 1993 |
Clozapine in the management of schizophrenia. Risperidone is less toxic but equally effective.
Topics: Antipsychotic Agents; Clozapine; Drug Costs; Humans; Isoxazoles; Piperidines; Risperidone; Schizophrenia | 1993 |
Biphasic displacement of [3H]YM-09151-2 binding in the rat brain by thioridazine, risperidone and clozapine, but not by other antipsychotics.
Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Clozapine; Corpus Striatum; Dopamine D2 Receptor Antagonists; In Vitro Techniques; Isoxazoles; Male; Olfactory Pathways; Piperidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Risperidone; Spiperone; Thioridazine | 1993 |
Pharmacological effects of zotepine and other antipsychotics on the central 5-HT2 receptors.
Topics: Animals; Antipsychotic Agents; Clozapine; Dibenzothiepins; Haloperidol; Isoxazoles; Male; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Risperidone | 1993 |
D4 dopamine receptor binding affinity does not distinguish between typical and atypical antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Clozapine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Spiperone | 1995 |
Risperidone versus clozapine in the treatment of psychosis in six patients with Parkinson's disease and other akinetic-rigid syndromes.
Topics: Aged; Antiparkinson Agents; Clozapine; Dyskinesia, Drug-Induced; Humans; Male; Parkinson Disease; Parkinson Disease, Secondary; Psychoses, Substance-Induced; Risperidone | 1995 |
Risperidone response after no clozapine response.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Clozapine; Humans; Male; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1995 |
Treatment of somatic delusional disorder with atypical antipsychotic agents.
Topics: Antipsychotic Agents; Clozapine; Delusions; Humans; Male; Middle Aged; Risperidone; Treatment Outcome | 1996 |
Agranulocytosis after addition of risperidone to clozapine treatment.
Topics: Adult; Agranulocytosis; Clozapine; Drug Therapy, Combination; Female; Humans; Psychotic Disorders; Risperidone | 1996 |
Cautions in the clozapine-to-risperidone switch.
Topics: Antipsychotic Agents; Cholinergic Fibers; Clozapine; Dopamine Antagonists; Humans; Risperidone; Serotonin Antagonists | 1995 |
[The affinities of mosapramine for the dopamine receptor subtypes in human cell lines expressing D2, D3 and D4 receptors].
Topics: Antipsychotic Agents; Benzazepines; Cell Line; Clozapine; Haloperidol; Humans; Raclopride; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Dopamine D5; Risperidone; Salicylamides; Spiperone | 1996 |
The moderate affinity of clozapine at H3 receptors is not shared by its two major metabolites and by structurally related and unrelated atypical neuroleptics.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Binding, Competitive; Clozapine; Dibenzothiepins; Dose-Response Relationship, Drug; Histamine Antagonists; Isotope Labeling; Male; Methylhistamines; Mice; Olanzapine; Pirenzepine; Rats; Rats, Wistar; Receptors, Histamine H3; Remoxipride; Risperidone; Structure-Activity Relationship; Thioridazine; Tritium | 1996 |
Clozapine withdrawal effects and receptor profiles of typical and atypical neuroleptics.
Topics: Antipsychotic Agents; Clozapine; Drug Administration Schedule; Humans; Male; Receptors, Dopamine; Receptors, GABA; Risperidone; Substance Withdrawal Syndrome | 1996 |
Positron emission tomography of in-vivo binding characteristics of atypical antipsychotic drugs. Review of D2 and 5-HT2 receptor occupancy studies and clinical response.
Topics: Antipsychotic Agents; Brain; Clozapine; Dose-Response Relationship, Drug; Humans; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed | 1996 |
Dystonia while changing from clozapine to risperidone.
Topics: Antipsychotic Agents; Clozapine; Drug Interactions; Dystonia; Humans; Risperidone | 1996 |
Cognitive dysfunction in schizophrenia: comparison of treatment with atypical antipsychotic agents and conventional neuroleptic drugs.
Topics: Clozapine; Cognition; Fluphenazine; Haloperidol; Humans; Maze Learning; Risperidone; Schizophrenia | 1996 |
Hoarding and clozapine-risperidone combination.
Topics: Adult; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Obsessive-Compulsive Disorder; Risperidone; Schizophrenia, Disorganized; Stereotyped Behavior | 1996 |
Each of the following statements about the newer medications for schizophrenia, risperidone (risperidol) and clozapine (clozaril), is true, except: Patients receiving risperidone are at risk for agranulocytosis.
Topics: Antipsychotic Agents; Clozapine; Humans; Risperidone; Schizophrenia | 1995 |
Chronic antipsychotic treatment alters glycine-stimulated NMDA receptor binding in rat brain.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Autoradiography; Binding, Competitive; Brain Chemistry; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glycine; Haloperidol; Male; Pimozide; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Risperidone; Time Factors; Tritium | 1996 |
[Behavioral assessment of neuroleptics (3)--Schizophrenia negative symptoms-like model induced by PCP].
Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clozapine; Desipramine; Disease Models, Animal; Humans; Immobilization; Mice; Phencyclidine; Risperidone; Schizophrenia; Swimming | 1996 |
Evaluation of perospirone (SM-9018), a novel serotonin-2 and dopamine-2 receptor antagonist, and other antipsychotics in the conditioned fear stress-induced freezing behavior model in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Dopamine Antagonists; Fear; Indoles; Isoindoles; Male; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin Antagonists; Thiazoles | 1996 |
Risperidone: regional effects in vivo on release and metabolism of dopamine and serotonin in the rat brain.
Topics: Animals; Antipsychotic Agents; Brain; Cerebral Cortex; Clozapine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Male; Microdialysis; Nucleus Accumbens; Raclopride; Rats; Rats, Wistar; Risperidone; Salicylamides; Serotonin; Time Factors | 1996 |
Differential effect of antipsychotics on place navigation of rats in the Morris water maze. A comparative study between novel and reference antipsychotics.
Topics: Animals; Antipsychotic Agents; Clozapine; Haloperidol; Male; Maze Learning; Rats; Rats, Wistar; Risperidone | 1996 |
Behavioral effects of sertindole, risperidone, clozapine and haloperidol in Cebus monkeys.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Cebus; Clozapine; Dose-Response Relationship, Drug; Haloperidol; Imidazoles; Indoles; Risperidone | 1996 |
Lymphocytopenia and thrombocytopenia during treatment with risperidone or clozapine.
Topics: Adult; Antipsychotic Agents; Clozapine; Humans; Lymphopenia; Male; Risperidone; Thrombocytopenia | 1996 |
Seroquel restores sensorimotor gating in phencyclidine-treated rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Dibenzothiazepines; Haloperidol; Male; Phencyclidine; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Reflex, Startle; Risperidone | 1996 |
Chronic treatment with typical and atypical antipsychotics increases the AMPA-preferring form of AMPA receptor in rat brain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Brain; Clozapine; Haloperidol; Male; Pimozide; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Risperidone; Tritium | 1996 |
Antipsychotics with inverse agonist activity at the dopamine D3 receptor.
Topics: Animals; Antipsychotic Agents; Calcium; CHO Cells; Clozapine; Colforsin; Cricetinae; Cyclic AMP; DNA Replication; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Flupenthixol; Glioma; Haloperidol; Humans; Hybrid Cells; Naphthalenes; Neuroblastoma; Pertussis Toxin; Phenothiazines; Pimozide; Pyrrolidines; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D3; Recombinant Proteins; Risperidone; Salicylamides; Second Messenger Systems; Sulpiride; Tetrahydronaphthalenes; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1996 |
[Compliance determines therapeutic success in schizophrenia. Strategy in initial therapy].
Topics: Chronic Disease; Clozapine; Humans; Patient Compliance; Risperidone; Schizophrenia | 1995 |
Negative symptoms or catatonia?
Topics: Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Benzodiazepinones; Child; Clobazam; Clozapine; Diagnosis, Differential; Drug Therapy, Combination; Electroconvulsive Therapy; Epilepsy, Generalized; Female; Humans; Risperidone; Schizophrenia, Catatonic; Schizophrenia, Childhood; Schizophrenic Psychology | 1997 |
Chronic schizophrenia: response to clozapine, risperidone, and paroxetine.
Topics: Chronic Disease; Clozapine; Drug Therapy, Combination; Humans; Middle Aged; Paroxetine; Risperidone; Schizophrenia | 1997 |
Effects of switching inpatients with treatment-resistant schizophrenia from clozapine to risperidone.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Chronic Disease; Clozapine; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neurologic Examination; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1996 |
Effects of risperidone, clozapine and haloperidol on extracellular recordings of substantia nigra reticulata neurons of the rat brain.
Topics: Animals; Antipsychotic Agents; Basal Ganglia; Clozapine; Dopamine Antagonists; Dose-Response Relationship, Drug; Electrophysiology; Haloperidol; Injections, Intravenous; Male; Neurons; Rats; Rats, Wistar; Receptors, Dopamine D2; Reticulocytes; Risperidone; Serotonin Antagonists; Substantia Nigra | 1997 |
Switching between clozapine and risperidone treatment.
Topics: Adult; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Psychotic Disorders; Risk Factors; Risperidone; Substance Withdrawal Syndrome | 1997 |
[Risperidone after clozapine in therapy refractory schizoaffective psychosis--a case report].
Topics: Adult; Amitriptyline; Antipsychotic Agents; Clozapine; Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Prognosis; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Treatment Outcome | 1997 |
Atypical antipsychotics block the excitatory effects of serotonin in septohippocampal neurons in the rat.
Topics: Animals; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Hippocampus; Male; Neurons; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin | 1997 |
BIMG 80, a novel potential antipsychotic drug: evidence for multireceptor actions and preferential release of dopamine in prefrontal cortex.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; CHO Cells; Clozapine; Corpus Striatum; COS Cells; Cricetinae; Dibenzothiazepines; Dopamine; Female; Guinea Pigs; Haloperidol; Indoles; Kidney; Male; Microdialysis; Neuroblastoma; Nucleus Accumbens; Olanzapine; Piperazines; Pirenzepine; Prefrontal Cortex; Pyridines; Quetiapine Fumarate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Risperidone; Tritium; Tumor Cells, Cultured | 1997 |
Effects of clozapine, thioridazine, risperidone and haloperidol on behavioral tests related to extrapyramidal motor function.
Topics: Animals; Antipsychotic Agents; Cholinesterase Inhibitors; Clozapine; Conditioning, Operant; Extrapyramidal Tracts; Haloperidol; Jaw; Male; Rats; Rats, Sprague-Dawley; Risperidone; Tacrine; Thioridazine | 1997 |
Conventional versus atypical neuroleptics: subjective quality of life in schizophrenic patients.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Cross-Sectional Studies; Depression; Dibenzothiepins; Female; Humans; Male; Middle Aged; Quality of Life; Risperidone; Schizophrenia; Schizophrenic Psychology | 1997 |
D2 dopamine receptor occupancy: a crossover comparison of risperidone with clozapine therapy in schizophrenic patients.
Topics: Adult; Benzamides; Clozapine; Humans; Iodine Radioisotopes; Male; Middle Aged; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia | 1997 |
Disruption of latent inhibition in the rat by the 5-HT2 agonist DOI: effects of MDL 100,907, clozapine, risperidone and haloperidol.
Topics: Amphetamines; Animals; Antipsychotic Agents; Clozapine; Conditioning, Operant; Fluorobenzenes; Haloperidol; Male; Piperidines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Reinforcement, Psychology; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists | 1997 |
A naturalistic pilot study comparing haloperidol, clozapine, sertindole, and risperidone in partially responsive chronic schizophrenia or schizoaffective disorder.
Topics: Adult; Antipsychotic Agents; Clozapine; Female; Haloperidol; Humans; Imidazoles; Indoles; Male; Psychotic Disorders; Risperidone; Schizophrenia; Treatment Failure | 1997 |
Risperidone inhibits 5-hydroxytryptaminergic neuronal activity in the dorsal raphe nucleus by local release of 5-hydroxytryptamine.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Clozapine; Dopamine Antagonists; Hydroxyindoleacetic Acid; Idazoxan; Male; Piperazines; Prazosin; Pyridines; Raclopride; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Serotonin; Risperidone; Salicylamides; Serotonin; Serotonin Antagonists | 1997 |
The effects of the atypical antipsychotics clozapine, remoxipride and risperidone on the contractile characteristics of rat skeletal muscle in vitro.
Topics: Animals; Antipsychotic Agents; Caffeine; Clozapine; Dantrolene; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Halothane; In Vitro Techniques; Muscle Contraction; Muscle Relaxants, Central; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Remoxipride; Risperidone; Trifluoperazine | 1997 |
The new antipsychotics, and their potential for early intervention in schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Disease Progression; Dopamine Antagonists; Humans; Risperidone; Schizophrenia; Serotonin Antagonists; Time Factors | 1997 |
Antipsychotic drug regulation of AMPA receptor affinity states and GluR1, GluR2 splice variant expression.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alternative Splicing; Animals; Antipsychotic Agents; Autoradiography; Binding, Competitive; Brain Chemistry; Clozapine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; Haloperidol; In Situ Hybridization; Male; Pimozide; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Risperidone; RNA, Messenger; Sodium Chloride; Tritium | 1998 |
Relation of serum anticholinergicity to cognitive status in schizophrenia patients taking clozapine or risperidone.
Topics: Adult; Cholinergic Antagonists; Clozapine; Cognition Disorders; Female; Humans; Male; Middle Aged; Muscarinic Antagonists; Psychiatric Status Rating Scales; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Cholinergic; Risperidone; Schizophrenia; Schizophrenic Psychology; Tritium | 1998 |
Sertindole and dopamine D2 receptor occupancy in comparison to risperidone, clozapine and haloperidol - a 123I-IBZM SPECT study.
Topics: Adult; Antipsychotic Agents; Benzamides; Clozapine; Female; Haloperidol; Humans; Imidazoles; Indoles; Iodine Radioisotopes; Male; Middle Aged; Neostriatum; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon | 1998 |
Atypical antipsychotic agents in the treatment of schizophrenia and other psychiatric disorders. Part I: Unique patient populations.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Humans; Mental Disorders; Middle Aged; Risperidone; Schizophrenia; Treatment Outcome; Violence | 1998 |
Iodine-123-iodobenzamide SPECT assessment of dopamine D2 receptor occupancy in riperidone-treated schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Brain; Clozapine; Contrast Media; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Iodine Radioisotopes; Male; Middle Aged; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon | 1998 |
Managing antipsychotic-induced acute and tardive dystonia.
Topics: Antipsychotic Agents; Cholinergic Antagonists; Clozapine; Dyskinesia, Drug-Induced; Dystonia; Humans; Prevalence; Risk Factors; Risperidone | 1998 |
The new antipsychotic compounds: is a clinical choice algorithm possible?
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone; Schizophrenia | 1998 |
Two new atypical antipsychotics: advantages and disadvantages.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Drug Interactions; Humans; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone; Schizophrenia | 1998 |
Choosing among old and new antipsychotics.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Humans; Psychotic Disorders; Receptors, Dopamine; Receptors, Neurotransmitter; Risk Factors; Risperidone; Schizophrenia | 1996 |
Some, but not all, antipsychotic drugs potentiate a low level of prepulse inhibition shown by rats of the Wistar strain.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Benzodiazepines; Clozapine; Haloperidol; Imidazoles; Indoles; Injections, Intraperitoneal; Male; Neural Inhibition; Olanzapine; Pirenzepine; Prazosin; Rats; Rats, Wistar; Reflex, Startle; Remoxipride; Risperidone; Ritanserin; Serotonin Antagonists | 1997 |
Antipsychotic drugs induce similar effects on the release of dopamine and noradrenaline in the medial prefrontal cortex of the rat brain.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Clozapine; Dopamine; Dopamine Agonists; Extracellular Space; Haloperidol; Male; Norepinephrine; Olanzapine; Piperazines; Pirenzepine; Prefrontal Cortex; Rats; Rats, Wistar; Reference Values; Risperidone; Tetrahydronaphthalenes; Thiazoles | 1998 |
Prolongation of QT interval in isolated feline hearts by antipsychotic drugs.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Cats; Clozapine; Electrocardiography; Haloperidol; Heart; Humans; Imidazoles; In Vitro Techniques; Indoles; Risperidone | 1998 |
5-HT2A receptor blockade in patients with schizophrenia treated with risperidone or clozapine. A SPET study using the novel 5-HT2A ligand 123I-5-I-R-91150.
Topics: Adult; Basal Ganglia Diseases; Clozapine; Female; Humans; Iodine Radioisotopes; Male; Piperidines; Receptors, Serotonin; Risperidone; Schizophrenia; Serotonin Antagonists; Tomography, Emission-Computed, Single-Photon | 1998 |
Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Carbon Radioisotopes; Clozapine; Drug Administration Schedule; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Pyrimidinones; Raclopride; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Salicylamides; Schizophrenia; Tomography, Emission-Computed | 1999 |
Novel antipsychotic medications in the treatment of children and adolescents.
Topics: Adolescent; Antipsychotic Agents; Benzodiazepines; Child; Child Psychiatry; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Pirenzepine; Practice Patterns, Physicians'; Quetiapine Fumarate; Risperidone; United States | 1999 |
Catatonia under medication with risperidone in a 61-year-old patient.
Topics: Antipsychotic Agents; Catatonia; Clozapine; Delusions; Dose-Response Relationship, Drug; Female; Humans; Middle Aged; Risperidone; Schizophrenia, Paranoid; Treatment Refusal | 1999 |
New antipsychotic drugs produce better outcomes.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Disease Management; Drug Costs; Humans; Mental Health Services; New York City; Olanzapine; Pirenzepine; Psychotic Disorders; Risperidone; Treatment Outcome | 1997 |
A cost-effectiveness clinical decision analysis model for schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cost-Benefit Analysis; Decision Support Systems, Clinical; Haloperidol; Humans; Markov Chains; Olanzapine; Pirenzepine; Quality-Adjusted Life Years; Risperidone; Schizophrenia; Treatment Outcome; United States | 1998 |
Cost-benefit analysis of risperidone and clozapine in the treatment of schizophrenia in Israel.
Topics: Antipsychotic Agents; Clozapine; Cost-Benefit Analysis; Humans; Israel; Risperidone; Schizophrenia | 1998 |
Looking beyond the formulary budget in cost-benefit analysis.
Topics: Antipsychotic Agents; Budgets; Clozapine; Cost of Illness; Cost-Benefit Analysis; Drug Costs; Formularies as Topic; Humans; Mental Health Services; Retrospective Studies; Risperidone; Saskatchewan; Schizophrenia; United States; Value of Life | 1997 |
Risperidone and clozapine combination for the treatment of refractory schizophrenia.
Topics: Adult; Clozapine; Drug Therapy, Combination; Humans; Male; Middle Aged; Risperidone; Schizophrenia | 1999 |
Effect of atypical antipsychotic drugs on 5-HT2 receptors in the rat orbito-frontal cortex: an in vivo electrophysiological study.
Topics: Amphetamines; Animals; Antipsychotic Agents; Bicuculline; Clozapine; Electrophysiology; GABA Antagonists; Iontophoresis; Male; Neurons; Piperazines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, GABA-A; Receptors, Serotonin; Risperidone; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |
Introduction: What makes an antipsychotic atypical?
Topics: Antipsychotic Agents; Clozapine; Humans; Loxapine; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Terminology as Topic | 1999 |
Rehospitalization rates of patients recently discharged on a regimen of risperidone or clozapine.
Topics: Adult; Antipsychotic Agents; Clozapine; Female; Hospitals, Psychiatric; Hospitals, State; Humans; Male; Patient Discharge; Patient Readmission; Psychotic Disorders; Recurrence; Risk Factors; Risperidone; Schizophrenia; Treatment Outcome | 1999 |
Weight gain and antipsychotic medications.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Obesity; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Weight Gain | 1999 |
Clozapine and other 5-hydroxytryptamine-2A receptor antagonists alter the subcellular distribution of 5-hydroxytryptamine-2A receptors in vitro and in vivo.
Topics: 3T3 Cells; Animals; Antipsychotic Agents; Benzodiazepines; Cell Line; Clozapine; Dendrites; Fluorobenzenes; Haloperidol; Mianserin; Mice; Olanzapine; Piperidines; Pirenzepine; Prefrontal Cortex; Pyramidal Cells; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Recombinant Proteins; Risperidone; Ritanserin; Serotonin Antagonists; Transfection | 1999 |
Risperidone and clozapine for treatment-resistant schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Drug Administration Schedule; Humans; Randomized Controlled Trials as Topic; Research Design; Risperidone; Schizophrenia; Treatment Outcome | 1999 |
Risperidone and clozapine for treatment-resistant schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Humans; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Treatment Outcome | 1999 |
Risperidone and clozapine for treatment-resistant schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Dibenzothiazepines; Humans; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Research Design; Risperidone; Schizophrenia; Treatment Outcome | 1999 |
Risperidone use at a state hospital: a clinical audit 2 years after the first wave of risperidone prescriptions.
Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; Bipolar Disorder; Clozapine; Dementia; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Hospitalization; Hospitals, Psychiatric; Hospitals, State; Humans; Length of Stay; Male; Mental Disorders; Patient Readmission; Psychotic Disorders; Retrospective Studies; Risperidone; Schizophrenia | 1999 |
Seizures after discontinuation of low-dose lorazepam from originally seizure-free clozapine regimen: combined effects?
Topics: Adult; Anti-Anxiety Agents; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electroencephalography; Humans; Lorazepam; Male; Risperidone; Schizophrenia; Seizures; Substance Withdrawal Syndrome | 1999 |
Stimulation of dopamine release in the bed nucleus of stria terminalis. A trait of atypical antipsychotics?
Topics: Amygdala; Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Dopamine; Haloperidol; Indoles; Male; Olanzapine; Pirenzepine; Pyridines; Raclopride; Rats; Rats, Sprague-Dawley; Risperidone; Salicylamides; Thalamus | 1999 |
Weight gain: side effect of atypical neuroleptics?
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Body Mass Index; Clozapine; Delusions; Dibenzothiepins; Female; Humans; Long-Term Care; Male; Middle Aged; Psychotic Disorders; Retrospective Studies; Risperidone; Schizophrenia; Sulpiride; Weight Gain | 1999 |
Antipsychotic polypharmacy, Part 1: Therapeutic option or dirty little secret?
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Drug Therapy, Combination; Humans; Olanzapine; Pirenzepine; Polypharmacy; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Schizophrenia | 1999 |
Clozapine versus risperidone in treatment-refractory schizophrenia: possible impact of dosing strategies.
Topics: Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1999 |
In vivo receptor occupancy of NRA0045, a putative atypical antipsychotic, in rats.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Cerebral Cortex; Clozapine; Corpus Striatum; Dopamine Antagonists; Haloperidol; Male; Nucleus Accumbens; Pyrrolidines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Schizophrenia; Thiazoles | 1999 |
Use patterns for antipsychotic medications in medicaid patients with schizophrenia.
Topics: Ambulatory Care; Antipsychotic Agents; California; Clozapine; Cohort Studies; Drug Costs; Drug Utilization; Episode of Care; Health Care Costs; Health Services Needs and Demand; Humans; Insurance Claim Reporting; Medicaid; Multivariate Analysis; Risperidone; Schizophrenia; United States | 1999 |
Relative weight gain among antipsychotics.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Obesity; Olanzapine; Pirenzepine; Risperidone; Weight Gain | 1999 |
Effects of atypical antipsychotic drugs vs. haloperidol on expression of heat shock protein in the discrete brain regions of phencyclidine-treated rats.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Clozapine; Corpus Striatum; Gene Expression Regulation; Gyrus Cinguli; Haloperidol; HSP70 Heat-Shock Proteins; Male; Nucleus Accumbens; Olanzapine; Phencyclidine; Pirenzepine; Prefrontal Cortex; Rats; Rats, Wistar; Risperidone; RNA, Messenger | 1999 |
Elevated serum triglycerides with clozapine resolved with risperidone in four patients.
Topics: Adult; Antipsychotic Agents; Clozapine; Humans; Male; Psychotic Disorders; Risk Factors; Risperidone; Triglycerides | 1999 |
Use of antipsychosis and adjunctive medications by an inner urban community psychiatric service.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Community Mental Health Services; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Utilization; Female; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Urban Population | 1999 |
The effects of typical antipsychotics, clozapine, and risperidone on neuropsychological test performance in schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Humans; Mental Recall; Paired-Associate Learning; Psychomotor Performance; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1999 |
Atypical antipsychotics and dopamine D(1) receptor agonism: an in vivo experimental study using core temperature measurements in the rat.
Topics: Animals; Antipsychotic Agents; Benzazepines; Benzodiazepines; Clozapine; Dibenzothiazepines; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Fever; Hypothermia; Male; Olanzapine; Pirenzepine; Quetiapine Fumarate; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Risperidone; Time Factors | 2000 |
Increase of dialysate dopamine in the bed nucleus of stria terminalis by clozapine and related neuroleptics.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Dopamine; Kinetics; Male; Microdialysis; Olanzapine; Piperazines; Pirenzepine; Rats; Rats, Sprague-Dawley; Risperidone; Septal Nuclei | 2000 |
Quinpirole, 8-OH-DPAT and ketanserin modulate catalepsy induced by high doses of atypical antipsychotics.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Benzodiazepines; Catalepsy; Clozapine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Imidazoles; Indoles; Ketanserin; Male; Mice; Mice, Inbred BALB C; Olanzapine; Pirenzepine; Quinpirole; Random Allocation; Rats; Rats, Wistar; Risperidone; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity | 1999 |
Comparison of clozapine and risperidone.
Topics: Analysis of Variance; Antipsychotic Agents; Chi-Square Distribution; Clinical Trials as Topic; Clozapine; Humans; Models, Statistical; Research Design; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2000 |
Discriminant cognitive factors in responder and non-responder patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Attention; Clozapine; Cognition Disorders; Dibenzothiazepines; Female; Humans; Male; Memory, Short-Term; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Quetiapine Fumarate; Retention, Psychology; Risperidone; Schizophrenia; Schizophrenic Language; Schizophrenic Psychology; Treatment Outcome; Verbal Behavior | 1999 |
The effect of serotonin(1A) receptor agonism on antipsychotic drug-induced dopamine release in rat striatum and nucleus accumbens.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Clozapine; Corpus Striatum; Dopamine; Fluorobenzenes; Haloperidol; Male; Microdialysis; Nucleus Accumbens; Piperazines; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Risperidone; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium | 2000 |
Effect of atypical antipsychotics on phencyclidine-induced expression of arc in rat brain.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Clozapine; Cytoskeletal Proteins; Gene Expression; Haloperidol; Male; Nerve Tissue Proteins; Olanzapine; Phencyclidine; Pirenzepine; Rats; Rats, Wistar; Risperidone; RNA, Messenger; Tissue Distribution | 2000 |
Effects of age, medication, and illness duration on the N-acetyl aspartate signal of the anterior cingulate region in schizophrenia.
Topics: Adult; Antipsychotic Agents; Aspartic Acid; Chronic Disease; Clozapine; Creatine; Female; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphocreatine; Reference Values; Risperidone; Schizophrenia; Treatment Outcome | 2000 |
Comparison of the effects of clozapine, risperidone, and olanzapine on ketamine-induced alterations in regional brain metabolism.
Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Brain; Brain Chemistry; Clozapine; Deoxyglucose; Excitatory Amino Acid Antagonists; Ketamine; Male; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Risperidone | 2000 |
Tardive dyskinesia in older patients.
Topics: Adult; Age Factors; Aged; Alzheimer Disease; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Drug Administration Schedule; Dyskinesia, Drug-Induced; Female; Humans; Incidence; Male; Middle Aged; Olanzapine; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Risk Factors; Risperidone | 2000 |
The discriminative stimulus properties of the atypical antipsychotic olanzapine in rats.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Discrimination Learning; Generalization, Psychological; Haloperidol; Male; Olanzapine; Pirenzepine; Raclopride; Rats; Rats, Sprague-Dawley; Risperidone; Ritanserin; Scopolamine | 2000 |
Rapid recovery of self-stimulation responding from depression by clozapine is prevented by the alpha 2-adrenoceptor agonist, clonidine.
Topics: Adrenergic alpha-Agonists; Animals; Antipsychotic Agents; Clonidine; Clozapine; Depression; Dose-Response Relationship, Drug; Electric Stimulation; Idazoxan; Male; Rats; Risperidone; Self Stimulation; Tegmentum Mesencephali | 1999 |
Clozapine and risperidone: combination/augmentation treatment of refractory schizophrenia: a preliminary observation.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Middle Aged; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index | 2000 |
Normal P50 suppression in schizophrenia patients treated with atypical antipsychotic medications.
Topics: Acoustic Stimulation; Adult; Antipsychotic Agents; Auditory Perception; Benzodiazepines; Clozapine; Cognition Disorders; Electroencephalography; Evoked Potentials, Auditory; Female; Humans; Male; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology | 2000 |
Clozapine discrimination with a low training dose distinguishes atypical from typical antipsychotic drugs in rats.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Discrimination Learning; Imidazoles; Indoles; Male; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Risperidone | 2000 |
Clozapine-like motor effects of the atypical antipsychotic risperidone in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Conditioning, Operant; Forelimb; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reaction Time; Risperidone | 2000 |
Side Effects of Antipsychotic Medications: Physician's Choice of Medication and Patient Compliance. Dallas, Texas, California. January 22, 1999. Proceedings of a roundtable.
Topics: Agranulocytosis; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Patient Compliance; Pirenzepine; Practice Patterns, Physicians'; Quality of Life; Quetiapine Fumarate; Risperidone | 2000 |
Side effects of antipsychotics in the elderly.
Topics: Age Factors; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Clinical Trials as Topic; Clozapine; Comorbidity; Dementia; Dibenzothiazepines; Humans; Movement Disorders; Neuroleptic Malignant Syndrome; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Schizophrenia | 2000 |
[Atypical antipsychotics].
Topics: Acute Disease; Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Cost-Benefit Analysis; Dibenzothiazepines; Dibenzothiepins; Dyskinesia, Drug-Induced; Germany; Humans; Neurotransmitter Agents; Olanzapine; Patient Compliance; Pirenzepine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Sulpiride | 2000 |
[Diminution of hand writing area and D2-dopamine receptor blockade. Results from treatment with typical and atypical neuroleptics].
Topics: Adult; Aged; Antipsychotic Agents; Benzamides; Clozapine; Dopamine Antagonists; Female; Haloperidol; Handwriting; Humans; Male; Middle Aged; Neostriatum; Pyrrolidines; Receptors, Dopamine; Risperidone; Schizophrenia, Paranoid; Therapeutic Equivalency; Tomography, Emission-Computed, Single-Photon | 2000 |
Adjunctive risperidone treatment in patients with 'clozapine-resistant schizophrenia'.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Resistance; Drug Therapy, Combination; Humans; Male; Risperidone; Schizophrenia | 2000 |
Antipsychotic drugs and risk of homicide.
Topics: Antipsychotic Agents; Clozapine; Delayed-Action Preparations; Homicide; Humans; Patient Compliance; Psychotic Disorders; Risperidone | 2000 |
Comparative efficacy of risperidone and clozapine in the treatment of patients with refractory schizophrenia or schizoaffective disorder: a retrospective analysis.
Topics: Adult; Aggression; Clozapine; Drug Administration Schedule; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Retrospective Studies; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2000 |
Advantages of depot antipsychotics.
Topics: Antipsychotic Agents; Clozapine; Delayed-Action Preparations; Homicide; Humans; Patient Compliance; Psychotic Disorders; Risperidone | 2000 |
Atrial ectopics with clozapine-risperidone combination.
Topics: Adult; Cardiotonic Agents; Clozapine; Female; Humans; Risperidone; Serotonin Antagonists; Tachycardia, Ectopic Atrial | 1997 |
Risperidone in treatment of choreoathetosis of Huntington's disease.
Topics: Clozapine; Dopamine Antagonists; Female; Humans; Huntington Disease; Middle Aged; Risperidone; Serotonin Antagonists | 1997 |
Olanzapine appears haematologically safe in patients who developed blood dyscrasia on clozapine and risperidone.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Clozapine; Drug Monitoring; Humans; Leukopenia; Male; Neutropenia; Olanzapine; Pirenzepine; Risk Factors; Risperidone; Schizophrenia, Paranoid | 2000 |
Combined 5-HT2/D2 receptor blockade inhibits the firing rate of SNR neurons in the rat brain.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Electrophysiology; Male; Neurons; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Substantia Nigra | 2000 |
Severe self-injurious behavior associated with treatment-resistant schizophrenia: treatment with maintenance electroconvulsive therapy.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Resistance; Electroconvulsive Therapy; Haloperidol; Humans; Male; Risperidone; Schizophrenia; Schizophrenic Psychology; Self-Injurious Behavior | 2000 |
The effect of the antipsychotic drug mosapramine on the expression of Fos protein in the rat brain: comparison with haloperidol, clozapine and risperidone.
Topics: Animals; Antipsychotic Agents; Benzazepines; Brain; Clozapine; Corpus Striatum; Gene Expression Regulation; Genes, fos; Haloperidol; Immunohistochemistry; Male; Neurons; Nucleus Accumbens; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Risperidone | 2000 |
The 5-HT2 antagonist ritanserin blocks dopamine re-uptake in the rat frontal cortex.
Topics: Animals; Clozapine; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Frontal Lobe; Haloperidol; Ketanserin; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Risperidone; Ritanserin; Serotonin Antagonists; Synaptosomes; Tritium | 2000 |
Dopamine and 5-HT turnover are increased by the mGlu2/3 receptor agonist LY379268 in rat medial prefrontal cortex, nucleus accumbens and striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Clozapine; Corpus Striatum; Dopamine; Excitatory Amino Acid Agonists; Homovanillic Acid; Hydroxyindoleacetic Acid; Kinetics; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Risperidone; Serotonin | 2000 |
Clozapine therapy for a patient with a history of Hodgkin's disease.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Clozapine; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Leukopenia; Remission Induction; Risperidone; Treatment Outcome; Valproic Acid | 2001 |
Addition of risperidone to clozapine therapy in chronically psychotic inpatients.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Clozapine; Drug Therapy, Combination; Female; Hospitalization; Humans; Male; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2001 |
Health care utilization in patients with schizophrenia maintained on atypical versus conventional antipsychotics.
Topics: Administration, Oral; Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Clozapine; Delayed-Action Preparations; Emergency Service, Hospital; Female; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Office Visits; Ontario; Patient Care; Patient Compliance; Retrospective Studies; Risperidone; Schizophrenia; Schizophrenic Psychology | 2001 |
Frequency of sexual dysfunctions in patients with schizophrenia on haloperidol, clozapine or risperidone.
Topics: Antipsychotic Agents; Clozapine; Female; Haloperidol; Humans; Male; Risperidone; Schizophrenia; Sexual Dysfunction, Physiological | 2001 |
Acute increases in monoamine release in the rat prefrontal cortex by the mGlu2/3 agonist LY379268 are similar in profile to risperidone, not locally mediated, and can be elicited in the presence of uptake blockade.
Topics: Amino Acids; Animals; Biogenic Monoamines; Bridged Bicyclo Compounds, Heterocyclic; Clozapine; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Agonists; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Risperidone; Serotonin; Serotonin Antagonists | 2001 |
In vitro modulation of the firing rate of dopamine neurons in the rat substantia nigra pars compacta and the ventral tegmental area by antipsychotic drugs.
Topics: Action Potentials; Animals; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Male; Neurons; Rats; Rats, Wistar; Receptors, Dopamine D2; Risperidone; Substantia Nigra; Sulpiride; Ventral Tegmental Area | 2001 |
Re-awakenings? A discourse analysis of the recovery from schizophrenia after medication change.
Topics: Adaptation, Psychological; Antipsychotic Agents; Attitude to Health; Clozapine; Female; Humans; Internal-External Control; Male; Nursing Methodology Research; Recovery of Function; Risperidone; Schizophrenia; Schizophrenic Psychology; Self Care; Self Concept; Surveys and Questionnaires; Time Factors; Treatment Outcome | 2001 |
The effect of institutional fiscal stress on the use of atypical antipsychotic medications in the treatment of schizophrenia.
Topics: Alzheimer Disease; Antipsychotic Agents; Benzodiazepines; Budgets; Clozapine; Comorbidity; Depressive Disorder; Drug Costs; Female; Health Care Costs; Health Facilities; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Practice Patterns, Physicians'; Regression Analysis; Risperidone; Schizophrenia; Treatment Outcome; United States; United States Department of Veterans Affairs | 2001 |
Brief report: effects of clozapine on self-injurious behavior of two risperidone nonresponders with mental retardation.
Topics: Adult; Clozapine; Dose-Response Relationship, Drug; Humans; Intellectual Disability; Male; Middle Aged; Risperidone; Self-Injurious Behavior; Single-Blind Method; Treatment Failure; Treatment Outcome | 2001 |
Ziprasidone: a novel antipsychotic agent with a unique human receptor binding profile.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Binding Sites; Binding, Competitive; Cell Line; Clozapine; Dibenzothiazepines; Dopamine Antagonists; Haloperidol; Humans; Neurons; Norepinephrine; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Rats; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Risperidone; Serotonin; Serotonin Antagonists; Thiazoles | 2001 |
Chronic treatment with certain antipsychotic drugs preserves upregulation of regulator of G-protein signalling 2 mRNA in rat striatum as opposed to c-fos mRNA.
Topics: Animals; Antipsychotic Agents; Clozapine; Drug Administration Schedule; GTP-Binding Proteins; Haloperidol; In Situ Hybridization; Male; Neostriatum; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; RGS Proteins; Risperidone; RNA, Messenger; Signal Transduction; Up-Regulation | 2001 |
Atypical neuroleptic drugs downregulate dopamine sensitivity in rat cortical and striatal astrocytes.
Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Antipsychotic Agents; Astrocytes; Benzodiazepines; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Clozapine; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Down-Regulation; Haloperidol; Intracellular Fluid; Neostriatum; Olanzapine; Pirenzepine; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D4; Risperidone; Serotonin Antagonists; Sulpiride | 2001 |
Clozapine-risperidone combination in treatment-resistant schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Clozapine; Drug Resistance; Drug Therapy, Combination; Humans; Male; Risperidone; Schizophrenia | 2001 |
The DBA/2J strain and prepulse inhibition of startle: a model system to test antipsychotics?
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Benzylidene Compounds; Bridged-Ring Compounds; Clozapine; Male; Mice; Mice, Inbred DBA; Models, Psychological; Nicotinic Agonists; Pyridines; Receptors, Nicotinic; Reflex, Startle; Risperidone; Spiro Compounds | 2001 |
Long-term evaluation of isolation-rearing induced prepulse inhibition deficits in rats.
Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Conditioning, Psychological; Handling, Psychological; Male; Models, Psychological; Motor Activity; Olanzapine; Pirenzepine; Rats; Reflex, Startle; Risperidone; Social Isolation; Socialization | 2001 |
Evaluation of dopamine D-2 receptor occupancy by clozapine, risperidone, and haloperidol in vivo in the rodent and nonhuman primate brain using 18F-fallypride.
Topics: Animals; Antipsychotic Agents; Autoradiography; Benzamides; Brain; Clozapine; Dopamine Antagonists; Dose-Response Relationship, Drug; Fluorine Radioisotopes; Haloperidol; Macaca mulatta; Male; Neostriatum; Pyrrolidines; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Risperidone; Tomography, Emission-Computed | 2001 |
Risperidone added to clozapine: impact on serum prolactin levels.
Topics: Adult; Age of Onset; Ambulatory Care; Antipsychotic Agents; Chronic Disease; Clozapine; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hyperprolactinemia; Male; Middle Aged; Prolactin; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology | 2001 |
Agranulocytosis and neutropenia with typical and atypical neuroleptics.
Topics: Adult; Agranulocytosis; Antipsychotic Agents; Benzodiazepines; Clozapine; Female; Humans; Leukocyte Count; Neutropenia; Olanzapine; Perphenazine; Pirenzepine; Risperidone; Schizophrenia | 2001 |
Weight gain and antipsychotic medication: differences between antipsychotic-free and treatment periods.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Clozapine; Drug Administration Schedule; Female; Hospitalization; Humans; Male; Obesity; Olanzapine; Pirenzepine; Psychotic Disorders; Regression Analysis; Research Design; Retrospective Studies; Risperidone; Schizophrenia; Weight Gain | 2001 |
Potent antagonism of 5-HT(3) and 5-HT(6) receptors by olanzapine.
Topics: Animals; Benzodiazepines; Binding, Competitive; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Haloperidol; HeLa Cells; Humans; Ileum; In Vitro Techniques; Indoles; Lysergic Acid; Muscle Contraction; Olanzapine; Ondansetron; Pirenzepine; Quetiapine Fumarate; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfur Radioisotopes; Tritium; Tropisetron | 2001 |
A behavioural pattern analysis of hypoglutamatergic mice--effects of four different antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Dizocilpine Maleate; Dopamine Antagonists; Drug Combinations; Excitatory Amino Acid Antagonists; Fluorobenzenes; Glutamic Acid; Haloperidol; Injections, Intraperitoneal; Male; Mice; Motor Activity; Piperidines; Risperidone; Serotonin Antagonists | 2001 |
Inhibition of glucose transport in PC12 cells by the atypical antipsychotic drugs risperidone and clozapine, and structural analogs of clozapine.
Topics: Animals; Antimetabolites; Antipsychotic Agents; Biological Transport; Clozapine; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Hyperglycemia; Neurons; PC12 Cells; Rats; Risperidone; Structure-Activity Relationship; Tritium | 2001 |
Elevation of prolactin levels by atypical antipsychotics.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Prolactin; Risperidone; Schizophrenia | 2002 |
Concomitant clozapine reduces smoking in patients treated with risperidone.
Topics: Adult; Antipsychotic Agents; Clozapine; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pilot Projects; Risperidone; Schizophrenia; Smoking | 2002 |
No effect of reboxetine on plasma concentrations of clozapine, risperidone, and their active metabolites.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Clozapine; Drug Interactions; Female; Humans; Male; Middle Aged; Morpholines; Reboxetine; Risperidone | 2001 |
Service use and costs of treating schizophrenia with atypical antipsychotics.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clozapine; Cost-Benefit Analysis; Dose-Response Relationship, Drug; England; Female; Humans; Long-Term Care; Male; Middle Aged; Olanzapine; Patient Readmission; Pirenzepine; Psychiatric Status Rating Scales; Risperidone; Schizophrenia | 2001 |
Toxic interaction between risperidone and clozapine: a case report.
Topics: Adult; Antipsychotic Agents; Clozapine; Diagnosis, Differential; Drug Interactions; Humans; Male; Neuroleptic Malignant Syndrome; Neurotoxicity Syndromes; Risperidone; Schizophrenia | 2002 |
Short report: comparison of patient satisfaction and burden of adverse effects with novel and conventional neuroleptics: a naturalistic study.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Depressive Disorder, Major; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Neurologic Examination; Olanzapine; Patient Satisfaction; Pirenzepine; Risperidone; Schizophrenia; Schizophrenic Psychology | 2001 |
Atypical, but not typical, antipsychotic drugs increase cortical acetylcholine release without an effect in the nucleus accumbens or striatum.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Antipsychotic Agents; Benzodiazepines; Cerebral Cortex; Cholinesterase Inhibitors; Clozapine; Corpus Striatum; Haloperidol; Male; Nucleus Accumbens; Olanzapine; Oxotremorine; Piperazines; Pirenzepine; Rats; Rats, Sprague-Dawley; Risperidone; Scopolamine; Sulpiride; Thiazoles; Thioridazine | 2002 |
Effects of antipsychotic drugs on operant responding after acute and repeated administration.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Conditioning, Operant; Dibenzothiazepines; Dose-Response Relationship, Drug; Haloperidol; Imidazoles; Indoles; Male; Olanzapine; Pirenzepine; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Remoxipride; Risperidone; Thioridazine; Time Factors | 2002 |
Biochemical evidence that the atypical antipsychotic drugs clozapine and risperidone block 5-HT(2C) receptors in vivo.
Topics: Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; Clozapine; Dopamine; Electrochemistry; Extracellular Space; Haloperidol; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Risperidone; Serotonin Antagonists | 2002 |
Association of diabetes mellitus with use of atypical neuroleptics in the treatment of schizophrenia.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Antipsychotic Agents; Benzodiazepines; Clozapine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dibenzothiazepines; Female; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Quetiapine Fumarate; Regression Analysis; Risk Factors; Risperidone; Schizophrenia | 2002 |
Racial disparities in antipsychotic prescription patterns for patients with schizophrenia.
Topics: Adolescent; Adult; Antipsychotic Agents; Black or African American; Clozapine; Cross-Cultural Comparison; Delayed-Action Preparations; Drug Prescriptions; Drug Utilization; Female; Humans; Male; Medicaid; Middle Aged; Prejudice; Risperidone; Schizophrenia; United States; White People | 2002 |
Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine efflux in the hippocampus of the rat.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Dialysis Solutions; Dopamine Antagonists; Extracellular Space; Haloperidol; Hippocampus; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Microdialysis; Olanzapine; Piperazines; Pirenzepine; Rats; Rats, Wistar; Risperidone; Serotonin Antagonists; Thiazoles; Thioridazine | 2002 |
Sub-chronic treatment with classical but not atypical antipsychotics produces morphological changes in rat nigro-striatal dopaminergic neurons directly related to "early onset" vacuous chewing.
Topics: Amisulpride; Animals; Antipsychotic Agents; Clozapine; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Dyskinesia, Drug-Induced; Haloperidol; Male; Mastication; Neostriatum; Nerve Degeneration; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Risperidone; Substance Withdrawal Syndrome; Substantia Nigra; Sulpiride | 2002 |
Effects of atypical antipsychotics on vertebrate neuromuscular transmission.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Fluphenazine; In Vitro Techniques; Membrane Potentials; Motor Endplate; Neuromuscular Junction; Olanzapine; Pirenzepine; Rana pipiens; Rana temporaria; Risperidone; Sulpiride; Synaptic Transmission | 2002 |
Evaluation of the neurotoxic activity of typical and atypical neuroleptics: relevance to iatrogenic extrapyramidal symptoms.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Brain; Cell Cycle; Cell Survival; Clozapine; DNA Fragmentation; Dopamine; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Iatrogenic Disease; Mice; Mice, Inbred ICR; Neurons; Neurotoxins; Perphenazine; Pregnancy; Risperidone; Tumor Cells, Cultured | 2001 |
Antipsychotic prescribing practices in the Veterans Healthcare Administration--New York metropolitan region.
Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization; Hospitals, Veterans; Humans; Male; Middle Aged; New York City; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone; Schizophrenia; Urban Population; Veterans | 2002 |
Antipsychotic profile of 5-[2-[4-(6-fluoro-1H-indole-3-yl)piperidin-1-yl]ethyl]-4-(4-fluorophenyl)thiazole-2-carboxylic acid amide (NRA0562) in rats.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Clozapine; Dose-Response Relationship, Drug; Haloperidol; Male; Piperidines; Rats; Rats, Wistar; Risperidone; Thiazoles | 2002 |
Sexual side effects of novel antipsychotic medications.
Topics: Adult; Antipsychotic Agents; Clozapine; Erectile Dysfunction; Fluphenazine; Haloperidol; Humans; Male; Middle Aged; Prospective Studies; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Sexual Behavior | 2002 |
Extreme weight gain in a youth with schizophrenia: risk/benefit considerations.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Clozapine; Follow-Up Studies; Humans; Male; Obesity; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Weight Gain | 2002 |
Galantamine for treatment-resistant schizophrenia.
Topics: Adult; Agranulocytosis; Antipsychotic Agents; Cholinesterase Inhibitors; Clozapine; Drug Therapy, Combination; Galantamine; Humans; Male; Middle Aged; Parasympathomimetics; Risperidone; Schizophrenia | 2002 |
Striatal volume changes in the rat following long-term administration of typical and atypical antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Caudate Nucleus; Clozapine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Haloperidol; Hypertrophy; Male; Neostriatum; Neuronal Plasticity; Neurons; Putamen; Rats; Rats, Sprague-Dawley; Risperidone; Schizophrenia; Time Factors | 2002 |
Effects of risperidone on the peripheral noradrenegic system in patients with schizophrenia: a comparison with clozapine and placebo.
Topics: Adult; Clozapine; Dopamine Antagonists; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Neural Inhibition; Norepinephrine; Peripheral Nervous System; Placebos; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Risperidone; Schizophrenia; Serotonin Antagonists; Sympathetic Fibers, Postganglionic; Synaptic Transmission; Vasodilation | 2002 |
Neuroleptic malignant syndrome due to atypical neuroleptics: three episodes in one patient.
Topics: Amisulpride; Antipsychotic Agents; Clozapine; Female; Humans; Middle Aged; Neuroleptic Malignant Syndrome; Risperidone; Schizophrenia; Sulpiride | 2002 |
Protective effects of atypical antipsychotic drugs on PC12 cells after serum withdrawal.
Topics: Animals; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Blotting, Northern; Cell Culture Techniques; Cell Survival; Clozapine; Dibenzothiazepines; PC12 Cells; Quetiapine Fumarate; Rats; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Risperidone; RNA, Messenger; Superoxide Dismutase; Superoxide Dismutase-1 | 2002 |
In vitro and in vivo pharmacological profile of 5-[2-[4-(6-fluoro-1H-indole-3-yl)piperidin-1-yl]ethyl]-4-(4-fluorophenyl)thiazole-2-carboxylic acid amide (NRA0562), a novel and putative atypical antipsychotic.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Catalepsy; Central Nervous System Stimulants; Clozapine; Humans; Male; Methamphetamine; Motor Activity; Piperidines; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Receptors, Dopamine; Receptors, Drug; Receptors, Serotonin; Risperidone; Stereotyped Behavior; Thiazoles | 2002 |
Antipsychotic medication, prolactin elevation, and ovarian function in women with schizophrenia and schizoaffective disorder.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Estradiol; Female; Humans; Hyperprolactinemia; Menstrual Cycle; Menstruation Disturbances; Olanzapine; Pirenzepine; Progesterone; Prolactin; Prospective Studies; Risperidone; Schizophrenia | 2002 |
The value of atypical antipsychotics in the treatment of schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dopamine Antagonists; Drug Labeling; Humans; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Risperidone; Safety; Schizophrenia; Thiazoles; United States | 2002 |
Nicotine interactions with haloperidol, clozapine and risperidone and working memory function in rats.
Topics: Animals; Antipsychotic Agents; Brain; Clozapine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Female; Haloperidol; Maze Learning; Memory, Short-Term; Neural Pathways; Nicotine; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Dopamine; Risperidone; Schizophrenia | 2002 |
Differential regulation of hippocampal BDNF mRNA by typical and atypical antipsychotic administration.
Topics: Animals; Antipsychotic Agents; Blotting, Northern; Brain-Derived Neurotrophic Factor; Clozapine; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation; Haloperidol; Hippocampus; In Situ Hybridization; Male; Rats; Rats, Wistar; Remoxipride; Risperidone; Ritanserin; RNA, Messenger; Time Factors | 2002 |
The effects of novel antipsychotics on glucose and lipid levels.
Topics: Antipsychotic Agents; Benzodiazepines; Blood Glucose; Body Mass Index; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clozapine; Diabetes Mellitus, Type 2; Dibenzothiazepines; Female; Haloperidol; Humans; Hyperlipidemias; Lipids; Male; Middle Aged; Olanzapine; Pirenzepine; Psychotic Disorders; Quetiapine Fumarate; Retrospective Studies; Risk Factors; Risperidone; Triglycerides; Weight Gain | 2002 |
Differential effects of risperidone, olanzapine, clozapine, and conventional antipsychotics on type 2 diabetes: findings from a large health plan database.
Topics: Acute Disease; Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Comorbidity; Confidence Intervals; Databases as Topic; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Insurance Claim Review; Logistic Models; Male; Middle Aged; Odds Ratio; Olanzapine; Pirenzepine; Psychotic Disorders; Risk Factors; Risperidone; United States | 2002 |
Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: cohort study using administrative data.
Topics: Adult; Aged; Antipsychotic Agents; Arrhythmias, Cardiac; Clozapine; Cohort Studies; Confidence Intervals; Death, Sudden, Cardiac; Female; Haloperidol; Heart Arrest; Humans; Male; Medicaid; Middle Aged; Risperidone; Schizophrenia; Thioridazine; United States | 2002 |
Glucose intolerance with atypical antipsychotics.
Topics: Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Chlorpromazine; Clozapine; Diabetes Mellitus; Glucose Intolerance; Haloperidol; Humans; Hyperglycemia; Olanzapine; Pirenzepine; Risk Factors; Risperidone; World Health Organization | 2002 |
Patient characteristics and prescription patterns of atypical antipsychotics among patients with schizophrenia.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Drug Utilization; Female; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Practice Patterns, Physicians'; Quetiapine Fumarate; Registries; Risperidone; Schizophrenia; Sex Distribution; Socioeconomic Factors; United States; United States Department of Veterans Affairs | 2002 |
Olanzapine and clozapine increase the GABAergic neuroactive steroid allopregnanolone in rodents.
Topics: Adrenalectomy; Animals; Antipsychotic Agents; Benzodiazepines; Cerebral Cortex; Clozapine; Corticosterone; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Haloperidol; Male; Olanzapine; Pirenzepine; Pregnanolone; Progesterone; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Risperidone | 2003 |
Discriminative stimulus properties in rats of the novel antipsychotic quetiapine.
Topics: Amisulpride; Analysis of Variance; Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Dibenzothiazepines; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Generalization, Psychological; Haloperidol; Loxapine; Quetiapine Fumarate; Quinoxalines; Rats; Rats, Wistar; Risperidone; Sulpiride | 2002 |
A case of neuroleptic malignant syndrome with clozapine and risperidone.
Topics: Adult; Antipsychotic Agents; Clozapine; Humans; Male; Neuroleptic Malignant Syndrome; Risperidone; Schizophrenia, Paranoid | 2002 |
Combined use of atypical antipsychotics and cognitive-behavioural therapy in schizophrenia.
Topics: Adult; Antipsychotic Agents; Clozapine; Cognitive Behavioral Therapy; Combined Modality Therapy; Humans; Male; Risperidone; Schizophrenia | 2002 |
Insight in persons with schizophrenia: effects of switching from conventional neuroleptics to atypical antipsychotics.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition; Cognition Disorders; Female; Haloperidol; Humans; Male; Olanzapine; Patient Compliance; Pirenzepine; Risperidone; Schizophrenia; Severity of Illness Index; Treatment Outcome | 2002 |
Alcohol and cannabis use in schizophrenia: effects of clozapine vs. risperidone.
Topics: Adult; Aged; Alcohols; Antipsychotic Agents; Cannabis; Clozapine; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Retrospective Studies; Risperidone; Schizophrenia; Substance-Related Disorders; Treatment Outcome | 2003 |
Prescribing second-generation antipsychotics and the evolving standard of care in Italy.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Benzodiazepines; Brief Psychiatric Rating Scale; Clozapine; Community Mental Health Services; Dibenzothiazepines; Drug Therapy, Combination; Drug Utilization; Female; Humans; Italy; Male; Middle Aged; Olanzapine; Outpatients; Pharmacoepidemiology; Pirenzepine; Psychiatric Status Rating Scales; Quetiapine Fumarate; Risperidone; Schizophrenia; Treatment Outcome | 2002 |
Differential effects of haloperidol, risperidone, and clozapine exposure on cholinergic markers and spatial learning performance in rats.
Topics: Animals; Brain; Choline O-Acetyltransferase; Cholinergic Fibers; Clozapine; Haloperidol; Male; Maze Learning; Rats; Rats, Wistar; Risperidone; Spatial Behavior | 2003 |
alpha2C-Adrenoceptor blockade by clozapine and other antipsychotic drugs.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brimonidine Tartrate; Chlorpromazine; CHO Cells; Clozapine; Cricetinae; Cyclic AMP; Dibenzothiazepines; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Gene Expression; Haloperidol; Humans; Isoxazoles; Norepinephrine; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Quinolones; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Risperidone; Thiazoles; Transfection; Yohimbine | 2003 |
Acute effects of antipsychotic drugs on cardiovascular responses to stress.
Topics: Animals; Antipsychotic Agents; Blood Pressure; Clozapine; Dose-Response Relationship, Drug; Exploratory Behavior; Haloperidol; Heart Rate; Male; Motor Activity; Rats; Rats, Inbred F344; Risperidone; Stress, Psychological | 2003 |
Comparative effectiveness of antipsychotic drugs.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Haloperidol; Humans; Olanzapine; Pirenzepine; Psychotic Disorders; Research Design; Risperidone; Schizophrenia; Treatment Outcome | 2003 |
Comparative effectiveness of antipsychotic drugs.
Topics: Antipsychotic Agents; Chronic Disease; Clozapine; Cohort Effect; Cohort Studies; Haloperidol; Humans; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Research Design; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2003 |
Comparative effectiveness of antipsychotic drugs.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Haloperidol; Humans; Olanzapine; Pirenzepine; Randomized Controlled Trials as Topic; Reproducibility of Results; Research Design; Risperidone; Schizophrenia; Treatment Outcome | 2003 |
Comparative effectiveness of antipsychotic drugs.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Haloperidol; Humans; Olanzapine; Pirenzepine; Research Design; Research Support as Topic; Risperidone; Schizophrenia; Treatment Outcome | 2003 |
Comparison of the effects of antipsychotics on a delayed radial maze task in the rat.
Topics: Administration, Oral; Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition; Dose-Response Relationship, Drug; Food Deprivation; Haloperidol; Male; Maze Learning; Memory; Olanzapine; Piperazines; Pirenzepine; Rats; Rats, Sprague-Dawley; Risperidone; Thiazoles | 2003 |
Serum leptin and triglyceride levels in patients on treatment with atypical antipsychotics.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Clozapine; Dibenzothiazepines; Female; Follow-Up Studies; Glucose Tolerance Test; Humans; Leptin; Male; Obesity; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Quetiapine Fumarate; Risperidone; Schizophrenia; Treatment Outcome; Triglycerides; Weight Gain | 2003 |
Role changes experienced by clinical staff in relation to clients' recovery from psychosis.
Topics: Adult; Anecdotes as Topic; Antipsychotic Agents; Attitude of Health Personnel; Clozapine; Female; Humans; Male; Middle Aged; Nurse-Patient Relations; Nurse's Role; Nursing Methodology Research; Physician-Patient Relations; Physician's Role; Psychiatric Nursing; Psychotic Disorders; Risperidone; Time Factors; United States | 2003 |
Use of atypical antipsychotic drugs in patients with dementia.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Clozapine; Comorbidity; Dementia; Dibenzothiazepines; Humans; Mental Disorders; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone | 2003 |
Rehospitalization risk with second-generation and depot antipsychotics.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Data Collection; Delayed-Action Preparations; Female; Fluphenazine; Haloperidol; Humans; Male; Olanzapine; Patient Readmission; Pirenzepine; Risperidone; Schizophrenia; Secondary Prevention; Time Factors; Treatment Outcome | 2003 |
The atypical antipsychotics risperidone, clozapine and olanzapine differ regarding their sedative potency in rats.
Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Benzodiazepines; Clozapine; Conscious Sedation; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Combinations; Electroencephalography; Fourier Analysis; Hypnotics and Sedatives; Male; Olanzapine; Pirenzepine; Rats; Rats, Wistar; Risperidone; Stereotyped Behavior; Time Factors | 2003 |
Lack of a pharmacokinetic interaction between mirtazapine and the newer antipsychotics clozapine, risperidone and olanzapine in patients with chronic schizophrenia.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clinical Trials as Topic; Clozapine; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Italy; Male; Mianserin; Middle Aged; Mirtazapine; Olanzapine; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Time Factors | 2003 |
Basal-corticofrontal circuits in schizophrenia and obsessive-compulsive disorder: a controlled, double dissociation study.
Topics: Adult; Antipsychotic Agents; Basal Ganglia; Case-Control Studies; Clozapine; Corpus Striatum; Dissociative Disorders; Female; Frontal Lobe; Haloperidol; Humans; Male; Neural Pathways; Neuropsychological Tests; Obsessive-Compulsive Disorder; Predictive Value of Tests; Prefrontal Cortex; Risperidone; Schizophrenia | 2003 |
[Neuroleptics and cognition].
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition Disorders; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Middle Aged; Neuropsychological Tests; Olanzapine; Pirenzepine; Product Surveillance, Postmarketing; Risperidone; Schizophrenia; Schizophrenic Psychology | 2003 |
Schizophrenia, VI: Treatments.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Perphenazine; Piperazines; Pirenzepine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Thiazoles; Treatment Outcome | 2003 |
Racial disparity in the use of atypical antipsychotic medications among veterans.
Topics: Antipsychotic Agents; Benzodiazepines; Black or African American; Clozapine; Dibenzothiazepines; Drug Prescriptions; Ethnicity; Hispanic or Latino; Humans; Multivariate Analysis; Olanzapine; Pirenzepine; Quetiapine Fumarate; Risperidone; Schizophrenia; United States; Veterans; White People | 2003 |
Six-month review of weight and metabolic parameters in patients receiving clozapine, risperidone, olanzapine, or quetiapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Clozapine; Dibenzothiazepines; Drug Therapy, Combination; Female; Humans; Long-Term Care; Male; Middle Aged; Olanzapine; Pirenzepine; Quetiapine Fumarate; Retrospective Studies; Risk; Risperidone; Schizophrenia; Triglycerides; Weight Gain | 2003 |
Similarities and differences among antipsychotics.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Dibenzothiazepines; Haloperidol; Humans; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Thiazoles | 2003 |
Role of dopamine D3 receptor (DRD3) and dopamine transporter (DAT) polymorphism in cognitive dysfunctions and therapeutic response to atypical antipsychotics in patients with schizophrenia.
Topics: Adult; Alleles; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition Disorders; Dibenzothiazepines; Dopamine Plasma Membrane Transport Proteins; Female; Gene Frequency; Genotype; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Minisatellite Repeats; Nerve Tissue Proteins; Olanzapine; Polymorphism, Genetic; Quetiapine Fumarate; Receptors, Dopamine D2; Receptors, Dopamine D3; Risperidone; Schizophrenia | 2004 |
Nicotine-antipsychotic drug interactions and attentional performance in female rats.
Topics: Animals; Antipsychotic Agents; Attention; Central Nervous System Stimulants; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Female; Haloperidol; Nicotine; Photic Stimulation; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Risperidone | 2004 |
Simultaneous determination of clozapine, olanzapine, risperidone and quetiapine in plasma by high-performance liquid chromatography-electrospray ionization mass spectrometry.
Topics: Antipsychotic Agents; Benzodiazepines; Calibration; Chromatography, High Pressure Liquid; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Quetiapine Fumarate; Reference Standards; Risperidone; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2004 |
Antipsychotics increase microtubule-associated protein 2 mRNA but not spinophilin mRNA in rat hippocampus and cortex.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Cerebral Cortex; Chlorpromazine; Clozapine; Gene Expression Regulation; Haloperidol; Hippocampus; In Situ Hybridization; Male; Microfilament Proteins; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurites; Olanzapine; Rats; Rats, Sprague-Dawley; Risperidone; RNA, Messenger; Tissue Distribution | 2004 |
Comparison of risperidone and olanzapine as used under "real-world" conditions in a state psychiatric hospital.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Drug Therapy, Combination; Female; Hospitals, Psychiatric; Hospitals, State; Humans; Length of Stay; Male; Olanzapine; Psychiatric Status Rating Scales; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Treatment Outcome | 2004 |
COMT158 polymorphism and hostility.
Topics: Antipsychotic Agents; Benzodiazepines; Catechol O-Methyltransferase; Clozapine; Genotype; Haloperidol; Hostility; Humans; Methionine; Olanzapine; Polymorphism, Genetic; Risperidone; Schizophrenia; Schizophrenic Psychology; Valine | 2004 |
A comparison of incidence of diabetes mellitus between atypical antipsychotic drugs: a survey for clozapine, risperidone, olanzapine, and quetiapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Diabetes Mellitus; Dibenzothiazepines; Female; Humans; Incidence; Male; Middle Aged; Olanzapine; Quetiapine Fumarate; Retrospective Studies; Risperidone | 2004 |
Neuroleptic malignant syndrome and atypical antipsychotic drugs.
Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bromocriptine; Clozapine; Dantrolene; Dibenzothiazepines; Dopamine Agonists; Female; Humans; Intubation; Male; MEDLINE; Mental Disorders; Middle Aged; Muscle Relaxants, Central; Neuroleptic Malignant Syndrome; Olanzapine; Quetiapine Fumarate; Respiration, Artificial; Risperidone; Treatment Outcome | 2004 |
Inverse agonist properties of atypical antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Butaclamol; CHO Cells; Clozapine; Colforsin; Cricetinae; Cyclic AMP; Drug Interactions; Female; Humans; Receptors, Dopamine D2; Risperidone; Sodium | 2004 |
Chronic low dose risperidone and clozapine alleviate positive but not negative symptoms in the rat neonatal ventral hippocampal lesion model of schizophrenia.
Topics: Acoustic Stimulation; Animals; Animals, Newborn; Antipsychotic Agents; Behavior, Animal; Clozapine; Dose-Response Relationship, Drug; Female; Hippocampus; Male; Motor Activity; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Reflex, Startle; Risperidone; Schizophrenic Psychology; Social Behavior | 2004 |
Rate of new-onset diabetes among patients treated with atypical or conventional antipsychotic medications for schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Diabetes Mellitus; Dibenzothiazepines; Female; Humans; Incidence; Male; Managed Care Programs; Olanzapine; Patient Selection; Quetiapine Fumarate; Retrospective Studies; Risperidone; Schizophrenia | 2004 |
Effects of typical and atypical antipsychotic drugs on maternal behavior in postpartum female rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Dibenzothiazepines; Female; Haloperidol; Maternal Behavior; Postpartum Period; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Risperidone | 2004 |
Prolactin levels in antipsychotic treatment of patients with schizophrenia carrying the DRD2*A1 allele.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Clozapine; Dopamine Antagonists; Female; Genotype; Humans; Hyperprolactinemia; Male; Middle Aged; Olanzapine; Prolactin; Receptors, Dopamine D2; Risperidone; Schizophrenia; Sex Factors | 2004 |
Equivalent occupancy of dopamine D1 and D2 receptors with clozapine: differentiation from other atypical antipsychotics.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzazepines; Benzodiazepines; Carbon Radioisotopes; Clozapine; Corpus Striatum; Dibenzothiazepines; Female; Humans; Male; Middle Aged; Olanzapine; Prolactin; Psychotic Disorders; Quetiapine Fumarate; Raclopride; Receptors, Dopamine D1; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed; Treatment Outcome | 2004 |
Incidence of newly diagnosed diabetes attributable to atypical antipsychotic medications.
Topics: Ambulatory Care; Antipsychotic Agents; Benzodiazepines; Clozapine; Diabetes Mellitus; Diabetic Ketoacidosis; Dibenzothiazepines; Hospitalization; Humans; Incidence; Olanzapine; Proportional Hazards Models; Quetiapine Fumarate; Risk Factors; Risperidone; Schizophrenia; United States | 2004 |
Relationship between antipsychotic medication treatment and new cases of diabetes among psychiatric inpatients.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Case-Control Studies; Clozapine; Demography; Diabetes Mellitus; Dibenzothiazepines; Female; Humans; Hypoglycemic Agents; Male; Olanzapine; Quetiapine Fumarate; Risperidone; Schizophrenia; Sex Factors | 2004 |
Atypical antipsychotic drugs and diabetes mellitus in a large outpatient population: a retrospective cohort study.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Clozapine; Cohort Studies; Databases, Factual; Diabetes Mellitus; Dibenzothiazepines; Drug Prescriptions; Female; Humans; Incidence; Insurance Claim Reporting; Male; Middle Aged; Multivariate Analysis; Olanzapine; Outpatients; Piperazines; Quetiapine Fumarate; Retrospective Studies; Risperidone; Sex Factors; Thiazoles; Thioridazine; Time Factors; United States | 2005 |
Effects of typical and atypical antipsychotics on human glycine transporters.
Topics: Amino Acid Transport Systems, Neutral; Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chloride Channels; Choriocarcinoma; Clozapine; Female; Glycine; Glycine Plasma Membrane Transport Proteins; Haloperidol; Humans; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Olanzapine; Rats; Receptors, N-Methyl-D-Aspartate; Risperidone; Schizophrenia; Sodium Channels; Synapses; Uterine Neoplasms | 2004 |
Varied effects of atypical neuroleptics on P50 auditory gating in schizophrenia patients.
Topics: Acoustic Stimulation; Adult; Antipsychotic Agents; Auditory Perception; Benzodiazepines; Clozapine; Conditioning, Psychological; Dibenzothiazepines; Evoked Potentials, Auditory; Female; Humans; Male; Olanzapine; Psychiatric Status Rating Scales; Quetiapine Fumarate; Reaction Time; Reflex, Startle; Risperidone; Schizophrenia | 2004 |
Selective prescribing of atypical antipsychotics.
Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Cholinergic Antagonists; Clozapine; Delayed-Action Preparations; Disease Susceptibility; Drug Administration Schedule; Drug Monitoring; Drug Utilization Review; Female; Humans; Male; Medical Records, Problem-Oriented; Middle Aged; Netherlands; Olanzapine; Patient Selection; Pharmacoepidemiology; Risperidone; Treatment Outcome | 2005 |
[Intoxications with atypical antipsychotic drugs--data of the Acute Intoxication Unit in Wrocław].
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Female; Humans; Male; Middle Aged; Olanzapine; Poland; Psychotic Disorders; Risperidone | 2004 |
[Effect of clozapine and risperidone on serum cytokine levels in patients with first-episode paranoid schizophrenia].
Topics: Adolescent; Adult; Antipsychotic Agents; Clozapine; Cytokines; Female; Humans; Interleukin-18; Interleukin-2; Interleukin-6; Male; Risperidone; Schizophrenia, Paranoid; Tumor Necrosis Factor-alpha | 2004 |
Glucose metabolism in patients with schizophrenia treated with atypical antipsychotic agents: a frequently sampled intravenous glucose tolerance test and minimal model analysis.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Body Mass Index; Body Weight; Clozapine; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Humans; Insulin Resistance; Male; Metabolic Syndrome; Obesity; Olanzapine; Risperidone; Schizophrenia | 2005 |
The use of atypical antipsychotics in the treatment of schizophrenia in North Staffordshire.
Topics: Adult; Age Factors; Antipsychotic Agents; Benzodiazepines; Clozapine; Female; Humans; Male; Olanzapine; Retrospective Studies; Risperidone; Schizophrenia; Sex Factors; Survival Analysis; Time Factors; Treatment Outcome; United Kingdom | 2005 |
The impact of neuroleptic medication on seizure threshold and duration in electroconvulsive therapy.
Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Brain; Clopenthixol; Clozapine; Dibenzothiazepines; Electric Impedance; Electroconvulsive Therapy; Electroencephalography; Electromyography; Female; Fluphenazine; Haloperidol; Humans; Male; Middle Aged; Olanzapine; Quetiapine Fumarate; Risperidone; Seizures; Sulpiride | 2004 |
Olanzapine vs. other antipsychotics in actual out-patient settings: six months tolerability results from the European Schizophrenia Out-patient Health Outcomes study.
Topics: Adult; Ambulatory Care; Amenorrhea; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Clozapine; Dibenzothiazepines; Drug Tolerance; Female; Galactorrhea; Gynecomastia; Humans; Male; Observation; Olanzapine; Outcome Assessment, Health Care; Quetiapine Fumarate; Risperidone; Schizophrenia | 2005 |
Comparison of clozapine use in Maryland and in Victoria, Australia.
Topics: Adult; Ambulatory Care; Antipsychotic Agents; Australia; Benzodiazepines; Catchment Area, Health; Clozapine; Cross-Sectional Studies; Dibenzothiazepines; Drug Administration Schedule; Drug Prescriptions; Drug Utilization; Female; Humans; Male; Maryland; Medical Records; Olanzapine; Quetiapine Fumarate; Risperidone; Schizophrenia | 2005 |
Antipsychotic exposure and type 2 diabetes among patients with schizophrenia: a matched case-control study of California Medicaid claims.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; California; Case-Control Studies; Clozapine; Databases, Factual; Diabetes Mellitus, Type 2; Dibenzothiazepines; Drug Therapy, Combination; Female; Humans; Incidence; Logistic Models; Male; Medicaid; Middle Aged; Odds Ratio; Olanzapine; Quetiapine Fumarate; Risk Assessment; Risperidone; Schizophrenia; Time Factors | 2005 |
The effect of zotepine, risperidone, clozapine and olanzapine on MK-801-disrupted sensorimotor gating.
Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiepins; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Olanzapine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Muscarinic; Reflex, Startle; Risperidone | 2005 |
FDA warns antipsychotic drugs may be risky for elderly.
Topics: Aged; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Dementia; Dibenzothiazepines; Drug Approval; Drug Labeling; Humans; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Thiazoles; United States; United States Food and Drug Administration | 2005 |
Incidence of new-onset diabetes mellitus among patients receiving atypical neuroleptics in the treatment of mental illness: evidence from a privately insured population.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Diabetes Mellitus; Dibenzothiazepines; Female; Follow-Up Studies; Humans; Incidence; Insurance Coverage; Male; Mental Disorders; Olanzapine; Proportional Hazards Models; Quetiapine Fumarate; Risk Factors; Risperidone; Sex Factors; United States | 2005 |
Differences in prolactin elevation and related symptoms of atypical antipsychotics in schizophrenic patients.
Topics: Adult; Ambulatory Care; Antipsychotic Agents; Benzodiazepines; Clozapine; Cross-Sectional Studies; Female; Humans; Hyperprolactinemia; Male; Middle Aged; Olanzapine; Prevalence; Prolactin; Risperidone; Schizophrenia; Treatment Outcome | 2005 |
Atypical antipsychotics produce within-session decrements on self-stimulation of the rat medial prefrontal cortex.
Topics: Animals; Antipsychotic Agents; Clozapine; Haloperidol; Male; Prefrontal Cortex; Rats; Rats, Wistar; Risperidone; Self Stimulation | 2005 |
Pharmacokinetic-pharmacodynamic analysis of antipsychotics-induced extrapyramidal symptoms based on receptor occupancy theory incorporating endogenous dopamine release.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clozapine; Controlled Clinical Trials as Topic; Dibenzothiazepines; Haloperidol; Humans; Olanzapine; Piperazines; Quetiapine Fumarate; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Risperidone; Schizophrenia; Thiazoles | 2005 |
Neurologic soft signs in schizophrenic patients treated with conventional and atypical antipsychotics.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Haloperidol; Humans; Male; Nervous System Diseases; Neuropsychological Tests; Olanzapine; Risperidone; Schizophrenia; Severity of Illness Index | 2005 |
[Obsessive-compulsive symptoms treatment in: schizophrenia].
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Obsessive-Compulsive Disorder; Olanzapine; Risperidone; Schizophrenia; Severity of Illness Index | 2005 |
The effects of antipsychotics on beta-catenin, glycogen synthase kinase-3 and dishevelled in the ventral midbrain of rats.
Topics: Adaptor Proteins, Signal Transducing; Amphetamine; Animals; Antipsychotic Agents; Benzazepines; beta Catenin; Blotting, Western; Central Nervous System Stimulants; Clozapine; Cytoskeletal Proteins; Dishevelled Proteins; Dopamine Agonists; Female; Glycogen Synthase Kinase 3; Haloperidol; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Male; Mesencephalon; Phosphoproteins; Quinpirole; Rats; Rats, Sprague-Dawley; Risperidone; Signal Transduction; Trans-Activators; Wnt Proteins; Wnt1 Protein | 2005 |
Increase in gray matter and decrease in white matter volumes in the cortex during treatment with atypical neuroleptics in schizophrenia.
Topics: Adult; Antipsychotic Agents; Atrophy; Brain; Chronic Disease; Clozapine; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Risperidone; Schizophrenia | 2005 |
Atypical anti-psychotics in the real world--a naturalistic comparative outcome study.
Topics: Adolescent; Adult; Aged; Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Olanzapine; Patient Compliance; Probability; Prospective Studies; Psychiatric Status Rating Scales; Psychotic Disorders; Quality of Life; Quetiapine Fumarate; Risk Assessment; Risperidone; Severity of Illness Index; Statistics, Nonparametric; Sulpiride; Treatment Outcome | 2005 |
[Prescription of psychotropic drugs for schizophrenic outpatients in Hungary].
Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Clozapine; Cross-Sectional Studies; Drug Prescriptions; Female; Flupenthixol; Humans; Hungary; Male; Middle Aged; Olanzapine; Outpatients; Risperidone; Schizophrenia; Serotonin Antagonists; Surveys and Questionnaires | 2005 |
Clozapine, diabetes mellitus, hyperlipidemia, and cardiovascular risks and mortality: results of a 10-year naturalistic study.
Topics: Adult; Antipsychotic Agents; Black or African American; Cardiovascular Diseases; Cause of Death; Clozapine; Comorbidity; Diabetes Mellitus; Female; Hispanic or Latino; Humans; Hyperlipidemias; Longitudinal Studies; Male; Metabolic Syndrome; Psychotic Disorders; Risk Factors; Risperidone; Schizophrenia; Survival Analysis | 2005 |
Management of atypical antipsychotic-induced weight gain in schizophrenic patients with topiramate.
Topics: Adult; Anti-Obesity Agents; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Body Weight; Child, Preschool; Clozapine; Dibenzothiazepines; Female; Fructose; Humans; Male; Olanzapine; Psychiatric Status Rating Scales; Quetiapine Fumarate; Risperidone; Schizophrenia; Taiwan; Topiramate; Weight Gain | 2005 |
Nicotine and clozapine selectively reverse a PCP-induced deficit of PPI in BALB/cByJ but not NMRI mice: comparison with risperidone.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Female; Hallucinogens; Mice; Mice, Inbred BALB C; Neural Inhibition; Nicotine; Nicotinic Agonists; Phencyclidine; Reflex, Startle; Risperidone; Species Specificity | 2006 |
Weight gain as a prognostic indicator of therapeutic improvement during acute treatment of schizophrenia with placebo or active antipsychotic.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Double-Blind Method; Female; Haloperidol; Humans; Linear Models; Male; Meta-Analysis as Topic; Middle Aged; Olanzapine; Placebo Effect; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Schizophrenic Psychology; Time Factors; Treatment Outcome; Weight Gain | 2005 |
Antioxidant enzymes and lipid peroxidation in different forms of schizophrenia treated with typical and atypical antipsychotics.
Topics: Adult; Antipsychotic Agents; Catalase; Clozapine; Female; Free Radicals; Glutathione Peroxidase; Humans; Lipid Peroxidation; Male; Malondialdehyde; Middle Aged; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Superoxide Dismutase | 2006 |
Chronic nicotine interactions with clozapine and risperidone and attentional function in rats.
Topics: Animals; Antipsychotic Agents; Attention; Behavior, Animal; Clozapine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Reaction Time; Risperidone; Sensory Thresholds; Signal Detection, Psychological | 2006 |
[Utilization study of clozapine, olanzapine and risperidone in Hungary].
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Drug Prescriptions; Humans; Hungary; Olanzapine; Retrospective Studies; Risperidone | 2004 |
Neuroleptic malignant syndrome associated with risperidone in a male with early-onset schizophrenia.
Topics: Administration, Oral; Adolescent; Antipsychotic Agents; Clozapine; Combined Modality Therapy; Electroconvulsive Therapy; Humans; Injections, Intramuscular; Male; Methotrimeprazine; Neuroleptic Malignant Syndrome; Recurrence; Risperidone; Schizophrenia | 2005 |
Overdoses and ingestions of second-generation antipsychotics in children and adolescents.
Topics: Adolescent; Antipsychotic Agents; Cause of Death; Child; Clozapine; Drug Overdose; Female; Humans; Male; Neurologic Examination; Risperidone; Survival Rate | 2005 |
Homocysteine levels and glucose metabolism in non-obese, non-diabetic chronic schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Blood Pressure; Chronic Disease; Clozapine; Community Mental Health Centers; Female; Folic Acid; Homeostasis; Homocysteine; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Nutrition Assessment; Olanzapine; Prediabetic State; Psychotic Disorders; Reference Values; Risk Factors; Risperidone; Schizophrenia; Sex Factors; Statistics as Topic; Waist-Hip Ratio | 2006 |
Increased risk of extrapyramidal side-effect treatment associated with atypical antipsychotic polytherapy.
Topics: Adolescent; Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clozapine; Cross-Sectional Studies; Delayed-Action Preparations; Dibenzothiazepines; Drug Therapy, Combination; Female; Humans; Iowa; Male; Mathematical Computing; Medicaid; Middle Aged; Models, Statistical; Olanzapine; Product Surveillance, Postmarketing; Psychotic Disorders; Quetiapine Fumarate; Regression Analysis; Risk Factors; Risperidone; Statistics as Topic | 2006 |
The choice of drugs for schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Humans; Risperidone; Schizophrenia | 2006 |
[Possible connection between ghrelin, resistin and TNF-alpha levels and the metabolic syndrome caused by atypical antipsychotics].
Topics: Antipsychotic Agents; Benzodiazepines; Carbohydrate Metabolism; Case-Control Studies; Clozapine; Dibenzothiazepines; Female; Ghrelin; Humans; Insulin Resistance; Male; Metabolic Syndrome; Middle Aged; Obesity; Olanzapine; Overweight; Peptide Hormones; Quetiapine Fumarate; Resistin; Risperidone; Tumor Necrosis Factor-alpha; Weight Gain | 2005 |
Haloperidol and atypical antipsychotics share a same action of decreasing P75(NTR) mRNA levels in PC12 cells.
Topics: Animals; Antipsychotic Agents; Cell Survival; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression; Haloperidol; PC12 Cells; Quetiapine Fumarate; Rats; Receptor, Nerve Growth Factor; Risperidone; RNA, Messenger; Time Factors | 2006 |
Long-term antipsychotic treatments and crossover studies in rats: differential effects of typical and atypical agents on the expression of antioxidant enzymes and membrane lipid peroxidation in rat brain.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chlorpromazine; Clozapine; Cross-Over Studies; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Haloperidol; Lipid Peroxidation; Male; Membrane Lipids; Olanzapine; Rats; Rats, Wistar; Risperidone; Schizophrenia; Superoxide Dismutase | 2007 |
Prototypical antipsychotic drugs protect hippocampal neuronal cultures against cell death induced by growth medium deprivation.
Topics: Animals; Anisoles; Antipsychotic Agents; Benzazepines; Butaclamol; Caspase Inhibitors; Cell Death; Cells, Cultured; Chlorpromazine; Clozapine; Domperidone; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Ginkgo biloba; Haloperidol; Hippocampus; Indans; Isoxazoles; Neurons; Neuroprotective Agents; Peptides; Piperidines; Plant Extracts; Propylamines; Raclopride; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Remoxipride; Risperidone; Sulpiride | 2006 |
Practical treatment information for schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Dibenzothiazepines; Female; Humans; Male; Multicenter Studies as Topic; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Treatment Outcome | 2006 |
[Therapy with antipsychotic drugs as a risk factor for diabetes in schizophrenia: a case-control study].
Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Case-Control Studies; Clozapine; Diabetes Mellitus; Female; Humans; Hyperglycemia; Hyperlipidemias; Male; Middle Aged; Olanzapine; Risk Factors; Risperidone; Schizophrenia | 2006 |
Clozapine alone versus clozapine and risperidone for refractory schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Confidence Intervals; Drug Therapy, Combination; Humans; Risperidone; Schizophrenia | 2006 |
Clozapine alone versus clozapine and risperidone for refractory schizophrenia.
Topics: Antipsychotic Agents; Bias; Clozapine; Drug Therapy, Combination; Humans; Risperidone; Schizophrenia | 2006 |
Regulation of mouse brain glycogen synthase kinase-3 by atypical antipsychotics.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Brain; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Male; Mice; Mice, Inbred C57BL; Olanzapine; Phosphorylation; Piperazines; Quetiapine Fumarate; Risperidone; Selective Serotonin Reuptake Inhibitors; Serine; Thiazoles; Time Factors | 2007 |
Inhibition of the glycine transporter GlyT-1 potentiates the effect of risperidone, but not clozapine, on glutamatergic transmission in the rat medial prefrontal cortex.
Topics: Animals; Biological Transport, Active; Clozapine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Male; Organ Culture Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Risperidone; Sarcosine; Synaptic Transmission | 2006 |
Atypical antipsychotics and pituitary tumors: a pharmacovigilance study.
Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Amenorrhea; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Child; Clozapine; Dibenzothiazepines; Female; Galactorrhea; Gynecomastia; Haloperidol; Humans; Hyperprolactinemia; Male; Olanzapine; Piperazines; Pituitary Neoplasms; Quetiapine Fumarate; Quinolones; Retrospective Studies; Risperidone; Sex Factors; Thiazoles; United States; United States Food and Drug Administration | 2006 |
Positive modulation of glutamatergic receptors potentiates the suppressive effects of antipsychotics on conditioned avoidance responding in rats.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; Clozapine; Conditioning, Psychological; Dioxoles; Drug Synergism; Isoxazoles; Male; Olanzapine; Paliperidone Palmitate; Piperidines; Pyrimidines; Rats; Rats, Wistar; Receptors, AMPA; Risperidone; Serine; Stereoisomerism | 2006 |
Comparison between risperidone, olanzapine, and clozapine in the management of chronic schizophrenia: a naturalistic prospective 12-week observational study.
Topics: Adolescent; Adult; Aged; Aggression; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Body Weight; Cholesterol; Chronic Disease; Clozapine; Creatine Kinase; Female; Humans; Male; Middle Aged; Olanzapine; Prospective Studies; Risperidone; Schizophrenia; Sex Factors; Triglycerides | 2006 |
Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein.
Topics: Animals; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzodiazepines; Chlorpromazine; Clozapine; Cyclosporins; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Flow Cytometry; Fluorescent Dyes; Haloperidol; Isoxazoles; Kidney; Liver; LLC-PK1 Cells; Olanzapine; Paliperidone Palmitate; Pyrimidines; Quetiapine Fumarate; Rhodamine 123; Risperidone; Swine; Transfection | 2006 |
Atypical antipsychotic use for adult outpatients in New Zealand's Auckland and Northland regions.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization Review; Female; Humans; Male; Mental Disorders; Middle Aged; New Zealand; Olanzapine; Practice Patterns, Physicians'; Quetiapine Fumarate; Retrospective Studies; Risperidone | 2006 |
Comparison of time to rehospitalization among schizophrenic patients discharged on typical antipsychotics, clozapine or risperidone.
Topics: Adult; Age of Onset; Antipsychotic Agents; Clozapine; Female; Humans; Male; Middle Aged; Patient Compliance; Patient Readmission; Risperidone; Schizophrenia; Time Factors | 2006 |
A model of anticholinergic activity of atypical antipsychotic medications.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Binding Sites; Clozapine; Cognition Disorders; Dibenzothiazepines; Dose-Response Relationship, Drug; Female; Humans; Male; Neuropsychological Tests; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Receptors, Cholinergic; Risperidone; Schizophrenia; Thiazoles | 2006 |
Chronic high-dose haloperidol has qualitatively similar effects to risperidone and clozapine on immediate-early gene and tyrosine hydroxylase expression in the rat locus coeruleus but not medial prefrontal cortex.
Topics: Animals; Antipsychotic Agents; Cell Count; Clozapine; Gene Expression; Genes, Immediate-Early; Haloperidol; Immediate-Early Proteins; Immunohistochemistry; Locus Coeruleus; Male; Neurons; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Risperidone; Tyrosine 3-Monooxygenase | 2007 |
Psychometric characteristics of role-play assessments of social skill in schizophrenia.
Topics: Adult; Antipsychotic Agents; Clozapine; Comorbidity; Crime Victims; Diabetes Mellitus, Type 2; Female; Health Behavior; Humans; Problem Solving; Psychometrics; Risperidone; Role Playing; Schizophrenia; Social Behavior; Social Perception; Substance-Related Disorders | 2006 |
Serum BDNF levels and weight gain in schizophrenic patients on long-term treatment with antipsychotics.
Topics: Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Chronic Disease; Clozapine; Female; Humans; Male; Middle Aged; Risperidone; Schizophrenia; Serum; Weight Gain | 2007 |
Weight gain associated with clozapine, olanzapine and risperidone in children and adolescents.
Topics: Adolescent; Antipsychotic Agents; Benzodiazepines; Body Weight; Child; Clozapine; Female; Humans; Male; Mental Disorders; Olanzapine; Risperidone; Weight Gain | 2007 |
Remission and relapse in the outpatient care of schizophrenia: three-year results from the Schizophrenia Outpatient Health Outcomes study.
Topics: Adult; Ambulatory Care; Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Cohort Studies; Dibenzothiazepines; Europe; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Olanzapine; Prospective Studies; Quetiapine Fumarate; Recurrence; Risk Factors; Risperidone; Schizophrenia; Sulpiride; Time Factors; Treatment Outcome | 2006 |
Propranolol blocks chronic risperidone treatment-induced enhancement of spatial working memory performance of rats in a delayed matching-to-place water maze task.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Male; Maze Learning; Memory; Propranolol; Rats; Rats, Sprague-Dawley; Risperidone; Schizophrenia; Space Perception | 2007 |
Abnormalities in the fatty acid composition of the postmortem orbitofrontal cortex of schizophrenic patients: gender differences and partial normalization with antipsychotic medications.
Topics: Adult; Aged; Antipsychotic Agents; Arachidonic Acid; Benzodiazepines; Brain; Clozapine; Diagnostic and Statistical Manual of Mental Disorders; Docosahexaenoic Acids; Fatty Acid Desaturases; Fatty Acids; Fatty Acids, Omega-3; Female; Humans; Male; Middle Aged; Olanzapine; Prefrontal Cortex; Risperidone; Schizophrenia; Sex Factors | 2007 |
Psychotic disorders, eating habits, and physical activity: who is ready for lifestyle changes?
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Clozapine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Exercise; Feeding Behavior; Female; Health Knowledge, Attitudes, Practice; Humans; Life Style; Male; Middle Aged; Nutrition Surveys; Olanzapine; Psychotic Disorders; Risperidone; Schizophrenia; Schizophrenic Psychology; Weight Gain | 2007 |
Correlation of physician and patient rated quality of life during antipsychotic treatment in outpatients with schizophrenia.
Topics: Adult; Ambulatory Care; Antipsychotic Agents; Benzodiazepines; Clozapine; Female; Humans; Male; Olanzapine; Patients; Physicians; Prospective Studies; Quality of Life; Risperidone; Schizophrenia; Self Concept; Surveys and Questionnaires | 2007 |
Comparative neurochemical changes associated with chronic administration of typical and atypical neuroleptics: implications in tardive dyskinesia.
Topics: Animals; Antipsychotic Agents; Body Weight; Chlorpromazine; Clozapine; Dopamine; Dyskinesia, Drug-Induced; Haloperidol; Male; Norepinephrine; Prosencephalon; Rats; Rats, Wistar; Risperidone; Serotonin | 2007 |
Reversal of PCP-induced learning and memory deficits in the Morris' water maze by sertindole and other antipsychotics.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Imidazoles; Indoles; Male; Maze Learning; Phencyclidine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Risperidone; Schizophrenic Psychology | 2007 |
Cognitive-disruptive effects of the psychotomimetic phencyclidine and attenuation by atypical antipsychotic medications in rats.
Topics: Animals; Antipsychotic Agents; Attention; Benzodiazepines; Clozapine; Cognition Disorders; Dibenzothiazepines; Disease Models, Animal; Dose-Response Relationship, Drug; Hallucinogens; Haloperidol; Impulsive Behavior; Male; Olanzapine; Phencyclidine; Quetiapine Fumarate; Rats; Rats, Wistar; Reaction Time; Risperidone; Schizophrenia | 2007 |
Disruption of the neurokinin-3 receptor (NK3) in mice leads to cognitive deficits.
Topics: Age Factors; Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Clozapine; Cognition Disorders; Conditioning, Operant; Dose-Response Relationship, Drug; Electric Stimulation; Gene Expression; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Receptors, Neurokinin-3; Reverse Transcriptase Polymerase Chain Reaction; Risperidone; Swimming; Time Factors; Weight Gain | 2007 |
The effects of chronic administration of established and putative antipsychotics on natural prepulse inhibition deficits in Brattleboro rats.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Arginine Vasopressin; Clozapine; Deamino Arginine Vasopressin; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Habituation, Psychophysiologic; Haloperidol; Neural Inhibition; Neurotensin; Rats; Rats, Brattleboro; Rats, Long-Evans; Rats, Mutant Strains; Reflex, Startle; Risperidone; Schizophrenia; Statistics, Nonparametric | 2007 |
Schizophrenic patients treated with clozapine or olanzapine perform better on theory of mind tasks than those treated with risperidone or typical antipsychotic medications.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brief Psychiatric Rating Scale; Clozapine; Cognition; Cognition Disorders; Diagnostic and Statistical Manual of Mental Disorders; Drug Prescriptions; Female; Humans; Male; Neuropsychological Tests; Olanzapine; Risperidone; Schizophrenia; Severity of Illness Index | 2007 |
Impairment in error monitoring predicts poor executive function in schizophrenia patients.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clozapine; Cognition Disorders; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Male; Memory, Short-Term; Neuropsychological Tests; Olanzapine; Piperazines; Reaction Time; Risperidone; Schizophrenia; Self Efficacy; Severity of Illness Index; Thiazoles | 2007 |
The influence of clozapine treatment and other antipsychotics on the 18 kDa translocator protein, formerly named the peripheral-type benzodiazepine receptor, and steroid production.
Topics: Adrenal Glands; Animals; Antipsychotic Agents; Brain; Cell Line; Clozapine; Corticosterone; Humans; Isoquinolines; Male; Mice; Mitochondria; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, GABA; Risperidone; Steroids; Sulpiride; Testis; Testosterone; Thioridazine | 2008 |
(+/-) Ketamine-induced prepulse inhibition deficits of an acoustic startle response in rats are not reversed by antipsychotics.
Topics: Animals; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Haloperidol; Ketamine; Lamotrigine; Male; Pyridines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Risperidone; Schizophrenia; Sulfonamides; Thiophenes; Triazines | 2007 |
In vitro effects of antipsychotics on human platelet adhesion and aggregation and plasma coagulation.
Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Blood Coagulation; Blood Platelets; Clozapine; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; In Vitro Techniques; Male; Middle Aged; Olanzapine; Partial Thromboplastin Time; Platelet Adhesiveness; Platelet Aggregation; Prothrombin Time; Risperidone; Thromboembolism; Venous Thrombosis | 2007 |
Atypical antipsychotic prescribing and diabetes.
Topics: Antipsychotic Agents; Blood Glucose; Clozapine; Diabetes Mellitus, Type 2; Humans; Risperidone; Schizophrenia | 2007 |
Safety and usage of atypical antipsychotic medicines in children: a nationwide prospective cohort study.
Topics: Adolescent; Antipsychotic Agents; Benzodiazepines; Child; Child, Preschool; Clozapine; Cohort Studies; Dibenzothiazepines; Drug Utilization; Female; Humans; Male; New Zealand; Olanzapine; Quetiapine Fumarate; Risperidone | 2007 |
Early use of clozapine for poorly responding first-episode psychosis.
Topics: Adolescent; Adult; Algorithms; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Drug Resistance; Female; Humans; Male; Middle Aged; Olanzapine; Psychiatric Status Rating Scales; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Schizophrenia | 2007 |
The use of atypical antipsychotics in French psychiatric hospitals.
Topics: Adult; Age Factors; Amisulpride; Antimanic Agents; Antiparkinson Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; France; Hospitals, Psychiatric; Humans; Male; Mental Disorders; Middle Aged; Olanzapine; Practice Patterns, Physicians'; Psychotic Disorders; Risperidone; Sex Factors; Sulpiride | 2007 |
Lu 35-138 ((+)-(S)-3-{1-[2-(1-acetyl-2,3-dihydro-1H-indol-3-yl)ethyl]-3,6-dihydro-2H-pyridin-4-yl}-6-chloro-1H-indole), a dopamine D4 receptor antagonist and serotonin reuptake inhibitor: characterisation of its in vitro profile and pre-clinical antipsych
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Animals, Outbred Strains; Benzodiazepines; Cebus; Citalopram; Clozapine; Cognition; Dihydropyridines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Haloperidol; Haplorhini; Humans; Indoles; Male; Mice; Molecular Structure; Motor Activity; Olanzapine; Piperazines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Dopamine D4; Risperidone; Selective Serotonin Reuptake Inhibitors; Sulfonamides | 2007 |
Characterization of atypical antipsychotic drugs by a late decrease of striatal alpha1 spectral power in the electropharmacogram of freely moving rats.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Corpus Striatum; Dibenzothiazepines; Dose-Response Relationship, Drug; Electroencephalography; Female; Hippocampus; Injections, Intraperitoneal; Male; Motor Activity; Movement; Olanzapine; Piperazines; Prefrontal Cortex; Quetiapine Fumarate; Rats; Rats, Inbred F344; Reticular Formation; Risperidone; Thiazoles; Time Factors | 2007 |
Isoflurane anesthesia inhibits clozapine- and risperidone-induced dopamine release and anesthesia-induced changes in dopamine metabolism was modified by fluoxetine in the rat striatum: an in vivo microdialysis study.
Topics: Anesthetics, Inhalation; Animals; Chromatography, High Pressure Liquid; Clozapine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Fluid; Fluoxetine; Isoflurane; Male; Microdialysis; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Synaptic Transmission | 2008 |
Sensitive liquid chromatography/tandem mass spectrometry method for the simultaneous determination of olanzapine, risperidone, 9-hydroxyrisperidone, clozapine, haloperidol and ziprasidone in rat brain tissue.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chromatography, Liquid; Clozapine; Haloperidol; Isoxazoles; Male; Olanzapine; Paliperidone Palmitate; Piperazines; Pyrimidines; Rats; Reproducibility of Results; Risperidone; Tandem Mass Spectrometry; Thiazoles | 2007 |
Long-term effects of JL 13, a potential atypical antipsychotic, on ionotropic glutamate receptors.
Topics: Animals; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Autoradiography; Benzodiazepines; Brain; Caudate Nucleus; Cerebral Cortex; Clozapine; Haloperidol; Hippocampus; Male; Olanzapine; Oxazepines; Piperazines; Putamen; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Risperidone; Tritium | 2007 |
Rehospitalization rates of patients with schizophrenia discharged on haloperidol, risperidone or clozapine.
Topics: Adult; Age of Onset; Antipsychotic Agents; Brazil; Clozapine; Epidemiologic Methods; Female; Haloperidol; Hospitals, Psychiatric; Humans; Length of Stay; Male; Patient Discharge; Patient Readmission; Risperidone; Schizophrenia; Time Factors | 2007 |
Show me the evidence: using number needed to treat.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Confidence Intervals; Data Interpretation, Statistical; Decision Making; Evidence-Based Medicine; Humans; Likelihood Functions; Olanzapine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Risk Assessment; Risperidone; Schizophrenia; Thiazoles; Treatment Outcome | 2007 |
Abnormally persistent latent inhibition induced by MK801 is reversed by risperidone and by positive modulators of NMDA receptor function: differential efficacy depending on the stage of the task at which they are administered.
Topics: Animals; Behavior, Animal; Clozapine; Conditioning, Psychological; Cycloserine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Emotions; Fluorobenzenes; Glycine; Glycine Agents; Inhibition, Psychological; Male; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Stress, Psychological; Thirst; Treatment Outcome | 2008 |
Ventricular arrhythmias and cerebrovascular events in the elderly using conventional and atypical antipsychotic medications.
Topics: Administration, Oral; Aged; Antipsychotic Agents; Aripiprazole; Arrhythmias, Cardiac; Benzodiazepines; Clozapine; Databases, Factual; Dementia; Dibenzothiazepines; Drug Utilization Review; Health Services for the Aged; Humans; Olanzapine; Pharmaceutical Services; Piperazines; Quetiapine Fumarate; Quinolones; Risk Assessment; Risperidone; Stroke; Thiazoles; Treatment Outcome | 2007 |
The Schizophrenia Outpatient Health Outcomes (SOHO) study: 3-year results of antipsychotic treatment discontinuation and related clinical factors in Spain.
Topics: Administration, Oral; Adult; Ambulatory Care; Antipsychotic Agents; Benzodiazepines; Clozapine; Delayed-Action Preparations; Dibenzothiazepines; Drug Administration Schedule; Female; Follow-Up Studies; Health Care Surveys; Humans; Longitudinal Studies; Male; Olanzapine; Outcome Assessment, Health Care; Patient Dropouts; Prospective Studies; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Spain; Survival Analysis; Time Factors; Treatment Outcome | 2008 |
Clozapine and olanzapine but not risperidone impair the pre-frontal striatal system in relation to egocentric spatial orientation in a Y-maze.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Benzodiazepines; Choice Behavior; Clozapine; Cues; Dopamine Antagonists; Male; Neostriatum; Olanzapine; Orientation; Prefrontal Cortex; Psychomotor Performance; Rats; Rats, Long-Evans; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Space Perception | 2007 |
[22q11.2 deletion and schizophrenia in childhood and adolescence].
Topics: Adolescent; Antipsychotic Agents; Calcium; Child; Chromosome Deletion; Chromosomes, Human, Pair 22; Clozapine; Developmental Disabilities; Female; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Hypocalcemia; Male; Risperidone; Schizophrenia; Schizophrenic Psychology; Seizures | 2007 |
The chakragati mouse shows deficits in prepulse inhibition of acoustic startle and latent inhibition.
Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Clozapine; Conditioning, Psychological; Disease Models, Animal; Electroshock; Female; Haloperidol; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Reflex, Startle; Risperidone; Schizophrenia | 2008 |
Chronic antipsychotic drug administration alters the expression of neuregulin 1beta, ErbB2, ErbB3, and ErbB4 in the rat prefrontal cortex and hippocampus.
Topics: Animals; Antibody Specificity; Antipsychotic Agents; Blotting, Western; Clozapine; ErbB Receptors; Glycoproteins; Haloperidol; Hippocampus; Immunohistochemistry; Male; Nerve Tissue Proteins; Neuregulin-1; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, ErbB-2; Receptor, ErbB-3; Receptor, ErbB-4; Risperidone | 2008 |
Time to rehospitalization of clozapine versus risperidone in the naturalistic treatment of comorbid alcohol use disorder and schizophrenia.
Topics: Adolescent; Adult; Alcoholism; Antipsychotic Agents; Clozapine; Diagnosis, Dual (Psychiatry); Female; Humans; Male; Middle Aged; Patient Readmission; Prospective Studies; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Socioeconomic Factors; Survival Analysis | 2008 |
Clozapine may partially compensate for task-related brain perfusion abnormalities in risperidone-resistant schizophrenia patients.
Topics: Adult; Antipsychotic Agents; Brain; Cerebrovascular Disorders; Clozapine; Cognition; Drug Resistance; Female; Haloperidol; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Psychiatric Status Rating Scales; Retrospective Studies; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Treatment Failure | 2008 |
A preliminary investigation into the effects of antipsychotics on sub-chronic phencyclidine-induced deficits in attentional set-shifting in female rats.
Topics: Animals; Antipsychotic Agents; Attention; Clozapine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Habituation, Psychophysiologic; Haloperidol; Phencyclidine; Pilot Projects; Rats; Rats, Inbred Strains; Risperidone; Set, Psychology; Sex Factors; Statistics, Nonparametric | 2008 |
Combined low-dose clozapine with low-dose aripiprazole in a schizophrenic patient.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Basal Ganglia Diseases; Clozapine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Guidelines as Topic; Humans; Male; Piperazines; Quinolones; Risk Assessment; Risperidone; Schizophrenia | 2009 |
Using pharmacokinetic-pharmacodynamic modelling as a tool for prediction of therapeutic effective plasma levels of antipsychotics.
Topics: Administration, Oral; Animals; Antipsychotic Agents; Basal Ganglia; Behavior, Animal; Benzodiazepines; Binding, Competitive; Clozapine; Conditioning, Psychological; Dopamine Antagonists; Haloperidol; Imidazoles; Indoles; Injections, Subcutaneous; Male; Models, Biological; Olanzapine; Protein Binding; Raclopride; Rats; Rats, Wistar; Receptors, Dopamine D2; Reproducibility of Results; Risperidone | 2008 |
Comparing the use and discontinuation of antipsychotics in clinical practice: an observational study.
Topics: Adult; Aged; Amisulpride; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clozapine; Dibenzothiazepines; Drug Administration Schedule; Female; Humans; Male; Medical Records; Middle Aged; Olanzapine; Patient Admission; Polypharmacy; Practice Patterns, Physicians'; Quetiapine Fumarate; Research Design; Retrospective Studies; Risperidone; Schizophrenia; Scotland; Sulpiride | 2008 |
Treatment compliance of outpatients with schizophrenia: patient's attitudes, demographic, clinical and therapeutic variables.
Topics: Administration, Oral; Adult; Age Factors; Ambulatory Care; Antipsychotic Agents; Clozapine; Cross-Sectional Studies; Delayed-Action Preparations; Female; Fluphenazine; Haloperidol; Health Knowledge, Attitudes, Practice; Humans; Long-Term Care; Male; Middle Aged; Patient Compliance; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Yugoslavia | 2008 |
[Prescription of traditional neuroleptics in the remission period for schizophrenic patients with excess of body mass caused by atypical antipsychotics].
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Clozapine; Drug Prescriptions; Female; Follow-Up Studies; Haloperidol; Humans; Male; Mental Status Schedule; Olanzapine; Overweight; Risperidone; Schizophrenia; Treatment Outcome; Trifluoperazine | 2007 |
[A naturalistic, observational study of outpatients with schizophrenia: efficacy and safety results after 6 months. The International Schizophrenia Outpatient Health Outcomes study, IC-SOHO].
Topics: Adult; Aggression; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clozapine; Dibenzothiazepines; Erectile Dysfunction; Female; Galactorrhea; Gynecomastia; Haloperidol; Humans; Hungary; International Cooperation; Libido; Male; Menstruation Disturbances; Middle Aged; Olanzapine; Outpatients; Patient Admission; Patient Compliance; Prospective Studies; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index | 2007 |
Did CATIE influence antipsychotic use?
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Drug Therapy; Haloperidol; Humans; Olanzapine; Perphenazine; Piperazines; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Schizophrenia; Thiazoles | 2008 |
Excess of transmission of the G allele of the -1438A/G polymorphism of the 5-HT2A receptor gene in patients with schizophrenia responsive to antipsychotics.
Topics: Adenine; Adult; Algeria; Antipsychotic Agents; Clozapine; Diagnostic and Statistical Manual of Mental Disorders; Family; Female; Gene Frequency; Guanine; Haloperidol; Humans; Lithium Carbonate; Male; Patient Selection; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Receptor, Serotonin, 5-HT2A; Risperidone; Schizophrenia; Treatment Outcome | 2008 |
Caution is still needed when prescribing atypical antipsychotics.
Topics: Antipsychotic Agents; Catatonia; Clozapine; Humans; Neuroleptic Malignant Syndrome; Risperidone | 2008 |
Spatial working memory and problem solving in schizophrenia: the effect of symptom stabilization with atypical antipsychotic medication.
Topics: Adult; Antipsychotic Agents; Clozapine; Cognition Disorders; Control Groups; Female; Follow-Up Studies; Hospitalization; Humans; Male; Maze Learning; Memory; Memory Disorders; Memory, Short-Term; Neuropsychological Tests; Problem Solving; Psychometrics; Risperidone; Schizophrenia; Schizophrenic Psychology; Space Perception; Treatment Outcome | 2008 |
Rechallenging with clozapine following neutropenia: treatment options for refractory schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Drug Resistance; Drug Therapy, Combination; Humans; Male; Middle Aged; Neutropenia; Recurrence; Risperidone; Schizophrenia, Paranoid; Severity of Illness Index | 2008 |
Polymorphisms in human endogenous retrovirus K-18 and risk of type 2 diabetes in individuals with schizophrenia.
Topics: 3' Untranslated Regions; Antigens, CD; Antipsychotic Agents; Benzodiazepines; CD48 Antigen; Chromosomes, Human, Pair 1; Clozapine; Diabetes Mellitus, Type 2; Diagnostic and Statistical Manual of Mental Disorders; Endogenous Retroviruses; Female; Haplotypes; Humans; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Olanzapine; Polymorphism, Genetic; Risk Factors; Risperidone; Schizophrenia; Signaling Lymphocytic Activation Molecule Associated Protein | 2008 |
A comparison of the discriminative stimulus properties of the atypical antipsychotic drug clozapine in DBA/2 and C57BL/6 inbred mice.
Topics: Amphetamine; Animals; Antipsychotic Agents; Benzodiazepines; Brain; Clozapine; Discrimination Learning; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Olanzapine; Risperidone | 2008 |
Role of serotonin-1A receptors in the action of antipsychotic drugs: comparison of prepulse inhibition studies in mice and rats and relevance for human pharmacology.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Haloperidol; Inhibition, Psychological; Male; Mice; Mice, Inbred Strains; Olanzapine; Piperazines; Quinolones; Rats; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Reflex, Startle; Risperidone; Serotonin Receptor Agonists; Species Specificity | 2008 |
Amisulpride the 'atypical' atypical antipsychotic--comparison to haloperidol, risperidone and clozapine.
Topics: Amisulpride; Amphetamine; Animals; Antipsychotic Agents; Basal Ganglia; Behavior, Animal; Blood-Brain Barrier; Brain; Clozapine; Conditioning, Psychological; Haloperidol; Male; Models, Animal; Motor Activity; Phencyclidine; Prefrontal Cortex; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Serotonin; Risperidone; Sulpiride | 2008 |
Effect of muscarinic receptor agonists xanomeline and sabcomeline on acetylcholine and dopamine efflux in the rat brain; comparison with effects of 4-[3-(4-butylpiperidin-1-yl)-propyl]-7-fluoro-4H-benzo[1,4]oxazin-3-one (AC260584) and N-desmethylclozapine
Topics: Acetylcholine; Animals; Antipsychotic Agents; Benzoxazines; Brain; Clozapine; Dopamine; Drug Synergism; Imines; Male; Nucleus Accumbens; Pirenzepine; Prefrontal Cortex; Pyridines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptor, Muscarinic M4; Risperidone; Thiadiazoles | 2008 |
Antipsychotics possessing antidepressive efficacy increase Golf protein in rat striatum.
Topics: Amisulpride; Animals; Antipsychotic Agents; Benzodiazepines; Blotting, Western; Clozapine; Corpus Striatum; Depressive Disorder; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits; Haloperidol; Injections, Intraperitoneal; Male; Olanzapine; Rats; Rats, Wistar; Risperidone; Sulpiride; Time Factors | 2008 |
Weight gain in children and adolescents during 45 weeks treatment with clozapine, olanzapine and risperidone.
Topics: Adolescent; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Child; Clozapine; Female; Hospitals, Psychiatric; Humans; Inpatients; Male; Olanzapine; Patch-Clamp Techniques; Risk Factors; Risperidone; Weight Gain; Young Adult | 2008 |
LORETA functional imaging in antipsychotic-naive and olanzapine-, clozapine- and risperidone-treated patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brain; Brain Mapping; Clozapine; Electroencephalography; Female; Humans; Male; Olanzapine; Reference Values; Risperidone; Schizophrenia; Signal Processing, Computer-Assisted; Young Adult | 2008 |
Treatment of generalized tardive dystonia with clozapine.
Topics: Adult; Antipsychotic Agents; Clozapine; Dyskinesia, Drug-Induced; Dystonic Disorders; Follow-Up Studies; Hospitalization; Humans; Male; Psychiatric Status Rating Scales; Receptors, GABA; Receptors, Muscarinic; Risperidone | 2008 |
Cardiac-related findings at autopsy in people with severe mental illness treated with clozapine or risperidone.
Topics: Adult; Antipsychotic Agents; Body Mass Index; Case-Control Studies; Cause of Death; Clozapine; Coronary Artery Disease; Coronary Vessels; Endomyocardial Fibrosis; Female; Humans; Hypertrophy, Left Ventricular; Hypertrophy, Right Ventricular; Male; Maryland; Middle Aged; Myocardium; Risk Factors; Risperidone; Schizophrenia; Waist-Hip Ratio | 2009 |
Antipsychotic-induced body weight gain: predictors and a systematic categorization of the long-term weight course.
Topics: Adolescent; Adult; Age Factors; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Body Weight; Clozapine; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Olanzapine; Parents; Retrospective Studies; Risk Factors; Risperidone; Sex Factors; Smoking; Time Factors; Weight Gain; Young Adult | 2009 |
Extreme elevation of creatinine phosphokinase levels in neuroleptic malignant syndrome associated with atypical antipsychotics.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Clozapine; Creatine Kinase; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Male; Myocardial Infarction; Neuroleptic Malignant Syndrome; Piperazines; Quinolones; Risperidone; Schizophrenia; Valproic Acid | 2009 |
Atypical antipsychotics suppress production of proinflammatory cytokines and up-regulate interleukin-10 in lipopolysaccharide-treated mice.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Cytokines; Haloperidol; Interleukin-10; Interleukin-6; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Olanzapine; Poly I-C; Risperidone; Serotonin Antagonists; Tumor Necrosis Factor-alpha | 2009 |
Reasons for discontinuing clozapine: matched, case-control comparison with risperidone long-acting injection.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Case-Control Studies; Cause of Death; Clozapine; Delayed-Action Preparations; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Risperidone; Schizophrenia; Treatment Refusal; Young Adult | 2009 |
Contribution of leptin to the formation of neuroleptic obesity in patients with schizophrenia during antipsychotic therapy.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Female; Humans; Leptin; Male; Obesity; Olanzapine; Risperidone; Schizophrenia, Paranoid; Sex Factors; Young Adult | 2008 |
Antipsychotics affect multiple calcium calmodulin dependent proteins.
Topics: Animals; Antipsychotic Agents; Calcineurin; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Clozapine; Corpus Striatum; Dopamine Antagonists; Haloperidol; Male; Psychotropic Drugs; Raclopride; Rats; Rats, Sprague-Dawley; Risperidone; RNA, Messenger | 2009 |
Drug prescription patterns in schizophrenia outpatients: analysis of data from a German health insurance fund.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Drug Prescriptions; Drug Therapy, Combination; Female; Follow-Up Studies; Germany; Humans; Insurance, Health; Male; Middle Aged; Olanzapine; Outpatients; Practice Patterns, Physicians'; Prescription Drugs; Retrospective Studies; Risperidone; Schizophrenia; Severity of Illness Index; Sex Factors; Young Adult | 2009 |
Haloperidol changes mRNA expression of a QKI splice variant in human astrocytoma cells.
Topics: Alternative Splicing; Antipsychotic Agents; Aripiprazole; Astrocytoma; Benzodiazepines; Cell Line, Tumor; Clozapine; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Haloperidol; Humans; Olanzapine; Piperazines; Quinolones; Receptors, Dopamine D2; Reverse Transcriptase Polymerase Chain Reaction; Risperidone; RNA-Binding Proteins; RNA, Messenger; Time Factors | 2009 |
[Peculiarities of neuroleptic syndrome in women treated with typical and atypical neuroleptics].
Topics: Adult; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Haloperidol; Humans; Neuroleptic Malignant Syndrome; Risperidone; Sexuality; Treatment Outcome | 2009 |
Can atypical antipsychotics improve tardive dyskinesia associated with other atypical antipsychotics? Case report and brief review of the literature.
Topics: Adult; Anti-Dyskinesia Agents; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dyskinesia, Drug-Induced; Female; Humans; Olanzapine; Quetiapine Fumarate; Risperidone; Schizophrenia, Paranoid | 2010 |
Differences among conventional, atypical and novel putative D(2)/5-HT(1A) antipsychotics on catalepsy-associated behaviour in cynomolgus monkeys.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Aripiprazole; Benzamides; Benzodiazepines; Benzoxazoles; Catalepsy; Clozapine; Dibenzothiazepines; Dioxanes; Dopamine Antagonists; Female; Haloperidol; Macaca fascicularis; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Remoxipride; Risperidone; Serotonin Receptor Agonists; Thiazoles; Tropanes; Video Recording | 2009 |
Neuroleptics: necrotising enterocolitis.
Topics: Antipsychotic Agents; Atropine; Benzodiazepines; Clozapine; Drug Therapy, Combination; Enterocolitis, Necrotizing; France; Humans; Risperidone; Sulpiride | 2009 |
Antipsychotic switching: results from a one-year prospective, observational study of patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Cohort Studies; Dibenzothiazepines; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Olanzapine; Quetiapine Fumarate; Risperidone; Schizophrenia; Withholding Treatment | 2009 |
Drug-induced sialorrhoea and excessive saliva accumulation.
Topics: Antipsychotic Agents; Benzodiazepines; Cholinesterase Inhibitors; Clozapine; Deglutition Disorders; Donepezil; Galantamine; Humans; Hypnotics and Sedatives; Indans; Phenylcarbamates; Pilocarpine; Piperidines; Quality of Life; Risperidone; Rivastigmine; Sialorrhea | 2009 |
The effects of the second generation antipsychotics and a typical neuroleptic on collagen-induced platelet aggregation in vitro.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Collagen; Female; Haloperidol; Humans; In Vitro Techniques; Male; Olanzapine; Platelet Activation; Platelet Aggregation; Risperidone | 2010 |
[Complex therapy of schizophrenia].
Topics: Adolescent; Adult; Antipsychotic Agents; Art Therapy; Benzodiazepines; Clinical Trials as Topic; Clozapine; Cognitive Behavioral Therapy; Combined Modality Therapy; Dance Therapy; Dibenzothiazepines; Female; Haloperidol; Humans; Male; Middle Aged; Music Therapy; Occupational Therapy; Olanzapine; Psychotherapy; Quetiapine Fumarate; Retrospective Studies; Risperidone; Schizophrenia; Schizophrenic Psychology; Single-Blind Method; Suicide; Treatment Outcome; Young Adult | 2009 |
Different antipsychotics elicit different effects on magnocellular oxytocinergic and vasopressinergic neurons as revealed by Fos immunohistochemistry.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Haloperidol; Hypothalamus; Immunohistochemistry; Male; Neurons; Olanzapine; Oxytocin; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Risperidone; Supraoptic Nucleus; Vasopressins | 2010 |
In vitro and in vivo evaluation of the inhibition potential of risperidone toward clozapine biotransformation.
Topics: Adult; Antipsychotic Agents; Biotransformation; Chromatography, High Pressure Liquid; Clozapine; Cytochrome P-450 Enzyme System; Drug Combinations; Drug Interactions; Female; Fluvoxamine; Humans; Ketoconazole; Male; Microsomes, Liver; Middle Aged; Risperidone; Schizophrenia; Young Adult | 2009 |
Health-related quality of life (HRQL) and continuous antipsychotic treatment: 3-year results from the Schizophrenia Health Outcomes (SOHO) study.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Confidence Intervals; Female; Health Status Indicators; Humans; Longitudinal Studies; Male; Models, Economic; Multivariate Analysis; Olanzapine; Outpatients; Quality of Life; Quality-Adjusted Life Years; Risperidone; Schizophrenia; Spain; Time Factors | 2009 |
Chronic administration of atypical antipsychotics improves behavioral and synaptic defects of STOP null mice.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Drug Evaluation, Preclinical; Hippocampus; Male; Mice; Mice, Knockout; Microtubule-Associated Proteins; Neuronal Plasticity; Risperidone | 2010 |
The combined use of risperidone long-acting injection and clozapine in patients with schizophrenia non-adherent to clozapine: a case series.
Topics: Adult; Antipsychotic Agents; Clozapine; Delayed-Action Preparations; Drug Therapy, Combination; Female; Hospitalization; Humans; Injections; Male; Patient Compliance; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenia, Paranoid; Schizophrenic Psychology; Social Behavior; Treatment Outcome; Young Adult | 2010 |
Do antipsychotic medications reduce or increase mortality in schizophrenia? A critical appraisal of the FIN-11 study.
Topics: Adult; Antipsychotic Agents; Clozapine; Dibenzothiazepines; Female; Finland; Haloperidol; Humans; Male; Perphenazine; Quetiapine Fumarate; Risperidone; Schizophrenia; Suicide; Survival Rate | 2010 |
Functional SNPs in genes encoding the 5-HT2A receptor modify the affinity and potency of several atypical antipsychotic drugs.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Dibenzothiazepines; Drug Resistance; HEK293 Cells; Humans; Mutagenesis, Site-Directed; Neuroleptic Malignant Syndrome; Nursing Research; Olanzapine; Pharmacogenetics; Piperazines; Polymorphism, Single Nucleotide; Quetiapine Fumarate; Quinolones; Receptor, Serotonin, 5-HT2A; Risperidone; Thiazoles | 2011 |
Evidence-based use of second-generation antipsychotics in a state Medicaid pediatric population, 2001-2005.
Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Child; Child, Preschool; Clozapine; Dibenzothiazepines; Drug Utilization; Evidence-Based Medicine; Female; Humans; Infant; Insurance Claim Review; Male; Medicaid; Mental Disorders; Off-Label Use; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Thiazoles; United States; United States Food and Drug Administration | 2010 |
An examination of the relative contribution of saturation and selective attention to memory deficits in patients with recent-onset schizophrenia and their unaffected parents.
Topics: Age of Onset; Antipsychotic Agents; Attention; Clozapine; Dibenzothiazepines; Female; Humans; Male; Memory Disorders; Memory, Short-Term; Neuropsychological Tests; Parents; Quetiapine Fumarate; Risperidone; Schizophrenia; Severity of Illness Index; Young Adult | 2010 |
Patterns of discontinuation of atypical antipsychotics in the province of Québec: A retrospective prescription claims database analysis.
Topics: Adult; Age Distribution; Antipsychotic Agents; Benzodiazepines; Clozapine; Cohort Studies; Databases, Factual; Dibenzothiazepines; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization; Drug Utilization Review; Female; Humans; Kaplan-Meier Estimate; Male; Mental Disorders; Middle Aged; Olanzapine; Patient Compliance; Quebec; Quetiapine Fumarate; Registries; Retrospective Studies; Risperidone; Sex Distribution; Young Adult | 2010 |
Dopamine release induced by atypical antipsychotics in prefrontal cortex requires 5-HT(1A) receptors but not 5-HT(2A) receptors.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Dopamine; Dopamine Antagonists; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Models, Animal; Olanzapine; Prefrontal Cortex; Quinolines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, G-Protein-Coupled; Risperidone; Schizophrenia | 2010 |
Remission of drug-induced hepatitis after switching from risperidone to paliperidone.
Topics: Adult; Antipsychotic Agents; Biotransformation; Chemical and Drug Induced Liver Injury; Clozapine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Isoxazoles; Liver Function Tests; Paliperidone Palmitate; Pyrimidines; Reference Values; Risperidone; Schizophrenia | 2010 |
Dietary saturated fat intake and glucose metabolism impairments in nondiabetic, nonobese patients with schizophrenia on clozapine or risperidone.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Blood Glucose; Clozapine; Cross-Sectional Studies; Diet Records; Dietary Fats; Eating; Female; Food Preferences; Glucose; Glucose Tolerance Test; Humans; Insulin Resistance; Lipid Metabolism; Male; Risperidone; Schizophrenia | 2010 |
The first- and second-generation antipsychotic drugs affect ADP-induced platelet aggregation.
Topics: Adenosine Diphosphate; Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Female; Haloperidol; Humans; Male; Olanzapine; Platelet Activation; Platelet Aggregation; Risperidone | 2010 |
The role of CYP2D6 and TaqI A polymorphisms in malignant neuroleptic syndrome: two case reports with three episodes.
Topics: Adult; Alleles; Antipsychotic Agents; Bipolar Disorder; Clozapine; Cytochrome P-450 CYP2D6; Dibenzothiazepines; Drug Therapy, Combination; Fluphenazine; Genetic Carrier Screening; Genotype; Haloperidol; Humans; Lithium Carbonate; Male; Neuroleptic Malignant Syndrome; Perazine; Polymorphism, Genetic; Psychotic Disorders; Quetiapine Fumarate; Receptors, Dopamine D2; Recurrence; Risperidone | 2010 |
Dopamine receptor D2 gene is associated with weight gain in schizophrenic patients under long-term atypical antipsychotic treatment.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Body Weight; Clozapine; Female; Genes; Genotype; Haplotypes; Humans; Long-Term Care; Male; Middle Aged; Odds Ratio; Olanzapine; Receptors, Dopamine D2; Risperidone; Schizophrenia; Weight Gain | 2010 |
The antipsychotics olanzapine, risperidone, clozapine, and haloperidol are D2-selective ex vivo but not in vitro.
Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Clozapine; Dose-Response Relationship, Drug; Haloperidol; Humans; In Vitro Techniques; Male; Olanzapine; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Risperidone; Tritium; Vitamin K 1 | 2010 |
A parametric study of the acute effects of antipsychotic drugs on glucose sensitivity in an animal model.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Blood Glucose; Clozapine; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Glucose Tolerance Test; Haloperidol; Insulin; Insulin Resistance; Rats; Rats, Sprague-Dawley; Risperidone | 2010 |
Withdrawal-emergent respiratory dyskinesia with risperidone treated with clozapine.
Topics: Anti-Dyskinesia Agents; Antipsychotic Agents; Clozapine; Dyskinesia, Drug-Induced; Female; Humans; Middle Aged; Respiration Disorders; Risperidone; Schizophrenia; Substance Withdrawal Syndrome; Treatment Outcome | 2010 |
Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Carnitine; Clozapine; Energy Metabolism; Fatty Acids, Nonesterified; Female; Haloperidol; Insulin Resistance; Lipolysis; Male; Malonyl Coenzyme A; Mice; Olanzapine; Piperazines; Rats; Rats, Sprague-Dawley; Risperidone; Thiazoles; Vitamin B Complex | 2012 |
[Effect of side-effects and complications caused by atypical neuroleptics on the effectiveness of therapy in patients with schizophrenia].
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Quetiapine Fumarate; Risperidone; Schizophrenia; Treatment Outcome | 2010 |
Berberine inhibits SREBP-1-related clozapine and risperidone induced adipogenesis in 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adipogenesis; Animals; Berberine; Cell Differentiation; Cell Survival; Clozapine; Mice; Risperidone; RNA, Messenger; Sterol Regulatory Element Binding Protein 1 | 2010 |
Effect of 'chronic' versus 'acute' ketamine administration and its 'withdrawal' effect on behavioural alterations in mice: implications for experimental psychosis.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Clozapine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Haloperidol; Ketamine; Male; Mice; Motor Activity; Psychotic Disorders; Random Allocation; Risperidone; Schizophrenia; Substance Withdrawal Syndrome; Swimming | 2011 |
[Catatonic dilemma in a schizoaffective patient with combined lithium-risperidone administration].
Topics: Antimanic Agents; Antipsychotic Agents; Brain; Catatonia; Clozapine; Diagnosis, Differential; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Electroencephalography; Humans; Hypnotics and Sedatives; Lithium Carbonate; Long-Term Care; Lorazepam; Male; Middle Aged; Psychotic Disorders; Risperidone; Serotonin | 2010 |
Clozapine and other competitive antagonists reactivate risperidone-inactivated h5-HT7 receptors: radioligand binding and functional evidence for GPCR homodimer protomer interactions.
Topics: Binding, Competitive; Biosensing Techniques; Cell Line; Clozapine; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Isoxazoles; Paliperidone Palmitate; Protein Binding; Protein Multimerization; Protein Subunits; Pyrimidines; Radioligand Assay; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Transfection | 2010 |
Effect of adjunctive duloxetine on the plasma concentrations of clozapine, olanzapine, and risperidone in patients with psychotic disorders.
Topics: Adult; Benzodiazepines; Clozapine; Drug Interactions; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Middle Aged; Olanzapine; Psychotic Disorders; Risperidone; Thiophenes; Young Adult | 2010 |
Experimental analysis and modelling of in vitro HUVECs proliferation in the presence of various types of drugs.
Topics: Captopril; Cell Proliferation; Clozapine; Drug Evaluation, Preclinical; Endothelial Cells; Flow Cytometry; Humans; Lovastatin; Models, Biological; Risperidone | 2010 |
Clock genes and body composition in patients with schizophrenia under treatment with antipsychotic drugs.
Topics: Adult; Age Factors; Alleles; Amisulpride; Anthropometry; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Body Composition; Body Mass Index; CLOCK Proteins; Clozapine; Dibenzothiazepines; Drug Therapy, Combination; Female; Genetic Association Studies; Genetic Carrier Screening; Genotype; Humans; Long-Term Care; Male; Middle Aged; Mutation, Missense; Olanzapine; Period Circadian Proteins; Piperazines; Polymorphism, Single Nucleotide; Psychotic Disorders; Quetiapine Fumarate; Quinolones; Receptor, Melanocortin, Type 3; Receptors, Glucocorticoid; Receptors, Leptin; Risperidone; Schizophrenia; Sex Factors; Sulpiride; Syndecan-3 | 2011 |
Risperidone-induced inactivation and clozapine-induced reactivation of rat cortical astrocyte 5-hydroxytryptamine₇ receptors: evidence for in situ G protein-coupled receptor homodimer protomer cross-talk.
Topics: Animals; Astrocytes; Cell Line; Cerebral Cortex; Clozapine; Dose-Response Relationship, Drug; Humans; Rats; Receptor Cross-Talk; Receptors, G-Protein-Coupled; Risperidone; Serotonin; Serotonin Antagonists | 2011 |
Pharmacological characterizations of memantine-induced disruption of prepulse inhibition of the acoustic startle response in mice: involvement of dopamine D2 and 5-HT2A receptors.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Benzazepines; Clozapine; Dopamine Agents; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Ketanserin; Male; Memantine; Mice; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Reflex, Startle; Risperidone; Sensory Gating | 2011 |
Dose-related effects of clozapine and risperidone on the pattern of brain regional serotonin and dopamine metabolism and on tests related to extrapyramidal functions in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Behavior; Brain; Clozapine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Extrapyramidal Tracts; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Risperidone; Serotonin; Serotonin Antagonists; Tryptophan; Visual Cortex | 2010 |
Association between HTR2C polymorphisms and metabolic syndrome in patients with schizophrenia treated with atypical antipsychotics.
Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Clozapine; Female; Gene Frequency; Genetic Linkage; Genetic Markers; Genetic Predisposition to Disease; Genetic Variation; Genotype; Haplotypes; Homozygote; Humans; Male; Metabolic Syndrome; Middle Aged; Olanzapine; Polymorphism, Single Nucleotide; Risk Factors; Risperidone; Schizophrenia; Sex Factors | 2011 |
Metabolic syndrome with different antipsychotics: a multicentre cross-sectional study.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Chi-Square Distribution; Clopenthixol; Clozapine; Cross-Sectional Studies; Female; Humans; Male; Metabolic Syndrome; Middle Aged; Olanzapine; Prevalence; Risk Assessment; Risk Factors; Risperidone; Schizophrenia; Turkey; Young Adult | 2010 |
Effects of antipsychotics on the serum BDNF levels in schizophrenia.
Topics: Adult; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Clozapine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Retrospective Studies; Risperidone; Schizophrenia, Paranoid | 2011 |
Stability of medication in early psychosis: a comparison between second-generation and low-dose first-generation antipsychotics.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Chi-Square Distribution; Clopenthixol; Clozapine; Female; Humans; Imidazoles; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Olanzapine; Perphenazine; Psychotic Disorders; Risperidone; Statistics, Nonparametric; Time Factors; Young Adult | 2009 |
Impact of apolipoprotein A5 (APOA5) polymorphisms on serum triglyceride levels in schizophrenic patients under long-term atypical antipsychotic treatment.
Topics: Adult; Antipsychotic Agents; Apolipoprotein A-V; Apolipoproteins A; Benzodiazepines; Clozapine; Female; Haplotypes; Humans; Hypertriglyceridemia; Male; Middle Aged; Olanzapine; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Risperidone; Schizophrenia; Taiwan; Triglycerides | 2012 |
Prevalence and severity of antipsychotic related constipation in patients with schizophrenia: a retrospective descriptive study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Aripiprazole; Clozapine; Constipation; Enema; Fecal Impaction; Female; Gastrointestinal Agents; Humans; Lactulose; Male; Middle Aged; Piperazines; Polyethylene Glycols; Prevalence; Quinolones; Retrospective Studies; Risperidone; Schizophrenia; Severity of Illness Index; Young Adult | 2011 |
Role of the dopamine transporter in mediating the neuroleptic-induced reduction of tyrosine hydroxylase-immunoreactive midbrain neurons.
Topics: Animals; Antipsychotic Agents; Clozapine; Dopamine Plasma Membrane Transport Proteins; Haloperidol; Immunohistochemistry; Mesencephalon; Neurons; Rats; Rats, Sprague-Dawley; Risperidone; Tyrosine 3-Monooxygenase | 2011 |
Time course of the attenuation effect of repeated antipsychotic treatment on prepulse inhibition disruption induced by repeated phencyclidine treatment.
Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Clozapine; Dibenzothiazepines; Drug Interactions; Hallucinogens; Haloperidol; Humans; Male; Models, Animal; Motor Activity; Phencyclidine; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Reflex, Startle; Risperidone | 2011 |
Risk of arrest in persons with schizophrenia and bipolar disorder in a Florida Medicaid program: the role of atypical antipsychotics, conventional neuroleptics, and routine outpatient behavioral health services.
Topics: Adolescent; Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disorder; Clozapine; Crime; Delayed-Action Preparations; Dibenzothiazepines; Female; Florida; Humans; Isoxazoles; Male; Medicaid; Middle Aged; Olanzapine; Outpatients; Paliperidone Palmitate; Piperazines; Propensity Score; Pyrimidines; Quetiapine Fumarate; Quinolones; Risk Factors; Risperidone; Schizophrenia; Treatment Outcome; United States; Young Adult | 2011 |
Sorption of emerging trace organic compounds onto wastewater sludge solids.
Topics: Adsorption; Amitriptyline; Clozapine; Cosmetics; Household Products; Hydroxyzine; Organic Chemicals; Pharmaceutical Preparations; Risperidone; Sewage; Verapamil; Waste Disposal, Fluid; Water Pollutants, Chemical | 2011 |
Time to rehospitalization in patients with schizophrenia discharged on first generation antipsychotics, non-clozapine second generation antipsychotics, or clozapine.
Topics: Adult; Antipsychotic Agents; Clozapine; Female; Humans; Longitudinal Studies; Male; Middle Aged; Observation; Patient Discharge; Patient Readmission; Retrospective Studies; Risperidone; Schizophrenia; Survival Analysis; Time Factors | 2011 |
Misdiagnosis and exacerbation of unusual obsessive-compulsive disorder presentation with risperidone and clozapine in an adolescent girl - A case report.
Topics: Adolescent; Antipsychotic Agents; Clozapine; Diagnostic Errors; Female; Fluvoxamine; Humans; Obsessive-Compulsive Disorder; Psychotic Disorders; Risperidone | 2011 |
Nocturnal enuresis in patients taking clozapine, risperidone, olanzapine and quetiapine: comparative cohort study.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Child; Clozapine; Cohort Studies; Dibenzothiazepines; Female; Humans; Incidence; Male; Middle Aged; New Zealand; Nocturnal Enuresis; Olanzapine; Product Surveillance, Postmarketing; Quetiapine Fumarate; Risperidone; Urban Population; Young Adult | 2011 |
Antipsychotic drugs suppress the AKT/NF-κB pathway and regulate the differentiation of T-cell subsets.
Topics: Antipsychotic Agents; CD4-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Clozapine; GATA3 Transcription Factor; Haloperidol; Humans; NF-kappa B; Oncogene Protein v-akt; Risperidone; Schizophrenia; Signal Transduction; T-Box Domain Proteins; T-Lymphocyte Subsets; Th1-Th2 Balance | 2011 |
Differences in craving for cannabis between schizophrenia patients using risperidone, olanzapine or clozapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Cannabis; Clozapine; Cohort Studies; Dopamine; Female; Humans; Longitudinal Studies; Male; Marijuana Abuse; Olanzapine; Receptors, Dopamine D1; Receptors, Dopamine D2; Risperidone; Schizophrenia | 2012 |
[Clinical characteristics of cannabis-induced schizophrenia spectrum disorder].
Topics: Adolescent; Adult; Aggression; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Dibenzothiazepines; Hallucinations; Haloperidol; Humans; Hungary; Male; Marijuana Abuse; Olanzapine; Paranoid Disorders; Piperazines; Psychomotor Performance; Quetiapine Fumarate; Quinolones; Retrospective Studies; Risperidone; Schizophrenia; Schizophrenic Psychology | 2011 |
Effect of antipsychotic-induced hyperprolactinemia on anthropometric measures, insulin sensitivity and lipid profile in patients with schizophrenia or related psychoses.
Topics: Adult; Anthropometry; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Clozapine; Female; Glucose Intolerance; Humans; Hyperprolactinemia; Insulin Resistance; Lipids; Male; Middle Aged; Olanzapine; Prolactin; Psychotic Disorders; Risperidone; Schizophrenia; Young Adult | 2011 |
[Effectiveness of antipsychotics in schizophrenia and related disorders. Results of a naturalistic study].
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Butyrophenones; Clozapine; Delayed-Action Preparations; Delusions; Dibenzothiazepines; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Olanzapine; Patient Dropouts; Prospective Studies; Psychotic Disorders; Quetiapine Fumarate; Retrospective Studies; Risperidone; Schizophrenia; Young Adult | 2011 |
Association study of brain-derived neurotrophic factor gene polymorphisms and body weight change in schizophrenic patients under long-term atypical antipsychotic treatment.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brain-Derived Neurotrophic Factor; Clozapine; Female; Genetic Association Studies; Haplotypes; Humans; Male; Middle Aged; Olanzapine; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Risperidone; Schizophrenia; Weight Gain; Young Adult | 2011 |
Association of serum levels of leptin, ghrelin, and adiponectin in schizophrenic patients and healthy controls.
Topics: Adiponectin; Adult; Antipsychotic Agents; Case-Control Studies; Clozapine; Female; Ghrelin; Humans; Leptin; Male; Metabolic Syndrome; Peptide Hormones; Risperidone; Schizophrenia; Taiwan | 2011 |
Clozapine and bladder control.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Female; Humans; Male; Nocturnal Enuresis; Risperidone | 2011 |
Onset of action of atypical and typical antipsychotics in the treatment of adolescent schizophrenic psychoses.
Topics: Adolescent; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Female; Haloperidol; Humans; Male; Medical Records; Olanzapine; Perphenazine; Piperazines; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Schizophrenia; Sulpiride; Thiazoles; Time Factors; Treatment Outcome | 2011 |
Nocturnal enuresis with antipsychotic medication.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Female; Humans; Male; Nocturnal Enuresis; Risperidone | 2012 |
Idiopathic granulomatous mastitis associated with risperidone-induced hyperprolactinemia.
Topics: Adult; Antipsychotic Agents; Biopsy; Clozapine; Drug Substitution; Female; Granulomatous Mastitis; Humans; Hyperprolactinemia; Mastectomy; Risperidone; Schizophrenia; Treatment Outcome | 2012 |
The impact of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) on prescribing practices: an analysis of data from a large midwestern state.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chi-Square Distribution; Clozapine; Dibenzothiazepines; Humans; Missouri; Olanzapine; Piperazines; Practice Patterns, Physicians'; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Thiazoles; Treatment Outcome | 2012 |
Second-generation antipsychotic medications and risk of pneumonia in schizophrenia.
Topics: Adult; Amisulpride; Antipsychotic Agents; Benzodiazepines; Case-Control Studies; Clozapine; Cohort Studies; Dibenzothiazepines; Dibenzothiepins; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Middle Aged; Olanzapine; Pneumonia; Quetiapine Fumarate; Risk Factors; Risperidone; Schizophrenia; Sulpiride; Taiwan | 2013 |
Ketamine-enhanced immobility in forced swim test: a possible animal model for the negative symptoms of schizophrenia.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Clozapine; Disease Models, Animal; Female; Haloperidol; Immobility Response, Tonic; Ketamine; Male; Motor Activity; Rats; Rats, Wistar; Reproducibility of Results; Risperidone; Schizophrenia; Swimming | 2012 |
Neuroleptics: bedwetting.
Topics: Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dibenzothiazepines; Humans; Nocturnal Enuresis; Olanzapine; Quetiapine Fumarate; Risperidone | 2012 |
Impact of switching or initiating antipsychotic treatment on body weight during a 6-month follow-up in a cohort of patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Body Mass Index; Body Weight; Clozapine; Cohort Studies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Olanzapine; Piperazines; Prospective Studies; Quinolones; Risperidone; Schizophrenia; Weight Loss | 2012 |
Two-dimensional gel electrophoresis revealed antipsychotic drugs induced protein expression modulations in C6 glioma cells.
Topics: Animals; Antipsychotic Agents; Cell Line, Tumor; Clozapine; Electrophoresis, Gel, Two-Dimensional; Frontal Lobe; Gene Expression; Glioma; Haloperidol; Rats; Risperidone; Time Factors | 2013 |
The role of ethnicity in treatment refractory schizophrenia.
Topics: Adult; Antipsychotic Agents; Canada; Clozapine; Female; Humans; Male; Middle Aged; Polypharmacy; Risperidone; Schizophrenia; Sex Factors; Treatment Failure | 2013 |
Selective acquired long QT syndrome (saLQTS) upon risperidone treatment.
Topics: Adult; Antipsychotic Agents; Clozapine; Electrocardiography; Female; Humans; Long QT Syndrome; Potassium Channels; Risperidone; Schizophrenia | 2012 |
Obsessive-compulsive symptoms in patients with schizophrenia: a naturalistic cross-sectional study comparing treatment with clozapine, olanzapine, risperidone, and no antipsychotics in 543 patients.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Case-Control Studies; Causality; Clozapine; Cross-Sectional Studies; Female; Humans; Male; Netherlands; Obsessive-Compulsive Disorder; Olanzapine; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Young Adult | 2012 |
[Follow-up of a 16-year-old adolescent with early-onset schizophrenia and catatonic symptoms].
Topics: Adolescent; Benzodiazepines; Carbamazepine; Clonazepam; Clozapine; Creatine Kinase; Diagnosis, Differential; Drug Resistance; Drug Substitution; Drug Therapy, Combination; Humans; Lorazepam; Male; Olanzapine; Patient Admission; Psychiatric Status Rating Scales; Psychometrics; Recurrence; Risperidone; Schizophrenia, Catatonic | 2013 |
Insulin secretion in patients receiving clozapine, olanzapine, quetiapine and risperidone.
Topics: Adult; Antipsychotic Agents; Area Under Curve; Benzodiazepines; Clozapine; Diabetes Mellitus, Type 2; Dibenzothiazepines; Female; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Olanzapine; Predictive Value of Tests; Quetiapine Fumarate; Regression Analysis; Risperidone | 2013 |
Study on human GPCR-inhibitor interactions by proteochemometric modeling.
Topics: Clozapine; Drug Design; Humans; Ligands; Models, Chemical; Receptors, G-Protein-Coupled; Reproducibility of Results; Risperidone; ROC Curve | 2013 |
Diabetes resolution following discontinuation of a second-generation antipsychotic.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Middle Aged; Olanzapine; Risperidone; Schizophrenia; Withholding Treatment | 2013 |
Second-generation antipsychotics cause a rapid switch to fat oxidation that is required for survival in C57BL/6J mice.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Astemizole; Behavior, Animal; Benzodiazepines; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Energy Metabolism; Epoxy Compounds; Fatty Acids; Hypoglycemic Agents; Male; Mice; Mice, Inbred C57BL; Motor Activity; Olanzapine; Oxygen Consumption; Piperazines; Quinolones; Receptors, Histamine H1; Respiration; Risperidone; Terfenadine; Time Factors | 2014 |
Effects of risperidone, clozapine and the 5-HT6 antagonist GSK-742457 on PCP-induced deficits in reversal learning in the two-lever operant task in male Sprague Dawley rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Extinction, Psychological; Learning Disabilities; Male; Phencyclidine; Quinolines; Rats; Rats, Sprague-Dawley; Reversal Learning; Risperidone; Serotonin Antagonists; Sulfones | 2013 |
LC-MS/MS of some atypical antipsychotics in human plasma, serum, oral fluid and haemolysed whole blood.
Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chromatography, Liquid; Clozapine; Dibenzothiazepines; Female; Forensic Toxicology; Hemolysis; Humans; Isoxazoles; Male; Olanzapine; Paliperidone Palmitate; Piperazines; Pyrimidines; Quetiapine Fumarate; Quinolones; Reproducibility of Results; Risperidone; Saliva; Serum; Sulpiride; Tandem Mass Spectrometry | 2013 |
Comparative safety of antipsychotics: another look at the risk of diabetes.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Case-Control Studies; Clozapine; Cohort Studies; Diabetes Mellitus, Type 2; Dibenzothiazepines; Female; Humans; Logistic Models; Male; Middle Aged; Olanzapine; Psychotic Disorders; Quetiapine Fumarate; Retrospective Studies; Risperidone; Time Factors; Young Adult | 2013 |
Stability of some atypical antipsychotics in human plasma, haemolysed whole blood, oral fluid, human serum and calf serum.
Topics: Amisulpride; Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Cattle; Chromatography, Liquid; Clozapine; Dibenzothiazepines; Drug Stability; Female; Forensic Toxicology; Hemolysis; Humans; Isoxazoles; Male; Olanzapine; Paliperidone Palmitate; Piperazines; Pyrimidines; Quetiapine Fumarate; Quinolones; Reproducibility of Results; Risperidone; Saliva; Serum; Sulpiride; Tandem Mass Spectrometry | 2013 |
Co-administration of 5-HT6 receptor antagonists with clozapine, risperidone, and a 5-HT2A receptor antagonist: effects on prepulse inhibition in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Data Interpretation, Statistical; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Haloperidol; Male; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reflex, Startle; Risperidone; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Sulfonamides; Thiophenes | 2014 |
Regulation of macrophage immune responses by antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Cell Differentiation; Clozapine; Humans; Lipopolysaccharides; Macrophages; Mice; Risperidone; Th1 Cells; Th2 Cells; U937 Cells | 2013 |
Investigation of molecular serum profiles associated with predisposition to antipsychotic-induced weight gain.
Topics: Adult; Antipsychotic Agents; Body Mass Index; Clozapine; Disease Susceptibility; ErbB Receptors; Female; Humans; Male; Middle Aged; Receptors, Interleukin-6; Receptors, Thyrotropin; Risperidone; Schizophrenia; Weight Gain; Young Adult | 2015 |
Long-term impacts of adolescent risperidone treatment on behavioral responsiveness to olanzapine and clozapine in adulthood.
Topics: Age Factors; Animals; Animals, Newborn; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Benzodiazepines; Clozapine; Dose-Response Relationship, Drug; Drug Interactions; Inhibition, Psychological; Male; Olanzapine; Rats; Rats, Sprague-Dawley; Reflex, Acoustic; Risperidone; Time; Time Factors | 2014 |
Clozapine-associated asterixis: case report.
Topics: Aged; Antipsychotic Agents; Clozapine; Drug Substitution; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Electroencephalography; Female; Humans; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2014 |
Hypochondriasis and obsessive-compulsive disorder in schizophrenic patients treated with clozapine vs other atypical antipsychotics.
Topics: Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Comorbidity; Female; Humans; Hypochondriasis; Male; Middle Aged; Obsessive-Compulsive Disorder; Olanzapine; Paliperidone Palmitate; Prevalence; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; Sulpiride | 2014 |
Pharmacoeconomics of depot antipsychotics for treating chronic schizophrenia in Sweden.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Cost of Illness; Cost-Benefit Analysis; Delayed-Action Preparations; Drug Costs; Female; Haloperidol; Health Care Costs; Hospitalization; Humans; Isoxazoles; Male; Middle Aged; Models, Econometric; Olanzapine; Paliperidone Palmitate; Palmitates; Quality-Adjusted Life Years; Risperidone; Schizophrenia; Sweden | 2014 |
Association between the brain-derived neurotrophic factor Val66Met polymorphism and therapeutic response to olanzapine in schizophrenia patients.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brain-Derived Neurotrophic Factor; Clozapine; Female; Genetic Association Studies; Genotype; Haloperidol; Humans; Male; Middle Aged; Olanzapine; Pharmacogenetics; Polymorphism, Single Nucleotide; Predictive Value of Tests; Risperidone; Schizophrenia; Treatment Outcome | 2014 |
The natural hallucinogen 5-MeO-DMT, component of Ayahuasca, disrupts cortical function in rats: reversal by antipsychotic drugs.
Topics: Amino Acids; Animals; Antipsychotic Agents; Banisteriopsis; Brain Waves; Bridged Bicyclo Compounds, Heterocyclic; Clozapine; Excitatory Amino Acid Agonists; Functional Neuroimaging; Hallucinogens; Haloperidol; Magnetic Resonance Imaging; Male; Methoxydimethyltryptamines; Prefrontal Cortex; Pyramidal Cells; Rats; Risperidone; Visual Cortex | 2014 |
Desipramine enhances the ability of risperidone to decrease alcohol intake in the Syrian golden hamster.
Topics: Alcohol Drinking; Animals; Brain; Clozapine; Desipramine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Female; Male; Mesocricetus; Receptors, Dopamine D2; Risperidone | 2014 |
Haloperidol treatment downregulates DCC expression in the ventral tegmental area.
Topics: Animals; Antipsychotic Agents; Clozapine; DCC Receptor; Dose-Response Relationship, Drug; Down-Regulation; Haloperidol; Male; Mice, Inbred C57BL; Netrin Receptors; Receptors, Cell Surface; Risperidone; Time Factors; Tumor Suppressor Proteins; Ventral Tegmental Area | 2014 |
A study of antioxidant activity in patients with schizophrenia taking atypical antipsychotics.
Topics: Adult; Antipsychotic Agents; Aryldialkylphosphatase; Cardiovascular Diseases; Clozapine; Female; Humans; Lipids; Male; Middle Aged; Risk Factors; Risperidone; Schizophrenia; Weight Gain | 2014 |
Effect of antipsychotic drugs on gene expression in the prefrontal cortex and nucleus accumbens in the spontaneously hypertensive rat (SHR).
Topics: Animals; Antipsychotic Agents; Clozapine; Disease Models, Animal; DNA Methylation; Gene Expression; Haloperidol; Male; Neurotransmitter Agents; Nucleus Accumbens; Prefrontal Cortex; Promoter Regions, Genetic; Rats, Inbred SHR; Risperidone; Schizophrenia | 2014 |
Cost-effectiveness of second-generation antipsychotics for the treatment of schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Cost-Benefit Analysis; Dibenzothiazepines; Drug Therapy, Combination; Female; Humans; Male; Markov Chains; Olanzapine; Piperazines; Quality-Adjusted Life Years; Quetiapine Fumarate; Risperidone; Schizophrenia; Thiazoles | 2014 |
P-glycoprotein activity in the blood-brain barrier is affected by virus-induced neuroinflammation and antipsychotic treatment.
Topics: Animals; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Clozapine; Disease Models, Animal; Herpes Simplex; Herpesvirus 1, Human; Male; Neuroimmunomodulation; Positron-Emission Tomography; Radiopharmaceuticals; Random Allocation; Rats, Wistar; Risperidone; Verapamil | 2014 |
Greater clinical and cognitive improvement with clozapine and risperidone associated with a thinner cortex at baseline in first-episode schizophrenia.
Topics: Adult; Antipsychotic Agents; Clozapine; Cognition Disorders; Disease Progression; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Memory; Organ Size; Prefrontal Cortex; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Speech Perception; Treatment Outcome; Young Adult | 2014 |
Adverse effects of antipsychotics on micro-vascular endothelial cells of the human blood-brain barrier.
Topics: Antipsychotic Agents; Apoptosis; Blood-Brain Barrier; Capillary Permeability; Caspase 3; Caspase 8; Caspase 9; Cell Survival; Cells, Cultured; Chlorpromazine; Clozapine; DNA Breaks; Endothelial Cells; Haloperidol; Humans; Microvessels; Oxidative Stress; Reactive Oxygen Species; Risperidone | 2014 |
Serum TNF-α, IL-10 and IL-2 in schizophrenic patients before and after treatment with risperidone and clozapine.
Topics: Adult; Antipsychotic Agents; Case-Control Studies; Clozapine; Female; Humans; Interleukin-10; Interleukin-2; Male; Risperidone; Schizophrenia; Serotonin Antagonists; Tumor Necrosis Factor-alpha; Young Adult | 2014 |
A systematic microdialysis study of dopamine transmission in the accumbens shell/core and prefrontal cortex after acute antipsychotics.
Topics: Administration, Intravenous; Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Dopamine; Haloperidol; Male; Microdialysis; Nucleus Accumbens; Prefrontal Cortex; Raclopride; Rats; Rats, Sprague-Dawley; Risperidone; Time Factors | 2015 |
Differential effects of clozapine, metoclopramide, haloperidol and risperidone on acquisition and performance of operant responding in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Conditioning, Operant; Dopamine D2 Receptor Antagonists; Haloperidol; Male; Metoclopramide; Prefrontal Cortex; Rats; Rats, Wistar; Risperidone | 2015 |
Formulation and characterization of clozapine and risperidone co-entrapped spray-dried PLGA nanoparticles.
Topics: Chemistry, Pharmaceutical; Clozapine; Drug Carriers; Drug Combinations; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Risperidone; X-Ray Diffraction | 2016 |
Comparative analysis of the treatment of chronic antipsychotic drugs on epileptic susceptibility in genetically epilepsy-prone rats.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Disease Models, Animal; Epilepsy; Haloperidol; Mental Disorders; Olanzapine; Quetiapine Fumarate; Rats; Risperidone; Seizures | 2015 |
Regulation of neutrophil phagocytosis of Escherichia coli by antipsychotic drugs.
Topics: Antipsychotic Agents; Blotting, Western; Clozapine; Escherichia coli; Haloperidol; HL-60 Cells; Humans; Interleukin-8; Macrophage-1 Antigen; Neutrophils; Peroxidase; Phagocytosis; Risperidone | 2014 |
Clozapine influences cytoskeleton structure and calcium homeostasis in rat cerebral cortex and has a different proteomic profile than risperidone.
Topics: Animals; Antipsychotic Agents; Calcium; Cerebral Cortex; Clozapine; Cytoskeleton; Homeostasis; Male; Proteomics; Rats; Rats, Wistar; Risperidone | 2015 |
Cognitive differences in schizophrenia on long-term treatments with clozapine, risperidone and typical antipsychotics.
Topics: Adult; Aged; Antipsychotic Agents; Case-Control Studies; Clozapine; Cognition Disorders; Cross-Sectional Studies; Female; Humans; Language; Male; Memory; Middle Aged; Neuropsychological Tests; Risperidone; Schizophrenia; Schizophrenic Psychology | 2015 |
Clozapine and olanzapine inhibit proton currents in BV2 microglial cells.
Topics: Animals; Anti-Inflammatory Agents; Antipsychotic Agents; Benzodiazepines; Cell Line; Clozapine; Mice; Microglia; Olanzapine; Protons; Risperidone | 2015 |
Vitamin D deficiency exacerbates atypical antipsychotic-induced metabolic side effects in rats: involvement of the INSIG/SREBP pathway.
Topics: Animals; Antipsychotic Agents; Body Weight; Clozapine; Disease Models, Animal; Eating; Glucose Intolerance; Glucose Tolerance Test; Insulin Resistance; Intra-Abdominal Fat; Male; Random Allocation; Rats, Sprague-Dawley; Risperidone; Vitamin D Deficiency | 2015 |
Inflammation and psychotropic drugs: the relationship between C-reactive protein and antipsychotic drug levels.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Biomarkers; C-Reactive Protein; Clozapine; Female; Humans; Inflammation; Male; Psychotic Disorders; Psychotropic Drugs; Quetiapine Fumarate; Risperidone; ROC Curve | 2016 |
Association studies of genomic variants with treatment response to risperidone, clozapine, quetiapine and chlorpromazine in the Chinese Han population.
Topics: Adolescent; Adult; Antipsychotic Agents; Asian People; Chi-Square Distribution; China; Chlorpromazine; Clozapine; Cross-Sectional Studies; Female; Genetic Association Studies; Haplotypes; Humans; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Pharmacogenomic Testing; Pharmacogenomic Variants; Phenotype; Polymorphism, Single Nucleotide; Predictive Value of Tests; Quetiapine Fumarate; Reelin Protein; Risk Factors; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; Young Adult | 2016 |
Low expression of Gria1 and Grin1 glutamate receptors in the nucleus accumbens of Spontaneously Hypertensive Rats (SHR).
Topics: Animals; Antipsychotic Agents; Clozapine; Disease Models, Animal; Gene Expression; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Inbred SHR; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; Risperidone; Schizophrenia | 2015 |
Association of orexin receptor polymorphisms with antipsychotic-induced weight gain.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Female; Genetic Association Studies; Humans; Male; Middle Aged; Olanzapine; Orexin Receptors; Polymorphism, Single Nucleotide; Risperidone; Schizophrenia; United States; Weight Gain; White People; Young Adult | 2016 |
A potential mechanism underlying atypical antipsychotics-induced lipid disturbances.
Topics: Animals; Antipsychotic Agents; Blotting, Western; Cholesterol; Clozapine; Corticosterone; Disease Models, Animal; Fatty Acids, Nonesterified; Insulin; Lipid Metabolism; Lipogenesis; Liver; Male; Polymerase Chain Reaction; Progesterone; Rats; Rats, Sprague-Dawley; Risperidone; Signal Transduction; Triglycerides | 2015 |
Stathmin reduction and cytoskeleton rearrangement in rat nucleus accumbens in response to clozapine and risperidone treatment - Comparative proteomic study.
Topics: Animals; Antipsychotic Agents; Clozapine; Cyclin-Dependent Kinase 5; Cytoskeleton; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Gene Expression Regulation; Heat-Shock Proteins; Male; Nerve Tissue Proteins; Nucleus Accumbens; Protein Processing, Post-Translational; Proteomics; Rats; Rats, Wistar; Risperidone; Stathmin | 2016 |
Cost-effectiveness Analysis of Aripiprazole Once-Monthly for the Treatment of Schizophrenia in the UK.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chronic Disease; Clozapine; Computer Simulation; Cost-Benefit Analysis; Delayed-Action Preparations; Drug Administration Schedule; Humans; Injections, Intramuscular; Markov Chains; Models, Economic; Olanzapine; Paliperidone Palmitate; Quetiapine Fumarate; Risperidone; Schizophrenia; Schizophrenic Psychology; State Medicine; United Kingdom | 2015 |
In-depth neuropharmacokinetic analysis of antipsychotics based on a novel approach to estimate unbound target-site concentration in CNS regions: link to spatial receptor occupancy.
Topics: Animals; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B; Benzodiazepines; Blood-Brain Barrier; Brain; Cerebrospinal Fluid; Clozapine; Haloperidol; Male; Neuropharmacology; Olanzapine; Paliperidone Palmitate; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Risperidone | 2016 |
Effects of prolonged antipsychotic administration on neuregulin-1/ErbB signaling in rat prefrontal cortex and myocardium: implications for the therapeutic action and cardiac adverse effect.
Topics: Animals; Antipsychotic Agents; Cardiovascular Diseases; Clozapine; Comorbidity; Genetic Predisposition to Disease; Haloperidol; Injections, Intraperitoneal; Male; Myocardium; Neuregulin-1; Phosphorylation; Prefrontal Cortex; Rats, Sprague-Dawley; Receptor, ErbB-2; Receptor, ErbB-4; Risk; Risperidone; Schizophrenia; Signal Transduction; Time Factors | 2016 |
[Plasma levels of antipsychotics and the severity of side-effects in the treatment of schizophrenia exacerbation].
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Blood Glucose; Clozapine; Depression; Drug Therapy, Combination; Female; Haloperidol; Humans; Hyperprolactinemia; Male; Middle Aged; Olanzapine; Prolactin; Risperidone; Schizophrenia; Schizophrenic Psychology; Young Adult | 2015 |
Association between SCAP and SREBF1 gene polymorphisms and metabolic syndrome in schizophrenia patients treated with atypical antipsychotics.
Topics: Adult; Alleles; Antipsychotic Agents; Benzodiazepines; Case-Control Studies; China; Clozapine; Female; Genotype; Humans; Intracellular Signaling Peptides and Proteins; Linkage Disequilibrium; Logistic Models; Male; Membrane Proteins; Metabolic Syndrome; Middle Aged; Olanzapine; Polymorphism, Single Nucleotide; Risperidone; Schizophrenia; Sterol Regulatory Element Binding Protein 1 | 2016 |
Fever, confusion, acute kidney injury: is this atypical neuroleptic malignant syndrome following polypharmacy with clozapine and risperidone?
Topics: Acute Kidney Injury; Aged; Antipsychotic Agents; Clozapine; Confusion; Fever; Humans; Male; Neuroleptic Malignant Syndrome; Polypharmacy; Risperidone; Schizophrenia | 2016 |
Clozapine and olanzapine are better antioxidants than haloperidol, quetiapine, risperidone and ziprasidone in in vitro models.
Topics: Antioxidants; Antipsychotic Agents; Benzodiazepines; Biphenyl Compounds; Clozapine; Free Radical Scavengers; Haloperidol; Humans; Models, Biological; Neutrophil Activation; Neutrophils; Olanzapine; Picrates; Piperazines; Quetiapine Fumarate; Reactive Oxygen Species; Risperidone; Tetradecanoylphorbol Acetate; Thiazoles | 2016 |
Gene-expression analysis of clozapine treatment in whole blood of patients with psychosis.
Topics: Adult; Antipsychotic Agents; Clozapine; Female; Gene Expression; Gene Expression Profiling; Humans; Male; Middle Aged; Psychotic Disorders; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia | 2016 |
Comparative effectiveness and safety of antipsychotic drugs in schizophrenia treatment: a real-world observational study.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Female; Humans; Male; Middle Aged; Olanzapine; Proportional Hazards Models; Quebec; Quetiapine Fumarate; Retrospective Studies; Risperidone; Schizophrenia; Treatment Outcome | 2016 |
Hyperprolactinemia, prolactin-related side effects and quality of life in Chinese psychiatric patients.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Case-Control Studies; China; Clozapine; Female; Humans; Hyperprolactinemia; Male; Mental Disorders; Quality of Life; Risperidone; Sexual Dysfunction, Physiological; Young Adult | 2016 |
Level of serum thioredoxin and correlation with neurocognitive functions in patients with schizophrenia using clozapine and other atypical antipsychotics.
Topics: Adult; Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Olanzapine; Psychotic Disorders; Risperidone; Schizophrenia; Sulpiride; Thioredoxins; Young Adult | 2017 |
Sedative effect of Clozapine is a function of 5-HT
Topics: Animals; Antipsychotic Agents; Caffeine; Central Nervous System Stimulants; Clozapine; Dose-Response Relationship, Drug; Environment; Exploratory Behavior; Genotype; Haloperidol; Inhibition, Psychological; Mice; Mice, Knockout; Receptor, Serotonin, 5-HT2A; Risperidone; Serotonin Antagonists | 2017 |
Effects of antipsychotics on intestinal motility in zebrafish larvae.
Topics: Animals; Antipsychotic Agents; Atropine; Clozapine; Drug Evaluation, Preclinical; Gastrointestinal Motility; Gastrointestinal Tract; Haloperidol; Larva; Muscarinic Antagonists; Risperidone; Zebrafish | 2017 |
Clozapine usage increases the incidence of pneumonia compared with risperidone and the general population: a retrospective comparison of clozapine, risperidone, and the general population in a single hospital over 25 months.
Topics: Antipsychotic Agents; Case-Control Studies; Clozapine; Female; Humans; Incidence; Male; Middle Aged; Minnesota; Pneumonia; Retrospective Studies; Risperidone; Schizophrenia | 2017 |
Sex Differences in Psychiatric Hospitalizations of Individuals With Psychotic Disorders.
Topics: Adult; Aged; Antipsychotic Agents; Clozapine; Commitment of Mentally Ill; Female; Hospitalization; Hospitals, Psychiatric; Humans; Length of Stay; Male; Middle Aged; Psychotic Disorders; Retrospective Studies; Risperidone; Sex Factors; Young Adult | 2017 |
The Differential Binding of Antipsychotic Drugs to the ABC Transporter P-Glycoprotein Predicts Cannabinoid-Antipsychotic Drug Interactions.
Topics: Animals; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Clozapine; Dose-Response Relationship, Drug; Dronabinol; Gene Expression Regulation; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Binding; Proto-Oncogene Proteins c-fos; Raclopride; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Reflex, Startle; Risperidone; Time Factors; Tritium | 2017 |
Comparative study of clozapine versus risperidone in treatment-naive, first-episode schizophrenia: A pilot study.
Topics: Adolescent; Adult; Antipsychotic Agents; Clozapine; Female; Humans; Male; Pilot Projects; Quality of Life; Risperidone; Schizophrenia; Treatment Outcome | 2016 |
The role of oxidative stress in antipsychotics induced ovarian toxicity.
Topics: Animals; Antipsychotic Agents; Caspases; Cell Survival; Cells, Cultured; Chlorpromazine; Clozapine; Female; Glutathione; Haloperidol; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Risperidone; Theca Cells | 2017 |
Clozapine, chlorpromazine and risperidone dose-dependently reduce emotional hyperthermia, a biological marker of salience.
Topics: Animals; Arousal; Chlorpromazine; Clozapine; Dose-Response Relationship, Drug; Emotions; Fever; Male; Rats; Rats, Sprague-Dawley; Risperidone; Thermogenesis; Vasoconstriction | 2017 |
Effects of age and gender on the serum levels of clozapine, olanzapine, risperidone, and quetiapine.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Clozapine; Female; Humans; Male; Middle Aged; Norway; Olanzapine; Quetiapine Fumarate; Risperidone; Sex Factors; Young Adult | 2017 |
Overexpression of Insig-2 inhibits atypical antipsychotic-induced adipogenic differentiation and lipid biosynthesis in adipose-derived stem cells.
Topics: Adipogenesis; Animals; Antipsychotic Agents; Cell Differentiation; Cells, Cultured; Clozapine; Cytosol; Fatty Acids; Intracellular Signaling Peptides and Proteins; Lipid Metabolism; Mesenchymal Stem Cells; Olanzapine; Rats, Inbred Lew; Risperidone; Sterol Regulatory Element Binding Proteins | 2017 |
Periodic catatonia with long-term treatment: a case report.
Topics: Antipsychotic Agents; Catatonia; Clozapine; Drug Therapy, Combination; Female; Haloperidol; Humans; Loxapine; Middle Aged; Risperidone; Schizophrenia | 2017 |
Clozapine Reduces All-Cause Mortality.
Topics: Antipsychotic Agents; Clozapine; Humans; Risperidone; Schizophrenia | 2017 |
An Unexpected Circumstance: Acute Dystonic Reaction in the Setting of Clozapine Administration.
Topics: Acute Disease; Adult; Antipsychotic Agents; Clozapine; Drug Interactions; Dystonia; Humans; Male; Psychotic Disorders; Risperidone | 2019 |
Cortical high gamma network oscillations and connectivity: a translational index for antipsychotics to normalize aberrant neurophysiological activity.
Topics: Amphetamine; Animals; Antipsychotic Agents; Benzodiazepines; Brain Waves; Central Nervous System Stimulants; Cerebral Cortex; Clozapine; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Male; Nerve Net; Olanzapine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Risperidone | 2017 |
Comparative effects of aripiprazole and selected antipsychotic drugs on lipid peroxidation in plasma.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Blood; Clozapine; Female; Humans; Lipid Peroxidation; Male; Olanzapine; Piperazines; Quetiapine Fumarate; Risperidone; Thiazoles; Thiobarbituric Acid Reactive Substances; Young Adult | 2018 |
Predictors of remission during acute treatment of first-episode schizophrenia patients involuntarily hospitalized and treated with algorithm-based pharmacotherapy: Secondary analysis of an observational study.
Topics: Administration, Oral; Adult; Algorithms; Antipsychotic Agents; Clozapine; Commitment of Mentally Ill; Drug Therapy, Combination; Female; Haloperidol; Humans; Injections, Intramuscular; Male; Methotrimeprazine; Olanzapine; Psychotic Disorders; Quetiapine Fumarate; Retrospective Studies; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Failure; Treatment Outcome | 2019 |
Alterations in oxidative stress markers and its correlation with clinical findings in schizophrenic patients consuming perphenazine, clozapine and risperidone.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Biomarkers; Clozapine; Humans; Middle Aged; Oxidative Stress; Perphenazine; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Young Adult | 2018 |
Positive response to clozapine augmentation in a patient with obsessive-compulsive disorder complicated by a tardive movement disorder.
Topics: Adult; Antipsychotic Agents; Clozapine; Female; Humans; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Risperidone; Tardive Dyskinesia; Time Factors; Treatment Outcome | 2018 |
Mitochondrial DNA copy number is associated with psychosis severity and anti-psychotic treatment.
Topics: Adult; Antipsychotic Agents; Clozapine; DNA Copy Number Variations; DNA, Mitochondrial; Female; Humans; Male; Middle Aged; Models, Genetic; Neurons; Psychotic Disorders; Risperidone; Severity of Illness Index | 2018 |
Electroencephalogram Modifications Associated With Atypical Strict Antipsychotic Monotherapies.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Cerebral Cortex; Clozapine; Depressive Disorder, Major; Electroencephalography; Female; Humans; Male; Mental Disorders; Middle Aged; Olanzapine; Psychotic Disorders; Quetiapine Fumarate; Risperidone; Schizophrenia; Young Adult | 2018 |
Analysis of smoking behavior on the pharmacokinetics of antidepressants and antipsychotics: evidence for the role of alternative pathways apart from CYP1A2.
Topics: Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Clozapine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Desvenlafaxine Succinate; Doxepin; Drug Monitoring; Female; Glucuronosyltransferase; Humans; Male; Middle Aged; Mirtazapine; Nortriptyline; Paliperidone Palmitate; Quetiapine Fumarate; Retrospective Studies; Risperidone; Smoking; Venlafaxine Hydrochloride | 2019 |
Physiologically Based Modeling Approach to Predict Dopamine D2 Receptor Occupancy of Antipsychotics in Brain: Translation From Rat to Human.
Topics: Animals; Antipsychotic Agents; Brain; Clozapine; Dopamine D2 Receptor Antagonists; Female; Humans; Kinetics; Male; Models, Biological; Paliperidone Palmitate; Rats; Receptors, Dopamine D2; Risperidone; Translational Research, Biomedical | 2019 |
Prenatal treatment with methylazoxymethanol acetate as a neurodevelopmental disruption model of schizophrenia in mice.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Clozapine; Disease Models, Animal; Female; Haloperidol; Hippocampus; Methylazoxymethanol Acetate; Mice; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Prepulse Inhibition; Risperidone; Schizophrenia | 2019 |
Psychotropic-Induced Priapism in a Treatment-Refractory Patient: A Case Report.
Topics: Adult; Antipsychotic Agents; Clozapine; Humans; Male; Priapism; Quetiapine Fumarate; Risperidone | 2021 |
Persistence of Antipsychotic Use After Clozapine Discontinuation: A Real-World Study Across Antipsychotics.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Clozapine; Drug Substitution; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Medication Adherence; Middle Aged; Netherlands; Olanzapine; Registries; Retrospective Studies; Risperidone; Schizophrenia; Treatment Outcome | 2020 |
[Antioxidant status in patients with paranoid schizophrenia and Alzheimer disease].
Topics: Alzheimer Disease; Antioxidants; Antipsychotic Agents; Clozapine; Humans; Risperidone; Schizophrenia, Paranoid | 2020 |
Identification and Quantification of Antipsychotics in Blood Samples by LC-MS-MS: Case Reports and Data from Three Years of Routine Analysis.
Topics: Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chromatography, Liquid; Clozapine; Dibenzothiazepines; Female; Forensic Toxicology; Humans; Male; Olanzapine; Paliperidone Palmitate; Piperazines; Quetiapine Fumarate; Retrospective Studies; Risperidone; Schizophrenia; Substance Abuse Detection; Suicide; Sulpiride; Tandem Mass Spectrometry; Thiazoles | 2020 |
Characteristics of White Matter Structural Networks in Chronic Schizophrenia Treated With Clozapine or Risperidone and Those Never Treated.
Topics: Adult; Antipsychotic Agents; Chronic Disease; Clozapine; Cognitive Dysfunction; Diffusion Tensor Imaging; Female; Humans; Male; Middle Aged; Nerve Net; Risperidone; Schizophrenia; Treatment Outcome; White Matter | 2020 |
Differential effects of different antipsychotic drugs on cognitive function in patients with chronic schizophrenia.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Case-Control Studies; Chronic Disease; Clozapine; Cognition; Cross-Sectional Studies; Female; Humans; Language; Male; Memory; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Young Adult | 2020 |
The side effect profile of Clozapine in real world data of three large mental health hospitals.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Databases, Factual; Female; Hospitals, Psychiatric; Humans; Infant; Male; Middle Aged; Olanzapine; Piperazines; Risperidone; Schizophrenia; Thiazoles; Weight Gain | 2020 |
The effect of prohibiting outside food during COVID-19 pandemic on the body weight of schizophrenic patients taking olanzapine or clozapine: a retrospective self-controlled study.
Topics: Antipsychotic Agents; Benzodiazepines; Body Weight; China; Clozapine; COVID-19; Humans; Olanzapine; Pandemics; Retrospective Studies; Risperidone; SARS-CoV-2; Schizophrenia | 2021 |
Clozapine affects the pharmacokinetics of risperidone and inhibits its metabolism and P-glycoprotein-mediated transport in vivo and in vitro: A safety attention to antipsychotic polypharmacy with clozapine and risperidone.
Topics: Animals; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Brain; Caco-2 Cells; Clozapine; Drug Interactions; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Microsomes, Liver; Rats, Sprague-Dawley; Risk Assessment; Risperidone; Tissue Distribution | 2021 |
Proteome Analysis of PC12 Cells Reveals Alterations in Translation Regulation and Actin Signaling Induced by Clozapine.
Topics: Actin Cytoskeleton; Acute-Phase Reaction; Animals; Antipsychotic Agents; Ciliary Neurotrophic Factor; Clozapine; Haloperidol; PC12 Cells; Protein Biosynthesis; Proteome; Rats; rho GTP-Binding Proteins; Risperidone; Signal Transduction | 2021 |
Infection is associated with elevated serum concentrations of antipsychotic drugs.
Topics: Antipsychotic Agents; Aripiprazole; Clozapine; Humans; Quetiapine Fumarate; Respiratory Tract Infections; Risperidone | 2021 |
Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood-brain barrier.
Topics: Antipsychotic Agents; Biological Transport; Blood-Brain Barrier; Brain; Clozapine; Risperidone | 2021 |
Characteristics of the corpus callosum in chronic schizophrenia treated with clozapine or risperidone and those never-treated.
Topics: Anisotropy; Clozapine; Corpus Callosum; Cross-Sectional Studies; Diffusion Tensor Imaging; Humans; Risperidone; Schizophrenia | 2021 |
Effects of clozapine and risperidone antipsychotic drugs on the expression of CACNA1C and behavioral changes in rat 'Ketamine model of schizophrenia.
Topics: Animals; Antipsychotic Agents; Calcium Channels, L-Type; Clozapine; Cognition; Excitatory Amino Acid Antagonists; Hippocampus; Ketamine; Male; Maze Learning; Rats; Rats, Wistar; Risperidone; Schizophrenia; Social Behavior | 2022 |
Atypical, but Not Typical, Antipsychotic Drugs Reduce Hypersynchronized Prefrontal-Hippocampal Circuits during Psychosis-Like States in Mice: Contribution of 5-HT2A and 5-HT1A Receptors.
Topics: Animals; Antipsychotic Agents; Clozapine; Haloperidol; Hippocampus; Mice; Phencyclidine; Prefrontal Cortex; Psychotic Disorders; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Risperidone; Serotonin Antagonists | 2022 |
Precision psychiatry: The complexity of personalizing antipsychotic dosing.
Topics: Antipsychotic Agents; Benzodiazepines; Carbamazepine; Clozapine; Female; Humans; Male; Paliperidone Palmitate; Psychiatry; Risperidone | 2022 |
Phenotypical Screening on Neuronal Plasticity in Hippocampal-Prefrontal Cortex Connectivity Reveals an Antipsychotic with a Novel Profile.
Topics: Animals; Antipsychotic Agents; Clozapine; Hippocampus; Neuronal Plasticity; Prefrontal Cortex; Rats; Rats, Wistar; Risperidone | 2022 |
Sodium nitroprusside enhances the antipsychotic-like effect of olanzapine but not clozapine in the conditioned avoidance response test in rats.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; Clozapine; Nitroprusside; Olanzapine; Rats; Rats, Sprague-Dawley; Risperidone | 2022 |
Characteristics of adverse reactions among antipsychotic drugs using the Korean Adverse Event Reporting System database from 2010 to 2019.
Topics: Adolescent; Adult; Aged; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Child; Clozapine; Drug-Related Side Effects and Adverse Reactions; Haloperidol; Humans; Olanzapine; Paliperidone Palmitate; Quetiapine Fumarate; Retrospective Studies; Risperidone; Schizophrenia | 2022 |
Top-Up Clozapine for Risperidone LAI-Related Acute Dystonia and TR Bipolar in an Adolescent with ID-
Topics: Adolescent; Antipsychotic Agents; Clozapine; Dystonia; Dystonic Disorders; Humans; Intellectual Disability; Risperidone | 2022 |
Letter to the Editor: Rethinking The Cost Of Antipsychotic Treatment: The Average Cost Of The Drugs Used In Turkey In 2020.
Topics: Adenosine Monophosphate; Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chlorpromazine; Clopenthixol; Clozapine; Flupenthixol; Fluphenazine; Haloperidol; Humans; Olanzapine; Paliperidone Palmitate; Pharmaceutical Preparations; Pimozide; Quetiapine Fumarate; Risperidone; Sulpiride; Trifluoperazine | 2022 |
Long-term treatment of antipsychotics and combined therapy with other psychotropic medications inducing weight gain in patients with non-affective psychotic disorder: Evidence from GROUP, a longitudinal study.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Humans; Longitudinal Studies; Olanzapine; Psychotic Disorders; Psychotropic Drugs; Quetiapine Fumarate; Risperidone; Weight Gain | 2022 |
The impact of adjunctive aripiprazole on QT interval: A 12-week open label study in patients on olanzapine, clozapine or risperidone.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Humans; Olanzapine; Piperazines; Prospective Studies; Risperidone | 2023 |
[Antipsychotics].
Topics: Antipsychotic Agents; Clozapine; Hallucinations; Humans; Risperidone; Schizophrenia | 2023 |
Oculogyric crisis symptoms related to risperidone treatment: a case report.
Topics: Adult; Antipsychotic Agents; Clozapine; Dystonic Disorders; Female; Humans; Quality of Life; Risperidone; Young Adult | 2023 |