Page last updated: 2024-08-16

risperidone and chlorpromazine

risperidone has been researched along with chlorpromazine in 109 studies

Research

Studies (109)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	13 (11.93)	18.2507
2000's	57 (52.29)	29.6817
2010's	34 (31.19)	24.3611
2020's	5 (4.59)	2.80

Authors

Authors	Studies
Baldy, WJ; Barrett, DL; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Kukla, MJ; Martin, GE; Mathiasen, JR; Scott, MK	1
Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A	1
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR	1
Egan, CT; Herrick-Davis, K; Teitler, M	1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L	1
Topliss, JG; Yoshida, F	1
Grinde, E; Herrick-Davis, K; Teitler, M	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Boulton, DW; DeVane, CL; Liston, HL; Markowitz, JS	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M	1
Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S	1
Glennon, RA	1
Keserü, GM	1
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA	1
Herrick-Davis, K; Purohit, A; Smith, C; Teitler, M	1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Coolen, HK; Glennon, JC; Kruse, CG; Lange, JH; Reinders, JH; Tolboom, JT	1
Farasati, NA; Huang, Y; Randhawa, P	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Caron, G; Ermondi, G; Visentin, S	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F	1
Sen, S; Sinha, N	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Dalvie, D; Loi, CM; Smith, DA	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Freeman, BB; Rankovic, Z; Yang, L	1
Aghajanian, GK; Gellman, RL	1
Auchus, AP; Freeman, A; Green, RC	1
DeVane, CL	1
Conway, PC; Corbett, R; Dunn, RW; Hartman, H; Helsley, GC; Kerman, LL; Strupczewski, JT; Woods, AT	1
Matsubara, R	1
Finlayson, A; Johnstone, EC; Mercer, G; Murray, C; Owens, DG	1
Ervine, CM; Hughes, AM; Lynch, P; Rhodes, J; Yates, RA	1
McCallum, SE; Porter, JH; Vann, RE; Varvel, SA	1
Kameda, K; Koyama, T; Kusumi, I; Suzuki, K; Takahashi, Y	1
Hori, M; Hori, T; Kawanishi, Y; Shiraishi, H; Suzuki, T; Tachikawa, H	1
Nomikos, GG; Rodriguez, DE; Shirazi-Southall, S	1
Hägg, S; Hedenmalm, K; Mortimer, O; Spigset, O; Ståhl, M	1
Goudie, AJ; Smith, JA	1
Kamijo, Y; Kurihara, K; Nagai, T; Ohwada, T; Soma, K	1
Kalkman, HO; Loetscher, E	1
Dhawan, BN; Kumar, R; Palit, G	1
Woods, SW	1
Morishita, S	1
Burnet, PW; Harrison, PJ; Hutchinson, LJ; Law, AJ	1
Matsuoka, N; Mutoh, S; Shirakawa, K; Tada, M	1
Barrett, SL; Bell, R; King, DJ; Watson, D	1
Girimaji, SC; Jairam, R; Seshadri, SP; Srinath, S	1
Lawrie, S; McIntosh, A; Nadeem, Z	2
Lawrie, S; McIntosh, A	1
Adams, AS; Kanavos, P; Park, S; Ross-Degnan, D; Sabin, J; Soumerai, SB	1
Liu, W; Mou, XD; Shi, JB; Sun, J; Yao, ZJ; Zhang, XR; Zhang, ZJ	1
Balit, CR; Isbister, GK; Kilham, HA	1
Mahadik, SP; Pillai, A; Terry, AV	1
Mahadik, SP; Parikh, V; Pillai, A; Terry, AV	1
Bastianetto, S; Danik, M; Mennicken, F; Quirion, R; Williams, S	1
Chen, CD; Kao, WT; Lung, FW; Tung, YP; Wang, CS	1
DeVane, CL; Donovan, JL; Markowitz, JS; Wang, JS; Zhu, HJ	1
Boshoven, W; Duncan, E; Dunlop, BW; Hamer, RM; Phillips, LS; Woolson, SL	1
Dierks, T; Irisawa, S; Isotani, T; Kikuchi, M; Kinoshita, T; Koenig, T; Okugawa, G; Strik, W; Yagyu, T; Yamada, K; Yoshimura, M	1
Eberhard, J; Holstad, M; Levander, S; Lindström, E	1
Bishnoi, M; Chopra, K; Kulkarni, SK; Kumar, A	1
Jin, GX; Tong, Y; Wang, XP; Wang, XY; Yao, SM; Zhang, ZJ	1
Carlsson, A; Stening, G; Timdahl, K	1
Cooper, T; Usubiaga, H; Winsberg, B	1
Athey, R; Forlano, R; Singh, D	1
Buyukoglan, H; Kaya, MG; Ulusoy, HB; Yagmur, F	1
Jayaram, MB; Rattehalli, RD; Sivaraman, P	1
Bogdan, F; Bogdan, M; Popescu, F	1
Diefenderfer, LA; Iuppa, CA	1
Elmorsy, E; Elsheikha, HM; Elzalabany, LM; Smith, PA	1
De Luca, MA; Di Chiara, G; Perra, V; Serra, GP; Tanda, G; Valentini, V	1
Babigumira, JB; Lubinga, SJ; Mutamba, BB; Nganizi, A	1
He, L; Huang, H; Li, M; Minica, C; Qin, S; Shen, L; Shi, Y; Wang, G; Wu, X; Xing, Q; Xu, Q; Yi, Z	1
Baytunca, MB; Erermis, S; Kose, S; Ozbaran, B	1
Lee, SY; Lee, TL; Shyu, YC; Wang, LJ; Yang, CJ; Yang, KC; Yuan, SS	1
Bo, L; Saha, KB; Sampson, S; Xia, J; Zaman, RU; Zhao, S	1
Ino, H; Ishige, M; Iyo, M; Kanahara, N; Kimura, H; Komatsu, H; Komatsu, N; Muneoka, K; Sasaki, T; Shimizu, E; Suzuki, T; Watanabe, H; Yamanaka, H; Yoshimura, K	1
Bielecka-Wajdman, AM; Nowacka, M; Obuchowicz, E; Paul-Samojedny, M	1
Arasappa, R; Chand, PK; Kulkarni, K; Muralidharan, K; Murthy, P; Philip, M; Prasad M, K; Zutshi, A	1
Deng, H; Xu, J	1
Aggour, AM; Al-Ghafari, A; Amer, S; Elmorsy, E; Khan, R	1
Blessing, EM; Blessing, WW; Mohammed, M; Ootsuka, Y	1
Hirai, T; Kose, E; Seki, T; Yasuno, N	1
Basu, B; John Jayakumar, JAK; Panicker, MM	1
Aguglia, E; Amore, M; Bellomo, A; Bertolino, A; Cascino, G; Collantoni, E; Corrivetti, G; Cuomo, A; D'Ambrosio, E; Dell'Osso, L; Frascarelli, M; Galderisi, S; Giordano, GM; Giuliani, L; Maj, M; Marchesi, C; Monteleone, AM; Monteleone, P; Montemagni, C; Oldani, L; Pinna, F; Pompili, M; Rocca, P; Roncone, R; Rossi, A; Rossi, R; Siracusano, A; Vita, A; Zeppegno, P	1
Sood, S	1
Osman, E; Yıldız, M	1

Reviews

14 review(s) available for risperidone and chlorpromazine

Article	Year
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7). Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14 Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists	2003
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Practical approaches to evaluating and optimizing brain exposure in early drug discovery. European journal of medicinal chemistry, 2019, Nov-15, Volume: 182 Topics: Animals; Blood-Brain Barrier; Central Nervous System; Central Nervous System Agents; Drug Delivery Systems; Drug Discovery; Humans; Molecular Structure; Structure-Activity Relationship	2019
Brief comparison of the pharmacokinetics and pharmacodynamics of the traditional and newer antipsychotic drugs. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1995, Feb-01, Volume: 52, Issue:3 Suppl 1 Topics: Antipsychotic Agents; Chlorpromazine; Clozapine; Haloperidol; Humans; Isoxazoles; Piperidines; Risperidone; Time Factors	1995
Chlorpromazine equivalent doses for the newer atypical antipsychotics. The Journal of clinical psychiatry, 2003, Volume: 64, Issue:6 Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chlorpromazine; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Administration Schedule; Haloperidol; Humans; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Therapeutic Equivalency; Thiazoles	2003
[Late schizophrenia]. Ryoikibetsu shokogun shirizu, 2003, Issue:38 Topics: Adult; Age of Onset; Aged; Antipsychotic Agents; Chlorpromazine; Clozapine; Diagnostic and Statistical Manual of Mental Disorders; Electroconvulsive Therapy; Haloperidol; Humans; Middle Aged; Reference Standards; Risk Factors; Risperidone; Schizophrenia; Schizophrenic Psychology	2003
Schizophrenia. Clinical evidence, 2003, Issue:10 Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Cognitive Behavioral Therapy; Dibenzothiepins; Haloperidol; Humans; Olanzapine; Patient Compliance; Perazine; Pimozide; Risperidone; Schizophrenia; Sulpiride	2003
Schizophrenia. Clinical evidence, 2004, Issue:12 Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Haloperidol; Humans; Olanzapine; Patient Compliance; Perazine; Pimozide; Risperidone; Schizophrenia; Sulpiride	2004
Antipsychotic poisoning in young children: a systematic review. Drug safety, 2005, Volume: 28, Issue:11 Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Child; Child, Preschool; Chlorpromazine; Clozapine; Dibenzothiazepines; Haloperidol; Humans; Infant; Infant, Newborn; Olanzapine; Pimozide; Piperazines; Poisoning; Quetiapine Fumarate; Quinolones; Risperidone	2005
Schizophrenia. Clinical evidence, 2005, Issue:14 Topics: Amisulpride; Antipsychotic Agents; Chlorpromazine; Clozapine; Cognitive Behavioral Therapy; Dibenzothiepins; Family Therapy; Haloperidol; Humans; Patient Compliance; Risperidone; Schizophrenia; Secondary Prevention; Sulpiride; Thioridazine	2005
An analysis of safety and tolerability data from controlled, comparative studies of quetiapine in patients with schizophrenia, focusing on extrapyramidal symptoms. Human psychopharmacology, 2007, Volume: 22, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Dibenzothiazepines; Female; Haloperidol; Humans; Incidence; Male; Middle Aged; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia	2007
Levomepromazine for schizophrenia. The Cochrane database of systematic reviews, 2010, Oct-06, Issue:10 Topics: Antipsychotic Agents; Chlorpromazine; Humans; Methotrimeprazine; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia	2010
Chlorpromazine versus atypical antipsychotic drugs for schizophrenia. The Cochrane database of systematic reviews, 2016, Apr-05, Volume: 4 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Humans; Olanzapine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia	2016
Wendan decoction (Traditional Chinese medicine) for schizophrenia. The Cochrane database of systematic reviews, 2017, 06-28, Volume: 6 Topics: Antipsychotic Agents; Chlorpromazine; Drug Therapy, Combination; Drugs, Chinese Herbal; Dyskinesia, Drug-Induced; Humans; Patient Satisfaction; Quality of Life; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia	2017

Trials

7 trial(s) available for risperidone and chlorpromazine

Article	Year
A study of enhanced management in patients with treatment-resistant schizophrenia. Journal of psychopharmacology (Oxford, England), 1997, Volume: 11, Issue:4 Topics: Adult; Antipsychotic Agents; Chlorpromazine; Drug Resistance; Female; Humans; Male; Psychiatric Status Rating Scales; Psychotherapy; Risperidone; Schizophrenia; Schizophrenic Psychology; Video Recording	1997
Electroencephalographic and psychomotor effects of chlorpromazine and risperidone relative to placebo in normal healthy volunteers. British journal of clinical pharmacology, 1999, Volume: 48, Issue:3 Topics: Adolescent; Adult; Antipsychotic Agents; Chlorpromazine; Cross-Over Studies; Double-Blind Method; Drug Interactions; Electroencephalography; Eye; Humans; Male; Psychomotor Performance; Risperidone; Sleep Stages; Time Factors	1999
A prospective 4-5 year follow-up of juvenile onset bipolar disorder. Bipolar disorders, 2004, Volume: 6, Issue:5 Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Chlorpromazine; Diagnostic and Statistical Manual of Mental Disorders; Drug Administration Schedule; Female; Follow-Up Studies; Haloperidol; Humans; Imipramine; Lithium Carbonate; Male; Phenotype; Prospective Studies; Recovery of Function; Risperidone; Secondary Prevention; Severity of Illness Index; Valproic Acid	2004
A pharmaco-EEG study on antipsychotic drugs in healthy volunteers. Psychopharmacology, 2007, Volume: 191, Issue:4 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cross-Over Studies; Dibenzothiazepines; Electroencephalography; Fourier Analysis; Haloperidol; Humans; Indoles; Isoindoles; Male; Olanzapine; Quetiapine Fumarate; Reference Values; Risperidone; Single-Blind Method; Thiazoles; Time Factors	2007
Prolactin level during 5 years of risperidone treatment in patients with psychotic disorders. Acta psychiatrica Scandinavica, 2007, Volume: 115, Issue:4 Topics: Antipsychotic Agents; Body Mass Index; Body Weight; Chlorpromazine; Female; Follow-Up Studies; Humans; Longitudinal Studies; Male; Prolactin; Psychotic Disorders; Risperidone; Sex Characteristics	2007
Huperzine A as add-on therapy in patients with treatment-resistant schizophrenia: an open-labeled trial. Schizophrenia research, 2007, Volume: 92, Issue:1-3 Topics: Adolescent; Adult; Aged; Alkaloids; Antipsychotic Agents; Chlorpromazine; Cholinesterase Inhibitors; Clozapine; Drug Resistance; Drug Synergism; Female; Humans; Male; Middle Aged; Risperidone; Schizophrenia; Sesquiterpenes	2007
Ghrelin and leptin response to oral glucose challenge among antipsychotic drug-treated children. Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:6 Topics: Administration, Oral; Adolescent; Age Factors; Analysis of Variance; Antipsychotic Agents; Aripiprazole; Attention Deficit and Disruptive Behavior Disorders; Blood Glucose; Body Mass Index; Child; Chlorpromazine; Fasting; Female; Ghrelin; Glucose; Glucose Tolerance Test; Humans; Insulin; Leptin; Male; Piperazines; Quinolones; Risperidone; Sex Factors; Time Factors; Weight Gain	2007

Other Studies

88 other study(ies) available for risperidone and chlorpromazine

Article	Year
Pyrrole mannich bases as potential antipsychotic agents. Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3 Topics: Animals; Antipsychotic Agents; Avoidance Learning; Male; Mannich Bases; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship	1992
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3 Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin	1994
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. Journal of neurochemistry, 1996, Volume: 66, Issue:1 Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity	1996
Creation of a constitutively activated state of the 5-hydroxytryptamine2A receptor by site-directed mutagenesis: inverse agonist activity of antipsychotic drugs. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1 Topics: Animals; Antipsychotic Agents; COS Cells; Mutagenesis, Site-Directed; Phosphatidylinositols; Protein Conformation; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship	1998
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study. European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3 Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes	1998
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1 Topics: Animals; Antipsychotic Agents; COS Cells; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Receptor Agonists	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
In vitro P-glycoprotein affinity for atypical and conventional antipsychotics. Life sciences, 2002, May-31, Volume: 71, Issue:2 Topics: Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzodiazepines; Binding, Competitive; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Humans; Kinetics; Olanzapine; Pirenzepine; Quetiapine Fumarate; Recombinant Proteins; Risperidone	2002
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers. Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18 Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2002
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3 Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain	2003
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
A two-state homology model of the hERG K+ channel: application to ligand binding. Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation	2005
Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs. Psychopharmacology, 2005, Volume: 179, Issue:2 Topics: Amino Acid Substitution; Antipsychotic Agents; Cell Line; Cyclic AMP; Humans; Mutagenesis, Site-Directed; Mutation; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection	2005
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery. Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19 Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs. Journal of medicinal chemistry, 2007, Oct-18, Volume: 50, Issue:21 Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzoxazines; Biogenic Monoamines; Humans; Hyperprolactinemia; Indoles; Metabolic Diseases; Phthalimides; Piperazines; Principal Component Analysis; Pyridines; Radioligand Assay; Receptors, Biogenic Amine; Weight Gain	2007
BK Virus replication in vitro: limited effect of drugs interfering with viral uptake and intracellular transport. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12 Topics: Antiviral Agents; BK Virus; Cell Line; Chloroquine; Humans; Microbial Sensitivity Tests; Molecular Structure; Nystatin; Virus Replication	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers. European journal of medicinal chemistry, 2009, Volume: 44, Issue:5 Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship	2009
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution	2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Which metabolites circulate? Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5 Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations	2013
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia. Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11 Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides	2014
Serotonin2 receptor-mediated excitation of interneurons in piriform cortex: antagonism by atypical antipsychotic drugs. Neuroscience, 1994, Volume: 58, Issue:3 Topics: Action Potentials; Animals; Antipsychotic Agents; Bicuculline; Cerebral Cortex; Chlorpromazine; Clozapine; Electrophysiology; gamma-Aminobutyric Acid; Haloperidol; In Vitro Techniques; Interneurons; Isoxazoles; Male; Membrane Potentials; Piperidines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Risperidone; Serotonin Antagonists	1994
Agitated behavior relieved following treatment of cervical dystonia in dementia. Neurology, 1995, Volume: 45, Issue:2 Topics: Alzheimer Disease; Botulinum Toxins; Chlorpromazine; Dystonia; Female; Humans; Isoxazoles; Middle Aged; Neck Muscles; Phenytoin; Piperidines; Risperidone; Valproic Acid	1995
Effects of atypical antipsychotic agents on social behavior in rodents. Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Catalepsy; Chlorpromazine; Clozapine; Diazepam; Haloperidol; Isoxazoles; Male; Mice; Mice, Inbred Strains; Piperidines; Raclopride; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Salicylamides; Social Behavior	1993
[A study on the pharmacological properties of atypical antipsychotic drugs: in vivo dopamine and serotonin receptor occupancy by atypical antipsychotic drugs in the rat brain]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1993, Volume: 68, Issue:4 Topics: Animals; Antipsychotic Agents; Autoradiography; Brain; Chlorpromazine; Clozapine; Dibenzothiepins; Flupenthixol; Haloperidol; In Vitro Techniques; Isoxazoles; Male; Piperidines; Pyrimidinones; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Risperidone	1993
Olanzapine. Keep an eye on this neuroleptic. Canadian family physician Medecin de famille canadien, 2000, Volume: 46 Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clinical Trials as Topic; Dopamine Antagonists; Double-Blind Method; Haloperidol; Humans; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists	2000
The discriminative stimulus properties of the atypical antipsychotic olanzapine in rats. Psychopharmacology, 2000, Volume: 148, Issue:3 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Discrimination Learning; Generalization, Psychological; Haloperidol; Male; Olanzapine; Pirenzepine; Raclopride; Rats; Rats, Sprague-Dawley; Risperidone; Ritanserin; Scopolamine	2000
Differential effects of subchronic treatments with atypical antipsychotic drugs on dopamine D2 and serotonin 5-HT2A receptors in the rat brain. Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:3 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain Chemistry; Chlorpromazine; Dopamine Antagonists; Dose-Response Relationship, Drug; Humans; Indoles; Isoindoles; Male; Olanzapine; Pirenzepine; Protein Binding; Quinolines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Selective Serotonin Reuptake Inhibitors; Thiazoles	2000
Tardive dystonia provoked by concomitantly administered risperidone. Psychiatry and clinical neurosciences, 2000, Volume: 54, Issue:4 Topics: Adolescent; Antipsychotic Agents; Chlorpromazine; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Hypotension; Middle Aged; Parkinson Disease, Secondary; Risperidone; Schizophrenia	2000
Olanzapine: new preparation. Keep an eye on this neuroleptic. Prescrire international, 1999, Volume: 8, Issue:43 Topics: Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Humans; Pirenzepine; Risperidone; Schizophrenia; Treatment Outcome	1999
Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine efflux in the hippocampus of the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 26, Issue:5 Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Dialysis Solutions; Dopamine Antagonists; Extracellular Space; Haloperidol; Hippocampus; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Microdialysis; Olanzapine; Piperazines; Pirenzepine; Rats; Rats, Wistar; Risperidone; Serotonin Antagonists; Thiazoles; Thioridazine	2002
Glucose intolerance with atypical antipsychotics. Drug safety, 2002, Volume: 25, Issue:15 Topics: Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Chlorpromazine; Clozapine; Diabetes Mellitus; Glucose Intolerance; Haloperidol; Humans; Hyperglycemia; Olanzapine; Pirenzepine; Risk Factors; Risperidone; World Health Organization	2002
Discriminative stimulus properties in rats of the novel antipsychotic quetiapine. Experimental and clinical psychopharmacology, 2002, Volume: 10, Issue:4 Topics: Amisulpride; Analysis of Variance; Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Dibenzothiazepines; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Generalization, Psychological; Haloperidol; Loxapine; Quetiapine Fumarate; Quinoxalines; Rats; Rats, Wistar; Risperidone; Sulpiride	2002
Acute massive pulmonary thromboembolism associated with risperidone and conventional phenothiazines. Circulation journal : official journal of the Japanese Circulation Society, 2003, Volume: 67, Issue:1 Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Dopamine Antagonists; Female; Humans; Japan; Male; Middle Aged; Phenothiazines; Pulmonary Embolism; Risperidone; Severity of Illness Index; Sex Distribution; Thromboembolism	2003
alpha2C-Adrenoceptor blockade by clozapine and other antipsychotic drugs. European journal of pharmacology, 2003, Feb-21, Volume: 462, Issue:1-3 Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brimonidine Tartrate; Chlorpromazine; CHO Cells; Clozapine; Cricetinae; Cyclic AMP; Dibenzothiazepines; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Gene Expression; Haloperidol; Humans; Isoxazoles; Norepinephrine; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Quinolones; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Risperidone; Thiazoles; Transfection; Yohimbine	2003
Comparative behavioural effects of typical and atypical antipsychotic drugs in rhesus monkey. European journal of pharmacology, 2003, Feb-21, Volume: 462, Issue:1-3 Topics: Administration, Oral; Animals; Antipsychotic Agents; Behavior, Animal; Chlorpromazine; Dose-Response Relationship, Drug; Drinking Behavior; Feeding Behavior; Female; Haloperidol; Injections, Intramuscular; Macaca mulatta; Male; Motor Activity; Risperidone; Social Behavior; Time Factors; Videotape Recording	2003
Antipsychotics increase microtubule-associated protein 2 mRNA but not spinophilin mRNA in rat hippocampus and cortex. Journal of neuroscience research, 2004, May-01, Volume: 76, Issue:3 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Cerebral Cortex; Chlorpromazine; Clozapine; Gene Expression Regulation; Haloperidol; Hippocampus; In Situ Hybridization; Male; Microfilament Proteins; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurites; Olanzapine; Rats; Rats, Sprague-Dawley; Risperidone; RNA, Messenger; Tissue Distribution	2004
Combined treatment of quetiapine with haloperidol in animal models of antipsychotic effect and extrapyramidal side effects: comparison with risperidone and chlorpromazine. Psychopharmacology, 2004, Volume: 176, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Catalepsy; Chlorpromazine; Dibenzothiazepines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Haloperidol; Hyperkinesis; Injections, Intraperitoneal; Male; Methamphetamine; Mice; Piperazines; Pyridines; Quetiapine Fumarate; Receptor, Serotonin, 5-HT1A; Risperidone; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists	2004
Effects of amisulpride, risperidone and chlorpromazine on auditory and visual latent inhibition, prepulse inhibition, executive function and eye movements in healthy volunteers. Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:2 Topics: Acoustic Stimulation; Administration, Oral; Adult; Akathisia, Drug-Induced; Amisulpride; Blood Pressure; Chlorpromazine; Controlled Clinical Trials as Topic; Demography; Double-Blind Method; Eye Movements; Humans; Male; Neuropsychological Tests; Photic Stimulation; Problem Solving; Reaction Time; Reflex, Startle; Risperidone; Space Perception; Sulpiride; Verbal Behavior	2004
Effect of switching antipsychotics on antiparkinsonian medication use in schizophrenia: population-based study. The British journal of psychiatry : the journal of mental science, 2005, Volume: 187 Topics: Adult; Age Factors; Aged; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Chlorpromazine; Dopamine Antagonists; Drug Administration Schedule; Family Practice; Female; Haloperidol; Humans; Male; Middle Aged; Olanzapine; Risperidone; Schizophrenia; Sex Factors	2005
[No association of -1438G/A polymorphism in promoter region of 5-HT2A receptor gene with antipsychotic agent-induced weight gain]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2005, Volume: 22, Issue:5 Topics: Adult; Antipsychotic Agents; Chlorpromazine; Female; Gene Frequency; Genotype; Humans; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Promoter Regions, Genetic; Receptor, Serotonin, 5-HT2A; Risperidone; Schizophrenia; Weight Gain	2005
Differential effects of long-term treatment with typical and atypical antipsychotics on NGF and BDNF levels in rat striatum and hippocampus. Schizophrenia research, 2006, Feb-15, Volume: 82, Issue:1 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain-Derived Neurotrophic Factor; Chlorpromazine; Corpus Striatum; Haloperidol; Hippocampus; Male; Nerve Growth Factor; Olanzapine; Rats; Rats, Wistar; Risperidone; Time	2006
Long-term antipsychotic treatments and crossover studies in rats: differential effects of typical and atypical agents on the expression of antioxidant enzymes and membrane lipid peroxidation in rat brain. Journal of psychiatric research, 2007, Volume: 41, Issue:5 Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chlorpromazine; Clozapine; Cross-Over Studies; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Haloperidol; Lipid Peroxidation; Male; Membrane Lipids; Olanzapine; Rats; Rats, Wistar; Risperidone; Schizophrenia; Superoxide Dismutase	2007
Prototypical antipsychotic drugs protect hippocampal neuronal cultures against cell death induced by growth medium deprivation. BMC neuroscience, 2006, Mar-30, Volume: 7 Topics: Animals; Anisoles; Antipsychotic Agents; Benzazepines; Butaclamol; Caspase Inhibitors; Cell Death; Cells, Cultured; Chlorpromazine; Clozapine; Domperidone; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Ginkgo biloba; Haloperidol; Hippocampus; Indans; Isoxazoles; Neurons; Neuroprotective Agents; Peptides; Piperidines; Plant Extracts; Propylamines; Raclopride; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Remoxipride; Risperidone; Sulpiride	2006
Priapism associated with typical and atypical antipsychotic medications. International clinical psychopharmacology, 2006, Volume: 21, Issue:4 Topics: Adrenergic alpha-Antagonists; Adult; Antipsychotic Agents; Chlorpromazine; Humans; Male; Priapism; Risperidone; Schizophrenia	2006
Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein. Psychopharmacology, 2006, Volume: 187, Issue:4 Topics: Animals; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzodiazepines; Chlorpromazine; Clozapine; Cyclosporins; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Flow Cytometry; Fluorescent Dyes; Haloperidol; Isoxazoles; Kidney; Liver; LLC-PK1 Cells; Olanzapine; Paliperidone Palmitate; Pyrimidines; Quetiapine Fumarate; Rhodamine 123; Risperidone; Swine; Transfection	2006
Relative risk of glucose elevation during antipsychotic exposure in a Veterans Administration population. International clinical psychopharmacology, 2007, Volume: 22, Issue:1 Topics: Antipsychotic Agents; Benzodiazepines; Blood Glucose; Chlorpromazine; Cohort Studies; Female; Fluphenazine; Haloperidol; Hospitals, Veterans; Humans; Hyperglycemia; Incidence; Male; Middle Aged; Olanzapine; Perphenazine; Retrospective Studies; Risk Assessment; Risk Factors; Risperidone; Southeastern United States; Time Factors; Veterans	2007
Comparative neurochemical changes associated with chronic administration of typical and atypical neuroleptics: implications in tardive dyskinesia. Indian journal of experimental biology, 2007, Volume: 45, Issue:2 Topics: Animals; Antipsychotic Agents; Body Weight; Chlorpromazine; Clozapine; Dopamine; Dyskinesia, Drug-Induced; Haloperidol; Male; Norepinephrine; Prosencephalon; Rats; Rats, Wistar; Risperidone; Serotonin	2007
Neuroleptic malignant syndrome and catatonia in a patient with dementia. The Australian and New Zealand journal of psychiatry, 2008, Volume: 42, Issue:6 Topics: Aged; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Catatonia; Chlorpromazine; Cholinesterase Inhibitors; Cognition Disorders; Creatine Kinase; Dementia; Disease Progression; Donepezil; Female; Humans; Indans; Lorazepam; Muscle Rigidity; Neuroleptic Malignant Syndrome; Olanzapine; Piperidines; Recurrence; Risperidone	2008
Acute respiratory distress due to antipsychotic drugs. Pharmacopsychiatry, 2010, Volume: 43, Issue:3 Topics: Adult; Antiparkinson Agents; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Drug Therapy, Combination; Dystonia; Fatal Outcome; Haloperidol; Humans; Larynx; Male; Olanzapine; Respiratory Distress Syndrome; Respiratory Insufficiency; Risperidone; Schizophrenia	2010
Contributions to the study of morphofunctional interrelations in the liver of the rats treated with certain antipsychotic drugs. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2011, Volume: 52, Issue:1 Suppl Topics: Animals; Antipsychotic Agents; Chlorpromazine; Haloperidol; Liver; Male; Rats; Rats, Wistar; Risperidone	2011
Risperidone-induced Pisa syndrome in MS: resolution with lurasidone and recurrence with Chlorpromazine. The Annals of pharmacotherapy, 2013, Volume: 47, Issue:9 Topics: Adult; Antipsychotic Agents; Child Development Disorders, Pervasive; Chlorpromazine; Gait Ataxia; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Multiple Sclerosis; Recurrence; Risperidone; Syndrome; Thiazoles	2013
Adverse effects of antipsychotics on micro-vascular endothelial cells of the human blood-brain barrier. Brain research, 2014, Oct-02, Volume: 1583 Topics: Antipsychotic Agents; Apoptosis; Blood-Brain Barrier; Capillary Permeability; Caspase 3; Caspase 8; Caspase 9; Cell Survival; Cells, Cultured; Chlorpromazine; Clozapine; DNA Breaks; Endothelial Cells; Haloperidol; Humans; Microvessels; Oxidative Stress; Reactive Oxygen Species; Risperidone	2014
A systematic microdialysis study of dopamine transmission in the accumbens shell/core and prefrontal cortex after acute antipsychotics. Psychopharmacology, 2015, Volume: 232, Issue:8 Topics: Administration, Intravenous; Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Dopamine; Haloperidol; Male; Microdialysis; Nucleus Accumbens; Prefrontal Cortex; Raclopride; Rats; Rats, Sprague-Dawley; Risperidone; Time Factors	2015
A Cost-effectiveness Analysis of Antipsychotics for Treatment of Schizophrenia in Uganda. Applied health economics and health policy, 2015, Volume: 13, Issue:5 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cost-Benefit Analysis; Drug Costs; Haloperidol; Health Care Costs; Humans; Middle Aged; Olanzapine; Quality-Adjusted Life Years; Risperidone; Schizophrenia; Uganda	2015
Association studies of genomic variants with treatment response to risperidone, clozapine, quetiapine and chlorpromazine in the Chinese Han population. The pharmacogenomics journal, 2016, Volume: 16, Issue:4 Topics: Adolescent; Adult; Antipsychotic Agents; Asian People; Chi-Square Distribution; China; Chlorpromazine; Clozapine; Cross-Sectional Studies; Female; Genetic Association Studies; Haplotypes; Humans; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Pharmacogenomic Testing; Pharmacogenomic Variants; Phenotype; Polymorphism, Single Nucleotide; Predictive Value of Tests; Quetiapine Fumarate; Reelin Protein; Risk Factors; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; Young Adult	2016
Risperidone, quetiapine and chlorpromazine may have induced priapism in an adolescent. Pediatrics international : official journal of the Japan Pediatric Society, 2016, Volume: 58, Issue:1 Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Chlorpromazine; Drug Therapy, Combination; Humans; Male; Penis; Priapism; Quetiapine Fumarate; Risperidone; Ultrasonography, Doppler	2016
Risk of Mortality Among Patients Treated With Antipsychotic Medications: A Nationwide Population-Based Study in Taiwan. Journal of clinical psychopharmacology, 2016, Volume: 36, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Chlorpromazine; Critical Illness; Female; Follow-Up Studies; Haloperidol; Humans; Male; Middle Aged; Mortality; Proportional Hazards Models; Quetiapine Fumarate; Retrospective Studies; Risk Factors; Risperidone; Taiwan; Time Factors; Young Adult	2016
Risperidone long-acting injectable in the treatment of treatment-resistant schizophrenia with dopamine supersensitivity psychosis: Results of a 2-year prospective study, including an additional 1-year follow-up. Journal of psychopharmacology (Oxford, England), 2016, Volume: 30, Issue:8 Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Chlorpromazine; Delayed-Action Preparations; Dopamine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Injections; Male; Middle Aged; Prospective Studies; Psychiatric Status Rating Scales; Psychoses, Substance-Induced; Receptors, Dopamine D2; Risperidone; Schizophrenia; Young Adult	2016
Different influence of antipsychotics on the balance between pro- and anti-inflammatory cytokines depends on glia activation: An in vitro study. Cytokine, 2017, Volume: 94 Topics: Animals; Antipsychotic Agents; Cell Differentiation; Cell Survival; Cells, Cultured; Chlorpromazine; Culture Media; Cytokines; Haloperidol; In Vitro Techniques; Inflammation; Interleukin-10; Interleukin-1beta; Lipopolysaccharides; Neuroglia; Rats; Risperidone; Tumor Necrosis Factor-alpha	2017
Risperidone versus olanzapine in the acute treatment of Persistent Delusional Disorder: A retrospective analysis. Psychiatry research, 2017, Volume: 253 Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Female; Humans; Logistic Models; Male; Middle Aged; Olanzapine; Prospective Studies; Retrospective Studies; Risperidone; Schizophrenia, Paranoid; Treatment Outcome	2017
The role of oxidative stress in antipsychotics induced ovarian toxicity. Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 44 Topics: Animals; Antipsychotic Agents; Caspases; Cell Survival; Cells, Cultured; Chlorpromazine; Clozapine; Female; Glutathione; Haloperidol; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Risperidone; Theca Cells	2017
Clozapine, chlorpromazine and risperidone dose-dependently reduce emotional hyperthermia, a biological marker of salience. Psychopharmacology, 2017, Volume: 234, Issue:21 Topics: Animals; Arousal; Chlorpromazine; Clozapine; Dose-Response Relationship, Drug; Emotions; Fever; Male; Rats; Rats, Sprague-Dawley; Risperidone; Thermogenesis; Vasoconstriction	2017
Anticholinergic Load and Nutritional Status in Older Individuals. The journal of nutrition, health & aging, 2020, Volume: 24, Issue:1 Topics: Aged; Aged, 80 and over; Chlorpromazine; Cholinergic Antagonists; Female; Geriatric Assessment; Haloperidol; Hospitalization; Humans; Hydroxyzine; Japan; Linear Models; Longitudinal Studies; Male; Malnutrition; Metoclopramide; Multivariate Analysis; Nutrition Assessment; Nutritional Status; Patient Discharge; Regression Analysis; Retrospective Studies; Risperidone	2020
Serotonin 2A (5-HT Scientific reports, 2020, 12-10, Volume: 10, Issue:1 Topics: Amphetamines; Animals; Antipsychotic Agents; Cell-Matrix Junctions; Chlorpromazine; HEK293 Cells; Humans; Mental Disorders; Olanzapine; Rats; Receptor, Serotonin, 5-HT2A; Risperidone; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Stress Fibers	2020
Prevalence of antipsychotic-induced extrapyramidal symptoms and their association with neurocognition and social cognition in outpatients with schizophrenia in the "real-life". Progress in neuro-psychopharmacology & biological psychiatry, 2021, 07-13, Volume: 109 Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Cognition; Female; Humans; Male; Middle Aged; Prevalence; Risperidone; Schizophrenia; Schizophrenic Psychology; Social Cognition	2021
A Case Report of Stuttering Induced by Risperidone and Chlorpromazine. Psychopharmacology bulletin, 2022, 02-25, Volume: 52, Issue:1 Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Haloperidol; Humans; Male; Risperidone; Stuttering	2022
Letter to the Editor: Rethinking The Cost Of Antipsychotic Treatment: The Average Cost Of The Drugs Used In Turkey In 2020. Turk psikiyatri dergisi = Turkish journal of psychiatry, 2022,Summer, Volume: 33, Issue:2 Topics: Adenosine Monophosphate; Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chlorpromazine; Clopenthixol; Clozapine; Flupenthixol; Fluphenazine; Haloperidol; Humans; Olanzapine; Paliperidone Palmitate; Pharmaceutical Preparations; Pimozide; Quetiapine Fumarate; Risperidone; Sulpiride; Trifluoperazine	2022