rimocidin and dithiane

rimocidin has been researched along with dithiane* in 2 studies

Other Studies

2 other study(ies) available for rimocidin and dithiane

Article	Year
(+)-Rimocidin synthetic studies: construction of the C(1-27) aglycone skeleton. The Journal of organic chemistry, 2009, Aug-21, Volume: 74, Issue:16 Assembly of the C(1-27) macrocyclic skeleton of rimocidinolide, the aglycone of (+)-rimocidin (1), has been achieved in convergent fashion. Key features of the synthetic strategy entail application of multicomponent Type I Anion Relay Chemistry (ARC), in conjunction with the S(N)2/S(N)2' reaction manifolds of vinyl epoxides, both employing 2-substituted 1,3-dithianes to construct the C(1-19) carbon backbone. Yamaguchi union of a C(20-27) vinyl borate ester, possessing the all-trans triene, with an advanced C(1-19) vinyl iodide followed by macrocyclization via Suzuki-Miyaura cross-coupling completed construction of the C(1-27) rimocidinolide skeleton. Topics: Borates; Carboxylic Acids; Epoxy Compounds; Macrocyclic Compounds; Polyenes; Pyrans; Quinolizines; Stereoisomerism; Sulfur Compounds	2009
(+)-Rimocidin synthetic studies. Construction of an advanced C(1-18) polyol fragment. Organic letters, 2003, Jul-24, Volume: 5, Issue:15 [structure: see text] The synthesis of an appropriately functionalized advanced C(1-18) polyol fragment of the mycosamine-glycosylated polyene macrolide, (+)-rimocidin (1), has been achieved in a highly efficient manner. Highlights of the strategy include the S(N)2/S(N)2' addition of dithiane anions to vinyl epoxides and the multicomponent linchpin union of 2-TBS-1,3-dithiane with two advanced epoxides. Topics: Alkaloids; Epoxy Compounds; Polyenes; Polymers; Quinolizines; Stereoisomerism; Sulfur Compounds	2003

Article

Year

(+)-Rimocidin synthetic studies: construction of the C(1-27) aglycone skeleton.

The Journal of organic chemistry, 2009, Aug-21, Volume: 74, Issue:16

Assembly of the C(1-27) macrocyclic skeleton of rimocidinolide, the aglycone of (+)-rimocidin (1), has been achieved in convergent fashion. Key features of the synthetic strategy entail application of multicomponent Type I Anion Relay Chemistry (ARC), in conjunction with the S(N)2/S(N)2' reaction manifolds of vinyl epoxides, both employing 2-substituted 1,3-dithianes to construct the C(1-19) carbon backbone. Yamaguchi union of a C(20-27) vinyl borate ester, possessing the all-trans triene, with an advanced C(1-19) vinyl iodide followed by macrocyclization via Suzuki-Miyaura cross-coupling completed construction of the C(1-27) rimocidinolide skeleton.

Topics: Borates; Carboxylic Acids; Epoxy Compounds; Macrocyclic Compounds; Polyenes; Pyrans; Quinolizines; Stereoisomerism; Sulfur Compounds

2009

(+)-Rimocidin synthetic studies. Construction of an advanced C(1-18) polyol fragment.

Organic letters, 2003, Jul-24, Volume: 5, Issue:15

[structure: see text] The synthesis of an appropriately functionalized advanced C(1-18) polyol fragment of the mycosamine-glycosylated polyene macrolide, (+)-rimocidin (1), has been achieved in a highly efficient manner. Highlights of the strategy include the S(N)2/S(N)2' addition of dithiane anions to vinyl epoxides and the multicomponent linchpin union of 2-TBS-1,3-dithiane with two advanced epoxides.

Topics: Alkaloids; Epoxy Compounds; Polyenes; Polymers; Quinolizines; Stereoisomerism; Sulfur Compounds

2003