riluzole and diazepam
riluzole has been researched along with diazepam in 13 studies
Research
Studies (13)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| D'Angio, M; Scatton, B; Serrano, A | 1 |
| Benavides, J; Camelin, JC; Flamand, F; Gueremy, C; Le Fur, G; Legrand, JJ; Mitrani, N; Uzan, A | 1 |
| Bernardi, G; Caramia, MD; Desiato, MT; Iani, C; Palmieri, MG; Scalise, A; Telera, S | 1 |
| Balster, RL; Wiley, JL | 1 |
| Inagaki, M; Iwai, T; Oka, J; Saitoh, A; Sasaki-Hamada, S; Sugiyama, A; Takahashi, K; Yamada, M | 1 |
| Iijima, T; Inagaki, M; Oka, J; Sacai, H; Saitoh, A; Sasaki-Hamada, S; Sugiyama, A; Yamada, M | 1 |
| Andreasen, SR; Christensen, TB; Holm, MM; Lundbye, CJ; Schmitt-John, T; Thielsen, KD | 1 |
Reviews
1 review(s) available for riluzole and diazepam
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Trials
1 trial(s) available for riluzole and diazepam
| Article | Year |
|---|---|
Pharmacologic reversal of cortical hyperexcitability in patients with ALS.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Cerebral Cortex; Cyclohexanecarboxylic Acids; Diazepam; Drug Therapy, Combination; Evoked Potentials, Motor; Female; GABA Agonists; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetics; Male; Middle Aged; Neural Inhibition; Neuroprotective Agents; Physical Stimulation; Riluzole; Synaptic Transmission; Treatment Outcome | 2000 |
Other Studies
11 other study(ies) available for riluzole and diazepam
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
NMDA antagonists block restraint-induced increase in extracellular DOPAC in rat nucleus accumbens.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Aspartic Acid; Carbolines; Convulsants; Diazepam; Male; N-Methylaspartate; Nucleus Accumbens; Phenylacetates; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Restraint, Physical; Riluzole; Septal Nuclei; Thiazoles | 1989 |
2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission--II. Biochemical properties.
Topics: Acetylcholine; Amino Acids; Animals; Anticonvulsants; Apomorphine; Cerebellum; Chlordiazepoxide; Cyclic GMP; Diazepam; gamma-Aminobutyric Acid; Harmaline; In Vitro Techniques; Injections, Intraventricular; Isoniazid; Male; Rats; Rats, Inbred Strains; Riluzole; Synaptic Transmission; Thiazoles | 1985 |
Effects of modulators of N-methyl-D-aspartate receptor-mediated neurotransmission on diazepam discrimination in rats.
Topics: Amino Acids; Animals; Biguanides; Binding Sites; Conditioning, Operant; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agonists; Male; N-Methylaspartate; Pentobarbital; Phencyclidine; Piperazines; Quinolones; Quinoxalines; Rats; Rats, Sprague-Dawley; Riluzole | 2004 |
Riluzole produces distinct anxiolytic-like effects in rats without the adverse effects associated with benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzodiazepines; Diazepam; Exploratory Behavior; Male; Motor Activity; Rats; Rats, Wistar; Riluzole | 2012 |
Riluzole does not affect hippocampal synaptic plasticity and spatial memory, which are impaired by diazepam in rats.
Topics: Amnesia; Animals; Anti-Anxiety Agents; Diazepam; Hippocampus; Male; Memory; Memory Disorders; Neuronal Plasticity; Neuroprotective Agents; Rats; Rats, Wistar; Riluzole; Synapses | 2013 |
Excitatory-inhibitory imbalance in the brain of the wobbler mouse model of amyotrophic lateral sclerosis substantiated by riluzole and diazepam.
Topics: Amyotrophic Lateral Sclerosis; Animals; Diazepam; Disease Models, Animal; Hippocampus; Mice, Inbred C57BL; Neurodegenerative Diseases; Riluzole | 2017 |