rifampin has been researched along with saringosterol* in 1 studies
1 other study(ies) available for rifampin and saringosterol
Article | Year |
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Inhibition of Mycobacterium tuberculosis growth by saringosterol from Lessonia nigrescens.
Assay-guided fractionation of an antitubercular extract obtained from Lessonia nigrescens yielded the phytosterol saringosterol as its active component. No appreciable toxicity against Vero cells was observed for this compound. Saringosterol was also synthesized by oxidation of fucosterol. The MIC values for antitubercular activity of saringosterol and its 24S and 24R epimers were determined as 0.25, 1, and 0.125 microg/mL. Topics: Animals; Antitubercular Agents; Cells, Cultured; Chile; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Phaeophyceae; Stereoisomerism; Stigmasterol; Vero Cells | 2001 |