rifampin and propyleneimine

rifampin has been researched along with propyleneimine* in 1 studies

Other Studies

1 other study(ies) available for rifampin and propyleneimine

Article	Year
PEGylated dendritic architecture for development of a prolonged drug delivery system for an antitubercular drug. Current drug delivery, 2007, Volume: 4, Issue:1 The present study was aimed at developing and exploring the use of PEGylated poly (propylene imine) dendritic architecture for the delivery of an anti-tuberculosis drug, rifampicin. For this study, PEGylated poly(propylene imine) dendritic architecture was synthesized and loaded with rifampicin. Various physicochemical and physiological parameters UV, IR, NMR, TEM, DSC, drug entrapment, drug release and hemolytic toxicity of both PEGylated and non-PEGylated systems were determined and compared. The PEGylation of the systems was found to have increased their drug-loading capacity, reduced their drug release rate and hemolytic toxicity. The systems were found suitable for prolonged delivery of rifampicin. Topics: Antitubercular Agents; Aziridines; Calorimetry, Differential Scanning; Delayed-Action Preparations; Dendrimers; Drug Delivery Systems; Drug Stability; Drug Storage; Erythrocytes; Humans; Magnetic Resonance Spectroscopy; Microscopy, Electron, Transmission; Models, Chemical; Particle Size; Rifampin; Spectrophotometry, Infrared; Technology, Pharmaceutical; Temperature; Time Factors; Ultraviolet Rays	2007

Article

Year

PEGylated dendritic architecture for development of a prolonged drug delivery system for an antitubercular drug.

Current drug delivery, 2007, Volume: 4, Issue:1

The present study was aimed at developing and exploring the use of PEGylated poly (propylene imine) dendritic architecture for the delivery of an anti-tuberculosis drug, rifampicin. For this study, PEGylated poly(propylene imine) dendritic architecture was synthesized and loaded with rifampicin. Various physicochemical and physiological parameters UV, IR, NMR, TEM, DSC, drug entrapment, drug release and hemolytic toxicity of both PEGylated and non-PEGylated systems were determined and compared. The PEGylation of the systems was found to have increased their drug-loading capacity, reduced their drug release rate and hemolytic toxicity. The systems were found suitable for prolonged delivery of rifampicin.

Topics: Antitubercular Agents; Aziridines; Calorimetry, Differential Scanning; Delayed-Action Preparations; Dendrimers; Drug Delivery Systems; Drug Stability; Drug Storage; Erythrocytes; Humans; Magnetic Resonance Spectroscopy; Microscopy, Electron, Transmission; Models, Chemical; Particle Size; Rifampin; Spectrophotometry, Infrared; Technology, Pharmaceutical; Temperature; Time Factors; Ultraviolet Rays

2007