rifampin has been researched along with plumieride* in 1 studies
1 other study(ies) available for rifampin and plumieride
| Article | Year |
|---|---|
Immunostimulatory activity of plumieride an iridoid in augmenting immune system by targeting Th-1 pathway in balb/c mice.
Plumieride, an iridoid glucoside isolated from Plumieria acutifolia leaves was investigated for its immunostimulatory activity on humoral, cell mediated and intracellular cytokine levels in sensitized and unsensitised balb/c mice. Plumieride restores the suppressed cell mediated, humoral immune response and also enhances the release of TNF- α, IFN-γ, and IL-2 (Th-1) in immune compromised cyclosporine and cyclophosphamide treated balb/c mice. It does not stimulate the IL-4 (Th-2) expression. Plumieride demonstrates significant augmentation of Th-1 response in immunosuppressed balb/c mice. Results of the present study suggested that plumieride can be developed as an immunostimulatory adjuvant to treat the immune suppression in various disease condition(s). Topics: Adjuvants, Immunologic; Animals; Antibiotics, Antitubercular; Antigens; B-Lymphocytes; Cyclosporine; Cytokines; Drug Synergism; Erythrocytes; Female; Furans; Graft Rejection; Hypersensitivity, Delayed; Macrophages, Peritoneal; Mice, Inbred BALB C; Mycobacterium tuberculosis; Rifampin; Sheep; Skin Transplantation; Spiro Compounds; Spleen; T-Lymphocytes; Tuberculosis | 2017 |