rifampin and methacrylamide

rifampin has been researched along with methacrylamide* in 1 studies

Other Studies

1 other study(ies) available for rifampin and methacrylamide

Article	Year
Radiation crosslinked polymerization of methacrylamide and psyllium to develop antibiotic drug delivery device. International journal of biological macromolecules, 2009, Nov-01, Volume: 45, Issue:4 Psyllium is a medicinally important polysaccharide and its modification with methacrylamide through radiation crosslinked polymerization will develop hydrogels meant for drug delivery applications. The present paper deals with the preparation of hydrogels and their characterization by SEMs, FTIR, TGA and swelling studies. The release dynamics of model antibiotic drug rifampicin from the hydrogels has been studied for the evaluation of the release mechanism. The values of the diffusion exponent 'n' have been obtained (0.64, 0.58 and 0.57), respectively, in distilled water, pH 2.2 buffer and pH 7.4 buffer. The release of the drug from the hydrogels occurred through non-Fickian diffusion mechanism. Topics: Acrylamides; Anti-Bacterial Agents; Drug Carriers; Hydrogels; Hydrogen-Ion Concentration; Kinetics; Microscopy, Electron, Scanning; Polymers; Psyllium; Radiation; Radiation Dosage; Rifampin; Sodium Chloride; Spectroscopy, Fourier Transform Infrared; Temperature; Thermogravimetry; Water	2009

Article

Year

Radiation crosslinked polymerization of methacrylamide and psyllium to develop antibiotic drug delivery device.

International journal of biological macromolecules, 2009, Nov-01, Volume: 45, Issue:4

Psyllium is a medicinally important polysaccharide and its modification with methacrylamide through radiation crosslinked polymerization will develop hydrogels meant for drug delivery applications. The present paper deals with the preparation of hydrogels and their characterization by SEMs, FTIR, TGA and swelling studies. The release dynamics of model antibiotic drug rifampicin from the hydrogels has been studied for the evaluation of the release mechanism. The values of the diffusion exponent 'n' have been obtained (0.64, 0.58 and 0.57), respectively, in distilled water, pH 2.2 buffer and pH 7.4 buffer. The release of the drug from the hydrogels occurred through non-Fickian diffusion mechanism.

Topics: Acrylamides; Anti-Bacterial Agents; Drug Carriers; Hydrogels; Hydrogen-Ion Concentration; Kinetics; Microscopy, Electron, Scanning; Polymers; Psyllium; Radiation; Radiation Dosage; Rifampin; Sodium Chloride; Spectroscopy, Fourier Transform Infrared; Temperature; Thermogravimetry; Water

2009