rifampin has been researched along with eupomatenoid-5* in 1 studies
1 other study(ies) available for rifampin and eupomatenoid-5
Article | Year |
---|---|
In vitro interaction of eupomatenoid-5 from Piper solmsianum C. DC. var. solmsianum and anti-tuberculosis drugs.
Department of Clinical Analysis and Biomedicine, State University of Maringa, Maringa, Parana, Brazil.. To evaluate the in vitro interaction between eupomatenoid-5 (EUP-5), extracted from Piper solmsianum C. DC. var. solmsianum, and first-line anti-tuberculosis drugs against Mycobacterium tuberculosis H₃₇Rv and 20 clinical isolates.. Resazurin drugs combination microtiter assay (REDCA) was performed to determine the interaction between EUP-5 and isoniazid, rifampicin (RMP) and ethambutol (EMB).. Synergism was observed in M. tuberculosis H₃₇Rv and eight clinical isolates with EUP-5+RMP, and in M. tuberculosis H₃₇Rv and 17 clinical isolates with EUP-5+EMB combinations.. EUP-5 is a promising compound for further studies on the development of anti-tuberculosis drugs. Topics: Antitubercular Agents; Benzofurans; Drug Resistance, Multiple, Bacterial; Drug Synergism; Ethambutol; Genotype; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phenols; Phytotherapy; Piper; Plant Extracts; Plant Leaves; Plants, Medicinal; Rifampin | 2014 |