rifampin and amphoglucamine

rifampin has been researched along with amphoglucamine* in 1 studies

Other Studies

1 other study(ies) available for rifampin and amphoglucamine

Article	Year
[Combined chemotherapy of experimental generalized candidiasis]. Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1987, Volume: 32, Issue:10 It was shown that combined use of the polyene antibiotic amphoglucamine (AMG) and 5-fluorocytosine (5-FC), rifampicin, or methacycline was much more efficient in therapy of experimental generalized candidiasis. Combination of AMG with 5-FC or rifampicin proved to be the most favourable. The use of these combinations resulted in a 7-8-fold increase in the average lifespan of experimental animals, markedly increased their survival and lowered contamination of the internal organs with the fungus. Combination of AMG with 5-FC resulted in complete healing of experimental mice by the end of the treatment. Summation of the antifungal action of the drugs provided the required effect with the polyene dose 2 times lower than the therapeutic one. Topics: Amphotericin B; Animals; Candidiasis; Drug Evaluation, Preclinical; Drug Therapy, Combination; Flucytosine; Methacycline; Mice; Rifampin	1987

Article

Year

[Combined chemotherapy of experimental generalized candidiasis].

Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1987, Volume: 32, Issue:10

It was shown that combined use of the polyene antibiotic amphoglucamine (AMG) and 5-fluorocytosine (5-FC), rifampicin, or methacycline was much more efficient in therapy of experimental generalized candidiasis. Combination of AMG with 5-FC or rifampicin proved to be the most favourable. The use of these combinations resulted in a 7-8-fold increase in the average lifespan of experimental animals, markedly increased their survival and lowered contamination of the internal organs with the fungus. Combination of AMG with 5-FC resulted in complete healing of experimental mice by the end of the treatment. Summation of the antifungal action of the drugs provided the required effect with the polyene dose 2 times lower than the therapeutic one.

Topics: Amphotericin B; Animals; Candidiasis; Drug Evaluation, Preclinical; Drug Therapy, Combination; Flucytosine; Methacycline; Mice; Rifampin

1987