rifampin has been researched along with 5-4--dihydroxy-7-3--dimethoxyflavone* in 1 studies
1 other study(ies) available for rifampin and 5-4--dihydroxy-7-3--dimethoxyflavone
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Antimycobacterial labdane diterpenes from Leucas stelligera.
Phytochemical investigation of the acetone extract of the aerial parts of Leucas stelligera afforded four new compounds (1-4) belonging to the labdane diterpene series as well as two known flavones, velutin (5) and chrysoeriol (6). Structure elucidation of the new compounds was carried out using 1D and 2D NMR spectroscopic data and single-crystal X-ray crystallography of compound 1. Compounds 1-4 exhibited selective antimycobacterial activity against Mycobacterium tuberculosis with IC50 values in the range 5.02-9.80 μg/mL. Topics: Antitubercular Agents; Crystallography, X-Ray; Diterpenes; Drug Screening Assays, Antitumor; Flavones; Hep G2 Cells; Humans; India; Inhibitory Concentration 50; Lamiaceae; Microbial Sensitivity Tests; Molecular Conformation; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular | 2013 |