Page last updated: 2024-08-16

ribavirin and zidovudine

ribavirin has been researched along with zidovudine in 80 studies

Research

Studies (80)

Timeframe	Studies, this research(%)	All Research%
pre-1990	21 (26.25)	18.7374
1990's	15 (18.75)	18.2507
2000's	24 (30.00)	29.6817
2010's	18 (22.50)	24.3611
2020's	2 (2.50)	2.80

Authors

Authors	Studies
Corbett, TH; Court, BA; Kessel, D; Phadtare, S; Renis, HE; Zimlicka, J	1
Baitz-Gács, E; Béres, J; De Clercq, E; Gruber, L; Otvös, L; Sági, G; Tömösközi, I	1
De Clercq, E	1
Andrei, G; Balzarini, J; Blache, Y; Chapat, JP; Chavignon, O; De Clercq, E; Debouzy, JC; Elhakmaoui, A; Essassi, EM; Gueiffier, A; Kerbal, A; Lhassani, M; Snoeck, R; Teulade, JC; Witvrouw, M	1
Balzarini, J; De Clercq, E; Faraj, A; Fedorov, II; Gosselin, G; Gurskaya, GV; Imbach, JL; Jasko, MV; Kazmina, EM; Sommadossi, JP; Zavodnic, VE	1
Andrei, G; De Clercq, E; Dimas, K; Foscolos, GB; Fytas, G; Kolocouris, A; Kolocouris, N; Pannecouque, C; Snoeck, R; Stamatiou, G; Witvrouw, M; Zoidis, G	1
Alam, N; Hong, J; Im, KS; Jung, JH; Lee, CK; Li, F; Liu, Y; Wang, W	1
Chun, MW; Jeong, LS; Kim, HD; Kim, HO; Kim, JH; Kim, MJ	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Alvarez, K; Balzarini, J; Barral, K; Canard, B; Neyts, J; Priet, S; Sire, J	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Campillo, NE; Guerra, A; Páez, JA	1
Asaftei, S; De Clercq, E	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Geng, Y; Li, Y; Liu, Y; Qiao, W; Tan, J; Wang, L; Wang, M; Wang, Q; Wang, Z; Yao, X	2
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Çapan, G; Cihan-Üstündağ, G; Gürsoy, E; Naesens, L; Ulusoy-Güzeldemirci, N	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chizhov, AO; Geisman, AN; Khandazhinskaya, AL; Kochetkov, SN; Naesens, L; Novikov, MS; Ozerov, AA; Pannecouque, C; Seley-Radtke, KL; Valuev-Elliston, VT	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Caliò, R; Perno, CF	1
Balzarini, J	1
Fernandez-Larsson, R; Patterson, JL	1
Eble, JN; Hoffman, R; Ichikawa, S; Jayaram, HN; Nagai, M; Nakamura, H; Natsumeda, Y; Paulik, E; Weber, G; Zhen, WN	1
Crumpacker, C; Finberg, RW; Heagy, W; Lopez, PA	1
Bean, B	1
Hirsch, MS; Schooley, RT; Vogt, M	1
Chou, TC; Coleman, LA; Crumpacker, C; Furman, PA; Fyfe, JA; Hartshorn, KL; Hirsch, MS; Schooley, RT; Vogt, MW	1
Hirsch, MS; Kaplan, JC	2
Pomerantz, RJ; Schooley, RT	1
Bryson, YJ	1
Henin, Y; Marechal, V; Montagnier, L; Schwartz, O	1
Mitchell, WM; Montefiori, DC; Robinson, WE	1
Bozzette, SA; Connor, JD; Kennedy, C; McCutchan, JA; Richman, DD; Spector, SA; Straube, RG	1
Blumberg, EA	1
Agrawal, KC; Beckman, BS; Gogu, SR	1
Miller, JL	1
Bozzette, S; Fay, MT; Freeman, WR; Hardy, D; Wiley, CA	1
Broder, S; Yarchoan, R	1
Sandström, E	1
Marwick, C; Riesenberg, DE	1
Barnes, DM	1
De Clercq, E; Gil-Fernández, C	1
Cockerill, FR; Hermans, PE	1
Busi, C; Di Stefano, G; Fiume, L; Mattioli, A	1
Morris, DJ	1
Brun-Vezinet, F; Pépin, JM; Simon, F	1
Baba, M; Fujiwara, M; Ijichi, K; Konno, K; Machida, H; Mori, K; Morozumi, M; Shigeta, S; Yokota, T	1
Back, DJ; Hart, CA; Hoggard, PG; Phiboonbanakit, D; Sales, SD; Sim, SM	1
Bricaire, F	1
Cote, P; Gerin, JL; Hornbuckle, W; Korba, BE; Tennant, BC	1
Ray, SC; Sulkowski, MS; Thomas, DL	1
Perronne, C	1
Choi, BG; Hong, JH; Kwak, EY; Park, Y	1
Back, D; Borucki, MJ; Dieterich, D; Gries, JM; Hoggard, PG; Lissen, E; Rodriguez-Torres, M; Soriano, V; Sulkowski, M; Torriani, FJ; Wang, K	1
Abdel-Rahman, A; Awad, LF; El Ashry, el SH; Rashed, N; Rasheed, HA	1
Alvarez, D; Ball, L; Brau, N; Dieterich, DT; Moorehead, L; Sulkowski, MS	1
Bowers, P; Henry, DH; Lamarca, A; Leitz, G; Slim, J	1
Han, HY; Kohli, E; Vinogradov, SV; Zeman, AD	1
Alston, B; Aweeka, FT; Chung, RT; Kang, M; Lizak, P; Yu, JY	1
Bani-Sadr, F; Billaud, E; Cacoub, P; Carrat, F; Doll, J; Goderel, I; Penalba, C; Perronne, C; Pol, S; Welker, Y	1
Aguirrebengoa, K; Asensi, V; Barreiro, P; Cervantes, M; Echeverria, S; Garcia-Samaniego, J; Núñez, M; Ocampo, A; Pascual, A; Soriano, V	1
Arizcorreta-Yarza, A; Collado, A; Fernández-Fuertes, E; Girón-González, JA; González-Serrano, M; López-Cortés, LF; Lozano, F; Macías, J; Merino, D; Mira, JA; Pineda, JA; Ríos-Villegas, MJ; Rivero, A; Torres-Tortoso, M; Valera-Bestard, B	1
Andersen, JW; Butt, AA; Chung, RT; Sherman, KE; Umbleja, T	1
Moreno, V; Valencia, ME	1
Balzarini, J; Derudas, M; Grivel, JC; Introini, A; Lisco, A; Margolis, L; McGuigan, C; Merbah, M; Munawwar, A; Schinazi, RF; Vanpouille, C	1
Arends, J; Chene, G; Cosin, J; Dabis, F; Daikos, G; de Wit, S; Mallolas, J; Montforte, Ad; Mussini, C; Peters, L; Raben, D; Rockstroh, J; Smit, C; Zangerle, R; Zinkernagel, A	1
Callard, RE; Klein, NJ; Lewis, J; Majekodunmi, AO; Malyuta, R; Thorne, C; Volokha, A	1
Koloňuk, I; Lenz, O; Přibylová, J; Sedlák, J; Semerák, M; Špak, J	1

Reviews

13 review(s) available for ribavirin and zidovudine

Article	Year
Chemotherapeutic approaches to the treatment of the acquired immune deficiency syndrome (AIDS). Journal of medicinal chemistry, 1986, Volume: 29, Issue:9 Topics: Acquired Immunodeficiency Syndrome; Adsorption; Antibodies, Viral; Antigens, Viral; Aurintricarboxylic Acid; Deltaretrovirus; Deoxycytidine; Foscarnet; Genes, Viral; Glycoproteins; Humans; Interferons; Male; Phosphonoacetic Acid; Retroviridae Infections; Reverse Transcriptase Inhibitors; Ribavirin; RNA, Viral; Suramin; Thymidine; Transcription, Genetic; Viral Proteins; Virus Replication; Zalcitabine; Zidovudine	1986
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[New therapeutic trends in AIDS]. La Clinica terapeutica, 1992, Volume: 140, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Deoxyadenosines; Didanosine; Dideoxynucleosides; Humans; Poly I-C; Poly U; Randomized Controlled Trials as Topic; Ribavirin; RNA, Double-Stranded; Zalcitabine; Zidovudine	1992
Regulation of de novo and salvage pathways in chemotherapy. Advances in enzyme regulation, 1991, Volume: 31 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Humans; Leukemia; Pyrimidines; Ribavirin; Thymidine Kinase; Thymidylate Synthase; Zidovudine	1991
Therapy of human immunodeficiency virus infections. Clinics in laboratory medicine, 1987, Volume: 7, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Foscarnet; Humans; Immunotherapy; Interferons; Oligodeoxyribonucleotides; Phosphonoacetic Acid; Ribavirin; Suramin; Thymidine; Zidovudine	1987
Promising new antiviral drugs. Journal of the American Academy of Dermatology, 1988, Volume: 18, Issue:1 Pt 2 Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cytomegalovirus Infections; Foscarnet; Ganciclovir; Herpes Simplex; Herpes Zoster; Humans; Interferons; Phosphonoacetic Acid; Ribavirin; Thymidine; Zidovudine	1988
Antiviral therapy. American family physician, 1989, Volume: 39, Issue:2 Topics: Acyclovir; Antiviral Agents; Humans; Ribavirin; Vidarabine; Virus Diseases; Zidovudine	1989
Progress in the development of antiviral therapy for HTLV-III-associated diseases. Important advances in oncology, 1987 Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Foscarnet; HIV; Humans; Phosphonoacetic Acid; Ribavirin; Rifabutin; Rifamycins; Suramin; Thymidine; Tungsten; Tungsten Compounds; Zidovudine	1987
Antiviral drugs for AIDS. Current status and future prospects. Drugs, 1986, Volume: 31, Issue:6 Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Foscarnet; Humans; Interferon Type I; Phosphonoacetic Acid; Ribavirin; Suramin; Thymidine; Tungsten; Tungsten Compounds; Zidovudine	1986
Treatment of human immunodeficiency virus infections. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:6 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; HIV; Humans; Ribavirin; Thymidine; Zidovudine	1987
Adverse effects and drug interactions of clinical importance with antiviral drugs. Drug safety, 1994, Volume: 10, Issue:4 Topics: Acyclovir; AIDS-Related Opportunistic Infections; Amantadine; Antiviral Agents; Didanosine; Drug Interactions; Foscarnet; Ganciclovir; Humans; Interferon-alpha; Ribavirin; Rimantadine; Vidarabine; Zalcitabine; Zidovudine	1994
[Is resistance of human immunodeficiency viruses (HIV) to nucleoside analogs an indication for their combined use?]. Pathologie-biologie, 1993, Volume: 41, Issue:8 Pt 2 Topics: Acyclovir; Didanosine; Drug Synergism; Drug Therapy, Combination; Female; Foscarnet; HIV-1; Humans; In Vitro Techniques; Male; Ribavirin; Zalcitabine; Zidovudine	1993
[Treatment of chronic hepatitis C in patients coinfected with HIV: tolerability, drug interactions, therapeutic indications]. Gastroenterologie clinique et biologique, 2002, Volume: 26 Spec No 2 Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Didanosine; Drug Interactions; Hepatitis C, Chronic; HIV Infections; Humans; Interferon-alpha; Life Style; Mitochondria; Monitoring, Physiologic; Multicenter Studies as Topic; Patient Selection; Randomized Controlled Trials as Topic; Retrospective Studies; Reverse Transcriptase Inhibitors; Ribavirin; Stavudine; Time Factors; Viral Load; Zidovudine	2002

Trials

7 trial(s) available for ribavirin and zidovudine

Article	Year
[Chemotherapy and immunoprophylaxis of HIV infection]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1986, Nov-25, Volume: 75, Issue:48 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Foscarnet; HIV; Humans; Phosphonoacetic Acid; Reverse Transcriptase Inhibitors; Ribavirin; Suramin; Thymidine; Viral Vaccines; Virus Replication; Zidovudine	1986
The antiviral effect of zidovudine and ribavirin in clinical trials and the use of p24 antigen levels as a virologic marker. The Journal of infectious diseases, 1989, Volume: 159, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Clinical Trials as Topic; Double-Blind Method; HIV Antigens; HIV Core Protein p24; Humans; Male; Multicenter Studies as Topic; Random Allocation; Retroviridae Proteins; Ribavirin; Ribonucleosides; Zidovudine	1989
Progress in antiviral drug and vaccine development assessed at international AIDS conference. Clinical pharmacy, 1987, Volume: 6, Issue:8 Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Drug Evaluation; Drug Therapy, Combination; Humans; Ribavirin; Thymidine; Viral Vaccines; Zalcitabine; Zidovudine	1987
Effect of ribavirin on intracellular and plasma pharmacokinetics of nucleoside reverse transcriptase inhibitors in patients with human immunodeficiency virus-hepatitis C virus coinfection: results of a randomized clinical study. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:10 Topics: Adult; Area Under Curve; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C; HIV Infections; HIV-1; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Reverse Transcriptase Inhibitors; Ribavirin; Stavudine; Time Factors; Zidovudine	2005
Zidovudine use but not weight-based ribavirin dosing impacts anaemia during HCV treatment in HIV-infected persons. Journal of viral hepatitis, 2006, Volume: 13, Issue:10 Topics: Adult; Anemia; Antiviral Agents; Body Weight; Drug Therapy, Combination; Female; Hemoglobins; Hepatitis C, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Zidovudine	2006
Risk factors for anaemia in human immunodeficiency virus/hepatitis C virus-coinfected patients treated with interferon plus ribavirin. Journal of viral hepatitis, 2007, Volume: 14, Issue:9 Topics: Adult; Anemia; Anti-HIV Agents; Antiviral Agents; Drug Therapy, Combination; Female; Hepatitis C, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Kaplan-Meier Estimate; Male; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Risk Factors; Zidovudine	2007
Incidence of anaemia and impact on sustained virological response in HIV/HCV-coinfected patients treated with pegylated interferon plus ribavirin. Journal of viral hepatitis, 2008, Volume: 15, Issue:5 Topics: Adult; Anemia; Anti-HIV Agents; Antiviral Agents; Biomarkers; Drug Therapy, Combination; Female; Hemoglobins; Hepatitis C, Chronic; HIV Infections; Humans; Incidence; Interferon alpha-2; Interferon-alpha; Male; Multivariate Analysis; Polyethylene Glycols; Predictive Value of Tests; Prospective Studies; Recombinant Proteins; Ribavirin; Treatment Outcome; Withholding Treatment; Zidovudine	2008

Other Studies

60 other study(ies) available for ribavirin and zidovudine

Article	Year
Unsaturated and carbocyclic nucleoside analogues: synthesis, antitumor, and antiviral activity. Journal of medicinal chemistry, 1991, Volume: 34, Issue:1 Topics: Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Cell Line; Cell Survival; Drug Screening Assays, Antitumor; Friend murine leukemia virus; HIV-1; HIV-2; Humans; Indicators and Reagents; Leukemia L1210; Mice; Molecular Structure; Nucleosides; Rauscher Virus; Structure-Activity Relationship	1991
Stereospecific synthesis and antiviral properties of different enantiomerically pure carbocyclic 2'-deoxyribonucleoside analogues derived from common chiral pools: (+)-(1R,5S)- and (-)-(1S,5R)-2-oxabicyclo[3.3.0]oct-6-en-3-one. Journal of medicinal chemistry, 1990, Volume: 33, Issue:5 Topics: Antiviral Agents; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Chemical Phenomena; Chemistry; Microbial Sensitivity Tests; Simplexvirus; Stereoisomerism; Structure-Activity Relationship; Thymidine; Vaccinia virus	1990
Synthesis of acyclo-C-nucleosides in the imidazo[1,2-a]pyridine and pyrimidine series as antiviral agents. Journal of medicinal chemistry, 1996, Jul-05, Volume: 39, Issue:14 Topics: Animals; Antiviral Agents; Chlorocebus aethiops; HeLa Cells; Humans; Nucleosides; Pyridines; Pyrimidines; Structure-Activity Relationship; Tumor Cells, Cultured; Vero Cells	1996
Novel 3'-C/N-substituted 2',3'-beta-D-dideoxynucleosides as potential chemotherapeutic agents. 1. Thymidine derivatives: synthesis, structure, and broad spectrum antiviral properties. Journal of medicinal chemistry, 1997, Feb-14, Volume: 40, Issue:4 Topics: Antiviral Agents; Crystallography, X-Ray; Dideoxynucleosides; HIV-1; HIV-2; Humans; Isomerism; Models, Chemical; Models, Molecular; Structure-Activity Relationship; Thymidine; Virus Replication	1997
New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation. Bioorganic & medicinal chemistry letters, 2002, Mar-11, Volume: 12, Issue:5 Topics: Bacteria; Cell Division; Cell Line; Formazans; Humans; Hydrazones; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazolium Salts; Thiosemicarbazones; Tumor Cells, Cultured; Viruses	2002
New saponins from the starfish Certonardoa semiregularis. Journal of natural products, 2002, Volume: 65, Issue:11 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Artemia; HeLa Cells; Humans; Korea; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Saponins; Starfish; Stereoisomerism; Steroids	2002
Synthesis and biological evaluation of thymine nucleosides fused with 3',4'-tetrahydrofuran ring. Bioorganic & medicinal chemistry letters, 2003, Oct-20, Volume: 13, Issue:20 Topics: Cell Line; Furans; Microbial Sensitivity Tests; Thymine; Viruses	2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Synthesis, in vitro antiviral evaluation, and stability studies of novel alpha-borano-nucleotide analogues of 9-[2-(phosphonomethoxy)ethyl]adenine and (R)-9-[2-(phosphonomethoxy)propyl]adenine. Journal of medicinal chemistry, 2006, Dec-28, Volume: 49, Issue:26 Topics: Adenine; Animals; Anti-HIV Agents; Antiviral Agents; Boranes; Boron Compounds; Chlorocebus aethiops; DNA Viruses; HIV-1; Humans; In Vitro Techniques; Nucleosides; Organophosphonates; Phosphates; RNA Viruses; Structure-Activity Relationship; Vero Cells; Virus Replication	2006
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks. Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2 Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
"Viologen" dendrimers as antiviral agents: the effect of charge number and distance. Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Anti-HIV Agents; Antiviral Agents; Cell Line; Dendrimers; HIV; Humans; Static Electricity; Structure-Activity Relationship; Viologens	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Design, synthesis and antiviral activity of novel quinazolinones. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Antiviral Agents; Chemistry Techniques, Synthetic; Drug Design; HIV; Quinazolinones; Tobacco Mosaic Virus	2012
Design, synthesis and antiviral activity of novel pyridazines. European journal of medicinal chemistry, 2012, Volume: 54 Topics: Antiviral Agents; Chemistry Techniques, Synthetic; Drug Design; Drug Evaluation, Preclinical; HIV-1; Pyridazines; Structure-Activity Relationship; Tobacco Mosaic Virus	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Synthesis and antiviral properties of novel indole-based thiosemicarbazides and 4-thiazolidinones. Bioorganic & medicinal chemistry, 2016, Jan-15, Volume: 24, Issue:2 Topics: Animals; Antiviral Agents; Cats; Cells, Cultured; Chlorocebus aethiops; DNA Viruses; Dogs; Dose-Response Relationship, Drug; HeLa Cells; Humans; Indoles; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Molecular Structure; RNA Viruses; Semicarbazides; Structure-Activity Relationship; Thiazolidines; Vero Cells; Virus Replication	2016
1,6-Bis[(benzyloxy)methyl]uracil derivatives-Novel antivirals with activity against HIV-1 and influenza H1N1 virus. Bioorganic & medicinal chemistry, 2016, 06-01, Volume: 24, Issue:11 Topics: Animals; Antiviral Agents; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; HIV-1; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Uracil	2016
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
[Anti-retroviral activity and molecular-biochemical action mechanism of 2',3'-dideoxynucleoside analogs and 9-(2-phosphonylmethoxyethyl) purine derivatives]. Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1991, Volume: 53, Issue:1 Topics: Adenine; Antiviral Agents; Humans; Phosphorylation; Pyrimidine Nucleosides; Retroviridae; Ribavirin; Structure-Activity Relationship; Zalcitabine; Zidovudine	1991
Ribavirin is an inhibitor of human immunodeficiency virus reverse transcriptase. Molecular pharmacology, 1990, Volume: 38, Issue:6 Topics: Avian Myeloblastosis Virus; HIV-1; Kinetics; Reverse Transcriptase Inhibitors; Ribavirin; Zidovudine	1990
Inhibition of immune functions by antiviral drugs. The Journal of clinical investigation, 1991, Volume: 87, Issue:6 Topics: Acyclovir; Antiviral Agents; Cell Cycle; Cells, Cultured; Concanavalin A; Didanosine; DNA; Ganciclovir; Humans; Immunity; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Proteins; Ribavirin; Zidovudine	1991
Antiviral therapy. New drugs and their uses. Postgraduate medicine, 1986, Volume: 80, Issue:1 Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Amantadine; Antiviral Agents; Chickenpox; Common Cold; Cytomegalovirus Infections; Herpes Simplex; Herpes Zoster; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Influenza, Human; Interferons; Ribavirin; Rimantadine; Thymidine; Vidarabine; Virus Diseases; Zidovudine	1986
Ribavirin antagonizes the effect of azidothymidine on HIV replication. Science (New York, N.Y.), 1987, Mar-13, Volume: 235, Issue:4794 Topics: Cell Line; HIV; Humans; Lymphocytes; Monocytes; Phosphorylation; Phytohemagglutinins; Ribavirin; Ribonucleosides; RNA-Directed DNA Polymerase; Thymidine; Virus Replication; Zidovudine	1987
Antiviral therapy. Scientific American, 1987, Volume: 256, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; Cytomegalovirus; DNA, Viral; Drug Resistance, Microbial; Herpesvirus 3, Human; Herpesvirus 4, Human; HIV; Humans; Interferons; Nucleosides; Reverse Transcriptase Inhibitors; Ribavirin; RNA, Messenger; RNA, Viral; Simplexvirus; Thymidine; Virus Diseases; Virus Physiological Phenomena; Virus Replication; Zidovudine	1987
A rapid and simple colorimetric test for the study of anti-HIV agents. AIDS research and human retroviruses, 1988, Volume: 4, Issue:6 Topics: Antiviral Agents; Cell Line; Colorimetry; Cytopathogenic Effect, Viral; Formazans; HIV; Humans; Microbial Sensitivity Tests; Ribavirin; RNA-Directed DNA Polymerase; Tetrazolium Salts; Thiazoles; Virus Replication; Zidovudine	1988
In vitro evaluation of mismatched double-stranded RNA (ampligen) for combination therapy in the treatment of acquired immunodeficiency syndrome. AIDS research and human retroviruses, 1989, Volume: 5, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Alkaloids; Amphotericin B; Antiviral Agents; Drug Therapy, Combination; Foscarnet; HIV; Humans; In Vitro Techniques; Indolizines; Interferon beta-1a; Interferon beta-1b; Interferon Type I; Interferon-beta; Interferon-gamma; Interferons; Microbial Sensitivity Tests; Phosphonoacetic Acid; Recombinant Proteins; Ribavirin; RNA, Double-Stranded; Zidovudine	1989
Anti-HIV drugs: comparative toxicities in murine fetal liver and bone marrow erythroid progenitor cells. Life sciences, 1989, Volume: 45, Issue:4 Topics: Animals; Antiviral Agents; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Dideoxynucleosides; Fetus; Hematopoietic Stem Cells; HIV; Liver; Mice; Ribavirin; Zalcitabine; Zidovudine	1989
Atypical retinitis in patients with the acquired immunodeficiency syndrome. American journal of ophthalmology, 1988, May-15, Volume: 105, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Cytomegalovirus Infections; Fluorescein Angiography; Fundus Oculi; Humans; Male; Retinitis; Ribavirin; Thymidine; Zidovudine	1988
Anti-AIDS agents show varying early results in vitro and in vivo. JAMA, 1985, Nov-08, Volume: 254, Issue:18 Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Deltaretrovirus; Humans; Ribavirin; Suramin; Thymidine; Tungsten; Tungsten Compounds; Zidovudine	1985
In search of the best drugs against AIDS. Science (New York, N.Y.), 1986, Jul-25, Volume: 233, Issue:4762 Topics: Acquired Immunodeficiency Syndrome; Deltaretrovirus; Humans; Ribavirin; Suramin; Thymidine; Zidovudine	1986
Comparative efficacy of broad-spectrum antiviral agents as inhibitors of African swine fever virus replication in vitro. Antiviral research, 1987, Volume: 7, Issue:3 Topics: Adenine; African Swine Fever Virus; Amides; Animals; Antiviral Agents; Dose-Response Relationship, Drug; Iridoviridae; Organophosphonates; Organophosphorus Compounds; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Thymidine; Tubercidin; Vero Cells; Virus Replication; Zidovudine	1987
Antiviral agents. Mayo Clinic proceedings, 1987, Volume: 62, Issue:12 Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Amantadine; Antiviral Agents; Ganciclovir; Herpes Simplex; Humans; Idoxuridine; Influenza A virus; Influenza, Human; Ribavirin; Rimantadine; Thymidine; Vidarabine; Viruses; Zidovudine	1987
Selective delivery to the liver of antiviral nucleoside analogs coupled to a high molecular mass lactosaminated poly-L-lysine and administered to mice by intramuscular route. Biochemical pharmacology, 1995, Jun-16, Volume: 49, Issue:12 Topics: Amino Sugars; Animals; Carbon Radioisotopes; Drug Carriers; Female; Injections, Intramuscular; Liver; Mice; Molecular Weight; Polylysine; Rats; Rats, Wistar; Ribavirin; Vidarabine Phosphate; Zidovudine	1995
Antiviral activities of nucleotide heterodimers against human immunodeficiency virus type 1 in vitro. Antiviral research, 1996, Volume: 31, Issue:1-2 Topics: Anti-HIV Agents; Cell Line, Transformed; Cytopathogenic Effect, Viral; Didanosine; HIV-1; Humans; Ribavirin; Uracil; Zidovudine	1996
Effect of ribavirin on zidovudine efficacy and toxicity in vitro: a concentration-dependent interaction. AIDS research and human retroviruses, 1998, Dec-20, Volume: 14, Issue:18 Topics: Anti-HIV Agents; Antiviral Agents; Cell Line; Drug Synergism; Humans; Reverse Transcriptase Inhibitors; Ribavirin; Thymine Nucleotides; Zidovudine	1998
[Infectious diseases in 1998]. La Revue de medecine interne, 1999, Volume: 20, Issue:4 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-HIV Agents; Antiviral Agents; Bacterial Vaccines; Blood Donors; Clinical Trials as Topic; Drug Therapy, Combination; Hepatitis C; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Interferons; Lamivudine; Middle Aged; Multicenter Studies as Topic; Pneumonia, Pneumococcal; Randomized Controlled Trials as Topic; Ribavirin; Streptococcus pneumoniae; Transfusion Reaction; Zidovudine	1999
Treatment of chronic woodchuck hepatitis virus infection in the Eastern woodchuck (Marmota monax) with nucleoside analogues is predictive of therapy for chronic hepatitis B virus infection in humans. Hepatology (Baltimore, Md.), 2000, Volume: 31, Issue:5 Topics: 2-Aminopurine; Animals; Antiviral Agents; Famciclovir; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Humans; Marmota; Ribavirin; Vidarabine Phosphate; Virus Replication; Zidovudine	2000
Needlestick transmission of hepatitis C. JAMA, 2002, May-08, Volume: 287, Issue:18 Topics: Accidents, Occupational; Acute Disease; Adult; Anti-HIV Agents; Antiviral Agents; Asthenia; Exanthema; Hepacivirus; Hepatitis C; Hepatitis C Antibodies; HIV Infections; Humans; Infectious Disease Transmission, Patient-to-Professional; Interferon alpha-2; Interferon-alpha; Internship and Residency; Lamivudine; Needlestick Injuries; Nelfinavir; Occupational Exposure; Physicians; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Viremia; Zidovudine	2002
Synthesis and antiviral activity of novel C-methyl branched cyclopropyl nucleosides. Archives of pharmacal research, 2003, Volume: 26, Issue:9 Topics: Adenine; Antiviral Agents; Crystallography, X-Ray; Cyclization; Cyclopropanes; Cytomegalovirus; Cytotoxicity Tests, Immunologic; Ganciclovir; Herpesvirus 1, Human; HIV-1; Korea; Magnetic Resonance Spectroscopy; Methylation; Molecular Structure; Purine Nucleosides; Purines; Ribavirin; Zidovudine	2003
Synthesis of AZT analogues: 7-(3-azido-2-hydroxypropyl)-, 7-(3-amino-2-hydroxypropyl)-,7-(3-triazolyl-2-hydroxypropyl)theophylline. Nucleosides, nucleotides & nucleic acids, 2006, Volume: 25, Issue:3 Topics: Anti-HIV Agents; Ribavirin; Zidovudine	2006
Natural history of anemia associated with interferon/ribavirin therapy for patients with HIV/HCV coinfection. AIDS research and human retroviruses, 2007, Volume: 23, Issue:1 Topics: Adolescent; Adult; Aged; Anemia; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Black People; Cell Count; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythropoietin; Female; Hemoglobins; Hepatitis C, Chronic; Hispanic or Latino; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Protease Inhibitors; Recombinant Proteins; Reticulocytes; Retrospective Studies; Reverse Transcriptase Inhibitors; Ribavirin; Time Factors; Treatment Outcome; White People; Zidovudine	2007
Formulations of biodegradable Nanogel carriers with 5'-triphosphates of nucleoside analogs that display a reduced cytotoxicity and enhanced drug activity. Journal of controlled release : official journal of the Controlled Release Society, 2007, Aug-16, Volume: 121, Issue:1-2 Topics: Adenosine Triphosphate; Animals; Antiviral Agents; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Survival; Dideoxynucleotides; Dogs; Dose-Response Relationship, Drug; Drug Carriers; Female; Fluorescent Dyes; Formazans; Humans; Influenza A virus; Inhibitory Concentration 50; Kidney; L-Lactate Dehydrogenase; Luminescent Measurements; Membrane Potentials; Mitochondria; Nanogels; Nanotechnology; Polyethylene Glycols; Polyethyleneimine; Rhodamines; Ribavirin; Sensitivity and Specificity; Tetrazolium Salts; Thymine Nucleotides; Zidovudine	2007
Pharmacokinetic evaluation of the effects of ribavirin on zidovudine triphosphate formation: ACTG 5092s Study Team. HIV medicine, 2007, Volume: 8, Issue:5 Topics: Adult; Antiviral Agents; Area Under Curve; Drug Interactions; Hepacivirus; Hepatitis C, Chronic; HIV Infections; HIV-1; Humans; Middle Aged; Phosphorylation; Reverse Transcriptase Inhibitors; Ribavirin; Zidovudine	2007
Predictors of severe haematological toxicity secondary to pegylated interferon plus ribavirin treatment in HIV-HCV-coinfected patients. Antiviral therapy, 2007, Volume: 12, Issue:8 Topics: Adult; Anemia; Antiviral Agents; Biomarkers; Drug Therapy, Combination; Female; Fibrosis; Hepatitis C, Chronic; HIV; HIV Infections; Humans; Injections, Subcutaneous; Interferon alpha-2; Interferon-alpha; Leukocyte Count; Male; Neutropenia; Platelet Count; Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Ribavirin; Risk Factors; Spain; Thrombocytopenia; Zidovudine	2007
The incidence, predictors and management of anaemia and its association with virological response in HCV / HIV coinfected persons treated with long-term pegylated interferon alfa 2a and ribavirin. Alimentary pharmacology & therapeutics, 2011, Volume: 33, Issue:11 Topics: Adult; Anemia; Antiviral Agents; Drug Therapy, Combination; Female; Hepatitis C; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Multivariate Analysis; Patient Compliance; Polyethylene Glycols; Prospective Studies; Randomized Controlled Trials as Topic; Recombinant Proteins; Ribavirin; Risk Factors; Time Factors; Treatment Outcome; Zidovudine	2011
[Coinfection with HIV and HCV: abacavir and ribavirine, why not?]. Revista clinica espanola, 2012, Volume: 212, Issue:1 Topics: Anti-HIV Agents; Antiviral Agents; Coinfection; Dideoxynucleosides; Drug Combinations; Drug Interactions; Hepatitis C, Chronic; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Ribavirin; Zidovudine	2012
Exploiting the anti-HIV-1 activity of acyclovir: suppression of primary and drug-resistant HIV isolates and potentiation of the activity by ribavirin. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:5 Topics: Acyclovir; Anti-HIV Agents; Cell Line; Drug Resistance, Viral; Drug Synergism; HIV Fusion Inhibitors; HIV Infections; HIV-1; Humans; Lamivudine; Nevirapine; Palatine Tonsil; Protease Inhibitors; Ribavirin; T-Lymphocytes; Tissue Culture Techniques; Zidovudine	2012
Effect of abacavir on sustained virologic response to HCV treatment in HIV/HCV co-infected patients, Cohere in Eurocoord. BMC infectious diseases, 2015, Nov-04, Volume: 15 Topics: Adult; Anti-HIV Agents; Cohort Studies; Coinfection; Dideoxynucleosides; Drug Combinations; Emtricitabine; Europe; Female; Hepacivirus; Hepatitis C; HIV Infections; Humans; Interferon-alpha; Lamivudine; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Reverse Transcriptase Inhibitors; Ribavirin; Tenofovir; Zidovudine	2015
Modelling CD4 T Cell Recovery in Hepatitis C and HIV Co-infected Children Receiving Antiretroviral Therapy. The Pediatric infectious disease journal, 2017, Volume: 36, Issue:5 Topics: Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Child; Child, Preschool; Cohort Studies; Coinfection; Drug Combinations; Female; Hepacivirus; Hepatitis C; HIV Infections; HIV-1; Humans; Interferon-alpha; Lamivudine; Lopinavir; Male; Models, Immunological; Polyethylene Glycols; Recombinant Proteins; Recovery of Function; Ribavirin; Ritonavir; Time-to-Treatment; Zidovudine	2017
Elimination of Solanum nigrum ilarvirus 1 and Apple Hammerhead Viroid from Apple Cultivars Using Antivirals Ribavirin, Rimantadine, and Zidovudine. Viruses, 2023, 08-02, Volume: 15, Issue:8 Topics: Antiviral Agents; Ilarvirus; Malus; Ribavirin; Rimantadine; Solanum nigrum; Viroids; Zidovudine	2023