Page last updated: 2024-08-16

ribavirin and ribavirin 5'-triphosphate

ribavirin has been researched along with ribavirin 5'-triphosphate in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's0 (0.00)18.2507
2000's7 (38.89)29.6817
2010's6 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cameron, CE; Graci, JD; Moriyama, K; Negishi, K; Suzuki, T; Thompson, CN; Watanabe, M1
Cameron, CE; Oh, HS; Padmanabhan, R; Peterson, BR; Smidansky, ED; Takhampunya, R; Wu, R1
Fernandez-Larsson, R; Koumans, E; O'Connell, K; Patterson, JL1
O'Connell, K; Patterson, JL; Toltzis, P1
Gilbert, BE; Knight, V; Smith, RH; Wray, SK1
Gilbert, BE; Knight, V; Wray, SK1
Borek, E; Goswami, BB; Sharma, OK1
Andino, R; Arnold, JJ; Cameron, CE; Crotty, S; Hong, Z; Lau, JY; Maag, D; Zhong, W1
Borowski, P; Choe, J; Haag, A; Kulikowski, T; Lang, M; Niebuhr, A; Schmitz, H; Schulze zur Wiesch, J; Siwecka, MA1
Canard, B; Chen, Y; Deville-Bonne, D; Dutartre, H; Gallois-Montbrun, S; Guerreiro, C; Janin, J; Morera, S; Mulard, L; Schneider, B; Sophys, M; Veron, M1
Bisaillon, M; Bougie, I1
Chu, YK; Chung, DH; Jonsson, CB; Parker, WB; Sun, Y1
Meléndez, M; Rodríguez, JF; Rosario, O; Zayas, B1
Drexler, DM; Grace, JE; Wei, C; Zvyaga, TA1
Garvie, CW1
Anderson, PL; Bushman, LR; Jimmerson, LC; Kiser, JJ; Klein, B; Ray, ML; Rower, JE; Zheng, JH1
Clayton, CW; Jimmerson, LC; Kiser, JJ; Kottilil, S; MaWhinney, S; Meissner, EG; Sims, Z1
Adamek, L; Brunet, S; Hellstrand, K; Lagging, M; Nilsson, S; Norder, H; Nyström, K; Said, J; Tang, KW; Waldenström, J; Wanrooij, PH; Wind-Rotolo, M1

Other Studies

18 other study(ies) available for ribavirin and ribavirin 5'-triphosphate

ArticleYear
Effects of introduction of hydrophobic group on ribavirin base on mutation induction and anti-RNA viral activity.
    Journal of medicinal chemistry, 2008, Jan-10, Volume: 51, Issue:1

    Topics: Amides; Antiviral Agents; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Mutation; Organophosphates; Poliovirus; Ribavirin; RNA-Dependent RNA Polymerase; RNA, Viral; Structure-Activity Relationship

2008
Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses.
    Journal of medicinal chemistry, 2010, Nov-25, Volume: 53, Issue:22

    Topics: Adenosine; Antiviral Agents; Cell Line; Dengue Virus; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Poliovirus; Purine Nucleosides; Structure-Activity Relationship; Virology; Virus Replication

2010
Molecular analysis of the inhibitory effect of phosphorylated ribavirin on the vesicular stomatitis virus in vitro polymerase reaction.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:10

    Topics: Antiviral Agents; DNA-Directed RNA Polymerases; Genes, Viral; Kinetics; Nucleotides; Ribavirin; Ribonucleosides; Transcription, Genetic; Vesicular stomatitis Indiana virus

1989
Effect of phosphorylated ribavirin on vesicular stomatitis virus transcription.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:4

    Topics: Nucleotides; Ribavirin; Ribonucleosides; RNA, Viral; Transcription, Genetic; Vesicular stomatitis Indiana virus

1988
Effects of selenazofurin and ribavirin and their 5'-triphosphates on replicative functions of influenza A and B viruses.
    Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:1

    Topics: Animals; Cells, Cultured; DNA-Directed RNA Polymerases; Dogs; Influenza A virus; Influenza B virus; Nucleotides; Organoselenium Compounds; Ribavirin; Ribonucleosides; Ribonucleotides; Selenium; Virus Replication

1986
Effect of ribavirin triphosphate on primer generation and elongation during influenza virus transcription in vitro.
    Antiviral research, 1985, Volume: 5, Issue:1

    Topics: Antiviral Agents; DNA-Directed RNA Polymerases; Nucleotides; Orthomyxoviridae; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Ribavirin; Ribonucleosides; Transcription, Genetic

1985
An approach to inhibition of viral replication: inhibition of mRNA methylation.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 84

    Topics: Kinetics; Methylation; Nucleotides; Nucleotidyltransferases; Oligoribonucleotides; Ribavirin; Ribonucleosides; RNA, Messenger; Vaccinia virus; Virus Replication

1983
The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen.
    Nature medicine, 2000, Volume: 6, Issue:12

    Topics: Antiviral Agents; DNA-Directed RNA Polymerases; Mutagens; Nucleotides; Poliovirus; Protein Biosynthesis; Ribavirin; RNA Viruses; RNA-Dependent RNA Polymerase; Virus Replication

2000
Inhibition of the helicase activity of HCV NTPase/helicase by 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide-5 '-triphosphate (ribavirin-TP).
    Acta biochimica Polonica, 2001, Volume: 48, Issue:3

    Topics: Acid Anhydride Hydrolases; Antiviral Agents; DNA; DNA Helicases; Hepacivirus; Kinetics; Nucleoside-Triphosphatase; Nucleotides; Ribavirin; Substrate Specificity

2001
Structural analysis of the activation of ribavirin analogs by NDP kinase: comparison with other ribavirin targets.
    Molecular pharmacology, 2003, Volume: 63, Issue:3

    Topics: Binding, Competitive; Catalytic Domain; Crystallography, X-Ray; DNA-Directed RNA Polymerases; Humans; Nucleic Acid Synthesis Inhibitors; Nucleoside-Diphosphate Kinase; Nucleotides; Protein Conformation; Ribavirin

2003
Initial binding of the broad spectrum antiviral nucleoside ribavirin to the hepatitis C virus RNA polymerase.
    The Journal of biological chemistry, 2003, Dec-26, Volume: 278, Issue:52

    Topics: Adenosine Triphosphate; Binding Sites; Binding, Competitive; Catalysis; Circular Dichroism; DNA-Directed RNA Polymerases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Guanidine; Hepacivirus; Interferon-alpha; Ions; Kinetics; Ligands; Nucleotides; Phosphorylation; Protein Binding; Ribavirin; Spectrometry, Fluorescence; Spectrophotometry; Thermodynamics; Time Factors

2003
Activity of ribavirin against Hantaan virus correlates with production of ribavirin-5'-triphosphate, not with inhibition of IMP dehydrogenase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Guanosine; Guanosine Triphosphate; Hantaan virus; IMP Dehydrogenase; Mycophenolic Acid; Nucleotides; Ribavirin; RNA, Viral; Time Factors; Vero Cells; Virus Replication

2007
HPLC-MS/MS method for the intracellular determination of ribavirin monophosphate and ribavirin triphosphate in CEM ss cells.
    Journal of pharmaceutical and biomedical analysis, 2009, Jul-12, Volume: 49, Issue:5

    Topics: Antiviral Agents; Calibration; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drug Stability; Freezing; Humans; Molecular Structure; Nucleotides; Quality Control; Reference Standards; Reproducibility of Results; Ribavirin; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors

2009
Utility of high-resolution accurate MS to eliminate interferences in the bioanalysis of ribavirin and its phosphate metabolites.
    Bioanalysis, 2012, Volume: 4, Issue:15

    Topics: Adenosine Monophosphate; Antiviral Agents; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Glucuronosyltransferase; Hepatitis C, Chronic; Humans; Nucleotides; Ribavirin; Spectrometry, Mass, Electrospray Ionization; Uridine; Uridine Diphosphate; Uridine Monophosphate

2012
Solution-based approach to study binding to the eIF4E cap-binding site using CD spectroscopy.
    Analytical biochemistry, 2013, Mar-01, Volume: 434, Issue:1

    Topics: Binding Sites; Circular Dichroism; Eukaryotic Initiation Factor-4E; Guanosine Diphosphate; Nucleotides; Protein Binding; Protein Refolding; Protein Structure, Tertiary; Recombinant Proteins; Ribavirin; RNA Cap Analogs; RNA Caps; Solutions

2013
Measurement of intracellular ribavirin mono-, di- and triphosphate using solid phase extraction and LC-MS/MS quantification.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015, Jan-26, Volume: 978-979

    Topics: Chromatography, Liquid; Dried Blood Spot Testing; Erythrocytes; Humans; Intracellular Space; Leukocytes, Mononuclear; Linear Models; Nucleotides; Reproducibility of Results; Ribavirin; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry

2015
Effects of ribavirin/sofosbuvir treatment and ITPA phenotype on endogenous purines.
    Antiviral research, 2017, Volume: 138

    Topics: Adenosine Triphosphate; Anemia, Hemolytic; Female; Guanosine Triphosphate; Hepatitis C, Chronic; Humans; Inosine Triphosphatase; Inosine Triphosphate; Male; Middle Aged; Nucleotides; Phenotype; Polymorphism, Single Nucleotide; Purines; Pyrophosphatases; Retrospective Studies; Ribavirin; Sofosbuvir

2017
Inosine Triphosphate Pyrophosphatase Dephosphorylates Ribavirin Triphosphate and Reduced Enzymatic Activity Potentiates Mutagenesis in Hepatitis C Virus.
    Journal of virology, 2018, 10-01, Volume: 92, Issue:19

    Topics: Antiviral Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Gene Expression Regulation; Guanosine Triphosphate; Hepacivirus; Hepatitis B Core Antigens; Hepatocytes; High-Throughput Nucleotide Sequencing; Host-Pathogen Interactions; Humans; Mutagenesis; Nucleotides; Pyrophosphatases; Ribavirin; RNA, Small Interfering; RNA, Viral; Signal Transduction

2018