Page last updated: 2024-08-16

ribavirin and pyrazines

ribavirin has been researched along with pyrazines in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (3.17)	29.6817
2010's	31 (49.21)	24.3611
2020's	30 (47.62)	2.80

Authors

Authors	Studies
Bailey, KW; Furuta, Y; Gowen, BB; Jung, KH; Mendenhall, M; Sanders, AB; Sidwell, RW; Wong, MH	1
Bailey, KW; Furuta, Y; Gowen, BB; Hall, JO; Jung, KH; Morrey, JD; Smee, DF; Stevens, JR; Wong, MH	1
Furuta, Y; Kawaoka, Y; Kiso, M; Le, QM; Ozawa, M; Sakabe, S; Sakai-Tagawa, Y; Shinya, K; Takahashi, K	1
de la Torre, JC; Freiberg, AN; Furuta, Y; Gowen, BB; Holbrook, MR; Juelich, T; Mendenhall, M; Messina, EL; Nunberg, JH; Russell, A; Smee, DF	1
Deval, J; Jin, Z; Kim, B; Rajwanshi, VK; Smith, LK	1
Bernreuther, C; de Lamballerie, X; Emmerich, P; Günther, S; Krasemann, S; Lehmann, M; Neumann, M; Oestereich, L; Ölschläger, S; Rieger, T; Wurr, S	1
Arias, A; Goodfellow, I; Thorne, L	1
Feldmann, H; Furuta, Y; Geisbert, J; Geisbert, TW; Gowen, BB; Komeno, T; Martellaro, C; Okumura, A; Rosenke, K; Safronetz, D; Saturday, G; Westover, JB	1
Bockholt, S; Günther, S; Krasemann, S; Lüdtke, A; Muñoz-Fontela, C; Oestereich, L; Pallasch, E; Rieger, T; Ruibal, P; Wurr, S	1
Bailey, KW; Bray, M; Dagley, A; Downs, B; Furuta, Y; Gowen, BB; Jung, KH; Sefing, EJ; Smee, DF; Van Wettere, AJ; Wandersee, L; Westover, JB	1
Andrei, G; Gillemot, S; Lemey, P; Naesens, L; Rajwanshi, VK; Van Houdt, J; Vanderlinden, E; Vrancken, B	1
Cameron, CE; Ciota, AT; Gohara, DW; Griesemer, SB; Kramer, LD; Pata, JD; Van Slyke, GA	1
Baz, M; Boivin, G; Goyette, N; Griffin, BD; Kobinger, GP	1
Akondy, RS; Cannon, D; Ellebedy, AH; Harmon, JR; Klena, JD; Kraft, CS; Lyon, MG; McElroy, AK; Mehta, AK; Nichol, ST; Ribner, BS; Sette, A; Sidney, J; Spiropoulou, CF; Varkey, JB	1
Carrillo-Bustamante, P; Graw, F; Guedj, J; Günther, S; Nguyen, THT; Oestereich, L	1
Becker, S; Brown, S; De Leuw, P; Eickmann, M; Faber, K; Kann, G; Klena, JD; Kraft, CS; Lyon, GM; McElroy, A; Mehta, AK; Morales, A; Nichol, S; Patel, K; Raabe, VN; Rabenau, H; Ribner, BS; Rollin, PE; Schuettfort, G; Stephan, C; Strecker, T; Ströher, U; Vanairsdale, S; Varkey, JB; Wolf, T	1
Bergeron, É; Chatterjee, P; Flint, M; Nichol, ST; Scholte, FEM; Spiropoulou, CF; Welch, SR	1
Arima, N; Baba, M; Okamoto, M; Saijo, M; Sakakibara, N; Toyama, M	1
Brown, AN; Bulitta, JB; Kim, TH; Pires de Mello, CP; Pomeroy, JJ; Rodriquez, JL; Tao, X	1
Ippolito, G; Nicastri, E; Vairo, F	1
Drenzek, C; Kraft, CS; O'Neal, JP; Raabe, V	1
Han, M; Huang, W; Li, X; Wu, X; Yu, F; Zhao, X	1
Kim, JA; Kumar, M; Seong, RK; Shin, OS	1
Bakonyi, T; Forgách, P; Gyuranecz, M; Marosi, A; Sulyok, KM	1
Emmott, E; Goodfellow, I; Jalal, H; Smielewska, A	1
Koraka, P; Kycko, A; Marzec, A; Orłowska, A; Osterhaus, ADME; Reichert, M; Smreczak, M; Trębas, P; Żmudziński, JF	1
Furuta, Y; Gowen, BB; Hickerson, BT; Jung, KH; Komeno, T; Westover, JB	1
Arias, A; Bassi, MR; Meyn, P; Polacek, C; Sempere, RN	1
Feldmann, H; Furuta, Y; Gowen, BB; Haddock, E; Hanley, PW; Hawman, DW; Komeno, T; Meade-White, K; Rosenke, K; Williamson, B	1
Domingo, E; Esteban, JI; Gallego, I; García-Álvarez, M; García-Crespo, C; Gómez, J; Gómez-González, A; Gregori, J; Perales, C; Quer, J; Soria, ME; Valiergue, R	1
Domingo, E; Esteban, JI; Gallego, I; Gregori, J; Guerrero-Murillo, M; Perales, C; Quer, J; Soria, ME	1
Arias, A; Sempere, RN	1
Brocato, RL; Hooper, JW	1
Honkimaa, A; Hyöty, H; Sioofy-Khojine, AB	1
Dudley, H; Janowski, AB; Wang, D	1
Barron, S; Barrot, L; Carbonnelle, C; de Lamballerie, X; Duthey, A; Guedj, J; Jacquot, F; Lacarelle, B; Madelain, V; Mentré, F; Mundweiler, S; Raoul, H; Solas, C; Thomas, D; Vallvé, A	1
Chan, MCW; Chen, D; Cheung, PP; Choy, KT; Chu, DKW; Huang, X; Hui, KPY; Kaewpreedee, P; Peiris, M; Sia, SF; Wong, AY; Yen, HL	1
Claus, M; Dauby, N; Dechamps, P; Gérard, M; Günther, S; Konopnicki, D; Mahieu, R; Malvy, D; Martin, C; Martiny, D; Morales, MA; Nasreddine, R; Perandones, C; Roman, A; Schuldt, G; Stevens, E; Swaan, C; Van den Wijngaert, S; Van Praet, S; Vandenberg, O; Veliziotis, I; Vlieghe, E	1
Cutrell, JB; Jodlowski, TZ; Monogue, ML; Sanders, JM	1
Chen, K; Couban, RJ; Du, X; Gong, X; Guyatt, G; He, N; Ibrahim, QI; Li, X; Li, Y; Liu, F; Liu, J; Liu, W; Shen, N; Tang, Q; Wu, Z; Xu, X; Ye, Z; Ying, Y; Zhai, S; Zhang, Q; Zhang, Y; Zhou, P	1
Bailey-Elkin, BA; Götte, M; Mark, BL; Tchesnokov, EP	1
Chen, D; Dong, L; Pan, X; Peng, C; Yang, L	1
Li, C; Ren, L; Wang, L	1
Martinez, MA	1
Li, Z; Liu, Y; Wang, D	1
Carvalho Junior, RN; J C Neto, AM; Martins, AY; Reis, AF; S Costa, JF; Silva Arouche, TD	1
Li, Y; Miao, Z; Pan, Q; Peppelenbosch, MP; Wang, Y; Yu, P	1
Chishiki, M; Hashimoto, K; Hosoya, M; Kume, Y; Maeda, H; Maeda, R; Miyazaki, K; Norito, S; Ono, T; Sato, M; Suyama, K; Watanabe, M	1
Fätkenheuer, G; Malin, JJ; Rybniker, J; Simonis, A; Theobald, SJ	1
Abed, Y; Baz, M; Boivin, G; Checkmahomed, L; Padey, B; Pizzorno, A; Rosa-Calatrava, M; Terrier, O	1
Govil, A; Luckett, K; Miller-Handley, H	1
Guedj, J; Lingas, G; Rosenke, K; Safronetz, D	1
Wen, S; Xu, X; Yadav, AK; Yu, L	1
Danduga, RCSR; James, RA; Kandaswamy, DK; Raj, CTD; Rajasabapathy, R	1
Celik, I; Duzgun, Z; Erol, M	1
Aliota, MT; Bonnac, LF; Geraghty, RJ	1
A AlShahrani, S; A Enani, M; A Malhani, A; Halwani, R; R Alghareeb, M; Saheb Sharif-Askari, F; T Bin-Brikan, R; Tleyjeh, IM	1
Ami, Y; Doan, YH; Li, TC; Muramatsu, M; Suzaki, Y; Takeda, N; Zhang, W	1
Assis, LC; da Cunha, EFF; de Almeida La Porta, F; de Castro Ramalho, T; de Castro, AA; de Jesus, JPA; Kuca, K; Nepovimova, E	1
Hughes, C; Lewis, P; Warren, S; Waters, MD; Zhang, F	1
Kanda, T; Moriyama, M; Okamoto, H; Sasaki-Tanaka, R; Shibata, T	1
Egawa, K; Fujii, H; Fukushi, S; Furuta, Y; Harada, S; Komeno, T; Kurosu, T; Lim, CK; Maeki, T; Morikawa, S; Nakajima, N; Saijo, M; Shimojima, M; Takayama-Ito, M; Tani, H; Taniguchi, S; Uda, A; Yamada, S; Yoshikawa, T	1
Bergeron, E; Li, J; Ren, N; Wang, F; Wang, J; Wang, S; Xia, H; Yuan, Z; Zhang, B; Zhang, G; Zhao, L	1

Reviews

13 review(s) available for ribavirin and pyrazines

Article	Year
Progress on the Prevention and Treatment of Hantavirus Disease. Viruses, 2019, 07-04, Volume: 11, Issue:7 Topics: Adrenal Cortex Hormones; Amides; Animals; Antiviral Agents; Clinical Trials as Topic; Hantavirus Infections; Hantavirus Pulmonary Syndrome; Hemorrhagic Fever with Renal Syndrome; Humans; Immunotherapy; Lactoferrin; Models, Animal; Nucleosides; Orthohantavirus; Piperidines; Pyrazines; Quinazolines; Recombinant Proteins; Ribavirin; Triazoles; Vaccines, Synthetic; Viral Vaccines	2019
Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review. JAMA, 2020, May-12, Volume: 323, Issue:18 Topics: Adenosine Monophosphate; Adrenal Cortex Hormones; Alanine; Amides; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Immunoglobulins; Immunologic Factors; Indoles; Lopinavir; Oseltamivir; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2; Withholding Treatment	2020
Efficacy and safety of antiviral treatment for COVID-19 from evidence in studies of SARS-CoV-2 and other acute viral infections: a systematic review and meta-analysis. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2020, 07-06, Volume: 192, Issue:27 Topics: Amides; Antiviral Agents; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Evidence-Based Medicine; Humans; Hydroxychloroquine; Indoles; Influenza, Human; Lopinavir; Observational Studies as Topic; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2	2020
Potential drugs for the treatment of the novel coronavirus pneumonia (COVID-19) in China. Virus research, 2020, Volume: 286 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; China; Chloroquine; Coronavirus Infections; COVID-19; Drug Combinations; Drugs, Chinese Herbal; Humans; Indoles; Interferons; Lopinavir; Lung; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2; Survival Analysis	2020
Antiviral mechanisms of candidate chemical medicines and traditional Chinese medicines for SARS-CoV-2 infection. Virus research, 2020, Volume: 286 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; China; Coronavirus Infections; COVID-19; Drug Combinations; Drugs, Chinese Herbal; Humans; Hydroxychloroquine; Indoles; Interferons; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2; Survival Analysis; Teicoplanin	2020
Clinical Trials of Repurposed Antivirals for SARS-CoV-2. Antimicrobial agents and chemotherapy, 2020, 08-20, Volume: 64, Issue:9 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Drug Administration Schedule; Drug Combinations; Drug Repositioning; Humans; Hydroxychloroquine; Interferons; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Randomized Controlled Trials as Topic; Ribavirin; Ritonavir; SARS-CoV-2; Survival Analysis; Treatment Outcome	2020
An overview of the safety, clinical application and antiviral research of the COVID-19 therapeutics. Journal of infection and public health, 2020, Volume: 13, Issue:10 Topics: Adenosine Monophosphate; Alanine; Amides; Angiotensin-Converting Enzyme Inhibitors; Antimalarials; Antiviral Agents; Betacoronavirus; Biomedical Research; Coronavirus Infections; COVID-19; COVID-19 Serotherapy; Drug Combinations; Drug Development; Drugs, Chinese Herbal; Humans; Hydroxychloroquine; Immunization, Passive; Indoles; Interferons; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2	2020
A comparative analysis of remdesivir and other repurposed antivirals against SARS-CoV-2. EMBO molecular medicine, 2021, 01-11, Volume: 13, Issue:1 Topics: Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Benzamidines; COVID-19 Drug Treatment; Drug Repositioning; Esters; Guanidines; Guanine; Humans; Indoles; Lopinavir; Protease Inhibitors; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2; Virus Internalization; Virus Replication	2021
Treatment Options for Coronavirus Disease 2019 in Patients With Reduced or Absent Kidney Function. Advances in chronic kidney disease, 2020, Volume: 27, Issue:5 Topics: Adenosine Monophosphate; Alanine; Amides; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antiviral Agents; Chloroquine; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; COVID-19 Vaccines; Creatinine; Cytidine; Dexamethasone; Drug Combinations; Drug Interactions; Humans; Hydroxychloroquine; Hydroxylamines; Immunization, Passive; Interferons; Janus Kinase Inhibitors; Lopinavir; Pyrazines; Renal Elimination; Renal Insufficiency, Chronic; Renal Replacement Therapy; Ribavirin; Ritonavir; SARS-CoV-2	2020
Antiviral treatment in COVID-19: which is the most promising?-a narrative review. Annals of palliative medicine, 2021, Volume: 10, Issue:1 Topics: Adenosine Monophosphate; Alanine; Amides; Antibodies, Monoclonal, Humanized; Antiviral Agents; Azetidines; Chloroquine; COVID-19; COVID-19 Serotherapy; Drug Combinations; Humans; Hydroxychloroquine; Immunization, Passive; Indoles; Interferons; Ivermectin; Lopinavir; Nitro Compounds; Oseltamivir; Purines; Pyrazines; Pyrazoles; Ribavirin; Ritonavir; Sulfonamides; Thiazoles	2021
COVID-19: molecular pathophysiology, genetic evolution and prospective therapeutics-a review. Archives of microbiology, 2021, Volume: 203, Issue:5 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antiviral Agents; Chloroquine; COVID-19; COVID-19 Serotherapy; Dexamethasone; Drug Repositioning; Evolution, Molecular; Humans; Hydroxychloroquine; Immunization, Passive; Lopinavir; Pandemics; Phylogeny; Prospective Studies; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2	2021
Broad-Spectrum Antiviral Strategies and Nucleoside Analogues. Viruses, 2021, 04-13, Volume: 13, Issue:4 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antiviral Agents; COVID-19 Drug Treatment; Hemorrhagic Fever, Ebola; Humans; Middle East Respiratory Syndrome Coronavirus; Mutagenesis; Nucleosides; Pyrazines; Ribavirin; SARS-CoV-2; Virus Replication; Zika Virus; Zika Virus Infection	2021
Human genetic risk of treatment with antiviral nucleoside analog drugs that induce lethal mutagenesis: The special case of molnupiravir. Environmental and molecular mutagenesis, 2022, Volume: 63, Issue:1 Topics: Amides; Antiviral Agents; COVID-19 Drug Treatment; Cytidine; Deoxyuridine; DNA Damage; Genome, Human; Humans; Hydroxylamines; Mutagenesis; Nucleosides; Pyrazines; Ribavirin; SARS-CoV-2	2022

Other Studies

50 other study(ies) available for ribavirin and pyrazines

Article	Year
In vitro and in vivo activities of T-705 against arenavirus and bunyavirus infections. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9 Topics: Amides; Animals; Antiviral Agents; Arenaviridae Infections; Bunyaviridae Infections; Cell Line; Cricetinae; Haplorhini; Liver; Mice; Pyrazines; Ribavirin; Viral Load	2007
Treatment of late stage disease in a model of arenaviral hemorrhagic fever: T-705 efficacy and reduced toxicity suggests an alternative to ribavirin. PloS one, 2008, Volume: 3, Issue:11 Topics: Absorption; Administration, Oral; Alanine Transaminase; Amides; Animals; Arenaviridae Infections; Aspartate Aminotransferases; Cricetinae; Disease Models, Animal; Disease Progression; Female; Hemorrhagic Fevers, Viral; Interferon Type I; Liver Diseases; Mesocricetus; Pichinde virus; Pyrazines; Ribavirin; Survival Analysis; Treatment Outcome; Viral Load	2008
T-705 (favipiravir) activity against lethal H5N1 influenza A viruses. Proceedings of the National Academy of Sciences of the United States of America, 2010, Jan-12, Volume: 107, Issue:2 Topics: Aged; Amides; Animals; Antiviral Agents; Cell Line; Child; DNA Replication; DNA-Directed DNA Polymerase; Dogs; Drug Resistance, Viral; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Kidney; Kinetics; Lung; Oseltamivir; Pyrazines; Ribavirin	2010
T-705 (favipiravir) inhibition of arenavirus replication in cell culture. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:2 Topics: Amides; Animals; Antiviral Agents; Arenaviruses, New World; Cell Line; Chlorocebus aethiops; Humans; Junin virus; Lymphocytic choriomeningitis virus; Microbial Sensitivity Tests; Pyrazines; Ribavirin; Vero Cells; Virus Replication	2011
The ambiguous base-pairing and high substrate efficiency of T-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase. PloS one, 2013, Volume: 8, Issue:7 Topics: Amides; Animals; Antimetabolites; Antiviral Agents; Base Pair Mismatch; Base Pairing; DNA-Directed DNA Polymerase; Humans; Influenza A virus; Polyphosphates; Pyrazines; Ribavirin; Sf9 Cells; Spodoptera; Substrate Specificity	2013
Evaluation of antiviral efficacy of ribavirin, arbidol, and T-705 (favipiravir) in a mouse model for Crimean-Congo hemorrhagic fever. PLoS neglected tropical diseases, 2014, Volume: 8, Issue:5 Topics: Amides; Animals; Antiviral Agents; Chlorocebus aethiops; Disease Models, Animal; Female; Hemorrhagic Fever Virus, Crimean-Congo; Hemorrhagic Fever, Crimean; Indoles; Liver; Male; Mice; Mice, Transgenic; Pyrazines; Receptor, Interferon alpha-beta; Ribavirin; Vero Cells	2014
Favipiravir elicits antiviral mutagenesis during virus replication in vivo. eLife, 2014, Oct-21, Volume: 3 Topics: Amides; Animals; Antiviral Agents; Caliciviridae Infections; Cells, Cultured; Feces; Male; Mice, Inbred C57BL; Mutagenesis; Mutation Rate; Norovirus; Pyrazines; Ribavirin; RNA, Viral; Serial Passage; Virus Replication	2014
The broad-spectrum antiviral favipiravir protects guinea pigs from lethal Lassa virus infection post-disease onset. Scientific reports, 2015, Oct-12, Volume: 5 Topics: Amides; Animals; Animals, Outbred Strains; Antibodies, Viral; Antiviral Agents; Drug Administration Schedule; Drug Dosage Calculations; Guinea Pigs; Humans; Immunoglobulin G; Lassa Fever; Lassa virus; Liver; Lung; Male; Pyrazines; Ribavirin; Spleen; Survival Analysis; Viral Load	2015
Efficacy of Favipiravir Alone and in Combination With Ribavirin in a Lethal, Immunocompetent Mouse Model of Lassa Fever. The Journal of infectious diseases, 2016, Mar-15, Volume: 213, Issue:6 Topics: Amides; Animals; Antiviral Agents; Chlorocebus aethiops; Drug Therapy, Combination; Lassa Fever; Mice; Pyrazines; Ribavirin; Vero Cells; Viral Load; Virus Replication	2016
Low-dose ribavirin potentiates the antiviral activity of favipiravir against hemorrhagic fever viruses. Antiviral research, 2016, Volume: 126 Topics: Amides; Animals; Antiviral Agents; Arenavirus; Chlorocebus aethiops; Cricetinae; Dengue Virus; Disease Models, Animal; Drug Synergism; Female; Guinea Pigs; Hemorrhagic Fever Virus, Crimean-Congo; Hemorrhagic Fever, American; Hemorrhagic Fever, Ebola; Hemorrhagic Fevers, Viral; Junin virus; Male; Mesocricetus; Mice; Orthohantavirus; Pyrazines; Ribavirin; RNA Viruses; Vero Cells	2016
Distinct Effects of T-705 (Favipiravir) and Ribavirin on Influenza Virus Replication and Viral RNA Synthesis. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:11 Topics: A549 Cells; Amides; Animals; Antiviral Agents; Chick Embryo; DNA-Directed RNA Polymerases; Dogs; Gene Expression Regulation, Viral; Humans; IMP Dehydrogenase; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Madin Darby Canine Kidney Cells; Mutation; Pyrazines; Reassortant Viruses; Ribavirin; RNA, Viral; Sequence Analysis, RNA; Structure-Activity Relationship; Viral Proteins; Virus Replication	2016
Mutagen resistance and mutation restriction of St. Louis encephalitis virus. The Journal of general virology, 2017, Volume: 98, Issue:2 Topics: Amino Acid Substitution; Antiviral Agents; Drug Resistance, Viral; Encephalitis Virus, St. Louis; Encephalitis, St. Louis; Glutamic Acid; HeLa Cells; Humans; Lysine; Models, Molecular; Mutagens; Mutation; Nucleosides; Protein Domains; Pyrazines; Ribavirin; RNA-Dependent RNA Polymerase; Viral Nonstructural Proteins	2017
In vitro susceptibility of geographically and temporally distinct Zika viruses to favipiravir and ribavirin. Antiviral therapy, 2017, Volume: 22, Issue:7 Topics: Amides; Animals; Antiviral Agents; Chlorocebus aethiops; Drug Synergism; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Pyrazines; Ribavirin; Spatio-Temporal Analysis; Vero Cells; Zika Virus; Zika Virus Infection	2017
A Case of Human Lassa Virus Infection With Robust Acute T-Cell Activation and Long-Term Virus-Specific T-Cell Responses. The Journal of infectious diseases, 2017, 06-15, Volume: 215, Issue:12 Topics: Adult; Amides; Antibodies, Viral; Antigens, Viral; Antiviral Agents; CD8-Positive T-Lymphocytes; Enzyme-Linked Immunosorbent Assay; Humans; Immunity, Cellular; Immunoglobulin Class Switching; Lassa Fever; Lassa virus; Lymphocyte Activation; Male; Pyrazines; Ribavirin; Viremia	2017
Determining Ribavirin's mechanism of action against Lassa virus infection. Scientific reports, 2017, 09-15, Volume: 7, Issue:1 Topics: Amides; Animals; Antiviral Agents; Disease Models, Animal; Drug Therapy, Combination; Lassa Fever; Lassa virus; Mice, Inbred C57BL; Models, Theoretical; Pyrazines; Ribavirin; Treatment Outcome; Viral Load	2017
Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Fever. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017, Sep-01, Volume: 65, Issue:5 Topics: Adult; Amides; Antiviral Agents; Humans; Lassa Fever; Lassa virus; Male; Polymerase Chain Reaction; Pyrazines; Ribavirin; RNA, Viral; Togo	2017
Identification of 2'-deoxy-2'-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus. Antiviral research, 2017, Volume: 147 Topics: Amides; Antiviral Agents; Cell Line, Tumor; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Discovery; Drug Synergism; Genes, Reporter; Green Fluorescent Proteins; Hemorrhagic Fever Virus, Crimean-Congo; Hemorrhagic Fever, Crimean; High-Throughput Screening Assays; Humans; Lethal Dose 50; Pyrazines; Ribavirin; Viral Proteins; Virus Replication	2017
Establishment of an antiviral assay system and identification of severe fever with thrombocytopenia syndrome virus inhibitors. Antiviral chemistry & chemotherapy, 2017, Volume: 25, Issue:3 Topics: Amides; Amodiaquine; Animals; Antiviral Agents; Bunyaviridae; Bunyaviridae Infections; Cell Line; Chlorocebus aethiops; Fever; Humans; Microbial Sensitivity Tests; Pyrazines; Ribavirin; Thrombocytopenia; Virus Replication	2017
Zika Virus Replication Is Substantially Inhibited by Novel Favipiravir and Interferon Alpha Combination Regimens. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:1 Topics: Amides; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; DNA Replication; Humans; Interferon-alpha; Pyrazines; Ribavirin; Vero Cells; Viral Load; Virus Replication; Zika Virus; Zika Virus Infection	2018
Discharge Criteria for Patient With Lassa Fever Infection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018, 02-01, Volume: 66, Issue:4 Topics: Amides; Humans; Lassa Fever; Patient Discharge; Pyrazines; Ribavirin	2018
Reply to Nicastri et al. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018, 02-01, Volume: 66, Issue:4 Topics: Amides; Humans; Lassa Fever; Pyrazines; Ribavirin	2018
Synthesis of a Novel Class of 1,3-oxathiolane Nucleoside Derivatives of T- 705 and Evaluation of Their Anti-influenza A Virus and Anti-HIV Activity. Medicinal chemistry (Shariqah (United Arab Emirates)), 2018, Volume: 14, Issue:6 Topics: Amides; Animals; Anti-HIV Agents; Dogs; HEK293 Cells; HIV; Humans; Influenza A Virus, H1N1 Subtype; Isomerism; Madin Darby Canine Kidney Cells; Nucleosides; Pyrazines; Ribavirin; Thiophenes	2018
Favipiravir and Ribavirin Inhibit Replication of Asian and African Strains of Zika Virus in Different Cell Models. Viruses, 2018, 02-09, Volume: 10, Issue:2 Topics: Amides; Animals; Antiviral Agents; Apoptosis; Cell Line; Cell Proliferation; Chlorocebus aethiops; Humans; Pyrazines; Ribavirin; Vero Cells; Virus Replication; Zika Virus; Zika Virus Infection	2018
Evaluation of in vitro inhibitory potential of type-I interferons and different antiviral compounds on rabies virus replication. Vaccine, 2019, 08-02, Volume: 37, Issue:33 Topics: Amides; Animals; Antiviral Agents; Cell Line, Tumor; Drug Combinations; Interferon Type I; Mice; Pyrazines; Rabies virus; Real-Time Polymerase Chain Reaction; Ribavirin; Sorafenib; Virus Replication	2019
In vitro sensitivity of human parainfluenza 3 clinical isolates to ribavirin, favipiravir and zanamivir. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2018, Volume: 102 Topics: Amides; Antiviral Agents; Cell Line, Tumor; Cytopathogenic Effect, Viral; Humans; Parainfluenza Virus 3, Human; Pyrazines; Respirovirus Infections; Ribavirin; Virus Attachment; Virus Replication; Zanamivir	2018
The effect of combined drugs therapy on the course of clinical rabies infection in a murine model. Vaccine, 2019, 08-02, Volume: 37, Issue:33 Topics: Amides; Animals; Antibodies, Viral; Antiviral Agents; Disease Models, Animal; Drug Therapy, Combination; Female; Immunity, Innate; Mice; Mice, Inbred C57BL; Pyrazines; Rabies; Rabies virus; Ribavirin; Serpins; Viral Proteins; Virus Replication	2019
Effective Treatment of Experimental Lymphocytic Choriomeningitis Virus Infection: Consideration of Favipiravir for Use With Infected Organ Transplant Recipients. The Journal of infectious diseases, 2018, 07-13, Volume: 218, Issue:4 Topics: Amides; Animals; Antiviral Agents; Disease Models, Animal; Female; Immunocompromised Host; Lymphocytic Choriomeningitis; Lymphocytic choriomeningitis virus; Male; Mice, Inbred NZB; Pyrazines; Ribavirin; Survival Analysis; Transplant Recipients; Treatment Outcome; Viral Load	2018
Extinction of Zika Virus and Usutu Virus by Lethal Mutagenesis Reveals Different Patterns of Sensitivity to Three Mutagenic Drugs. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:9 Topics: Amides; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Epithelial Cells; Flavivirus; Fluorouracil; Mutagenesis; Mutagens; Mutation Rate; Nucleosides; Pyrazines; Ribavirin; Ribonucleosides; Serial Passage; Vero Cells; Virus Replication; Zika Virus; Zika Virus Infection	2018
Favipiravir (T-705) but not ribavirin is effective against two distinct strains of Crimean-Congo hemorrhagic fever virus in mice. Antiviral research, 2018, Volume: 157 Topics: Amides; Animals; Antiviral Agents; Disease Models, Animal; Hemorrhagic Fever Virus, Crimean-Congo; Hemorrhagic Fever, Crimean; Mice; Pyrazines; Ribavirin; RNA, Viral; Survival Analysis; Treatment Outcome; Viral Load	2018
Resistance of high fitness hepatitis C virus to lethal mutagenesis. Virology, 2018, Volume: 523 Topics: Amides; Antiviral Agents; Cell Line, Tumor; Drug Resistance, Viral; Genetic Fitness; Hepacivirus; Hepatocytes; Humans; Mutagenesis; Mutation; Pyrazines; Ribavirin; Serial Passage	2018
Rare haplotype load as marker for lethal mutagenesis. PloS one, 2018, Volume: 13, Issue:10 Topics: Amides; Antiviral Agents; Cell Line; Haplotypes; Hepacivirus; Humans; Mutation Rate; Nucleosides; Pyrazines; Quasispecies; Ribavirin; Serial Passage; Synthetic Lethal Mutations; Viral Nonstructural Proteins	2018
Establishment of a Cell Culture Model of Persistent Flaviviral Infection: Usutu Virus Shows Sustained Replication during Passages and Resistance to Extinction by Antiviral Nucleosides. Viruses, 2019, 06-17, Volume: 11, Issue:6 Topics: Amides; Animals; Antiviral Agents; Chlorocebus aethiops; Flavivirus; Flavivirus Infections; Models, Biological; Pyrazines; Ribavirin; RNA, Viral; Sequence Analysis, DNA; Sequence Deletion; Serial Passage; Treatment Outcome; Vero Cells; Viral Load; Viral Proteins; Virus Cultivation; Virus Replication	2019
A preclinical assessment to repurpose drugs to target type 1 diabetes-associated type B coxsackieviruses. Diabetic medicine : a journal of the British Diabetic Association, 2020, Volume: 37, Issue:11 Topics: A549 Cells; Amides; Antiviral Agents; Azithromycin; Benzimidazoles; Coxsackievirus Infections; Diabetes Mellitus, Type 1; Drug Repositioning; Enterovirus B, Human; Fluoxetine; Guanidine; Humans; Immunoglobulin G; Lovastatin; Oxadiazoles; Oxazoles; Oximes; Pyrazines; Ribavirin; Sulfonamides	2020
Antiviral activity of ribavirin and favipiravir against human astroviruses. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2020, Volume: 123 Topics: Amides; Antiviral Agents; Caco-2 Cells; Humans; Mamastrovirus; Pyrazines; Ribavirin; Virus Replication	2020
Ribavirin does not potentiate favipiravir antiviral activity against Ebola virus in non-human primates. Antiviral research, 2020, Volume: 177 Topics: Amides; Animals; Antiviral Agents; Disease Models, Animal; Ebolavirus; Female; Hemorrhagic Fever, Ebola; Macaca fascicularis; Pyrazines; Ribavirin; Viral Load; Virus Replication	2020
Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro. Antiviral research, 2020, Volume: 178 Topics: Adenosine Monophosphate; Alanine; Amides; Animals; Antimetabolites; Antiviral Agents; Betacoronavirus; Chlorocebus aethiops; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Combinations; Emetine; Epithelial Cells; Homoharringtonine; Humans; Lopinavir; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; SARS-CoV-2; Vero Cells; Virus Replication	2020
Clinical Management of Argentine Hemorrhagic Fever using Ribavirin and Favipiravir, Belgium, 2020. Emerging infectious diseases, 2020, Volume: 26, Issue:7 Topics: Amides; Animals; Belgium; Disease Models, Animal; Female; Humans; Junin virus; Pyrazines; Ribavirin	2020
Independent inhibition of the polymerase and deubiquitinase activities of the Crimean-Congo Hemorrhagic Fever Virus full-length L-protein. PLoS neglected tropical diseases, 2020, Volume: 14, Issue:6 Topics: Amides; Deubiquitinating Enzymes; DNA-Directed RNA Polymerases; Hemorrhagic Fever Virus, Crimean-Congo; Hemorrhagic Fever, Crimean; Humans; Mutation; Protein Structure, Tertiary; Pyrazines; Ribavirin; RNA, Viral; Virus Replication	2020
Interactions Between Remdesivir, Ribavirin, Favipiravir, Galidesivir, Hydroxychloroquine and Chloroquine with Fragment Molecular of the COVID-19 Main Protease with Inhibitor N3 Complex (PDB ID:6LU7) Using Molecular Docking. Journal of nanoscience and nanotechnology, 2020, 12-01, Volume: 20, Issue:12 Topics: Adenine; Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Betacoronavirus; Binding Sites; Chloroquine; Coronavirus 3C Proteases; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cysteine Endopeptidases; Drug Interactions; Humans; Hydrogen Bonding; Hydroxychloroquine; Ligands; Molecular Docking Simulation; Nanotechnology; Pandemics; Pneumonia, Viral; Protease Inhibitors; Pyrazines; Pyrrolidines; Ribavirin; SARS-CoV-2; Static Electricity; Viral Nonstructural Proteins	2020
2'-Fluoro-2'-deoxycytidine inhibits murine norovirus replication and synergizes MPA, ribavirin and T705. Archives of virology, 2020, Volume: 165, Issue:11 Topics: Amides; Animals; Antiviral Agents; Caliciviridae Infections; Cell Line; Deoxycytidine; Humans; Mice; Mycophenolic Acid; Norovirus; Pyrazines; RAW 264.7 Cells; Ribavirin; Virus Replication	2020
Antiviral Effect of Favipiravir (T-705) against Measles and Subacute Sclerosing Panencephalitis Viruses. Japanese journal of infectious diseases, 2021, Mar-24, Volume: 74, Issue:2 Topics: Amides; Animals; Antiviral Agents; Chlorocebus aethiops; Humans; Interferon-alpha; Japan; Measles; Measles virus; Microbial Sensitivity Tests; Pyrazines; Ribavirin; SSPE Virus; Subacute Sclerosing Panencephalitis; Vero Cells	2021
In Vitro Combinations of Baloxavir Acid and Other Inhibitors against Seasonal Influenza A Viruses. Viruses, 2020, 10-08, Volume: 12, Issue:10 Topics: Acids, Carbocyclic; Amides; Animals; Antiviral Agents; Cell Line; Dibenzothiepins; Dogs; Drug Combinations; Drug Resistance, Viral; Drug Synergism; Guanidines; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Madin Darby Canine Kidney Cells; Morpholines; Neuraminidase; Nucleic Acid Synthesis Inhibitors; Orthomyxoviridae Infections; Oseltamivir; Pyrazines; Pyridones; Ribavirin; Triazines; Viral Proteins; Virus Replication; Zanamivir	2020
Lassa viral dynamics in non-human primates treated with favipiravir or ribavirin. PLoS computational biology, 2021, Volume: 17, Issue:1 Topics: Amides; Animals; Antiviral Agents; Female; Host-Pathogen Interactions; Lassa Fever; Lassa virus; Macaca fascicularis; Models, Biological; Pyrazines; Ribavirin; Viral Load	2021
In silico evaluation of potential inhibitory activity of remdesivir, favipiravir, ribavirin and galidesivir active forms on SARS-CoV-2 RNA polymerase. Molecular diversity, 2022, Volume: 26, Issue:1 Topics: Adenine; Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; COVID-19 Drug Treatment; Drug Repositioning; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Pyrazines; Pyrrolidines; Ribavirin; RNA, Viral; SARS-CoV-2	2022
Combination of (interferon beta-1b, lopinavir/ritonavir and ribavirin) versus favipiravir in hospitalized patients with non-critical COVID-19: A cohort study. PloS one, 2021, Volume: 16, Issue:6 Topics: Adult; Aged; Amides; Antiviral Agents; COVID-19 Drug Treatment; Drug Therapy, Combination; Female; Hospitalization; Humans; Interferon beta-1b; Lopinavir; Male; Middle Aged; Prospective Studies; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2	2021
Generation of a Bactrian camel hepatitis E virus by a reverse genetics system. The Journal of general virology, 2021, Volume: 102, Issue:7 Topics: Amides; Animals; Antiviral Agents; Capsid Proteins; Cell Line; Female; Genome, Viral; Hepatitis E; Hepatitis E virus; Humans; Macaca fascicularis; Male; Mice; Mice, Nude; Pyrazines; Rats; Reverse Genetics; Ribavirin; RNA, Viral; Transfection; Virus Replication	2021
Effect of drug metabolism in the treatment of SARS-CoV-2 from an entirely computational perspective. Scientific reports, 2021, 10-07, Volume: 11, Issue:1 Topics: Adenine; Adenosine; Adenosine Monophosphate; Alanine; Amides; Antiviral Agents; Chloroquine; COVID-19; COVID-19 Drug Treatment; Drug Design; Drug Discovery; Humans; Metabolic Networks and Pathways; Molecular Docking Simulation; Nitro Compounds; Pyrazines; Pyrrolidines; Ribavirin; SARS-CoV-2; Thiazoles	2021
Favipiravir Inhibits Hepatitis A Virus Infection in Human Hepatocytes. International journal of molecular sciences, 2022, Feb-27, Volume: 23, Issue:5 Topics: Amides; Hepatitis A; Hepatitis A Antibodies; Hepatitis A virus; Hepatocytes; Humans; Nucleotides; Pyrazines; Ribavirin; RNA, Viral; Virus Replication	2022
Susceptibility of Type I Interferon Receptor Knock-Out Mice to Heartland Bandavirus (HRTV) Infection and Efficacy of Favipiravir and Ribavirin in the Treatment of the Mice Infected with HRTV. Viruses, 2022, 07-28, Volume: 14, Issue:8 Topics: Amides; Animals; Disease Models, Animal; Humans; Mice; Mice, Knockout; Phlebovirus; Pyrazines; Receptor, Interferon alpha-beta; Ribavirin; Solvents; Thrombocytopenia	2022
Efficient rescue of a newly classified Ebinur lake orthobunyavirus with GFP reporter and its application in rapid antiviral screening. Antiviral research, 2022, Volume: 207 Topics: Amides; Animals; Antiviral Agents; Genes, Reporter; Green Fluorescent Proteins; Humans; Mice; Orthobunyavirus; Pyrazines; Ribavirin; Tyrphostins; Virus Replication	2022