Page last updated: 2024-08-16

ribavirin and mizoribine

ribavirin has been researched along with mizoribine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (66.67)29.6817
2010's5 (27.78)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Fukushi, S; Ikejiri, M; Kurane, I; Maruyama, T; Mizutani, T; Morikawa, S; Saijo, M1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Shigeta, S1
Yamaoka, T1
Clark, JL; Lostia, S; Otto, MJ; Pankiewicz, KW; Patterson, SE; Stuyver, LJ; Watanabe, KA1
Guillén Schlippe, YV; Hedstrom, L; Riera, TV; Seyedsayamdost, MR1
Black, PL; Goldstein, BM; Jayaram, HN; Pankiewicz, KW; Patterson, SE; Risal, D; Schinazi, RF; Stuyver, LJ1
Baba, C; Baba, M; Yanagida, K1
Abe, K; Dansako, H; Ikeda, M; Kato, N; Naka, K1
Fukushi, S; Hasegawa, H; Iwata, N; Kurane, I; Mizutani, T; Morikawa, S; Nagata, N; Saijo, M1
Bailey, K; Barnard, DL; Carson, DA; Cottam, HB; Day, CW; Heiner, M; Hoopes, J; Lauridsen, L; Lee, J; Li, JK; Montgomery, R; Sidwell, RW; Winslow, S1
Kamio, Y; Mori, N; Murakami, T; Yokooji, T2
Ishiguro, M; Kamio, Y; Mori, N; Murakami, T; Shimomukai, Y; Yokooji, T1
Aboge, GO; Cao, S; Igarashi, I; Kamyingkird, K; Masatani, T; Moumouni, PF; Nishikawa, Y; Suzuki, H; Terkawi, MA; Xuan, X; Zhou, M1
Fukuma, A; Fukushi, S; Maeda, K; Morikawa, S; Saijo, M; Shimojima, M; Suda, Y; Takahashi, T; Tani, H; Taniguchi, S; Yoshikawa, T1
Cherrington, NJ; Ekins, S; Lane, TR; Miller, SR; Wright, SH; Zorn, KM1

Reviews

3 review(s) available for ribavirin and mizoribine

ArticleYear
Recent progress in antiviral chemotherapy for respiratory syncytial virus infections.
    Expert opinion on investigational drugs, 2000, Volume: 9, Issue:2

    Topics: Amides; Animals; Antibodies, Monoclonal; Antiviral Agents; Biopolymers; Bridged-Ring Compounds; Catechin; Drugs, Investigational; Heterocyclic Compounds; Humans; Immunoglobulins, Intravenous; Lipids; N-Acetylneuraminic Acid; Norbornanes; Oligodeoxyribonucleotides, Antisense; Pyrazoles; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Ribavirin; Ribonucleosides; Ribose; Risk Factors; Thiocarbamates; Thiones

2000
[IMP dehydrogenase].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 1

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Feedback, Physiological; Genes, Dominant; Guanosine Monophosphate; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Mycophenolic Acid; Pigment Epithelium of Eye; Protein Conformation; Protein Structure, Tertiary; Purine Nucleotides; Retinal Degeneration; Ribavirin; Ribonucleosides

2003
Cofactor mimics as selective inhibitors of NAD-dependent inosine monophosphate dehydrogenase (IMPDH)--the major therapeutic target.
    Current medicinal chemistry, 2004, Volume: 11, Issue:7

    Topics: Catalysis; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Molecular Mimicry; Molecular Structure; Mycophenolic Acid; NAD; Ribavirin; Ribonucleosides

2004

Other Studies

15 other study(ies) available for ribavirin and mizoribine

ArticleYear
Synthesis and biological evaluation of nucleoside analogues having 6-chloropurine as anti-SARS-CoV agents.
    Bioorganic & medicinal chemistry letters, 2007, May-01, Volume: 17, Issue:9

    Topics: Animals; Antiviral Agents; Chemistry, Pharmaceutical; Chlorocebus aethiops; Dose-Response Relationship, Drug; Drug Design; Evaluation Studies as Topic; Inhibitory Concentration 50; Models, Chemical; Molecular Conformation; Nucleosides; Purines; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; Vero Cells

2007
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Inhibitors of the IMPDH enzyme as potential anti-bovine viral diarrhoea virus agents.
    Antiviral chemistry & chemotherapy, 2002, Volume: 13, Issue:6

    Topics: Animals; Cattle; Cell Line; Computer Systems; Culture Media, Conditioned; Diarrhea Viruses, Bovine Viral; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Guanosine Triphosphate; IMP Dehydrogenase; Kidney; Molecular Structure; Mycophenolic Acid; NAD; Nucleosides; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; Ribonucleosides; Viral Plaque Assay; Virus Replication

2002
Substitution of the conserved Arg-Tyr dyad selectively disrupts the hydrolysis phase of the IMP dehydrogenase reaction.
    Biochemistry, 2004, Apr-20, Volume: 43, Issue:15

    Topics: Adenosine Diphosphate; Alanine; Amino Acid Substitution; Animals; Arginine; Binding Sites; Cattle; Conserved Sequence; Deuterium Exchange Measurement; Enzyme Inhibitors; Hydrolysis; IMP Dehydrogenase; Kinetics; Mutagenesis, Site-Directed; Mycophenolic Acid; Phenylalanine; Point Mutation; Protein Binding; Ribavirin; Ribonucleosides; Ribonucleotides; Solvents; Substrate Specificity; Tritrichomonas foetus; Tyrosine; Xanthine

2004
Inhibition of bovine viral diarrhea virus (BVDV) by mizoribine: synergistic effect of combination with interferon-alpha.
    Antiviral research, 2004, Volume: 64, Issue:3

    Topics: Animals; Cattle; Diarrhea Viruses, Bovine Viral; Drug Synergism; Drug Therapy, Combination; Hepacivirus; Interferon-alpha; Ribavirin; Ribonucleosides; Tumor Cells, Cultured

2004
Mizoribine inhibits hepatitis C virus RNA replication: effect of combination with interferon-alpha.
    Biochemical and biophysical research communications, 2005, May-13, Volume: 330, Issue:3

    Topics: Antiviral Agents; Cell Line; Clone Cells; Genes, Reporter; Genome, Viral; Hepacivirus; Inhibitory Concentration 50; Interferon-alpha; Luciferases, Renilla; Ribavirin; Ribonucleosides; RNA, Viral; Virus Replication

2005
Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus.
    Antiviral research, 2005, Volume: 66, Issue:2-3

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Microbial Sensitivity Tests; Ribavirin; Ribonucleosides; Severe acute respiratory syndrome-related coronavirus; Vero Cells; Virus Replication

2005
Enhancement of the infectivity of SARS-CoV in BALB/c mice by IMP dehydrogenase inhibitors, including ribavirin.
    Antiviral research, 2006, Volume: 71, Issue:1

    Topics: Animals; Antiviral Agents; Caco-2 Cells; Cell Survival; Chlorocebus aethiops; Cytokines; Cytopathogenic Effect, Viral; Female; Humans; IMP Dehydrogenase; Lung; Mice; Mice, Inbred BALB C; Mycophenolic Acid; Oligonucleotide Array Sequence Analysis; Ribavirin; Ribonucleosides; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; Specific Pathogen-Free Organisms; Vero Cells; Virus Replication

2006
Characterization of intestinal absorption of mizoribine mediated by concentrative nucleoside transporters in rats.
    European journal of pharmacology, 2008, May-31, Volume: 586, Issue:1-3

    Topics: Animals; Antimetabolites; Bile Acids and Salts; Biological Availability; Carrier Proteins; Deoxycytidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gemcitabine; In Vitro Techniques; Intestinal Absorption; Male; Membrane Transport Proteins; Nucleosides; Rats; Rats, Sprague-Dawley; Ribavirin; Ribonucleosides

2008
Study on intestinal absorption sites of mizoribine and ribavirin, substrates for concentrative nucleoside transporter(s), in rats.
    European journal of pharmacology, 2010, Feb-25, Volume: 628, Issue:1-3

    Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Gastric Emptying; Intestinal Absorption; Kinetics; Male; Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Ribavirin; Ribonucleosides

2010
Modulation in concentrative nucleoside transporters-mediated intestinal absorption of mizoribine, an immunosuppressive agent, in lipopolysaccharide-treated rats.
    Die Pharmazie, 2011, Volume: 66, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Antiviral Agents; Bile; Biological Availability; Cephalexin; Cholestasis; Chromatography, High Pressure Liquid; Deoxycytidine; Gemcitabine; Immunosuppressive Agents; In Vitro Techniques; Inflammation; Intestinal Absorption; Lipopolysaccharides; Male; Nucleoside Transport Proteins; Rats; Rats, Sprague-Dawley; Ribavirin; Ribonucleosides

2011
Mycophenolic acid, mycophenolate mofetil, mizoribine, ribavirin, and 7-nitroindole inhibit propagation of Babesia parasites by targeting inosine 5'-monophosphate dehydrogenase.
    The Journal of parasitology, 2014, Volume: 100, Issue:4

    Topics: Animals; Babesia; Cattle; Enzyme Inhibitors; Female; IMP Dehydrogenase; Inhibitory Concentration 50; Mice; Mice, Inbred ICR; Mycophenolic Acid; Ribavirin; Ribonucleosides

2014
Effects of ribavirin on severe fever with thrombocytopenia syndrome virus in vitro.
    Japanese journal of infectious diseases, 2014, Volume: 67, Issue:6

    Topics: Antiviral Agents; Cell Line; Humans; Microbial Sensitivity Tests; Phlebovirus; Ribavirin; Ribonucleosides

2014
Multiple Computational Approaches for Predicting Drug Interactions with Human Equilibrative Nucleoside Transporter 1.
    Drug metabolism and disposition: the biological fate of chemicals, 2021, Volume: 49, Issue:7

    Topics: Darunavir; Drug Interactions; Equilibrative Nucleoside Transporter 1; HeLa Cells; Humans; Nucleosides; Ribavirin; Ribonucleosides; Thioinosine

2021