Page last updated: 2024-08-16

ribavirin and methotrexate

ribavirin has been researched along with methotrexate in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's3 (11.54)18.2507
2000's8 (30.77)29.6817
2010's12 (46.15)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Cichero, E; Costi, MP; Gazzarrini, S; Loddo, R; Moroni, A; Naesens, L; Santucci, M; Tasso, B; Tonelli, M1
Bernatchez, JA; Li, J; Li, R; Luan, Y; Siqueira-Neto, JL; Tran, LT1
Garin, AM; Lobova, TG; Preobrazhenskaia, MN; Zharkov, SA1
Prajda, N; Singhal, RL; Weber, G1
Olah, E; Sledge, GW; Weber, G; Wendel, JJ; Yeh, YA1
Prajda, N; Weber, G1
De Abreu, RA; Lambooy, LH; Trueworthy, RC; van Gennip, AH; van Kuilenburg, AB; Vogels-Mentink, TM1
Bonney, D; Razali, H; Turner, A; Will, A1
Di Lernia, V1
Binh, NT; Kawaguchi, A; Nagata, K; Wakai, C1
Ledeboer, M; Martens, HA; van Bijnen, ST1
Fernando, D; Herath, T; Rajapakse, S; Rodrigo, C; Wickramarachchi, U1

Reviews

4 review(s) available for ribavirin and methotrexate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drugs for the Treatment of Zika Virus Infection.
    Journal of medicinal chemistry, 2020, 01-23, Volume: 63, Issue:2

    Topics: Animals; Antiviral Agents; Drug Development; Drug Discovery; Humans; Viral Vaccines; Zika Virus; Zika Virus Infection

2020
Antimetabolites reduce the activities of enzymes with short half-lives in addition to inhibiting their specific targets.
    Advances in experimental medicine and biology, 1994, Volume: 370

    Topics: Animals; Antimetabolites, Antineoplastic; Bone Marrow; Cycloheximide; Enzyme Inhibitors; Fluorouracil; Half-Life; Humans; Isoxazoles; Methotrexate; Prodrugs; Purines; Pyrimidines; Ribavirin; Signal Transduction

1994
Treatment of chikungunya-associated joint pain: a systematic review of controlled clinical trials.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2022, 10-02, Volume: 116, Issue:10

    Topics: Anti-Inflammatory Agents; Arthralgia; Chikungunya Fever; Chloroquine; Humans; Hydroxychloroquine; Methotrexate; Observational Studies as Topic; Retrospective Studies; Ribavirin

2022

Other Studies

22 other study(ies) available for ribavirin and methotrexate

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus.
    European journal of medicinal chemistry, 2017, Jul-28, Volume: 135

    Topics: Antiviral Agents; Crystallography, X-Ray; Dose-Response Relationship, Drug; Folic Acid Antagonists; Humans; Influenza A Virus, H1N1 Subtype; Influenza B virus; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Proguanil; Respiratory Syncytial Viruses; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Triazines

2017
[Ribamidyl (ribavirin) as a modulator of the biological action of arabinosylcytosine and methotrexate].
    Eksperimental'naia onkologiia, 1985, Volume: 7, Issue:3

    Topics: Animals; Cytarabine; Drug Evaluation, Preclinical; Drug Synergism; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Ribavirin; Ribonucleosides

1985
Synergistic action of taxol with tiazofurin and methotrexate in human breast cancer cells: schedule-dependence.
    Life sciences, 1994, Volume: 54, Issue:24

    Topics: Cell Division; Drug Synergism; Female; Humans; Methotrexate; Paclitaxel; Ribavirin; Tumor Cells, Cultured

1994
Targeted and non-targeted actions of anti-cancer drugs.
    Advances in enzyme regulation, 1994, Volume: 34

    Topics: Animals; Antimetabolites, Antineoplastic; Bone Marrow; Cycloheximide; Deoxycytidine Kinase; Fluorouracil; Hypoxanthine Phosphoribosyltransferase; Isoxazoles; Methotrexate; Neoplasms, Experimental; Pyrimidines; Rats; Rats, Inbred Strains; Ribavirin; Thymidine Kinase; Thymidylate Synthase

1994
Combination therapy in childhood leukaemia: in vitro studies of thiopurines and inhibitors of purine metabolism on apoptosis.
    Annals of clinical biochemistry, 2003, Volume: 40, Issue:Pt 1

    Topics: Annexin A5; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Survival; Child; Coloring Agents; Humans; Leukemia; Mercaptopurine; Methotrexate; Models, Biological; Purines; Ribavirin; Thioguanine; Time Factors; Tumor Cells, Cultured

2003
Successful treatment of human metapneumovirus pneumonia using combination therapy with intravenous ribavirin and immune globulin.
    British journal of haematology, 2009, Volume: 145, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Asparaginase; Child, Preschool; Combined Modality Therapy; Daunorubicin; Female; Humans; Immunocompromised Host; Immunoglobulins, Intravenous; Metapneumovirus; Methotrexate; Paramyxoviridae Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Ribavirin; Vincristine

2009
Treatment of psoriasis in patients with hepatitis C virus infection.
    Clinical and experimental dermatology, 2011, Volume: 36, Issue:4

    Topics: Acitretin; Antiviral Agents; Cyclosporine; Drug Eruptions; Hepatitis C, Chronic; Humans; Immunosuppressive Agents; Interferon-alpha; Methotrexate; Psoriasis; Ribavirin

2011
Involvement of the N-terminal portion of influenza virus RNA polymerase subunit PB1 in nucleotide recognition.
    Biochemical and biophysical research communications, 2014, Jan-17, Volume: 443, Issue:3

    Topics: Animals; Base Sequence; DNA Mutational Analysis; Dogs; Drug Resistance, Viral; HEK293 Cells; Humans; Madin Darby Canine Kidney Cells; Methotrexate; Molecular Sequence Data; Mutant Proteins; Mutation; Nucleotides; Protein Subunits; Replicon; Ribavirin; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Viral Proteins

2014
Chronic hepatitis E in a patient with rheumatoid arthritis treated with adalimumab and methotrexate.
    Rheumatology (Oxford, England), 2017, Mar-01, Volume: 56, Issue:3

    Topics: Adalimumab; Antirheumatic Agents; Antiviral Agents; Arthritis, Rheumatoid; Hepatitis E; Hepatitis, Chronic; Humans; Immunocompromised Host; Male; Methotrexate; Middle Aged; Ribavirin

2017