Page last updated: 2024-08-16

ribavirin and inosinic acid

ribavirin has been researched along with inosinic acid in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19906 (33.33)18.7374
1990's11 (61.11)18.2507
2000's1 (5.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carson, DA; Seegmiller, JE; Willis, RC1
Nagai, M; Nakamura, H; Natsumeda, Y; Szekeres, T; Weber, G1
Balzarini, J; De Clercq, E; Lee, CK; Schols, D1
Ahluwalia, GS; Broder, S; Cooney, DA; Fridland, A; Hartman, NR; Johns, DG; Kageyama, S; Mitsuya, H1
Balzarini, J; De Clercq, E; Herdewijn, P; Lee, CK1
Fujitaki, JM; Kini, GD; Lee, VM; Matsumoto, SS; Nord, LD; Revankar, GR; Robins, RK; Sanghvi, YS; Sharma, BS; Willis, RC1
Goto, H; Ogasawara, N; Yamada, Y; Yoshino, M1
Alvarez, E; Robins, RK; Saunders, PP; Spindler, CD; Tan, MT1
Belei, M; Parandoosh, Z; Robins, RK; Rubalcava, B1
Faderan, MA; Jayaram, HN; Lui, MS; Pillwein, K; Weber, G1
Connelly, MC; Fridland, A; Robbins, TJ1
Faderan, MA; Jayaram, HN; Liepnieks, JJ; Lui, MS; Natsumeda, Y; Olah, E; Weber, G1
Watts, RW1
Barzi, A; Cappellacci, L; Carrell, C; Franchetti, P; Goldstein, BM; Grifantini, M; Jayaram, HN; Nocentini, G; O'Connor, A; Yang, H1
Shipitsyn, AV; Shirokova, EA1
Cappellacci, L; De Montis, A; Franchetti, P; Goldstein, BM; Grifantini, M; Gurudutt, VV; Jayaram, HN; Jones, WD; La Colla, P; Loi, AG; Perra, G; Schneider, BP; Sheikha, GA; Sint, T1
Li, W; Shen, F; Weber, G1
Luecke, H; Prosise, GL1

Reviews

2 review(s) available for ribavirin and inosinic acid

ArticleYear
Some regulatory and integrative aspects of purine nucleotide biosynthesis and its control: an overview.
    Advances in enzyme regulation, 1983, Volume: 21

    Topics: Adenylosuccinate Synthase; Alanine; Animals; Brain; Formates; Humans; IMP Dehydrogenase; Inosine Monophosphate; Liver; Lymphocyte Activation; Purine Nucleotides; Rats; Ribavirin; Ribonucleotides; S-Adenosylhomocysteine

1983
Role of purine metabolism in regulation of signal transduction in human carcinoma cells.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Antimetabolites, Antineoplastic; Deoxyguanine Nucleotides; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Inosine Monophosphate; Leukemia; Neoplasms; Purines; Ribavirin; Signal Transduction

1998

Other Studies

16 other study(ies) available for ribavirin and inosinic acid

ArticleYear
Adenosine kinase initiates the major route of ribavirin activation in a cultured human cell line.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:7

    Topics: Adenosine Kinase; Cell Line; Formates; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; IMP Dehydrogenase; Inosine; Inosine Monophosphate; Lymphocytes; Phosphates; Phosphotransferases; Ribavirin; Ribonucleosides

1978
Regulation of GTP biosynthesis.
    Advances in enzyme regulation, 1992, Volume: 32

    Topics: Animals; Cell Differentiation; Cell Division; Colonic Neoplasms; Evaluation Studies as Topic; GMP Reductase; Guanosine Monophosphate; Guanosine Triphosphate; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Inosine Monophosphate; Leukemia, Promyelocytic, Acute; Liver Neoplasms, Experimental; NADH, NADPH Oxidoreductases; Ribavirin; Tumor Cells, Cultured

1992
1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (ribavirin) and 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide (EICAR) markedly potentiate the inhibitory effect of 2',3'-dideoxyinosine on human immunodeficiency virus in peripheral blood lymph
    Biochemical and biophysical research communications, 1991, Jul-31, Volume: 178, Issue:2

    Topics: Antiviral Agents; Cells, Cultured; Didanosine; Drug Synergism; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; HIV-1; Humans; Inosine Monophosphate; Kinetics; Lymphocytes; Ribavirin; Ribonucleosides

1991
Inhibitors of IMP dehydrogenase stimulate the phosphorylation of the anti-human immunodeficiency virus nucleosides 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine.
    Molecular pharmacology, 1991, Volume: 40, Issue:1

    Topics: Antiviral Agents; Cells, Cultured; Chromatography; Didanosine; Dideoxyadenosine; Drug Synergism; HIV; Humans; IMP Dehydrogenase; Inosine; Inosine Monophosphate; Nucleotides; Phosphorylation; Ribavirin; Stimulation, Chemical

1991
Mechanism of the potentiating effect of ribavirin on the activity of 2',3'-dideoxyinosine against human immunodeficiency virus.
    The Journal of biological chemistry, 1991, Nov-15, Volume: 266, Issue:32

    Topics: Biotransformation; Cell Line; Didanosine; Drug Synergism; Giant Cells; Guanine Nucleotides; HIV-1; Humans; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Kinetics; Models, Biological; Ribavirin

1991
Inhibition of pyrimidine metabolism in myeloid leukemia cells by triazole and pyrazole nucleosides.
    Biochemical pharmacology, 1990, Feb-01, Volume: 39, Issue:3

    Topics: Adenosine Triphosphate; Cell Division; Guanosine Triphosphate; Hemoglobins; Humans; IMP Dehydrogenase; Inosine Monophosphate; Interphase; Leukemia, Myeloid; Molecular Structure; Orotic Acid; Pyrazoles; Pyrimidine Nucleotides; Ribavirin; Ribonucleosides; Tumor Cells, Cultured; Uridine Triphosphate

1990
IMP dehydrogenase and action of antimetabolites in human cultured blast cells.
    Biochimica et biophysica acta, 1990, Mar-09, Volume: 1051, Issue:3

    Topics: Adenine Nucleotides; Antimetabolites, Antineoplastic; Cell Division; Cell Line; Humans; IMP Dehydrogenase; Inosine Monophosphate; Ketone Oxidoreductases; Kinetics; Leukemia; NAD; Ribavirin; Ribonucleosides

1990
Tiazofurin is phosphorylated by three enzymes from Chinese hamster ovary cells.
    Cancer research, 1990, Sep-01, Volume: 50, Issue:17

    Topics: Adenosine Kinase; Adenosine Triphosphate; Animals; Antimetabolites, Antineoplastic; Biotransformation; Cell Line; Cricetinae; Cricetulus; Female; Inosine Monophosphate; Kinetics; Niacinamide; Ovary; Phosphorylation; Pyridinium Compounds; Ribavirin; Ribonucleosides

1990
Tiazofurin and selenazofurin induce depression of cGMP and phosphatidylinositol pathway in L1210 leukemia cells.
    Biochemical and biophysical research communications, 1989, Oct-31, Volume: 164, Issue:2

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Caenorhabditis elegans Proteins; Carrier Proteins; Cyclic GMP; Diglycerides; Guanosine Triphosphate; Inosine Monophosphate; Leukemia L1210; Mice; Organoselenium Compounds; Phorbol 12,13-Dibutyrate; Phosphates; Phosphatidylinositols; Protein Kinase C; Receptors, Drug; Ribavirin; Ribonucleosides; Selenium

1989
Mechanism of resistance to tiazofurin in hepatoma 3924A.
    Biochemical pharmacology, 1986, Feb-15, Volume: 35, Issue:4

    Topics: Adenosine Monophosphate; Animals; Antineoplastic Agents; Biological Transport; Cell Cycle; Cell Line; Drug Resistance; Guanine; Guanosine Monophosphate; IMP Dehydrogenase; Inosine Monophosphate; Liver Neoplasms, Experimental; Nicotinamide-Nucleotide Adenylyltransferase; Rats; Ribavirin; Ribonucleosides

1986
Tiazofurin metabolism in human lymphoblastoid cells: evidence for phosphorylation by adenosine kinase and 5'-nucleotidase.
    Cancer research, 1986, Volume: 46, Issue:2

    Topics: 5'-Nucleotidase; Adenosine Kinase; Adenosine Triphosphate; Amides; Biotransformation; Cell Line; Drug Resistance; Humans; Inosine Monophosphate; Lymphocytes; Nucleotidases; Phosphorylation; Phosphotransferases; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Substrate Specificity

1986
Modulation of IMP dehydrogenase activity and guanylate metabolism by tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide).
    The Journal of biological chemistry, 1984, Apr-25, Volume: 259, Issue:8

    Topics: Animals; Antineoplastic Agents; Cell Line; Deoxyribonucleotides; Guanine Nucleotides; Guanosine Triphosphate; IMP Dehydrogenase; Inosine Monophosphate; Ketone Oxidoreductases; Kinetics; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred ACI; Ribavirin; Ribonucleosides

1984
Furanfurin and thiophenfurin: two novel tiazofurin analogues. Synthesis, structure, antitumor activity, and interactions with inosine monophosphate dehydrogenase.
    Journal of medicinal chemistry, 1995, Sep-15, Volume: 38, Issue:19

    Topics: Animals; Antineoplastic Agents; Crystallography, X-Ray; Humans; IMP Dehydrogenase; Inosine Monophosphate; Magnetic Resonance Spectroscopy; Mice; NAD; Neoplasms; Ribavirin; Ribonucleosides; Ribonucleotides; Tumor Cells, Cultured

1995
[Ribonucleoside-5'-monophosphates with disubstituted phosphate residue do not interact with human inosine monophosphate dehydrogenase].
    Bioorganicheskaia khimiia, 1997, Volume: 23, Issue:1

    Topics: Allosteric Regulation; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Inosine Monophosphate; Ribavirin; Substrate Specificity

1997
Synthesis, structure, and antiproliferative activity of selenophenfurin, an inosine 5'-monophosphate dehydrogenase inhibitor analogue of selenazofurin.
    Journal of medicinal chemistry, 1997, May-23, Volume: 40, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Division; Computer Simulation; Crystallography, X-Ray; Enzyme Inhibitors; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Inosine Monophosphate; Leukemia; Lymphoma; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Structure; Neoplasms; Organoselenium Compounds; Ribavirin; Ribonucleosides; Tumor Cells, Cultured

1997
Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
    Journal of molecular biology, 2003, Feb-14, Volume: 326, Issue:2

    Topics: Animals; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Inosine Monophosphate; Kinetics; Models, Molecular; Mycophenolic Acid; NAD; Protein Conformation; Ribavirin; Ribonucleotides; Tritrichomonas foetus; Xanthine

2003