Compounds > ribavirin
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ribavirin and hypoxanthine

ribavirin has been researched along with hypoxanthine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's8 (80.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagai, M; Nakamura, H; Natsumeda, Y; Szekeres, T; Weber, G1
Eble, JN; Hoffman, R; Jayaram, HN; Nagai, M; Natsumeda, Y; Paulik, E; Tricot, G; Weber, G; Zhen, WN1
Balzarini, J; De Clercq, E; Herdewijn, P; Lee, CK1
Collart, FR; Henning-Chubb, C; Huberman, E; Kiguchi, K1
Weber, G1
Knight, RD; Lucas, DL; Robins, RK; Wright, DG1
Chiba, P; Gharehbaghi, K; Lhotka, C; Pillwein, K; Ressmann, G; Schuchter, K; Szalay, SM; Szekeres, T1
Findenig, G; Fritzer, M; Lhotka, C; Schön, HJ; Szekeres, T1
Hata, Y; Natsumeda, Y; Weber, G1
Cinti, C; Falcieri, E; Gobbi, P; Santi, S; Vitale, M; Weber, G; Zamai, L; Zauli, G1

Trials

1 trial(s) available for ribavirin and hypoxanthine

ArticleYear
Tiazofurin down-regulates expression of c-Ki-ras oncogene in a leukemic patient.
    Cancer communications, 1991, Volume: 3, Issue:3

    Topics: Adenine Nucleotides; Antimetabolites, Antineoplastic; Blast Crisis; Blotting, Northern; Down-Regulation; Gene Expression Regulation; Genes, ras; Guanosine Triphosphate; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Pilot Projects; Ribavirin; RNA; Uric Acid

1991

Other Studies

9 other study(ies) available for ribavirin and hypoxanthine

ArticleYear
Regulation of GTP biosynthesis.
    Advances in enzyme regulation, 1992, Volume: 32

    Topics: Animals; Cell Differentiation; Cell Division; Colonic Neoplasms; Evaluation Studies as Topic; GMP Reductase; Guanosine Monophosphate; Guanosine Triphosphate; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Inosine Monophosphate; Leukemia, Promyelocytic, Acute; Liver Neoplasms, Experimental; NADH, NADPH Oxidoreductases; Ribavirin; Tumor Cells, Cultured

1992
Mechanism of the potentiating effect of ribavirin on the activity of 2',3'-dideoxyinosine against human immunodeficiency virus.
    The Journal of biological chemistry, 1991, Nov-15, Volume: 266, Issue:32

    Topics: Biotransformation; Cell Line; Didanosine; Drug Synergism; Giant Cells; Guanine Nucleotides; HIV-1; Humans; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Kinetics; Models, Biological; Ribavirin

1991
Cell differentiation and altered IMP dehydrogenase expression induced in human T-lymphoblastoid leukemia cells by mycophenolic acid and tiazofurin.
    Experimental cell research, 1990, Volume: 187, Issue:1

    Topics: Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Survival; Gene Expression; Guanosine; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Leukemia-Lymphoma, Adult T-Cell; Mycophenolic Acid; Ribavirin; Ribonucleosides; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Critical issues in chemotherapy with tiazofurin.
    Advances in enzyme regulation, 1989, Volume: 29

    Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Down-Regulation; Drug Interactions; Female; Genes, ras; Guanine; Humans; Hypoxanthine; Hypoxanthines; Leukemia; Liver Neoplasms, Experimental; Male; Middle Aged; Ribavirin; Ribonucleosides; Tretinoin; Tumor Cells, Cultured; Uric Acid

1989
Induced maturation of the human promyelocytic leukemia cell line, HL-60, by 2-beta-D-ribofuranosylselenazole-4-carboxamide.
    Biochemical and biophysical research communications, 1983, Sep-30, Volume: 115, Issue:3

    Topics: Carbon Radioisotopes; Cell Division; Cell Line; Cell Survival; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Kinetics; Leukemia, Myeloid, Acute; Organoselenium Compounds; Oxidation-Reduction; Phagocytosis; Ribavirin; Ribonucleosides; Selenium

1983
Synergistic action of tiazofurin with hypoxanthine and allopurinol in human neuroectodermal tumor cell lines.
    Biochemical pharmacology, 1993, Dec-03, Volume: 46, Issue:11

    Topics: Allopurinol; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Guanosine Monophosphate; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Neuroblastoma; Ribavirin; Tumor Cells, Cultured

1993
[Synergistic cytotoxic effects of chemotherapy in colon tumor cells by simultaneous inhibition of de novo and salvage energy metabolism pathways].
    Wiener klinische Wochenschrift, 1994, Volume: 106, Issue:14

    Topics: Allopurinol; Antimetabolites, Antineoplastic; Benzamidines; Cell Line; Cell Survival; Colonic Neoplasms; Cytarabine; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Gemcitabine; Humans; Hypoxanthine; Hypoxanthines; Ribavirin; Ribonucleotide Reductases; Tumor Cells, Cultured; Tumor Stem Cell Assay

1994
Tiazofurin decreases Ras-GTP complex in K562 cells.
    Oncology research, 1993, Volume: 5, Issue:4-5

    Topics: Antimetabolites, Antineoplastic; Cell Differentiation; Guanosine; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Oncogene Protein p21(ras); Protein Binding; Ribavirin; Tumor Cells, Cultured

1993
IMP dehydrogenase inhibitor, tiazofurin, induces apoptosis in K562 human erythroleukemia cells.
    Cytometry, 1997, Feb-15, Volume: 30, Issue:1

    Topics: Apoptosis; DNA Fragmentation; Enzyme Inhibitors; Flow Cytometry; Guanosine Triphosphate; Humans; Hypoxanthine; IMP Dehydrogenase; Leukemia, Erythroblastic, Acute; Ribavirin; Tumor Cells, Cultured

1997