ribavirin has been researched along with guanosine in 58 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 18 (31.03) | 18.7374 |
1990's | 14 (24.14) | 18.2507 |
2000's | 14 (24.14) | 29.6817 |
2010's | 12 (20.69) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Chu, YK; Chung, DH; Jonsson, CB; Parker, WB; Sun, Y | 1 |
Murphy, MF | 1 |
Browne, MJ | 1 |
Katz, E; Margalith, E; Winer, B | 1 |
Revankar, GR; Robins, RK | 1 |
Oxford, JS | 1 |
Nagai, M; Natsumeda, Y; Weber, G | 1 |
Harada, T; Hatakeyama, K; Kagamiyama, H | 1 |
Pancheva, SN | 1 |
Plunkett, W; Saunders, PP | 1 |
Collart, FR; Henning-Chubb, C; Huberman, E; Kiguchi, K | 2 |
Irino, S; Natsumeda, Y; Weber, G; Yamada, Y; Yamaji, Y | 1 |
Sartorelli, AC; Sokoloski, JA | 2 |
Hoffman, R; Jayaram, HN; Lapis, E; Natsumeda, Y; Olah, E; Prajda, N; Tricot, GJ; Weber, G; Yamaji, Y; Zhen, WN | 1 |
Blair, OC; Sartorelli, AC; Sokoloski, JA | 1 |
Kirsi, JJ; McKernan, PA; Murray, BK; North, JA; Revankar, GR; Robins, RK | 1 |
Wright, DG | 1 |
Kerr, SJ | 1 |
Robins, RK; Saunders, PP; Spindler, CD; Tan, MT | 1 |
Gilbert, BE; Knight, V; Noall, MW; Wray, SK | 1 |
Cooney, DA; Glazer, RI; Jayaram, HN; Johns, DG; Smith, AL | 1 |
Alling, DW; Knight, V; Longoria, RM; Moore, RV; Wilson, SZ | 1 |
Barnett, BB; Clark, SM; Sidwell, RW; Smee, DF; Spendlove, RS | 1 |
Boyd, VL; Jacobsen, SJ; Mangum, JH; Nyhan, WL; Page, TT; Robins, RK; Smejkal, RM | 1 |
Burns, NJ; Kirsi, JJ; McKernan, PA; Murray, BK; North, JA; Robins, RK | 1 |
Beckstead, JH; Kerby, S; Majumdar, A; Mullikin, B; Seidman, MM; Stenberg, PE | 1 |
Balzarini, J; Bohman, C; De Clercq, E; Fridland, A; Herdewijn, P; Horská, K; Karlsson, A; Van Aerschot, A; Votruba, I; Wang, L | 1 |
Hata, Y; Natsumeda, Y; Weber, G | 1 |
De Clercq, E; Hosoya, M; Ishii, T; Shigeta, S; Suzuki, H | 1 |
Iakovleva, EP; Mosunova, TV | 1 |
Averett, DR; Briese, T; Jordan, I; Lipkin, WI | 1 |
Jain, J; Kwong, AD; Markland, W; McQuaid, TJ | 1 |
De Clercq, E; Neyts, J; Ying, C | 1 |
Beames, B; Brasky, KM; Chavez, D; Guerra, B; Hong, Z; Lanford, RE; Lau, JY | 1 |
Baroudy, BM; Liu, R; Malcolm, BA; Reyes, GR; Zhou, S | 1 |
Airaksinen, A; Domingo, E; Menéndez-Arias, L; Pariente, N | 1 |
Coombs, KM; Hermann, LL; Robertson, CM | 1 |
Borden, KL; Culjkovic, B; Kentsis, A; Shao, L; Topisirovic, I | 1 |
Carlson, EJ; Ferrin, TE; Giacomini, KM; Gray, JH; Huang, CC; Johns, SJ; Kawamoto, M; Owen, RP; Stryke, D; Taylor, TR | 1 |
Bisaillon, M; Lee, JM; Pelletier, J; Svitkin, Y; Yan, Y | 1 |
Bajin-Katić, K; Kovacević, Z; Oros, J | 1 |
Beeren, L; Darzynkiewicz, E; Grudzien, E; Jemielity, J; Preiss, T; Rhoads, RE; Stepinski, J; Stolarski, R; Westman, B; Worch, R; Zuberek, J | 1 |
Arterburn, JB; Chu, YK; Chung, DH; Jonsson, CB; Kumarapperuma, SC; Li, Q; Parker, WB; Ramanathan, HN; Schmaljohn, CS; Smith, J; Spik, K; Sun, Y | 1 |
Endres, CJ; Govindarajan, R; LeCluyse, E; Pastor-Anglada, M; Tse, CM; Unadkat, JD; Whittington, D | 1 |
Feld, JJ; Fried, MW; Hu, Z; Li, Q; Liang, TJ; Thomas, E | 1 |
Ariumi, Y; Dansako, H; Ikeda, M; Kato, N; Mori, K; Wakita, T | 1 |
Chen, N; Deng, A; Liang, Y; Wen, T; Xu, Q; Zhang, G | 1 |
Günther, S; Neyts, J; Ölschläger, S | 1 |
Cortez-San Martin, M; Mora, P; Reyes-Lopez, F; Rivas-Aravena, A; Sandino, AM; Spencer, E; Tello, M; Vallejos-Vidal, E | 1 |
Cai, J; Cen, P; Huang, L; Liu, Y; Luo, W; Xu, Z; Zhao, W; Zhu, X | 1 |
Mirzaei kalar, Z; Moghadam, NH; Shahabadi, N | 1 |
Cheung, PP; Choy, KT; Fun Sia, S; Guan, Y; Kellam, P; Malik Peiris, JS; Poon, LL; Watson, SJ; Wong, DD; Yen, HL | 1 |
Felczak, K; Metselaar, HJ; Pan, Q; Pankiewicz, KW; Peppelenbosch, MP; Raat, NJ; Shokrollahi, E; Sprengers, D; van der Laan, LJ; Wang, W; Wang, Y; Xu, L; Zhou, X | 1 |
Cai, X; Chang, QY; Guo, FC; Li, XR; Ma, XX; Pan, Q; Zhou, JH | 1 |
Mastrodomenico, V; Mounce, BC; Tate, PM | 1 |
Hirai, K; Kawano, M; Kihira-Nakanishi, S; Komada, H; Nishio, M; O'Brien, M; Sakai-Sugino, K; Tsurudome, M; Uematsu, J; Yamamoto, H | 1 |
1 review(s) available for ribavirin and guanosine
Article | Year |
---|---|
Metabolism and action of purine nucleoside analogs.
Topics: 2-Chloroadenosine; Adenosine; Cladribine; Deoxyadenosines; Guanine; Guanosine; Humans; Purine Nucleosides; Ribavirin; Vidarabine | 1991 |
57 other study(ies) available for ribavirin and guanosine
Article | Year |
---|---|
Activity of ribavirin against Hantaan virus correlates with production of ribavirin-5'-triphosphate, not with inhibition of IMP dehydrogenase.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Guanosine; Guanosine Triphosphate; Hantaan virus; IMP Dehydrogenase; Mycophenolic Acid; Nucleotides; Ribavirin; RNA, Viral; Time Factors; Vero Cells; Virus Replication | 2007 |
In vitro inhibition of subacute sclerosing panencephalitis virus by the antiviral agent ribavirin.
Topics: Adenosine; Antiviral Agents; Epitopes; Guanosine; Measles virus; Microbial Sensitivity Tests; Ribavirin; Ribonucleosides; SSPE Virus; Viral Plaque Assay | 1978 |
Mechanism and specificity of action of ribavirin.
Topics: Animals; Cell Line; Dogs; Guanosine; Influenza A virus; Inosine; Kidney; Protein Biosynthesis; Ribavirin; Ribonucleosides; Uridine; Viral Proteins | 1979 |
Inhibition of vaccinia virus growth by the nucleoside analogue 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ribavirin).
Topics: Cell Line; Cytoplasm; Deoxyribonucleases; DNA, Viral; Drug Antagonism; Guanosine; Peptide Biosynthesis; Ribavirin; Ribonucleosides; Vaccinia virus; Viral Proteins; Virus Replication | 1976 |
Synthesis and biological activity of some nucleosides resembling guanosine: imidazo(1,2-alpha)pyrimidine nucleosides.
Topics: Guanosine; Imidazoles; Magnetic Resonance Spectroscopy; Methods; Molecular Conformation; Optical Rotation; Pyrimidine Nucleosides; Ribavirin; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1975 |
Inhibition of the replication of influenza A and B viruses by a nucleoside analogue (ribavirin).
Topics: Antigens, Viral; Culture Techniques; Dose-Response Relationship, Drug; Guanosine; Nucleosides; Orthomyxoviridae; Peptide Biosynthesis; Ribavirin; Ribonucleosides; RNA, Viral; Viral Proteins; Virus Replication; Xanthines | 1975 |
Proliferation-linked regulation of type II IMP dehydrogenase gene in human normal lymphocytes and HL-60 leukemic cells.
Topics: Blotting, Northern; Cell Division; Dimethyl Sulfoxide; Gene Expression; Guanosine; Humans; IMP Dehydrogenase; Leukemia, Myeloid; Lymphocyte Activation; Lymphocytes; Ribavirin; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1992 |
IMP dehydrogenase inhibitors reduce intracellular tetrahydrobiopterin levels through reduction of intracellular GTP levels. Indications of the regulation of GTP cyclohydrolase I activity by restriction of GTP availability in the cells.
Topics: Animals; Antineoplastic Agents; Biopterins; GTP Cyclohydrolase; Guanine; Guanosine; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Kinetics; Mycophenolic Acid; Neuroblastoma; PC12 Cells; Ribavirin; Thiadiazoles; Tumor Cells, Cultured | 1992 |
Potentiating effect of ribavirin on the anti-herpes activity of acyclovir.
Topics: Acyclovir; Animals; Cells, Cultured; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Guanosine; Herpesvirus 1, Suid; Keratitis, Herpetic; Rabbits; Ribavirin; Simplexvirus | 1991 |
Cell differentiation and altered IMP dehydrogenase expression induced in human T-lymphoblastoid leukemia cells by mycophenolic acid and tiazofurin.
Topics: Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Survival; Gene Expression; Guanosine; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Leukemia-Lymphoma, Adult T-Cell; Mycophenolic Acid; Ribavirin; Ribonucleosides; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Synergistic action of tiazofurin and retinoic acid on differentiation and colony formation of HL-60 leukemia cells.
Topics: Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Dose-Response Relationship, Drug; Drug Synergism; Guanosine; Humans; IMP Dehydrogenase; Leukemia, Promyelocytic, Acute; Molecular Structure; Phenotype; Ribavirin; Ribonucleosides; Time Factors; Tretinoin; Tumor Cells, Cultured | 1990 |
Induction of cell differentiation in melanoma cells by inhibitors of IMP dehydrogenase: altered patterns of IMP dehydrogenase expression and activity.
Topics: Biomarkers; Gene Expression Regulation, Neoplastic; Guanosine; Humans; IMP Dehydrogenase; Melanins; Melanoma; Monophenol Monooxygenase; Mycophenolic Acid; Neoplasm Proteins; Ribavirin; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1990 |
Expression of memory to the terminal differentiation inducing activity of tiazofurin in HL-60 leukemia cells.
Topics: Antimetabolites, Antineoplastic; Cell Cycle; Cell Differentiation; Cell Line; Cycloheximide; DNA Replication; DNA, Neoplasm; Guanosine; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Ribavirin; Ribonucleotides; Thymidine; Tretinoin | 1991 |
Clinical and molecular impact of inhibition of IMP dehydrogenase activity by tiazofurin.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Differentiation; Cell Division; Cell Line; Guanosine; Humans; IMP Dehydrogenase; Ketone Oxidoreductases; Leukemia, Promyelocytic, Acute; Liver Neoplasms, Experimental; Rats; Ribavirin; Ribonucleosides; Tretinoin; Tumor Cells, Cultured | 1989 |
Effects of the inhibitors of IMP dehydrogenase, tiazofurin and mycophenolic acid, on glycoprotein metabolism.
Topics: Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Glucosamine; Glycoproteins; Guanosine; Guanosine Triphosphate; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Mannose; Mycophenolic Acid; Ribavirin; Ribonucleosides; Sarcoma 180; Tritium | 1985 |
Alterations in glycoprotein synthesis and guanosine triphosphate levels associated with the differentiation of HL-60 leukemia cells produced by inhibitors of inosine 5'-phosphate dehydrogenase.
Topics: Cell Cycle; Cell Differentiation; Cell Line; Dolichol Monophosphate Mannose; Glycoproteins; Guanosine; Guanosine Triphosphate; Hematopoiesis; Humans; IMP Dehydrogenase; Ketone Oxidoreductases; Leukemia, Myeloid, Acute; Mycophenolic Acid; Organoselenium Compounds; Phagocytosis; Ribavirin; Ribonucleosides; Selenium | 1986 |
The importance of IMP dehydrogenase inhibition in the broad spectrum antiviral activity of ribavirin and selenazofurin.
Topics: Antiviral Agents; Cell Line; Guanosine; IMP Dehydrogenase; Ketone Oxidoreductases; Organoselenium Compounds; Parainfluenza Virus 3, Human; Ribavirin; Ribonucleosides; Selenium; Vaccinia virus | 1985 |
A role for guanine ribonucleotides in the regulation of myeloid cell maturation.
Topics: Cell Differentiation; Cell Line; Dimethylformamide; Guanine; Guanine Nucleotides; Guanosine; Hematopoiesis; Humans; IMP Dehydrogenase; Leukemia, Myeloid, Acute; Ribavirin; Tretinoin | 1987 |
Ribavirin induced differentiation of murine erythroleukemia cells.
Topics: Benzidines; Cell Differentiation; Cell Line; Friend murine leukemia virus; Globins; Guanine; Guanosine; Leukemia, Erythroblastic, Acute; Mycophenolic Acid; Ribavirin; Ribonucleosides; RNA, Messenger | 1987 |
Use of tiazofurin to enhance the metabolism and cytotoxic activities of analogues of guanine, guanosine, and deoxyguanosine.
Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Deoxyguanosine; Female; Guanine; Guanosine; Guanosine Triphosphate; Hypoxanthine Phosphoribosyltransferase; Ovary; Ribavirin; Ribonucleosides | 1987 |
Mode of action of ribavirin: effect of nucleotide pool alterations on influenza virus ribonucleoprotein synthesis.
Topics: Guanosine; Guanosine Triphosphate; Nucleotides; Orthomyxoviridae; Ribavirin; Ribonucleoproteins; Ribonucleosides; Virus Replication | 1985 |
Studies on the mechanism of action of 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC 286193)--II. Relationship between dose level and biochemical effects in P388 leukemia in vivo.
Topics: Animals; Antineoplastic Agents; Guanosine; Hypoxanthines; IMP Dehydrogenase; Kinetics; Leukemia P388; Leukemia, Experimental; Mice; Niacinamide; Nucleic Acids; Ribavirin; Ribonucleosides; Time Factors | 1982 |
Lack of interference of guanosine with ribavirin aerosol treatment of influenza A infection in mice.
Topics: Aerosols; Animals; Cells, Cultured; Female; Guanosine; Guanosine Monophosphate; Influenza A virus; Injections, Intraperitoneal; Mice; Mice, Inbred Strains; Orthomyxoviridae Infections; Ribavirin; Ribonucleosides | 1981 |
Inhibition of bluetongue and Colorado tick fever orbiviruses by selected antiviral substances.
Topics: 3-Deazauridine; Adenine; Antiviral Agents; Bluetongue virus; Cells, Cultured; Colorado tick fever virus; Guanosine; Reoviridae; Ribavirin | 1981 |
Novel nucleoside inhibitors of guanosine metabolism as antitumor agents.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Division; Cell Line; Clone Cells; Drug Synergism; Formates; Guanosine; Humans; Lung Neoplasms; Purines; Ribavirin; Ribonucleosides | 1984 |
Broad-spectrum synergistic antiviral activity of selenazofurin and ribavirin.
Topics: Antiviral Agents; DNA, Viral; Drug Combinations; Drug Synergism; Guanosine; Organoselenium Compounds; Ribavirin; Ribonucleosides; RNA, Viral; Selenium | 1984 |
IL-3 and ribavirin induce differentiation and growth suppression during long-term treatment of a megakaryocytic leukemia cell line.
Topics: beta-Thromboglobulin; Cell Adhesion Molecules; Cell Differentiation; Cell Division; Growth Inhibitors; Guanosine; Humans; Interleukin-3; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Membrane Glycoproteins; P-Selectin; Phenotype; Platelet Factor 4; Ribavirin; RNA Processing, Post-Transcriptional; RNA, Messenger; Thrombospondins; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Eicar (5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide). A novel potent inhibitor of inosinate dehydrogenase activity and guanylate biosynthesis.
Topics: Adenosine; Animals; Antineoplastic Agents; Cell Division; Deoxyguanine Nucleotides; Guanine; Guanosine; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Leukemia L1210; Lymphocytes; Mice; Mycophenolic Acid; Purine Nucleotides; Ribavirin; Ribonucleosides; Ribonucleotides; Tumor Cells, Cultured | 1993 |
Tiazofurin decreases Ras-GTP complex in K562 cells.
Topics: Antimetabolites, Antineoplastic; Cell Differentiation; Guanosine; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Oncogene Protein p21(ras); Protein Binding; Ribavirin; Tumor Cells, Cultured | 1993 |
Comparative inhibitory effects of various nucleoside and nonnucleoside analogues on replication of influenza virus types A and B in vitro and in ovo.
Topics: Adenosine; Animals; Antiviral Agents; Benzamidines; Cells, Cultured; Chick Embryo; Dextran Sulfate; Dose-Response Relationship, Drug; Esters; Gabexate; Guanidines; Guanosine; Influenza A virus; Influenza B virus; Nucleosides; Protease Inhibitors; Ribavirin; Virus Replication | 1993 |
[Search for microorganisms among collectable bacterial strains capable of transforming nucleosides into virazole].
Topics: Adenosine; Antiviral Agents; Bacteria; Chromatography, Thin Layer; Culture Media; Guanosine; Hydrolysis; Inosine; Purine-Nucleoside Phosphorylase; Ribavirin; Ribose; Solutions; Spectrophotometry, Ultraviolet | 1998 |
Inhibition of Borna disease virus replication by ribavirin.
Topics: Adenosine; Animals; Antiviral Agents; Borna disease virus; Cell Line; Guanosine; Guanosine Triphosphate; Humans; Neuroglia; Oligodendroglia; Rats; Ribavirin; Virus Replication | 1999 |
Broad-spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: a comparison with ribavirin and demonstration of antiviral additivity with alpha interferon.
Topics: Animals; Antiviral Agents; Carbamates; Cattle; Cell Line; Cytopathogenic Effect, Viral; Electrophoresis; Enzyme Inhibitors; Fibroblasts; Guanosine; Humans; IMP Dehydrogenase; Interferon-alpha; Mice; Molecular Weight; Phenylurea Compounds; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; Signal Transduction; Viral Plaque Assay; Virus Replication; Viruses | 2000 |
Ribavirin and mycophenolic acid potentiate the activity of guanine- and diaminopurine-based nucleoside analogues against hepatitis B virus.
Topics: Acyclovir; Antiviral Agents; Cell Line; Dideoxynucleosides; Dioxolanes; Drug Synergism; Filaggrin Proteins; Guanine; Guanosine; Hepatitis B; Hepatitis B virus; Humans; Mycophenolic Acid; Purine Nucleosides; Ribavirin; Virus Replication | 2000 |
Ribavirin induces error-prone replication of GB virus B in primary tamarin hepatocytes.
Topics: Animals; Antiviral Agents; Cells, Cultured; Disease Models, Animal; Flaviviridae; Guanosine; Hepatitis, Viral, Animal; Hepatocytes; Mycophenolic Acid; Polymerase Chain Reaction; Ribavirin; RNA, Viral; Saguinus; Virus Replication | 2001 |
The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA.
Topics: Antimetabolites; Carbamates; Cell Line, Transformed; Enzyme Inhibitors; Genome, Viral; Guanosine; Hepacivirus; Humans; IMP Dehydrogenase; Mutation; Mycophenolic Acid; Phenylurea Compounds; Replicon; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; RNA; RNA, Viral; Transfection; Virus Replication | 2003 |
Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis.
Topics: Animals; Antiviral Agents; Cell Line; Cricetinae; Foot-and-Mouth Disease Virus; Guanosine; Kidney; Mutagenesis; Mycophenolic Acid; Ribavirin; Virus Replication | 2003 |
Mycophenolic acid inhibits avian reovirus replication.
Topics: Animals; Antiviral Agents; Cell Line; Guanosine; Mycophenolic Acid; Orthoreovirus, Avian; Quail; Ribavirin; Virus Replication | 2004 |
Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap.
Topics: Animals; Antiviral Agents; Binding Sites; Biological Transport; Cell Line, Tumor; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Eukaryotic Initiation Factor-4E; Guanosine; Humans; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Mice; Models, Chemical; Models, Molecular; NIH 3T3 Cells; Protein Binding; Protein Biosynthesis; Ribavirin; RNA Caps; RNA, Messenger; Time Factors | 2004 |
Genetic analysis and functional characterization of polymorphisms in the human concentrative nucleoside transporter, CNT2.
Topics: Alleles; Animals; Antiviral Agents; Cytoplasm; DNA; Dose-Response Relationship, Drug; Exons; Genetic Variation; Guanosine; Haplotypes; Humans; Inhibitory Concentration 50; Inosine; Kinetics; Membrane Transport Proteins; Models, Genetic; Nucleoside Transport Proteins; Nucleosides; Oocytes; Plasmids; Polymorphism, Genetic; Ribavirin; Sensitivity and Specificity; Uridine; Xenopus laevis | 2005 |
Ribavirin is not a functional mimic of the 7-methyl guanosine mRNA cap.
Topics: Antiviral Agents; Eukaryotic Initiation Factor-4E; Guanosine; Molecular Mimicry; Protein Biosynthesis; Recombinant Proteins; Ribavirin; RNA Caps; RNA, Messenger | 2005 |
[Application of tiazofurin in the study of regulation of AMP deaminase in intact malignant cells].
Topics: AMP Deaminase; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Guanosine; Guanosine Triphosphate; Liver Neoplasms, Experimental; Mice; Rats; Rats, Sprague-Dawley; Ribavirin; Tumor Cells, Cultured | 2002 |
The antiviral drug ribavirin does not mimic the 7-methylguanosine moiety of the mRNA cap structure in vitro.
Topics: Antiviral Agents; Guanosine; In Vitro Techniques; Molecular Structure; Protein Biosynthesis; Reference Standards; Ribavirin; RNA Caps; RNA, Messenger | 2005 |
Synthesis of 1-beta-D-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Female; Genome, Viral; Guanosine; Guanosine Triphosphate; Hemorrhagic Fever with Renal Syndrome; Humans; Mice; Mice, Inbred Strains; Mutation; Nucleosides; Orthohantavirus; Ribavirin; Triazoles; Vero Cells | 2008 |
Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes.
Topics: Adult; Aged; Arabinofuranosyluracil; Bile; Cell Culture Techniques; Cell Membrane; Cells, Cultured; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Female; Formycins; Guanosine; Hepatocytes; Humans; Male; Membrane Transport Proteins; Middle Aged; Nucleosides; Ribavirin; RNA, Messenger; Thymidine | 2008 |
Ribavirin potentiates interferon action by augmenting interferon-stimulated gene induction in hepatitis C virus cell culture models.
Topics: Drug Synergism; Guanosine; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon Regulatory Factor-7; Interferon-alpha; Interferon-Stimulated Gene Factor 3, gamma Subunit; NF-kappa B; Oxidoreductases Acting on CH-CH Group Donors; Polyethylene Glycols; Proteins; Recombinant Proteins; Ribavirin; Tumor Cells, Cultured | 2011 |
Mechanism of action of ribavirin in a novel hepatitis C virus replication cell system.
Topics: Antiviral Agents; Cell Division; Cell Line, Tumor; Genotype; Guanosine; Hepacivirus; Humans; IMP Dehydrogenase; Interferons; Oxidative Stress; Ribavirin; RNA, Viral; Signal Transduction; Virus Replication | 2011 |
Complete genome sequence of Bacillus amyloliquefaciens TA208, a strain for industrial production of guanosine and ribavirin.
Topics: Bacillus; Genome, Bacterial; Guanosine; Molecular Sequence Data; Ribavirin | 2011 |
Depletion of GTP pool is not the predominant mechanism by which ribavirin exerts its antiviral effect on Lassa virus.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Ebolavirus; Guanosine; Guanosine Triphosphate; IMP Dehydrogenase; Lassa virus; Mycophenolic Acid; Ribavirin; Ribonucleosides; Vero Cells; Virus Replication | 2011 |
Inhibitory effect of a nucleotide analog on infectious salmon anemia virus infection.
Topics: Animals; Antiviral Agents; Cells, Cultured; Fish Diseases; Fluorescent Antibody Technique; Guanosine; Inhibitory Concentration 50; Isavirus; Orthomyxoviridae Infections; Polymerase Chain Reaction; Polyribosomes; Ribavirin; RNA, Messenger; RNA, Viral; Salmo salar; Virus Replication | 2011 |
Cloning and characterization of purine nucleoside phosphorylase in Escherichia coli and subsequent ribavirin biosynthesis using immobilized recombinant cells.
Topics: Agar; Biocatalysis; Cells, Immobilized; Cloning, Molecular; Escherichia coli; Escherichia coli Proteins; Gels; Genes, Bacterial; Guanosine; Hydrogen-Ion Concentration; Kinetics; Purine-Nucleoside Phosphorylase; Recombinant Fusion Proteins; Ribavirin; Substrate Specificity; Temperature; Triazoles | 2011 |
DNA interaction studies of a platinum (II) complex containing an antiviral drug, ribavirin: the effect of metal on DNA binding.
Topics: Absorption; Animals; Antiviral Agents; Binding Sites; Cattle; Circular Dichroism; DNA; Electrons; Guanosine; Kinetics; Platinum; Ribavirin; Spectrometry, Fluorescence; Temperature; Viscosity | 2012 |
Generation and characterization of influenza A viruses with altered polymerase fidelity.
Topics: Adenosine; Animals; Antiviral Agents; Drug Resistance, Viral; Female; Genetic Variation; Guanosine; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Lung; Mice; Mice, Inbred BALB C; Mutation; Orthomyxoviridae Infections; Reassortant Viruses; Ribavirin; RNA-Dependent RNA Polymerase; Survival Analysis; Viral Proteins; Viral Tropism | 2014 |
Cross Talk between Nucleotide Synthesis Pathways with Cellular Immunity in Constraining Hepatitis E Virus Replication.
Topics: Antiviral Agents; Cell Line, Tumor; Guanosine; Hepatitis E virus; Humans; Immunity, Cellular; IMP Dehydrogenase; Interferon-alpha; Mycophenolic Acid; Nucleotides; Ribavirin; Uridine; Virus Replication | 2016 |
The IMPDH inhibitors, ribavirin and mycophenolic acid, inhibit peste des petits ruminants virus infection.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Drug Synergism; Drug Therapy, Combination; Guanosine; Mycophenolic Acid; Peste-des-Petits-Ruminants; Peste-des-petits-ruminants virus; Ribavirin; Vero Cells; Virus Replication | 2018 |
Ribavirin Induces Polyamine Depletion via Nucleotide Depletion to Limit Virus Replication.
Topics: Acetyltransferases; Cell Line, Tumor; Guanosine; HEK293 Cells; Humans; Interferon Type I; Nucleotides; Polyamines; Ribavirin; Transcription, Genetic; Virus Replication | 2019 |
Inhibitions of human parainfluenza virus type 2 replication by ribavirin and mycophenolate mofetil are restored by guanosine and S-(4-nitrobenzyl)-6-thioinosine.
Topics: Animals; Antiviral Agents; Cell Line; Guanosine; Macaca mulatta; Mycophenolic Acid; Parainfluenza Virus 2, Human; Ribavirin; RNA, Viral; Thioinosine; Virus Internalization; Virus Replication | 2019 |