Page last updated: 2024-08-16

ribavirin and guanosine

ribavirin has been researched along with guanosine in 58 studies

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-199018 (31.03)18.7374
1990's14 (24.14)18.2507
2000's14 (24.14)29.6817
2010's12 (20.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chu, YK; Chung, DH; Jonsson, CB; Parker, WB; Sun, Y1
Murphy, MF1
Browne, MJ1
Katz, E; Margalith, E; Winer, B1
Revankar, GR; Robins, RK1
Oxford, JS1
Nagai, M; Natsumeda, Y; Weber, G1
Harada, T; Hatakeyama, K; Kagamiyama, H1
Pancheva, SN1
Plunkett, W; Saunders, PP1
Collart, FR; Henning-Chubb, C; Huberman, E; Kiguchi, K2
Irino, S; Natsumeda, Y; Weber, G; Yamada, Y; Yamaji, Y1
Sartorelli, AC; Sokoloski, JA2
Hoffman, R; Jayaram, HN; Lapis, E; Natsumeda, Y; Olah, E; Prajda, N; Tricot, GJ; Weber, G; Yamaji, Y; Zhen, WN1
Blair, OC; Sartorelli, AC; Sokoloski, JA1
Kirsi, JJ; McKernan, PA; Murray, BK; North, JA; Revankar, GR; Robins, RK1
Wright, DG1
Kerr, SJ1
Robins, RK; Saunders, PP; Spindler, CD; Tan, MT1
Gilbert, BE; Knight, V; Noall, MW; Wray, SK1
Cooney, DA; Glazer, RI; Jayaram, HN; Johns, DG; Smith, AL1
Alling, DW; Knight, V; Longoria, RM; Moore, RV; Wilson, SZ1
Barnett, BB; Clark, SM; Sidwell, RW; Smee, DF; Spendlove, RS1
Boyd, VL; Jacobsen, SJ; Mangum, JH; Nyhan, WL; Page, TT; Robins, RK; Smejkal, RM1
Burns, NJ; Kirsi, JJ; McKernan, PA; Murray, BK; North, JA; Robins, RK1
Beckstead, JH; Kerby, S; Majumdar, A; Mullikin, B; Seidman, MM; Stenberg, PE1
Balzarini, J; Bohman, C; De Clercq, E; Fridland, A; Herdewijn, P; Horská, K; Karlsson, A; Van Aerschot, A; Votruba, I; Wang, L1
Hata, Y; Natsumeda, Y; Weber, G1
De Clercq, E; Hosoya, M; Ishii, T; Shigeta, S; Suzuki, H1
Iakovleva, EP; Mosunova, TV1
Averett, DR; Briese, T; Jordan, I; Lipkin, WI1
Jain, J; Kwong, AD; Markland, W; McQuaid, TJ1
De Clercq, E; Neyts, J; Ying, C1
Beames, B; Brasky, KM; Chavez, D; Guerra, B; Hong, Z; Lanford, RE; Lau, JY1
Baroudy, BM; Liu, R; Malcolm, BA; Reyes, GR; Zhou, S1
Airaksinen, A; Domingo, E; Menéndez-Arias, L; Pariente, N1
Coombs, KM; Hermann, LL; Robertson, CM1
Borden, KL; Culjkovic, B; Kentsis, A; Shao, L; Topisirovic, I1
Carlson, EJ; Ferrin, TE; Giacomini, KM; Gray, JH; Huang, CC; Johns, SJ; Kawamoto, M; Owen, RP; Stryke, D; Taylor, TR1
Bisaillon, M; Lee, JM; Pelletier, J; Svitkin, Y; Yan, Y1
Bajin-Katić, K; Kovacević, Z; Oros, J1
Beeren, L; Darzynkiewicz, E; Grudzien, E; Jemielity, J; Preiss, T; Rhoads, RE; Stepinski, J; Stolarski, R; Westman, B; Worch, R; Zuberek, J1
Arterburn, JB; Chu, YK; Chung, DH; Jonsson, CB; Kumarapperuma, SC; Li, Q; Parker, WB; Ramanathan, HN; Schmaljohn, CS; Smith, J; Spik, K; Sun, Y1
Endres, CJ; Govindarajan, R; LeCluyse, E; Pastor-Anglada, M; Tse, CM; Unadkat, JD; Whittington, D1
Feld, JJ; Fried, MW; Hu, Z; Li, Q; Liang, TJ; Thomas, E1
Ariumi, Y; Dansako, H; Ikeda, M; Kato, N; Mori, K; Wakita, T1
Chen, N; Deng, A; Liang, Y; Wen, T; Xu, Q; Zhang, G1
Günther, S; Neyts, J; Ölschläger, S1
Cortez-San Martin, M; Mora, P; Reyes-Lopez, F; Rivas-Aravena, A; Sandino, AM; Spencer, E; Tello, M; Vallejos-Vidal, E1
Cai, J; Cen, P; Huang, L; Liu, Y; Luo, W; Xu, Z; Zhao, W; Zhu, X1
Mirzaei kalar, Z; Moghadam, NH; Shahabadi, N1
Cheung, PP; Choy, KT; Fun Sia, S; Guan, Y; Kellam, P; Malik Peiris, JS; Poon, LL; Watson, SJ; Wong, DD; Yen, HL1
Felczak, K; Metselaar, HJ; Pan, Q; Pankiewicz, KW; Peppelenbosch, MP; Raat, NJ; Shokrollahi, E; Sprengers, D; van der Laan, LJ; Wang, W; Wang, Y; Xu, L; Zhou, X1
Cai, X; Chang, QY; Guo, FC; Li, XR; Ma, XX; Pan, Q; Zhou, JH1
Mastrodomenico, V; Mounce, BC; Tate, PM1
Hirai, K; Kawano, M; Kihira-Nakanishi, S; Komada, H; Nishio, M; O'Brien, M; Sakai-Sugino, K; Tsurudome, M; Uematsu, J; Yamamoto, H1

Reviews

1 review(s) available for ribavirin and guanosine

ArticleYear
Metabolism and action of purine nucleoside analogs.
    Pharmacology & therapeutics, 1991, Volume: 49, Issue:3

    Topics: 2-Chloroadenosine; Adenosine; Cladribine; Deoxyadenosines; Guanine; Guanosine; Humans; Purine Nucleosides; Ribavirin; Vidarabine

1991

Other Studies

57 other study(ies) available for ribavirin and guanosine

ArticleYear
Activity of ribavirin against Hantaan virus correlates with production of ribavirin-5'-triphosphate, not with inhibition of IMP dehydrogenase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Guanosine; Guanosine Triphosphate; Hantaan virus; IMP Dehydrogenase; Mycophenolic Acid; Nucleotides; Ribavirin; RNA, Viral; Time Factors; Vero Cells; Virus Replication

2007
In vitro inhibition of subacute sclerosing panencephalitis virus by the antiviral agent ribavirin.
    The Journal of infectious diseases, 1978, Volume: 138, Issue:2

    Topics: Adenosine; Antiviral Agents; Epitopes; Guanosine; Measles virus; Microbial Sensitivity Tests; Ribavirin; Ribonucleosides; SSPE Virus; Viral Plaque Assay

1978
Mechanism and specificity of action of ribavirin.
    Antimicrobial agents and chemotherapy, 1979, Volume: 15, Issue:6

    Topics: Animals; Cell Line; Dogs; Guanosine; Influenza A virus; Inosine; Kidney; Protein Biosynthesis; Ribavirin; Ribonucleosides; Uridine; Viral Proteins

1979
Inhibition of vaccinia virus growth by the nucleoside analogue 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ribavirin).
    The Journal of general virology, 1976, Volume: 32, Issue:2

    Topics: Cell Line; Cytoplasm; Deoxyribonucleases; DNA, Viral; Drug Antagonism; Guanosine; Peptide Biosynthesis; Ribavirin; Ribonucleosides; Vaccinia virus; Viral Proteins; Virus Replication

1976
Synthesis and biological activity of some nucleosides resembling guanosine: imidazo(1,2-alpha)pyrimidine nucleosides.
    Annals of the New York Academy of Sciences, 1975, Aug-08, Volume: 255

    Topics: Guanosine; Imidazoles; Magnetic Resonance Spectroscopy; Methods; Molecular Conformation; Optical Rotation; Pyrimidine Nucleosides; Ribavirin; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1975
Inhibition of the replication of influenza A and B viruses by a nucleoside analogue (ribavirin).
    The Journal of general virology, 1975, Volume: 28, Issue:3

    Topics: Antigens, Viral; Culture Techniques; Dose-Response Relationship, Drug; Guanosine; Nucleosides; Orthomyxoviridae; Peptide Biosynthesis; Ribavirin; Ribonucleosides; RNA, Viral; Viral Proteins; Virus Replication; Xanthines

1975
Proliferation-linked regulation of type II IMP dehydrogenase gene in human normal lymphocytes and HL-60 leukemic cells.
    Cancer research, 1992, Jan-15, Volume: 52, Issue:2

    Topics: Blotting, Northern; Cell Division; Dimethyl Sulfoxide; Gene Expression; Guanosine; Humans; IMP Dehydrogenase; Leukemia, Myeloid; Lymphocyte Activation; Lymphocytes; Ribavirin; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1992
IMP dehydrogenase inhibitors reduce intracellular tetrahydrobiopterin levels through reduction of intracellular GTP levels. Indications of the regulation of GTP cyclohydrolase I activity by restriction of GTP availability in the cells.
    The Journal of biological chemistry, 1992, Oct-15, Volume: 267, Issue:29

    Topics: Animals; Antineoplastic Agents; Biopterins; GTP Cyclohydrolase; Guanine; Guanosine; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Kinetics; Mycophenolic Acid; Neuroblastoma; PC12 Cells; Ribavirin; Thiadiazoles; Tumor Cells, Cultured

1992
Potentiating effect of ribavirin on the anti-herpes activity of acyclovir.
    Antiviral research, 1991, Volume: 16, Issue:2

    Topics: Acyclovir; Animals; Cells, Cultured; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Guanosine; Herpesvirus 1, Suid; Keratitis, Herpetic; Rabbits; Ribavirin; Simplexvirus

1991
Cell differentiation and altered IMP dehydrogenase expression induced in human T-lymphoblastoid leukemia cells by mycophenolic acid and tiazofurin.
    Experimental cell research, 1990, Volume: 187, Issue:1

    Topics: Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Survival; Gene Expression; Guanosine; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Leukemia-Lymphoma, Adult T-Cell; Mycophenolic Acid; Ribavirin; Ribonucleosides; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990
Synergistic action of tiazofurin and retinoic acid on differentiation and colony formation of HL-60 leukemia cells.
    Life sciences, 1990, Volume: 46, Issue:6

    Topics: Antineoplastic Agents; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Dose-Response Relationship, Drug; Drug Synergism; Guanosine; Humans; IMP Dehydrogenase; Leukemia, Promyelocytic, Acute; Molecular Structure; Phenotype; Ribavirin; Ribonucleosides; Time Factors; Tretinoin; Tumor Cells, Cultured

1990
Induction of cell differentiation in melanoma cells by inhibitors of IMP dehydrogenase: altered patterns of IMP dehydrogenase expression and activity.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1990, Volume: 1, Issue:6

    Topics: Biomarkers; Gene Expression Regulation, Neoplastic; Guanosine; Humans; IMP Dehydrogenase; Melanins; Melanoma; Monophenol Monooxygenase; Mycophenolic Acid; Neoplasm Proteins; Ribavirin; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1990
Expression of memory to the terminal differentiation inducing activity of tiazofurin in HL-60 leukemia cells.
    Leukemia research, 1991, Volume: 15, Issue:5

    Topics: Antimetabolites, Antineoplastic; Cell Cycle; Cell Differentiation; Cell Line; Cycloheximide; DNA Replication; DNA, Neoplasm; Guanosine; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Ribavirin; Ribonucleotides; Thymidine; Tretinoin

1991
Clinical and molecular impact of inhibition of IMP dehydrogenase activity by tiazofurin.
    Advances in enzyme regulation, 1989, Volume: 28

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Differentiation; Cell Division; Cell Line; Guanosine; Humans; IMP Dehydrogenase; Ketone Oxidoreductases; Leukemia, Promyelocytic, Acute; Liver Neoplasms, Experimental; Rats; Ribavirin; Ribonucleosides; Tretinoin; Tumor Cells, Cultured

1989
Effects of the inhibitors of IMP dehydrogenase, tiazofurin and mycophenolic acid, on glycoprotein metabolism.
    Molecular pharmacology, 1985, Volume: 28, Issue:6

    Topics: Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Glucosamine; Glycoproteins; Guanosine; Guanosine Triphosphate; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Mannose; Mycophenolic Acid; Ribavirin; Ribonucleosides; Sarcoma 180; Tritium

1985
Alterations in glycoprotein synthesis and guanosine triphosphate levels associated with the differentiation of HL-60 leukemia cells produced by inhibitors of inosine 5'-phosphate dehydrogenase.
    Cancer research, 1986, Volume: 46, Issue:5

    Topics: Cell Cycle; Cell Differentiation; Cell Line; Dolichol Monophosphate Mannose; Glycoproteins; Guanosine; Guanosine Triphosphate; Hematopoiesis; Humans; IMP Dehydrogenase; Ketone Oxidoreductases; Leukemia, Myeloid, Acute; Mycophenolic Acid; Organoselenium Compounds; Phagocytosis; Ribavirin; Ribonucleosides; Selenium

1986
The importance of IMP dehydrogenase inhibition in the broad spectrum antiviral activity of ribavirin and selenazofurin.
    Advances in enzyme regulation, 1985, Volume: 24

    Topics: Antiviral Agents; Cell Line; Guanosine; IMP Dehydrogenase; Ketone Oxidoreductases; Organoselenium Compounds; Parainfluenza Virus 3, Human; Ribavirin; Ribonucleosides; Selenium; Vaccinia virus

1985
A role for guanine ribonucleotides in the regulation of myeloid cell maturation.
    Blood, 1987, Volume: 69, Issue:1

    Topics: Cell Differentiation; Cell Line; Dimethylformamide; Guanine; Guanine Nucleotides; Guanosine; Hematopoiesis; Humans; IMP Dehydrogenase; Leukemia, Myeloid, Acute; Ribavirin; Tretinoin

1987
Ribavirin induced differentiation of murine erythroleukemia cells.
    Molecular and cellular biochemistry, 1987, Volume: 77, Issue:2

    Topics: Benzidines; Cell Differentiation; Cell Line; Friend murine leukemia virus; Globins; Guanine; Guanosine; Leukemia, Erythroblastic, Acute; Mycophenolic Acid; Ribavirin; Ribonucleosides; RNA, Messenger

1987
Use of tiazofurin to enhance the metabolism and cytotoxic activities of analogues of guanine, guanosine, and deoxyguanosine.
    Cancer research, 1987, Feb-15, Volume: 47, Issue:4

    Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Deoxyguanosine; Female; Guanine; Guanosine; Guanosine Triphosphate; Hypoxanthine Phosphoribosyltransferase; Ovary; Ribavirin; Ribonucleosides

1987
Mode of action of ribavirin: effect of nucleotide pool alterations on influenza virus ribonucleoprotein synthesis.
    Antiviral research, 1985, Volume: 5, Issue:1

    Topics: Guanosine; Guanosine Triphosphate; Nucleotides; Orthomyxoviridae; Ribavirin; Ribonucleoproteins; Ribonucleosides; Virus Replication

1985
Studies on the mechanism of action of 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC 286193)--II. Relationship between dose level and biochemical effects in P388 leukemia in vivo.
    Biochemical pharmacology, 1982, Dec-01, Volume: 31, Issue:23

    Topics: Animals; Antineoplastic Agents; Guanosine; Hypoxanthines; IMP Dehydrogenase; Kinetics; Leukemia P388; Leukemia, Experimental; Mice; Niacinamide; Nucleic Acids; Ribavirin; Ribonucleosides; Time Factors

1982
Lack of interference of guanosine with ribavirin aerosol treatment of influenza A infection in mice.
    Antimicrobial agents and chemotherapy, 1981, Volume: 20, Issue:4

    Topics: Aerosols; Animals; Cells, Cultured; Female; Guanosine; Guanosine Monophosphate; Influenza A virus; Injections, Intraperitoneal; Mice; Mice, Inbred Strains; Orthomyxoviridae Infections; Ribavirin; Ribonucleosides

1981
Inhibition of bluetongue and Colorado tick fever orbiviruses by selected antiviral substances.
    Antimicrobial agents and chemotherapy, 1981, Volume: 20, Issue:4

    Topics: 3-Deazauridine; Adenine; Antiviral Agents; Bluetongue virus; Cells, Cultured; Colorado tick fever virus; Guanosine; Reoviridae; Ribavirin

1981
Novel nucleoside inhibitors of guanosine metabolism as antitumor agents.
    Advances in enzyme regulation, 1984, Volume: 22

    Topics: Adenocarcinoma; Antineoplastic Agents; Cell Division; Cell Line; Clone Cells; Drug Synergism; Formates; Guanosine; Humans; Lung Neoplasms; Purines; Ribavirin; Ribonucleosides

1984
Broad-spectrum synergistic antiviral activity of selenazofurin and ribavirin.
    Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:4

    Topics: Antiviral Agents; DNA, Viral; Drug Combinations; Drug Synergism; Guanosine; Organoselenium Compounds; Ribavirin; Ribonucleosides; RNA, Viral; Selenium

1984
IL-3 and ribavirin induce differentiation and growth suppression during long-term treatment of a megakaryocytic leukemia cell line.
    Journal of cellular physiology, 1995, Volume: 165, Issue:3

    Topics: beta-Thromboglobulin; Cell Adhesion Molecules; Cell Differentiation; Cell Division; Growth Inhibitors; Guanosine; Humans; Interleukin-3; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Membrane Glycoproteins; P-Selectin; Phenotype; Platelet Factor 4; Ribavirin; RNA Processing, Post-Transcriptional; RNA, Messenger; Thrombospondins; Transcription, Genetic; Tumor Cells, Cultured

1995
Eicar (5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide). A novel potent inhibitor of inosinate dehydrogenase activity and guanylate biosynthesis.
    The Journal of biological chemistry, 1993, Nov-25, Volume: 268, Issue:33

    Topics: Adenosine; Animals; Antineoplastic Agents; Cell Division; Deoxyguanine Nucleotides; Guanine; Guanosine; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Leukemia L1210; Lymphocytes; Mice; Mycophenolic Acid; Purine Nucleotides; Ribavirin; Ribonucleosides; Ribonucleotides; Tumor Cells, Cultured

1993
Tiazofurin decreases Ras-GTP complex in K562 cells.
    Oncology research, 1993, Volume: 5, Issue:4-5

    Topics: Antimetabolites, Antineoplastic; Cell Differentiation; Guanosine; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Oncogene Protein p21(ras); Protein Binding; Ribavirin; Tumor Cells, Cultured

1993
Comparative inhibitory effects of various nucleoside and nonnucleoside analogues on replication of influenza virus types A and B in vitro and in ovo.
    The Journal of infectious diseases, 1993, Volume: 168, Issue:3

    Topics: Adenosine; Animals; Antiviral Agents; Benzamidines; Cells, Cultured; Chick Embryo; Dextran Sulfate; Dose-Response Relationship, Drug; Esters; Gabexate; Guanidines; Guanosine; Influenza A virus; Influenza B virus; Nucleosides; Protease Inhibitors; Ribavirin; Virus Replication

1993
[Search for microorganisms among collectable bacterial strains capable of transforming nucleosides into virazole].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1998, Volume: 43, Issue:4

    Topics: Adenosine; Antiviral Agents; Bacteria; Chromatography, Thin Layer; Culture Media; Guanosine; Hydrolysis; Inosine; Purine-Nucleoside Phosphorylase; Ribavirin; Ribose; Solutions; Spectrophotometry, Ultraviolet

1998
Inhibition of Borna disease virus replication by ribavirin.
    Journal of virology, 1999, Volume: 73, Issue:9

    Topics: Adenosine; Animals; Antiviral Agents; Borna disease virus; Cell Line; Guanosine; Guanosine Triphosphate; Humans; Neuroglia; Oligodendroglia; Rats; Ribavirin; Virus Replication

1999
Broad-spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: a comparison with ribavirin and demonstration of antiviral additivity with alpha interferon.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:4

    Topics: Animals; Antiviral Agents; Carbamates; Cattle; Cell Line; Cytopathogenic Effect, Viral; Electrophoresis; Enzyme Inhibitors; Fibroblasts; Guanosine; Humans; IMP Dehydrogenase; Interferon-alpha; Mice; Molecular Weight; Phenylurea Compounds; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; Signal Transduction; Viral Plaque Assay; Virus Replication; Viruses

2000
Ribavirin and mycophenolic acid potentiate the activity of guanine- and diaminopurine-based nucleoside analogues against hepatitis B virus.
    Antiviral research, 2000, Volume: 48, Issue:2

    Topics: Acyclovir; Antiviral Agents; Cell Line; Dideoxynucleosides; Dioxolanes; Drug Synergism; Filaggrin Proteins; Guanine; Guanosine; Hepatitis B; Hepatitis B virus; Humans; Mycophenolic Acid; Purine Nucleosides; Ribavirin; Virus Replication

2000
Ribavirin induces error-prone replication of GB virus B in primary tamarin hepatocytes.
    Journal of virology, 2001, Volume: 75, Issue:17

    Topics: Animals; Antiviral Agents; Cells, Cultured; Disease Models, Animal; Flaviviridae; Guanosine; Hepatitis, Viral, Animal; Hepatocytes; Mycophenolic Acid; Polymerase Chain Reaction; Ribavirin; RNA, Viral; Saguinus; Virus Replication

2001
The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA.
    Virology, 2003, Jun-05, Volume: 310, Issue:2

    Topics: Antimetabolites; Carbamates; Cell Line, Transformed; Enzyme Inhibitors; Genome, Viral; Guanosine; Hepacivirus; Humans; IMP Dehydrogenase; Mutation; Mycophenolic Acid; Phenylurea Compounds; Replicon; Reverse Transcriptase Polymerase Chain Reaction; Ribavirin; RNA; RNA, Viral; Transfection; Virus Replication

2003
Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis.
    Virology, 2003, Jul-05, Volume: 311, Issue:2

    Topics: Animals; Antiviral Agents; Cell Line; Cricetinae; Foot-and-Mouth Disease Virus; Guanosine; Kidney; Mutagenesis; Mycophenolic Acid; Ribavirin; Virus Replication

2003
Mycophenolic acid inhibits avian reovirus replication.
    Antiviral research, 2004, Volume: 64, Issue:1

    Topics: Animals; Antiviral Agents; Cell Line; Guanosine; Mycophenolic Acid; Orthoreovirus, Avian; Quail; Ribavirin; Virus Replication

2004
Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Dec-28, Volume: 101, Issue:52

    Topics: Animals; Antiviral Agents; Binding Sites; Biological Transport; Cell Line, Tumor; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Eukaryotic Initiation Factor-4E; Guanosine; Humans; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Mice; Models, Chemical; Models, Molecular; NIH 3T3 Cells; Protein Binding; Protein Biosynthesis; Ribavirin; RNA Caps; RNA, Messenger; Time Factors

2004
Genetic analysis and functional characterization of polymorphisms in the human concentrative nucleoside transporter, CNT2.
    Pharmacogenetics and genomics, 2005, Volume: 15, Issue:2

    Topics: Alleles; Animals; Antiviral Agents; Cytoplasm; DNA; Dose-Response Relationship, Drug; Exons; Genetic Variation; Guanosine; Haplotypes; Humans; Inhibitory Concentration 50; Inosine; Kinetics; Membrane Transport Proteins; Models, Genetic; Nucleoside Transport Proteins; Nucleosides; Oocytes; Plasmids; Polymorphism, Genetic; Ribavirin; Sensitivity and Specificity; Uridine; Xenopus laevis

2005
Ribavirin is not a functional mimic of the 7-methyl guanosine mRNA cap.
    RNA (New York, N.Y.), 2005, Volume: 11, Issue:8

    Topics: Antiviral Agents; Eukaryotic Initiation Factor-4E; Guanosine; Molecular Mimicry; Protein Biosynthesis; Recombinant Proteins; Ribavirin; RNA Caps; RNA, Messenger

2005
[Application of tiazofurin in the study of regulation of AMP deaminase in intact malignant cells].
    Glas. Srpska akademija nauka i umetnosti. Odeljenje medicinskih nauka, 2002, Issue:47

    Topics: AMP Deaminase; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Guanosine; Guanosine Triphosphate; Liver Neoplasms, Experimental; Mice; Rats; Rats, Sprague-Dawley; Ribavirin; Tumor Cells, Cultured

2002
The antiviral drug ribavirin does not mimic the 7-methylguanosine moiety of the mRNA cap structure in vitro.
    RNA (New York, N.Y.), 2005, Volume: 11, Issue:10

    Topics: Antiviral Agents; Guanosine; In Vitro Techniques; Molecular Structure; Protein Biosynthesis; Reference Standards; Ribavirin; RNA Caps; RNA, Messenger

2005
Synthesis of 1-beta-D-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus.
    Antiviral research, 2008, Volume: 79, Issue:1

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Female; Genome, Viral; Guanosine; Guanosine Triphosphate; Hemorrhagic Fever with Renal Syndrome; Humans; Mice; Mice, Inbred Strains; Mutation; Nucleosides; Orthohantavirus; Ribavirin; Triazoles; Vero Cells

2008
Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes.
    American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 295, Issue:3

    Topics: Adult; Aged; Arabinofuranosyluracil; Bile; Cell Culture Techniques; Cell Membrane; Cells, Cultured; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Female; Formycins; Guanosine; Hepatocytes; Humans; Male; Membrane Transport Proteins; Middle Aged; Nucleosides; Ribavirin; RNA, Messenger; Thymidine

2008
Ribavirin potentiates interferon action by augmenting interferon-stimulated gene induction in hepatitis C virus cell culture models.
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:1

    Topics: Drug Synergism; Guanosine; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon Regulatory Factor-7; Interferon-alpha; Interferon-Stimulated Gene Factor 3, gamma Subunit; NF-kappa B; Oxidoreductases Acting on CH-CH Group Donors; Polyethylene Glycols; Proteins; Recombinant Proteins; Ribavirin; Tumor Cells, Cultured

2011
Mechanism of action of ribavirin in a novel hepatitis C virus replication cell system.
    Virus research, 2011, Volume: 157, Issue:1

    Topics: Antiviral Agents; Cell Division; Cell Line, Tumor; Genotype; Guanosine; Hepacivirus; Humans; IMP Dehydrogenase; Interferons; Oxidative Stress; Ribavirin; RNA, Viral; Signal Transduction; Virus Replication

2011
Complete genome sequence of Bacillus amyloliquefaciens TA208, a strain for industrial production of guanosine and ribavirin.
    Journal of bacteriology, 2011, Volume: 193, Issue:12

    Topics: Bacillus; Genome, Bacterial; Guanosine; Molecular Sequence Data; Ribavirin

2011
Depletion of GTP pool is not the predominant mechanism by which ribavirin exerts its antiviral effect on Lassa virus.
    Antiviral research, 2011, Volume: 91, Issue:2

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Ebolavirus; Guanosine; Guanosine Triphosphate; IMP Dehydrogenase; Lassa virus; Mycophenolic Acid; Ribavirin; Ribonucleosides; Vero Cells; Virus Replication

2011
Inhibitory effect of a nucleotide analog on infectious salmon anemia virus infection.
    Journal of virology, 2011, Volume: 85, Issue:16

    Topics: Animals; Antiviral Agents; Cells, Cultured; Fish Diseases; Fluorescent Antibody Technique; Guanosine; Inhibitory Concentration 50; Isavirus; Orthomyxoviridae Infections; Polymerase Chain Reaction; Polyribosomes; Ribavirin; RNA, Messenger; RNA, Viral; Salmo salar; Virus Replication

2011
Cloning and characterization of purine nucleoside phosphorylase in Escherichia coli and subsequent ribavirin biosynthesis using immobilized recombinant cells.
    Enzyme and microbial technology, 2011, May-06, Volume: 48, Issue:6-7

    Topics: Agar; Biocatalysis; Cells, Immobilized; Cloning, Molecular; Escherichia coli; Escherichia coli Proteins; Gels; Genes, Bacterial; Guanosine; Hydrogen-Ion Concentration; Kinetics; Purine-Nucleoside Phosphorylase; Recombinant Fusion Proteins; Ribavirin; Substrate Specificity; Temperature; Triazoles

2011
DNA interaction studies of a platinum (II) complex containing an antiviral drug, ribavirin: the effect of metal on DNA binding.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 96

    Topics: Absorption; Animals; Antiviral Agents; Binding Sites; Cattle; Circular Dichroism; DNA; Electrons; Guanosine; Kinetics; Platinum; Ribavirin; Spectrometry, Fluorescence; Temperature; Viscosity

2012
Generation and characterization of influenza A viruses with altered polymerase fidelity.
    Nature communications, 2014, Sep-03, Volume: 5

    Topics: Adenosine; Animals; Antiviral Agents; Drug Resistance, Viral; Female; Genetic Variation; Guanosine; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Lung; Mice; Mice, Inbred BALB C; Mutation; Orthomyxoviridae Infections; Reassortant Viruses; Ribavirin; RNA-Dependent RNA Polymerase; Survival Analysis; Viral Proteins; Viral Tropism

2014
Cross Talk between Nucleotide Synthesis Pathways with Cellular Immunity in Constraining Hepatitis E Virus Replication.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:5

    Topics: Antiviral Agents; Cell Line, Tumor; Guanosine; Hepatitis E virus; Humans; Immunity, Cellular; IMP Dehydrogenase; Interferon-alpha; Mycophenolic Acid; Nucleotides; Ribavirin; Uridine; Virus Replication

2016
The IMPDH inhibitors, ribavirin and mycophenolic acid, inhibit peste des petits ruminants virus infection.
    Veterinary research communications, 2018, Volume: 42, Issue:4

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Drug Synergism; Drug Therapy, Combination; Guanosine; Mycophenolic Acid; Peste-des-Petits-Ruminants; Peste-des-petits-ruminants virus; Ribavirin; Vero Cells; Virus Replication

2018
Ribavirin Induces Polyamine Depletion via Nucleotide Depletion to Limit Virus Replication.
    Cell reports, 2019, Sep-03, Volume: 28, Issue:10

    Topics: Acetyltransferases; Cell Line, Tumor; Guanosine; HEK293 Cells; Humans; Interferon Type I; Nucleotides; Polyamines; Ribavirin; Transcription, Genetic; Virus Replication

2019
Inhibitions of human parainfluenza virus type 2 replication by ribavirin and mycophenolate mofetil are restored by guanosine and S-(4-nitrobenzyl)-6-thioinosine.
    Drug discoveries & therapeutics, 2019, Volume: 13, Issue:6

    Topics: Animals; Antiviral Agents; Cell Line; Guanosine; Macaca mulatta; Mycophenolic Acid; Parainfluenza Virus 2, Human; Ribavirin; RNA, Viral; Thioinosine; Virus Internalization; Virus Replication

2019