Page last updated: 2024-08-16

ribavirin and fluorouracil

ribavirin has been researched along with fluorouracil in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.86)	18.7374
1990's	5 (14.29)	18.2507
2000's	8 (22.86)	29.6817
2010's	19 (54.29)	24.3611
2020's	2 (5.71)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Agrofoglio, LA; Andrei, G; Balzarini, J; Montagu, A; Roy, V; Snoeck, R	1
Balzarini, J; Kraljević Pavelić, S; Leyssen, P; Makuc, D; Mintas, M; Neyts, J; Pavelić, K; Plavec, J; Sedić, M; Stipković Babić, M; Wittine, K	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Andrei, G; Balzarini, J; Głowacka, IE; Piotrowska, DG; Schols, D; Snoeck, R	1
Andrei, G; Kokosza, K; Piotrowska, DG; Schols, D; Snoeck, R	1
Andrei, G; Kraljević Pavelić, S; Makuc, D; Martinović, T; Mintas, M; Pavelić, K; Plavec, J; Schols, D; Snoeck, R; Stipković Babić, M; Wittine, K	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
De Clercq, E; Marquez, VE; Murase, J	1
Dobrynin, IaV; Lichinitser, MR; Lobova, TG; Nikolaeva, TG; Zharkov, SA	1
Prajda, N; Singhal, RL; Weber, G	1
Prajda, N; Weber, G	1
Chisena, CA; Cysyk, RL; Hyman, R; Monks, A	1
Matsuda, A; Minakawa, N	1
de la Torre, JC; Domingo, E; Ly, C; Ruiz-Jarabo, CM	1
Airaksinen, A; Pariente, N; Sierra, S	1
Feigelstock, DA; Mihalik, KB	1
Li, C; Wang, H; Xie, X; Yang, D; Yu, L; Zeng, J; Zhou, G	1
Lauring, AS; Pauly, MD	1
Khatun, A; Kim, WI; Shabir, N; Yoon, KJ	1
Campagnola, G; de Los Santos, T; Diaz-San Segundo, F; Keith, A; Kloc, A; Peersen, O; Rai, DK; Rieder, E; Schafer, EA	1
Abd-Rabou, AA; Bharali, DJ; Mousa, SA	1
Arias, A; Bassi, MR; Meyn, P; Polacek, C; Sempere, RN	1
Cao, L; Gong, Z; Wang, L; Xi, C; Ye, H; Yu, J	1
Han, Q; Hu, Z; Hua, Q; Li, Q; Zhen, L	1
De Fabritiis, S; Di Bonaventura, G; Di Nicola, M; Lupetti, V; Piccirilli, A; Pompilio, A; Porreca, A	1

Reviews

3 review(s) available for ribavirin and fluorouracil

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Antimetabolites reduce the activities of enzymes with short half-lives in addition to inhibiting their specific targets. Advances in experimental medicine and biology, 1994, Volume: 370 Topics: Animals; Antimetabolites, Antineoplastic; Bone Marrow; Cycloheximide; Enzyme Inhibitors; Fluorouracil; Half-Life; Humans; Isoxazoles; Methotrexate; Prodrugs; Purines; Pyrimidines; Ribavirin; Signal Transduction	1994
Action of mutagenic agents and antiviral inhibitors on foot-and-mouth disease virus. Virus research, 2005, Volume: 107, Issue:2 Topics: Animals; Antiviral Agents; Azacitidine; Cell Line; Cricetinae; Fluorouracil; Foot-and-Mouth Disease Virus; Mutagens; Ribavirin	2005

Other Studies

32 other study(ies) available for ribavirin and fluorouracil

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Synthesis of new C5-(1-substituted-1,2,3-triazol-4 or 5-yl)-2'-deoxyuridines and their antiviral evaluation. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Proliferation; Cells, Cultured; Chlorocebus aethiops; Cyclization; Deoxyuridine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Mice; Microbial Sensitivity Tests; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship; T-Lymphocytes; Vero Cells; Viruses	2011
Novel 1,2,4-triazole and imidazole derivatives of L-ascorbic and imino-ascorbic acid: synthesis, anti-HCV and antitumor activity evaluations. Bioorganic & medicinal chemistry, 2012, Jun-01, Volume: 20, Issue:11 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Ascorbic Acid; Cell Line, Tumor; Dogs; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Fibroblasts; Hepacivirus; Humans; Imidazoles; IMP Dehydrogenase; Magnetic Resonance Spectroscopy; Molecular Structure; Triazoles; Virus Replication	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Design, synthesis, antiviral and cytostatic activity of ω-(1H-1,2,3-triazol-1-yl)(polyhydroxy)alkylphosphonates as acyclic nucleotide analogues. Bioorganic & medicinal chemistry, 2014, Jul-15, Volume: 22, Issue:14 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Proliferation; Cell Survival; Cytostatic Agents; DNA Viruses; Dogs; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; HeLa Cells; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Organophosphonates; RNA Viruses; Structure-Activity Relationship; T-Lymphocytes; Triazoles	2014
Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues. Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13 Topics: Acrylamides; Adenine; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Survival; Cycloaddition Reaction; Cytomegalovirus; Cytostatic Agents; Drug Design; Enterovirus; Humans; Isoxazoles; Naphthalimides; Nitrogen Oxides; Organophosphonates; Phlebovirus; Simplexvirus; Structure-Activity Relationship; Vaccinia virus	2015
Novel halogenated 3-deazapurine, 7-deazapurine and alkylated 9-deazapurine derivatives of L-ascorbic or imino-L-ascorbic acid: Synthesis, antitumour and antiviral activity evaluations. European journal of medicinal chemistry, 2015, Sep-18, Volume: 102 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Ascorbic Acid; Cell Line; Cell Proliferation; Cytomegalovirus; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Purines; Structure-Activity Relationship	2015
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Broad-spectrum antiviral and cytocidal activity of cyclopentenylcytosine, a carbocyclic nucleoside targeted at CTP synthetase. Biochemical pharmacology, 1991, Jun-15, Volume: 41, Issue:12 Topics: Adenosine; Amides; Antiviral Agents; Azauridine; Carbon-Nitrogen Ligases; Cell Division; Cytarabine; Cytidine; Deoxycytidine; Drug Synergism; Fluorouracil; HeLa Cells; Humans; Ligases; Nucleosides; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Thymidine; Tumor Cells, Cultured; Uracil; Virus Replication; Viruses	1991
[Ribamidil as a modulator of the toxic effect of 5-fluorouracil]. Eksperimental'naia onkologiia, 1985, Volume: 7, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cells, Cultured; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Ovarian Neoplasms; Ribavirin; Ribonucleosides	1985
Targeted and non-targeted actions of anti-cancer drugs. Advances in enzyme regulation, 1994, Volume: 34 Topics: Animals; Antimetabolites, Antineoplastic; Bone Marrow; Cycloheximide; Deoxycytidine Kinase; Fluorouracil; Hypoxanthine Phosphoribosyltransferase; Isoxazoles; Methotrexate; Neoplasms, Experimental; Pyrimidines; Rats; Rats, Inbred Strains; Ribavirin; Thymidine Kinase; Thymidylate Synthase	1994
Tiazofurin enhances the anabolism and toxicity of 5-fluorouracil. Cancer letters, 1996, Dec-03, Volume: 109, Issue:1-2 Topics: Animals; Antimetabolites, Antineoplastic; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Fluorouracil; Leukemia L1210; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Phosphoribosyl Pyrophosphate; Ribavirin	1996
Mechanism-based design of inosine 5-monophosphate dehydrogenase inhibitors: synthesis and biological activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide (EICAR) and its derivatives. Current medicinal chemistry, 1999, Volume: 6, Issue:7 Topics: Animals; Antineoplastic Agents; Catalysis; Drug Design; Fluorouracil; Humans; IMP Dehydrogenase; Inhibitory Concentration 50; Leukemia L1210; Models, Chemical; Ribavirin; Ribonucleosides; Structure-Activity Relationship; Tumor Cells, Cultured	1999
Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV). Virology, 2003, Mar-30, Volume: 308, Issue:1 Topics: Animals; Antiviral Agents; Arenaviridae Infections; B-Lymphocytes; Cell Line; Cricetinae; DNA-Binding Proteins; Fluorouracil; Gene Expression; Lymphocytic choriomeningitis virus; Mice; Mice, Knockout; Mutagenesis; Receptors, Interferon; Ribavirin; RNA, Viral; T-Lymphocytes; Transfection; Virus Replication	2003
Sensitivity of a ribavirin resistant mutant of hepatitis C virus to other antiviral drugs. PloS one, 2013, Volume: 8, Issue:9 Topics: Amino Acid Substitution; Antiviral Agents; Cell Line; Cytidine; Drug Resistance, Viral; Fluorouracil; Hepacivirus; Hepatitis C, Chronic; Humans; Kinetics; Microbial Sensitivity Tests; Mutation; Ribavirin; Viral Proteins; Virus Replication	2013
Foot-and-mouth disease virus low-fidelity polymerase mutants are attenuated. Archives of virology, 2014, Volume: 159, Issue:10 Topics: Animals; Antiviral Agents; Base Sequence; Cell Line; Cricetinae; Drug Resistance, Viral; Fluorouracil; Foot-and-Mouth Disease; Foot-and-Mouth Disease Virus; Mice; Mice, Inbred BALB C; Mutation; Mutation Rate; Ribavirin; RNA-Dependent RNA Polymerase; RNA, Viral; Sequence Analysis, RNA; Virus Replication	2014
Effective lethal mutagenesis of influenza virus by three nucleoside analogs. Journal of virology, 2015, Volume: 89, Issue:7 Topics: Animals; Azacitidine; Cell Line; Dogs; Drug Resistance, Viral; Fluorouracil; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Microbial Viability; Mutagenesis; Nucleosides; Ribavirin; Serial Passage; Virus Cultivation; Virus Replication	2015
Effects of ribavirin on the replication and genetic stability of porcine reproductive and respiratory syndrome virus. BMC veterinary research, 2015, Feb-07, Volume: 11 Topics: Amiloride; Animals; Antiviral Agents; Azacitidine; Cell Line; Chlorocebus aethiops; Fluorouracil; Genome, Viral; Mutagenesis; Mutagens; Porcine respiratory and reproductive syndrome virus; Ribavirin; Virus Replication	2015
Attenuation of Foot-and-Mouth Disease Virus by Engineered Viral Polymerase Fidelity. Journal of virology, 2017, 08-01, Volume: 91, Issue:15 Topics: Amino Acid Substitution; Animals; Antigens, Viral; Antiviral Agents; Cells, Cultured; Cricetinae; Disease Models, Animal; DNA Mutational Analysis; Drug Resistance, Viral; Fluorouracil; Foot-and-Mouth Disease; Foot-and-Mouth Disease Virus; Mice; Mutagenesis, Site-Directed; Point Mutation; Protein Engineering; Ribavirin; Swine; Tryptophan; Viral Nonstructural Proteins; Viral Plaque Assay	2017
Taribavirin and 5-Fluorouracil-Loaded Pegylated-Lipid Nanoparticle Synthesis, p38 Docking, and Antiproliferative Effects on MCF-7 Breast Cancer. Pharmaceutical research, 2018, Feb-27, Volume: 35, Issue:4 Topics: Antineoplastic Agents; Biological Availability; Breast Neoplasms; Drug Carriers; Drug Compounding; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Inhibitory Concentration 50; Lipids; MCF-7 Cells; Mitogen-Activated Protein Kinase 14; Molecular Docking Simulation; Nanoparticles; Polyethylene Glycols; Ribavirin	2018
Extinction of Zika Virus and Usutu Virus by Lethal Mutagenesis Reveals Different Patterns of Sensitivity to Three Mutagenic Drugs. Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:9 Topics: Amides; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Epithelial Cells; Flavivirus; Fluorouracil; Mutagenesis; Mutagens; Mutation Rate; Nucleosides; Pyrazines; Ribavirin; Ribonucleosides; Serial Passage; Vero Cells; Virus Replication; Zika Virus; Zika Virus Infection	2018
Inhibition of eukaryotic translation initiation factor 4E is effective against chemo-resistance in colon and cervical cancer. Biochemical and biophysical research communications, 2018, 09-18, Volume: 503, Issue:4 Topics: Animals; Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Colonic Neoplasms; Drug Resistance; Drug Synergism; Eukaryotic Initiation Factor-4E; Female; Fluorouracil; Humans; Mice; Paclitaxel; Ribavirin; Uterine Cervical Neoplasms	2018
Ribavirin sensitizes nasopharyngeal carcinoma to 5-fluorouracil through suppressing 5-fluorouracil-induced ERK-dependent-eIF4E activation. Biochemical and biophysical research communications, 2019, 06-11, Volume: 513, Issue:4 Topics: Animals; Cell Line, Tumor; Epithelial Cells; Eukaryotic Initiation Factor-4E; Extracellular Signal-Regulated MAP Kinases; Fluorouracil; Humans; Mice; Nasopharyngeal Carcinoma; Phosphorylation; Proto-Oncogene Proteins c-akt; Ribavirin; Signal Transduction; Xenograft Model Antitumor Assays	2019
Giving Drugs a Second Chance: Antibacterial and Antibiofilm Effects of Ciclopirox and Ribavirin against Cystic Fibrosis International journal of molecular sciences, 2022, Apr-30, Volume: 23, Issue:9 Topics: Anti-Bacterial Agents; Biofilms; Ciclopirox; Cystic Fibrosis; Dactinomycin; Drug Repositioning; Extracellular Polymeric Substance Matrix; Fluorouracil; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Ribavirin; Tobramycin	2022