ribavirin has been researched along with brivudine in 52 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (9.62) | 18.7374 |
1990's | 10 (19.23) | 18.2507 |
2000's | 19 (36.54) | 29.6817 |
2010's | 16 (30.77) | 24.3611 |
2020's | 2 (3.85) | 2.80 |
Authors | Studies |
---|---|
De Clercq, E; Koga, M; Patil, SD; Schneller, SW; Snoeck, R | 1 |
Balzarini, J; De Clercq, E; Hermkens, PH; Kruse, CG; Scheeren, HW; Van Maarseveen, JH | 1 |
Andrei, G; Balzarini, J; De Clercq, E; Hosoya, M; Patil, SD; Schneller, SW; Snoeck, R | 1 |
Baitz-Gács, E; Béres, J; De Clercq, E; Gruber, L; Otvös, L; Sági, G; Tömösközi, I | 1 |
Andrei, G; De Clercq, E; Golankiewicz, B; Ostrowski, T; Snoeck, R | 1 |
Andrei, G; De Clercq, E; Ikeda, S; Otvös, L; Sági, G; Snoeck, R | 1 |
De Clercq, E; Herdewijn, PA; Ikeda, S; Mamos, P; Van Aerschot, AA; Weyns, NJ | 1 |
Andrei, G; Balzarini, J; Blache, Y; Chapat, JP; Chavignon, O; De Clercq, E; Debouzy, JC; Elhakmaoui, A; Essassi, EM; Gueiffier, A; Kerbal, A; Lhassani, M; Snoeck, R; Teulade, JC; Witvrouw, M | 1 |
Balzarini, J; De Clercq, E; Faraj, A; Fedorov, II; Gosselin, G; Gurskaya, GV; Imbach, JL; Jasko, MV; Kazmina, EM; Sommadossi, JP; Zavodnic, VE | 1 |
Schneller, SW; Seley, KL; Wu, J | 1 |
Balboni, G; Balzarini, J; Bando, T; Baraldi, PG; Clercq, ED; Pavani, MG; Romagnoli, R; Spalluto, G; Sugiyama, H; Tabrizi, MA | 1 |
Andrei, G; De Clercq, E; Dimas, K; Foscolos, GB; Fytas, G; Kolocouris, A; Kolocouris, N; Pannecouque, C; Snoeck, R; Stamatiou, G; Witvrouw, M; Zoidis, G | 1 |
Balzarini, J; De Clercq, E; Guenther, S; Nair, V | 1 |
Chiacchio, MA; Corsaro, A; De Clercq, E; Iannazzo, D; Mastino, A; Piperno, A; Rescifina, A; Romeo, G; Romeo, R; Valveri, V | 1 |
Balzarini, J; De Clercq, E; Gazivoda, T; Kralj, M; Marjanović, M; Mintas, M; Pavelić, K; Raić-Malić, S | 1 |
Alvarez, K; Balzarini, J; Barral, K; Canard, B; Neyts, J; Priet, S; Sire, J | 1 |
Andrei, G; Balzarini, J; De Clercq, E; Holý, A; Krecmerová, M; Masojídková, M; Naesens, L; Neyts, J; Pískala, A; Snoeck, R | 1 |
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Andrei, G; Balzarini, J; Cristofoli, WA; De Clercq, E; Knaus, EE; Snoeck, R; Wiebe, LI | 1 |
Balzarini, J; Clercq, ED; Kralj, M; Makuc, D; Mintas, M; Pavelić, K; Plavec, J; Prekupec, S; Raić-Malić, S; Suman, L | 1 |
De Clercq, E; Küçükgüzel, I; Küçükgüzel, SG; Rollas, S; Tatar, E | 1 |
Andrei, G; Balzarini, J; De Clercq, E; Gazivoda, T; Kralj, M; Mintas, M; Pavelić, K; Raić-Malić, S; Snoeck, R; Sokcević, M; Suman, L | 1 |
Andrei, G; Balzarini, J; De Clercq, E; Holý, A; Krecmerová, M; Masojídková, M; Naesens, L; Neyts, J; Pohl, R; Snoeck, R | 1 |
De Clercq, E; Gawin, R; Koszytkowska-Stawińska, M; Naesens, L | 1 |
Balzarini, J; De Clercq, E; Judge, V; Kumar, P; Narang, R; Narasimhan, B; Sharma, D | 1 |
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E | 1 |
Balzarini, J; Brancale, A; Cirilli, R; Coluccia, A; Giordano, C; La Regina, G; La Torre, F; Lavecchia, A; Maga, G; Novellino, E; Piscitelli, F; Samuele, A; Sansone, A; Silvestri, R; Zanoli, S | 1 |
Andrei, G; Bayrak, OF; De Clercq, E; Güniz Küçükgüzel, S; Karakuş, S; Küçükgüzel, I; Pannecouque, C; Sahin, F; Snoeck, R | 1 |
Andrei, G; Balzarini, J; Baraka, MM; el-Sabbagh, OI; Ibrahim, SM; Pannecouque, C; Rashad, AA; Snoeck, R | 1 |
Balzarini, J; Bhargava, A; De Clercq, E; Rai, D; Singh, RK; Yadav, D | 1 |
Asaftei, S; De Clercq, E | 1 |
De Clercq, E; Ganguly, S; Kumar, KS; Veerasamy, R | 1 |
Balzarini, J; De Clercq, E; Dewan, SK; Kumar, P; Narasimhan, B; Pannecouque, C; Yadav, S | 1 |
Agrofoglio, LA; Andrei, G; Balzarini, J; Montagu, A; Roy, V; Snoeck, R | 1 |
Andrei, G; Balzarini, J; Dračínský, M; Holý, A; Krečmerová, M; Snoeck, R; Tichý, T | 1 |
Balzarini, J; Głowacka, IE; Piotrowska, DG | 1 |
Balzarini, J; Bharatam, PV; Chibale, K; Kaur, H; Little, S; Singh, K | 1 |
Batta, G; Bereczki, I; Borbás, A; Fejes, Z; Herczegh, P; Kiss-Szikszai, A; Naesens, L; Ostorházi, E; Rőth, E; Rozgonyi, F; Sipos, A; Török, Z | 1 |
Balzarini, J; Chibale, K; Kaur, H; Singh, K | 1 |
Balzarini, J; Singh, K | 1 |
Andrei, G; Kokosza, K; Piotrowska, DG; Schols, D; Snoeck, R | 1 |
Çapan, G; Cihan-Üstündağ, G; Gürsoy, E; Naesens, L; Ulusoy-Güzeldemirci, N | 1 |
Andrei, G; Pertusati, F; Pileggi, E; Schols, D; Serpi, M; Snoeck, R | 1 |
Andrei, G; Cazin, I; Harej, A; Klobučar, M; Macan, AM; Pavelić, K; Pavelić, SK; Raić-Malić, S; Schols, D; Snoeck, R; Stepanić, V | 1 |
Balzarini, J; De Clercq, E; Karki, SS; Kulkarni, AA; Kumar, S; Veliyath, SK | 1 |
Agard, DA; Ashworth, A; Barrio-Hernandez, I; Batra, J; Beltrao, P; Bennett, MJ; Bohn, M; Bouhaddou, M; Braberg, H; Broadhurst, DJ; Cai, Y; Cakir, M; Calviello, L; Cavero, DA; Chang, JCJ; Chorba, JS; Craik, CS; d'Enfert, C; Dai, SA; Eckhardt, M; Emerman, M; Fabius, JM; Fletcher, SJ; Floor, SN; Foussard, H; Frankel, AD; Fraser, JS; Fujimori, DG; Ganesan, SJ; García-Sastre, A; Gordon, DE; Gross, JD; Guo, JZ; Haas, K; Haas, P; Hernandez-Armenta, C; Hiatt, J; Huang, XP; Hubert, M; Hüttenhain, R; Ideker, T; Jacobson, M; Jang, GM; Jura, N; Kaake, RM; Kim, M; Kirby, IT; Klippsten, S; Koh, C; Kortemme, T; Krogan, NJ; Kuzuoglu-Ozturk, D; Li, Q; Liboy-Lugo, J; Lin, Y; Liu, X; Liu, Y; Lou, K; Lyu, J; Mac Kain, A; Malik, HS; Mathy, CJP; McGregor, MJ; Melnyk, JE; Memon, D; Meyer, B; Miorin, L; Modak, M; Moreno, E; Mukherjee, S; Naing, ZZC; Noack, J; O'Meara, MJ; O'Neal, MC; Obernier, K; Ott, M; Peng, S; Perica, T; Pilla, KB; Polacco, BJ; Rakesh, R; Rathore, U; Rezelj, VV; Richards, AL; Roesch, F; Rosenberg, OS; Rosenthal, SB; Roth, BL; Roth, TL; Ruggero, D; Safari, M; Sali, A; Saltzberg, DJ; Savar, NS; Schwartz, O; Sharp, PP; Shen, W; Shengjuler, D; Shi, Y; Shoichet, BK; Shokat, KM; Soucheray, M; Stroud, RM; Subramanian, A; Swaney, DL; Taunton, J; Tran, QD; Trenker, R; Tummino, TA; Tutuncuoglu, B; Ugur, FS; Vallet, T; Venkataramanan, S; Verba, KA; Verdin, E; Vignuzzi, M; von Zastrow, M; Wang, HY; Wankowicz, SA; Wenzell, NA; White, KM; Xu, J; Young, JM; Zhang, Z; Zhou, Y | 1 |
Andrei, G; Aralov, AV; Belyaev, ES; Chistov, AA; Ishmukhametov, AA; Jegorov, AV; Korshun, VA; Kozlovskaya, LI; Matyugina, ES; Nikolaeva, YV; Osolodkin, DI; Shtro, AA; Snoeck, R; Volok, VP | 1 |
Bryson, YJ | 1 |
Lee, JJ; Lin, TS; Mancini, WR; Otto, MJ; Prusoff, WH; Siegel, SA | 1 |
White, DO | 1 |
de Clercq, E | 1 |
Johansson, NG; Oberg, B | 1 |
5 review(s) available for ribavirin and brivudine
Article | Year |
---|---|
Promising new antiviral drugs.
Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cytomegalovirus Infections; Foscarnet; Ganciclovir; Herpes Simplex; Herpes Zoster; Humans; Interferons; Phosphonoacetic Acid; Ribavirin; Thymidine; Zidovudine | 1988 |
Physical and biological consequences of incorporation of antiviral agents into virus DNA.
Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cytarabine; Dideoxynucleosides; DNA, Viral; Idoxuridine; Protein Biosynthesis; Ribavirin; Simplexvirus; Structure-Activity Relationship; Thymidine; Thymine Nucleotides; Transcription, Genetic; Vidarabine | 1984 |
Antiviral chemotherapy.
Topics: Acyclovir; Amantadine; Animals; Antiviral Agents; Bromodeoxyuridine; Female; Hepatitis B; Herpes Genitalis; Herpes Simplex; Herpes Zoster; Humans; Idoxuridine; In Vitro Techniques; Interferons; Male; Neoplasms; Papillomaviridae; Respiratory Tract Infections; Ribavirin; Rimantadine; Tumor Virus Infections; Vidarabine | 1984 |
Nucleoside analogues as antiviral agents.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Cytarabine; Deoxyuridine; Guanine; Herpesviridae Infections; Humans; Idoxuridine; Nucleosides; Ribavirin; Thymidine; Virus Diseases; Viruses | 1981 |
The relative merits and drawbacks of new nucleoside analogues with clinical potential.
Topics: Acyclovir; Animals; Antiviral Agents; Biotransformation; Bromodeoxyuridine; Cytarabine; DNA-Directed RNA Polymerases; Ganciclovir; Humans; Idoxuridine; Nucleic Acid Synthesis Inhibitors; Nucleic Acids; Nucleosides; Ribavirin; Trifluridine; Vidarabine; Viruses | 1984 |
47 other study(ies) available for ribavirin and brivudine
Article | Year |
---|---|
(+-)-carbocyclic 5'-nor-2'-deoxyguanosine and related purine derivatives: synthesis and antiviral properties.
Topics: 2-Aminopurine; Antiviral Agents; Cytomegalovirus; Deoxyadenosines; Deoxyguanosine; Herpesvirus 3, Human; HIV-1; HIV-2; Molecular Structure; Simplexvirus; Structure-Activity Relationship; Vaccinia virus; Vesicular stomatitis Indiana virus | 1992 |
Antiviral and antitumor structure-activity relationship studies on tetracyclic eudistomines.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Carbolines; HIV; Humans; Leukemia L1210; Leukemia P388; Mice; Molecular Structure; Simplexvirus; Structure-Activity Relationship; T-Lymphocytes; Tumor Cells, Cultured; Urochordata | 1992 |
Synthesis and antiviral properties of (+/-)-5'-noraristeromycin and related purine carbocyclic nucleosides. A new lead for anti-human cytomegalovirus agent design.
Topics: Adenosine; Adenosylhomocysteinase; Antiviral Agents; Cytomegalovirus; Drug Design; Humans; Hydrolases; Purine Nucleosides; Stereoisomerism | 1992 |
Stereospecific synthesis and antiviral properties of different enantiomerically pure carbocyclic 2'-deoxyribonucleoside analogues derived from common chiral pools: (+)-(1R,5S)- and (-)-(1S,5R)-2-oxabicyclo[3.3.0]oct-6-en-3-one.
Topics: Antiviral Agents; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Chemical Phenomena; Chemistry; Microbial Sensitivity Tests; Simplexvirus; Stereoisomerism; Structure-Activity Relationship; Thymidine; Vaccinia virus | 1990 |
Tricyclic analogues of acyclovir and ganciclovir. Influence of substituents in the heterocyclic moiety on the antiviral activity.
Topics: Acyclovir; Antiviral Agents; Ganciclovir; Microbial Sensitivity Tests; Structure-Activity Relationship | 1994 |
Synthesis and antiviral activities of 8-alkynyl-, 8-alkenyl-, and 8-alkyl-2'-deoxyadenosine analogues.
Topics: Adenosylhomocysteinase; Antiviral Agents; Cell Division; Cell Line; Cytomegalovirus; Deoxyadenosines; Embryo, Mammalian; Herpesvirus 3, Human; Humans; Hydrolases; Influenza A virus; Lung; Molecular Structure; Respiratory Syncytial Viruses; Vaccinia virus; Vesicular stomatitis Indiana virus | 1994 |
Antiviral activity of C-alkylated purine nucleosides obtained by cross-coupling with tetraalkyltin reagents.
Topics: Adenosine; Antiviral Agents; Cell Line; Herpesvirus 1, Human; HIV-1; HIV-2; Humans; Indicators and Reagents; Organotin Compounds; Respiratory Syncytial Viruses; Vaccinia virus | 1993 |
Synthesis of acyclo-C-nucleosides in the imidazo[1,2-a]pyridine and pyrimidine series as antiviral agents.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; HeLa Cells; Humans; Nucleosides; Pyridines; Pyrimidines; Structure-Activity Relationship; Tumor Cells, Cultured; Vero Cells | 1996 |
Novel 3'-C/N-substituted 2',3'-beta-D-dideoxynucleosides as potential chemotherapeutic agents. 1. Thymidine derivatives: synthesis, structure, and broad spectrum antiviral properties.
Topics: Antiviral Agents; Crystallography, X-Ray; Dideoxynucleosides; HIV-1; HIV-2; Humans; Isomerism; Models, Chemical; Models, Molecular; Structure-Activity Relationship; Thymidine; Virus Replication | 1997 |
Carbocyclic oxetanocins lacking the C-3' methylene.
Topics: Adenine; Adenosine; Animals; Antiviral Agents; Cells, Cultured; Giant Cells; Guanine; Herpesvirus 1, Human; Herpesvirus 3, Human; HIV-1; HIV-2; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Viruses | 1997 |
Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI) subunit of the antitumor agent CC-1065 and polypyrrole minor groove binders.
Topics: Animals; Antineoplastic Agents, Alkylating; Antiviral Agents; DNA; Drug Design; Drug Screening Assays, Antitumor; Duocarmycins; Humans; Indazoles; Indoles; Leucomycins; Mice; Models, Molecular; Pyrazoles; Pyrroles; Solubility; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured; Water | 2001 |
New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation.
Topics: Bacteria; Cell Division; Cell Line; Formazans; Humans; Hydrazones; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazolium Salts; Thiosemicarbazones; Tumor Cells, Cultured; Viruses | 2002 |
A thymidine phosphorylase-stable analogue of BVDU with significant antiviral activity.
Topics: Antiviral Agents; Binding Sites; Bromodeoxyuridine; Cell Line; Crystallography, X-Ray; Cytomegalovirus; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Humans; Models, Molecular; Stereoisomerism; Structure-Activity Relationship; Thymidine Phosphorylase; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Replication | 2002 |
Synthesis and biological activity of isoxazolidinyl polycyclic aromatic hydrocarbons: potential DNA intercalators.
Topics: Animals; Anthracenes; Antineoplastic Agents; Antiviral Agents; Apoptosis; Cell Line, Tumor; Chlorocebus aethiops; DNA; DNA Viruses; Drug Screening Assays, Antitumor; fas Receptor; Humans; Intercalating Agents; Isoxazoles; Phenanthrenes; Polycyclic Aromatic Hydrocarbons; Pyrenes; RNA Viruses; Stereoisomerism; Structure-Activity Relationship; Vero Cells | 2006 |
The novel C-5 aryl, alkenyl, and alkynyl substituted uracil derivatives of L-ascorbic acid: synthesis, cytostatic, and antiviral activity evaluations.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Ascorbic Acid; Cell Line, Tumor; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Fibroblasts; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Pyrimidines; Structure-Activity Relationship; Uracil; Viruses | 2007 |
Synthesis, in vitro antiviral evaluation, and stability studies of novel alpha-borano-nucleotide analogues of 9-[2-(phosphonomethoxy)ethyl]adenine and (R)-9-[2-(phosphonomethoxy)propyl]adenine.
Topics: Adenine; Animals; Anti-HIV Agents; Antiviral Agents; Boranes; Boron Compounds; Chlorocebus aethiops; DNA Viruses; HIV-1; Humans; In Vitro Techniques; Nucleosides; Organophosphonates; Phosphates; RNA Viruses; Structure-Activity Relationship; Vero Cells; Virus Replication | 2006 |
Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds.
Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cidofovir; Cytosine; DNA Viruses; Humans; Mice; Organophosphonates; Retroviridae; RNA Viruses; Stereoisomerism; Structure-Activity Relationship; Triazines | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells.
Topics: Alkynes; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; Deoxyuridine; Drug Screening Assays, Antitumor; Herpesvirus 3, Human; Humans; Mice; Simplexvirus; Stereoisomerism; Structure-Activity Relationship; Thymidine Kinase; Transfection; Uridine | 2007 |
Novel C-6 fluorinated acyclic side chain pyrimidine derivatives: synthesis, (1)H and (13)C NMR conformational studies, and antiviral and cytostatic evaluations.
Topics: Animals; Antiviral Agents; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; Cytostatic Agents; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Conformation; Molecular Mimicry; Positron-Emission Tomography; Pyrimidine Nucleosides; Pyrimidines; Structure-Activity Relationship | 2007 |
Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents.
Topics: Animals; Antitubercular Agents; Antiviral Agents; Cell Line; Drug Evaluation, Preclinical; Humans; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Thiourea; Triazoles | 2008 |
Synthesis and antiviral and cytostatic evaluations of the new C-5 substituted pyrimidine and furo[2,3-d]pyrimidine 4',5'-didehydro-L-ascorbic acid derivatives.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Ascorbic Acid; Cell Line; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Mice; Pyrimidines; Pyrimidinones; Stereoisomerism; Structure-Activity Relationship | 2007 |
Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: synthesis and antiviral activity.
Topics: Antiviral Agents; Cell Line; Cytosine; DNA Viruses; Drug Resistance, Viral; Esters; Humans; Magnetic Resonance Spectroscopy; Prodrugs; Retroviridae; RNA Viruses; Stereoisomerism; Structure-Activity Relationship | 2007 |
Synthesis and antiviral evaluation of acyclic azanucleosides developed from sulfanilamide as a lead structure.
Topics: Animals; Antiviral Agents; Aza Compounds; Catalysis; Cell Line; DNA Viruses; Drug Resistance, Viral; Humans; Hydrogenation; Nucleosides; Palladium; Pyrimidine Nucleosides; RNA Viruses; Structure-Activity Relationship; Sulfanilamide; Sulfanilamides | 2008 |
Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antiviral Agents; Aspergillus niger; Bacillus subtilis; Candida albicans; Cells, Cultured; Chlorocebus aethiops; Drug Design; Escherichia coli; HeLa Cells; Herpesvirus 1, Human; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship; Vero Cells | 2009 |
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship | 2009 |
Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie B4 virus.
Topics: Amino Acids; Animals; Anti-HIV Agents; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Cytostatic Agents; Drug Resistance, Viral; Enterovirus B, Human; HIV Reverse Transcriptase; HIV-1; Humans; Hydrophobic and Hydrophilic Interactions; Indoles; Lymphocytes; Mice; Models, Molecular; Molecular Conformation; Mutation; Protein Binding; Reverse Transcriptase Inhibitors; Stereoisomerism; Structure-Activity Relationship; Sulfones; Virus Replication | 2009 |
Synthesis, antiviral and anticancer activity of some novel thioureas derived from N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Sulfonamides; Thiourea; Viruses | 2009 |
Synthesis and antiviral activity of new pyrazole and thiazole derivatives.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; HeLa Cells; Humans; Microbial Sensitivity Tests; Pyrazoles; Structure-Activity Relationship; Thiazoles; Vero Cells; Viruses | 2009 |
Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid.
Topics: Anti-Bacterial Agents; Antiviral Agents; Bacteria; Cells, Cultured; Curcumin; Dipeptides; Fatty Acids; Folic Acid; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure | 2010 |
"Viologen" dendrimers as antiviral agents: the effect of charge number and distance.
Topics: Anti-HIV Agents; Antiviral Agents; Cell Line; Dendrimers; HIV; Humans; Static Electricity; Structure-Activity Relationship; Viologens | 2010 |
Synthesis, antiviral activity and cytotoxicity evaluation of Schiff bases of some 2-phenyl quinazoline-4(3)H-ones.
Topics: Antiviral Agents; Cell Line; Drug Evaluation, Preclinical; Humans; Magnetic Resonance Spectroscopy; Quinazolines; Schiff Bases; Spectrophotometry, Infrared | 2010 |
4-[1-(Substituted aryl/alkyl carbonyl)-benzoimidazol-2-yl]-benzenesulfonic acids: synthesis, antimicrobial activity, QSAR studies, and antiviral evaluation.
Topics: Animals; Anti-Infective Agents; Benzenesulfonates; Cell Survival; Cells, Cultured; Chlorocebus aethiops; Dogs; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Quantitative Structure-Activity Relationship; Stereoisomerism; Structure-Activity Relationship; Vero Cells; Viruses | 2010 |
Synthesis of new C5-(1-substituted-1,2,3-triazol-4 or 5-yl)-2'-deoxyuridines and their antiviral evaluation.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Proliferation; Cells, Cultured; Chlorocebus aethiops; Cyclization; Deoxyuridine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Mice; Microbial Sensitivity Tests; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship; T-Lymphocytes; Vero Cells; Viruses | 2011 |
New prodrugs of Adefovir and Cidofovir.
Topics: Adenine; Animals; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytomegalovirus; Cytosine; Herpesvirus 3, Human; HIV; Humans; Organophosphonates; Prodrugs; Simplexvirus | 2011 |
Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a 1,2,3-triazole linker.
Topics: Animals; Antiviral Agents; Cell Line; Cytostatic Agents; Drug Design; Humans; Inhibitory Concentration 50; Mice; Nucleotides; Triazoles; Viruses | 2012 |
2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies.
Topics: Aminoquinolines; Animals; Antimalarials; Cell Line; DNA; Dogs; Heme; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Plasmodium falciparum; Protoporphyrins; Pyrimidines; Structure-Activity Relationship; Viruses | 2012 |
Synthesis of isoindole and benzoisoindole derivatives of teicoplanin pseudoaglycon with remarkable antibacterial and antiviral activities.
Topics: Anti-Bacterial Agents; Antiviral Agents; Cell Line; Cell Survival; Drug Resistance, Viral; Gram-Positive Bacteria; Herpesvirus 1, Human; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Isoindoles; Microbial Sensitivity Tests; o-Phthalaldehyde; Teicoplanin | 2012 |
Synthesis of 4-aminoquinoline-pyrimidine hybrids as potent antimalarials and their mode of action studies.
Topics: Antimalarials; Antiviral Agents; Cell Line; Chemistry Techniques, Synthetic; DNA; Heme; Humans; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship | 2013 |
Regioselective synthesis of 6-substituted-2-amino-5-bromo-4(3H)-pyrimidinones and evaluation of their antiviral activity.
Topics: Animals; Antiviral Agents; Cells, Cultured; Chlorocebus aethiops; Dogs; Dose-Response Relationship, Drug; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Pyrimidinones; Stereoisomerism; Structure-Activity Relationship; Vero Cells; Viruses | 2013 |
Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues.
Topics: Acrylamides; Adenine; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Survival; Cycloaddition Reaction; Cytomegalovirus; Cytostatic Agents; Drug Design; Enterovirus; Humans; Isoxazoles; Naphthalimides; Nitrogen Oxides; Organophosphonates; Phlebovirus; Simplexvirus; Structure-Activity Relationship; Vaccinia virus | 2015 |
Synthesis and antiviral properties of novel indole-based thiosemicarbazides and 4-thiazolidinones.
Topics: Animals; Antiviral Agents; Cats; Cells, Cultured; Chlorocebus aethiops; DNA Viruses; Dogs; Dose-Response Relationship, Drug; HeLa Cells; Humans; Indoles; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Molecular Structure; RNA Viruses; Semicarbazides; Structure-Activity Relationship; Thiazolidines; Vero Cells; Virus Replication | 2016 |
Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs.
Topics: Antiviral Agents; Cell Line; DNA Viruses; Drug Stability; Humans; Nucleosides; Organophosphonates; Prodrugs; RNA Viruses; Structure-Activity Relationship | 2018 |
Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives.
Topics: Antineoplastic Agents; Antiviral Agents; Apoptosis; Ascorbic Acid; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles; Viruses | 2019 |
Synthesis and biological evaluation of 2-(5-substituted-1-((diethylamino)methyl)-2-oxoindolin-3-ylidene)-
Topics: | 2013 |
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
Topics: Animals; Antiviral Agents; Betacoronavirus; Chlorocebus aethiops; Cloning, Molecular; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Evaluation, Preclinical; Drug Repositioning; HEK293 Cells; Host-Pathogen Interactions; Humans; Immunity, Innate; Mass Spectrometry; Molecular Targeted Therapy; Pandemics; Pneumonia, Viral; Protein Binding; Protein Biosynthesis; Protein Domains; Protein Interaction Mapping; Protein Interaction Maps; Receptors, sigma; SARS-CoV-2; SKP Cullin F-Box Protein Ligases; Vero Cells; Viral Proteins | 2020 |
Phenoxazine nucleoside derivatives with a multiple activity against RNA and DNA viruses.
Topics: Animals; Antiviral Agents; Cell Line, Tumor; Chlorocebus aethiops; DNA Viruses; Dogs; Humans; Madin Darby Canine Kidney Cells; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Oxazines; SARS-CoV-2; Structure-Activity Relationship; Vero Cells; Virus Replication | 2021 |