Page last updated: 2024-08-16

ribavirin and allopurinol

ribavirin has been researched along with allopurinol in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19905 (23.81)18.7374
1990's3 (14.29)18.2507
2000's5 (23.81)29.6817
2010's8 (38.10)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Weber, G2
Leyland-Jones, B; O'Dwyer, PJ; Stewart, JA; Wagner, BH1
Hoffman, R; Jayaram, HN; Lapis, E; Natsumeda, Y; Tricot, GJ; Weber, G; Yamada, Y; Yamaji, Y1
Culham, CA; Hartshorn, JN; Haugh, LD; Krakoff, IR; McCormack, JJ; Newman, RA; Roberts, JD; Stewart, JA; Young, JA1
Allsop, J; Watts, RW1
Chiba, P; Gharehbaghi, K; Lhotka, C; Pillwein, K; Ressmann, G; Schuchter, K; Szalay, SM; Szekeres, T1
Findenig, G; Fritzer, M; Lhotka, C; Schön, HJ; Szekeres, T1
Wang, CH; Xing, XH; Zhang, C1

Reviews

2 review(s) available for ribavirin and allopurinol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Aminothiadiazole: an antineoplastic thiadiazole.
    Cancer treatment reports, 1986, Volume: 70, Issue:7

    Topics: Allopurinol; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Evaluation; Drug Evaluation, Preclinical; Humans; IMP Dehydrogenase; Mice; Neoplasms, Experimental; Purines; Rats; Ribavirin; Thiadiazoles

1986

Trials

1 trial(s) available for ribavirin and allopurinol

ArticleYear
Aminothiadiazole: an antineoplastic thiadiazole.
    Cancer treatment reports, 1986, Volume: 70, Issue:7

    Topics: Allopurinol; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Evaluation; Drug Evaluation, Preclinical; Humans; IMP Dehydrogenase; Mice; Neoplasms, Experimental; Purines; Rats; Ribavirin; Thiadiazoles

1986

Other Studies

19 other study(ies) available for ribavirin and allopurinol

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
IMP dehydrogenase and GTP as targets in human leukemia treatment.
    Advances in experimental medicine and biology, 1991, Volume: 309B

    Topics: Adult; Aged; Allopurinol; Antineoplastic Agents; Female; Genes, myc; Genes, ras; Guanosine Triphosphate; Humans; IMP Dehydrogenase; In Vitro Techniques; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Ribavirin; Tumor Cells, Cultured

1991
Critical issues in chemotherapy with tiazofurin.
    Advances in enzyme regulation, 1989, Volume: 29

    Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Down-Regulation; Drug Interactions; Female; Genes, ras; Guanine; Humans; Hypoxanthine; Hypoxanthines; Leukemia; Liver Neoplasms, Experimental; Male; Middle Aged; Ribavirin; Ribonucleosides; Tretinoin; Tumor Cells, Cultured; Uric Acid

1989
Enzyme-pattern-targeted chemotherapy with tiazofurin and allopurinol in human leukemia.
    Advances in enzyme regulation, 1988, Volume: 27

    Topics: Adenine; Aged; Allopurinol; Animals; Drug Evaluation; Female; Guanine; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Ketone Oxidoreductases; Leukemia; Leukemia, Myeloid, Acute; Liver Neoplasms, Experimental; Male; Middle Aged; Rats; Ribavirin; Ribonucleosides; Tumor Cells, Cultured

1988
Phase I trial of tiazofurin administered by i.v. bolus daily for 5 days, with pharmacokinetic evaluation.
    Cancer treatment reports, 1987, Volume: 71, Issue:2

    Topics: Adult; Aged; Allopurinol; Antimetabolites, Antineoplastic; Creatine Kinase; Drug Administration Schedule; Drug Evaluation; Female; Headache; Hemoglobins; Humans; Hypoxanthines; Isoenzymes; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Nausea; Purines; Ribavirin; Ribonucleosides; Uric Acid; Xanthine; Xanthines

1987
Purine de novo synthesis in liver and developing rat brain, and the effect of some inhibitors of purine nucleotide interconversion.
    Enzyme, 1983, Volume: 30, Issue:3

    Topics: Aging; Alanine; Allopurinol; Animals; Animals, Newborn; Anti-Bacterial Agents; Azaserine; Brain; Female; Fetus; Liver; Male; Pregnancy; Purine Nucleotides; Purines; Rats; Rats, Inbred Strains; Ribavirin; Ribonucleosides

1983
Synergistic action of tiazofurin with hypoxanthine and allopurinol in human neuroectodermal tumor cell lines.
    Biochemical pharmacology, 1993, Dec-03, Volume: 46, Issue:11

    Topics: Allopurinol; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Guanosine Monophosphate; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Neuroblastoma; Ribavirin; Tumor Cells, Cultured

1993
[Synergistic cytotoxic effects of chemotherapy in colon tumor cells by simultaneous inhibition of de novo and salvage energy metabolism pathways].
    Wiener klinische Wochenschrift, 1994, Volume: 106, Issue:14

    Topics: Allopurinol; Antimetabolites, Antineoplastic; Benzamidines; Cell Line; Cell Survival; Colonic Neoplasms; Cytarabine; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Gemcitabine; Humans; Hypoxanthine; Hypoxanthines; Ribavirin; Ribonucleotide Reductases; Tumor Cells, Cultured; Tumor Stem Cell Assay

1994
Xanthine dehydrogenase: An old enzyme with new knowledge and prospects.
    Bioengineered, 2016, Volume: 7, Issue:6

    Topics: 5'-Nucleotidase; Adenosine Deaminase; Aldehydes; Animals; Biodegradation, Environmental; Humans; Nitric Oxide; Oxidation-Reduction; Phosphorus; Pterins; Purines; Reactive Oxygen Species; Ribavirin; Xanthine Dehydrogenase; Xanthine Oxidase

2016