Page last updated: 2024-08-16

ribavirin and adenosine kinase

ribavirin has been researched along with adenosine kinase in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's1 (10.00)18.2507
2000's2 (20.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carson, DA; Seegmiller, JE; Willis, RC1
Alvarez, E; Robins, RK; Saunders, PP; Spindler, CD; Tan, MT1
Connelly, MC; Fridland, A; Robbins, TJ1
Matthews, TR; Smee, DF1
Robins, RK; Seegmiller, JE; Willis, RC1
Eyring, H; Miles, DL; Miles, DW1
Hong, Z; Larson, G; Shim, JH; Walker, H; Wu, JZ1
Arterburn, JB; Chung, K; Jeselnik, M; Jonsson, CB; Kumarapperuma, SC; Parker, WB; Sun, Y1
Ariumi, Y; Hiramoto, A; Hiraoka, O; Ikeda, M; Kato, N; Mori, K; Wataya, Y1
Baumert, TF; Felmlee, DJ; Xiao, F1

Other Studies

10 other study(ies) available for ribavirin and adenosine kinase

ArticleYear
Adenosine kinase initiates the major route of ribavirin activation in a cultured human cell line.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:7

    Topics: Adenosine Kinase; Cell Line; Formates; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; IMP Dehydrogenase; Inosine; Inosine Monophosphate; Lymphocytes; Phosphates; Phosphotransferases; Ribavirin; Ribonucleosides

1978
Tiazofurin is phosphorylated by three enzymes from Chinese hamster ovary cells.
    Cancer research, 1990, Sep-01, Volume: 50, Issue:17

    Topics: Adenosine Kinase; Adenosine Triphosphate; Animals; Antimetabolites, Antineoplastic; Biotransformation; Cell Line; Cricetinae; Cricetulus; Female; Inosine Monophosphate; Kinetics; Niacinamide; Ovary; Phosphorylation; Pyridinium Compounds; Ribavirin; Ribonucleosides

1990
Tiazofurin metabolism in human lymphoblastoid cells: evidence for phosphorylation by adenosine kinase and 5'-nucleotidase.
    Cancer research, 1986, Volume: 46, Issue:2

    Topics: 5'-Nucleotidase; Adenosine Kinase; Adenosine Triphosphate; Amides; Biotransformation; Cell Line; Drug Resistance; Humans; Inosine Monophosphate; Lymphocytes; Nucleotidases; Phosphorylation; Phosphotransferases; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Substrate Specificity

1986
Metabolism of ribavirin in respiratory syncytial virus-infected and uninfected cells.
    Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:1

    Topics: Adenosine Kinase; Animals; Biotransformation; Cells, Cultured; Chlorocebus aethiops; Nucleotides; Phosphorylation; Respiratory Syncytial Viruses; Respirovirus Infections; Ribavirin; Ribonucleosides

1986
An in vivo and in vitro evaluation of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine: an inhibitor of human lymphoblast purine nucleoside phosphorylase.
    Molecular pharmacology, 1980, Volume: 18, Issue:2

    Topics: Adenosine Kinase; Cell Line; Formycins; Humans; Hypoxanthine Phosphoribosyltransferase; IMP Dehydrogenase; Inosine; Lymphocytes; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Ribavirin; Ribonucleosides

1980
Implications of a circular dichroism and theoretical investigation of ribavirin-related derivatives in drug design.
    Annals of the New York Academy of Sciences, 1981, Volume: 367

    Topics: Adenosine Kinase; Chemistry, Pharmaceutical; Circular Dichroism; DNA-Directed RNA Polymerases; IMP Dehydrogenase; Molecular Conformation; Quantum Theory; Ribavirin; Ribonucleosides; Structure-Activity Relationship; Thermodynamics

1981
Phosphorylation of ribavirin and viramidine by adenosine kinase and cytosolic 5'-nucleotidase II: Implications for ribavirin metabolism in erythrocytes.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:6

    Topics: 5'-Nucleotidase; Adenosine Kinase; Animals; Antiviral Agents; Cricetinae; Cytosol; Erythrocytes; Humans; Kinetics; Phosphorylation; Ribavirin

2005
Structural effects on the phosphorylation of 3-substituted 1-beta-D-ribofuranosyl-1,2,4-triazoles by human adenosine kinase.
    Bioorganic & medicinal chemistry letters, 2007, Jun-01, Volume: 17, Issue:11

    Topics: Adenosine Kinase; Antiviral Agents; Computers; Humans; Models, Molecular; Molecular Structure; Phosphorylation; Ribavirin; Stereoisomerism; Triazoles

2007
Adenosine kinase is a key determinant for the anti-HCV activity of ribavirin.
    Hepatology (Baltimore, Md.), 2013, Volume: 58, Issue:4

    Topics: Adenosine Kinase; Antiviral Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resistance, Viral; Hepacivirus; Hepatitis C; Hepatocytes; Humans; Liver Neoplasms; Phenotype; Ribavirin; RNA, Viral; Treatment Outcome

2013
Modeling the antiviral activity of ribavirin against hepatitis C virus in cell culture.
    Hepatology (Baltimore, Md.), 2013, Volume: 58, Issue:4

    Topics: Adenosine Kinase; Antiviral Agents; Hepacivirus; Hepatitis C; Hepatocytes; Humans; Ribavirin

2013