rhodioloside has been researched along with glucose, (beta-d)-isomer in 554 studies
| Studies (rhodioloside) | Trials (rhodioloside) | Recent Studies (post-2010) (rhodioloside) | Studies (glucose, (beta-d)-isomer) | Trials (glucose, (beta-d)-isomer) | Recent Studies (post-2010) (glucose, (beta-d)-isomer) |
|---|---|---|---|---|---|
| 621 | 2 | 519 | 21,956 | 883 | 10,747 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (1.26) | 18.2507 |
| 2000's | 67 (12.09) | 29.6817 |
| 2010's | 340 (61.37) | 24.3611 |
| 2020's | 140 (25.27) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, J; Chu, K; Hong, G; Huang, X; Lai, W; Liu, J; Tang, Y; Wang, Y; Yang, Z | 1 |
| Wang, FP; Wang, S; You, XT | 1 |
| Kang, S; Lu, D; Lu, Y; Zhang, J | 1 |
| Chai, FL; Chen, QM; Hai, P; Jin, KP; Ye, YC; Zhou, SX | 1 |
| Ge, YC; Li, XH; Peng, JN | 1 |
| Hong, SP; Jian, JJ; Kang, JS; Kim, YH; Linh, PT | 1 |
| Cui, J; Li, J; Wang, B; Zhao, Y | 1 |
| Darbinyan, V; Gabrielian, E; Kteyan, A; Panossian, A; Wagner, H; Wikman, G | 1 |
| An, F; Guo, D; Yue, S; Zheng, J | 1 |
| Abad Martínez, MJ; Bermejo Benito, P; Díaz Lanza, AM; Fernández Matellano, L; Recuero Carretero, C; Silván Sen, AM; Villaescusa Castillo, L | 1 |
| Kang, S; Liu, F; Wang, J; Xu, Z; Zhang, J | 1 |
| Chen, F; Li, HB | 1 |
| Cao, X; Han, X; Ito, Y; Wei, Y; Zhang, T | 1 |
| Aphalo, PJ; Julkunen-Tiitto, R; Tegelberg, R | 1 |
| Hori, M; Inoue, K; Kuwajima, H; Yamamoto, H | 1 |
| Cho, H; Kim, JH; Kim, JS; Kim, YC; Ko, GI; Nan, JX; Oh, H; Sohn, DH; Song, EK | 1 |
| Chen, X; Cui, S; Hu, X; Hu, Z | 1 |
| Hohtola, A; Jalonen, J; Tolonen, A | 1 |
| Wu, M; Wu, S; Zu, Y | 1 |
| Bianco, A; Melchioni, C; Ramunno, A; Romeo, G; Uccella, N | 1 |
| Guo, S; Shang, X; Wang, Y; Yan, X | 1 |
| Briedis, V; Kucinskaite, A; Savickas, A | 1 |
| Chen, WH; Wang, SH; Wang, WJ; Wang, XF | 1 |
| Deng, RC; Ma, CX; Niu, FL; Zhang, WS; Zhu, LQ | 1 |
| Bi, H; Hu, TQ; Jiang, Y; Sheng, CZ; Yuan, YJ | 1 |
| Cao, LL; Du, GH; Wang, MW | 1 |
| Chen, YF; Hung, XQ; Zhang, XS; Zhu, BD | 1 |
| Liu, Y; Zhang, Y | 1 |
| Han, F; Li, SM; Meng, J; Wang, SF | 1 |
| Bai, H; Chang, X; Dou, D; Kang, T; Koike, K; Li, J; Li, W; Ma, G; Nikaido, T; Satou, T; Sun, D | 1 |
| Chen, DS; Chen, J; Di, DL; Jiang, SX; Li, C | 1 |
| Chen, Z; Jin, S; Yan, S; Zhang, X; Zhu, B | 1 |
| Mattioli, L; Perfumi, M | 1 |
| Li, T; Sun, C; Wu, L; Xu, G | 1 |
| Liu, B; Wang, X; Wu, Y; Xu, H; Zhou, X | 1 |
| Gao, DY; Li, YF; Li, ZQ; Liu, BY; Lü, SY; Ma, LQ; Pang, XB; Wang, H; Yan, F; Ye, HC; Yu, HS | 1 |
| Cao, G; Chen, B; Lin, X; Sun, Y; Tan, C; Wang, Z; Yu, H; Zhang, L | 1 |
| Chen, L; Hu, C; Meehan, EJ; Yu, P | 1 |
| Fan, M; Xia, S; Xu, S; Zhang, X | 1 |
| Chen, L; Li, Z; Xu, X; Zuo, G | 1 |
| Li, Y; Mao, Y; Yao, N | 1 |
| Chang, YW; Hsieh, SH; Lu, TJ; Yao, HT; Yeh, TK | 1 |
| Briedis, V; Krauze-Baranowska, M; Kucinskaite, A; Pobłocka-Olech, L; Savickas, A; Sznitowska, M | 1 |
| Lu, G; Mao, Y; Zhang, X | 1 |
| Abrahamyan, H; Gabrielyan, E; Hovhannisyan, A; Nikoyan, N; Ohanyan, N; Panossian, A; Wikman, G | 1 |
| He, Y; Liang, Y; Liu, L; Liu, X; Liu, Y; Wang, D; Wang, G; Wei, W; Wen, T; Xie, L; Yu, S | 1 |
| Lin, GQ; Lu, WY; Xu, JH; Yu, HL | 1 |
| Gao, DY; Hu, TS; Li, GF; Li, YF; Lü, SY; Ma, LQ; Pang, XB; Wang, H; Wang, HH; Wang, YN; Ye, HC; Zhang, JX | 1 |
| Ding, F; Gu, X; Liu, M; Yu, S | 1 |
| Ge, YK; Li, HB; Zhang, L; Zheng, XX | 1 |
| Han, XH; Nan, JX; Piao, DM; Wu, YL | 1 |
| Chen, X; Ding, F; Gu, X; Liu, J | 1 |
| Furmanowa, M; Malinowski, M; Mazurkiewicz, M; Siwicki, AK; Skopińska-Rózewska, E; Sommer, E; Wasiutyński, A | 1 |
| Lin, GQ; Lu, WY; Su, JH; Xu, JH; Yu, HL | 1 |
| Li, MH; Wang, YS; Zhang, GZ | 1 |
| Cai, L; Li, Q; Qian, Y; Wang, H; Yao, W | 1 |
| Ding, Y; Sun, X; Wang, H; Wang, S; Zhou, J | 1 |
| Ma, ZJ; Zhao, ZJ | 1 |
| Gu, X; Hu, L; Ma, C; Tang, J; Tao, G; Wang, H | 1 |
| Chen, L; Chen, X; Du, S; Lu, Q; Luo, J; Peng, Y; Xie, Y; Yang, W | 1 |
| Choi, BM; Chung, HT; Jang, SI; Jeong, S; Kang, KJ; Kim, HY; Kim, YC; Lee, HJ; Oh, GS; Pae, HO; Yun, YG | 1 |
| Cai, ZY; Deng, XM; Li, JB; Mao, YF; Zou, YQ | 1 |
| Cai, DL; Li, HX; Ma, L; Pei, SP; Tong, BD; Wang, Y | 1 |
| Chen, J; Hou, R; Jia, X; Jiang, W; Liu, A; Zhang, J | 1 |
| Bi, S; Jin, Z; Liu, W; Wu, T; Yang, X; Yi, D; Zhou, H | 1 |
| Li, HX; Ng, TB; Sze, SC; Tong, Y | 1 |
| Ao, H; Gao, XF; Shi, HM; Sun, T | 1 |
| Chen, S; Gao, X; Hu, R; Yao, W; Yin, D | 1 |
| Hu, LP; Li, J; Lu, B; Shao, JQ; Sun, LJ; Wang, GH; Wang, J; Wang, Q; Wang, YT; Wu, B | 1 |
| György, Z; Hohtola, A; Jaakola, L; Neubauer, P | 1 |
| Chen, X; Cheng, Q; Ding, F; Zhang, Q | 1 |
| Abrahamyan, A; Avanessian, A; Bussel, I; Gazarian, M; Holmbeck, MA; Jafari, M; Maler, S; Schriner, SE | 1 |
| Du, GH; Gao, M; Tan, CB; Xu, WR; Yang, XY; Zhu, XM | 1 |
| Grace, MH; Kurmukov, AG; Lila, MA; Raskin, I; Yousef, GG | 1 |
| Ding, F; Liu, J; Shen, Y; Yu, S | 1 |
| Jiang, YZ; Lian, LH; Nan, JX; Wu, YL | 1 |
| Ma, X; Wan, X; Zhang, T; Zheng, Y; Zhu, J; Zhu, Y | 1 |
| Hu, X; Lin, S; Mei, R; Qiu, S; Yu, D; Zhang, X | 1 |
| Fan, JM; Li, FY; Liu, C; Xie, XS; Zhang, HP; Zhang, L | 1 |
| Jäger, AK; Kudsk, DS; Mølgaard, P; Saaby, L; Witt, KC | 1 |
| Deng, HB; Li, DD; Li, YY; Mao, GX; Wang, Z; Yuan, LG | 1 |
| Hu, X; Lin, S; Qiu, S; Yu, D; Zhang, X | 1 |
| Chen, SD; Ding, JQ; Li, QY; Ma, JF; Wang, HM; Wang, ZQ | 1 |
| Hong, DS; Lou, J; Ouyang, JF; Qiao, HX; Ren, ZH; Yan, C | 1 |
| Cao, G; Lin, X; Tan, C; Wang, Z; Yu, H; Zhang, L; Zhao, X | 1 |
| Chen, Y; Gao, Z; Hong, D; Ouyang, J; Qiao, H; Ren, Z | 1 |
| Ciccocioppo, R; Cifani, C; Massi, M; Micioni Di Bonaventura, MV; Ruggieri, V; Vitale, G | 1 |
| Ge, DT; Kong, SK; Qian, EW | 2 |
| Guo, Y; Meng, Y; Yang, Y; Zhao, Y; Zheng, C | 1 |
| Wu, LX; Xin, H; Zhong, H; Zhu, YZ | 1 |
| He, CH; Hu, JP; Rena, K; Wang, XL; Wang, XM; Wang, XQ | 1 |
| Chen, J; Kang, X; Li, X; Liang, Q; Sun, X; Tao, L; Ye, X | 1 |
| Chung, YS; Hu, GS; Hur, YJ; Jia, JM; Kim, DH; Lee, JH; Park, SK; Yi, YB; Yun, DJ | 1 |
| Chen, B; Chen, G; Zhang, L | 1 |
| Chao, PC; Chin, LW; Chou, MC; Chou, MY; Lai, YY; Lin, LY; Lin, SS; Wei, JC; Yang, CC | 1 |
| Ye, SS; Yin, LL; Zeng, YY | 1 |
| Chen, A; Gorecki, D; Hou, F; Jin, P; Lu, S; Luo, M; Ma, J; Ma, YC; Patel, AV; Wang, XQ; Xu, I | 1 |
| Hu, YH; Ma, LQ; Shi, GL; Wang, YN; Yu, HS; Zhang, JX | 1 |
| Chen, X; Ding, F; Liu, J; Yang, Y; Zhang, S; Zhou, X | 1 |
| Deng, X; Guan, S; Huang, G; Lu, J; Qian, W; Wang, W; Wang, X | 1 |
| Guo, YH; Kang, CY; Li, T; Li, TZ; Liu, CT; Wang, Y; Yuan, M; Zou, L | 1 |
| Jafari, M; Li, X; Liu, Z; Simoneau, AR; Zi, X | 1 |
| Ma, LQ; Qin, YF; Shi, GL; Wang, HT; Wang, YN; Yu, HS; Zhang, H; Zhang, JX | 1 |
| Fan, K; Hao, SH; Huang, S; Wang, JQ; Wang, P; Zhang, XL | 1 |
| Chen, HL; Huang, DJ; Ji, YJ; Jiang, W; Shi, YP; Wang, X; Wu, D; Wu, SS; Zhu, Y | 1 |
| Chen, A; Gorecki, D; Hou, FF; Jin, P; Lu, S; Luo, M; Ma, J; Ma, YC; Patel, AV; Terevsky, N; Wang, XQ; Xu, I | 1 |
| Deng, X; Guan, S; Guo, W; He, J; Lu, J; Wei, J | 1 |
| Bayliak, MM; Lushchak, VI | 1 |
| Guo, Y; Li, X; Si, Y; Yang, Y; Zhao, Y; Zhu, H | 1 |
| Sun, C; Wang, Z; Zhang, H; Zheng, Q | 1 |
| Chen, N; Deng, X; Feng, H; Guan, S; Guo, W; Huang, G; Huo, M; Lu, J; Song, B; Xiong, Y; Zhong, W | 1 |
| Chen, J; Li, CD; Wang, CQ; Wu, B | 1 |
| Circosta, C; Occhiuto, F; Palumbo, DR; Spadaro, F | 1 |
| Feng, SF; Li, XQ; Liu, SB; Shi, TY; Tian, Z; Wu, YM; Xing, JH; Zhang, N; Zhao, MG | 1 |
| Gong, J; Li, F; Meng, X; Peng, Y; Tang, H; Xiao, F | 1 |
| Chan, WY; Li, Y; Lin, YK; Qu, ZQ; Zeng, YS; Zhong, ZQ; Zhou, Y | 1 |
| Brackman, G; Coenye, T; De Witte, E; Honraet, K; Nelis, HJ; Rigole, P; Rossel, B | 1 |
| Bi, CW; Choi, RC; Dong, TT; Guo, AJ; Lau, DT; Tsim, KW; Xu, SL; Zhan, JY; Zhang, ZX; Zheng, KY; Zhu, KY | 1 |
| Lu, L; Yuan, J; Zhang, S | 1 |
| Dong, J; Ge, B; Li, Z; Wen, Y; Yang, Y; Zhang, M; Zhang, Q; Zhao, H | 1 |
| Du, W; Li, X; Pang, Q; Sipple, J | 1 |
| Li, MH; Ouyang, JQ; Tang, CF | 1 |
| Chen, J; Wang, CQ | 1 |
| Fan, X; Guo, N; Hu, Z; Li, H; Wang, Y; Xu, T; Yu, T; Zhang, D; Zheng, J | 1 |
| Chen, J; Ding, W; Huang, J; Li, X; Sun, H; Xie, Y; Zhang, L; Zhou, Q | 1 |
| Gao, D; Li, Y; Liu, C; Ma, L; Wang, Y; Yu, H; Zhang, J | 1 |
| Deng, LC; Gao, CH; Shen, D; Shen, WS; Zhang, H | 1 |
| Isaak, CK; Liu, Y; O, K; Petkau, JC; Siow, YL; Sun, L; Zhou, Y | 1 |
| Chen, N; Chu, X; Deng, X; Guan, S; Huo, M; Lu, J; Song, B; Song, Y; Wang, D; Xiong, Y | 1 |
| Chen, Q; Wang, F; Yang, L; Zhang, G | 1 |
| Cao, Y; Fu, Y; Guo, M; Li, D; Li, F; Liang, D; Liu, B; Liu, Z; Su, G; Yang, Z; Zhang, N; Zhang, W; Zhang, X | 1 |
| Li, Y; Xu, J | 1 |
| Gao, LL; Li, X; Peng, HY; Xing, Y; Yang, XE; Zhang, MX | 1 |
| Chen, CC; Chen, SF; Hung, TH; Lee, CY; Liao, NC; Tsai, HJ; Wang, PY; Wu, CH | 1 |
| Ding, ZH; Guo, L; Jiang, LH; Liu, WL; Lv, C; Ou, CS; Zheng, L; Zhou, MJ | 1 |
| Chai, X; Kong, W; Liu, P; Shao, T; Song, L; Wen, X; Zhang, J | 1 |
| Karkour, C; Peschel, W; Prieto, JM; Williamson, EM | 1 |
| Xie, H; Zhu, DH | 1 |
| Han, T | 1 |
| Sheng, QS; Wang, ZJ; Zhang, J; Zhang, YG | 1 |
| Chen, BF; Yang, YF; Zhang, YT | 1 |
| Bai, C; Chen, L; Dong, R; Li, J; Luo, M; Peng, H; Wang, S; Xiong, H; Zhang, Z; Zhao, Q | 1 |
| Chai, XQ; Kong, WN; Li, X; Shao, TM; Song, LG; Zhang, J; Zhen, YF | 1 |
| Gao, XF; Shi, HM; Wang, H; Xu, MC | 2 |
| Chen, JZ; Fan, J; Hu, HM; Li, D; Liu, J; Luo, ZJ; Meng, GL; Shi, TY; Wei, BY; Yang, L; Yuan, Z; Zhang, JK | 1 |
| Ding, Z; Guo, Y; Ling, Y; Liu, Q; Wu, B; Yang, Y; Yuan, Y; Zhao, J; Zhao, Y | 1 |
| Liu, X; Wu, SJ; Yuan, Y; Zhang, LL | 1 |
| Hwang, YH; Ma, JY; Park, H | 1 |
| Bian, K; Liu, D; Nie, XQ; Pan, HJ | 1 |
| Bello, NT; Verpeut, JL; Walters, AL | 1 |
| Chen, L; Gao, JQ; Liang, WQ; Liu, S; Peng, LH; Shan, YH; Wei, W; Xu, SY | 1 |
| Kolosov, VP; Li, Q; Perelman, JM; Zhou, XD | 1 |
| Chen, X; Jiao, Q; Liu, Y; Lu, HX; Qi, C; Yang, P; Zhang, J; Zhang, P | 1 |
| Luo, XP; Ning, Q; Qi, JY; Wang, HW; Wang, YQ; Wu, T | 1 |
| Ishida, T | 1 |
| Jin, L; Luo, Z; Shen, N; Xu, B; Zhang, W; Zhao, X; Zhu, H | 1 |
| Chen, G; Chen, ST; Huang, XJ; Lü, BD; Yang, KB; Zhang, SG | 1 |
| Li, L; Lin, L; Liu, J; Xiang, F; Xu, D; Zhang, Y; Zhang, Z | 1 |
| Chen, JJ; Deng, HB; He, XB; Li, DD; Li, ZR; Mao, GX; Qiu, Q; Si, SY; Song, DQ; Wang, Z; Zhan, YC; Zhang, NF | 1 |
| Chen, HL; Chen, JX; Guo, ZY; Jiang, W; Li, P; Li, RL; Wang, X; Wang, XL; Wang, XX; Xiong, LL; Zhu, Y | 1 |
| Chang, K; Chen, M; Huang, W; Lan, X; Liao, Z; Liu, W; Liu, X; Qiu, F; Quan, H; Wang, Q; Zeng, L; Zheng, W | 1 |
| Guan, S; Huang, G; Li, G; Liu, J; Lu, J; Song, B; Wang, Z; Xiong, Y; Xu, L | 1 |
| Bai, J; Chen, YN; Liu, H; Liu, Y; Wang, Y; Zhao, HB; Zhu, XJ | 1 |
| Hu, Y; Huang, Y; Liu, C; Liu, J; Lu, Y; Tao, Y; Wang, D; Wu, Y; Yu, Y; Zhao, X | 1 |
| Ling, Y; Xu, W; Yang, X; Yang, Y; Zhao, W; Zhao, Y | 1 |
| Mattioli, L; Perfumi, M; Titomanlio, F | 1 |
| Du, W; Erden, O; Li, L; Li, X; Wilson, A; Ye, Q | 1 |
| Dong, JZ; Ha, XQ; Li, XY; Ma, H; Yang, YS; Zhang, M; Zhao, HB; Zheng, P | 1 |
| Bai, H; Bao, S; Liu, L; Sun, YQ; Wei, YP; Xi, R | 1 |
| Li, W; Luo, M; Ning, F; Peng, H; Xiong, H; Yao, L; Zhao, Q; Zhu, X | 1 |
| Jiang, Y; Sun, J; Tu, PF; Xia, F | 1 |
| Cao, X; Liu, H; Wang, Y; Xu, P; Zhou, Y | 1 |
| Jacobi, A; Liebers, C; Stiehler, M; Tang, Y; Vater, C; Zou, X | 1 |
| Ding, W; Guo, N; Hu, Z; Wang, Y; Wang, Z | 1 |
| Peng, YS; Wang, RF; Wu, XW | 1 |
| Chen, Y; Fan, CM; Fang, DL; He, LL; He, ZY; Lei, Y; Ren, K; Song, XR; Xu, B | 1 |
| Jin, HG; Kim, AR; Ko, HJ; Lee, SK; Woo, ER | 1 |
| Huang, J; Sun, C; Wang, M; Wu, B; Xian, H; Yang, Y; Zhao, J; Zheng, Y | 1 |
| Gao, JQ; Liang, WQ; Liu, S; Peng, LH; Shan, YH; Wei, W; Wu, JH; Xu, SY; Zhang, CZ | 1 |
| Bo, L; Deng, X; Hu, B; Li, J; Liu, S; Wang, J; Zhu, J; Zou, Y | 1 |
| Cheng, SM; Huang, CY; Lai, MC; Lai, MH; Lee, SD; Lin, JG; Lin, YM; Liu, YF; Pai, PY; Yeh, YL | 1 |
| Chen, C; Deng, W; Huang, C; Tang, Y; Wu, T | 1 |
| Bian, F; Chi, J; Jin, S; Li, W; Wu, D; Xing, S; Xu, G; Yang, X; Zhang, Y | 1 |
| Chen, G; Fu, HY; Huang, XJ; Lü, BD; Yang, F; Zhao, JF | 1 |
| Chen, J; Chen, L; He, H; Wang, S; Zhang, W; Zhang, X | 1 |
| Deng, J; Hu, M; Huang, A; Huang, Z; Li, H; Liang, M; Ma, F; Xiao, L; Yang, F; Zhang, J | 1 |
| Chen, Z; Wu, X | 1 |
| Bai, J; Dong, JZ; Ha, XQ; Li, XY; Qi, SN; Yang, YS; Zhang, QW; Zhao, HB; Zhao, L | 1 |
| Li, HF; Zhang, XL | 1 |
| Chen, L; Li, Z; Lin, R; Mao, J; Zhong, X | 1 |
| Li, C; Li, YR; Wang, ZM; Yang, LX | 1 |
| Hu, M; Wang, J; Wang, Q; Xiao, L; Yan, T; Zhu, L | 1 |
| Jin, RG; Wang, J; Wang, QJ; Xiao, L; Yan, TH | 1 |
| Li, Y; Lu, H; Sheng, Z; Zheng, K | 1 |
| Fu, Q; Kang, DY; Ma, SP; Ma, ZQ; Qu, R; Yang, SJ; Yu, HY | 1 |
| Guo, N; Han, X; Sui, D; Wang, Y; Yang, Q; Zhu, M | 1 |
| Bai, H; Ma, XH; Wang, CB; Wei, YP; Xi, R; Zhang, Q; Zhao, Q | 1 |
| Guan, F; Jin, LH; Wang, C; Zhu, C | 1 |
| Efferth, T; Hamm, R; Panossian, A; Wikman, G | 1 |
| Bai, Y; Bi, H; Cai, T; Liu, C; Liu, T; Liu, X; Ma, Y; Zhang, X; Zhuang, Y | 1 |
| Choi, YH; Yan, GH | 1 |
| Chen, X; Guo, W; Li, J; Liu, C; Shi, X; Zhao, W | 1 |
| Feng, N; Guo, T; Lu, M; Wu, Z; Ye, B; Zhang, K; Zhang, Y; Zhao, J; Zhu, C | 1 |
| Jin, H; Liu, D; Lu, Y; Pei, L; Shu, X; Tian, Q; Wang, L; Wang, S; Wei, N; Wu, Y; Yan, H; Yan, T; Yang, X; Yao, C | 1 |
| Bian, J; Gu, J; Han, T; Hu, D; Liu, X; Liu, Z; Wang, Y; Xie, J; Yuan, Y; Zhao, H; Zou, H | 1 |
| Hu, L; Lv, W; Ma, C; Tao, G; Wang, H | 1 |
| Jia, BB; Jin, XQ; Mao, GX; Wang, GF; Wang, YZ; Wen, XL; Xing, WM; Yan, J; Yang, ZX | 1 |
| Ding, L; Huang, X; Wu, L; Xu, L; Zhang, Z; Zheng, L | 1 |
| Bo, L; Deng, X; Hu, B; Li, J; Liu, S; Yu, X; Zou, Y | 1 |
| Chang, X; Gao, J; He, H; Wei, T; Wen, Z; Yan, T; Zhu, L | 1 |
| Bai, X; Bian, F; Chen, X; Chi, J; Jin, S; Li, W; Wu, D; Wu, G; Xing, S; Yang, X; Zhang, Y; Zheng, T | 1 |
| Sun, KX; Xia, HW; Xia, RL | 1 |
| Cui, JL; Guo, TT; Ren, ZX; Wang, ML; Zhang, NS | 1 |
| Cai, H; Cai, X; Chen, M; Chen, Y; Ding, C; Guo, R; Huang, X; Wang, L; Xu, X; Yao, D; Yu, X; Zou, L | 1 |
| Jin, C; Li, Y; Lian, ML; Piao, XC; Shao, CH | 1 |
| Du, Y; Fan, Z; Shi, A; Zhao, G | 1 |
| Chen, J; Hou, XH; Huang, JG; Xing, GX; Yan, ZQ; Zhang, Y | 1 |
| Gao, YW; Tang, L; Wang, ZC; Wei, RB; Xing, Y; Yang, Y; Zheng, XY | 1 |
| Alameddine, A; Ayer, A; Bourreau, J; Custaud, MA; Derbre, S; Fajloun, Z; Gauguier, D; Gauquelin-Koch, G; Navasiolava, N; Yuan, M | 1 |
| Zhang, M; Zheng, G; Zheng, Y; Zhu, F | 1 |
| Brown, J; Chen, L; Chu, K; Hong, G; Lai, W; Wei, Y; Zhang, X; Zheng, Z | 1 |
| Cao, G; Shi, K; Su, Z; Wang, X; Zhang, K; Zhu, J | 1 |
| Chang, TC; Chou, YC; Lai, FY; Lee, SY; Shi, LS; Yen, IC | 1 |
| Guo, C; Liu, R; Qin, GH; Zhao, HB | 1 |
| Colitti, M; Pomari, E; Stefanon, B | 1 |
| Gao, XF; Ge, ZR; Lu, JD; Ruan, C; Shi, HM; Wang, L; Xu, MC; Zhang, JJ; Zhang, Y | 1 |
| Bian, J; Gu, J; Han, T; Hu, D; Liu, X; Liu, ZP; Wang, Y; Yuan, Y; Zhu, J; Zou, H | 1 |
| Chang, X; Gao, J; He, H; Miao, M; Yan, T; Zhu, L | 1 |
| Cao, XB; Chang, YM; Cui, YJ; Jiang, CW; Liu, HY; Meng, ZZ; Ping, Z; Wang, DY; Xu, P; Zhang, LF | 1 |
| Barhwal, K; Das, SK; Hota, SK; Kumar, A; Srivastava, RB | 1 |
| Bai, XL; Bian, F; Chi, JY; Jin, S; Li, WJ; Li, YS; Wu, D; Wu, GJ; Xing, SS; Yang, XY; Zhang, CT; Zhang, YH; Zhang, YZ; Zheng, T | 1 |
| Chang, X; Gao, J; He, H; Jiang, W; Luo, F; Ma, C; Yan, T; Zhou, R; Zhu, L | 1 |
| Chang, X; Gao, J; Gong, S; He, H; Jiang, W; Luo, F; Wei, T; Yan, T; Zhu, L | 1 |
| Li, SP; Luo, X; Wang, XJ; Wang, ZZ; Xiao, W; Zhang, Q; Zhao, YW | 1 |
| Chang, X; Gao, J; He, H; Miao, M; Wei, T; Yan, T; Zhu, L | 1 |
| Cai, Z; Huang, W; Jiang, Y; Li, M; Lou, T; Lu, B; Mao, S; Zhao, Y; Zhou, F | 1 |
| Chang, X; Gao, J; He, H; Liu, Y; Luo, F; Ma, C; Wei, T; Yan, T; Zhou, R; Zhu, L | 1 |
| Dong, X; Li, B; Li, D; Luo, W; Meng, S; Wang, J; Zhang, W; Zhang, X | 1 |
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| Huang, R; Wang, Y; Wang, Z; Xiao, W; Xiao, Y; Yan, J; Yang, R; Zhang, X; Zheng, C; Zhou, J; Zhu, J | 1 |
| Dai, XT; Ding, XJ; Han, JX; Jin, J; Liu, HJ; Sun, T; Wang, HQ; Wang, Y; Yang, K; Yang, YY; Yao, C; Zhang, ZY; Zhu, CB | 1 |
| Jun, L; Ke, Z; Li-Bo, C; Peng-Fei, T; Qing-Qing, S; Ting, L; Xing-Cheng, G; Yue-Lin, S | 1 |
| Hai-Nan, WU; Xiao-Qiang, B | 1 |
| Chun-Hua, MA; Guang-Bo, GE; Qing-Guang, Z; Shou-Ning, J; Shuang-Xi, W; Wen-Juan, C; Xin, LI; Xuan, D | 1 |
| Wang, J; Wang, W; Wang, X; Yang, L; Zhou, L | 1 |
| Jiang, L; Lv, S; Su, J; Wei, J; Xu, X; Zhang, Z; Zheng, L | 1 |
| Cao, Y; Dong, P; Jia, L; Jiang, M; Li, C; Liang, Q; Shi, H; Song, T; Wang, P | 1 |
| Chen, Q; Chen, W; Dong, C; Dong, W; Gong, T; Han, P; Liu, W; Liu, X; Sun, S; Wen, S; Zhao, S | 1 |
| Guo, R; Li, Y; Ni, J; Xu, Y | 1 |
| Buabeid, M; Dhanasekaran, M; Dwyer, D; Fabbrini, M; Fujihashi, A; Govindarajulu, M; Lynd, T; Mohanakumar, KP; Moore, T; Neel, L; Ramesh, S; Shah, K; Smith, F | 1 |
| Li, X; Liu, K; Long, J; Xie, L; Xie, Q; Zhang, X; Zheng, Y | 1 |
| Bian, F; Chen, L; Hao, X; Lei, P; Lu, W; Ma, W; Wang, Q; Zhang, L; Zhang, Y; Zhao, Y; Zheng, T | 1 |
| Fu, H; Huang, W; Lv, B; Ma, J; Ma, K; Wang, W; Xu, Z; Ye, M; Zhao, F; Zhao, J; Zhou, K | 1 |
| AlRamlawy, AM; Alshehri, AS; El-Kenawy, AE; El-Kott, AF; ElBealy, ER; Khalifa, HS | 1 |
| Al-Otaibi, NA; Doherty, MK; Matarèse, BFE; Rahmoune, H; Slater, NKH; Straka, MF; Whitfield, PD | 1 |
| Chen, R; Fan, G; Wu, XY; Yi, H; Zhao, CC | 1 |
| Geng, H; Lei, M; Sun, F; You, L; Zhang, D | 1 |
| Jin, S; Li, Y; Liu, SL; Wei, X; Yang, XY; Zhao, Y | 1 |
| Li, J; Li, L; Li, XR; Ma, Y; Wu, Y; Xu, PX; Xue, M; Zhou, XL | 1 |
| Chen, J; Chen, JH; Hang, WJ; He, BH; Hu, CY; Wen, B; Xu, K; Zhang, QY | 1 |
| Dong, N; Li, S; Qiu, Q; Shi, X; Zhang, J | 1 |
| Chen, FL; Li, XH; Shen, HL | 1 |
| Hu, M; Huang, X; Qi, Z; Shi, H; Wang, X; Wu, Y; Xu, H; Zhang, D; Zhang, Y | 1 |
| Ping, J; Xu, LM; Ye, QN; Zhao, CQ | 1 |
| Feng, L; Li, W; Li, Y; Song, D; Wang, P; Zhao, M | 1 |
| Han, X; Huang, Y; Long, X; Tang, J; Wang, X | 1 |
| Cong, Y; Guo, Y; Li, Y; Liu, Y; Liu, Z; Ren, Y; Wang, T; Wu, X; Zhu, L | 1 |
| Yang, H; Yang, Q; Zheng, L | 1 |
| Liu, C; Qian, J; Wang, X; Weng, W; Zhou, G; Zhu, S | 1 |
| Nan, B; Wang, M; Wang, Z; Xi, C; Yan, H; Yang, C; Ye, H; Yuan, Y; Zhang, Y | 1 |
| Chen, L; Lei, P; Li, X; Lu, W; Ma, W; Wang, Q; Wang, Z; Yan, S; Yu, W; Zhang, Y; Zhao, Y; Zheng, T; Zhong, Y; Zhou, J | 1 |
| Hao, W; Li, N; Mi, C; Wang, Q; Yu, Y | 1 |
| Dai, Z; Guan, Q; Li, W; Ma, C; Pan, T; Tang, J; Zhang, X | 1 |
| Li, WH; Tian, Y; Wang, XP; Yuan, DY | 1 |
| Jiang, L; Ma, X; Wang, Z; Wen, G; Yang, J; Yao, P; Yu, Q; Zhou, B; Zhou, L | 1 |
| Liu, T; Wu, Y; Yang, Y; Zhuang, Y | 1 |
| Chen, W; Ding, Y; Gou, Y; Hu, T; Lan, T; Li, Q; Liu, J; Ma, Y; Sun, Q; Wang, P; Yang, F; Zhang, Y | 1 |
| Chen, Y; Feng, M; Jia, Z; Liu, J; Liu, L; Xiao, H; Yan, X; Zhang, Y; Zhu, M | 1 |
| Chen, X; Ji, R; Jia, FY; Jin, WY; Wang, ZH; Yang, J | 1 |
| Fan, F; Gao, X; Li, X; Lin, JM; Meng, X; Sun, Y; Xu, N; Yi, X; Zhang, Y | 1 |
| Li, J; Ming, X; Wang, J; Xiong, L; Yu, X; Zheng, J | 1 |
| Gao, H; Liu, X; Meng, Y; Peng, Y; Tian, K; Yu, C | 1 |
| Han, J; He, Y; Huang, S; Kasim, V; Liu, C; Marcelina, O; Miyagishi, M; Nugrahaningrum, DA; Wang, G; Wu, S; Zou, M | 1 |
| Chen, XL; Hu, XJ; Li, L; Liu, HF; Nie, X; Peng, YY; Xu, XY; Zeng, Q; Zhou, WT | 1 |
| Chen, J; Ke, H; Li, W; Li, X; Ouyang, C; Shan, H; Tan, J; Tang, Y; Wang, C; Yu, L; Yu, X; Zhang, L | 1 |
| Li, Y; Li, Z; Liu, S | 1 |
| Kim, H; Kong, CS; Seo, Y | 1 |
| Liu, CC; Liu, H; Ma, L; Mao, JQ; Zhang, QQ; Zhang, YW | 1 |
| Liu, C; Qian, J; Wang, XH; Wei, BZ; Zhou, GX; Zhu, SX | 1 |
| Ding, L; Jiang, X; Peng, Z; Qiu, L; Xia, X; Yao, F; Zheng, W | 1 |
| Fan, H; Le, JW; Su, BJ; Zhu, JH | 1 |
| Bai, J; Hou, Y; Jiang, S; Meng, X; Tang, Y; Wang, X; Xie, N; Zhang, Y | 1 |
| Chen, J; Chen, L; He, B; Hu, C; Liang, T; Wen, B; Xu, K; Zhou, K | 1 |
| Cairang, N; Chen, K; Fan, F; Jiang, S; Meng, X; Sun, Z; Wang, X; Yang, L; Zhang, Y | 1 |
| Fang, X; Hu, Y; Lan, R; Qin, XY; Shu, XM; Wang, J | 1 |
| Huang, YM; Qin, ZQ; Wei, SM | 1 |
| Fang, R; Feng, Y; Huang, Y; Li, L; Li, T; Tian, X; Zhang, W; Zhang, X | 1 |
| Cai, Y; He, Y; Hu, Z; Lv, Z; Meng, X; Mou, X; Pan, Y; Zhao, X | 1 |
| Dai, GL; Meng, QH; Pan, CL; Tan, QL; Wang, XL; Xu, L; Xu, N; Zhang, CY; Zhang, HW; Zhang, Y; Zhang, ZY | 1 |
| Bao, CY; Liu, T; Wu, MZ; Xiang, Y | 1 |
| Che, Y; Chen, Y; Wang, Z; Xing, K; Yuan, S; Zheng, S; Zhong, X | 1 |
| Amevor, FK; Cui, Z; Deng, X; Du, X; Feng, J; Han, X; Jin, N; Kang, X; Li, D; Ning, Z; Shu, G; Tian, Y; Wang, X; Wang, Y; Zhang, Y; Zhao, X; Zhu, Q | 1 |
| Li, L; Li, Y; Liu, H; Wang, Z; Yan, H; Yuan, Y | 1 |
| Cheng, R; Liu, C; Meng, Y; Qian, J; Wang, P; Wang, X; Zhou, G; Zhu, S | 1 |
| Chai, H; Kang, Q; Lei, Z; Liu, Y; Qin, X | 1 |
| Jiang, L; Wang, Y; Xu, L; Yang, D; Zheng, L; Zhuang, M | 1 |
| Chen, Q; Gao, L; Lei, A; Li, J; Tian, Y; Wang, R | 1 |
| Bao, Y; Pei, D; Piao, M; Tian, S; Xu, D; Zhang, J | 1 |
| Dun, Y; Li, D; Li, H; Liu, J; Liu, S; Qiu, L; Ripley-Gonzalez, JW; You, B; Zhang, J | 1 |
| Li, L; Yao, W | 1 |
| Liang, Y; Liu, X; Lu, L; Qu, B; Zhang, C; Zheng, K | 1 |
| Chen, SY; Feng, TH; Hao, DD; Miao, HX; Shang, J; Shi, J; Wan, S; Wang, SY; Zhao, Q; Zhou, CH | 1 |
| Han, D; Jin, M; Wang, C; Wu, X; Xu, Y; Ye, R; Zhang, Q; Zhang, Z | 1 |
| Blavachinskaya, IV; Grazhdannikov, AE; Korbozova, NK; Kudrina, NO; Kulmanov, TE; Seitimova, GA; Terletskaya, NV; Tolstikova, TG; Zhukova, NA | 1 |
| Chai, Y; Chen, F; Li, Z; Liu, W; Xi, Y; Yang, P; Zhou, Q | 1 |
| Cheng, W; Li, W; Pei, T; Wang, L; Xiao, W; Yan, S; Yang, S; Zeng, Y | 1 |
| Choma, IM; Nikolaichuk, H; Stankevič, M; Studziński, M | 1 |
| Liu, T; Wu, Y; Xi, D; Yang, Y | 1 |
| Cheng, Y; Guo, Y; Liu, Y; Qian, H; Shen, F; Wang, X; Zhu, H | 1 |
| Akashi, T; Fuji, Y; Hirai, MY; Matsufuji, H; Ohtsuki, T; Uchida, K | 1 |
| Du, X; Feng, W; Lin, X; Shen, N; Song, L; Yang, X; Zhang, S | 1 |
| Fang, DM; Guo, YJ; Li, Y; Liang, ZF; Liu, YL; Miao, L; Tao, L; Yang, ZJ | 1 |
| Feng, M; Jin, G; Ma, M; Yang, C; Zhen, L | 1 |
| Chen, L; Chen, W; Gao, T; Gu, X; Li, X; Liu, J; Liu, Z; Lu, Z; Ouyang, L; Xiao, Y; Xiong, D; Zhan, Y; Zhou, Y | 1 |
| Fahmi, OA; Kasprzyk, PG; Tremaine, L; Weng, JK | 1 |
| Chen, XD; Ding, Y; Li, S; Long, ZY; Lu, XM; Peng, YY; Tang, C; Wang, HY; Wang, YT; Wei, JX | 1 |
21 review(s) available for rhodioloside and glucose, (beta-d)-isomer
| Article | Year |
|---|---|
[Experimental analysis of therapeutic properties of Rhodiola rosea L. and its possible application in medicine].
Topics: Adaptation, Physiological; Adult; Animals; Anti-Arrhythmia Agents; Antidepressive Agents; Antineoplastic Agents; Antioxidants; Arrhythmias, Cardiac; Central Nervous System; Clinical Trials as Topic; Depression; Glucosides; Humans; Lymnaea; Medicine, Traditional; Mental Fatigue; Neoplasms; Phenols; Phenylethyl Alcohol; Phytotherapy; Plant Extracts; Plant Preparations; Rats; Resins, Plant; Rhodiola | 2004 |
[Salidroside biosynthesis pathway: the initial reaction and glycosylation of tyrosol].
Topics: Genetic Engineering; Glucosides; Glycosylation; Phenols; Phenylethyl Alcohol; Rhodiola; Tyrosine; Tyrosine Decarboxylase | 2012 |
[Advance in studies on pharmacological effect of salidroside on nervous system diseases].
Topics: Animals; Apoptosis Regulatory Proteins; Drugs, Chinese Herbal; Glucosides; Humans; Nervous System Diseases; Phenols; Rhodiola | 2012 |
[Research progress of alternative production approaches of salidroside].
Topics: Biosynthetic Pathways; Cell Culture Techniques; Crassulaceae; Glucosides; Humans; Molecular Structure; Phenols; Plant Extracts | 2013 |
Rhodiola rosea L. and Alzheimer's Disease: From Farm to Pharmacy.
Topics: Alzheimer Disease; Clinical Trials as Topic; Cognition Disorders; Disaccharides; Glucosides; Humans; Neuroprotective Agents; Oxidative Stress; p21-Activated Kinases; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Roots; Plants, Medicinal; Rhodiola | 2016 |
Immunmodulatory and Antiproliferative Properties of Rhodiola Species.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Proliferation; Glucosides; Humans; Immunologic Factors; Phenols; Plant Extracts; Rhodiola; Species Specificity | 2016 |
Pharmacological activities, mechanisms of action, and safety of salidroside in the central nervous system.
Topics: Animals; Apoptosis; Central Nervous System; Glucosides; Humans; Inflammation; Nervous System Diseases; Neuroprotective Agents; Oxidative Stress; Phenols | 2018 |
M1 and M2 macrophage polarization and potentially therapeutic naturally occurring compounds.
Topics: Animals; Biological Products; Cell Differentiation; Curcumin; Cytokines; Glucosides; Humans; Hydrolyzable Tannins; Luteolin; Macrophage Activation; Macrophages; Phenols; Th1 Cells; Th2 Cells | 2019 |
Beneficial Effects of Rhodiola and Salidroside in Diabetes: Potential Role of AMP-Activated Protein Kinase.
Topics: AMP-Activated Protein Kinases; Animals; Biomarkers; Clinical Studies as Topic; Diabetes Mellitus; Drug Evaluation, Preclinical; Energy Metabolism; Enzyme Activation; Glucosides; Humans; Hypoglycemic Agents; Molecular Targeted Therapy; Oxidative Stress; Phenols; Plant Extracts; Rhodiola; Signal Transduction; Structure-Activity Relationship; Treatment Outcome | 2019 |
Research progress on SIRT1 and sepsis.
Topics: Animals; Glucosides; Humans; Inflammation; Phenols; Resveratrol; Sepsis; Signal Transduction; Sirtuin 1; Xanthones | 2019 |
Rhodiola and salidroside in the treatment of metabolic disorders.
Topics: AMP-Activated Protein Kinases; Anti-Inflammatory Agents; Antioxidants; Autophagy; Glucosides; Humans; Metabolic Diseases; Mitochondria; Phenols; Plant Extracts; Rhodiola | 2019 |
Salidroside inhibits MAPK, NF-κB, and STAT3 pathways in psoriasis-associated oxidative stress via SIRT1 activation.
Topics: Animals; Glucosides; Humans; Mitogen-Activated Protein Kinases; NF-kappa B; Oxidative Stress; Phenols; Sirtuin 1; STAT3 Transcription Factor | 2019 |
Advances in Research on Anticancer Properties of Salidroside.
Topics: Glucosides; Liver; Phenols; Rhodiola | 2021 |
Salidroside - Can it be a Multifunctional Drug?
Topics: Animals; Antineoplastic Agents; Diabetes Mellitus; Glucosides; Humans; Hypoglycemic Agents; Hypoxia; Metabolic Diseases; Neoplasms; Neurodegenerative Diseases; Neuroprotective Agents; Phenols; Rhodiola; Wounds and Injuries | 2020 |
Salidroside as a potential neuroprotective agent for ischemic stroke: a review of sources, pharmacokinetics, mechanism and safety.
Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Glucosides; Humans; Ischemic Stroke; Neuroprotective Agents; Phenols; Treatment Outcome | 2020 |
Nutraceutical based SIRT3 activators as therapeutic targets in Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Animals; Biphenyl Compounds; Dietary Supplements; Drug Delivery Systems; Enzyme Inhibitors; Glucosides; Humans; Hydrazines; Indazoles; Lignans; Neuroprotection; Phenols; Sirtuin 3 | 2021 |
Salidroside: A review of its recent advances in synthetic pathways and pharmacological properties.
Topics: Animals; Central Nervous System; Diabetes Mellitus; Glucosides; Humans; Neoplasms; Phenols; Rhodiola | 2021 |
The Therapeutic Effects and Mechanisms of Salidroside on Cardiovascular and Metabolic Diseases: An Updated Review.
Topics: Animals; Cardiovascular Diseases; Glucosides; Humans; Metabolic Diseases; Phenols | 2021 |
The Therapeutic Potential of Salidroside for Parkinson's Disease.
Topics: Animals; Glucosides; Parkinson Disease; Phosphatidylinositol 3-Kinases; Signal Transduction | 2023 |
Salidroside in the Treatment of NAFLD/NASH.
Topics: Fibrosis; Glucosides; Humans; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease | 2022 |
Pharmacological effects of salidroside on central nervous system diseases.
Topics: Central Nervous System Diseases; Glucosides; Phenols; Rhodiola | 2022 |
2 trial(s) available for rhodioloside and glucose, (beta-d)-isomer
| Article | Year |
|---|---|
Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
Topics: Adult; Cognition; Cross-Over Studies; Double-Blind Method; Fatigue; Female; Glucosides; Humans; Male; Phenols; Phytotherapy; Plant Extracts; Plants, Medicinal; Workload | 2000 |
Protective effects of salidroside on epirubicin-induced early left ventricular regional systolic dysfunction in patients with breast cancer.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antioxidants; Breast Neoplasms; Dose-Response Relationship, Drug; Double-Blind Method; Echocardiography; Epirubicin; Female; Glucosides; Humans; Middle Aged; Phenols; Reactive Oxygen Species; Rhodiola; Ventricular Dysfunction, Left | 2012 |
531 other study(ies) available for rhodioloside and glucose, (beta-d)-isomer
| Article | Year |
|---|---|
Synthesis and identification of a novel derivative of salidroside as a selective, competitive inhibitor of monoamine oxidase B with enhanced neuroprotective properties.
Topics: Amino Acid Sequence; Animals; Apoptosis; Biological Transport; Blood-Brain Barrier; Complement C3; Drug Evaluation, Preclinical; Gene Expression Regulation; Glucosides; Humans; Male; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; PC12 Cells; Phenols; Protein Binding; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Structure-Activity Relationship | 2021 |
[HPLC determination of salidroside in the roots of Rhodiola genus plants].
Topics: Chromatography, High Pressure Liquid; Glucosides; Phenols; Plants, Medicinal; Species Specificity | 1992 |
[Chemical constituents of Rhodiola kirilowii (Reg.) Reg].
Topics: Drugs, Chinese Herbal; Glucosides; Phenols; Phenylethyl Alcohol; Sitosterols | 1992 |
[Effect of salidroside on cultured myocardial cells anoxia/reoxygenation injuries].
Topics: Animals; Cell Hypoxia; Cells, Cultured; Female; Glucosides; Heart Rate; L-Lactate Dehydrogenase; Male; Myocardium; Phenols; Plants, Medicinal; Rats; Rats, Sprague-Dawley | 1993 |
[Studies on the chemical constituents of Rhodiola fastigita].
Topics: Flavonoids; Glucosides; Glycosides; Magnoliopsida; Molecular Structure; Phenols; Plants, Medicinal | 1996 |
Quantitative determination of salidroside and tyrosol from the underground part of Rhodiola rosea by high performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Glucosides; Phenols; Phenylethyl Alcohol; Plants, Medicinal | 2000 |
[Phenylethanoid glucosides from flos Buddlejae].
Topics: Drugs, Chinese Herbal; Glucosides; Glycosides; Magnoliopsida; Molecular Structure; Phenols; Plants, Medicinal | 1997 |
[Determination of salidroside in eight Rhodiola species by TLC-UV spectrometry].
Topics: Chromatography, Thin Layer; Drugs, Chinese Herbal; Glucosides; Magnoliopsida; Phenols; Plant Roots; Plants, Medicinal; Spectrophotometry, Ultraviolet | 1998 |
Lignan and phenylpropanoid glycosides from Phillyrea latifolia and their in vitro anti-inflammatory activity.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Blood Platelets; Cells, Cultured; Cinnamates; Dinoprostone; Drug Interactions; Eicosanoids; Female; Glucosides; Glycosides; Humans; Ionophores; Leukotriene C4; Macrophages, Peritoneal; Magnoliopsida; Male; Mice; Phenols; Phenylpropionates; Plants, Medicinal; Thromboxane B2 | 2001 |
[Quantitative analysis of salidroside and lotaustralin in Rhodiola by gas chromatography].
Topics: Chromatography, Gas; Drugs, Chinese Herbal; Glucosides; Magnoliopsida; Nitriles; Phenols; Plants, Medicinal | 1998 |
Preparative isolation and purification of salidroside from the Chinese medicinal plant Rhodiola sachalinensis by high-speed counter-current chromatography.
Topics: Chromatography, High Pressure Liquid; Countercurrent Distribution; Glucosides; Phenols; Plants, Medicinal; Spectrophotometry, Ultraviolet | 2001 |
Separation of salidroside from Rhodiola crenulata by high-speed counter-current chromatography.
Topics: Countercurrent Distribution; Glucosides; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phenols; Plant Extracts; Rhodiola | 2002 |
Effects of long-term, elevated ultraviolet-B radiation on phytochemicals in the bark of silver birch (Betula pendula).
Topics: Betula; Catechin; Glucose; Glucosides; Phenols; Plant Bark; Raffinose; Sucrose; Terpenes; Trees; Ultraviolet Rays | 2002 |
Formation of benzoquinol moiety in cornoside by salidroside mono-oxygenase, a cytochrome P450 enzyme, from Abeliophyllum distichumcell suspension cultures.
Topics: Benzoquinones; Carbon Monoxide; Cells, Cultured; Cyclohexanones; Cytochrome c Group; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Glucosides; Hydrogen-Ion Concentration; Miconazole; Mixed Function Oxygenases; NADP; Oleaceae; Oxygen; Phenols; Reactive Oxygen Species | 2003 |
Hepatoprotective phenolic constituents of Rhodiola sachalinensis on tacrine-induced cytotoxicity in Hep G2 cells.
Topics: Cell Division; Dose-Response Relationship, Drug; Flavonoids; Glucosides; Humans; Kaempferols; Molecular Structure; Phenols; Plant Extracts; Plant Roots; Rhodiola; Tacrine; Tumor Cells, Cultured | 2003 |
Determination of p-tyrosol and salidroside in three samples of Rhodiola crenulata and one of Rhodiola kirilowii by capillary zone electrophoresis.
Topics: Calibration; Electrophoresis, Capillary; Glucosides; Phenols; Phenylethyl Alcohol; Rhodiola; Species Specificity | 2003 |
Comparison of electrospray ionization and atmospheric pressure chemical ionization techniques in the analysis of the main constituents from Rhodiola rosea extracts by liquid chromatography/mass spectrometry.
Topics: Atmospheric Pressure; Calibration; Chromatography, Liquid; Glucosides; Medicine, Chinese Traditional; Phenols; Propanols; Reproducibility of Results; Rhodiola; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2003 |
High yield production of salidroside in the suspension culture of Rhodiola sachalinensis.
Topics: Bioreactors; Cell Culture Techniques; Cell Division; Cells, Cultured; Culture Media; Drugs, Chinese Herbal; Glucosides; Hydrogen-Ion Concentration; Phenols; Rhodiola | 2003 |
Phenolic components of Olea europaea--isolation of tyrosol derivatives.
Topics: Antioxidants; Glucosides; Olea; Phenols; Phenylethyl Alcohol | 2004 |
[Seasonal variations in biomass and salidroside content in roots of Rhodiola sachalinensis as affected by gauze and red film shading].
Topics: Biomass; Glucosides; Light; Phenols; Plant Roots; Rhodiola; Seasons | 2004 |
[Effects of salidroside on carbohydrate metabolism and differentiation of 3T3-L1 adipocytes].
Topics: 3T3-L1 Cells; Adipocytes; Animals; Carbohydrate Metabolism; Carrier Proteins; Cell Proliferation; Down-Regulation; Drugs, Chinese Herbal; Gene Expression; Glucose; Glucosides; Hypoglycemic Agents; Mice; Phenols; PPAR gamma; RNA, Messenger; Rosiglitazone; Spectrophotometry; Steroid Isomerases; Thiazolidinediones | 2004 |
[Protective effects of salidroside on injury induced by hypoxia/hypoglycemia in cultured neurons].
Topics: Apoptosis; Calcium; Cell Hypoxia; Glucosides; Humans; Hypoglycemia; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Phenols; Plants, Medicinal; Rhodiola | 2004 |
[Effects of plant growth substances on induction and culture of callus from Rhodiola quadrifida].
Topics: Culture Media; Glucosides; Phenols; Plant Growth Regulators; Plant Stems; Plants, Medicinal; Rhodiola; Tissue Culture Techniques | 2005 |
[Effect of salidroside on mitochondria injury induced by sodium azide].
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Glucosides; Humans; Male; Membrane Potentials; Mitochondria; Neuroblastoma; Oxidation-Reduction; Phenols; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rhodiola; Sodium Azide | 2005 |
[Effect of salidroside on bone marrow cell cycle and expression of apoptosis-related proteins in bone marrow cells of bone marrow depressed anemia mice].
Topics: Anemia, Aplastic; Animals; Apoptosis; bcl-2-Associated X Protein; Bone Marrow Cells; Cell Cycle; Dose-Response Relationship, Drug; Glucosides; Hematopoiesis; Hematopoietic Stem Cells; Male; Mice; Mice, Inbred BALB C; Phenols; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rhodiola | 2005 |
[Study on effects of salidroside on lipid peroxidation on oxidative stress in rat hepatic stellate cells].
Topics: Animals; Cell Proliferation; Cells, Cultured; Collagen Type I; Glucosides; Hepatocytes; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Oxidative Stress; Phenols; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rhodiola | 2005 |
[Determination of salidroside and p-tyrosol in Hongjingtian for injection(freezing-dry) by SPE-HPLC].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Injections; Phenols; Phenylethyl Alcohol; Plants, Medicinal; Rhodiola; Temperature | 2006 |
Rhodiolosides A-E, monoterpene glycosides from Rhodiola rosea.
Topics: Carbohydrate Sequence; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Glucosides; Glycosides; Humans; Molecular Sequence Data; Molecular Structure; Monoterpenes; Phenols; Plant Roots; Rhodiola | 2006 |
[Study on the extraction process for salidroside and p-tyrosol in Rhodiola crenulata].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Ethanol; Glucosides; Phenols; Phenylethyl Alcohol; Plants, Medicinal; Rhodiola; Technology, Pharmaceutical; Time Factors | 2006 |
[Effects of salidroside on bone marrow matrix metalloproteinases of bone marrow depressed anemic mice].
Topics: Anemia, Aplastic; Animals; Bone Marrow; Glucosides; Hematopoiesis; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Phenols | 2006 |
Rhodiola rosea L. extract reduces stress- and CRF-induced anorexia in rats.
Topics: Animals; Anorexia; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Escherichia coli; Feeding Behavior; Fluoxetine; Glucosides; Immobilization; Lipopolysaccharides; Male; Phenols; Plant Extracts; Plant Roots; Rats; Rats, Wistar; Rhodiola; Stress, Psychological | 2007 |
Pharmacological studies on the sedative and hypnotic effect of salidroside from the Chinese medicinal plant Rhodiola sachalinensis.
Topics: Animals; Drug Synergism; Glucosides; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Pentobarbital; Phenols; Phytotherapy; Plant Extracts; Rhodiola; Sleep | 2007 |
Salidroside production by hairy roots of Rhodiola sachalinensis obtained after transformation with Agrobacterium rhizogenes.
Topics: Agaricales; Aspergillus niger; Biomass; Ganoderma; Glucosides; Phenols; Phenylalanine; Phenylethyl Alcohol; Plant Growth Regulators; Plant Roots; Plants, Genetically Modified; Rhizobium; Rhodiola; Transformation, Genetic; Tyrosine | 2007 |
Molecular cloning and overexpression of a novel UDP-glucosyltransferase elevating salidroside levels in Rhodiola sachalinensis.
Topics: Amino Acid Sequence; Cloning, Molecular; Gene Expression Regulation, Plant; Genome, Plant; Glucosides; Glucosyltransferases; Molecular Sequence Data; Molecular Structure; Phenols; Phylogeny; Plant Proteins; Rhodiola | 2007 |
Protective effects of salidroside on hydrogen peroxide-induced apoptosis in SH-SY5Y human neuroblastoma cells.
Topics: Antioxidants; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Calcium; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucosides; Heme Oxygenase-1; Humans; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Neuroblastoma; Neurons; Oxidative Stress; Peroxidases; Peroxiredoxins; Phenols; Proto-Oncogene Proteins c-bcl-2; Rhodiola; Thioredoxins | 2007 |
X-ray crystal structure and antioxidant activity of salidroside, a phenylethanoid glycoside.
Topics: Antioxidants; Cistanche; Crystallography, X-Ray; Free Radical Scavengers; Glucosides; Glycosides; Phenols; Plant Extracts; Plant Stems | 2007 |
Effect of different preparation methods on physicochemical properties of salidroside liposomes.
Topics: Chemical Phenomena; Chemistry, Physical; Drug Stability; Freezing; Glucosides; Hot Temperature; Liposomes; Particle Size; Phenols; Sonication | 2007 |
Activity of compounds from Chinese herbal medicine Rhodiola kirilowii (Regel) Maxim against HCV NS3 serine protease.
Topics: Acylation; Animals; Antiviral Agents; Chlorocebus aethiops; COS Cells; Drugs, Chinese Herbal; Glucosides; Hepacivirus; Hepatitis C; Methylation; Phenols; Rhizome; Rhodiola; Viral Nonstructural Proteins | 2007 |
Simultaneous determination of salidroside and tyrosol in extracts of Rhodiola L. by microwave assisted extraction and high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Microwaves; Phenols; Phenylethyl Alcohol; Plant Roots; Reference Standards; Reproducibility of Results; Rhodiola; Sensitivity and Specificity | 2007 |
Quantitative determination of salidroside in rat plasma by on-line solid-phase extraction integrated with high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Administration, Oral; Animals; Benzyl Alcohols; Calibration; Chromatography, High Pressure Liquid; Drug Stability; Drugs, Chinese Herbal; Glucosides; Injections, Intravenous; Male; Online Systems; Phenols; Rats; Rats, Sprague-Dawley; Reference Standards; Rhodiola; Sensitivity and Specificity; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2007 |
Evaluation of biologically active compounds in roots and rhizomes of Rhodiola rosea L. cultivated in Lithuania.
Topics: Chromatography, Thin Layer; Data Interpretation, Statistical; Densitometry; Ethanol; Glucosides; Lithuania; Phenols; Plant Extracts; Plant Roots; Resins, Plant; Rhizome; Rhodiola; Time Factors | 2007 |
Development of an HPLC method for the determination of salidroside in beagle dog plasma after administration of salidroside injection: application to a pharmacokinetics study.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Dogs; Female; Glucosides; Injections, Intravenous; Male; Molecular Structure; Phenols; Sensitivity and Specificity | 2007 |
Comparative study of Rhodiola preparations on behavioral despair of rats.
Topics: Administration, Oral; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Depression; Disaccharides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Glucosides; Male; Molecular Structure; Phenols; Phenylethyl Alcohol; Piper nigrum; Plant Preparations; Plant Roots; Rats; Rats, Wistar; Rhodiola; Stress, Physiological | 2008 |
Development and validation of a liquid chromatographic/electrospray ionization mass spectrometric method for the determination of salidroside in rat plasma: application to the pharmacokinetics study.
Topics: Animals; Chromatography, Liquid; Glucosides; Molecular Structure; Phenols; Rats; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2008 |
Environmentally benign synthesis of natural glycosides using apple seed meal as green and robust biocatalyst.
Topics: Aluminum Oxide; Catalysis; Chromatography, High Pressure Liquid; Glucosidases; Glucosides; Glycosides; Malus; Microscopy, Electron, Scanning; Molecular Structure; Phenols; Seeds | 2008 |
Effects of overexpression of endogenous phenylalanine ammonia-lyase (PALrs1) on accumulation of salidroside in Rhodiola sachalinensis.
Topics: Amino Acid Sequence; Coumaric Acids; Gene Expression; Glucosides; Molecular Sequence Data; Multigene Family; Phenols; Phenylalanine Ammonia-Lyase; Phenylethyl Alcohol; Plants, Genetically Modified; Propionates; Rhodiola; Sequence Analysis, DNA; Tyrosine | 2008 |
Neuroprotective effects of salidroside in the PC12 cell model exposed to hypoglycemia and serum limitation.
Topics: Animals; Annexin A5; bcl-2-Associated X Protein; Caspase 3; Cell Death; Flow Cytometry; Gene Expression Regulation; Glucosides; Hypoglycemia; Membrane Potential, Mitochondrial; Microscopy, Confocal; Models, Biological; Neuroprotective Agents; PC12 Cells; Phenols; Propidium; Rats; Reactive Oxygen Species; RNA, Messenger; Serum | 2008 |
Salidroside stimulated glucose uptake in skeletal muscle cells by activating AMP-activated protein kinase.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Cell Line; Enzyme Activation; Glucose; Glucosides; Insulin; Multienzyme Complexes; Muscle, Skeletal; Phenols; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Signal Transduction | 2008 |
Protective effects of salidroside against acetaminophen-induced toxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Caspase 3; Chemical and Drug Induced Liver Injury; Glucosides; Glutathione; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Oxidative Stress; Phenols; Rhodiola; Tumor Necrosis Factor-alpha | 2008 |
Salidroside attenuates glutamate-induced apoptotic cell death in primary cultured hippocampal neurons of rats.
Topics: Animals; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Embryo, Mammalian; Flow Cytometry; Glucosides; Glutamic Acid; Hippocampus; In Situ Nick-End Labeling; Neurons; Neuroprotective Agents; Phenols; Rats; Rats, Sprague-Dawley | 2008 |
The influence of Rhodiola quadrifida 50% hydro-alcoholic extract and salidroside on tumor-induced angiogenesis in mice.
Topics: Animals; Dose-Response Relationship, Drug; Female; Glucosides; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Phenols; Phytotherapy; Plant Extracts; Random Allocation; Rhodiola; Skin Neoplasms | 2008 |
Synthesis of novel salidroside esters by lipase-mediated acylation with various functional acyl groups.
Topics: Acylation; Enzymes, Immobilized; Esters; Fungal Proteins; Glucosides; Lipase; Phenols | 2008 |
[Effect of salidroside on salivary adenoid cystic carcinoma cells in vitro].
Topics: Apoptosis; Carcinoma, Adenoid Cystic; Cell Line, Tumor; Cell Proliferation; Glucosides; Humans; Immunohistochemistry; In Vitro Techniques; Phenols; Salivary Gland Neoplasms | 2008 |
Salidroside inhibits H2O2-induced apoptosis in PC12 cells by preventing cytochrome c release and inactivating of caspase cascade.
Topics: Animals; Apoptosis; Bisbenzimidazole; Caspases; Cell Survival; Cytochromes c; DNA Fragmentation; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Enzyme Activation; Fluorescent Dyes; Formazans; Glucosides; Hydrogen Peroxide; L-Lactate Dehydrogenase; PC12 Cells; Phenols; Protective Agents; Rats; RNA, Messenger; Tetrazolium Salts | 2008 |
The in vitro and in vivo antiviral effects of salidroside from Rhodiola rosea L. against coxsackievirus B3.
Topics: Animals; Antiviral Agents; Coxsackievirus Infections; Cytokines; Enterovirus B, Human; Enzymes; Glucosides; Heart; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Myocardium; Phenols; Phytotherapy; Rats; Rats, Sprague-Dawley; Rhodiola; RNA, Messenger; Superoxide Dismutase | 2009 |
[Studies on chemical constituents from stem barks of Fraxinus paxiana].
Topics: Coumarins; Esculin; Fraxinus; Furans; Glucosides; Glycosides; Mannitol; Methanol; Phenols; Plant Bark; Triterpenes; Umbelliferones | 2008 |
Preparative purification of salidroside from Rhodiola rosea by two-step adsorption chromatography on resins.
Topics: Adsorption; Chromatography, High Pressure Liquid; Crystallization; Glucosides; Kinetics; Molecular Structure; Phenols; Rhodiola | 2009 |
HPLC analysis, semi-preparative HPLC preparation and identification of three impurities in salidroside bulk drug.
Topics: Chromatography, High Pressure Liquid; Drug Contamination; Glucosides; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phenols; Reproducibility of Results; Rhodiola; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 2009 |
Salidroside from Rhodiola sachalinensis protects neuronal PC12 cells against cytotoxicity induced by amyloid-beta.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Cell Death; Cell Survival; Cytoprotection; Dose-Response Relationship, Drug; Glucosides; Lipid Peroxidation; Malondialdehyde; Neurons; Oxidative Stress; PC12 Cells; Phenols; Plant Roots; Rats; Reactive Oxygen Species; Rhodiola | 2003 |
[Effects of salidroside-pretreatment on neuroethology of rats after global cerebral ischemia-reperfusion].
Topics: Animals; Brain; Brain Ischemia; Glucosides; Ischemic Preconditioning; Male; Malondialdehyde; Maze Learning; Phenols; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase | 2009 |
[Protective effects of salidroside on oxidative damage in fatigue mice].
Topics: Animals; Creatine Kinase; Creatine Kinase, MB Form; Fatigue; Glucosides; Glutathione Peroxidase; L-Lactate Dehydrogenase; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Muscle, Skeletal; Myocardium; Oxidative Stress; Phenols; Superoxide Dismutase | 2009 |
Salidroside protects cardiomyocyte against hypoxia-induced death: a HIF-1alpha-activated and VEGF-mediated pathway.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Hypoxia; Cell Survival; Dose-Response Relationship, Drug; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Myocytes, Cardiac; Necrosis; Phenols; Protein Transport; Rats; Rats, Sprague-Dawley; Rhodiola; Up-Regulation; Vascular Endothelial Growth Factor A | 2009 |
Cardioprotection of salidroside from ischemia/reperfusion injury by increasing N-acetylglucosamine linkage to cellular proteins.
Topics: Acetylglucosamine; Adenosine Triphosphate; Alloxan; Animals; Apoptosis; Biological Transport; Calcium; Cardiotonic Agents; Cell Survival; Cytosol; Glucose; Glucosides; In Vitro Techniques; Myocytes, Cardiac; N-Acetylglucosaminyltransferases; Phenols; Proteins; Rats; Reperfusion Injury | 2009 |
Production of Th1- and Th2-dependent cytokines induced by the Chinese medicine herb, Rhodiola algida, on human peripheral blood monocytes.
Topics: Adult; Chromatography, High Pressure Liquid; Cytokines; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Glucosides; Humans; Immunologic Factors; In Vitro Techniques; Interleukins; Male; Middle Aged; Monocytes; Phenols; Plant Extracts; Rhodiola; Th1 Cells; Th2 Cells; Young Adult | 2009 |
Effects of Radix et Rhizoma Rhodiolae Kirilowii on expressions of von Willebrand factor, hypoxia-inducible factor 1 and vascular endothelial growth factor in myocardium of rats with acute myocardial infarction.
Topics: Animals; Drugs, Chinese Herbal; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Myocardial Infarction; Myocardium; Phenols; Phytotherapy; Rats; Rats, Wistar; Rhizome; Rhodiola; RNA, Messenger; Vascular Endothelial Growth Factor A; von Willebrand Factor | 2009 |
Salidroside, the main active compound of Rhodiola plants, inhibits high glucose-induced mesangial cell proliferation.
Topics: Cell Line; Cell Proliferation; Glucose; Glucosides; Humans; Mesangial Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phenols; Phosphorylation; Rhodiola; Transforming Growth Factor beta1 | 2009 |
[Salidroside protects the hypothalamic-pituitary-gonad axis of male rats undergoing negative psychological stress in experimental navigation and intensive exercise].
Topics: Animals; Glucosides; Hypothalamo-Hypophyseal System; Male; Phenols; Physical Conditioning, Animal; Pituitary Gland; Rats; Rats, Sprague-Dawley; Rhodiola; Stress, Psychological | 2009 |
Isolation and genotype-dependent, organ-specific expression analysis of a Rhodiola rosea cDNA encoding tyrosine decarboxylase.
Topics: Amino Acid Sequence; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genotype; Glucosides; Molecular Sequence Data; Phenols; Plant Proteins; Polymerase Chain Reaction; Rhodiola; Sequence Alignment; Tyrosine Decarboxylase | 2009 |
Protective effect of salidroside against H2O2-induced cell apoptosis in primary culture of rat hippocampal neurons.
Topics: Animals; Apoptosis; Caspase 3; Cells, Cultured; Glucosides; Hippocampus; Hydrogen Peroxide; In Situ Nick-End Labeling; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Phenols; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Rhodiola | 2009 |
Decreased mitochondrial superoxide levels and enhanced protection against paraquat in Drosophila melanogaster supplemented with Rhodiola rosea.
Topics: Animals; Antioxidants; Catalase; Cytoprotection; Disaccharides; Down-Regulation; Drosophila melanogaster; Female; Fertility; Glucosides; Hydrogen Peroxide; Longevity; Male; Mitochondria; Oxidants; Oxidative Stress; Paraquat; Phenols; Plant Extracts; Plant Roots; Rhodiola; Superoxide Dismutase; Superoxides | 2009 |
Protective effects of salidroside on endothelial cell apoptosis induced by cobalt chloride.
Topics: Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cell Culture Techniques; Cell Hypoxia; Cell Line; Cell Survival; Cobalt; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Flow Cytometry; Glucosides; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Molecular Structure; Phenols; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2009 |
Phytochemical characterization of an adaptogenic preparation from Rhodiola heterodonta.
Topics: Animals; Catechin; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Liquid; Ethanol; Glucosides; Hypoxia; Mass Spectrometry; Mice; Phenols; Phenylethyl Alcohol; Plant Preparations; Proanthocyanidins; Rhodiola | 2009 |
Involvement of ERK1/2 pathway in neuroprotection by salidroside against hydrogen peroxide-induced apoptotic cell death.
Topics: Animals; Antioxidants; Apoptosis; Cell Differentiation; Enzyme Inhibitors; Flavonoids; Glucosides; Hydrogen Peroxide; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molecular Structure; Nerve Growth Factor; Neuroprotective Agents; Oxidants; PC12 Cells; Phenols; Rats | 2010 |
Hepatoprotective effects of salidroside on fulminant hepatic failure induced by D-galactosamine and lipopolysaccharide in mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Caspase 3; Disease Models, Animal; Dose-Response Relationship, Drug; Galactosamine; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Oxidative Stress; Phenols; Tumor Necrosis Factor-alpha | 2009 |
Evaluation of salidroside in vitro and in vivo genotoxicity.
Topics: Animals; Antiviral Agents; CHO Cells; Cricetinae; Cricetulus; Female; Glucosides; Male; Medicine, Chinese Traditional; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Microsomes, Liver; Mutagenesis; Mutagens; Phenols; Rhodiola; Salmonella typhimurium | 2010 |
A preliminary study: the anti-proliferation effect of salidroside on different human cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Drug Screening Assays, Antitumor; Gene Expression; Glucosides; Humans; Phenols | 2010 |
[Effects of salidroside on tubular epithelial to myofibroblast transition under cobaltous chloride induced hypoxic status].
Topics: Animals; Cell Differentiation; Cell Hypoxia; Cell Line; Cobalt; Epithelial Cells; Glucosides; Kidney Tubules; Myofibroblasts; Phenols; Rats; Rhodiola | 2010 |
Short communication: Influence of pasteurization on the active compounds in medicinal plants to be used in dairy products.
Topics: Animals; Cattle; Dairy Products; Disaccharides; Eleutherococcus; Food Preservation; Ginsenosides; Glucosides; Milk; Panax; Phenols; Plant Extracts; Plant Roots; Plants, Medicinal; Rhodiola; Yogurt | 2010 |
Protective role of salidroside against aging in a mouse model induced by D-galactose.
Topics: Aging, Premature; Animals; Cerebral Cortex; Drugs, Chinese Herbal; Galactose; Glial Fibrillary Acidic Protein; Glucosides; Glycation End Products, Advanced; Interleukin-2; Memory; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Growth Factors; Nerve Tissue Proteins; Phenols; Spleen; T-Lymphocytes | 2010 |
Salidroside induces cell-cycle arrest and apoptosis in human breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Glucosides; Humans; Phenols | 2010 |
Salidroside attenuates hypoxia-induced abnormal processing of amyloid precursor protein by decreasing BACE1 expression in SH-SY5Y cells.
Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Blotting, Western; Cell Hypoxia; Cell Line; Enzyme-Linked Immunosorbent Assay; Gene Expression; Glucosides; Humans; Hypoxia-Inducible Factor 1; Neurons; Neuroprotective Agents; Phenols; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
In-vitro promoted differentiation of mesenchymal stem cells towards hepatocytes induced by salidroside.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Female; Glucosides; Hepatocytes; Mesenchymal Stem Cells; Phenols; Phosphatidylinositol 3-Kinase; Rats; Rats, Sprague-Dawley; Rhodiola; Signal Transduction | 2010 |
Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells.
Topics: Amyloid beta-Peptides; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; DNA Primers; Flow Cytometry; Glucosides; Heme Oxygenase-1; Humans; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondrial Membranes; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phenols; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sincalide; Trypan Blue | 2010 |
Synergistic effects of rMSCs and salidroside on the experimental hepatic fibrosis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; beta Catenin; Blotting, Western; Cadherins; Cell Differentiation; Cell Proliferation; Collagen; Fluorescent Antibody Technique; Glucosides; Hepatocytes; Hydroxyproline; Liver; Liver Cirrhosis; Liver Function Tests; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Phenols; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2010 |
Effect of salidroside, active principle of Rhodiola rosea extract, on binge eating.
Topics: Analysis of Variance; Animals; Bulimia; Disease Models, Animal; Feeding Behavior; Female; Glucosides; Phenols; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhodiola; Stress, Psychological | 2010 |
Salidroside promotes erythropoiesis and protects erythroblasts against oxidative stress by up-regulating glutathione peroxidase and thioredoxin.
Topics: Altitude Sickness; Cell Line; Cell Proliferation; Erythroblasts; Erythropoiesis; Ethnopharmacology; Glucosides; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Medicine, Chinese Traditional; Medicine, Tibetan Traditional; Oxidative Stress; Phenols; Phytotherapy; Plants, Medicinal; Reactive Oxygen Species; Rhodiola; Thioredoxins; Up-Regulation | 2011 |
Synthesis, biological activity of salidroside and its analogues.
Topics: Animals; Cell Line, Tumor; Cell Survival; Glucosides; Phenols; Plants, Medicinal; Rats; Rhodiola | 2010 |
Salidroside attenuates apoptosis in ischemic cardiomyocytes: a mechanism through a mitochondria-dependent pathway.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cells, Cultured; Disease Models, Animal; Glucosides; Male; Membrane Potentials; Mitochondria, Heart; Myocardial Ischemia; Myocytes, Cardiac; Phenols; Phosphorylation; Phytotherapy; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rhodiola; Up-Regulation | 2010 |
[Studies on the chemical constituents of Rhodiola rosea].
Topics: Flavanones; Glucosides; Glycosides; Kaempferols; Magnetic Resonance Spectroscopy; Molecular Structure; Phenols; Plants, Medicinal; Rhizome; Rhodiola; Sucrose | 2010 |
Salidroside protects against MPP(+)-induced apoptosis in PC12 cells by inhibiting the NO pathway.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Glucosides; Membrane Potential, Mitochondrial; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Oxidative Stress; Parkinsonian Disorders; PC12 Cells; Phenols; Rats; Reactive Oxygen Species; Signal Transduction | 2011 |
Effects of 2-aminoindan-2-phosphonic acid treatment on the accumulation of salidroside and four phenylethanoid glycosides in suspension cell culture of Cistanche deserticola.
Topics: Catechols; Chromatography, High Pressure Liquid; Cistanche; Glucosides; Glycosides; Indans; Organophosphonates; Phenols | 2011 |
Determination of salidroside and tyrosol in Rhodiola by capillary electrophoresis with graphene/poly(urea-formaldehyde) composite modified electrode.
Topics: Drugs, Chinese Herbal; Electrodes; Electrophoresis, Capillary; Formaldehyde; Glucosides; Graphite; Microscopy, Electron, Scanning; Phenols; Phenylethyl Alcohol; Polymers; Rhodiola; Urea | 2011 |
In vivo Th1 and Th2 cytokine modulation effects of Rhodiola rosea standardised solution and its major constituent, salidroside.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Cytokines; Dose-Response Relationship, Immunologic; Female; Glucosides; Interferon-gamma; Interleukin-10; Interleukin-2; Interleukin-4; Mice; Mice, Inbred BALB C; Phenols; Plant Extracts; Rhodiola; Spleen; Th1 Cells; Th2 Cells; Toxicity Tests, Acute; Toxicity Tests, Subacute | 2011 |
[Effects of salidroside on proliferation, apoptosis, phagocytosis, ROS and NO production of murine peritoneal macrophages in vitro].
Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Immunologic; Female; Glucosides; Interferon-gamma; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; Phagocytosis; Phenols; Reactive Oxygen Species | 2011 |
Simultaneous quantification of polyherbal formulations containing Rhodiola rosea L. and Eleutherococcus senticosus Maxim. using rapid resolution liquid chromatography (RRLC).
Topics: Calibration; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography; Chromatography, Liquid; Disaccharides; Eleutherococcus; Glucosides; Lignans; Phenols; Phenylethyl Alcohol; Phenylpropionates; Plant Extracts; Plant Preparations; Quality Control; Reproducibility of Results; Resins, Plant; Rhodiola | 2011 |
Characterization of glycosyltransferases responsible for salidroside biosynthesis in Rhodiola sachalinensis.
Topics: Acetates; Cyclopentanes; Glucosides; Glycosyltransferases; Oxylipins; Phenols; Phylogeny; Plant Roots; Plants, Genetically Modified; Recombinant Proteins; Rhodiola | 2011 |
Neuroprotection against cobalt chloride-induced cell apoptosis of primary cultured cortical neurons by salidroside.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Culture Techniques; Cell Nucleus; Cell Survival; Cells, Cultured; Cerebral Cortex; Cobalt; Drug Evaluation, Preclinical; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Neurons; Neuroprotective Agents; NF-kappa B; Phenols; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species | 2011 |
Salidroside attenuates hydrogen peroxide-induced cell damage through a cAMP-dependent pathway.
Topics: Animals; Cell Line; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Glucosides; Hydrogen Peroxide; Phenols | 2011 |
[Salidroside inhibits clinorotation-induced apoptosis in pulmonary microvascular endothelial cells].
Topics: Apoptosis; Caspase 3; Cell Line; Endothelial Cells; Endothelium, Vascular; Glucosides; Humans; Lung; Phenols; Signal Transduction; Weightlessness | 2011 |
Rhodiola rosea extracts and salidroside decrease the growth of bladder cancer cell lines via inhibition of the mTOR pathway and induction of autophagy.
Topics: Adaptor Proteins, Signal Transducing; Animals; Autophagy; Cell Line; Cell Proliferation; Epithelial Cells; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Mice; Phenols; Phosphorylation; Plant Extracts; Rhodiola; Signal Transduction; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins; Urinary Bladder Neoplasms | 2012 |
A tyrosine decarboxylase catalyzes the initial reaction of the salidroside biosynthesis pathway in Rhodiola sachalinensis.
Topics: Amino Acid Sequence; Biosynthetic Pathways; Cloning, Molecular; DNA, Antisense; DNA, Complementary; DNA, Plant; Glucosides; Molecular Sequence Data; Phenols; Phenylethyl Alcohol; Plants, Genetically Modified; Rhodiola; Sequence Analysis, DNA; Tyrosine Decarboxylase | 2011 |
[Study on the chemical constituents of Phlomis younghusbandii].
Topics: Flavones; Glucosides; Iridoids; Magnetic Resonance Spectroscopy; Molecular Structure; Phenols; Phlomis; Plant Roots; Plants, Medicinal; Pyrans | 2010 |
Salidroside protects against hydrogen peroxide-induced injury in cardiac H9c2 cells via PI3K-Akt dependent pathway.
Topics: Androstadienes; Animals; Antioxidants; Apoptosis; Cell Line; Cell Survival; Cytoprotection; Flow Cytometry; Gene Expression; Glucosides; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Myocytes, Cardiac; Oxidative Stress; Phenols; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Polymerase Chain Reaction; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Wortmannin | 2011 |
Rapid resolution liquid chromatography (RRLC) analysis for quality control of Rhodiola rosea roots and commercial standardized products.
Topics: Chromatography, High Pressure Liquid; Disaccharides; Glucosides; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Roots; Quality Control; Reference Standards; Resins, Plant; Rhodiola | 2011 |
Adjuvant effects of salidroside from Rhodiola rosea L. on the immune responses to ovalbumin in mice.
Topics: Adjuvants, Immunologic; Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Cytokines; Glucosides; Immunity, Cellular; Immunity, Humoral; Immunization; Immunoglobulin G; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Phenols; Rhodiola | 2011 |
The golden root, Rhodiola rosea, prolongs lifespan but decreases oxidative stress resistance in yeast Saccharomyces cerevisiae.
Topics: Adaptation, Physiological; Catalase; Colony Count, Microbial; Culture Media; Enzyme Activation; Enzyme Assays; Glucosides; Hydrogen Peroxide; Microbial Viability; Oxidative Stress; Phenols; Plant Extracts; Plant Roots; Rhodiola; Saccharomyces cerevisiae; Superoxide Dismutase; Time Factors; Water | 2011 |
Synthesis and biological evaluation of two salidroside analogues in the PC12 cell model exposed to hypoglycemia and serum limitation.
Topics: Animals; Apoptosis; Glucosides; Hypoglycemia; PC12 Cells; Phenols; Rats; Rhodiola; Serum | 2011 |
Salidroside inhibits migration and invasion of human fibrosarcoma HT1080 cells.
Topics: Antineoplastic Agents, Phytogenic; Cadherins; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Activation; Fibrosarcoma; Glucosides; Humans; Integrin beta1; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Phenols; Phosphorylation; Protease Inhibitors; Reactive Oxygen Species; Rhodiola | 2012 |
Salidroside attenuates LPS-induced pro-inflammatory cytokine responses and improves survival in murine endotoxemia.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cytokines; Down-Regulation; Endotoxemia; Glucosides; Inflammation; Lipopolysaccharides; Macrophages; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; Phenols; Treatment Outcome | 2011 |
[Study on preparation of salidroside and polysaccharide in Rhodiola crenulata].
Topics: Chemical Precipitation; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Ethanol; Glucosides; Phenols; Plants, Medicinal; Polysaccharides; Rhodiola; Technology, Pharmaceutical; Time Factors; Water | 2011 |
Rhodiola rosea extract protects human cortical neurons against glutamate and hydrogen peroxide-induced cell death through reduction in the accumulation of intracellular calcium.
Topics: Antioxidants; Calcium; Cell Death; Cell Line, Tumor; Cell Membrane; Cell Survival; Glucosides; Glutamic Acid; Homeostasis; Humans; Hydrogen Peroxide; Neurons; Neuroprotective Agents; Oxidative Stress; Phenols; Plant Extracts; Rhizome; Rhodiola | 2012 |
Neuroprotective effects of Salidroside and its analogue tyrosol galactoside against focal cerebral ischemia in vivo and H2O2-induced neurotoxicity in vitro.
Topics: Animals; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Brain Ischemia; Cell Survival; Cerebral Cortex; Disease Models, Animal; Drug Administration Schedule; Galactosides; Glucosides; Hydrogen Peroxide; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Oxidants; Phenols; Phenylethyl Alcohol; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury | 2012 |
Protective effect of salidroside from Rhodiolae Radix on diabetes-induced oxidative stress in mice.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Fasting; Glucosides; Insulin; Kidney; Lipids; Liver; Male; Malondialdehyde; Mice; Oxidative Stress; Phenols; Protective Agents; Rhodiola | 2011 |
Protective effects of a Rhodiola crenulata extract and salidroside on hippocampal neurogenesis against streptozotocin-induced neural injury in the rat.
Topics: Animals; Catalase; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Free Radical Scavengers; Glucosides; Hippocampus; Injections; Male; Neural Stem Cells; Neurogenesis; Neurons; Neuroprotective Agents; Oxidative Stress; Phenols; Plant Extracts; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rhodiola; Streptozocin | 2012 |
Eradication of Propionibacterium acnes biofilms by plant extracts and putative identification of icariin, resveratrol and salidroside as active compounds.
Topics: Acne Vulgaris; Biofilms; Dolichos; Drug Resistance, Bacterial; Epimedium; Flavonoids; Fruit; Glucosides; Humans; Malus; Microbial Sensitivity Tests; Phenols; Plant Extracts; Plant Roots; Polygonum; Propionibacterium acnes; Resveratrol; Rhizome; Rhodiola; Sebaceous Glands; Seeds; Stilbenes | 2012 |
Salidroside stimulates the accumulation of HIF-1α protein resulted in the induction of EPO expression: a signaling via blocking the degradation pathway in kidney and liver cells.
Topics: Basic Helix-Loop-Helix Transcription Factors; Erythropoietin; Glucosides; HEK293 Cells; Hematinics; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney; Liver; Phenols; Signal Transduction | 2012 |
Rejuvenating activity of salidroside (SDS): dietary intake of SDS enhances the immune response of aged rats.
Topics: Aging; Animals; Cell Proliferation; Dietary Supplements; Dose-Response Relationship, Drug; Glucosides; Immunity, Cellular; Male; Phenols; Rats; Rejuvenation; Rhodiola; Spleen; T-Lymphocytes | 2013 |
[Effect of salidroside on rat bone marrow mesenchymal stem cells differentiation into cholinergic nerve cells].
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Cholinergic Neurons; Glucosides; Mesenchymal Stem Cells; Phenols; Rats; Rats, Wistar | 2012 |
Salidroside stimulates DNA repair enzyme Parp-1 activity in mouse HSC maintenance.
Topics: Animals; Antioxidants; Cell Cycle; DNA; DNA Breaks, Double-Stranded; DNA Repair; Drug Evaluation, Preclinical; Fanconi Anemia Complementation Group A Protein; Fanconi Anemia Complementation Group C Protein; Glucosides; Hematopoietic Stem Cells; Hydrogen Peroxide; Mice; Mice, Inbred C57BL; Oxidants; Oxidative Stress; Phenols; Plants, Medicinal; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Rhodiola | 2012 |
Salidroside protects human erythrocytes against hydrogen peroxide-induced apoptosis.
Topics: Antioxidants; Apoptosis; Calcium; Dose-Response Relationship, Drug; Erythrocytes; Glucosides; Humans; Hydrogen Peroxide; Molecular Structure; Oxidative Stress; Phenols; Rhodiola | 2012 |
[Influence of salidroside from Rhodiola Sachalinensis A. Bor on some related indexes of free radical and energy metabolism after exercise in mice].
Topics: Animals; Energy Metabolism; Free Radicals; Glucosides; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Phenols; Physical Conditioning, Animal; Rhodiola | 2012 |
[Purification of salidroside in Rhodiola crenulata with macroporous resin].
Topics: Adsorption; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Phenols; Plants, Medicinal; Resins, Synthetic; Rhodiola; Solvents; Technology, Pharmaceutical | 2011 |
Simultaneous determination of salidroside and its aglycone metabolite p-tyrosol in rat plasma by liquid chromatography-tandem mass spectrometry.
Topics: Animals; Chromatography, Liquid; Glucosides; Male; Phenols; Phenylethyl Alcohol; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2012 |
Salidroside protects PC12 cells from MPP⁺-induced apoptosis via activation of the PI3K/Akt pathway.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Blotting, Western; Enzyme Activation; Flow Cytometry; Glucosides; L-Lactate Dehydrogenase; PC12 Cells; Phenols; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats | 2012 |
Salidroside and tyrosol from Rhodiola protect H9c2 cells from ischemia/reperfusion-induced apoptosis.
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Cell Line; Cytochromes c; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glucosides; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phenols; Phenylethyl Alcohol; Phosphorylation; Rats; Rhodiola | 2012 |
Protective effects of salidroside from Rhodiola rosea on LPS-induced acute lung injury in mice.
Topics: Acute Lung Injury; Animals; Cytokines; Disease Models, Animal; Glucosides; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Phenols; Rhodiola | 2012 |
Bioactivity-guided Isolation of antiosteoporotic compounds from Ligustrum lucidum.
Topics: Alkaline Phosphatase; Animals; Antioxidants; Bone Density Conservation Agents; Estrogens; Fruit; Glucosides; HeLa Cells; Humans; Ligustrum; Osteoblasts; Osteoporosis; Phenols; Phytotherapy; Plant Extracts; Pyrans; Rats; Receptors, Estrogen | 2013 |
Salidroside attenuates inflammatory responses by suppressing nuclear factor-κB and mitogen activated protein kinases activation in lipopolysaccharide-induced mastitis in mice.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Female; Glucosides; Lipopolysaccharides; Male; Mastitis; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-kappa B; Peroxidase; Phenols | 2013 |
Effects of salidroside on exhaustive exercise‑induced oxidative stress in rats.
Topics: Animals; Antioxidants; Catalase; Glucosides; Glutathione Peroxidase; Glycogen; Liver; Male; Malondialdehyde; Oxidative Stress; Phenols; Plant Roots; Rats; Rats, Sprague-Dawley; Rhodiola; Superoxide Dismutase; Swimming | 2012 |
Extraction and isolation of the salidroside-type metabolite from zinc (Zn) and cadmium (Cd) hyperaccumulator Sedum alfredii Hance.
Topics: Biodegradation, Environmental; Biomass; Cadmium; Chromatography, High Pressure Liquid; Glucosides; Hot Temperature; Phenols; Sedum; Soil Pollutants; Zinc | 2012 |
Salidroside improves behavioral and histological outcomes and reduces apoptosis via PI3K/Akt signaling after experimental traumatic brain injury.
Topics: Antioxidants; Apoptosis; Brain Edema; Brain Injuries; Cells, Cultured; Cerebral Cortex; Chromones; Dose-Response Relationship, Drug; Glucosides; Hippocampus; Injections, Intraperitoneal; Mitochondria; Morpholines; Motor Activity; Neurons; Neuroprotective Agents; Organ Specificity; Phenols; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Rotarod Performance Test; Signal Transduction; Stress, Physiological | 2012 |
Differential responses to UVB irradiation in human keratinocytes and epidermoid carcinoma cells.
Topics: Antioxidants; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Keratinocytes; Phenols; Ultraviolet Rays | 2012 |
[Study on effect and mechanism of salidroside on cognitive ability of Abeta1-40 -induced Alzheimer's disease model rats].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Disease Models, Animal; Glucosides; Male; Maze Learning; NF-kappa B; Nitric Oxide; Phenols; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Superoxide Dismutase | 2012 |
Effect of provenance, plant part and processing on extract profiles from cultivated European Rhodiola rosea L. for medicinal use.
Topics: Chromatography, High Pressure Liquid; Disaccharides; Glucosides; Magnetic Resonance Spectroscopy; Phenols; Rhodiola | 2013 |
Effects of salidroside pretreatment on expression of tumor necrosis factor-alpha and permeability of blood brain barrier in rat model of focal cerebralischemia-reperfusion injury.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Evans Blue; Gene Expression; Glucosides; Male; Phenols; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2013 |
Salidroside promotes peripheral nerve regeneration following crush injury to the sciatic nerve in rats.
Topics: Animal Diseases; Animals; Evoked Potentials, Motor; Glucosides; Locomotion; Male; Microscopy, Electron, Transmission; Muscle, Skeletal; Nerve Crush; Nerve Regeneration; Peripheral Nerves; Phenols; Rats; Rats, Sprague-Dawley; Recovery of Function; Sciatic Neuropathy; Stilbamidines | 2013 |
[Inhibitory effects of Rhodiola plants and their oligomeric proanthocyanidins on tyrosinase and Abeta42 aggregation].
Topics: Amyloid beta-Peptides; Drugs, Chinese Herbal; Glucosides; Monophenol Monooxygenase; Peptide Fragments; Phenols; Plant Roots; Plants, Medicinal; Proanthocyanidins; Rhodiola | 2012 |
A pH-responsive nano-carrier with mesoporous silica nanoparticles cores and poly(acrylic acid) shell-layers: fabrication, characterization and properties for controlled release of salidroside.
Topics: Acrylic Resins; Cetrimonium; Cetrimonium Compounds; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Glucosides; Hydrogen-Ion Concentration; Nanoparticles; Phenols; Porosity; Silicon Dioxide | 2013 |
Salidroside attenuates beta amyloid-induced cognitive deficits via modulating oxidative stress and inflammatory mediators in rat hippocampus.
Topics: Acetylcholine; Acetylcholinesterase; Amyloid beta-Peptides; Animals; Cognition Disorders; Cyclooxygenase 2; Glucosides; Hippocampus; Inflammation Mediators; Male; Maze Learning; Microinjections; NADPH Oxidases; Neuroprotective Agents; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Peptide Fragments; Phenols; Rats; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2013 |
Salidroside attenuates myocardial ischemia-reperfusion injury via PI3K/Akt signaling pathway.
Topics: Animals; Apoptosis; Blotting, Western; Chromones; Glucosides; Male; Molecular Structure; Morpholines; Myocytes, Cardiac; Phenols; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rabbits; Reperfusion Injury | 2013 |
Protection by salidroside against bone loss via inhibition of oxidative stress and bone-resorbing mediators.
Topics: Adaptor Proteins, Signal Transducing; Alkaline Phosphatase; Animals; Bone and Bones; Bone Density Conservation Agents; Bone Resorption; Cell Survival; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Female; Glucosides; Humans; Interleukin-6; Membrane Proteins; Mice; Osteoblasts; Osteocalcin; Osteoclasts; Osteoporosis; Phenols; Plant Extracts; RANK Ligand; Reactive Oxygen Species; Rhodiola; Transcription, Genetic | 2013 |
Synthesis and protective effects of novel salidroside analogues on glucose and serum depletion induced apoptosis in PC12 cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Survival; Glucose; Glucosides; Neuroprotective Agents; PC12 Cells; Phenols; Proto-Oncogene Proteins c-bcl-2; Rats; Structure-Activity Relationship | 2013 |
Antioxidant effect of salidroside and its protective effect against furan-induced hepatocyte damage in mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Bilirubin; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Furans; Glucosides; Glutathione Transferase; Hepatocytes; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Oxidative Stress; Phenols; Reactive Oxygen Species; Thiobarbiturates; Transaminases | 2013 |
In vitro and in vivo safety evaluation of Acer tegmentosum.
Topics: Acer; Animals; Bone Marrow Cells; Cells, Cultured; CHO Cells; Chromosome Aberrations; Cricetinae; Cricetulus; Escherichia coli; Female; Glucosides; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Mutagenicity Tests; Phenols; Phenylethyl Alcohol; Plant Extracts; Rats; Rats, Sprague-Dawley | 2013 |
Salidroside protects against hydrogen peroxide-induced injury in HUVECs via the regulation of REDD1 and mTOR activation.
Topics: Antioxidants; Apoptosis; Enzyme Activation; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases; Transcription Factors | 2013 |
[Effects of four kinds of Chinese medicine monomer on growth of PANC-1 xenograft tumor and studying of molecular mechanism].
Topics: Animals; Benzylisoquinolines; Caspase 3; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drugs, Chinese Herbal; Flavonoids; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Male; Mice; Mice, Nude; Phenols; Random Allocation; RNA, Messenger; RNA, Neoplasm; Saponins; Steroids; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2013 |
Citrus aurantium and Rhodiola rosea in combination reduce visceral white adipose tissue and increase hypothalamic norepinephrine in a rat model of diet-induced obesity.
Topics: Adipose Tissue, White; Animals; Citrus; Diet, High-Fat; Disaccharides; Dopamine; Glucosides; Hypothalamus; Kaolin; Male; Monoamine Oxidase; Norepinephrine; Obesity; Phenols; Phytotherapy; Plant Extracts; Plant Roots; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Rhodiola; Synephrine; Weight Loss | 2013 |
Inhibitory effects of salidroside and paeonol on tyrosinase activity and melanin synthesis in mouse B16F10 melanoma cells and ultraviolet B-induced pigmentation in guinea pig skin.
Topics: Acetophenones; Animals; Cell Line, Tumor; Female; Glucosides; Guinea Pigs; Melanins; Melanocytes; Mice; Monophenol Monooxygenase; Phenols; Pigmentation; Pigmentation Disorders; Skin; Ultraviolet Rays | 2013 |
Salidroside reduces cold-induced mucin production by inhibiting TRPM8 activation.
Topics: Calcium; Cell Survival; Cold Temperature; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation; Glucosides; Hep G2 Cells; Humans; Membrane Potentials; Mucin 5AC; Mucins; Phenols; TRPM Cation Channels | 2013 |
[Salidroside protects cultured rat subventricular zone neural stem cells against hypoxia injury by inhibiting Bax, Bcl-2 and caspase-3 expressions].
Topics: Animals; bcl-2-Associated X Protein; Caspase 3; Cell Hypoxia; Cells, Cultured; Flow Cytometry; Glucosides; Neural Stem Cells; Phenols; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2013 |
Salidroside attenuates LPS-stimulated activation of THP-1 cell-derived macrophages through down-regulation of MAPK/NF-kB signaling pathways.
Topics: Cell Line; Down-Regulation; Glucosides; Humans; Lipopolysaccharides; Macrophages; Mitogen-Activated Protein Kinases; NF-kappa B; Phenols; Signal Transduction | 2013 |
[II. Immunomodulation for multiple myeloma].
Topics: Bone Marrow Transplantation; Glucosides; Humans; Immunomodulation; Lenalidomide; Multiple Myeloma; Phenols; Thalidomide | 2013 |
Salidroside inhibits endogenous hydrogen peroxide induced cytotoxicity of endothelial cells.
Topics: Antioxidants; Apoptosis; Cell Line; Cell Survival; Endothelial Cells; Glucosides; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Malondialdehyde; Oxidative Stress; Phenols; Proto-Oncogene Proteins c-bcl-2; Superoxide Dismutase | 2013 |
[Salidroside inhibits hypoxia-induced phenotypic modulation of corpus cavernosum smooth muscle cells in vitro].
Topics: Actins; Animals; Cell Hypoxia; Cells, Cultured; Glucosides; Male; Myocytes, Smooth Muscle; Osteopontin; Penis; Phenols; Rats; Rats, Sprague-Dawley | 2013 |
Pharmacokinetics, tissue distribution, and excretion of salidroside in rats.
Topics: Adipose Tissue; Administration, Oral; Animals; Female; Glucosides; Injections, Intravenous; Kidney; Male; Muscle, Skeletal; Ovary; Phenols; Plant Extracts; Rats, Wistar; Rhodiola; Testis; Tissue Distribution | 2013 |
Salidroside stimulates osteoblast differentiation through BMP signaling pathway.
Topics: Animals; Biomarkers; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cell Differentiation; Cell Line; Gene Expression Regulation; Glucosides; Mice; Osteoblasts; Ovariectomy; Phenols; Phosphorylation; Pluripotent Stem Cells; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction | 2013 |
Salidroside improves doxorubicin-induced cardiac dysfunction by suppression of excessive oxidative stress and cardiomyocyte apoptosis.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Cardiotonic Agents; Cell Line; Cell Size; Cell Survival; Clone Cells; Doxorubicin; Gene Expression Regulation, Enzymologic; Glucosides; Heart Ventricles; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Oxidative Stress; Oxidoreductases; Phenols; Random Allocation; Rats; Ventricular Dysfunction | 2013 |
Engineering salidroside biosynthetic pathway in hairy root cultures of Rhodiola crenulata based on metabolic characterization of tyrosine decarboxylase.
Topics: Flowers; Glucosides; Phenols; Plant Roots; Plants, Genetically Modified; Rhodiola; Tyrosine Decarboxylase | 2013 |
Inhibitory effects of salidroside on nitric oxide and prostaglandin E₂ production in lipopolysaccharide-stimulated RAW 264.7 macrophages.
Topics: Animals; Anti-Inflammatory Agents; Calcium; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Glucosides; Inflammation; Inflammation Mediators; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phenols; Phytotherapy; Plant Extracts; Rhodiola; Signal Transduction | 2013 |
[Salidroside via ERK1/2 and PI3K/AKT/mTOR signal pathway induces mouse bone marrow mesenchymal stem cells differentiation into neural cells].
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Chromones; Enzyme Inhibitors; Flavonoids; Glial Fibrillary Acidic Protein; Glucosides; MAP Kinase Signaling System; Mesenchymal Stem Cells; Mice; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Nestin; Neurons; Phenols; Phosphatidylinositol 3-Kinases; Phosphopyruvate Hydratase; Plants, Medicinal; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rhodiola; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases; Tubulin | 2013 |
Salidroside liposome formulation enhances the activity of dendritic cells and immune responses.
Topics: Adjuvants, Immunologic; Allergens; Animals; Antigen Presentation; Cell Proliferation; Delayed-Action Preparations; Dendritic Cells; Female; Glucosides; Immunoglobulin G; Interferon-gamma; Interleukin-2; Liposomes; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Ovalbumin; Phenols; Spleen | 2013 |
Synthesis and neuroprotective effects of the fluorine substituted salidroside analogues in the PC12 cell model exposed to hypoglycemia and serum limitation.
Topics: Animals; Apoptosis; Culture Media; Fluorine; Glucosides; Hypoglycemia; Models, Biological; Neuroprotective Agents; PC12 Cells; Phenols; Plant Roots; Rats; Rhodiola | 2013 |
Rhodiola rosea L. extract and its active compound salidroside antagonized both induction and reinstatement of nicotine place preference in mice.
Topics: Animals; Association Learning; Behavior, Animal; Conditioning, Operant; Dose-Response Relationship, Drug; Glucosides; Mice; Motor Activity; Nicotine; Phenols; Plant Extracts; Rhodiola | 2014 |
Binding to WGR domain by salidroside activates PARP1 and protects hematopoietic stem cells from oxidative stress.
Topics: Amino Acid Sequence; Animals; Enzyme Activation; Glucosides; Hematopoietic Stem Cells; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Oxidative Stress; Phenols; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rats; Sequence Homology, Amino Acid | 2014 |
Salidroside induces rat mesenchymal stem cells to differentiate into dopaminergic neurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cells, Cultured; Dopaminergic Neurons; Glucosides; Mesenchymal Stem Cells; Microtubule-Associated Proteins; Nerve Growth Factors; Neurotrophin 3; Phenols; Rats; RNA, Messenger; Up-Regulation | 2014 |
[Effect of salidroside on apoptosis of bone marrow mesenchymal stem cells induced by ara-C].
Topics: Apoptosis; Bone Marrow Cells; Cells, Cultured; Cytarabine; Glucosides; Humans; Mesenchymal Stem Cells; Phenols | 2013 |
Amphiphilic chitosan derivatives-based liposomes: synthesis, development, and properties as a carrier for sustained release of salidroside.
Topics: Chitosan; Cholesterol; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Glucosides; Hydrophobic and Hydrophilic Interactions; Liposomes; Particle Size; Phenols | 2014 |
[Further chemical investigation of leaves of Aquilaria Sinensis].
Topics: Glucosides; Glycosides; Phenols; Plant Extracts; Plant Leaves; Saponins; Thymelaeaceae | 2013 |
The protection of salidroside of the heart against acute exhaustive injury and molecular mechanism in rat.
Topics: Animals; Cardiotonic Agents; Cell Shape; Creatine Kinase, MB Form; Extracellular Signal-Regulated MAP Kinases; Glucosides; Heart Function Tests; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardium; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2013 |
Salidroside exerts angiogenic and cytoprotective effects on human bone marrow-derived endothelial progenitor cells via Akt/mTOR/p70S6K and MAPK signalling pathways.
Topics: Adult; Angiogenesis Inducing Agents; Bone Marrow Cells; Cells, Cultured; Cytoprotection; Endothelial Progenitor Cells; Glucosides; Humans; MAP Kinase Signaling System; Middle Aged; Phenols; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; TOR Serine-Threonine Kinases; Young Adult | 2014 |
An LC-MS/MS method for the determination of salidroside and its metabolite p-tyrosol in rat liver tissues.
Topics: Acetaminophen; Animals; Chromatography, Liquid; Dose-Response Relationship, Drug; Glucosides; Limit of Detection; Liver; Male; Phenols; Phenylethyl Alcohol; Rats, Wistar; Reference Standards; Reproducibility of Results; Rhodiola; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tissue Distribution | 2014 |
Development of lipid-shell and polymer core nanoparticles with water-soluble salidroside for anti-cancer therapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Compounding; Glucosides; Humans; Lipids; Microscopy, Electron, Transmission; Nanoparticles; Phenols; Polyethylene Glycols; Polyglactin 910; Polymers; Solubility; Solvents; Water | 2014 |
Three new lignan glycosides with IL-6 inhibitory activity from Akebia quinata.
Topics: Caffeic Acids; Cells, Cultured; Drugs, Chinese Herbal; Glucosides; Glycosides; Humans; Interleukin-6; Lignans; Magnoliopsida; Molecular Structure; Phenols; Phenylpropionates; Tumor Necrosis Factor-alpha | 2014 |
MADP, a salidroside analog, protects hippocampal neurons from glutamate induced apoptosis.
Topics: Acetylglucosamine; Animals; Apoptosis; bcl-2-Associated X Protein; Cell Survival; Cells, Cultured; Flow Cytometry; Glucosides; Glutamic Acid; Hippocampus; In Situ Nick-End Labeling; Mitogen-Activated Protein Kinases; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Phenols; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Signal Transduction | 2014 |
Sequential release of salidroside and paeonol from a nanosphere-hydrogel system inhibits ultraviolet B-induced melanogenesis in guinea pig skin.
Topics: Administration, Topical; Animals; Cell Survival; Cells, Cultured; Delayed-Action Preparations; Dermatologic Agents; Diffusion; Drug Combinations; Drugs, Chinese Herbal; Glucosides; Guinea Pigs; Hydrogels; Melanins; Melanocytes; Nanocapsules; Nanospheres; Neoplasms, Radiation-Induced; Phenols; Treatment Outcome; Ultraviolet Rays | 2014 |
Salidroside attenuates concanavalin A-induced hepatitis via modulating cytokines secretion and lymphocyte migration in mice.
Topics: Animals; Cell Movement; Concanavalin A; Cytokines; Flow Cytometry; Glucosides; Hepatitis; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Phenols | 2014 |
Protective effect of salidroside on cardiac apoptosis in mice with chronic intermittent hypoxia.
Topics: Animals; Apoptosis; Cardiotonic Agents; Chronic Disease; Glucosides; Heart; Hypoxia; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Phenols; Rhodiola | 2014 |
Salidroside blocks the proliferation of pulmonary artery smooth muscle cells induced by platelet‑derived growth factor‑BB.
Topics: Animals; Becaplermin; Cell Proliferation; Cells, Cultured; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p27; G1 Phase Cell Cycle Checkpoints; Glucosides; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Myocytes, Smooth Muscle; Phenols; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Pulmonary Artery; Rats; Rats, Sprague-Dawley; S Phase Cell Cycle Checkpoints; Signal Transduction | 2014 |
Salidroside stimulates mitochondrial biogenesis and protects against H₂O₂-induced endothelial dysfunction.
Topics: AMP-Activated Protein Kinases; Animals; Aorta; Cell Survival; Cells, Cultured; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Mitochondria; NF-kappa B; Nitric Oxide Synthase Type III; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phenols; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Rhodiola; Transcription Factors | 2014 |
[Inhibitory effect of salidroside on hypoxia-induced apoptosis of corpus cavernosum smooth muscle cells in rats].
Topics: Animals; Apoptosis; Caspase 3; Cell Hypoxia; Cells, Cultured; Glucosides; Humans; Male; Myocytes, Smooth Muscle; Penis; Phenols; Rats | 2014 |
Protective effects of salidroside in the MPTP/MPP(+)-induced model of Parkinson's disease through ROS-NO-related mitochondrion pathway.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Survival; Dose-Response Relationship, Drug; Glucosides; Male; Mice; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Parkinsonian Disorders; Phenols; Reactive Oxygen Species; Signal Transduction | 2015 |
Salidroside protects Caenorhabditis elegans neurons from polyglutamine-mediated toxicity by reducing oxidative stress.
Topics: Animals; Caenorhabditis elegans; Glucosides; Neurons; Oxidative Stress; Peptides; Phenols | 2014 |
[Salidroside attenuates high glucose-induced apoptosis in human umbilical vein endothelial cells via activating the Ca(2)+/CaM/CAMKIIδ/eNOS pathway].
Topics: Apoptosis; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calmodulin; Cell Survival; Cells, Cultured; Glucose; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Phenols; Phosphatidylinositol 3-Kinases; Signal Transduction | 2014 |
Salidroside induces neuronal differentiation of mouse mesenchymal stem cells through Notch and BMP signaling pathways.
Topics: Animals; Base Sequence; Bone Morphogenetic Proteins; Cell Differentiation; DNA Primers; Glucosides; Mesenchymal Stem Cells; Mice; Neurons; Phenols; Real-Time Polymerase Chain Reaction; Receptors, Notch | 2014 |
[Comparation of gastrointestinal absorption studies of specnuezhenide with salidroside in rats].
Topics: Animals; Chemistry, Pharmaceutical; Gastrointestinal Tract; Glucosides; Intestinal Absorption; Male; Phenols; Pyrans; Rats; Rats, Sprague-Dawley | 2014 |
Effects of Salidroside on cobalt chloride-induced hypoxia damage and mTOR signaling repression in PC12 cells.
Topics: Animals; Cell Culture Techniques; Cell Hypoxia; Cell Survival; Cobalt; Glucosides; Neurons; Neuroprotective Agents; PC12 Cells; Phenols; Rats; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases | 2014 |
[Chemical constituents from whole plants of Aconitum tanguticum (III)].
Topics: Aconitum; Benzyl Alcohols; Furaldehyde; Glucosides; Molecular Structure; Phenols; Plant Extracts; Spectrometry, Mass, Electrospray Ionization | 2014 |
The effect of synthetic salidroside on cytokines and airway inflammation of asthma induced by diisocyanate (TDI) in mice by regulating GATA3/T-bet.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Eosinophils; Female; GATA3 Transcription Factor; Glucosides; Mice; Mice, Inbred BALB C; Phenols; T-Box Domain Proteins; Toluene 2,4-Diisocyanate | 2015 |
Anti-asthma effects of synthetic salidroside through regulation of Th1/Th2 balance.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Female; Glucosides; Humans; Interferon-gamma; Interleukin-4; Mice; Mice, Inbred BALB C; Phenols; Th1 Cells; Th2 Cells | 2014 |
Salidroside inhibits oxygen glucose deprivation (OGD)/re-oxygenation-induced H9c2 cell necrosis through activating of Akt-Nrf2 signaling.
Topics: Animals; Chromones; Cyclophilins; Gene Expression Regulation; Glucose; Glucosides; Membrane Potential, Mitochondrial; Mitochondria; Morpholines; Myocytes, Cardiac; Necrosis; NF-E2-Related Factor 2; Oxygen; Peptidyl-Prolyl Isomerase F; Phenols; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53 | 2014 |
Antidepressant-like effects of salidroside on olfactory bulbectomy-induced pro-inflammatory cytokine production and hyperactivity of HPA axis in rats.
Topics: Animals; Antidepressive Agents; Base Sequence; Behavior, Animal; Corticosterone; DNA Primers; Glucosides; Hypothalamo-Hypophyseal System; Inflammation Mediators; Male; Olfactory Bulb; Phenols; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction | 2014 |
The metabolism of salidroside to its aglycone p-tyrosol in rats following the administration of salidroside.
Topics: Animals; Bile; Chromatography, Liquid; Feces; Glucosides; Kidney; Liver; Male; Myocardium; Phenols; Phenylethyl Alcohol; Rats, Wistar; Rhodiola; Tandem Mass Spectrometry; Tissue Distribution | 2014 |
[Effects of salidroside on proliferation of bone marrow mesenchymal stem cells].
Topics: Bone Marrow Cells; Cell Cycle; Cell Proliferation; Cells, Cultured; Glucosides; Humans; Mesenchymal Stem Cells; Phenols; Stem Cell Factor | 2014 |
The protective effects of Rhodiola crenulata extracts on Drosophila melanogaster gut immunity induced by bacteria and SDS toxicity.
Topics: Animals; Bacteria; Cell Death; Drosophila melanogaster; Epithelial Cells; Glucosides; Intestines; Phenols; Plant Extracts; Reactive Oxygen Species; Rhodiola; Sodium Dodecyl Sulfate; Tibet | 2014 |
Mechanism of action of Rhodiola, salidroside, tyrosol and triandrin in isolated neuroglial cells: an interactive pathway analysis of the downstream effects using RNA microarray data.
Topics: Cell Line; Gene Expression Profiling; Gene Expression Regulation; Glucosides; Humans; Neuroglia; Oligonucleotide Array Sequence Analysis; Phenols; Phenylethyl Alcohol; Plant Extracts; Rhodiola; Signal Transduction; Transcriptome | 2014 |
Production of salidroside in metabolically engineered Escherichia coli.
Topics: Escherichia coli; Glucose; Glucosides; Glycosyltransferases; Metabolic Engineering; Phenols; Rhodiola | 2014 |
Salidroside attenuates allergic airway inflammation through negative regulation of nuclear factor-kappa B and p38 mitogen-activated protein kinase.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Down-Regulation; Female; Gene Expression; Glucosides; Lung; Mice, Inbred BALB C; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenols; Phytotherapy | 2014 |
Genetic, epigenetic, and HPLC fingerprint differentiation between natural and ex situ populations of Rhodiola sachalinensis from Changbai Mountain, China.
Topics: China; Chromatography, High Pressure Liquid; Cluster Analysis; DNA Methylation; Epigenesis, Genetic; Genetic Variation; Genetics, Population; Glucosides; Microsatellite Repeats; Phenols; Polymorphism, Genetic; Rhodiola | 2014 |
Evaluation of transdermal salidroside delivery using niosomes via in vitro cellular uptake.
Topics: Administration, Cutaneous; Animals; Biological Transport; Cell Line; Cholesterol; Glucosides; Hexoses; Humans; In Vitro Techniques; Liposomes; Male; Mice, Nude; Phenols; Rats, Sprague-Dawley; Skin; Sodium Dodecyl Sulfate | 2015 |
Therapeutic Intervention of Learning and Memory Decays by Salidroside Stimulation of Neurogenesis in Aging.
Topics: Aging; Animals; Cell Count; Cell Differentiation; Cell Survival; Cyclic AMP Response Element-Binding Protein; Dentate Gyrus; Glucosides; Green Fluorescent Proteins; Learning; Male; Memory Disorders; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Neuronal Plasticity; Neurons; Phenols; Rats; Spatial Memory; Synapses; Synaptic Transmission | 2016 |
Salidroside ameliorates Cd-induced calcium overload and gap junction dysfunction in BRL 3A rat liver cells.
Topics: Animals; Blotting, Western; Cadmium; Calcium; Cell Line; Cell Proliferation; Gap Junctions; Glucosides; Microscopy, Confocal; Phenols; Rats | 2015 |
An UPLC-MS-based metabolomics investigation on the anti-fatigue effect of salidroside in mice.
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Fatigue; Glucosides; Male; Metabolomics; Mice, Inbred Strains; Multivariate Analysis; Phenols; Principal Component Analysis; Rats; Rhodiola; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swimming | 2015 |
Salidroside protects against premature senescence induced by ultraviolet B irradiation in human dermal fibroblasts.
Topics: Cells, Cultured; Cellular Senescence; Glucosides; Humans; Inflammation Mediators; Matrix Metalloproteinase 1; Oxidative Stress; Phenols; Skin; Ultraviolet Rays | 2015 |
Salidroside alleviates paraquat-induced rat acute lung injury by repressing TGF-β1 expression.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Glucosides; Herbicides; Immunohistochemistry; Lung; Male; Paraquat; Phenols; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Transforming Growth Factor beta1 | 2014 |
Salidroside rescued mice from experimental sepsis through anti-inflammatory and anti-apoptosis effects.
Topics: Acute Lung Injury; Animals; Apoptosis; Cytokines; Drug Evaluation, Preclinical; Glucosides; Inflammation; Male; Mice, Inbred C57BL; Phenols; Phytotherapy; Plant Extracts; Random Allocation; Rhodiola; Sepsis; Spleen; Thymus Gland | 2015 |
Effects of Salidroside on Myocardial Injury In Vivo In Vitro via Regulation of Nox/NF-κB/AP1 Pathway.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Glucosides; Male; Membrane Glycoproteins; Myocardial Reperfusion Injury; NADPH Oxidase 2; NADPH Oxidases; NF-kappa B; Phenols; Rats; Rats, Wistar; Signal Transduction; Transcription Factor AP-1; Treatment Outcome | 2015 |
Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway.
Topics: Adipose Tissue; AMP-Activated Protein Kinases; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Glucosides; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hepatocytes; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Male; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Oxygen Consumption; Pancreas; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt | 2015 |
Anticancer effect of salidroside on colon cancer through inhibiting JAK2/STAT3 signaling pathway.
Topics: Antineoplastic Agents; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Colonic Neoplasms; Flow Cytometry; Glucosides; Humans; Janus Kinase 2; Phenols; Signal Transduction; STAT3 Transcription Factor | 2015 |
Diversity and antioxidant activity of culturable endophytic fungi from alpine plants of Rhodiola crenulata, R. angusta, and R. sachalinensis.
Topics: Antioxidants; Biodiversity; Fungi; Glucosides; Phenols; Rhodiola | 2015 |
Salidroside attenuates chronic hypoxia-induced pulmonary hypertension via adenosine A2a receptor related mitochondria-dependent apoptosis pathway.
Topics: Animals; Apoptosis; Disease Models, Animal; Gene Expression; Glucosides; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Lung; Male; Mice; Mitochondria; Myocytes, Smooth Muscle; Phenols; Pulmonary Artery; Receptor, Adenosine A2A; RNA, Messenger; Signal Transduction; Vascular Remodeling | 2015 |
[Effect of methyl jasmonate on salidroside and polysaccharide accumulation in Rhodiola sachalinensis callus].
Topics: Acetates; Biomass; Bioreactors; Cyclopentanes; Glucosides; Oxylipins; Peroxidase; Phenols; Polysaccharides; Rhodiola; Superoxide Dismutase | 2014 |
Salidroside inhibits the growth of human breast cancer in vitro and in vivo.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Female; G1 Phase; Glucosides; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Oxidative Stress; Phenols; Reactive Oxygen Species; Resting Phase, Cell Cycle | 2015 |
Salidroside prevents cognitive impairment induced by chronic cerebral hypoperfusion in rats.
Topics: Animals; Brain Ischemia; Brain Waves; Carotid Arteries; Carotid Stenosis; Cerebrovascular Circulation; Cognition Disorders; Dementia, Vascular; Disease Models, Animal; Glucosides; Hippocampus; Male; Maze Learning; Phenols; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rhodiola | 2015 |
Protective effect of salidroside on contrast-induced nephropathy in comparison with N-acetylcysteine and its underlying mechanism.
Topics: Acetylcysteine; Animals; Contrast Media; Cytoprotection; Glucosides; Kidney; Kidney Diseases; Oxidative Stress; Phenols; Rats; Rats, Wistar; Signal Transduction | 2015 |
The cardiovascular effects of salidroside in the Goto-Kakizaki diabetic rat model.
Topics: Animals; Aorta; Blood Pressure; Cardiotonic Agents; Cardiovascular Diseases; Cardiovascular System; Diabetes Mellitus, Type 2; Endothelium, Vascular; Glucose Intolerance; Glucosides; Guanylate Cyclase; Heart Rate; Hyperglycemia; Hypertension; Male; Myocytes, Smooth Muscle; Nitric Oxide Synthase Type III; Phenols; Rats; Rats, Inbred WKY; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilation | 2015 |
[Protective effect of Salidroside on oxidative damage to human lens epithelial cells].
Topics: Apoptosis; Caspase 3; Cell Survival; Cells, Cultured; Epithelial Cells; Flow Cytometry; Glucosides; Humans; Hydrogen Peroxide; Oxidants; Phenols | 2015 |
Salidroside-Mediated Neuroprotection is Associated with Induction of Early Growth Response Genes (Egrs) Across a Wide Therapeutic Window.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Brain; Brain Ischemia; Caspase 3; Disease Models, Animal; Dose-Response Relationship, Drug; Early Growth Response Transcription Factors; Glucosides; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; PC12 Cells; Phenols; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke; Time Factors | 2015 |
Salidroside protects retinal endothelial cells against hydrogen peroxide-induced injury via modulating oxidative status and apoptosis.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Endothelial Cells; Gene Expression Regulation; Glucosides; Humans; Hydrogen Peroxide; Medicine, Chinese Traditional; Oxidative Stress; Phenols; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Retina; Signal Transduction; Superoxide Dismutase; Wounds and Injuries | 2015 |
Rhodiola crenulata extract suppresses hepatic gluconeogenesis via activation of the AMPK pathway.
Topics: AMP-Activated Protein Kinases; Animals; Blood Glucose; Gluconeogenesis; Glucose; Glucosides; Hep G2 Cells; Humans; Liver; Male; Phenols; Phosphorylation; Plant Extracts; Plant Roots; Protein Kinase Inhibitors; Rats, Sprague-Dawley; Rhodiola; Signal Transduction | 2015 |
[Wnt/β-catenin signal pathway mediated Salidroside induced directional differentiation from mouse mesenchymal stem cells to nerve cells].
Topics: Animals; beta Catenin; Cell Differentiation; Glucosides; Glycogen Synthase Kinase 3; Lipoproteins, LDL; Low Density Lipoprotein Receptor-Related Protein-6; Mesenchymal Stem Cells; Mice; Neurons; Phenols; Phosphopyruvate Hydratase; RNA, Messenger; Signal Transduction; Wnt Signaling Pathway | 2015 |
Effects of Two Different Rhodiola rosea Extracts on Primary Human Visceral Adipocytes.
Topics: Adipocytes; Adipogenesis; Apoptosis; Cell Differentiation; Cell Survival; Cells, Cultured; Disaccharides; Fatty Acid-Binding Proteins; Fibroblast Growth Factor 2; GATA3 Transcription Factor; Gene Expression; Glucose Transporter Type 4; Glucosides; Glycerol; Humans; Intra-Abdominal Fat; Lipid Metabolism; Lipolysis; Phenols; Plant Extracts; PPAR gamma; Proto-Oncogene Proteins; Rhodiola; Wnt Proteins; Wnt3A Protein | 2015 |
miR-103 Regulates Oxidative Stress by Targeting the BCL2/Adenovirus E1B 19 kDa Interacting Protein 3 in HUVECs.
Topics: 3' Untranslated Regions; Apoptosis; Base Sequence; Down-Regulation; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Membrane Proteins; MicroRNAs; Oxidative Stress; Phenols; Proto-Oncogene Proteins; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Rhodiola; RNA Interference; RNA, Small Interfering; Sequence Alignment; Up-Regulation | 2015 |
Salidroside Protects against Cadmium-Induced Hepatotoxicity in Rats via GJIC and MAPK Pathways.
Topics: Animals; Cadmium; Cell Communication; Cells, Cultured; Female; Gap Junctions; Glucosides; Hepatocytes; Liver; MAP Kinase Signaling System; Phenols; Protective Agents; Rats | 2015 |
Salidroside Mitigates Sepsis-Induced Myocarditis in Rats by Regulating IGF-1/PI3K/Akt/GSK-3β Signaling.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Glucosides; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Inflammation Mediators; Insulin-Like Growth Factor I; Lipopolysaccharides; Male; Myocarditis; Myocardium; Phenols; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Sepsis; Signal Transduction | 2015 |
The Protective Effects of Salidroside from Exhaustive Exercise-Induced Heart Injury by Enhancing the PGC-1 α -NRF1/NRF2 Pathway and Mitochondrial Respiratory Function in Rats.
Topics: Animals; Electron Transport Chain Complex Proteins; Gene Expression Regulation; Glucosides; Heart Injuries; Male; Mitochondria; Muscle, Skeletal; Myocardium; NF-E2-Related Factor 2; Nuclear Respiratory Factor 1; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phenols; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcription Factors | 2015 |
Insulin receptor A and Sirtuin 1 synergistically improve learning and spatial memory following chronic salidroside treatment during hypoxia.
Topics: AMP-Activated Protein Kinases; Animals; Blood-Brain Barrier; Cell Survival; Cyclic AMP Response Element-Binding Protein; DNA, Mitochondrial; Glucosides; Hippocampus; Hypoxia; Male; Maze Learning; Mitochondria; Neurodegenerative Diseases; Phenols; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Sirtuin 1; Spatial Memory | 2015 |
Salidroside improves endothelial function and alleviates atherosclerosis by activating a mitochondria-related AMPK/PI3K/Akt/eNOS pathway.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Atherosclerosis; Diet, High-Fat; Endothelial Cells; Glucosides; Male; Mice; Mitochondria; Nitric Oxide; Nitric Oxide Synthase Type III; Phenols; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction | 2015 |
Salidroside ameliorates cognitive impairment in a d-galactose-induced rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; bcl-2-Associated X Protein; Carrier Proteins; Caspase 9; Cell Cycle Proteins; Cognition Disorders; Cytokines; Disease Models, Animal; Down-Regulation; Escape Reaction; Galactose; Glucosides; Hippocampus; Male; Maze Learning; Phenols; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Time Factors; Up-Regulation | 2015 |
Protective activity of salidroside against ethanol-induced gastric ulcer via the MAPK/NF-κB pathway in vivo and in vitro.
Topics: Animals; Anti-Ulcer Agents; Arachidonate 5-Lipoxygenase; Cell Line; Cell Survival; Cyclooxygenase 2; Cytokines; Ethanol; Glucosides; Humans; Hydrogen Peroxide; Leukotriene B4; Male; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-kappa B; Phenols; Signal Transduction; Stomach; Stomach Ulcer | 2015 |
[Simultaneously preparation of grams of high purity tyrosol, crenulatin and salidroside from Rhodiola crenulata].
Topics: Chemical Fractionation; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Coumarins; Drugs, Chinese Herbal; Glucosides; Phenols; Phenylethyl Alcohol; Rhodiola | 2015 |
Salidroside attenuates lipopolysaccharide (LPS) induced serum cytokines and depressive-like behavior in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cytokines; Depression; Enzyme Activation; Glucosides; Lipopolysaccharides; Male; Membrane Glycoproteins; Mice, Inbred ICR; Neuroprotective Agents; NF-kappa B; Norepinephrine; Phenols; Protein-Tyrosine Kinases; Serotonin | 2015 |
Phenylethanoid Glycoside Profiles and Antioxidant Activities of Osmanthus fragrans Lour. Flowers by UPLC/PDA/MS and Simulated Digestion Model.
Topics: Antioxidants; Caffeic Acids; Chlorogenic Acid; Digestion; Flowers; Glucosides; Glycosides; Models, Biological; Molecular Structure; Phenols; Phenylethyl Alcohol | 2016 |
The cardioprotective effect of salidroside against myocardial ischemia reperfusion injury in rats by inhibiting apoptosis and inflammation.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Glucosides; Humans; Interleukin-1beta; Interleukin-6; Male; Myocardial Reperfusion Injury; Phenols; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2015 |
[Protective effect of salidroside against high altitude hypoxia-induced brain injury in rats].
Topics: Altitude Sickness; Animals; Apoptosis; Cytoprotection; Dentate Gyrus; Extracellular Signal-Regulated MAP Kinases; Glucosides; Hypoxia, Brain; Male; Phenols; Rats; Rats, Sprague-Dawley; Respiration; rhoA GTP-Binding Protein | 2015 |
SILAC-based proteomic analysis reveals that salidroside antagonizes cobalt chloride-induced hypoxic effects by restoring the tricarboxylic acid cycle in cardiomyocytes.
Topics: Adenosine Triphosphate; Apoptosis; Calcium; Caspase 3; Caspase 9; Cell Line; Chromatography, Liquid; Citric Acid Cycle; Cobalt; Computational Biology; Glucosides; Hypoxia; Membrane Potentials; Myocytes, Cardiac; Oxygen; Phenols; Plant Extracts; Proteome; Proteomics; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Rhodiola; Tandem Mass Spectrometry; Tricarboxylic Acids | 2016 |
Metabolite Profile of Salidroside in Rats by Ultraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry and High-Performance Liquid Chromatography Coupled with Quadrupole-Linear Ion Trap Mass Spectrometry.
Topics: Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Male; Metabolic Networks and Pathways; Molecular Structure; Phenols; Rats; Rats, Wistar; Rhodiola; Tandem Mass Spectrometry | 2015 |
Metabolic profile of salidroside in rats using high-performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry.
Topics: Animals; Antioxidants; Bile; Chromatography, High Pressure Liquid; Cyclotrons; Feces; Fourier Analysis; Glucosides; Male; Mass Spectrometry; Metabolic Networks and Pathways; Metabolome; Phenols; Rats; Rats, Sprague-Dawley; Rhodiola | 2016 |
Suppressing Receptor-Interacting Protein 140: a New Sight for Salidroside to Treat Cerebral Ischemia.
Topics: Animals; bcl-2-Associated X Protein; Brain; Brain Edema; Brain Ischemia; Cell Line, Tumor; Cell Survival; Cytokines; Glucosides; Humans; Male; NF-kappa B; Nuclear Receptor Co-Repressor 1; Phenols; Rats, Sprague-Dawley; Signal Transduction | 2016 |
Salidroside protects against bleomycin-induced pulmonary fibrosis: activation of Nrf2-antioxidant signaling, and inhibition of NF-κB and TGF-β1/Smad-2/-3 pathways.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bleomycin; Cell Line; Glucosides; Humans; Lung; NF-E2-Related Factor 2; NF-kappa B; Phenols; Pulmonary Fibrosis; Rats, Sprague-Dawley; Rhodiola; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1 | 2016 |
The authenticity and quality of Rhodiola rosea products.
Topics: Chromatography, Thin Layer; Curcuma; Dietary Supplements; Drug Contamination; Drugs, Chinese Herbal; Glucosides; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metabolomics; Phenols; Plant Extracts; Quality Control; Reference Standards; Rhodiola | 2016 |
A novel mechanism of action for salidroside to alleviate diabetic albuminuria: effects on albumin transcytosis across glomerular endothelial cells.
Topics: Albumins; Albuminuria; AMP-Activated Protein Kinases; Animals; Caveolin 1; Creatinine; Diabetic Nephropathies; Endothelial Cells; Glucose; Glucosides; In Vitro Techniques; Kidney Glomerulus; Mesangial Cells; Mice; Phenols; Phosphorylation; src-Family Kinases; Transcytosis | 2016 |
Salidroside ameliorates arthritis-induced brain cognition deficits by regulating Rho/ROCK/NF-κB pathway.
Topics: Animals; Arthritis; Brain Chemistry; Cognition Disorders; Collagen; Freund's Adjuvant; Glucosides; Hippocampus; Interleukin-1beta; Interleukin-6; Maze Learning; NF-kappa B; Phenols; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction; Tumor Necrosis Factor-alpha | 2016 |
Salidroside Protects Against 6-Hydroxydopamine-Induced Cytotoxicity by Attenuating ER Stress.
Topics: Adrenergic Agents; Animals; Apoptosis; Blotting, Western; Cell Line; Cell Survival; Dopaminergic Neurons; Endoplasmic Reticulum Stress; Glucosides; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Phenols; Rats; Rats, Sprague-Dawley | 2016 |
Salidroside suppresses inflammation in a D-galactose-induced rat model of Alzheimer's disease via SIRT1/NF-κB pathway.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Brain; Cognition; Disease Models, Animal; Galactose; Glucosides; Inflammation; Male; Memory; NF-kappa B; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1 | 2016 |
Salidroside protects against kainic acid-induced status epilepticus via suppressing oxidative stress.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Forkhead Transcription Factors; Glucosides; Glutathione; Hippocampus; Kainic Acid; Male; Malondialdehyde; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroprotective Agents; Oxidative Stress; Phenols; Seizures; Sirtuin 1; Status Epilepticus; Superoxide Dismutase | 2016 |
Salidroside-regulated lipid metabolism with down-regulation of miR-370 in type 2 diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Down-Regulation; Glucosides; Insulin; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Phenols | 2016 |
[Effects of Salidroside on Tic Behavior of Tourette Syndrome Model Rats].
Topics: Animals; Corpus Striatum; Dopamine; Drugs, Chinese Herbal; Glucosides; Haloperidol; Phenols; Rats; Serotonin; Stereotyped Behavior; Tics; Tourette Syndrome | 2016 |
Salidroside, a Bioactive Compound of Rhodiola Rosea, Ameliorates Memory and Emotional Behavior in Adult Mice.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Conditioning, Psychological; Depressive Disorder; Disease Models, Animal; Drug Evaluation, Preclinical; Exploratory Behavior; Fear; Female; Freezing Reaction, Cataleptic; Glucosides; Male; Maze Learning; Memory; Mice, Inbred C57BL; Motor Activity; Nootropic Agents; Phenols; Phytotherapy; Plant Extracts; Rhodiola | 2016 |
[Optimization of extraction technology for salidroside, tyrosol, crenulatin and gallic acid in Rhodiolae Crenulatae Radix et Rhizoma with orthogonal test].
Topics: Chemical Fractionation; Chemistry, Pharmaceutical; Coumarins; Drugs, Chinese Herbal; Gallic Acid; Glucosides; Phenols; Phenylethyl Alcohol; Rhizome; Rhodiola | 2015 |
Salidroside suppresses solar ultraviolet-induced skin inflammation by targeting cyclooxygenase-2.
Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Glucosides; Humans; Keratinocytes; Mice; Mice, Inbred BALB C; Phenols; Phosphorylation; Radiodermatitis; Skin; Sunlight | 2016 |
Quantitative Analysis of Salidroside and p-Tyrosol in the Traditional Tibetan Medicine Rhodiola crenulata by Fourier Transform Near-Infrared Spectroscopy.
Topics: Chromatography, High Pressure Liquid; Fourier Analysis; Glucosides; Limit of Detection; Medicine, Tibetan Traditional; Phenols; Phenylethyl Alcohol; Rhodiola; Spectroscopy, Near-Infrared | 2016 |
Salidroside alleviates oxidative stress in the liver with non- alcoholic steatohepatitis in rats.
Topics: Administration, Oral; Animals; Antioxidants; Cytochrome P-450 CYP2E1; Diet, High-Fat; Dose-Response Relationship, Drug; Enzyme Repression; Glucosides; Lipid Droplets; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Oxidoreductases; Phenols; Random Allocation; Rats, Sprague-Dawley; Up-Regulation | 2016 |
Salidroside attenuates inflammatory response via suppressing JAK2-STAT3 pathway activation and preventing STAT3 transfer into nucleus.
Topics: Active Transport, Cell Nucleus; Acute Lung Injury; Animals; Cell Nucleus; Cytokines; Glucosides; Immunosuppressive Agents; Inflammation; Inflammation Mediators; Janus Kinase 2; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Phenols; RAW 264.7 Cells; Signal Transduction; STAT3 Transcription Factor | 2016 |
Potential of the Endophytic Fungus Phialocephala fortinii Rac56 Found in Rhodiola Plants to Produce Salidroside and p-Tyrosol.
Topics: Endophytes; Fermentation; Glucosides; Hydrogen-Ion Concentration; Phenols; Phenylethyl Alcohol; Phylogeny; Rhodiola; Saccharomycetales; Temperature | 2016 |
Neuroprotective effects of salidroside through PI3K/Akt pathway activation in Alzheimer's disease models.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Drosophila; Glucosides; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rhodiola; Signal Transduction | 2016 |
Salidroside improves glucose homeostasis in obese mice by repressing inflammation in white adipose tissues and improving leptin sensitivity in hypothalamus.
Topics: Adipose Tissue, White; Animals; Body Weight; Eating; Epididymis; Glucose-6-Phosphatase; Glucosides; Hyperglycemia; Hypothalamus; Inflammation; Leptin; Liver; Male; Mice; Mice, Obese; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phenols; Triglycerides | 2016 |
Cardioprotective effects of salidroside on myocardial ischemia-reperfusion injury in coronary artery occlusion-induced rats and Langendorff-perfused rat hearts.
Topics: Adenosine Triphosphate; Animals; Cardiotonic Agents; Coronary Occlusion; Energy Metabolism; Glucosides; Glycogen; In Vitro Techniques; Isolated Heart Preparation; Male; Myocardial Reperfusion Injury; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phenols; PPAR alpha; Random Allocation; Rats; Rats, Sprague-Dawley | 2016 |
Evolution of Vertebrate Phototransduction: Cascade Activation.
Topics: Animals; Biological Evolution; Evolution, Molecular; Eye; Fishes; Genome; Glucosides; GTP-Binding Protein alpha Subunits; High-Throughput Nucleotide Sequencing; Lampreys; Light Signal Transduction; Phenols; Phylogeny; Retinal Cone Photoreceptor Cells | 2016 |
Rhodioloside ameliorates depressive behavior via up-regulation of monoaminergic system activity and anti-inflammatory effect in olfactory bulbectomized rats.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Biogenic Monoamines; Depression; Disease Models, Animal; Glucosides; Interleukin-1beta; Interleukin-6; Male; NF-kappa B; Olfactory Bulb; Phenols; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Rhodiola; Signal Transduction | 2016 |
A new family-3 glycoside hydrolase from Penicillium oxalicum BL 3005 catalyzing tyrosol glucosylation to form salidroside.
Topics: Biocatalysis; Electrophoresis, Polyacrylamide Gel; Glucosides; Glycoside Hydrolases; Glycosylation; Molecular Weight; Penicillium; Phenols; Phenylethyl Alcohol | 2017 |
An Approach to Characterizing the Complicated Sequential Metabolism of Salidroside in Rats.
Topics: Animals; Chromatography, Liquid; Gastric Juice; Glucosides; Intestinal Mucosa; Male; Metabolomics; Phenols; Rats; Tandem Mass Spectrometry | 2016 |
Salidroside reduces renal cell carcinoma proliferation by inhibiting JAK2/STAT3 signaling.
Topics: Animals; Apoptosis; Carcinoma, Renal Cell; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Glucosides; Humans; Janus Kinase 2; Kidney Neoplasms; Male; Mice; Phenols; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays | 2016 |
Salidroside protects cortical neurons against glutamate-induced cytotoxicity by inhibiting autophagy.
Topics: Animals; Autophagy; Cell Survival; Cerebral Cortex; Glucosides; Glutamic Acid; Nerve Tissue Proteins; Neurons; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction | 2016 |
Salidroside Suppresses HUVECs Cell Injury Induced by Oxidative Stress through Activating the Nrf2 Signaling Pathway.
Topics: Catalase; Glucosides; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Malondialdehyde; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Phenols; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 2016 |
Protective effect of salidroside against bone loss via hypoxia-inducible factor-1α pathway-induced angiogenesis.
Topics: Alkaline Phosphatase; Angiogenesis Inducing Agents; Animals; Bone Density; Cell Hypoxia; Cell Line; Cobalt; Female; Glucosides; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Osteoblasts; Osteoporosis; Ovariectomy; Phenols; Protective Agents; Rats, Sprague-Dawley; Rats, Wistar; Signal Transduction | 2016 |
Salidroside exhibits anti-dengue virus activity by upregulating host innate immune factors.
Topics: Antiviral Agents; Cell Line; Cells, Cultured; Dengue Virus; Gene Expression Profiling; Glucosides; Humans; Immunologic Factors; Monocytes; Phenols; Rhodiola; Viral Proteins | 2016 |
Expression of Codon-Optimized Plant Glycosyltransferase UGT72B14 in Escherichia coli Enhances Salidroside Production.
Topics: Amino Acid Sequence; Catalysis; Codon; Escherichia coli; Gene Expression Regulation, Plant; Glucosides; Glycosyltransferases; Phenols; Rhodiola | 2016 |
Salidroside's Protection Against UVB-Mediated Oxidative Damage and Apoptosis Is Associated with the Upregulation of Nrf2 Expression.
Topics: Animals; Apoptosis; Cells, Cultured; Epidermal Cells; Epidermis; Glucosides; Guinea Pigs; Humans; Keratinocytes; NF-E2-Related Factor 2; Oxidative Stress; Phenols; Radiation Protection; Skin; Ultraviolet Rays; Up-Regulation | 2017 |
Salidroside as a Novel Protective Agent to Improve Red Blood Cell Cryopreservation.
Topics: Animals; Cryopreservation; Erythrocytes; Glucosides; Phenols; Sheep | 2016 |
Salidroside induces apoptosis and autophagy in human colorectal cancer cells through inhibition of PI3K/Akt/mTOR pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Beclin-1; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Glucosides; HT29 Cells; Humans; Microtubule-Associated Proteins; Phenols; Phosphatidylinositol 3-Kinases; Signal Transduction; TOR Serine-Threonine Kinases | 2016 |
Anti-inflammatory effect of salidroside on phorbol-12-myristate-13-acetate plus A23187-mediated inflammation in HMC-1 cells.
Topics: Anti-Inflammatory Agents; Calcimycin; Cell Line, Tumor; Cytokines; Gene Expression Regulation; Glucosides; Humans; Inflammation; Inflammation Mediators; Mitogen-Activated Protein Kinases; NF-kappa B; Phenols; Phorbol Esters; Signal Transduction | 2016 |
Comparative Study on the Protective Effects of Salidroside and Hypoxic Preconditioning for Attenuating Anoxia-Induced Apoptosis in Pheochromocytoma (PC12) Cells.
Topics: Animals; Apoptosis; Cell Hypoxia; Cell Survival; Glucosides; Hypoxia; Ischemic Preconditioning; Membrane Potential, Mitochondrial; Mitochondria; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Phenols; Rats; Reactive Oxygen Species | 2016 |
Salidroside protects against homocysteine-induced injury in human umbilical vein endothelial cells via the regulation of endoplasmic reticulum stress.
Topics: Cell Survival; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; eIF-2 Kinase; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Endoribonucleases; Glucosides; Heat-Shock Proteins; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; Phenols; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; Time Factors; Transcription Factor CHOP | 2017 |
Salidroside Regulates Inflammatory Response in Raw 264.7 Macrophages via TLR4/TAK1 and Ameliorates Inflammation in Alcohol Binge Drinking-Induced Liver Injury.
Topics: Animals; Binge Drinking; Cyclooxygenase 2; Glucosides; Lipopolysaccharides; Liver Diseases, Alcoholic; Male; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Phenols; RAW 264.7 Cells; Toll-Like Receptor 4 | 2016 |
Induction of autophagy by salidroside through the AMPK-mTOR pathway protects vascular endothelial cells from oxidative stress-induced apoptosis.
Topics: AMP-Activated Protein Kinases; Apoptosis; Autophagy; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Oxidative Stress; Phenols; Signal Transduction; TOR Serine-Threonine Kinases | 2017 |
Salidroside accelerates fracture healing through cell-autonomous and non-autonomous effects on osteoblasts.
Topics: Animals; Calcification, Physiologic; Cell Cycle; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Core Binding Factor Alpha 1 Subunit; Disease Models, Animal; Fracture Healing; Glucosides; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Osteoblasts; Osteogenesis; Phenols; Platelet Endothelial Cell Adhesion Molecule-1; Rats, Sprague-Dawley; Signal Transduction; Sp7 Transcription Factor; Transcription Factors; Transcriptional Activation; Vascular Endothelial Growth Factor A | 2017 |
Salidroside alleviates cigarette smoke-induced COPD in mice.
Topics: Animals; Dose-Response Relationship, Drug; Glucosides; Lung; Male; Mice; Mice, Inbred ICR; NF-kappa B; Phenols; Pulmonary Disease, Chronic Obstructive; Random Allocation; Smoking; Tumor Necrosis Factor-alpha | 2017 |
Salidroside promotes peripheral nerve regeneration based on tissue engineering strategy using Schwann cells and PLGA: in vitro and in vivo.
Topics: Animals; Cell Line; Cells, Cultured; Glucosides; Lactic Acid; Nerve Growth Factors; Nerve Regeneration; Neuroprotective Agents; Peripheral Nerve Injuries; Phenols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Schwann Cells; Sciatic Nerve; Tissue Engineering; Tissue Scaffolds | 2017 |
Protective effects of salidroside against isoflurane-induced cognitive impairment in rats.
Topics: Acetylcholine; Acetylcholinesterase; Anesthetics, Inhalation; Animals; Antioxidants; Choline O-Acetyltransferase; Cognitive Dysfunction; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucosides; Hippocampus; Isoflurane; Male; Phenols; Random Allocation; Rats; Rats, Sprague-Dawley | 2017 |
[Effects of salidroside on the secretion of inflammatory mediators induced by lipopolysaccharide in murine macrophage cell line J774.1].
Topics: Animals; Cell Line; Chemokine CCL2; Chemokine CXCL2; Enzyme-Linked Immunosorbent Assay; Glucosides; Inflammation; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Phenols; Signal Transduction; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2017 |
[Salidroside protects PC12 cells from H
Topics: Animals; Apoptosis; Caspase 3; Glucosides; Hydrogen Peroxide; MAP Kinase Signaling System; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Neuroprotective Agents; PC12 Cells; Phenols; Phosphorylation; Rats; Reactive Oxygen Species | 2016 |
[Salidroside improves pulmonary fibrosis by down-regulation of cathepsin B and NF-κBp65 in rats].
Topics: Animals; Cathepsin B; Down-Regulation; Glucosides; Lung; NF-kappa B; Oximetry; Oxygen; Phenols; Pulmonary Fibrosis; Pulmonary Gas Exchange; Pyridones; Rats; Rats, Sprague-Dawley | 2017 |
Inhibition of PHD3 by salidroside promotes neovascularization through cell-cell communications mediated by muscle-secreted angiogenic factors.
Topics: Angiogenesis Inducing Agents; Animals; Cell Communication; Cell Line; Disease Models, Animal; Endothelial Cells; Glucosides; Hindlimb; Humans; Injections, Intramuscular; Ischemia; Mice, Inbred BALB C; Muscle Cells; Neovascularization, Physiologic; Phenols; Procollagen-Proline Dioxygenase | 2017 |
Salidroside protects rat liver against ischemia/reperfusion injury by regulating the GSK-3β/Nrf2-dependent antioxidant response and mitochondrial permeability transition.
Topics: Animals; Antioxidants; Caspases; Cytochromes c; Cytoprotection; Enzyme Activation; Glucosides; Glycogen Synthase Kinase 3 beta; Liver; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; NF-E2-Related Factor 2; Phenols; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2017 |
Salidroside contributes to reducing blood pressure and alleviating cerebrovascular contractile activity in diabetic Goto-Kakizaki Rats by inhibition of L-type calcium channel in smooth muscle cells.
Topics: Animals; Blood Glucose; Blood Pressure; Calcium Channels, L-Type; Cells, Cultured; Cerebral Arteries; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Gene Expression Regulation; Glucosides; Hypoglycemic Agents; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenols; Rats, Inbred WKY; RNA, Messenger; Vasodilation | 2017 |
Salidroside attenuates colistin-induced neurotoxicity in RSC96 Schwann cells through PI3K/Akt pathway.
Topics: Animals; Apoptosis; Blotting, Western; Cell Line; Cell Survival; Colistin; Flow Cytometry; Fluorescent Antibody Technique; Glucosides; Neuroprotective Agents; Oncogene Protein v-akt; Phenols; Phosphatidylinositol 3-Kinase; Rats; Reactive Oxygen Species; Schwann Cells; Signal Transduction | 2017 |
Salidroside Inhibits Inflammation Through PI3K/Akt/HIF Signaling After Focal Cerebral Ischemia in Rats.
Topics: Animals; Anti-Inflammatory Agents; Brain Ischemia; Erythropoietin; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Reperfusion Injury; Signal Transduction | 2017 |
Salidroside Attenuates Ventilation Induced Lung Injury via SIRT1-Dependent Inhibition of NLRP3 Inflammasome.
Topics: Animals; Bronchoalveolar Lavage Fluid; Caspase 1; Cells, Cultured; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Glucosides; Inflammasomes; Interleukin-1beta; Lung; Male; Mice; Mice, Inbred ICR; NLR Family, Pyrin Domain-Containing 3 Protein; Phenols; RNA Interference; RNA, Small Interfering; Sirtuin 1; Stress, Mechanical; Up-Regulation; Ventilator-Induced Lung Injury | 2017 |
Salidroside Attenuates LPS-Induced Acute Lung Injury in Rats.
Topics: A549 Cells; Animals; Antioxidants; Caveolin 1; Endotoxemia; Glucosides; Humans; Lipopolysaccharides; Lung; Lung Injury; NF-kappa B; Phenols; Rats | 2017 |
Production of three phenylethanoids, tyrosol, hydroxytyrosol, and salidroside, using plant genes expressing in Escherichia coli.
Topics: Escherichia coli; Gene Expression Regulation, Enzymologic; Glucosides; Glycosyltransferases; Phenols; Phenylethyl Alcohol; Rhodiola | 2017 |
[Protective effect of synthetic salidroside on acute lung injury in rats].
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Dexamethasone; Glucosides; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Lung; Male; Malondialdehyde; Neutrophils; NF-kappa B; Peroxidase; Phenols; Phosphorylation; Random Allocation; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2017 |
Salidroside protects PC12 cells from Aβ1‑40‑induced cytotoxicity by regulating the nicotinamide phosphoribosyltransferase signaling pathway.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Glucosides; Neuroprotective Agents; Nicotinamide Phosphoribosyltransferase; PC12 Cells; Peptide Fragments; Phenols; Rats; Rhodiola; Signal Transduction | 2017 |
Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.
Topics: Animals; Anisomycin; Apoptosis; Autophagy; Cytokines; Enzyme Activators; Glucosides; Hepatocytes; Kidney Function Tests; Liver; Liver Function Tests; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Phenols; Phosphorylation; Protective Agents; Reperfusion Injury | 2017 |
Salidroside Ameliorates Diabetic Neuropathic Pain in Rats by Inhibiting Neuroinflammation.
Topics: Analgesics; Animals; Diabetic Neuropathies; Glucosides; HEK293 Cells; Humans; Interleukin-1beta; Nociception; Phenols; Rats; Rats, Zucker; Receptors, Purinergic P2X7; Sciatic Nerve; Spinal Cord; Tumor Necrosis Factor-alpha | 2017 |
Salidroside Reduces High-Glucose-Induced Podocyte Apoptosis and Oxidative Stress via Upregulating Heme Oxygenase-1 (HO-1) Expression.
Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Gene Expression; Glucose; Glucosides; Heme Oxygenase-1; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Podocytes; Reactive Oxygen Species; Transcriptional Activation; Up-Regulation | 2017 |
SIRT1 mediates salidroside-elicited protective effects against MPP
Topics: 1-Methyl-4-phenylpyridinium; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Glucosides; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phenols; Reactive Oxygen Species; RNA, Messenger; Sirtuin 1 | 2018 |
Degradation of phenylethanoid glycosides in Osmanthus fragrans Lour. flowers and its effect on anti-hypoxia activity.
Topics: Animals; Cell Differentiation; Cell Hypoxia; Cell Survival; Cobalt; Drug Stability; Flowers; Glucosides; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Light; Neurons; Oleaceae; PC12 Cells; Phenols; Plant Extracts; Protective Agents; Rats | 2017 |
Salidroside, a Chemopreventive Glycoside, Diminishes Cytotoxic Effect of Cisplatin in Vitro.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Comet Assay; DNA Damage; Drug Antagonism; Drug Synergism; Female; Glucosides; Hep G2 Cells; Hepatocytes; Humans; Ovarian Neoplasms; Phenols; Protective Agents; Reproducibility of Results; Signal Transduction | 2018 |
[Spectrum-effect relationship in antioxidant activity of Ligustri Lucidi Fructus based on DPPH, ABTS and FRAP assays].
Topics: Antioxidants; Drugs, Chinese Herbal; Fruit; Glucosides; Ligustrum; Medicine, Chinese Traditional; Phenols; Pyrans | 2016 |
Salidroside, a scavenger of ROS, enhances the radioprotective effect of Ex-RAD® via a p53-dependent apoptotic pathway.
Topics: Animals; Apoptosis; DNA Damage; Drug Synergism; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Mice; Phenols; Radiation-Protective Agents; Reactive Oxygen Species; Sulfonamides; Survival Rate; Tumor Suppressor Protein p53 | 2017 |
Salidroside suppressing LPS-induced myocardial injury by inhibiting ROS-mediated PI3K/Akt/mTOR pathway in vitro and in vivo.
Topics: Animals; Cardiotonic Agents; Catalase; Cell Line; Dexamethasone; Endotoxemia; Gene Expression Regulation; Glucosides; Glutathione; Glutathione Peroxidase; Hemodynamics; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Nitric Oxide Synthase Type II; Phenols; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2017 |
Endoplasmic Reticulum Stress and NF-[Formula: see text]B Pathway in Salidroside Mediated Neuroprotection: Potential of Salidroside in Neurodegenerative Diseases.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Endoplasmic Reticulum Stress; Glucosides; Inflammation Mediators; Mice; Microglia; Neurodegenerative Diseases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phenols; Phytotherapy; RNA, Messenger; Signal Transduction | 2017 |
Fungal endophyte-induced salidroside and tyrosol biosynthesis combined with signal cross-talk and the mechanism of enzyme gene expression in Rhodiola crenulata.
Topics: Ascomycota; Endophytes; Gene Expression Regulation, Enzymologic; Glucosides; Hydrogen Peroxide; Monoamine Oxidase; Nitric Oxide; Phenols; Phenylalanine Ammonia-Lyase; Phenylethyl Alcohol; Rhodiola; Salicylic Acid; Tyrosine Decarboxylase | 2017 |
Salidroside protects against foam cell formation and apoptosis, possibly via the MAPK and AKT signaling pathways.
Topics: Antioxidants; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member 1; Cell Differentiation; Extracellular Signal-Regulated MAP Kinases; Foam Cells; Gene Expression Regulation; Glucosides; Heme Oxygenase-1; Humans; Lipoproteins, LDL; MAP Kinase Kinase 4; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phenols; Proto-Oncogene Proteins c-akt; Scavenger Receptors, Class E; Signal Transduction; THP-1 Cells | 2017 |
[Effect of salidroside on the expression of connexin43 in the corpus cavernosum smooth muscle cells of hypoxic rats].
Topics: Actins; Animals; Cell Hypoxia; Cells, Cultured; Connexin 43; Glucosides; Male; Myocytes, Smooth Muscle; Penis; Phenols; Phosphorylation; Rats; Rats, Sprague-Dawley | 2016 |
Salidroside alleviates high glucose-induced oxidative stress and extracellular matrix accumulation in rat glomerular mesangial cells by the TXNIP-NLRP3 inflammasome pathway.
Topics: Animals; Carrier Proteins; Caspase 1; Cell Cycle Proteins; Cell Line; Collagen Type IV; Down-Regulation; Extracellular Matrix; Fibronectins; Glucose; Glucosides; Inflammasomes; Malondialdehyde; Mesangial Cells; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Phenols; Rats; Reactive Oxygen Species; RNA Interference; Signal Transduction; Superoxide Dismutase | 2017 |
Inhibiting ROS-TFEB-Dependent Autophagy Enhances Salidroside-Induced Apoptosis in Human Chondrosarcoma Cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Bone Neoplasms; Cell Line, Tumor; Chondrosarcoma; Glucosides; Humans; Phenols; Reactive Oxygen Species; Rhodiola; Signal Transduction | 2017 |
Salidroside could enhance the cytotoxic effect of L‑OHP on colorectal cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Resistance; Drug Synergism; Glucosides; HT29 Cells; Humans; Organoplatinum Compounds; Oxaliplatin; Phenols | 2018 |
Salidroside slows the progression of EA.hy926 cell senescence by regulating the cell cycle in an atherosclerosis model.
Topics: Animals; Atherosclerosis; Biomarkers; Cell Cycle; Cell Cycle Proteins; Cell Line; Cellular Senescence; Disease Models, Animal; Endothelial Cells; Gene Expression Regulation; Genes, p53; Glucosides; Humans; Phenols | 2018 |
Salidroside attenuates neuroinflammation and improves functional recovery after spinal cord injury through microglia polarization regulation.
Topics: Adenylate Kinase; Animals; Apoptosis; Autophagy; Cell Line; Cell Polarity; Female; Glucosides; Inflammation; Inflammation Mediators; Lipopolysaccharides; Macrophages; Mice; Microglia; Mitochondria; Models, Biological; Motor Activity; Neurons; Phenols; Rats, Sprague-Dawley; Recovery of Function; Signal Transduction; Spinal Cord Injuries; TOR Serine-Threonine Kinases | 2018 |
Inhibition of Complement Drives Increase in Early Growth Response Proteins and Neuroprotection Mediated by Salidroside After Cerebral Ischemia.
Topics: Animals; Brain Ischemia; Complement C3; Complement Inactivator Proteins; Complement System Proteins; Early Growth Response Transcription Factors; Glucosides; Infarction, Middle Cerebral Artery; Neuroprotection; Phenols; Rats; Reperfusion Injury; Time Factors | 2018 |
Salidroside attenuates hypoxia-induced pulmonary arterial smooth muscle cell proliferation and apoptosis resistance by upregulating autophagy through the AMPK-mTOR-ULK1 pathway.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Autophagy-Related Protein-1 Homolog; Cell Proliferation; Glucosides; Hypoxia; Male; Myocytes, Smooth Muscle; Phenols; Rats | 2017 |
Osteoprotective effects of salidroside in ovariectomized mice and diabetic mice.
Topics: Animals; Blood Glucose; Cytoprotection; Diabetes Mellitus, Type 1; Estrogens; Fasting; Femur; Gene Expression Regulation; Glucosides; Kidney; Mice; Mice, Inbred C57BL; Ovariectomy; Phenols; Vitamin D | 2018 |
Inhibition of autophagy enhances synergistic effects of Salidroside and anti-tumor agents against colorectal cancer.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Autophagy; Cell Survival; Colorectal Neoplasms; Drug Synergism; Glucosides; HCT116 Cells; Humans; Phenols; Rhodiola; Signal Transduction | 2017 |
Complete Pathway Elucidation and Heterologous Reconstitution of Rhodiola Salidroside Biosynthesis.
Topics: Acetaldehyde; Glucosides; Phenols; Phenylethyl Alcohol; Plant Proteins; Rhodiola; Saccharomyces cerevisiae | 2018 |
Salidroside inhibits steroid-induced avascular necrosis of the femoral head via the PI3K/Akt signaling pathway: In vitro and in vivo studies.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Survival; Cytochromes c; Dexamethasone; Femur Head Necrosis; Glucosides; Male; Mice; Mitochondria; Osteoblasts; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Salidroside attenuates endothelial cellular senescence via decreasing the expression of inflammatory cytokines and increasing the expression of SIRT3.
Topics: Animals; Anti-Inflammatory Agents; Aorta; beta-Galactosidase; Cells, Cultured; Cellular Senescence; Collagen; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cytokines; Disease Models, Animal; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Inflammation Mediators; Male; Mice, Inbred BALB C; Phenols; Sirtuin 3; Up-Regulation; Vascular Remodeling | 2018 |
Salidroside influences the cellular cross-talk of human fetal lung diploid fibroblasts: A proteomic approach.
Topics: Cell Line; Cellular Senescence; Diploidy; Fetus; Fibroblasts; Glucosides; Humans; Lung; Phenols; Proteome; Proteomics | 2018 |
Salidroside Inhibits HMGB1 Acetylation and Release through Upregulation of SirT1 during Inflammation.
Topics: Acetylation; AMP-Activated Protein Kinases; Animals; Cell Nucleus; Glucosides; HMGB1 Protein; Inflammation; Lipopolysaccharides; Lung; Mice; Phenols; Phosphorylation; Rats; Rats, Wistar; RAW 264.7 Cells; RNA Interference; RNA, Small Interfering; Sepsis; Signal Transduction; Sirtuin 1; Up-Regulation | 2017 |
Salidroside provides neuroprotection by modulating microglial polarization after cerebral ischemia.
Topics: Animals; Brain Ischemia; Cell Polarity; Cells, Cultured; Dose-Response Relationship, Drug; Glucosides; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroprotection; Phenols; Rats | 2018 |
Neuroprotective effects of salidroside administration in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Glucosides; Glutathione; Hippocampus; Male; Malondialdehyde; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Phenols; Superoxide Dismutase | 2018 |
Convergent engineering of syntrophic Escherichia coli coculture for efficient production of glycosides.
Topics: Escherichia coli; Glucosides; Metabolic Engineering; Phenols; Phenylethyl Alcohol; Uridine Diphosphate Glucose; Xylose | 2018 |
Salidroside improves brain ischemic injury by activating PI3K/Akt pathway and reduces complications induced by delayed tPA treatment.
Topics: Animals; Brain; Cell Survival; Cells, Cultured; Endothelial Cells; Glucosides; Humans; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Tissue Plasminogen Activator | 2018 |
Neuroprotective Effects of Four Phenylethanoid Glycosides on H₂O₂-Induced Apoptosis on PC12 Cells via the Nrf2/ARE Pathway.
Topics: Animals; Antioxidant Response Elements; Apoptosis; Glucosides; Glycosides; Hydrogen Peroxide; Neuroprotective Agents; NF-E2-Related Factor 2; PC12 Cells; Phenols; Protoporphyrins; Rats; Signal Transduction | 2018 |
Metabolic Engineering of Saccharomyces cerevisiae for High-Level Production of Salidroside from Glucose.
Topics: Fermentation; Gene Expression; Glucose; Glucosides; Metabolic Engineering; Microorganisms, Genetically-Modified; Petroselinum; Phenols; Phenylethyl Alcohol; Saccharomyces cerevisiae; Tyrosine | 2018 |
Salidroside Protects Against Advanced Glycation End Products-Induced Vascular Endothelial Dysfunction.
Topics: Animals; Aorta; Apoptosis; Cell Survival; Diabetes Complications; Disease Models, Animal; Endothelial Cells; Glucosides; Glycation End Products, Advanced; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; Male; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Phenols; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2018 |
Salidroside prevents skin carcinogenesis induced by DMBA/TPA in a mouse model through suppression of inflammation and promotion of apoptosis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Survival; Cytokines; Drug Administration Schedule; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Mice; Phenols; Random Allocation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2018 |
Insecticidal and
Topics: Animals; Drug Evaluation, Preclinical; Glucosides; Glycoside Hydrolase Inhibitors; Glycosides; Insecticides; Magnetic Resonance Spectroscopy; Molecular Structure; Moths; Phenols; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Viburnum | 2019 |
Salidroside Protection Against Oxidative Stress Injury Through the Wnt/β-Catenin Signaling Pathway in Rats with Parkinson's Disease.
Topics: Animals; Antioxidants; Apoptosis; Female; Glucosides; Male; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Parkinson Disease, Secondary; PC12 Cells; Phenols; Rats; Rats, Wistar; Wnt Signaling Pathway | 2018 |
Salidroside mediated stabilization of Bcl -x
Topics: Animals; Autophagy; bcl-X Protein; CA3 Region, Hippocampal; Glucosides; Hypoxia, Brain; Male; Mitophagy; Molecular Docking Simulation; Neurons; Phenols; Protein Structure, Secondary; Rats; Rats, Sprague-Dawley | 2018 |
Salidroside inhibits the proliferation and migration of gastric cancer cells via suppression of Src‑associated signaling pathway activation and heat shock protein 70 expression.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glucosides; HSP70 Heat-Shock Proteins; Humans; Neoplasm Proteins; Phenols; Signal Transduction; src-Family Kinases; Stomach Neoplasms | 2018 |
Topics: Animals; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction; Collagen; Glucosides; Humans; Joint Instability; Knee; Knee Injuries; Knee Joint; Magnetic Resonance Imaging; Male; Microspheres; Nerve Regeneration; Nerve Tissue; Peripheral Nerve Injuries; Phenols; Polyesters; Rats; Rats, Sprague-Dawley; Rats, Wistar; Retrospective Studies; Sciatic Nerve; Sciatic Neuropathy; Tibia; Tibial Meniscus Injuries; Tissue Engineering; Wound Healing | 2016 |
Salidroside protects hypoxia-induced injury by up-regulation of miR-210 in rat neural stem cells.
Topics: Animals; Apoptosis; Cell Hypoxia; Glucosides; Humans; MicroRNAs; Neural Stem Cells; Neuroprotective Agents; Phenols; Phosphatidylinositol 3-Kinases; Proteins; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation | 2018 |
Phenolic glycoside constituents from
Topics: Brassica rapa; Drug Evaluation, Preclinical; Flowers; Glucosides; Glycoside Hydrolase Inhibitors; Glycosides; Magnetic Resonance Spectroscopy; Molecular Structure; Phenols; Plant Extracts | 2019 |
Salidroside inhibits migration, invasion and angiogenesis of MDA‑MB 231 TNBC cells by regulating EGFR/Jak2/STAT3 signaling via MMP2.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Movement; Cell Survival; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Janus Kinase 2; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Phenols; Signal Transduction; STAT3 Transcription Factor; Triple Negative Breast Neoplasms | 2018 |
[Effect of endophytic fungus on expression of key enzyme genes in pathway of salidroside biosynthesis in Rhodiola crenulata].
Topics: Biosynthetic Pathways; Endophytes; Glucosides; Glucuronosyltransferase; Phenols; Phenylalanine Ammonia-Lyase; Plant Proteins; Rhodiola; Tyrosine Decarboxylase; Tyrosine Transaminase | 2016 |
[Salidroside inhibits inflammatory factor release in BV-2 cells through p38 and JNK pathways].
Topics: Animals; Anthracenes; Apoptosis; Cell Survival; Cells, Cultured; Glucosides; Imidazoles; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Microglia; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Pyridines; Tumor Necrosis Factor-alpha | 2018 |
Salidroside protects renal tubular epithelial cells from hypoxia/reoxygenation injury in vitro.
Topics: Anti-Inflammatory Agents; Antioxidants; bcl-2-Associated X Protein; Caspase 3; Cell Survival; Cells, Cultured; Epithelial Cells; Glucosides; Humans; Interleukin-1beta; Interleukin-6; Ischemia; Kidney; Kidney Tubules; Malondialdehyde; NF-kappa B; Phenols; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Superoxide Dismutase; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2018 |
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Topics: Animals; Autophagy; Glucosides; Hepatic Stellate Cells; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Phenols; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1 | 2018 |
[Simultaneous determination of salidroside and tyrosol in Beagle dog plasma using UHPLC-MS/MS after pre-column dansyl chloride derivatization].
Topics: Animals; Chromatography, High Pressure Liquid; Dansyl Compounds; Dogs; Glucosides; Phenols; Phenylethyl Alcohol; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2017 |
Simultaneous Preparation of Salidroside and
Topics: Chromatography, Gel; Coumarins; Drugs, Chinese Herbal; Glucosides; Phenols; Phenylethyl Alcohol; Polystyrenes; Resins, Plant; Rhizome; Rhodiola; Silica Gel; Silicon Dioxide | 2018 |
A validated LC-MS/MS method for the determination of specnuezhenide and salidroside in rat plasma and its application to a pharmacokinetic study.
Topics: Animals; Chromatography, Liquid; Glucosides; Linear Models; Male; Phenols; Pyrans; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2018 |
A Comprehensive Quality Evaluation Method Based on C
Topics: Antioxidants; Apigenin; Chromatography, High Pressure Liquid; Coumarins; Drugs, Chinese Herbal; Fruit; Glucosides; Glycosides; Isomerism; Ligustrum; Limit of Detection; Oleanolic Acid; Phenols; Pyrans; Reproducibility of Results; Triterpenes; Ursolic Acid | 2018 |
Salidroside alleviates ischemic brain injury in mice with ischemic stroke through regulating BDNK mediated PI3K/Akt pathway.
Topics: Animals; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cells, Cultured; Embryo, Mammalian; Forkhead Box Protein O1; Gene Expression Regulation; Glucosides; Male; Mice; Mice, Knockout; Neurons; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RNA Interference; Stroke | 2018 |
Salidroside mitigates hypoxia/reoxygenation injury by alleviating endoplasmic reticulum stress‑induced apoptosis in H9c2 cardiomyocytes.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Hypoxia; Cell Line; Endoplasmic Reticulum Stress; Glucosides; Hypoxia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phenols; Rats; Signal Transduction | 2018 |
Salidroside Attenuates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via AMPK-Dependent TXNIP/NLRP3 Pathway.
Topics: Animals; Diet, High-Fat; Glucosides; Male; Mice; Non-alcoholic Fatty Liver Disease; Phenols; Rhodiola | 2018 |
Salidroside and Curcumin Formula Prevents Liver Injury in Nonalcoholic Fatty Liver Disease in Rats.
Topics: AMP-Activated Protein Kinases; Animals; Biomarkers; Blood Glucose; Curcumin; Diet, High-Fat; Disease Models, Animal; Drug Combinations; Glucosides; Insulin; Insulin Resistance; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Non-alcoholic Fatty Liver Disease; Phenols; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Parkin-mediated mitophagy as a potential therapeutic target for intervertebral disc degeneration.
Topics: Animals; Apoptosis; Autophagy; Cells, Cultured; Disease Models, Animal; Disease Progression; Gene Knockdown Techniques; Glucosides; Humans; Intervertebral Disc Degeneration; Male; Mitochondria; Mitophagy; Nucleus Pulposus; Phenols; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Transfection; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases; Up-Regulation | 2018 |
Frontline Science: Reprogramming COX-2, 5-LOX, and CYP4A-mediated arachidonic acid metabolism in macrophages by salidroside alleviates gouty arthritis.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arthritis, Gouty; Cell Movement; Cell Polarity; Chondrocytes; Crystallization; Cyclooxygenase 2; Cytochrome P-450 CYP4A; Disease Models, Animal; Down-Regulation; Glucosides; Interleukin-1beta; Macrophages; Male; Mice; Models, Biological; Neutrophils; NF-kappa B; Phenols; Phenotype; Rabbits; Rats, Wistar; RAW 264.7 Cells; Signal Transduction; STAT1 Transcription Factor; Synovial Fluid; Tumor Necrosis Factor-alpha; Uric Acid | 2019 |
Antidepressant-like effect of salidroside and curcumin on the immunoreactivity of rats subjected to a chronic mild stress model.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Curcumin; Exploratory Behavior; Glucosides; Lipopolysaccharides; Male; Motor Activity; Phenols; Random Allocation; Rats; Rats, Wistar; Stress, Physiological; Stress, Psychological; Time Factors | 2018 |
RETRACTED: Salidroside protects LPS-induced injury in human thyroid follicular epithelial cells by upregulation of MiR-27a.
Topics: Apoptosis; Cell Survival; Chemokine CCL2; Epithelial Cells; Glucosides; Humans; Inflammation; Interleukin-6; Lipopolysaccharides; MicroRNAs; NF-kappa B; Phenols; Receptors, Notch; Signal Transduction; Thyroid Gland; Transcriptional Activation; Tumor Necrosis Factor-alpha; Up-Regulation | 2018 |
Salidroside prevents diabetes‑induced cognitive impairment via regulating the Rho pathway.
Topics: Animals; Apoptosis; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Gene Expression Regulation; Glucosides; Male; Oxidative Stress; Phenols; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction | 2019 |
Modulation of hepatic lipidome by rhodioloside in high-fat diet fed apolipoprotein E knockout mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Chromatography, Liquid; Diet, High-Fat; Dyslipidemias; Glucosides; Lipid Metabolism; Lipids; Liver; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Knockout, ApoE; Phenols; Tandem Mass Spectrometry | 2020 |
Salidroside improves the hypoxic tumor microenvironment and reverses the drug resistance of platinum drugs via HIF-1α signaling pathway.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Computational Biology; Disease Models, Animal; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Profiling; Glucosides; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Mice; Phenols; Signal Transduction; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2018 |
Identification and Microbial Production of the Raspberry Phenol Salidroside that Is Active against Huntington's Disease.
Topics: Biosynthetic Pathways; Chemical Fractionation; Glucosides; Huntingtin Protein; Huntington Disease; Models, Biological; Phenols; Plant Extracts; Rubus; Saccharomyces cerevisiae | 2019 |
Effect of salidroside on bone marrow haematopoiesis in a mouse model of myelosuppressed anaemia.
Topics: Anemia; Animals; Bone Marrow; Bone Marrow Transplantation; Cell Count; Cell Lineage; Cell Proliferation; Disease Models, Animal; Glucosides; Hematopoiesis; Hematopoietic Stem Cells; Immunosuppression Therapy; Male; Mice; Pancytopenia; Phenols; Survival Analysis | 2019 |
Ancient herbal component may be a novel therapeutic for gouty arthritis.
Topics: Arachidonic Acids; Arthritis, Gouty; Cyclooxygenase 2; Cytochrome P-450 CYP4A; Glucosides; Humans; Macrophages; Phenols | 2019 |
Human leukemia cells (HL-60) proteomic and biological signatures underpinning cryo-damage are differentially modulated by novel cryo-additives.
Topics: Cell Proliferation; Cryopreservation; Cryoprotective Agents; Disaccharides; Glucosides; HL-60 Cells; Humans; Lipid Peroxidation; Oxidation-Reduction; Phenols; Protein Carbonylation; Proteome; Proteomics | 2019 |
Salidroside protected against MPP
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Glucosides; Inflammation; MPTP Poisoning; Oxidative Stress; PC12 Cells; Phenols; Rats | 2019 |
Salidroside inhibits platelet-derived growth factor-induced proliferation and migration of airway smooth muscle cells.
Topics: Airway Remodeling; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Glucosides; Male; Myocytes, Smooth Muscle; Phenols; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley | 2019 |
Salidroside protects ATDC5 cells against lipopolysaccharide-induced injury through up-regulation of microRNA-145 in osteoarthritis.
Topics: Animals; Cell Line; Cell Survival; Chondrocytes; Gene Expression Regulation; Glucosides; Lipopolysaccharides; Mice; MicroRNAs; Osteoarthritis; Phenols; Up-Regulation | 2019 |
Salidroside-Pretreated Mesenchymal Stem Cells Enhance Diabetic Wound Healing by Promoting Paracrine Function and Survival of Mesenchymal Stem Cells Under Hyperglycemia.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Glucosides; Hyperglycemia; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Paracrine Communication; Phenols; Survival Rate; Wound Healing | 2019 |
Ameliorative effect of salidroside from Rhodiola Rosea L. on the gut microbiota subject to furan-induced liver injury in a mouse model.
Topics: Animals; Bacteria; Chemical and Drug Induced Liver Injury; Cytokines; DNA, Bacterial; DNA, Ribosomal; Dysbiosis; Furans; Gastrointestinal Microbiome; Glucosides; Inflammation; Lipopolysaccharides; Liver; Male; Mice, Inbred BALB C; Phenols; Proteobacteria; Rhodiola; Verrucomicrobia | 2019 |
Salidroside promotes rat spinal cord injury recovery by inhibiting inflammatory cytokine expression and NF-κB and MAPK signaling pathways.
Topics: Animals; Astrocytes; Cytokines; Disease Models, Animal; Gene Expression Regulation; Glucosides; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenols; Rats; Signal Transduction; Spinal Cord Injuries; Tumor Necrosis Factor-alpha | 2019 |
Protective Effects of Salidroside on Lead Acetate-induced Oxidative Stress and Hepatotoxicity in Sprague-Dawley Rats.
Topics: Animals; Antioxidants; Body Weight; Cytochrome P-450 CYP2E1; Female; Glucosides; Humans; Immunohistochemistry; Lead; Liver; NADPH Oxidase 2; Oxidative Stress; Phenols; Rats; Rats, Sprague-Dawley; Temperature | 2019 |
Salidroside stimulates the Sirt1/PGC-1α axis and ameliorates diabetic nephropathy in mice.
Topics: Animals; Diabetic Nephropathies; Disease Models, Animal; DNA, Mitochondrial; Electron Transport; Glucosides; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Mitochondria; Phenols; Podocytes; Sirtuin 1; Streptozocin; Transcription Factors; Up-Regulation | 2019 |
Enzymatic Glucosylation of Salidroside from Starch by α-Amylase.
Topics: alpha-Amylases; Bacillus subtilis; Glucosides; Glycosylation; Hydrolysis; Maltose; Oligosaccharides; Phenols; Starch | 2019 |
Salidroside protects PC-12 cells against amyloid β-induced apoptosis by activation of the ERK1/2 and AKT signaling pathways.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Caspase 3; Caspase 7; Cytoprotection; Glucosides; L-Lactate Dehydrogenase; Malondialdehyde; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Neuroprotective Agents; PC12 Cells; Phenols; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Superoxide Dismutase | 2019 |
RETRACTED: Salidroside inhibits the growth, migration and invasion of Wilms' tumor cells through down-regulation of miR-891b.
Topics: Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Glucosides; Humans; MicroRNAs; Neoplasm Invasiveness; Phenols; Wilms Tumor | 2019 |
Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways.
Topics: Cadherins; Cell Line; Cytokines; Epithelial-Mesenchymal Transition; Extracellular Matrix; Fibrosis; Gene Expression Regulation; Glucosides; Humans; Kidney; Kidney Diseases; Kidney Tubules, Proximal; MAP Kinase Signaling System; NF-kappa B; Phenols; Rhodiola; Toll-Like Receptor 4 | 2019 |
Salidroside Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis by Inhibiting the Hypoxia-Inducible Factor-1α Expression Through Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway.
Topics: Animals; Doxorubicin; Glomerulosclerosis, Focal Segmental; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Inbred C57BL; Oxidative Stress; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2019 |
Neuroprotective effect of salidroside against central nervous system inflammation-induced cognitive deficits: A pivotal role of sirtuin 1-dependent Nrf-2/HO-1/NF-κB pathway.
Topics: Animals; Antioxidants; Apoptosis; Cognition; Cytokines; Glucosides; Hippocampus; Inflammation; Lipopolysaccharides; Neuroprotective Agents; NF-kappa B; PC12 Cells; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1; Superoxide Dismutase | 2019 |
Salidroside Reduces PDE2A Expression by Down-regulating p53 in Human Embryonic Lung Fibroblasts.
Topics: Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 2; Fibroblasts; Glucosides; Humans; Lung; Phenols; Phosphodiesterase Inhibitors; Tumor Suppressor Protein p53 | 2019 |
Salidroside represses proliferation, migration and invasion of human lung cancer cells through AKT and MEK/ERK signal pathway.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Glucosides; Humans; Lung Neoplasms; MAP Kinase Signaling System; MicroRNAs; Neoplasm Invasiveness; Phenols; Proto-Oncogene Proteins c-akt; Up-Regulation | 2019 |
Phenylalkanoid Glycosides (Non-Salicinoids) from Wood Chips of
Topics: Allyl Compounds; Arabinose; Chromatography, High Pressure Liquid; Glucosides; Glycosides; Metabolome; Pentoses; Phenols; Rhamnose; Salix; Wood; Xylose | 2019 |
Authentication of
Topics: Chromatography, Thin Layer; Drug Contamination; Glucosides; Phenols; Plant Extracts; Rhodiola; Ukraine | 2020 |
Salidroside suppresses the metastasis of hepatocellular carcinoma cells by inhibiting the activation of the Notch1 signaling pathway.
Topics: Cadherins; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cyclooxygenase 2; Down-Regulation; Glucosides; Humans; Liver Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Phenols; Receptor, Notch1; Signal Transduction; Snail Family Transcription Factors; Transcription Factor HES-1 | 2019 |
Salidroside attenuates oxidized low‑density lipoprotein‑induced endothelial cell injury via promotion of the AMPK/SIRT1 pathway.
Topics: AMP-Activated Protein Kinases; Antioxidants; Apoptosis; Cell Survival; Cytoprotection; Endothelial Cells; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Lipoproteins, LDL; Oxidative Stress; Phenols; Reactive Oxygen Species; Rhodiola; Signal Transduction; Sirtuin 1 | 2019 |
Salidroside protects inner ear hair cells and spiral ganglion neurons from manganese exposure by regulating ROS levels and inhibiting apoptosis.
Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Chlorides; Cytoprotection; Dose-Response Relationship, Drug; Glucosides; Hair Cells, Auditory, Inner; Manganese Compounds; Neuroprotective Agents; Oxidative Stress; Phenols; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Spiral Ganglion; Tissue Culture Techniques | 2019 |
Salidroside ameliorates Adriamycin nephropathy in mice by inhibiting β-catenin activity.
Topics: Animals; Antibiotics, Antineoplastic; beta Catenin; Doxorubicin; Gene Expression Regulation; Glucosides; Kidney Diseases; Male; Mice; Mice, Inbred BALB C; Phenols; Podocytes; Proteinuria; Signal Transduction | 2019 |
Preparation of molecularly imprinted polymers coupled with high-performance liquid chromatography for the selective extraction of salidroside from Rhodiola crenulata.
Topics: Chromatography, High Pressure Liquid; Glucosides; Limit of Detection; Linear Models; Molecular Imprinting; Phenols; Plant Extracts; Reproducibility of Results; Rhodiola; Solid Phase Extraction | 2019 |
Salidroside suppresses the growth and invasion of human osteosarcoma cell lines MG63 and U2OS in vitro by inhibiting the JAK2/STAT3 signaling pathway.
Topics: Antineoplastic Agents; Bone Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Janus Kinase 2; Osteosarcoma; Phenols; Signal Transduction; STAT3 Transcription Factor | 2019 |
[Qualitative and quantitative analysis on non-triterpenoids in Ligustri Lucidi Fructus].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fruit; Furaldehyde; Glucosides; Iridoid Glycosides; Ligustrum; Phenols; Phytochemicals | 2019 |
Effects of Salidroside on Trabecular Meshwork Cell Extracellular Matrix Expression and Mouse Intraocular Pressure.
Topics: Animals; Cells, Cultured; Collagen Type IV; Extracellular Matrix; Fibronectins; Glucosides; Humans; Injections, Intraperitoneal; Intraocular Pressure; Laminin; Mice; Ocular Hypertension; Phenols; Trabecular Meshwork; Transforming Growth Factor beta2 | 2019 |
Salidroside inhibits migration and invasion of poorly differentiated thyroid cancer cells.
Topics: Cell Line, Tumor; Cell Movement; Cell Survival; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Janus Kinase 2; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Phenols; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; Thyroid Neoplasms | 2019 |
[Effects and mechanism of salidroside on streptozotocin-induced mode rats of diabetic nephropathy].
Topics: Animals; Diabetic Nephropathies; Glucosides; Kidney; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; Transforming Growth Factor beta1 | 2019 |
Salidroside protects against ox-LDL-induced endothelial injury by enhancing autophagy mediated by SIRT1-FoxO1 pathway.
Topics: Atherosclerosis; Autophagy; Drug Evaluation, Preclinical; Endothelial Cells; Forkhead Box Protein O1; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Lipoproteins, LDL; Oxidative Stress; Phenols; Phytotherapy; Plant Extracts; Rhodiola; Sirtuin 1 | 2019 |
Salidroside ameliorated hypoxia-induced tumorigenesis of BxPC-3 cells via downregulating hypoxia-inducible factor (HIF)-1α and LOXL2.
Topics: Amino Acid Oxidoreductases; Animals; Antineoplastic Agents; Cadherins; Carcinogenesis; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Disulfides; Down-Regulation; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Pancreatic Neoplasms; Phenols; Sulfonamides | 2020 |
Salidroside protects SH‑SY5Y from pathogenic α‑synuclein by promoting cell autophagy via mediation of mTOR/p70S6K signaling.
Topics: alpha-Synuclein; Autophagy; Cell Line; Glucosides; Humans; Neuroprotective Agents; Parkinson Disease; Phenols; Point Mutation; Rhodiola; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases | 2019 |
Salidroside Reduces Inflammation and Brain Injury After Permanent Middle Cerebral Artery Occlusion in Rats by Regulating PI3K/PKB/Nrf2/NFκB Signaling Rather than Complement C3 Activity.
Topics: Animals; Brain Injuries; Brain Ischemia; Complement C3; Glucosides; Infarction, Middle Cerebral Artery; Inflammation; Neuroprotection; NF-E2-Related Factor 2; Phenols; Phosphatidylinositol 3-Kinases; Rats; Signal Transduction | 2019 |
Salidroside alleviates high-glucose-induced injury in retinal pigment epithelial cell line ARPE-19 by down-regulation of miR-138.
Topics: 3' Untranslated Regions; Apoptosis; Cell Survival; Epithelial Cells; Gene Expression Regulation; Genes, Reporter; Glucose; Glucosides; Humans; MAP Kinase Signaling System; MicroRNAs; Oxidative Stress; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Retinal Pigment Epithelium; RNA Interference; Sirtuin 1 | 2019 |
[Microbial synthesis of salidroside].
Topics: Biosynthetic Pathways; Glucosides; Phenols | 2019 |
Salidroside Inhibits Lipopolysaccharide-ethanol-induced Activation of Proinflammatory Macrophages via Notch Signaling Pathway.
Topics: Cytokines; Ethanol; Gene Expression Regulation; Glucosides; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Liver; Macrophages; NF-kappa B; Phenols; Protein Phosphatase 2C; Receptors, Notch; Rhodiola; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha | 2019 |
Salidroside and FG-4592 ameliorate high glucose-induced glomerular endothelial cells injury via HIF upregulation.
Topics: Animals; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Cell Survival; Cells, Cultured; Diabetic Nephropathies; Endothelial Cells; Glucose; Glucosides; Glycine; Hypoxia-Inducible Factor 1, alpha Subunit; Isoquinolines; Kidney Glomerulus; Phenols; Protein Stability; Rats; Up-Regulation | 2019 |
Salidroside Suppresses IL-1β-Induced Apoptosis in Chondrocytes via Phosphatidylinositol 3-Kinases (PI3K)/Akt Signaling Inhibition.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Proliferation; China; Chondrocytes; Glucosides; Inflammation; Interleukin-1beta; Nitric Oxide; Osteoarthritis; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2019 |
Salidroside attenuates dextran sulfate sodium-induced colitis in mice via SIRT1/FoxOs signaling pathway.
Topics: Animals; Apoptosis; Colitis; Colon; Dextran Sulfate; Forkhead Transcription Factors; Glucosides; Male; Mice; Mice, Inbred C57BL; Organ Size; Oxidative Stress; Phenols; Signal Transduction; Sirtuin 1 | 2019 |
[Effects of salidroside on the secretion of inflammatory mediators induced by lipopolysaccharide in the co-culture of rat alveolar macrophages and type II alveolar epithelial cells].
Topics: Alveolar Epithelial Cells; Animals; Cell Line; Chemokine CXCL2; Coculture Techniques; Glucosides; Interleukin-10; Lipopolysaccharides; Macrophages, Alveolar; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Tumor Necrosis Factor-alpha | 2019 |
Salidroside pretreatment protects against myocardial injury induced by heat stroke in mice.
Topics: Animals; Body Temperature Regulation; Cardiotonic Agents; Glucosides; Heat Stroke; Inflammation; Interleukin-6; Male; Malondialdehyde; Mice; Myocardium; Myocytes, Cardiac; Oxidative Stress; Phenols; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha | 2019 |
Salidroside protects dopaminergic neurons by regulating the mitochondrial MEF2D-ND6 pathway in the MPTP/MPP
Topics: Animals; Cell Survival; Dopaminergic Neurons; Glucosides; Male; MEF2 Transcription Factors; Mice; Mice, Inbred C57BL; Mitochondria; NADH Dehydrogenase; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Phenols; Signal Transduction | 2020 |
Salidroside Delays Cellular Senescence by Stimulating Mitochondrial Biogenesis Partly through a miR-22/SIRT-1 Pathway.
Topics: Cellular Senescence; Glucosides; Humans; MicroRNAs; Mitochondria; Organelle Biogenesis; Phenols; Rhodiola | 2019 |
Protective effects of Salidroside on spermatogenesis in streptozotocin induced type-1 diabetic male mice by inhibiting oxidative stress mediated blood-testis barrier damage.
Topics: Animals; Antioxidants; Blood-Testis Barrier; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucosides; Glutathione; Male; Malondialdehyde; Mice; Oxidative Stress; Phenols; Protective Agents; Reactive Oxygen Species; Sperm Count; Spermatogenesis; Spermatozoa; Streptozocin; Superoxide Dismutase; Testis | 2020 |
Salidroside Restores an Anti-inflammatory Endothelial Phenotype by Selectively Inhibiting Endothelial Complement After Oxidative Stress.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis Regulatory Proteins; Brain; Cell Line; Coculture Techniques; Complement Activation; Complement C3; Complement Inactivating Agents; Disease Models, Animal; Endothelial Cells; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Infarction, Middle Cerebral Artery; Inflammation Mediators; Male; Mice; Oxidative Stress; Phenols; Phenotype; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2020 |
[The effects of salidroside on the apoptosis pathway of myocardial cells in acute exhausted rats].
Topics: Animals; Apoptosis; Biomarkers; Fatigue; Female; Glucosides; Heart; Male; Myocardial Ischemia; Myocardium; Phenols; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley | 2019 |
Salidroside mitigates skeletal muscle atrophy in rats with cigarette smoke-induced COPD by up-regulating myogenin and down-regulating myostatin expression.
Topics: Animals; Antioxidants; Disease Models, Animal; Down-Regulation; Glucosides; Lung; Male; Muscle, Skeletal; Muscular Atrophy; Myogenin; Myostatin; Nicotiana; Phenols; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Rats; Rats, Wistar; Smoke; Smoking; Up-Regulation | 2019 |
Salidroside ameliorates endothelial inflammation and oxidative stress by regulating the AMPK/NF-κB/NLRP3 signaling pathway in AGEs-induced HUVECs.
Topics: AMP-Activated Protein Kinases; Cell Line; Diabetic Angiopathies; Endothelium, Vascular; Glucosides; Glycation End Products, Advanced; Human Umbilical Vein Endothelial Cells; Humans; Inflammasomes; Inflammation; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Phenols; Reactive Oxygen Species; RNA-Seq; Signal Transduction; Transcription Factor RelA | 2020 |
Analysis of five active ingredients of Er-Zhi-Wan, a traditional Chinese medicine water-honeyed pill, using the biopharmaceutics classification system.
Topics: Animals; Biological Availability; Caco-2 Cells; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Humans; Intestinal Absorption; Limit of Detection; Linear Models; Luteolin; Male; Oleanolic Acid; Permeability; Phenols; Pyrans; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Software; Solubility | 2020 |
Protective effects of Salidroside on cardiac function in mice with myocardial infarction.
Topics: Animals; Apoptosis; Cardiotonic Agents; Coronary Vessels; Cytokines; Disease Models, Animal; Fibrosis; Glucosides; Heart; Ligation; Male; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; Phenols; Ventricular Remodeling | 2019 |
Anti-insulin resistance effects of salidroside through mitochondrial quality control.
Topics: AMP-Activated Protein Kinases; Animals; Diabetes Mellitus; Glucose; Glucosides; Humans; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mitochondria; Phenols; Reactive Oxygen Species; Sirtuin 1 | 2020 |
[Salidroside induces anti-tumor effect in dendritic cells via ERK pathway].
Topics: Animals; Carcinoma, Lewis Lung; Cells, Cultured; Dendritic Cells; Glucosides; Interleukin-12; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Phenols; T-Lymphocytes, Cytotoxic | 2019 |
Metabolic profiling reveals that salidroside antagonizes hypoxic injury via modulating energy and lipid metabolism in cardiomyocytes.
Topics: Animals; Apoptosis; Cell Hypoxia; Cell Line; Cell Survival; Glucosides; Lipid Metabolism; Metabolic Networks and Pathways; Metabolomics; Myocytes, Cardiac; Phenols; Rats | 2020 |
Salidroside induces apoptosis and protective autophagy in human gastric cancer AGS cells through the PI3K/Akt/mTOR pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Death; Cell Line, Tumor; Cell Proliferation; Female; Glucosides; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Phenols; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Stomach Neoplasms; TOR Serine-Threonine Kinases | 2020 |
Salidroside enhances proliferation and maintains phenotype of articular chondrocytes for autologous chondrocyte implantation (ACI) via TGF-β/Smad3 Signal.
Topics: Animals; Cartilage, Articular; Cell Proliferation; Cell Survival; Cell Transplantation; Chondrocytes; Collagen Type I; Extracellular Matrix; Glucosides; Phenols; Primary Cell Culture; Rats, Sprague-Dawley; Smad3 Protein; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transplantation, Autologous | 2020 |
Salidroside improves high-fat diet-induced non-alcoholic steatohepatitis by regulating the gut microbiota-bile acid-farnesoid X receptor axis.
Topics: Animals; Bile Acids and Salts; Diet, High-Fat; Disease Models, Animal; Gastrointestinal Microbiome; Glucosides; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phenols; Receptors, Cytoplasmic and Nuclear; Triglycerides | 2020 |
Preparation and Characterization of PLGA-PEG-PLGA Nanoparticles Containing Salidroside and Tamoxifen for Breast Cancer Therapy.
Topics: Animals; Breast Neoplasms; Drug Delivery Systems; Female; Glucosides; Humans; Mice; Mice, Inbred BALB C; Nanoparticles; Phenols; Polyethylene Glycols; Polyglactin 910; Rats; Rats, Sprague-Dawley; Tamoxifen | 2020 |
Neuroprotective Effects of Salidroside in a Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognitive Dysfunction; Disease Models, Animal; Glucosides; Mice, Inbred C57BL; Mice, Transgenic; Neuroprotective Agents; Phenols; Phosphatidylinositol 3-Kinases; Signal Transduction; TOR Serine-Threonine Kinases | 2020 |
Rhodiola rosea L. modulates inflammatory processes in a CRH-activated BV2 cell model.
Topics: Adaptation, Biological; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Corticotropin-Releasing Hormone; Glucosides; HSP70 Heat-Shock Proteins; Inflammation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Microglia; NF-kappa B; Phenols; Plant Extracts; Plant Roots; Plants, Medicinal; Rhizome; Rhodiola; Stress, Physiological | 2020 |
Salidroside ameliorates diabetic nephropathy in rats by activating renal AMPK/SIRT1 signaling pathway.
Topics: AMP-Activated Protein Kinases; Animals; Diabetes Mellitus; Diabetic Nephropathies; Glucosides; Kidney; Phenols; Rats; Signal Transduction; Sirtuin 1 | 2020 |
Salidroside promotes sciatic nerve regeneration following combined application epimysium conduit and Schwann cells in rats.
Topics: Animals; Glucosides; Guided Tissue Regeneration; Male; Movement; Muscle, Skeletal; Myelin Sheath; Nerve Regeneration; Phenols; Rats; Rats, Sprague-Dawley; Schwann Cells; Sciatic Nerve; Sciatic Neuropathy | 2020 |
Amelioration of experimental autoimmune encephalomyelitis by Rhodiola rosea, a natural adaptogen.
Topics: Animals; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Encephalomyelitis, Autoimmune, Experimental; Female; Glucosides; Mice; Mice, Inbred C57BL; Phenols; Random Allocation; Rhodiola | 2020 |
Salidroside suppresses group 2 innate lymphoid cell-mediated allergic airway inflammation by targeting IL-33/ST2 axis.
Topics: Animals; Asthma; Cytokines; Disease Models, Animal; Female; Glucosides; Humans; Hypersensitivity; Immunity, Innate; Immunosuppressive Agents; Interleukin-1 Receptor-Like 1 Protein; Interleukin-33; Lymphocytes; Mice; Mice, Inbred C57BL; Phenols; Pneumonia; Respiratory System; Rhodiola; Signal Transduction; Th2 Cells | 2020 |
Salidroside Decreases Atherosclerosis Plaque Formation via Inhibiting Endothelial Cell Pyroptosis.
Topics: Animals; Atherosclerosis; Dose-Response Relationship, Drug; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Knockout; Phenols; Plaque, Atherosclerotic; Pyroptosis; Rhodiola | 2020 |
Sodium dodecyl sulfate improved stability and transdermal delivery of salidroside-encapsulated niosomes via effects on zeta potential.
Topics: Administration, Cutaneous; Animals; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Drug Stability; Glucosides; Humans; Liposomes; Male; Particle Size; Phenols; Rats; Rats, Sprague-Dawley; Skin Absorption; Sodium Dodecyl Sulfate; Surface-Active Agents | 2020 |
[Inhibitory effect of salidroside on H2O2-induced down-regulation of Cx43 expression in corpus cavernosum smooth muscle cells in rats].
Topics: Animals; Cells, Cultured; Connexin 43; Down-Regulation; Gene Expression Regulation; Glucosides; Hydrogen Peroxide; Male; Myocytes, Smooth Muscle; Penis; Phenols; Rats | 2019 |
Salidroside ameliorates liver metabonomics in relation to modified gut-liver FXR signaling in furan-induced mice.
Topics: Animals; Dose-Response Relationship, Drug; Furans; Glucosides; Intestines; Liver; Metabolomics; Mice; Phenols; Receptors, Cytoplasmic and Nuclear; Signal Transduction | 2020 |
Salidroside suppresses nonsmall cell lung cancer cells proliferation and migration via microRNA-103-3p/Mzb1.
Topics: A549 Cells; Adaptor Proteins, Signal Transducing; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Glucosides; Humans; Lung Neoplasms; MicroRNAs; Neoplasm Metastasis; Phenols | 2020 |
Contribution of salidroside to the relieve of symptom and sign in the early acute stage of osteoarthritis in rat model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cartilage, Articular; Chondrocytes; Cytokines; Female; Glucosides; Inflammation; Injections, Intravenous; Iodoacetic Acid; Knee Joint; Osteoarthritis; Pain; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction; Synovial Fluid; Synovial Membrane | 2020 |
Salidroside Alleviates Cartilage Degeneration Through NF-κB Pathway in Osteoarthritis Rats.
Topics: Animals; Cartilage, Articular; Cell Proliferation; Chondrocytes; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glucosides; Injections, Intraperitoneal; NF-kappa B; Osteoarthritis; Phenols; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2020 |
Rewiring central carbon metabolism for tyrosol and salidroside production in Saccharomyces cerevisiae.
Topics: Biosynthetic Pathways; Carbon; Fermentation; Glucose; Glucosides; Metabolic Engineering; Phenols; Phenylethyl Alcohol; Saccharomyces cerevisiae | 2020 |
Salidroside ameliorates Parkinson's disease by inhibiting NLRP3-dependent pyroptosis.
Topics: Animals; Disease Models, Animal; Glucosides; Male; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Parkinson Disease; Phenols; Pyroptosis; Signal Transduction | 2020 |
Salidroside induces apoptosis and triggers endoplasmic reticulum stress in human hepatocellular carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Endoplasmic Reticulum Stress; Glucosides; Hep G2 Cells; Humans; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Phenols; Rhodiola | 2020 |
Therapeutic Effects of Salidroside on Cognitive Ability in Rats with Experimental Vascular Dementia.
Topics: Animals; Brain; Cognition; Dementia, Vascular; Disease Models, Animal; Glucosides; Male; Malondialdehyde; Maze Learning; Morris Water Maze Test; Neuroprotective Agents; Oxidative Stress; Phenols; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2020 |
Fibroblast growth factor 2 contributes to the effect of salidroside on dendritic and synaptic plasticity after cerebral ischemia/reperfusion injury.
Topics: Animals; Apoptosis; Cyclic AMP-Dependent Protein Kinases; Dendrites; Fibroblast Growth Factor 2; Glucosides; Infarction, Middle Cerebral Artery; Inflammation; Male; Neuronal Plasticity; Neuroprotective Agents; Phenols; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2020 |
Salidroside protects mice against CCl4-induced acute liver injury via down-regulating CYP2E1 expression and inhibiting NLRP3 inflammasome activation.
Topics: Animals; Carbon Tetrachloride; Caspases; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytokines; Down-Regulation; Glucosides; Inflammasomes; Liver; Male; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Phenols; Protective Agents | 2020 |
Salidroside Attenuates Hypoxia-Induced Expression of Connexin 43 in Corpus Cavernosum Smooth Muscle Cells.
Topics: Animals; Cell Hypoxia; Connexin 43; Glucosides; Male; Myocytes, Smooth Muscle; Penis; Phenols; Rats; Rats, Sprague-Dawley | 2020 |
Salidroside Attenuates Doxorubicin-Induced Cardiac Dysfunction Partially Through Activation of QKI/FoxO1 Pathway.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cardiotoxicity; Cell Line; Disease Models, Animal; Doxorubicin; Forkhead Box Protein O1; Glucosides; Heart Diseases; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Nerve Tissue Proteins; Oxidative Stress; Phenols; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA-Binding Proteins; Signal Transduction; Ventricular Function, Left | 2021 |
Salidroside-Mediated Autophagic Targeting of Active Src and Caveolin-1 Suppresses Low-Density Lipoprotein Transcytosis across Endothelial Cells.
Topics: Animals; Autophagy; Caveolin 1; Endothelial Cells; Glucosides; Humans; Lipoproteins, LDL; Mice; Phenols; src-Family Kinases; Transcytosis; Transfection | 2020 |
Salidroside alleviated hypoxia-induced liver injury by inhibiting endoplasmic reticulum stress-mediated apoptosis via IRE1α/JNK pathway.
Topics: Animals; Apoptosis; Cell Line; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Endoribonucleases; Glucosides; Humans; Hypoxia; Liver Diseases; Male; MAP Kinase Kinase 4; Multienzyme Complexes; Phenols; Protective Agents; Protein Serine-Threonine Kinases; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Salidroside improves angiogenesis-osteogenesis coupling by regulating the HIF-1α/VEGF signalling pathway in the bone environment.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cellular Microenvironment; Culture Media, Conditioned; Female; Fracture Healing; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Metatarsal Bones; Mice, Inbred BALB C; Neovascularization, Physiologic; Osteoblasts; Osteogenesis; Paracrine Communication; Phenols; Pregnancy; Signal Transduction; Vascular Endothelial Growth Factor A | 2020 |
Dietary supplementation of salidroside increases immune response and disease resistance of crucian carp (Carassius auratus) against Aeromonas hydrophila.
Topics: Aeromonas hydrophila; Animal Feed; Animals; Carps; Diet; Dietary Supplements; Disease Resistance; Dose-Response Relationship, Drug; Fish Diseases; Fish Proteins; Gene Expression Profiling; Gene Expression Regulation; Glucosides; Gram-Negative Bacterial Infections; Immunity, Innate; Phenols; Random Allocation | 2020 |
Variability of Major Phenyletanes and Phenylpropanoids in 16-Year-Old
Topics: Glucosides; Norway; Phenols; Phenylpropionates; Plant Extracts; Plant Roots; Rhizome; Rhodiola | 2020 |
Salidroside inhibits proliferation, migration and invasion of human pancreatic cancer PANC1 and SW1990 cells through the AKT and ERK signaling pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Glucosides; Humans; MAP Kinase Signaling System; Neoplasm Invasiveness; Pancreatic Neoplasms; Phenols; Proto-Oncogene Proteins c-akt; Signal Transduction | 2020 |
Salidroside Ameliorates Mitochondria-Dependent Neuronal Apoptosis after Spinal Cord Ischemia-Reperfusion Injury Partially through Inhibiting Oxidative Stress and Promoting Mitophagy.
Topics: Animals; Apoptosis; Glucosides; Humans; Male; Mice; Mitophagy; Oxidative Stress; Phenols; Reperfusion Injury; Rhodiola; Spinal Cord Ischemia | 2020 |
Transrutinosylation of tyrosol by flower buds of Sophora japonica.
Topics: Flowers; Glucosides; Glycosylation; Phenols; Phenylethyl Alcohol; Rutin; Sophora | 2021 |
Salidroside shows anticonvulsant and neuroprotective effects by activating the Nrf2-ARE pathway in a pentylenetetrazol-kindling epileptic model.
Topics: Animals; Anticonvulsants; Carboxylic Ester Hydrolases; Epilepsy; Glucosides; Hippocampus; Kindling, Neurologic; Male; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Pentylenetetrazole; Phenols; Rats; Rats, Wistar; Signal Transduction | 2020 |
Salidroside inhibits apoptosis and autophagy of cardiomyocyte by regulation of circular RNA hsa_circ_0000064 in cardiac ischemia-reperfusion injury.
Topics: Animals; Apoptosis; Autophagy; Gene Expression Regulation; Glucosides; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Phenols; Plant Extracts; Rats; Rats, Wistar; Reperfusion Injury; Rhodiola; RNA, Circular; Superoxide Dismutase | 2021 |
Salidroside from Rhodiola wallichiana var. cholaensis reverses insulin resistance and stimulates the GLP-1 secretion by alleviating ROS-mediated activation of MAPKs signaling pathway and mitigating apoptosis.
Topics: Apoptosis; Glucagon-Like Peptide 1; Glucosides; Humans; Insulin Resistance; Mitogen-Activated Protein Kinase Kinases; Phenols; Reactive Oxygen Species; Rhodiola; Signal Transduction | 2020 |
Salidroside downregulates microRNA‑133a and inhibits endothelial cell apoptosis induced by oxidized low‑density lipoprotein.
Topics: Apoptosis; bcl-X Protein; Caspase 3; Cells, Cultured; Down-Regulation; Endothelial Cells; Glucosides; Humans; Lipoproteins, LDL; MicroRNAs; Phenols; Rhodiola; Up-Regulation | 2020 |
Rhodiola crenulata reduces ventricular arrhythmia through mitigating the activation of IL-17 and inhibiting the MAPK signaling pathway.
Topics: Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; CD4 Lymphocyte Count; Chemokine CCL20; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Electrocardiography; Glucosides; Inflammation Mediators; Interleukin-17; MAP Kinase Signaling System; NLR Family, Pyrin Domain-Containing 3 Protein; Phenols; Rabbits; Rhodiola; RNA, Messenger; Signal Transduction | 2021 |
Multi-modular engineering of Saccharomyces cerevisiae for high-titre production of tyrosol and salidroside.
Topics: Glucosides; Metabolic Engineering; Phenols; Phenylethyl Alcohol; Saccharomyces cerevisiae | 2021 |
Systems pharmacology unravels the synergic target space and therapeutic potential of Rhodiola rosea L. for non-small cell lung cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Carcinoma, Lewis Lung; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Drug Screening Assays, Antitumor; Flavonoids; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Monosaccharides; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-bcl-2; RAW 264.7 Cells; Rhodiola; Signal Transduction; Transcription Factor RelA | 2020 |
Salidroside can target both P4HB-mediated inflammation and melanogenesis of the skin.
Topics: Adult; Animals; Cell Line, Tumor; Disease Models, Animal; Female; Glucosides; Healthy Volunteers; Humans; Hyperpigmentation; Interferon Regulatory Factor-1; Male; Melanins; Melanocytes; Mice; Molecular Docking Simulation; Monophenol Monooxygenase; Phenols; Procollagen-Proline Dioxygenase; Protein Disulfide-Isomerases; Skin; Skin Aging; Skin Cream; Skin Lightening Preparations; Skin Pigmentation; Transcriptional Activation; Ubiquitination; Ultraviolet Rays; Upstream Stimulatory Factors; Young Adult | 2020 |
Online energy-resolved MS boosts the potential of LC-MS towards metabolite characterization of salidroside and tyrosol.
Topics: Animals; Chromatography, Liquid; Glucosides; Phenols; Phenylethyl Alcohol; Rats; Tandem Mass Spectrometry | 2020 |
[Study on pharmacokinetics and tissue distribution characteristics of salidroside in mice].
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Liquid; Glucosides; Mice; Phenols; Reproducibility of Results; Tandem Mass Spectrometry; Tissue Distribution | 2020 |
[Proteomics analysis of erythrocyte membrane in rats with high altitude polycythemia before and after intervention with salidroside].
Topics: Altitude; Animals; Erythrocytes; Glucosides; Phenols; Polycythemia; Proteomics; Rats; Reproducibility of Results | 2020 |
Inhibition of HMGB1 involved in the protective of salidroside on liver injury in diabetes mice.
Topics: Animals; Anti-Inflammatory Agents; Blood Glucose; Cell Line; Cytokines; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucosides; Hepatitis; HMGB1 Protein; Humans; Hypoglycemic Agents; Liver; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phenols; Receptor for Advanced Glycation End Products; Signal Transduction; Toll-Like Receptor 4 | 2020 |
Inhibitory effects of salidroside on MCF-7 breast cancer cells
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Glucosides; Humans; In Situ Nick-End Labeling; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Phenols; Proto-Oncogene Proteins c-bcl-2; Xenograft Model Antitumor Assays | 2020 |
Salidroside regulates inflammatory pathway of alveolar macrophages by influencing the secretion of miRNA-146a exosomes by lung epithelial cells.
Topics: Acute Lung Injury; Animals; Coculture Techniques; Disease Models, Animal; Epithelial Cells; Exosomes; Glucosides; Inflammation; Macrophages, Alveolar; Male; MicroRNAs; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Salidroside simultaneously reduces de novo lipogenesis and cholesterol biosynthesis to attenuate atherosclerosis in mice.
Topics: 3-Hydroxybutyric Acid; Animals; Anticholesteremic Agents; Atherosclerosis; Cholesterol; Diet, High-Fat; Disease Models, Animal; Fatty Acids; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Glucose; Glucosides; Glycogen; Hypercholesterolemia; Lipidomics; Lipogenesis; Liver; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Phenols; Proton Magnetic Resonance Spectroscopy | 2021 |
Salidroside Inhibits Reactive Astrogliosis and Glial Scar Formation in Late Cerebral Ischemia via the Akt/GSK-3β Pathway.
Topics: Animals; Astrocytes; Brain; Brain Ischemia; Cell Proliferation; Gliosis; Glucosides; Glycogen Synthase Kinase 3 beta; Infarction, Middle Cerebral Artery; Male; Mice, Inbred C57BL; Neuroprotective Agents; Phenols; Proto-Oncogene Proteins c-akt; Signal Transduction | 2021 |
Salidroside protects against cardiomyocyte apoptosis and ventricular remodeling by AKT/HO-1 signaling pathways in a diabetic cardiomyopathy mouse model.
Topics: Animals; Apoptosis; Diabetic Cardiomyopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Heme Oxygenase-1; Male; Mice; Myocytes, Cardiac; Phenols; Proto-Oncogene Proteins c-akt; Signal Transduction; Ventricular Remodeling | 2021 |
Salidroside alleviates diabetic neuropathic pain through regulation of the AMPK-NLRP3 inflammasome axis.
Topics: AMP-Activated Protein Kinases; Analgesics; Animals; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Ganglia, Spinal; Glucosides; Hypoglycemic Agents; Inflammasomes; Insulin Resistance; Male; Neuralgia; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Pain Threshold; Phenols; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Enhanced effects of salidroside on erectile function and corpora cavernosa autophagy in a cavernous nerve injury rat model.
Topics: Animals; Autophagy; Disease Models, Animal; Erectile Dysfunction; Glucosides; Humans; Male; Penile Erection; Penis; Phenols; Rats; Rats, Sprague-Dawley | 2021 |
Salidroside induces cell apoptosis and inhibits the invasiveness of HT29 colorectal cells by regulating protein kinase R, NF-κB and STAT3.
Topics: Apoptosis; Colorectal Neoplasms; eIF-2 Kinase; Glucosides; HT29 Cells; Humans; NF-kappa B; Phenols; Rhodiola; STAT3 Transcription Factor | 2021 |
Disaccahrides-Based Cryo-Formulant Effect on Modulating Phospho/Mitochondrial Lipids and Biological Profiles of Human Leukaemia Cells.
Topics: Cardiolipins; Cell Survival; Cryopreservation; Dimethyl Sulfoxide; Disaccharides; Glucosides; HL-60 Cells; Humans; Leukemia; Lipid Peroxidation; Mitochondria; Oxidation-Reduction; Phenols | 2021 |
Salidroside protects endothelial cells against LPS-induced inflammatory injury by inhibiting NLRP3 and enhancing autophagy.
Topics: Apoptosis; Autophagy; Cells, Cultured; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Inflammasomes; Inflammation; NLR Family, Pyrin Domain-Containing 3 Protein; Phenols; Signal Transduction | 2021 |
Salidroside protects cardiac function in mice with diabetic cardiomyopathy via activation of mitochondrial biogenesis and SIRT3.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Glucosides; Mice; Mitochondria; Myocytes, Cardiac; Organelle Biogenesis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phenols; Rats; Sirtuin 3 | 2021 |
The bioinformatics and metabolomics research on anti-hypoxic molecular mechanisms of Salidroside via regulating the PTEN mediated PI3K/Akt/NF-κB signaling pathway.
Topics: Animals; Cell Hypoxia; Computational Biology; Glucosides; Metabolomics; NF-kappa B; PC12 Cells; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Signal Transduction | 2021 |
Protective Effect of Salidroside on Mitochondrial Disturbances via Reducing Mitophagy and Preserving Mitochondrial Morphology in OGD-induced Neuronal Injury.
Topics: Animals; Brain Ischemia; Cell Line; Cell Survival; Glucose; Glucosides; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitophagy; Neurons; Neuroprotective Agents; Oxygen; Phenols; Reactive Oxygen Species | 2021 |
Salidroside Prevents Hypoxia-Induced Human Retinal Microvascular Endothelial Cell Damage Via miR-138/ROBO4 Axis.
Topics: Blotting, Western; Endothelium, Vascular; Flow Cytometry; Gene Expression Regulation; Glucosides; Humans; Hypoxia; Male; MicroRNAs; Phenols; Retinal Diseases; Retinal Vessels | 2021 |
Salidroside promoted osteogenic differentiation of adipose-derived stromal cells through Wnt/β-catenin signaling pathway.
Topics: Adipose Tissue; beta Catenin; Cell Differentiation; Cells, Cultured; Glucosides; Humans; Osteogenesis; Phenols; Stromal Cells; Wnt Signaling Pathway | 2021 |
Salidroside Activates the AMP-Activated Protein Kinase Pathway to Suppress Nonalcoholic Steatohepatitis in Mice.
Topics: AMP-Activated Protein Kinases; Animals; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Glucosides; Hepatocytes; Humans; Liver; Male; Mice; Non-alcoholic Fatty Liver Disease; Phenols; Primary Cell Culture; Signal Transduction | 2021 |
[Study on mechanism of salidroside against liver fibrosis by regulating CXCL16].
Topics: Animals; Carbon Tetrachloride; Chemokine CXCL16; Glucosides; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Male; Mice; Phenols | 2021 |
Salidroside attenuates acute lung injury via inhibition of inflammatory cytokine production.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Cell Line; Cytokines; Gene Expression; Glucosides; Granulocyte-Macrophage Colony-Stimulating Factor; Inflammation; Interleukin-6; Lipopolysaccharides; Macrophages, Alveolar; Male; Phenols; Rats, Sprague-Dawley; Rhodiola; Tumor Necrosis Factor-alpha | 2021 |
Salidroside inhibits endothelial‑mesenchymal transition via the KLF4/eNOS signaling pathway.
Topics: Atherosclerosis; Cell Line; Cell Movement; Down-Regulation; Endothelial Cells; Glucosides; Humans; Kruppel-Like Factor 4; Nitric Oxide; Nitric Oxide Synthase Type III; Phenols; RNA, Small Interfering; Signal Transduction | 2021 |
Neuroprotective effects of salidroside on ageing hippocampal neurons and naturally ageing mice via the PI3K/Akt/TERT pathway.
Topics: Aging; Animals; Glucosides; Hippocampus; Mice; Neurons; Neuroprotective Agents; Phenols; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats | 2021 |
Inhibition of hypoxia-inducible factor-1 by salidroside in an
Topics: Choroidal Neovascularization; Glucosides; Humans; Hypoxia; Hypoxia-Inducible Factor 1; Phenols; Vascular Endothelial Growth Factor A | 2022 |
Salidroside alleviates taurolithocholic acid 3-sulfate-induced AR42J cell injury.
Topics: Animals; Autophagy; Cell Line; Cell Survival; Glucosides; Inflammation; NF-kappa B; Pancreas; Pancreatitis; Phenols; Rats; Signal Transduction; Taurolithocholic Acid | 2021 |
Salidroside alleviates liver inflammation in furan-induced mice by regulating oxidative stress and endoplasmic reticulum stress.
Topics: Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Furans; Glucosides; Inflammation; Liver; Male; Metabolomics; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Phenols | 2021 |
Salidroside Suppresses the Proliferation and Migration of Human Lung Cancer Cells through AMPK-Dependent NLRP3 Inflammasome Regulation.
Topics: AMP-Activated Protein Kinases; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; Glucosides; Humans; Inflammasomes; Lipopolysaccharides; Lung Neoplasms; NLR Family, Pyrin Domain-Containing 3 Protein; Phenols; Reactive Oxygen Species; Signal Transduction; Tumor Cells, Cultured | 2021 |
Salidroside attenuates cardiac dysfunction in a rat model of diabetes.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Diabetic Cardiomyopathies; Disease Models, Animal; Glucosides; Inflammation; Male; Myocytes, Cardiac; Oxidative Stress; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; TOR Serine-Threonine Kinases | 2022 |
Salidroside Induces Apoptosis in Human Gastric Cancer Cells via the Downregulation of ENO1/PKM2/GLUT1 Expression.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Down-Regulation; Glucose Transporter Type 1; Glucosides; Glycolysis; Humans; Membrane Proteins; Mice, Inbred BALB C; Mice, Nude; Phenols; Phosphopyruvate Hydratase; Phytotherapy; Plant Extracts; Rhodiola; Stomach Neoplasms; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2021 |
Multiple mechanisms of salidroside on anti-tumor effects.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Differentiation; Glucosides; Humans; Neoplasms; Phenols; Signal Transduction | 2021 |
Salidroside-pretreated mesenchymal stem cells contribute to neuroprotection in cerebral ischemic injury in vitro and in vivo.
Topics: Animals; Apoptosis; Biomarkers; Brain Ischemia; CA1 Region, Hippocampal; Cell Survival; Cells, Cultured; Disease Management; Disease Models, Animal; Fluorescent Antibody Technique; Glucosides; Immunohistochemistry; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Neuroprotection; Phenols; Rats | 2021 |
Discovery of Glycosyltransferases Involved in the Biosynthesis of Ligupurpuroside B.
Topics: Bacterial Proteins; Glucosides; Glycosides; Glycosyltransferases; Hexosyltransferases; Molecular Structure; Phenols; Phenylethyl Alcohol | 2021 |
Salidroside Alleviates Chronic Constriction Injury-Induced Neuropathic Pain and Inhibits of TXNIP/NLRP3 Pathway.
Topics: Animals; Carrier Proteins; Cell Cycle Proteins; Constriction; Glucosides; Inflammasomes; Mice; Neuralgia; NLR Family, Pyrin Domain-Containing 3 Protein; NLR Proteins; Phenols; Rats; Rats, Sprague-Dawley; Thioredoxins | 2022 |
Salidroside orchestrates metabolic reprogramming by regulating the Hif-1α signalling pathway in acute mountain sickness.
Topics: Acute Disease; Altitude Sickness; Animals; Brain; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Mice, Inbred C57BL; PC12 Cells; Phenols; Rats; Rhodiola; Signal Transduction | 2021 |
Salidroside alleviates oxidative stress and apoptosis via AMPK/Nrf2 pathway in DHT-induced human granulosa cell line KGN.
Topics: AMP-Activated Protein Kinases; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Nucleus; Dihydrotestosterone; Gene Knockdown Techniques; Glucosides; Humans; NF-E2-Related Factor 2; Oxidative Stress; Phenols; Signal Transduction | 2022 |
Uncovering the Metabolic Mechanism of Salidroside Alleviating Microglial Hypoxia Inflammation Based on Microfluidic Chip-Mass Spectrometry.
Topics: Glucosides; Humans; Hypoxia; Inflammation; Lipopolysaccharides; Mass Spectrometry; Microfluidics; Microglia; NF-kappa B; Phenols; Signal Transduction | 2022 |
Salidroside Attenuates Airway Inflammation and Remodeling via the miR-323-3p/SOCS5 Axis in Asthmatic Mice.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Glucosides; Inflammation; Lung; Mice; Mice, Inbred BALB C; MicroRNAs; Ovalbumin; Phenols; Signal Transduction; Suppressor of Cytokine Signaling Proteins | 2022 |
Insight into the Protective Effect of Salidroside against H
Topics: Animals; Apoptosis; Cell Line; Down-Regulation; Glucosides; Hydrogen Peroxide; Myocytes, Cardiac; Phenols; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Superoxide Dismutase; Tumor Suppressor Protein p53; Up-Regulation | 2021 |
Discovery of Salidroside-Derivated Glycoside Analogues as Novel Angiogenesis Agents to Treat Diabetic Hind Limb Ischemia.
Topics: Angiogenesis Inducing Agents; Animals; Diabetes Mellitus, Experimental; Glucosides; Glycosides; Hindlimb; Ischemia; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Phenols; Rats; Rats, Sprague-Dawley | 2022 |
Salidroside Promotes Sensitization to Doxorubicin in Human Cancer Cells by Affecting the PI3K/Akt/HIF Signal Pathway and Inhibiting the Expression of Tumor-Resistance-Related Proteins.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; Glucosides; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2022 |
Salidroside prevents PM2.5-induced BEAS-2B cell apoptosis via SIRT1-dependent regulation of ROS and mitochondrial function.
Topics: Apoptosis; Glucosides; Mitochondria; Particulate Matter; Phenols; Reactive Oxygen Species; Sirtuin 1 | 2022 |
Salidroside suppresses the activation of nasopharyngeal carcinoma cells via targeting miR-4262/GRP78 axis.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Endoplasmic Reticulum Chaperone BiP; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Mice; Mice, Nude; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Phenols | 2022 |
Salidroside, 8(
Topics: Fibrosarcoma; Fruit; Glucosides; Humans; Ligustrum; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Phenols; Pyrans; Tetradecanoylphorbol Acetate | 2022 |
[Salidroside inhibits phenotypic transformation of rat pulmonary artery smooth muscle cells induced by hypoxia].
Topics: Animals; Cell Proliferation; Cells, Cultured; Glucosides; Hypoxia; Myocytes, Smooth Muscle; Phenols; Pulmonary Artery; Rats | 2022 |
Therapeutic effects of salidroside vs pyrrolidine dithiocarbamate against severe acute pancreatitis in rat.
Topics: Acute Disease; Animals; Glucosides; Humans; Interleukin-10; NF-kappa B; Pancreatitis; Phenols; Pyrrolidines; Rats; Rats, Sprague-Dawley; Thiocarbamates; Transcription Factors; Tumor Necrosis Factor-alpha | 2022 |
Long-Term Oral Administration of Salidroside Alleviates Diabetic Retinopathy in db/db Mice.
Topics: Administration, Oral; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glucosides; Mice; Phenols | 2022 |
Salidroside Protects Acute Kidney Injury in Septic Rats by Inhibiting Inflammation and Apoptosis.
Topics: Acute Kidney Injury; Animals; Apoptosis; Glucosides; Inflammation; Kidney; NF-kappa B; Phenols; Rats; RNA, Messenger; Sepsis | 2022 |
Salidroside, a phenyl ethanol glycoside from Rhodiola crenulata, orchestrates hypoxic mitochondrial dynamics homeostasis by stimulating Sirt1/p53/Drp1 signaling.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Brain Injuries; Glucosides; Glycosides; Homeostasis; Hypoxia; Mitochondrial Dynamics; Molecular Docking Simulation; Phenols; Phenylethyl Alcohol; Rhodiola; Signal Transduction; Sirtuin 1; Superoxide Dismutase; Tumor Suppressor Protein p53 | 2022 |
Salidroside Ameliorates Ischemia-Induced Neuronal Injury through AMPK Dependent and Independent Pathways to Maintain Mitochondrial Quality Control.
Topics: AMP-Activated Protein Kinases; Animals; Brain Ischemia; Calcium; Glucose; Glucosides; Ischemia; Mice; Mitochondria; Neurons; Phenols | 2022 |
Salidroside attenuates high altitude hypobaric hypoxia-induced brain injury in mice via inhibiting NF-κB/NLRP3 pathway.
Topics: Adenosine Triphosphatases; Altitude; Animals; Brain Injuries; Glucosides; Hypoxia; Mice; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phenols | 2022 |
Salidroside alleviates cadmium-induced toxicity in mice by restoring the notch/HES-1 and RIP1-driven inflammatory signaling axis.
Topics: Animals; Antioxidants; Cadmium; Glucosides; Mice; Phenols; Rhodiola; Signal Transduction | 2022 |
Salidroside Exerts Beneficial Effect on Testicular Ischemia-Reperfusion Injury in Rats.
Topics: Animals; Antioxidants; Catalase; Glucosides; Ischemia; Male; Malondialdehyde; Phenols; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Spermatic Cord Torsion; Superoxide Dismutase; Testis | 2022 |
Salidroside attenuates myocardial ischemia/reperfusion injury via AMPK-induced suppression of endoplasmic reticulum stress and mitochondrial fission.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Endoplasmic Reticulum Stress; Glucosides; Mitochondrial Dynamics; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phenols; Rats; RNA, Small Interfering | 2022 |
Engineered Red Blood Cell Membrane-Coating Salidroside/Indocyanine Green Nanovesicles for High-Efficiency Hypoxic Targeting Phototherapy of Triple-Negative Breast Cancer.
Topics: Cell Line, Tumor; Erythrocyte Membrane; Glucosides; Humans; Hypoxia; Indocyanine Green; Nanoparticles; Phenols; Photochemotherapy; Phototherapy; Triple Negative Breast Neoplasms | 2022 |
Salidroside ameliorates orthopedic surgery-induced cognitive dysfunction by activating adenosine 5'-monophosphate-activated protein kinase signaling in mice.
Topics: Adenosine; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Cognitive Dysfunction; Glucosides; Mice; Mice, Inbred C57BL; Microglia; Molecular Docking Simulation; Orthopedic Procedures; Phenols | 2022 |
[Protective effect of salidroside on high fat-induced apoptosis in H9c2 cardiomyocytes through AMPK/mTOR/p70S6K pathway].
Topics: AMP-Activated Protein Kinases; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Glucosides; Myocytes, Cardiac; Phenols; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Messenger; TOR Serine-Threonine Kinases | 2022 |
The Combination of Rhodosin and MMF Prolongs Cardiac Allograft Survival by Inhibiting DC Maturation by Promoting Mitochondrial Fusion.
Topics: Allografts; Animals; Antioxidants; Glucosides; Graft Rejection; Graft Survival; Immunosuppressive Agents; Kidney Transplantation; Mice; Mitochondrial Dynamics; Mycophenolic Acid; Phenols | 2022 |
Dietary supplementation of salidroside alleviates liver lipid metabolism disorder and inflammatory response to promote hepatocyte regeneration via PI3K/AKT/Gsk3-β pathway.
Topics: Abnormalities, Multiple; Animals; Body Weight; Chickens; Craniofacial Abnormalities; Diet, High-Fat; Dietary Supplements; Fatty Liver; Female; Glucosides; Glycogen Synthase Kinase 3; Growth Disorders; Heart Septal Defects, Ventricular; Hepatocytes; Lipid Metabolism; Lipid Metabolism Disorders; Liver; Phenols; Phosphatidylinositol 3-Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt; RNA, Messenger; Triglycerides | 2022 |
Modulation of Disordered Bile Acid Homeostasis and Hepatic Tight Junctions Using Salidroside against Hepatocyte Apoptosis in Furan-Induced Mice.
Topics: Animals; Apoptosis; Bile Acids and Salts; Furans; Glucosides; Hepatocytes; Homeostasis; Liver; Mice; Mice, Inbred BALB C; Phenols; Tight Junctions | 2022 |
Salidroside alleviates severe acute pancreatitis-triggered pancreatic injury and inflammation by regulating miR-217-5p/YAF2 axis.
Topics: Acute Disease; Animals; Apoptosis; Glucosides; Inflammation; MicroRNAs; Muscle Proteins; Pancreatitis; Phenols; Rats; Repressor Proteins | 2022 |
Salidroside alleviates hepatic ischemia-reperfusion injury during liver transplant in rat through regulating TLR-4/NF-κB/NLRP3 inflammatory pathway.
Topics: Animals; Anti-Inflammatory Agents; Glucosides; Interleukin-18; Liver; Liver Transplantation; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phenols; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2022 |
Salidroside attenuates sepsis-associated acute lung injury through PPP1R15A mediated endoplasmic reticulum stress inhibition.
Topics: Acute Lung Injury; Animals; Endoplasmic Reticulum Stress; Glucosides; Lipopolysaccharides; Lung; Phenols; Rats; Sepsis | 2022 |
Salidroside improves porcine oocyte maturation and subsequent embryonic development by promoting lipid metabolism.
Topics: Animals; Blastocyst; Embryonic Development; Glucosides; In Vitro Oocyte Maturation Techniques; Lipid Metabolism; Lipids; Mammals; Oocytes; Phenols; Reactive Oxygen Species; Swine | 2022 |
Protective effect of salidroside on streptozotocin-induced diabetic nephropathy by inhibiting oxidative stress and inflammation in rats via the Akt/GSK-3β signalling pathway.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glucosides; Glycogen Synthase Kinase 3 beta; Inflammation; Male; Oxidative Stress; Phenols; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Streptozocin | 2022 |
Rhodiola activates macrophage migration inhibitory factor to alleviate non-alcoholic fatty liver disease.
Topics: Animals; Blood Glucose; Diet, High-Fat; Glucosides; Insulin; Lipid Metabolism; Liver; Macrophage Migration-Inhibitory Factors; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Palmitates; Phenols; Plant Extracts; Rhodiola; RNA, Small Interfering; Saline Solution; Triglycerides | 2022 |
Gut microbiota profiling revealed the regulating effects of salidroside on iron metabolism in diabetic mice.
Topics: Animals; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Gastrointestinal Microbiome; Glucosides; Iron; Mice; Phenols; RNA, Ribosomal, 16S | 2022 |
Antihypothyroid Effect of Salidroside.
Topics: Glucosides; Humans; Hypothyroidism; Plant Extracts; Rhodiola | 2022 |
Mechanism of salidroside in the treatment of chronic myeloid leukemia based on the network pharmacology and molecular docking.
Topics: Drugs, Chinese Herbal; Glucosides; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Docking Simulation; Network Pharmacology | 2023 |
Salidroside Alleviates Renal Fibrosis in SAMP8 Mice by Inhibiting Ferroptosis.
Topics: Animals; Ferroptosis; Fibrosis; Glucosides; Kidney Diseases; Mice | 2022 |
Qualitative and Quantitative Evaluation of Rosavin, Salidroside, and p-Tyrosol in Artic Root Products via TLC-Screening, HPLC-DAD, and NMR Spectroscopy.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Glucosides; Magnetic Resonance Spectroscopy | 2022 |
Complete biosynthesis of the phenylethanoid glycoside verbascoside.
Topics: Glucosides; Glycosides; Phenols | 2023 |
Reshaped Gut Microbial Composition and Functions Associated with the Antifatigue Effect of Salidroside in Exercise Mice.
Topics: Animals; Gastrointestinal Microbiome; Glucosides; Mice; Phenols; Plant Extracts | 2023 |
Molecular Identification of UDP-Sugar-Dependent Glycosyltransferase and Acyltransferase Involved in the Phenylethanoid Glycoside Biosynthesis Induced by Methyl Jasmonate in Sesamum indicum L.
Topics: Glucose; Glucosides; Glucosyltransferases; Glycosides; Glycosyltransferases; Phylogeny; Recombinant Proteins; Sesamum; Sugars; Uridine Diphosphate | 2023 |
Salidroside attenuates LPS-induced inflammatory activation in young rats with acute lung injury via PI3K/Akt signaling pathway.
Topics: Acute Lung Injury; Animals; Glucosides; Lipopolysaccharides; Lung; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Necrosis Factor-alpha | 2023 |
Mechanism of salidroside against coronary artery disease by network pharmacology analysis.
Topics: Coronary Artery Disease; Glucosides; Humans; Network Pharmacology; Phenols | 2023 |
Salidroside suppresses the multiple oncogenic activates and immune escape of lung adenocarcinoma through the circ_0009624-mediated PD-L1 pathway.
Topics: Adenocarcinoma of Lung; B7-H1 Antigen; Cell Line, Tumor; Cell Proliferation; Glucosides; Humans; Lung Neoplasms | 2023 |
Salidroside affects the Th17/Treg cell balance in aplastic anemia via the STAT3/HIF-1α/RORγt pathway.
Topics: Anemia, Aplastic; Animals; Glucosides; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Nuclear Receptor Subfamily 1, Group F, Member 3; STAT3 Transcription Factor; T-Lymphocytes, Regulatory; Th17 Cells | 2023 |
Topics: Animals; Cytochrome P-450 Enzyme System; Drug Interactions; Glucosides; HEK293 Cells; Rabbits; Rats | 2023 |
Effects and mechanisms of salidroside on the behavior of SPS-induced PTSD rats.
Topics: Animals; Disease Models, Animal; Glucosides; Hippocampus; Humans; Phenols; Rats; Stress Disorders, Post-Traumatic | 2023 |