rhodinose and grincamycin

rhodinose has been researched along with grincamycin* in 1 studies

Other Studies

1 other study(ies) available for rhodinose and grincamycin

Article	Year
Identification of the grincamycin gene cluster unveils divergent roles for GcnQ in different hosts, tailoring the L-rhodinose moiety. Organic letters, 2013, Jul-05, Volume: 15, Issue:13 The gene cluster responsible for grincamycin (GCN, 1) biosynthesis in Streptomyces lusitanus SCSIO LR32 was identified; heterologous expression of the GCN cluster in S. coelicolor M512 yielded P-1894B (1b) as a predominant product. The ΔgcnQ mutant accumulates intermediate 1a and two shunt products 2a and 3a bearing L-rhodinose for L-cinerulose A substitutions. In vitro data demonstrated that GcnQ is capable of iteratively tailoring the two L-rhodinose moieties into L-aculose moieties, supporting divergent roles of GcnQ in different hosts. Topics: Anthraquinones; Benz(a)Anthracenes; Cloning, Molecular; Molecular Sequence Data; Molecular Structure; Monosaccharides; Multigene Family; Nuclear Magnetic Resonance, Biomolecular; Streptomyces coelicolor	2013

Article

Year

Identification of the grincamycin gene cluster unveils divergent roles for GcnQ in different hosts, tailoring the L-rhodinose moiety.

Organic letters, 2013, Jul-05, Volume: 15, Issue:13

The gene cluster responsible for grincamycin (GCN, 1) biosynthesis in Streptomyces lusitanus SCSIO LR32 was identified; heterologous expression of the GCN cluster in S. coelicolor M512 yielded P-1894B (1b) as a predominant product. The ΔgcnQ mutant accumulates intermediate 1a and two shunt products 2a and 3a bearing L-rhodinose for L-cinerulose A substitutions. In vitro data demonstrated that GcnQ is capable of iteratively tailoring the two L-rhodinose moieties into L-aculose moieties, supporting divergent roles of GcnQ in different hosts.

Topics: Anthraquinones; Benz(a)Anthracenes; Cloning, Molecular; Molecular Sequence Data; Molecular Structure; Monosaccharides; Multigene Family; Nuclear Magnetic Resonance, Biomolecular; Streptomyces coelicolor

2013