rhodanine has been researched along with naphthalene* in 1 studies
1 other study(ies) available for rhodanine and naphthalene
Article | Year |
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Synthesis and biological evaluation of rhodanine derivatives as PRL-3 inhibitors.
A series of rhodanine derivatives was synthesized and evaluated for their ability to inhibit PRL-3. Benzylidene rhodanine derivative showed good biological activity, while compound 5e was the most active in this series exhibiting an IC50 value of 0.9 microM in vitro and showed a reduced invasion in cell-based assay. Topics: Aldehydes; Animals; Cell Line, Tumor; Enzyme Inhibitors; Humans; Mice; Molecular Structure; Naphthalenes; Protein Binding; Protein Tyrosine Phosphatases; Rhodanine; Structure-Activity Relationship | 2006 |