rhodanine has been researched along with hippuric-acid* in 1 studies
1 other study(ies) available for rhodanine and hippuric-acid
Article | Year |
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In vitro studies of potent aldose reductase inhibitors: Synthesis, characterization, biological evaluation and docking analysis of rhodanine-3-hippuric acid derivatives.
Inhibitors of aldose reductase are rate-limiting enzymes and could play a key role to prevent the complications of diabetes. In our attempt to develop novel inhibitors of aldose reductase, the derivatives of rhodanine-3-hippuric acid-pyrazole hybrid were synthesized and characterised by spectral data. The biological studies reveal that all the compounds show an excellent activity against ALR2 with IC Topics: Aldehyde Reductase; Drug Design; Drug Discovery; Enzyme Inhibitors; Hippurates; Humans; Molecular Docking Simulation; Rhodanine; Structure-Activity Relationship | 2020 |