rhodamine 123 has been researched along with paclitaxel in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (10.71) | 18.2507 |
| 2000's | 24 (42.86) | 29.6817 |
| 2010's | 25 (44.64) | 24.3611 |
| 2020's | 1 (1.79) | 2.80 |
| Authors | Studies |
|---|---|
| Cescon, DW; Hansen, MD; Hoj, JP; Siddiqui-Jain, A | 1 |
| Chute, SK; Durham, SK; Flint, OP | 1 |
| Brouty-Boyé, D; Kolonias, D; Lampidis, TJ; Savaraj, N; Wu, CJ | 1 |
| Alken, P; Köhrmann, KU; Kreukler, C; Nebe, T; Siegsmund, MJ; Steidler, A | 1 |
| Méndez-Vidal, C; Quesada, AR | 1 |
| Chi, CW; Lin, HL; Liu, TY; Wu, CW | 1 |
| Dintaman, JM; Silverman, JA | 1 |
| Berridge, G; Callaghan, R; Charlton, P; Higgins, CF; Martin, C; Mistry, P | 1 |
| Beketic-Oreskovic, L; Chen, GK; Durán, GE; Mangili, A; Sikic, BI | 1 |
| Audus, KL; Backstrom, G; Hamilton, KO; Yazdanian, MA | 1 |
| Appert, HE; Howard, JM; Iwamura, T; Liu, B; Staren, ED | 1 |
| Casciano, CN; Clement, RP; Johnson, WW; Wang, E | 1 |
| Appert, H; Howard, J; Iwamura, T; Liu, B; Staren, E | 1 |
| Ohnishi, N; Takara, K; Tsujimoto, M; Yokoyama, T | 1 |
| Audus, KL; Georg, G; Liu, Y; Michaelis, ML; Rice, A; Turunen, B | 1 |
| Callaghan, R; Martin, C; Rothnie, A; Walker, J | 1 |
| Drinyaev, VA; Ermakova, NV; Korystov, YN; Kruglyak, EB; Kublik, LN; Levitman, MKh; Mosin, VA; Novik, TS; Shaposhnikova, VV; Sterlina, TS | 1 |
| Audus, KL; Georg, GI; Himes, RH; Liu, Y; Michaelis, ML; Rice, A | 1 |
| Gäbel, G; Honscha, KU; Honscha, W; Kneuer, C | 1 |
| Emel'yanov, MO; Korystov, YN; Korystova, AF; Kublik, LN; Shaposhnikova, VV | 1 |
| He, Y; Shen, S; Zeng, S | 1 |
| Katayama, K; Mitsuhashi, J; Sugimoto, Y; Tsukahara, S; Yoshioka, S | 1 |
| Dong, P; Jiang, AC; Li, L; Wan, Y; Yu, ZW | 1 |
| Ambudkar, SV; Barnett, D; Bates, SE; Finley, EM; Fojo, T; Oldham, RK; Robey, RW; Shukla, S | 1 |
| Choi, WS; Han, JW; Hwang, JW; Kim, NH; Kim, SN; Kim, YK; Lee, HY; Park, YS; Seo, DW; Song, YJ | 1 |
| Chang, YW; Chao, YS; Chen, CT; Chiang, TH; Ho, PY; Lin, HL; Lo, YK; Wu, HY; Wu, SH; Yao, HT; Yeh, TK | 1 |
| Ahn, KS; Bae, HS; Choi, SU; Choi, WC; Kang, JM; Kim, MO; Kim, SH; Koo, JS; Lee, EO; Lee, HJ; Lu, J; Rhee, YH | 1 |
| Chmielewski, J; Emmert, D; Hrycyna, CA; Pires, MM | 1 |
| Kawami, M; Nagai, J; Otani, Y; Takano, M; Tanda, M; Yumoto, R | 1 |
| Chen, X; Dai, J; Li, H; Li, Y; Qu, R; Su, F; Wang, H; Yin, D; Zhang, Y | 1 |
| Junyaprasert, VB; Kawami, M; Nagai, J; Patanasethanont, D; Soonthornchareonnon, N; Sripanidkulchai, BO; Takano, M; Yumoto, R | 1 |
| Fodor, Z; Galuska, L; Goda, K; Hernádi, Z; Krasznai, ZT; Mikecz, P; Szabó, G; Tóth, A | 1 |
| Ambudkar, SV; Limtrakul, P; Ohnuma, S; Pintha, K; Pitchakarn, P; Pompimon, W | 1 |
| Mongayt, D; Patel, NR; Rathi, A; Torchilin, VP | 1 |
| Andelković, T; Banković, J; Pešić, M; Podolski-Renić, A; Ruždijić, S; Tanić, N | 1 |
| Chen, L; Deng, Y; Gao, Y; Ji, X; Li, Y; Zhang, Z | 1 |
| Cheng, C; Fu, LW; Huang, HB; Liang, YJ; To, KK; Wang, F; Wang, XK; Zhang, X; Zhou, W; Zhou, WJ | 1 |
| Geldenhuys, WJ; Oyewumi, MO; Wehrung, D | 1 |
| Barnett, D; Bates, SE; Caluag, Z; Chen, CC; Draper, D; Fojo, T; Frye, AR; Kelly, RJ; Luchenko, V; Oldham, RK; Robey, RW; Steinberg, SM | 1 |
| Geckeler, KE; Lee, Y | 1 |
| Fang, X; Hao, J; Wei, Z; Yuan, S | 1 |
| Chen, WM; Chen, ZS; Fu, LW; Fung, KP; Lan, P; Li, YJ; Peng, YH; Ruan, ZX; Shu, C; Wang, J; Yao, Z; Ye, WC; Yiu, A; Zhang, DM | 1 |
| Fu, Q; Liu, F; Racette, K; Ramishetti, S; Tang, J; Wang, D; Wang, Y | 1 |
| Duan, L; Huo, QL; Li, GF; Ren, F; Sun, YB; Wang, SQ; Zhao, BX | 1 |
| Fan, H; Fawcett, JP; Gu, J; Guo, Y; Liu, J; Ma, W; Sun, Y; Wang, T; Yang, J; Yang, Y; Yang, Z | 1 |
| Huang, W; Jiao, L; Li, Y; Liu, B; Qian, H; Qiu, Q; Zhao, T | 1 |
| Chen, S; Li, X; Liu, M; Shi, Q; Xu, X; Zhang, J; Zhang, L; Zhang, X | 1 |
| Feng, S; Liu, L; Ma, W; Xie, Y; Yao, X; Yuan, Z | 1 |
| Callaghan, R; George, AM; Kerr, ID; Mittra, R; O'Mara, ML; Pavy, M; Subramanian, N | 1 |
| Chen, M; Chen, S; Fai Chan, H; He, C; Wang, L; Wang, Y; Xie, W; Zhang, J | 1 |
| Cai, H; Chen, Q; Fu, Y; Huo, M; Mu, Y; Xu, W; Yao, L; Yin, T; Yu, Y; Zhou, J | 1 |
| Edaki, K; Kamioka, H; Kasahara, H; Ogihara, T; Tomono, T; Yano, K | 1 |
| An, SH; Guo, QM; Jiang, YQ; Liu, QY; Su, F; Tai, JB; Xu, JL; Xu, XC; Xu, XP | 1 |
| Hargrove, P; Kim, RB; Lan, LB; Lecureur, V; Schuetz, EG; Schuetz, JD; Sun, D | 1 |
| Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
2 trial(s) available for rhodamine 123 and paclitaxel
| Article | Year |
|---|---|
Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R)).
Topics: Adenosine Triphosphatases; Alkaloids; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Factors; Biological Transport; Cell Line; Cell Line, Tumor; Cyclosporins; Depsipeptides; Fluorescent Dyes; Fluorouracil; Humans; Insecta; Multidrug Resistance-Associated Proteins; Neoplasms; Paclitaxel; Prazosin; Quinolines; Rhodamine 123; Verapamil; Vinblastine | 2008 |
A pharmacodynamic study of the P-glycoprotein antagonist CBT-1® in combination with paclitaxel in solid tumors.
Topics: Abdominal Neoplasms; Adult; Aged; Alkaloids; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Interactions; Female; Humans; Leukocytes, Mononuclear; Liver; Male; Middle Aged; Paclitaxel; Radiopharmaceuticals; Rhodamine 123; Technetium Tc 99m Sestamibi | 2012 |
54 other study(ies) available for rhodamine 123 and paclitaxel
| Article | Year |
|---|---|
Pharmacology and in vivo efficacy of pyridine-pyrimidine amides that inhibit microtubule polymerization.
Topics: Amides; Animals; Cell Line, Tumor; Cell Proliferation; Dogs; Dose-Response Relationship, Drug; Humans; Mice; Microsomes, Liver; Microtubules; Molecular Structure; Neoplasms, Experimental; Polymerization; Pyridines; Pyrimidines; Rats; Structure-Activity Relationship | 2018 |
Analysis of the steady-state dynamics of organelle motion in cultured neurites: putative indicator of neurotoxic effect.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents, Phytogenic; Calcium; Cells, Cultured; Flow Cytometry; Fluorescent Dyes; Lasers; Magnesium; Mesencephalon; Microtubules; Mitochondria; Neurites; Neurotoxins; Paclitaxel; Rats; Rhodamine 123; Rhodamines; Vinblastine | 1995 |
Relationship of multidrug resistance to rhodamine-123 selectivity between carcinoma and normal epithelial cells: taxol and vinblastine modulate drug efflux.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Breast; Breast Neoplasms; Cell Line; Cell Survival; DNA Primers; Drug Resistance, Multiple; Epithelial Cells; Epithelium; Female; Gene Expression; Humans; Molecular Sequence Data; Paclitaxel; Polymerase Chain Reaction; Rhodamine 123; Rhodamines; Tumor Cells, Cultured; Vinblastine | 1995 |
Multidrug resistance in androgen-independent growing rat prostate carcinoma cells is mediated by P-glycoprotein.
Topics: Androgens; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Fluorescent Dyes; Genes, MDR; Male; Methotrexate; Neoplasms, Hormone-Dependent; Paclitaxel; Prostatic Neoplasms; Rats; Rhodamine 123; Rhodamines; Tumor Cells, Cultured; Verapamil; Vinblastine | 1997 |
Reversal of P-glycoprotein-mediated multidrug resistance in vitro by AV200, a new ardeemin derivative.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Heterocyclic Compounds, 3-Ring; Humans; Paclitaxel; Rhodamine 123; Tumor Cells, Cultured; Verapamil; Vincristine | 1998 |
Berberine modulates expression of mdr1 gene product and the responses of digestive track cancer cells to Paclitaxel.
Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Berberine; Carcinoma; Cell Cycle; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorescent Dyes; Genes, MDR; Growth Inhibitors; Humans; Mice; Mouth Neoplasms; Paclitaxel; Rhodamine 123; Stomach Neoplasms; Tumor Cells, Cultured | 1999 |
Inhibition of P-glycoprotein by D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS).
Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Survival; Coloring Agents; Cyclosporine; Fluorouracil; Immunosuppressive Agents; Mice; Micelles; Paclitaxel; Polyethylene Glycols; Rhodamine 123; Vinblastine; Vitamin E | 1999 |
Communication between multiple drug binding sites on P-glycoprotein.
Topics: Acridines; Allosteric Regulation; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Benzylidene Compounds; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Drug Interactions; Isoquinolines; Kinetics; Nicardipine; Paclitaxel; Quinolines; Radioligand Assay; Radiopharmaceuticals; Rhodamine 123; Tetrahydroisoquinolines; Tritium; Vinblastine | 2000 |
MDR 1 activation is the predominant resistance mechanism selected by vinblastine in MES-SA cells.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cyclosporins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Female; Gene Expression Regulation, Neoplastic; Genes, MDR; Humans; Multidrug Resistance-Associated Proteins; Mutation; Neoplasm Proteins; Paclitaxel; Phenotype; Rhodamine 123; RNA, Messenger; Sarcoma; Tritium; Tumor Cells, Cultured; Uterine Neoplasms; Vault Ribonucleoprotein Particles; Vinblastine | 2000 |
P-glycoprotein efflux pump expression and activity in Calu-3 cells.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Caco-2 Cells; Cell Line; Cyclosporine; Enzyme Inhibitors; Fluorescent Dyes; Humans; Multidrug Resistance-Associated Proteins; Paclitaxel; Rhodamine 123; Vinblastine | 2001 |
Mechanisms of taxotere-related drug resistance in pancreatic carcinoma.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Docetaxel; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorescent Dyes; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Indomethacin; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Paclitaxel; Pancreatic Neoplasms; Rhodamine 123; RNA, Messenger; Taxoids; Tubulin; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles; Verapamil | 2001 |
The farnesyl protein transferase inhibitor SCH66336 is a potent inhibitor of MDR1 product P-glycoprotein.
Topics: 3T3 Cells; Adenosine Triphosphate; Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Cell Line; CHO Cells; Cricetinae; Daunorubicin; Drug Synergism; Enzyme Inhibitors; Farnesyltranstransferase; Genes, MDR; Humans; Hydrolysis; Mice; Paclitaxel; Piperidines; Pyridines; Rhodamine 123; Tamoxifen; Vinblastine | 2001 |
Effects of Taxotere on invasive potential and multidrug resistance phenotype in pancreatic carcinoma cell line SUIT-2.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biocompatible Materials; Carcinoma; Collagen; Docetaxel; Drug Combinations; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorescent Dyes; Humans; In Vitro Techniques; Laminin; Neoplasm Invasiveness; Paclitaxel; Pancreatic Neoplasms; Phenotype; Proteoglycans; Rhodamine 123; RNA, Neoplasm; Taxoids; Tumor Cells, Cultured | 2001 |
Digoxin up-regulates MDR1 in human colon carcinoma Caco-2 cells.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cell Division; Digoxin; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Kinetics; Paclitaxel; Rhodamine 123; RNA, Messenger; Up-Regulation | 2002 |
Overcoming the blood-brain barrier to taxane delivery for neurodegenerative diseases and brain tumors.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Blood-Brain Barrier; Brain Neoplasms; Cells, Cultured; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Design; Endothelial Cells; Male; Microtubules; Molecular Conformation; Neurodegenerative Diseases; Neurofibrillary Tangles; Paclitaxel; Rats; Rats, Sprague-Dawley; Rhodamine 123; Succinic Acid; Taxoids | 2003 |
The expression of P-glycoprotein does influence the distribution of novel fluorescent compounds in solid tumour models.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Multiple; Fluoresceins; Fluorescent Dyes; Humans; Microscopy, Confocal; Paclitaxel; Rhodamine 123; Spheroids, Cellular | 2003 |
Avermectins inhibit multidrug resistance of tumor cells.
Topics: Animals; Cell Division; Cell Line, Tumor; Cell Survival; Cyclosporine; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Synergism; Fluoresceins; Fluorescence; Humans; Ivermectin; Leukemia P388; Male; Mice; Paclitaxel; Rhodamine 123; Russia; Vincristine | 2004 |
Chemical modification of paclitaxel (Taxol) reduces P-glycoprotein interactions and increases permeation across the blood-brain barrier in vitro and in situ.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Endothelial Cells; Endothelium, Vascular; In Vitro Techniques; Male; Microcirculation; Paclitaxel; Permeability; Rats; Rats, Sprague-Dawley; Rhodamine 123; Structure-Activity Relationship | 2005 |
Adaptive response to increased bile acids: induction of MDR1 gene expression and P-glycoprotein activity in renal epithelial cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile Acids and Salts; Cell Line; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholic Acid; Cyclosporine; Deoxycholic Acid; Dogs; Enzyme Inhibitors; Epithelial Cells; Gastrointestinal Agents; Gene Expression Regulation; Kidney; Paclitaxel; Rhodamine 123; Taurocholic Acid | 2007 |
Modification of multidrug resistance of tumor cells by ionizing radiation.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Cell Count; Cell Line, Tumor; Combined Modality Therapy; Cyclosporine; Daunorubicin; Dose-Response Relationship, Radiation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Laryngeal Neoplasms; Paclitaxel; Radiation, Ionizing; Reactive Oxygen Species; Rhodamine 123; Time Factors; Vincristine | 2008 |
Stereoselective regulation of MDR1 expression in Caco-2 cells by cetirizine enantiomers.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cetirizine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Neoplasm; Flow Cytometry; Gene Expression Regulation, Neoplastic; Histamine H1 Antagonists, Non-Sedating; Humans; Paclitaxel; Rhodamine 123; Stereoisomerism | 2007 |
Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoprotein.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Butadienes; Cell Line, Tumor; Down-Regulation; Epidermal Growth Factor; Fibroblast Growth Factor 2; Humans; Mitogen-Activated Protein Kinases; Nitriles; Paclitaxel; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Rhodamine 123; RNA Interference; Time Factors; Transcription, Genetic; Up-Regulation | 2007 |
The characteristics of Hep-2 cell with multiple drug resistance induced by Taxol.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma; Cell Cycle; Cell Line, Tumor; Cisplatin; Deoxycytidine; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Dyes; Fluorouracil; Gemcitabine; Humans; Laryngeal Neoplasms; Multidrug Resistance-Associated Proteins; Paclitaxel; Rhodamine 123 | 2007 |
Histone deacetylase inhibitor apicidin-mediated drug resistance: involvement of P-glycoprotein.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Drug Resistance, Multiple; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Paclitaxel; Peptides, Cyclic; Rhodamine 123 | 2008 |
Enhanced oral bioavailability of paclitaxel by D-alpha-tocopheryl polyethylene glycol 400 succinate in mice.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Caco-2 Cells; Ethanol; Glycerol; Humans; Injections, Intravenous; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Paclitaxel; Permeability; Polyethylene Glycols; Rhodamine 123; Solvents; Steroid Hydroxylases; Vitamin E | 2008 |
Quinoline derivative KB3-1 potentiates paclitaxel induced cytotoxicity and cycle arrest via multidrug resistance reversal in MES-SA/DX5 cancer cells.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-2-Associated X Protein; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Survival; Cytochromes c; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; In Situ Nick-End Labeling; Indicators and Reagents; Microscopy, Confocal; Microscopy, Fluorescence; Paclitaxel; Quinolines; Rhodamine 123 | 2008 |
Inhibition of P-glycoprotein-mediated paclitaxel resistance by reversibly linked quinine homodimers.
Topics: Adenocarcinoma; Adenosine Triphosphatases; Affinity Labels; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dimerization; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Molecular Structure; Paclitaxel; Prazosin; Quinine; Rhodamine 123; Verapamil | 2009 |
Paclitaxel-resistance conferred by altered expression of efflux and influx transporters for paclitaxel in the human hepatoma cell line, HepG2.
Topics: Doxorubicin; Drug Resistance, Neoplasm; Hep G2 Cells; Humans; Liver; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters, Sodium-Independent; Paclitaxel; Probenecid; Rhodamine 123; RNA, Messenger; Sodium Azide; Solute Carrier Organic Anion Transporter Family Member 1B3; Sulfobromophthalein; Verapamil | 2009 |
Syl611, a novel semisynthetic taxane derivative, reverses multidrug resistance by p-glycoprotein inhibition and facilitating inward transmembrane action.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; KB Cells; Paclitaxel; Permeability; Rhodamine 123; Taxoids; Verapamil | 2010 |
Effect of Thai plant extracts on P-glycoprotein function and viability in paclitaxel-resistant HepG2 cells.
Topics: Annonaceae; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Hep G2 Cells; Herbal Medicine; Humans; Multidrug Resistance-Associated Proteins; Paclitaxel; Phytotherapy; Plant Extracts; Rhodamine 123; Rutaceae; Thailand; Tumor Cells, Cultured; Verapamil | 2010 |
Pgp inhibition by UIC2 antibody can be followed in vitro by using tumor-diagnostic radiotracers, 99mTc-MIBI and 18FDG.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Female; Fluorodeoxyglucose F18; Glucose; Humans; Ovarian Neoplasms; Paclitaxel; Protein Binding; Rhodamine 123; Technetium Tc 99m Sestamibi; Tumor Cells, Cultured | 2010 |
Kuguacin J isolated from Momordica charantia leaves inhibits P-glycoprotein (ABCB1)-mediated multidrug resistance.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Fluoresceins; Humans; Molecular Structure; Momordica charantia; Paclitaxel; Plant Leaves; Prazosin; Rhodamine 123; Triterpenes; Uterine Cervical Neoplasms; Vinblastine | 2012 |
Reversal of multidrug resistance by co-delivery of tariquidar (XR9576) and paclitaxel using long-circulating liposomes.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Liposomes; Molecular Targeted Therapy; Paclitaxel; Particle Size; Quinolines; Rhodamine 123; Surface Properties | 2011 |
The role of paclitaxel in the development and treatment of multidrug resistant cancer cell lines.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Death; Cell Line, Tumor; Colonic Neoplasms; Disease Progression; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glioblastoma; Glutathione; Humans; Inactivation, Metabolic; Paclitaxel; Rhodamine 123; RNA, Messenger; Vascular Endothelial Growth Factor A | 2011 |
Nanohybrid systems of non-ionic surfactant inserting liposomes loading paclitaxel for reversal of multidrug resistance.
Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Line, Tumor; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Compounding; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glycerol; Humans; Lipids; Liposomes; Lung Neoplasms; Nanotechnology; Paclitaxel; Particle Size; Poloxamer; Polyethylene Glycols; Rhodamine 123; Solubility; Stearic Acids; Surface-Active Agents; Technology, Pharmaceutical; Time Factors | 2012 |
Crizotinib (PF-02341066) reverses multidrug resistance in cancer cells by inhibiting the function of P-glycoprotein.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Crizotinib; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Mice; Mice, Nude; Neoplasms; Paclitaxel; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Rhodamine 123; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
Effects of gelucire content on stability, macrophage interaction and blood circulation of nanoparticles engineered from nanoemulsions.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calorimetry, Differential Scanning; Drug Carriers; Drug Stability; Emulsions; Fatty Alcohols; Humans; Macrophages; Mice; Mice, Inbred BALB C; Nanoparticles; Oils; Paclitaxel; Particle Size; Polyethylene Glycols; Reactive Oxygen Species; Rhodamine 123; Spectroscopy, Fourier Transform Infrared; Water | 2012 |
Cellular interactions of a water-soluble supramolecular polymer complex of carbon nanotubes with human epithelial colorectal adenocarcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Buffers; Caco-2 Cells; Cell Survival; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Electric Impedance; Humans; Methacrylates; Microscopy, Electron, Scanning; Nanotubes, Carbon; Paclitaxel; Polymerization; Rhodamine 123; Solubility; Water | 2012 |
Mechanism of inhibition of P-glycoprotein mediated efflux by Pluronic P123/F127 block copolymers: relationship between copolymer concentration and inhibitory activity.
Topics: Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Line, Tumor; Chemistry, Pharmaceutical; Doxorubicin; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Membrane Potential, Mitochondrial; Micelles; Paclitaxel; Poloxalene; Polyethylenes; Polymers; Polypropylenes; Rhodamine 123; Rhodamines | 2013 |
Bipiperidinyl derivatives of 23-hydroxybetulinic acid reverse resistance of HepG2/ADM and MCF-7/ADR cells.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; MCF-7 Cells; Molecular Docking Simulation; Paclitaxel; Piperidines; Rhodamine 123; Triterpenes; Verapamil; Vincristine | 2013 |
Multifunctional nanoparticles based on a single-molecule modification for the treatment of drug-resistant cancer.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorouracil; Humans; Hydrolysis; Models, Chemical; Nanoparticles; Neoplasms; Paclitaxel; Polyethylene Glycols; Rhodamine 123; Vitamin E | 2013 |
Grape seed procyanidin reversal of p-glycoprotein associated multi-drug resistance via down-regulation of NF-κB and MAPK/ERK mediated YB-1 activity in A2780/T cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biflavonoids; Catechin; Cell Line; Cell Nucleus; Doxorubicin; Drug Resistance, Multiple; Gene Expression Regulation; Humans; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Paclitaxel; Proanthocyanidins; Protein Transport; Rhodamine 123; RNA, Messenger; Seeds; T-Lymphocytes; Vitis; Y-Box-Binding Protein 1 | 2013 |
Trantinterol, a novel β2-adrenoceptor agonist, noncompetitively inhibits P-glycoprotein function in vitro and in vivo.
Topics: Adenosine Triphosphatases; Adrenergic beta-Agonists; Animals; Antibodies, Monoclonal; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport; Caco-2 Cells; Clenbuterol; Cyclosporine; Digoxin; Dogs; Drug Evaluation, Preclinical; Humans; Madin Darby Canine Kidney Cells; Male; Paclitaxel; Rats; Rats, Wistar; Rhodamine 123 | 2015 |
6,7-Dimethoxy-2-{2-[4-(1H-1,2,3-triazol-1-yl)phenyl]ethyl}-1,2,3,4-tetrahydroisoquinolines as superior reversal agents for P-glycoprotein-mediated multidrug resistance.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Benzamides; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Daunorubicin; Drug Resistance, Neoplasm; Humans; K562 Cells; Paclitaxel; Protein Binding; Rhodamine 123; Structure-Activity Relationship; Tetrahydroisoquinolines; Triazoles; Vincristine | 2015 |
Reversion of multidrug resistance by a pH-responsive cyclodextrin-derived nanomedicine in drug resistant cancer cells.
Topics: Acetylation; Adenosine Triphosphatases; alpha-Cyclodextrins; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cytoskeleton; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Endocytosis; Energy Metabolism; Humans; Hydrogen-Ion Concentration; Membrane Potential, Mitochondrial; Nanomedicine; Nanoparticles; Neoplasms; Paclitaxel; Rhodamine 123 | 2015 |
Nobiletin enhances the efficacy of chemotherapeutic agents in ABCB1 overexpression cancer cells.
Topics: Adsorption; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Cell Cycle; Cell Line, Tumor; Docetaxel; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Flavones; Fluorouracil; Humans; Intracellular Space; Models, Biological; Molecular Docking Simulation; Paclitaxel; Rhodamine 123; Signal Transduction; Taxoids; Treatment Outcome | 2015 |
Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Culture Media; Electrophoresis, Polyacrylamide Gel; Humans; Moths; Mutagenesis, Site-Directed; Nicardipine; Paclitaxel; Protein Isoforms; Rhodamine 123; Vinblastine | 2017 |
Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzylisoquinolines; Caspases; Cell Cycle; Cell Line, Tumor; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lactic Acid; Lipids; Nanoparticles; Oligopeptides; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Reactive Oxygen Species; Rhodamine 123; Tubulin | 2017 |
N-Deoxycholic acid-N,O-hydroxyethyl Chitosan with a Sulfhydryl Modification To Enhance the Oral Absorptive Efficiency of Paclitaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Chitosan; Deoxycholic Acid; Drug Carriers; Fluorescent Dyes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Micelles; Models, Animal; Paclitaxel; Permeability; Rats; Rhodamine 123; Sulfhydryl Compounds; Tight Junctions | 2017 |
Drug resistance via radixin-mediated increase of P-glycoprotein membrane expression during SNAI1-induced epithelial-mesenchymal transition in HepG2 cells.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane; Cytoskeletal Proteins; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Genetic Vectors; Hep G2 Cells; Humans; Membrane Glycoproteins; Membrane Proteins; Microfilament Proteins; Neoplasms; Paclitaxel; Rhodamine 123; RNA, Messenger; RNA, Small Interfering; Snail Family Transcription Factors; Transfection | 2021 |
Reversal of cisplatin resistance in non-small cell lung cancer stem cells by Taxus chinensis var.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cisplatin; Drug Combinations; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Neoplastic Stem Cells; Plant Extracts; Rhodamine 123; Signal Transduction; Taxus; Vault Ribonucleoprotein Particles | 2016 |
Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein.
Topics: Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Humans; Karyotyping; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Sequence Homology, Amino Acid | 2000 |
Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport, Active; Biomarkers; Cells, Cultured; Drug Interactions; Fluorescent Dyes; Humans | 2003 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |