Page last updated: 2024-08-24

rhodamine 123 and mitoxantrone

rhodamine 123 has been researched along with mitoxantrone in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.88)18.2507
2000's10 (58.82)29.6817
2010's6 (35.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cianfriglia, M; Eisterer, W; Gotwald, M; Hilbe, W; Hofmann, J; Ludescher, C; Thaler, J; Zabernigg, A1
Bates, SE; Dean, M; Honjo, Y; Hrycyna, CA; Litman, T; Medina-Pérez, WY; Robey, RW; van de Laar, A; Yan, QW1
Bates, SE; Dietel, M; Hohenberger, P; Jordan, A; Lage, H; Litman, T; Stein, U; Walther, W1
Ozvegy, C; Sarkadi, B; Váradi, A1
Bernard, M; Berthou, C; Campos, L; de Crémoux, P; Delain, M; Drenou, B; Falkenrodt, A; Fernandes, J; Garnache, F; Guilhot, F; Harousseau, JL; Hunault-Berger, M; Kara-Slimane, F; Lioure, B; Moreau, P; Mounier, C; Mugneret, F; Solary, E; Witz, B1
Ambudkar, SV; Chearwae, W; Limtrakul, P; Phisalphong, C; Shukla, S1
Bougnoux, P; Chourpa, I; Dubois, P; Goré, J; Mahéo, K; Vibet, S1
Ma, Y; Wink, M1
Drewe, J; Gutmann, H; Huwyler, J; Krähenbühl, S; Poller, B1
Bogani, C; Cipriani, G; D'Amico, M; Fantappiè, O; Formigli, L; Mazzanti, R; Sassoli, C; Solazzo, M; Tani, A1
Fu, LW; Liang, YJ; Su, XD; Wang, F; Wu, XP1
Ambudkar, SV; Baer, MR; Bhullar, J; Cai, L; Chen, ZS; Fang, HB; Natarajan, K; Sen, R; Shukla, S1
Ambudkar, SV; Chen, JJ; Chen, ZS; Dai, CL; Deng, W; Fu, LW; Liang, YJ; Ohnuma, S; Zeng, MS; Zhao, XQ1
Ambudkar, SV; Fung, KL; Gottesman, MM; Kimchi-Sarfaty, C; Lund, PE; Ohnuma, S; Pan, J; Pixley, JN1
Bates, S; Litman, T; Nagy, Z; Ozvegy, C; Sarkadi, B; Szakács, G; Váradi, A1
Bauer, KS; Doyle, LA; Fang, HB; Hassel, B; Nakanishi, T; Pumplin, DW; Ross, DD; Wei, Y; Wu, S1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M1

Trials

1 trial(s) available for rhodamine 123 and mitoxantrone

ArticleYear
Quinine as a multidrug resistance inhibitor: a phase 3 multicentric randomized study in adult de novo acute myelogenous leukemia.
    Blood, 2003, Aug-15, Volume: 102, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Prospective Studies; Quinine; Rhodamine 123

2003

Other Studies

16 other study(ies) available for rhodamine 123 and mitoxantrone

ArticleYear
Low frequency of activity of P-glycoprotein (P-170) in acute lymphoblastic leukemia compared to acute myeloid leukemia.
    Leukemia, 1995, Volume: 9, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Rhodamine 123; Rhodamines; Survival Analysis

1995
Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells.
    Cancer research, 2001, Sep-15, Volume: 61, Issue:18

    Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Camptothecin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Genes, MDR; Genetic Vectors; HeLa Cells; Humans; Irinotecan; Mitoxantrone; Mutation; Neoplasm Proteins; Rhodamine 123; RNA, Messenger; Substrate Specificity; Topotecan; Transfection; Tumor Cells, Cultured; Vaccinia virus

2001
Impact of BCRP/MXR, MRP1 and MDR1/P-Glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer cells.
    International journal of cancer, 2002, Feb-20, Volume: 97, Issue:6

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Calcium Channel Blockers; DNA Primers; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Multiple; Fluorescent Dyes; Gastrointestinal Neoplasms; Gene Expression Regulation; Genes, MDR; Hot Temperature; Humans; Indenes; Mitoxantrone; Multidrug Resistance-Associated Proteins; MutS Homolog 3 Protein; Mycotoxins; Neoplasm Proteins; Propionates; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; RNA, Messenger; RNA, Neoplasm; Stomach Neoplasms; Verapamil

2002
Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation.
    The Journal of biological chemistry, 2002, Dec-13, Volume: 277, Issue:50

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Base Sequence; Benzimidazoles; Biological Transport; Cell Membrane; DNA Primers; Flow Cytometry; HL-60 Cells; Humans; Hydrolysis; Kinetics; Mitoxantrone; Neoplasm Proteins; Point Mutation; Recombinant Proteins; Rhodamine 123; Spodoptera; Substrate Specificity

2002
Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.
    Molecular and cellular biochemistry, 2007, Volume: 296, Issue:1-2

    Topics: Adenosine Triphosphate; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Beryllium; Cell Line, Tumor; Chlorophyll; Curcumin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Fluoresceins; Fluorescent Dyes; Fluorides; Humans; Mitoxantrone; Molecular Structure; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Organic Anion Transporters; Rhodamine 123; Vinblastine

2007
Differential subcellular distribution of mitoxantrone in relation to chemosensitization in two human breast cancer cell lines.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:5

    Topics: Acetylcysteine; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Membrane; Cell Nucleus; Cell Survival; Cytosol; Docosahexaenoic Acids; Female; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Microscopy, Confocal; Mitoxantrone; Molecular Structure; Reactive Oxygen Species; Rhodamine 123; Time Factors

2007
Lobeline, a piperidine alkaloid from Lobelia can reverse P-gp dependent multidrug resistance in tumor cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2008, Volume: 15, Issue:9

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Lobelia; Lobeline; Mitoxantrone; Rhodamine 123

2008
Regulation of BCRP (ABCG2) and P-glycoprotein (ABCB1) by cytokines in a model of the human blood-brain barrier.
    Cellular and molecular neurobiology, 2010, Volume: 30, Issue:1

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Cell Line; Cytokines; Gene Expression Regulation; Humans; Interleukin-1beta; Interleukin-6; Mitoxantrone; Models, Biological; Neoplasm Proteins; Rhodamine 123; RNA, Messenger; Tumor Necrosis Factor-alpha

2010
Mitochondrial expression and functional activity of breast cancer resistance protein in different multiple drug-resistant cell lines.
    Cancer research, 2009, Sep-15, Volume: 69, Issue:18

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blotting, Western; Cell Line; Cell Line, Tumor; Cytosol; Dogs; Drug Resistance, Multiple; Humans; Microscopy, Confocal; Mitochondria; Mitoxantrone; Neoplasm Proteins; Rhodamine 123; RNA, Small Interfering; Transfection

2009
ABCG2-overexpressing S1-M1-80 cell xenografts in nude mice keep original biochemistry and cell biological properties.
    Chinese journal of cancer, 2012, Volume: 31, Issue:3

    Topics: Adenosine; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Colonic Neoplasms; Diketopiperazines; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Heterocyclic Compounds, 4 or More Rings; Humans; Inhibitory Concentration 50; KB Cells; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitoxantrone; Neoplasm Proteins; Neoplasm Transplantation; Rhodamine 123; Topotecan

2012
The novel BCR-ABL and FLT3 inhibitor ponatinib is a potent inhibitor of the MDR-associated ATP-binding cassette transporter ABCG2.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Carbocyanines; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Chlorophyll; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; fms-Like Tyrosine Kinase 3; Fusion Proteins, bcr-abl; Humans; Imidazoles; Inhibitory Concentration 50; Mitoxantrone; Neoplasm Proteins; Protein Binding; Pyridazines; Rhodamine 123; Topotecan

2012
Tandutinib (MLN518/CT53518) targeted to stem-like cells by inhibiting the function of ATP-binding cassette subfamily G member 2.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Jun-14, Volume: 49, Issue:3

    Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Resistance, Neoplasm; Humans; Mice; Mitoxantrone; Neoplasm Proteins; Neoplastic Stem Cells; NIH 3T3 Cells; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Rhodamine 123

2013
MDR1 synonymous polymorphisms alter transporter specificity and protein stability in a stable epithelial monolayer.
    Cancer research, 2014, Jan-15, Volume: 74, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Biotinylation; Cell Line; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Haplotypes; Humans; Mitoxantrone; Mutation; Polymorphism, Genetic; Protein Stability; Recombinant Proteins; Rhodamine 123; Swine

2014
Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells.
    Biochemical and biophysical research communications, 2001, Jul-06, Volume: 285, Issue:1

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Membrane; Cloning, Molecular; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasm Proteins; Recombinant Proteins; Spodoptera; Tumor Cells, Cultured

2001
Functional characterization of human breast cancer resistance protein (BCRP, ABCG2) expressed in the oocytes of Xenopus laevis.
    Molecular pharmacology, 2003, Volume: 64, Issue:6

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Oocytes; Xenopus laevis

2003
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2010