Compounds > rhodamine 123
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rhodamine 123 and cyclosporine

rhodamine 123 has been researched along with cyclosporine in 101 studies

Research

Studies (101)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's31 (30.69)18.2507
2000's48 (47.52)29.6817
2010's21 (20.79)24.3611
2020's1 (0.99)2.80

Authors

AuthorsStudies
Bauer, HC; Hegmann, EJ; Kerbel, RS1
Elmquist, WF; Miller, DW; Wang, Q; Yang, H1
Bello-Reuss, E; Ernest, S3
Bates, SE; Dickstein, B; Fojo, AT; Lee, JS; Spolyar, M1
Brezden, CB; Hedley, DW; Rauth, AM1
Patterson, FK; Wigler, PW1
Rayner, S; Rhodes, T; Twentyman, PR1
Baumgartner, G; Hamilton, G; Schirmböck, M; Sherwood, ER; Thalhammer, T; Theyer, G1
Eisterer, W; Hilbe, W; Hofmann, J; Ludescher, C; Thaler, J1
Miotto, G; Pizzo, P; Rizzuto, R; Siliprandi, N; Venerando, R1
Gupta, S; Wein, D1
Bowen-Yacyshyn, MB; Pilarski, LM; Yacyshyn, BR1
Aggarwal, S; Andreana, A; Gollapudi, S; Gupta, S; Tsuruo, T; Wien, D1
Aszalos, A; Goldenberg, S; Gottesman, MM; McKinney, L; Schoenlein, PV; Weaver, JL1
Hayes, ML; Joiner, KA; Luft, BJ; Silverman, JA1
Ashman, LK; Sincock, PM1
Bertrán, J; García-López, J; Pétriz, J; Sánchez, J1
Coelho, AM; Dobbin, JA; Harab, RC; Maia, RC; Rumjanek, VM; Vasconcelos, FC1
Haberl, I; Hamilton, G; Schaufler, K; Swatonek, H; Thalhammer, T; Theyer, G; Ulsperger, E; Wenzl, E1
Belch, AR; Murphy, GF; Pilarski, LM; Yatscoff, RW1
Béliveau, R; Jetté, L; Murphy, GF1
Aszalos, A; Weaver, JL1
Dintaman, JM; Kim, AE; Silverman, JA; Waddell, DS1
de Giuli, R; Lehnert, M; Twentyman, PR1
Matha, V; Podsiadlowski, L; Vilcinskas, A1
de Paula, EF; Harab, RC; Marques-Santos, LF; Rumjanek, VM1
Aszalos, A; Molnár, J; Ocsovszki, I; Szabó, D; Szabó, G1
Bamdad, M; Brousseau, P; Denizeau, F1
Dintaman, JM; Silverman, JA1
Kajikawa, T; Mishima, HK; Murakami, T; Takano, M1
Huang, ZH; Murakami, T; Nagai, J; Okochi, A; Takano, M; Yumoto, R1
Blom-Roosemalen, MC; Breimer, DD; de Boer, AG; van der Sandt, IC1
Hail, N; Lotan, R1
Murakami, T; Nagai, J; Nasu, R; Sanemasa, M; Takano, M; Yumoto, R1
Brunner, M; Moeslinger, T; Spieckermann, PG1
Boschi, E; Demontis, GC; Longoni, B; Mosca, F; Ratto, GM1
Audus, KL; Backstrom, G; Hamilton, KO; Yazdanian, MA1
Benet, LZ; Lantz, MV; Parasrampuria, DA1
Azevedo, I; Keating, E; Martel, F1
Auchère, D; Banide, H; Farinotti, R; Lacour, B; Leroy, C; Tardivel, S; Veau, C1
Hirsch-Ernst, KI; Kahl, GF; Rustenbeck, I; Ziemann, C1
Cohen, D; Uchiyama-Kokubu, N; Watanabe, T1
Ambudkar, SV; Kasir, J; Kimchi-Sarfaty, C; Rahamimoff, H1
Cen, J; Chen, Z; Fu, J; Ruan, C1
Mather, MW; Rottenberg, H1
Endo, T; Kimura, O; Sakata, M1
Anand, BS; Dey, S; Ganapathy, V; Jain-Vakkalagadda, B; Kaliki, P; Mitra, AK; Pal, D; Patel, J1
Burckart, GJ; Donnenberg, AD; Donnenberg, VS; Iacono, A; Wilson, JW; Zeevi, A1
Maia, RC; Marques-Santos, LF; Oliveira, JG; Rumjanek, VM1
Askari, MD; Vo-Dinh, T1
Dogan, AL; Faussat, AM; Legrand, O; Marie, JP; Perrot, JY1
Drinyaev, VA; Ermakova, NV; Korystov, YN; Kruglyak, EB; Kublik, LN; Levitman, MKh; Mosin, VA; Novik, TS; Shaposhnikova, VV; Sterlina, TS1
Dohgu, S; Egawa, T; Kai, M; Kataoka, Y; Naito, M; Nakagawa, S; Niwa, M; Sawada, Y; Takata, F; Tsuruo, T; Yamauchi, A1
Liu, GQ; Yang, ZY1
Braga, F; Capella, LS; Capella, MA; Lopes, AG; Nascimento, CR; Santos, OR1
Balkay, L; Esik, O; Galuska, L; Hernádi, Z; Krasznai, Z; Krasznai, ZT; Márián, T; Szabó, G; Szabó-Péli, J; Trón, L1
He, Y; Zeng, S1
Chaoui, D; Faussat, AM; Klein, C; Legrand, O; Majdak, P; Marie, JP; Pasco, S; Perrot, JY; Tang, R1
Chao, PD; Chiang, HM; Hou, YC; Hsiu, SL; Tsai, SY; Wen, KC1
Ambudkar, SV; Calcagno, AM; Gottesman, MM; Kim, IW; Kimchi-Sarfaty, C; Oh, JM; Sauna, ZE1
Gäbel, G; Honscha, KU; Honscha, W; Kneuer, C1
Emel'yanov, MO; Korystov, YN; Korystova, AF; Kublik, LN; Shaposhnikova, VV1
Baldes, C; Becker, U; Daum, N; Ehrhardt, C; Kim, KJ; Lehr, CM; Ruprecht, KW; Schaefer, UF1
Mealey, KL; West, CL1
Ackerley, C; Clarke, DM; De Rosa, MF; Ito, S; Lingwood, C; Wang, B1
Hui-Wen, Y; Xiao-Dong, L; Zhi-Hong, Y1
Liu, HY; Liu, X; Liu, XD; Liu, YC; Wang, GJ; Xie, L; Yang, HW; Zhang, DM1
Berardi, F; Colabufo, NA; Contino, M; Inglese, C; Niso, M; Perrone, R1
Beghin, D; Claude, N; Delongeas, JL; Farinotti, R; Forestier, F; Gil, S1
Chen, SG; Li, GY; Liu, JZ; Wang, CB; Wang, LX; Zhang, B1
DeFranco, DB; Devinney, MJ; Dineley, KE; Hastings, TG; Malaiyandi, LM; Vergun, O1
Mehvar, R; Parasrampuria, R1
Dorababu, M; Naruhashi, K; Nishimura, A; Prabha, T; Shibata, N; Sugioka, N; Takada, K1
Hayashi, M; Kishimoto, H; Takizawa, Y; Tomita, M1
Akashi, H; Kida, M; Mori, M; Mori, N; Murakami, T; Yokooji, T; Yoshihara, S1
Arnoult, C; Barattin, R; Bourges, K; Boutonnat, J; D'Hardemare, AD; Gerby, B; Hardy, G; Olivares, J; Ronot, X1
Fodor, Z; Galuska, L; Goda, K; Hernádi, Z; Krasznai, ZT; Mikecz, P; Szabó, G; Tóth, A1
Carsetti, R; D'Amelio, R; Diamanti, AP; Germano, V; Giorda, E; Laganà, B; Podestà, E; Rosado, M; Scarsella, M1
Cai-Hong, Z; Fang, M; Jin-Hua, J; Li, H; Ning, W; Qing-Duan, W; Xiao-Juan, G; Yan, Z1
Du, GH; Mei, C; Qi, Y; Sun, X; Sun, XB; Yang, ZH1
Fujita-Hamabe, W; Kishioka, S; Kobori, T; Nakamoto, K; Nawa, A; Nishida, M; Tokuyama, S1
Li, H; Shen, GL; Sun, HX; Yuan, M; Zhuang, XM1
Bestard, O; Cassis, L; Castaño, E; Cerezo, G; Cruzado, JM; Franquesa, Ml; Grinyó, JM; Herrero-Fresneda, I; Llaudó, I; Lloberas, N; Pétriz, J; Torras, J1
Barot, M; Gokulgandhi, MR; Mitra, AK; Pal, D1
Liu, X; Roberts, MS; Thorling, CA; Weiss, M1
Junco, JJ; Kim, DJ; Liang, H; Malik, G; Mancha, A; Slaga, TJ; Wei, SJ1
Ballandonne, C; Bouet, V; Boulouard, M; Claeysen, S; Corvaisier, S; Cresteil, T; Dallemagne, P; Freret, T; Gaven, F; Giannoni, P; Hedou, D; Lecoutey, C; Malzert Fréon, A; Mignani, S; Rochais, C; Since, M1
Fan, H; Fawcett, JP; Gu, J; Guo, Y; Liu, J; Ma, W; Sun, Y; Wang, T; Yang, J; Yang, Y; Yang, Z1
Fukami, T; Suzuki, T; Tomono, K1
Goda, K; Kárpáti, L; Kertész, I; Krasznai, Z; Krasznai, ZT; Márián, T; Máté, G; Szabó Judit, P; Szalóki, G; Trencsényi, G1
de Graaf, IA; de Jager, MH; Groothuis, GM; Li, M1
Almeida, IC; Bechara, GH; Ferreira, Jda S; Gandara, AC; Lara, FA; Nascimento-Silva, MC; Oliveira, PL; Pohl, PC; Sorgine, MH; Vaz, Ida S1
Deng, YS; Qiu, XW; Sun, X; Wang, R1
Khamenehfar, A; Li, PCH; Sharifi Noghabi, H; Soo, M1
Kim, HS; Lee, JS; Park, JH; Sharma, S; Shin, JK; Yoon, S1
Hargrove, P; Kim, RB; Lan, LB; Lecureur, V; Schuetz, EG; Schuetz, JD; Sun, D1
Bates, S; Litman, T; Nagy, Z; Ozvegy, C; Sarkadi, B; Szakács, G; Váradi, A1
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ1
Globisch, C; Kassack, MU; Klinkhammer, W; Müller, H; Pajeva, IK; Wiese, M1

Trials

1 trial(s) available for rhodamine 123 and cyclosporine

ArticleYear
Cyclosporine diminishes multidrug resistance in K562/ADM cells and improves complete remission in patients with acute myeloid leukemia.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2009, Volume: 63, Issue:8

    Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Survival; Cyclosporine; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Fluorescent Dyes; Humans; Idarubicin; Inhibitory Concentration 50; K562 Cells; Leukemia, Myeloid, Acute; Male; Rhodamine 123; Time Factors; Treatment Outcome; Verapamil

2009

Other Studies

100 other study(ies) available for rhodamine 123 and cyclosporine

ArticleYear
Expression and functional activity of P-glycoprotein in cultured cerebral capillary endothelial cells.
    Cancer research, 1992, Dec-15, Volume: 52, Issue:24

    Topics: Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Capillaries; Cells, Cultured; Cyclosporine; Drug Resistance; Endothelium, Vascular; Humans; Membrane Glycoproteins; Mice; Rhodamine 123; Rhodamines; Swine; Verapamil

1992
Effect of the p-glycoprotein inhibitor, cyclosporin A, on the distribution of rhodamine-123 to the brain: an in vivo microdialysis study in freely moving rats.
    Biochemical and biophysical research communications, 1995, Jun-26, Volume: 211, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Cerebral Cortex; Cyclosporine; Locomotion; Male; Microdialysis; Rats; Rats, Wistar; Rhodamine 123; Rhodamines; Tissue Distribution

1995
Expression and function of P-glycoprotein in a mouse kidney cell line.
    The American journal of physiology, 1995, Volume: 269, Issue:2 Pt 1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cell Polarity; Cricetinae; Cyclosporine; Epithelium; Homeostasis; Immunologic Techniques; Kidney; Kidney Tubules, Proximal; Mice; Mice, Transgenic; Rhodamine 123; Rhodamines; RNA, Messenger; Verapamil

1995
Differential modulation of P-glycoprotein transport by protein kinase inhibition.
    Biochemistry, 1993, Sep-07, Volume: 32, Issue:35

    Topics: Affinity Labels; Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Carrier Proteins; Cyclosporine; Dactinomycin; Dihydropyridines; Drug Resistance; Humans; Isoenzymes; Membrane Glycoproteins; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rhodamine 123; Rhodamines; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine

1993
Constitutive expression of P-glycoprotein as a determinant of loading with fluorescent calcium probes.
    Cytometry, 1994, Dec-01, Volume: 17, Issue:4

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium; CHO Cells; Cricetinae; Cricetulus; Cyclosporine; Cytosol; Female; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Humans; Indoles; Rhodamine 123; Rhodamines; Verapamil

1994
Reversal agent inhibition of the multidrug resistance pump in human leukemic lymphoblasts.
    Biochimica et biophysica acta, 1994, Jan-03, Volume: 1189, Issue:1

    Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cyclosporine; Drug Resistance; Humans; Leukemia; Membrane Glycoproteins; Propranolol; Propylamines; Quinidine; Quinine; Rhodamine 123; Rhodamines; Stereoisomerism; Tumor Cells, Cultured

1994
A comparison of rhodamine 123 accumulation and efflux in cells with P-glycoprotein-mediated and MRP-associated multidrug resistance phenotypes.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:9

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Drug Resistance, Multiple; Flow Cytometry; Hot Temperature; Humans; Lung Neoplasms; Mammary Neoplasms, Animal; Mice; Mitochondria; Phenotype; Rhodamine 123; Rhodamines; Time Factors; Tumor Cells, Cultured

1994
Role of the MDR-1-encoded multiple drug resistance phenotype in prostate cancer cell lines.
    The Journal of urology, 1993, Volume: 150, Issue:5 Pt 1

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cell Division; Cyclosporine; Doxorubicin; Drug Resistance; Humans; Male; Membrane Glycoproteins; Phenotype; Prostatic Neoplasms; Rhodamine 123; Rhodamines; Tamoxifen; Tumor Cells, Cultured; Verapamil

1993
Decreased potency of MDR-modulators under serum conditions determined by a functional assay.
    British journal of haematology, 1995, Volume: 91, Issue:3

    Topics: Acute Disease; Antimetabolites, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; CD8-Positive T-Lymphocytes; Cyclosporine; Dihydropyridines; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Flow Cytometry; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Rhodamine 123; Rhodamines; Verapamil

1995
Mitochondrial alterations induced by aspirin in rat hepatocytes expressing mitochondrially targeted green fluorescent protein (mtGFP).
    FEBS letters, 1996, Mar-18, Volume: 382, Issue:3

    Topics: Animals; Aspirin; Cell Survival; Cells, Cultured; Cyclosporine; Fluorescent Dyes; Green Fluorescent Proteins; Luminescent Proteins; Male; Mitochondria, Liver; Rats; Rats, Wistar; Rhodamine 123; Rhodamines; Transfection; Urea

1996
Expression of P-glycoprotein, encoded by MDR 1 gene, a metabolically active efflux pump in murine mast cells.
    Cancer letters, 1996, Mar-29, Volume: 101, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Western; Cyclosporine; Drug Resistance, Multiple; Mast Cells; Mice; Molecular Sequence Data; Polymerase Chain Reaction; Rhodamine 123; Rhodamines; RNA

1996
Xenobiotic transport differences in mouse mesangial cell clones expressing mdr1 and mdr3.
    The American journal of physiology, 1996, Volume: 270, Issue:3 Pt 1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Calcium; Cell Division; Cell Line; Cell Membrane; Clone Cells; Cyclosporine; Cyclosporins; Doxorubicin; Drug Resistance, Multiple; Gene Expression; Glomerular Mesangium; Kidney Tubules, Proximal; Kinetics; Mice; Mice, Transgenic; Rhodamine 123; Rhodamines; RNA, Messenger; Vinblastine; Xenobiotics

1996
Inhibition by rapamycin of P-glycoprotein 170-mediated export from normal lymphocytes.
    Scandinavian journal of immunology, 1996, Volume: 43, Issue:4

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; B-Lymphocytes; Biological Transport; Cell Line; Cyclosporine; Dose-Response Relationship, Immunologic; Fluorescent Dyes; Humans; Immunosuppressive Agents; Polyenes; Rhodamine 123; Rhodamines; Sirolimus; T-Lymphocytes

1996
Abnormal expression of a 170-kilodalton P-glycoprotein encoded by MDR1 gene, a metabolically active efflux pump, in CD4+ and CD8+ T cells from patients with human immunodeficiency virus type 1 infection.
    AIDS research and human retroviruses, 1996, Oct-10, Volume: 12, Issue:15

    Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclosporine; Female; Genes, MDR; HIV Seropositivity; Humans; Male; Rhodamine 123; Rhodamines; Zidovudine

1996
MDR1/P-glycoprotein function. I. Effect of hypotonicity and inhibitors on rhodamine 123 exclusion.
    The American journal of physiology, 1996, Volume: 270, Issue:5 Pt 1

    Topics: 3T3 Cells; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloride Channels; Cyclosporine; Flufenamic Acid; Humans; Hypotonic Solutions; Mice; Rhodamine 123; Rhodamines; Tumor Cells, Cultured

1996
Characterization of anti-Toxoplasma activity of SDZ 215-918, a cyclosporin derivative lacking immunosuppressive and peptidyl-prolyl-isomerase-inhibiting activity: possible role of a P glycoprotein in Toxoplasma physiology.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:9

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Chlorocebus aethiops; Coccidiostats; Cyclosporine; Cyclosporins; Enzyme Inhibitors; Female; Immunosuppressive Agents; Mice; Peptidylprolyl Isomerase; Rhodamine 123; Rhodamines; Sensitivity and Specificity; Toxoplasma; Verapamil; Vero Cells

1997
Expression of c-Kit and functional drug efflux are correlated in de novo acute myeloid leukaemia.
    Leukemia, 1997, Volume: 11, Issue:11

    Topics: Acute Disease; Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Fluorescent Antibody Technique, Indirect; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Phenotype; Proto-Oncogene Proteins c-kit; Rhodamine 123; Rhodamines; Tumor Cells, Cultured

1997
Comparative effect of verapamil, cyclosporin A and SDZ PSC 833 on rhodamine 123 transport and cell cycle in vinblastine-resistant Chinese hamster ovary cells overexpressing P-glycoprotein.
    Anti-cancer drugs, 1997, Volume: 8, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Cycle; Cell Line; CHO Cells; Cricetinae; Cyclosporine; Cyclosporins; DNA; Drug Resistance, Neoplasm; Flow Cytometry; Immunosuppressive Agents; Rhodamine 123; Rhodamines; Verapamil; Vinblastine

1997
Comparison between anthracyclines and rhodamine-123 accumulation in chronic lymphoid leukemia: effect of cyclosporin A and verapamil.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1998, Volume: 19, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Drug Resistance, Multiple; Female; Flow Cytometry; Fluorescent Dyes; Humans; Immunohistochemistry; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Rhodamine 123; Rhodamines; Tumor Cells, Cultured; Verapamil

1998
P-glycoprotein-mediated multidrug resistance is modulated by pretreatment with chemosensitizers in HCT-8 carcinoma cells in vitro.
    International journal of oncology, 1998, Volume: 12, Issue:5

    Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclosporine; Cyclosporins; Doxorubicin; Drug Resistance, Multiple; Epithelial Cells; Humans; Ileal Neoplasms; Ileocecal Valve; Kinetics; Phosphorylation; Rhodamine 123; Rhodamines; Tamoxifen; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Verapamil; Vinblastine

1998
Drug resistance in multiple myeloma: cyclosporin A analogues and their metabolites as potential chemosensitizers.
    Leukemia, 1998, Volume: 12, Issue:4

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; B-Lymphocytes; Biological Transport; Cyclosporine; Cyclosporins; Drug Resistance, Neoplasm; Humans; Immunosuppressive Agents; Multiple Myeloma; Rhodamine 123; Rhodamines; Tumor Cells, Cultured

1998
Drug binding to P-glycoprotein is inhibited in normal tissues following SDZ-PSC 833 treatment.
    International journal of cancer, 1998, May-29, Volume: 76, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Blotting, Western; Brain; Calcium Channel Blockers; Capillaries; Cyclosporine; Cyclosporins; Drug Interactions; Fluorescent Dyes; Injections, Subcutaneous; Iodine Radioisotopes; Kidney; Liver; Male; Microvilli; Photoaffinity Labels; Prazosin; Rats; Rats, Sprague-Dawley; Rhodamine 123; Rhodamines; Verapamil; Vinblastine

1998
Estimation of drug resistance by flow cytometry.
    Methods in molecular biology (Clifton, N.J.), 1998, Volume: 91

    Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Flow Cytometry; Genistein; Leukemia L5178; Mice; Probenecid; Recombinant Proteins; Rhodamine 123; Rhodamines; Transfection; Tumor Cells, Cultured; Verapamil

1998
Saquinavir, an HIV protease inhibitor, is transported by P-glycoprotein.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:3

    Topics: 3T3 Cells; Animals; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Cyclosporine; HIV Protease Inhibitors; Mice; Rhodamine 123; Rhodamines; Saquinavir

1998
Sensitive and rapid bioassay for analysis of P-glycoprotein-inhibiting activity of chemosensitizers in patient serum.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:2

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Assay; Breast Neoplasms; Cyclosporine; Female; Humans; Rhodamine 123; Sensitivity and Specificity; Verapamil

1996
Detection of a P-glycoprotein related pump in Chironomus larvae and its inhibition by verapamil and cyclosporin A.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 1998, Volume: 121, Issue:4

    Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Chironomidae; Cyclosporine; Immunohistochemistry; Insecticide Resistance; Larva; Rhodamine 123; Verapamil; Xenobiotics

1998
The in vivo effect of the administration of resistance-modulating agents on rhodamine 123 distribution in mice thymus and lymph nodes.
    Cancer letters, 1999, Mar-22, Volume: 137, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Drug Resistance, Neoplasm; Female; Fluorescent Dyes; Immunosuppressive Agents; Lymph Nodes; Mice; Rhodamine 123; Thymus Gland

1999
Anti-psychotic drugs reverse multidrug resistance of tumor cell lines and human AML cells ex-vivo.
    Cancer letters, 1999, May-03, Volume: 139, Issue:1

    Topics: Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Drug Interactions; Drug Resistance, Multiple; Enzyme Inhibitors; Humans; Leukemia, Myeloid; Rhodamine 123; Tumor Cells, Cultured

1999
Identification of a multidrug resistance-like system in Tetrahymena pyriformis: evidence for a new detoxication mechanism in freshwater ciliates.
    FEBS letters, 1999, Aug-13, Volume: 456, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies; ATP Binding Cassette Transporter, Subfamily B; Benz(a)Anthracenes; Blotting, Western; Cyclosporine; Doxorubicin; Drug Resistance, Multiple; Enzyme Inhibitors; Fresh Water; Immunohistochemistry; Inactivation, Metabolic; Rhodamine 123; Tetrahymena pyriformis

1999
Secretion of platelet-activating factor is mediated by MDR1 P-glycoprotein in cultured human mesangial cells.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10, Issue:11

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Cyclosporine; Glomerular Mesangium; Humans; Platelet Activating Factor; Rhodamine 123

1999
Inhibition of P-glycoprotein by D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS).
    Pharmaceutical research, 1999, Volume: 16, Issue:10

    Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Survival; Coloring Agents; Cyclosporine; Fluorouracil; Immunosuppressive Agents; Mice; Micelles; Paclitaxel; Polyethylene Glycols; Rhodamine 123; Vinblastine; Vitamin E

1999
Role of P-glycoprotein in ocular clearance of rhodamine 123 in rabbits.
    Pharmaceutical research, 2000, Volume: 17, Issue:4

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Eye; Male; Rabbits; Rhodamine 123

2000
Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure.
    European journal of pharmacology, 2000, Oct-20, Volume: 406, Issue:3

    Topics: Acute Kidney Injury; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Brain Chemistry; Caco-2 Cells; Cyclosporine; Glycerol; Humans; Kidney; Liver; Male; Metabolic Clearance Rate; Rats; Rats, Wistar; Rhodamine 123

2000
Specificity of doxorubicin versus rhodamine-123 in assessing P-glycoprotein functionality in the LLC-PK1, LLC-PK1:MDR1 and Caco-2 cell lines.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2000, Volume: 11, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cell Line; Cell Polarity; Cimetidine; Cyclosporine; Doxorubicin; Drug Resistance, Multiple; Epithelial Cells; Humans; Kinetics; LLC-PK1 Cells; Rhodamine 123; Swine; Tumor Cells, Cultured; Verapamil

2000
Mitochondrial permeability transition is a central coordinating event in N-(4-hydroxyphenyl)retinamide-induced apoptosis.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2000, Volume: 9, Issue:12

    Topics: Anticarcinogenic Agents; Apoptosis; Ascorbic Acid; Carcinoma, Squamous Cell; Cell Division; Cyclosporine; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fenretinide; Fluoresceins; Fluorescent Dyes; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Oxidation-Reduction; Permeability; Reactive Oxygen Species; Rhodamine 123; Skin Neoplasms; Tumor Cells, Cultured

2000
Pharmacokinetic interaction of cytochrome P450 3A-related compounds with rhodamine 123, a P-glycoprotein substrate, in rats pretreated with dexamethasone.
    Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biliary Tract; Blotting, Western; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Erythromycin; Intestinal Absorption; Intestines; Liver; Male; Midazolam; Oxidoreductases, N-Demethylating; Rats; Rats, Wistar; Rhodamine 123; Substrate Specificity; Verapamil

2001
Regulation of cyclosporin A sensitive mitochondrial permeability transition by the redox state of pyridine nucleotides.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2001, Volume: 128, Issue:1

    Topics: Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Chromatography, High Pressure Liquid; Cyclosporine; Enzyme Inhibitors; Fluorescent Dyes; Guinea Pigs; Hydrolysis; Ionophores; Light; Membrane Potentials; Mitochondria, Liver; Models, Chemical; NAD; NADP; Oxidation-Reduction; Oxidative Stress; Permeability; Pyridines; Rhodamine 123; Scattering, Radiation; Spectrometry, Fluorescence; tert-Butylhydroperoxide; Time Factors

2001
Apoptosis and adaptive responses to oxidative stress in human endothelial cells exposed to cyclosporin A correlate with BCL-2 expression levels.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:3

    Topics: Apoptosis; Benzopyrans; Cell Division; Cell Size; Cells, Cultured; Cyclin D1; Cyclosporine; DNA Fragmentation; Endothelium, Vascular; Fluorescent Dyes; Humans; Immunosuppressive Agents; Microscopy, Confocal; Oxidative Stress; Reactive Oxygen Species; Rhodamine 123

2001
P-glycoprotein efflux pump expression and activity in Calu-3 cells.
    Journal of pharmaceutical sciences, 2001, Volume: 90, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Caco-2 Cells; Cell Line; Cyclosporine; Enzyme Inhibitors; Fluorescent Dyes; Humans; Multidrug Resistance-Associated Proteins; Paclitaxel; Rhodamine 123; Vinblastine

2001
A human lymphocyte based ex vivo assay to study the effect of drugs on P-glycoprotein (P-gp) function.
    Pharmaceutical research, 2001, Volume: 18, Issue:1

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Separation; Cyclosporine; Enzyme Inhibitors; Fluorescent Dyes; Humans; Immunosuppressive Agents; Lymphocytes; Quinidine; Rhodamine 123; Tacrolimus; Verapamil

2001
Effect of P-glycoprotein modulators on the human extraneuronal monoamine transporter.
    European journal of pharmacology, 2001, Jun-22, Volume: 422, Issue:1-3

    Topics: 1-Methyl-4-phenylpyridinium; Arginine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Cations; Cell Line; Cyclosporine; Daunorubicin; Dose-Response Relationship, Drug; Histidine; Humans; Organic Cation Transport Proteins; Rhodamine 123; Time Factors; Tritium; Tyramine; Verapamil; Vinblastine

2001
Effect of chronic renal failure on the expression and function of rat intestinal P-glycoprotein in drug excretion.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:8

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Creatinine; Cyclosporine; Intestinal Mucosa; Jejunum; Kidney Failure, Chronic; Male; Mannitol; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley; Rhodamine 123; RNA, Messenger; Verapamil

2001
Inhibitors of mdr1-dependent transport activity delay accumulation of the mdr1 substrate rhodamine 123 in primary rat hepatocyte cultures.
    Toxicology, 2001, Oct-05, Volume: 167, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cyclosporine; Enzyme Inhibitors; Excipients; Fluorescent Dyes; Hepatocytes; Male; Octoxynol; Rats; Rats, Wistar; Rhodamine 123; Vanadates; Verapamil

2001
Intracellular levels of two cyclosporin derivatives valspodar (PSC 833) and cyclosporin a closely associated with multidrug resistance-modulating activity in sublines of human colorectal adenocarcinoma HCT-15.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:10

    Topics: Adenocarcinoma; Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Division; Colorectal Neoplasms; Cyclosporine; Cyclosporins; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Inhibitory Concentration 50; Intracellular Fluid; Rhodamine 123; Tumor Cells, Cultured; Verapamil

2001
Transport activity and surface expression of the Na+-Ca2+ exchanger NCX1 are inhibited by the immunosuppressive agent cyclosporin A and by the nonimmunosuppressive agent PSC833.
    The Journal of biological chemistry, 2002, Jan-25, Volume: 277, Issue:4

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Calcium; Cell Line; Cell Separation; Coloring Agents; Cyclosporine; Cyclosporins; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Flow Cytometry; HeLa Cells; Humans; Immunosuppressive Agents; Mutation; Myocardium; Protein Binding; Protein Transport; Rats; Rhodamine 123; Sodium-Calcium Exchanger; Spectrometry, Fluorescence; Transfection

2002
Expression of the human multidrug resistance gene mdr1 in leukemic cells and its application in studying P-glycoprotein antagonists.
    Chinese medical journal, 2000, Volume: 113, Issue:3

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Genes, MDR; Humans; K562 Cells; Leukemia; Retroviridae; Rhodamine 123; Transfection; Vincristine

2000
The inhibition of calcium signaling in T lymphocytes from old mice results from enhanced activation of the mitochondrial permeability transition pore.
    Mechanisms of ageing and development, 2002, Mar-31, Volume: 123, Issue:6

    Topics: Aging; Animals; Calcium; Calcium Signaling; Cells, Cultured; Cyclosporine; Female; Flavin-Adenine Dinucleotide; Fluorescent Dyes; Immunologic Memory; Intracellular Membranes; Ion Channels; Ionomycin; Ionophores; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidation-Reduction; Rhodamine 123; Spleen; Superoxides; T-Lymphocytes

2002
Effects of P-glycoprotein inhibitors on cadmium accumulation in cultured renal epithelial cells, LLC-PK1, and OK.
    Toxicology and applied pharmacology, 2002, Dec-15, Volume: 185, Issue:3

    Topics: Animals; Antibodies, Blocking; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cadmium; Cadmium Radioisotopes; Calcium Channel Blockers; Cyclosporine; Epithelial Cells; Fluorescent Dyes; Kidney; LLC-PK1 Cells; Protein Biosynthesis; Rats; Rhodamine 123; Swine; Vinblastine

2002
Molecular evidence and functional expression of P-glycoprotein (MDR1) in human and rabbit cornea and corneal epithelial cell lines.
    Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:7

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cell Line; Cornea; Cyclosporine; Dose-Response Relationship, Drug; Epithelium, Corneal; Gene Expression; Humans; Male; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; RNA, Messenger; Testosterone

2003
Measurement of basal, substrate induced and total P-glycoprotein activity in bronchoalveolar lavage T-cell subsets.
    Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2004, Volume: 57, Issue:2

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclosporine; Flow Cytometry; Fluorescence; Humans; Leukocytes, Mononuclear; Rhodamine 123; T-Lymphocyte Subsets

2004
Mitotracker green is a P-glycoprotein substrate.
    Bioscience reports, 2003, Volume: 23, Issue:4

    Topics: Aldehydes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Size; Cyclosporine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescence; Fluorescent Dyes; Humans; K562 Cells; Mitochondria; Rhodamine 123; Time Factors; Trifluoperazine; Verapamil

2003
Implication of mitochondrial involvement in apoptotic activity of fragile histidine triad gene: application of synchronous luminescence spectroscopy.
    Biopolymers, 2004, Volume: 73, Issue:4

    Topics: Acid Anhydride Hydrolases; Apoptosis; Carcinoma; Cell Division; Cell Line, Tumor; Chromosomes, Human, Pair 3; Cyclosporine; Cytochromes c; Cytoplasm; Enzyme Inhibitors; Fluorescent Dyes; Genes, Tumor Suppressor; Humans; Luminescent Measurements; Membrane Potentials; Mitochondria; Neoplasm Proteins; Rhodamine 123; Spectrum Analysis; Stomach Neoplasms; Time Factors

2004
Evaluation and comparison of MRP1 activity with three fluorescent dyes and three modulators in leukemic cell lines.
    Leukemia research, 2004, Volume: 28, Issue:6

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Bronchodilator Agents; Cyclosporine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Leukemia; Multidrug Resistance-Associated Proteins; Probenecid; Propionates; Quinolines; Rhodamine 123; Tumor Cells, Cultured

2004
Avermectins inhibit multidrug resistance of tumor cells.
    European journal of pharmacology, 2004, Jun-16, Volume: 493, Issue:1-3

    Topics: Animals; Cell Division; Cell Line, Tumor; Cell Survival; Cyclosporine; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Synergism; Fluoresceins; Fluorescence; Humans; Ivermectin; Leukemia P388; Male; Mice; Paclitaxel; Rhodamine 123; Russia; Vincristine

2004
Nitric oxide mediates cyclosporine-induced impairment of the blood-brain barrier in cocultures of mouse brain endothelial cells and rat astrocytes.
    European journal of pharmacology, 2004, Nov-28, Volume: 505, Issue:1-3

    Topics: Animals; Animals, Newborn; Astrocytes; ATP Binding Cassette Transporter, Subfamily B; Blood-Brain Barrier; Brain; Cell Line, Transformed; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Coculture Techniques; Cyclosporine; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Fluorescein; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Rhodamine 123

2004
Effect of p-glycoprotein inhibitor combinations on drug efflux from rat brain microvessel endothelial cells.
    Die Pharmazie, 2004, Volume: 59, Issue:12

    Topics: Adenosine Triphosphatases; Alkaloids; Animals; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzylisoquinolines; Blood-Brain Barrier; Calcium Channel Blockers; Capillaries; Cerebrovascular Circulation; Cyclosporine; Doxorubicin; Drug Synergism; Endothelial Cells; Fluorescent Dyes; Immunosuppressive Agents; Pharmaceutical Preparations; Rats; Rhodamine 123; Verapamil

2004
Comparative study on the effects of cyclosporin a in renal cells in culture.
    Nephron. Experimental nephrology, 2005, Volume: 99, Issue:3

    Topics: Aldehydes; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Cell Survival; Cyclosporine; Dogs; Flow Cytometry; Fluorescent Dyes; Immunosuppressive Agents; Kidney; LLC-PK1 Cells; Macaca mulatta; Rhodamine 123; Swine

2005
Biphasic accumulation kinetics of [99mTc]-hexakis-2-methoxyisobutyl isonitrile in tumour cells and its modulation by lipophilic P-glycoprotein ligands.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2005, Volume: 25, Issue:2-3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cricetinae; Cyclosporine; Drug Resistance, Multiple; Fluorine Radioisotopes; Gluconates; Humans; Intracellular Membranes; Ligands; Membrane Fluidity; Membrane Potentials; Mice; Mitochondria; Permeability; Rhodamine 123; Technetium Tc 99m Sestamibi; Verapamil

2005
Transport characteristics of rutin deca (H-) sulfonate sodium across Caco-2 cell monolayers.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:10

    Topics: Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Cyclosporine; Drug Interactions; Flavones; Humans; Hydrogen-Ion Concentration; Models, Biological; Rhodamine 123; Rutin; Temperature; Verapamil

2005
JC-1, a sensitive probe for a simultaneous detection of P-glycoprotein activity and apoptosis in leukemic cells.
    Cytometry. Part B, Clinical cytometry, 2006, Volume: 70, Issue:3

    Topics: Acute Disease; Annexin A5; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Carbocyanines; Cell Line, Tumor; Cyclosporine; Cytoplasm; Flow Cytometry; Fluorescent Dyes; Humans; Leukemia, Myeloid; Mitochondria; Propidium; Rhodamine 123; Staining and Labeling; Tumor Cells, Cultured

2006
Ginger significantly decreased the oral bioavailability of cyclosporine in rats.
    The American journal of Chinese medicine, 2006, Volume: 34, Issue:5

    Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Biological Transport; Cyclosporine; Drug Interactions; Ileum; Immunosuppressive Agents; In Vitro Techniques; Intestinal Absorption; Jejunum; Male; Metabolic Clearance Rate; Plant Extracts; Plant Roots; Random Allocation; Rats; Rats, Sprague-Dawley; Rhodamine 123; Zingiber officinale

2006
A "silent" polymorphism in the MDR1 gene changes substrate specificity.
    Science (New York, N.Y.), 2007, Jan-26, Volume: 315, Issue:5811

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Cell Membrane; Chlorocebus aethiops; Codon; Cyclosporine; Genes, MDR; Haplotypes; HeLa Cells; Humans; Mutagenesis, Site-Directed; Polymorphism, Single Nucleotide; Protein Biosynthesis; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; RNA, Messenger; Sirolimus; Substrate Specificity; Transfection; Verapamil

2007
Adaptive response to increased bile acids: induction of MDR1 gene expression and P-glycoprotein activity in renal epithelial cells.
    Pflugers Archiv : European journal of physiology, 2007, Volume: 454, Issue:4

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile Acids and Salts; Cell Line; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholic Acid; Cyclosporine; Deoxycholic Acid; Dogs; Enzyme Inhibitors; Epithelial Cells; Gastrointestinal Agents; Gene Expression Regulation; Kidney; Paclitaxel; Rhodamine 123; Taurocholic Acid

2007
Modification of multidrug resistance of tumor cells by ionizing radiation.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Cell Count; Cell Line, Tumor; Combined Modality Therapy; Cyclosporine; Daunorubicin; Dose-Response Relationship, Radiation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Laryngeal Neoplasms; Paclitaxel; Radiation, Ionizing; Reactive Oxygen Species; Rhodamine 123; Time Factors; Vincristine

2008
Expression of ABC-transporters in human corneal tissue and the transformed cell line, HCE-T.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2007, Volume: 23, Issue:2

    Topics: Analysis of Variance; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Cell Line; Cornea; Cyclosporine; Epithelium, Corneal; Gene Expression Profiling; Humans; Microscopy; Models, Biological; Permeability; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; RNA, Messenger

2007
Assessment of antiepileptic drugs as substrates for canine P-glycoprotein.
    American journal of veterinary research, 2007, Volume: 68, Issue:10

    Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; Blood-Brain Barrier; Cell Line, Tumor; Cyclosporine; Dogs; Flow Cytometry; Immunoblotting; Ivermectin; Osteosarcoma; Rhodamine 123; Substrate Specificity

2007
Inhibition of multidrug resistance by adamantylgb3, a globotriaosylceramide analog.
    The Journal of biological chemistry, 2008, Feb-22, Volume: 283, Issue:8

    Topics: Adamantane; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Calcium Channel Blockers; Cell Membrane; Cell Polarity; Cyclosporine; Dogs; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Endocytosis; Enzyme Inhibitors; Fluorescent Dyes; Golgi Apparatus; Humans; Intestinal Mucosa; Neoplasms; Protein Binding; Protein Structure, Secondary; Protein Synthesis Inhibitors; Protein Transport; Rhodamine 123; Shiga Toxins; Time Factors; Trihexosylceramides; Up-Regulation; Verapamil; Vinblastine

2008
Repetitive/temporal hypoxia increased P-glycoprotein expression in cultured rat brain microvascular endothelial cells in vitro.
    Neuroscience letters, 2008, Feb-27, Volume: 432, Issue:3

    Topics: Animals; Animals, Newborn; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Cell Survival; Cells, Cultured; Cyclosporine; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation; Hypoxia; Rats; Rats, Sprague-Dawley; Rhodamine 123; Sincalide; Time Factors

2008
Increased P-glycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro.
    Neuroscience letters, 2008, Apr-04, Volume: 434, Issue:3

    Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbamazepine; Cells, Cultured; Cerebral Arteries; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelial Cells; Immunosuppressive Agents; Indicators and Reagents; Microcirculation; Phenobarbital; Phenytoin; Rats; Rhodamine 123; Sodium Channel Blockers; Time; Up-Regulation; Valproic Acid; Verapamil

2008
Effect of some P-glycoprotein modulators on Rhodamine-123 absorption in guinea-pig ileum.
    Bioorganic & medicinal chemistry letters, 2008, Jul-01, Volume: 18, Issue:13

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Chemistry, Pharmaceutical; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Resistance, Multiple; Guinea Pigs; Humans; Ileum; Models, Chemical; Rhodamine 123; Tamoxifen; Verapamil

2008
Development and characterisation of a new model of rat trophoblasts.
    Toxicology in vitro : an international journal published in association with BIBRA, 2009, Volume: 23, Issue:1

    Topics: Animal Testing Alternatives; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Proliferation; Cell Survival; Cryopreservation; Cyclosporine; Cyclosporins; Drug Evaluation, Preclinical; Female; Fluoresceins; Fluorescent Dyes; Neoplasm Proteins; Organ Culture Techniques; Pregnancy; Rats; Rats, Wistar; Rhodamine 123; Trophoblasts

2009
A comparison of Zn2+- and Ca2+-triggered depolarization of liver mitochondria reveals no evidence of Zn2+-induced permeability transition.
    Cell calcium, 2009, Volume: 45, Issue:5

    Topics: Animals; Calcium; Cation Transport Proteins; Cyclosporine; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Permeability; Rats; Rats, Sprague-Dawley; Rhodamine 123; Ruthenium Red; Zinc

2009
Effects of P-glycoprotein and Mrp2 inhibitors on the hepatobiliary disposition of Rhodamine 123 and its glucuronidated metabolite in isolated perfused rat livers.
    Journal of pharmaceutical sciences, 2010, Volume: 99, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biliary Tract; Chromatography, High Pressure Liquid; Cyclosporine; Dose-Response Relationship, Drug; Fluorescent Dyes; Glucuronides; In Vitro Techniques; Liver; Male; Microsomes, Liver; Perfusion; Rats; Rats, Sprague-Dawley; Rhodamine 123; Sulfobromophthalein; Time Factors; Tissue Distribution

2010
Effect of cyclosporine on drug transport and pharmacokinetics of nifedipine.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2009, Volume: 63, Issue:9

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cyclosporine; Drug Interactions; Male; Nifedipine; Rats; Rats, Wistar; Rhodamine 123

2009
Effects of intestinal ischemia/reperfusion on P-glycoprotein mediated biliary and renal excretion of rhodamine123 in rat.
    Drug metabolism and pharmacokinetics, 2009, Volume: 24, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biliary Tract; Cimetidine; Cyclosporine; Kidney; Liver; Male; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Reperfusion Injury; Rhodamine 123; Tetraethylammonium; Verapamil

2009
Interaction of Rhei Rhizoma extract with cytochrome P450 3A and efflux transporters in rats.
    Die Pharmazie, 2010, Volume: 65, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Carrier Proteins; Cyclosporine; Cytochrome P-450 CYP3A; Dinitrochlorobenzene; GABA Modulators; Glutathione; Immunosuppressive Agents; Indicators and Reagents; Intestinal Mucosa; Intestines; Liver; Male; Microsomes, Liver; Midazolam; Plant Extracts; Rats; Rats, Sprague-Dawley; Rheum; Rhodamine 123

2010
Iodination increases the activity of verapamil derivatives in reversing PGP multidrug resistance.
    Anticancer research, 2010, Volume: 30, Issue:7

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Cycle; Cyclosporine; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Humans; K562 Cells; Male; Myocytes, Cardiac; Rats; Rats, Wistar; Rhodamine 123; Verapamil

2010
Pgp inhibition by UIC2 antibody can be followed in vitro by using tumor-diagnostic radiotracers, 99mTc-MIBI and 18FDG.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2010, Dec-23, Volume: 41, Issue:5

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Female; Fluorodeoxyglucose F18; Glucose; Humans; Ovarian Neoplasms; Paclitaxel; Protein Binding; Rhodamine 123; Technetium Tc 99m Sestamibi; Tumor Cells, Cultured

2010
Reversion of resistance to immunosuppressive agents in three patients with psoriatic arthritis by cyclosporine A: modulation of P-glycoprotein function.
    Clinical immunology (Orlando, Fla.), 2011, Volume: 138, Issue:1

    Topics: Adult; Arthritis, Psoriatic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Sedimentation; C-Reactive Protein; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclosporine; Drug Resistance; Female; Humans; Immunosuppressive Agents; Joints; Male; Methotrexate; Middle Aged; Rhodamine 123; Sulfasalazine; T-Lymphocytes; Treatment Outcome; Verapamil

2011
Using rhodamine 123 accumulation in CD8 cells as a surrogate indicator to study the P-glycoprotein modulating effect of cepharanthine hydrochloride in vivo.
    Journal of biomedicine & biotechnology, 2011, Volume: 2011

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzylisoquinolines; Carcinoma, Hepatocellular; CD8-Positive T-Lymphocytes; Cyclosporine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorescent Dyes; Fluorouracil; Humans; Indicators and Reagents; Liver Neoplasms; Mice; Rhodamine 123; Tumor Cells, Cultured; Verapamil; Xenograft Model Antitumor Assays

2011
Uptake characteristics of pinocembrin and its effect on p-glycoprotein at the blood-brain barrier in in vitro cell experiments.
    Journal of Asian natural products research, 2012, Volume: 14, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Cyclosporine; Dose-Response Relationship, Drug; Flavanones; Neuroprotective Agents; Rats; Rhodamine 123; Verapamil

2012
Etoposide modulates the effects of oral morphine analgesia by targeting the intestinal P-glycoprotein.
    The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:4

    Topics: Administration, Oral; Analgesics, Opioid; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cyclosporine; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Etoposide; Intestinal Mucosa; Male; Mice; Morphine; Pain; Rhodamine 123; Up-Regulation

2012
[Evaluation of P-glycoprotein mediated in vitro loperamide biliary excretion with sandwich-cultured rat hepatocytes model].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:4

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biliary Tract; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclosporine; Hepatocytes; Loperamide; Male; Quinidine; Quinolines; Rats; Rats, Sprague-Dawley; Rhodamine 123; Tandem Mass Spectrometry

2012
Impact of small molecules immunosuppressants on P-glycoprotein activity and T-cell function.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2012, Volume: 15, Issue:3

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Cyclosporine; Cytokines; Humans; Immunosuppressive Agents; Rhodamine 123; Sirolimus; T-Lymphocyte Subsets; Tacrolimus

2012
Mitochondrial localization of P-glycoprotein and peptide transporters in corneal epithelial cells--novel strategies for intracellular drug targeting.
    Experimental eye research, 2013, Volume: 106

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Blotting, Western; Carbocyanines; Cells, Cultured; Cyclosporine; Dipeptides; Drug Delivery Systems; Epithelium, Corneal; Flow Cytometry; Fluorescent Dyes; Membrane Potential, Mitochondrial; Microscopy, Confocal; Microscopy, Electron, Transmission; Mitochondria; Peptide Transporter 1; Quinidine; Rabbits; Rhodamine 123; Symporters

2013
Functional characterization of hepatic transporters using intravital microscopy.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Aug-16, Volume: 49, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Cyclosporine; Fluorescein; Fluorescent Dyes; Liver; Male; Microscopy, Fluorescence, Multiphoton; Models, Biological; Organic Anion Transporters; Rats; Rats, Wistar; Rhodamine 123; Rifampin

2013
Resveratrol and P-glycoprotein inhibitors enhance the anti-skin cancer effects of ursolic acid.
    Molecular cancer research : MCR, 2013, Volume: 11, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Cell Survival; Cyclosporine; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Mice; Resveratrol; Rhodamine 123; Skin Neoplasms; Stilbenes; Triterpenes; Ursolic Acid; Verapamil

2013
Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Sep-09, Volume: 111, Issue:36

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Brain; Chlorocebus aethiops; Cholinesterase Inhibitors; Cognition; COS Cells; Cyclosporine; Drug Design; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Kinetics; Ligands; Mice; Permeability; Piperidines; Receptors, Serotonin, 5-HT4; Rhodamine 123; Serotonin 5-HT4 Receptor Agonists; Solubility; Task Performance and Analysis

2014
Trantinterol, a novel β2-adrenoceptor agonist, noncompetitively inhibits P-glycoprotein function in vitro and in vivo.
    Molecular pharmaceutics, 2015, Jan-05, Volume: 12, Issue:1

    Topics: Adenosine Triphosphatases; Adrenergic beta-Agonists; Animals; Antibodies, Monoclonal; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport; Caco-2 Cells; Clenbuterol; Cyclosporine; Digoxin; Dogs; Drug Evaluation, Preclinical; Humans; Madin Darby Canine Kidney Cells; Male; Paclitaxel; Rats; Rats, Wistar; Rhodamine 123

2015
Possible involvement of cationic-drug sensitive transport systems in the blood-to-brain influx and brain-to-blood efflux of amantadine across the blood-brain barrier.
    Biopharmaceutics & drug disposition, 2015, Volume: 36, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Amantadine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Brain; Cell Line; Cyclosporine; Ion Pumps; Male; Microinjections; Quinidine; Rats; Rhodamine 123; Tritium; Verapamil

2015
2'[(18)F]-fluoroethylrhodamine B is a promising radiotracer to measure P-glycoprotein function.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2015, Jul-10, Volume: 74

    Topics: Absorption, Physiological; Animals; ATP Binding Cassette Transporter, Subfamily B; Carcinoma; Cell Line, Tumor; Cyclosporine; Drug Resistance, Neoplasm; Female; Fluorescent Dyes; Fluorine Radioisotopes; Humans; Immunosuppressive Agents; Membrane Potential, Mitochondrial; Mice; Neoplasm Proteins; NIH 3T3 Cells; Ovarian Neoplasms; Proton Ionophores; Radioactive Tracers; Recombinant Proteins; Rhodamine 123; Rhodamines; Uterine Cervical Neoplasms

2015
Rat precision-cut intestinal slices to study P-gp activity and the potency of its inhibitors ex vivo.
    Toxicology in vitro : an international journal published in association with BIBRA, 2015, Volume: 29, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cyclosporins; In Vitro Techniques; Intestinal Mucosa; Isoquinolines; Ketoconazole; Male; Quinazolines; Quinidine; Rats, Wistar; Rhodamine 123; Verapamil

2015
ATP Binding Cassette Transporter Mediates Both Heme and Pesticide Detoxification in Tick Midgut Cells.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Acaricides; Adenosine Triphosphate; Animals; Antibodies; Arthropod Proteins; ATP-Binding Cassette Transporters; Cattle; Chromatography, High Pressure Liquid; Cyclosporine; Female; Heme; Intestines; Metalloporphyrins; Protein Binding; Protein Structure, Tertiary; Protoporphyrins; Rhipicephalus; Rhodamine 123; RNA Interference; Tick Infestations; Toluidines

2015
Effects of MDR1 1236C > T-2677G > T-3435C > T polymorphisms on the intracellular accumulation of tacrolimus, cyclosporine A, sirolimus and everolimus.
    Xenobiotica; the fate of foreign compounds in biological systems, 2019, Volume: 49, Issue:11

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Drug Resistance; Everolimus; Humans; Immunosuppressive Agents; LLC-PK1 Cells; Polymorphism, Single Nucleotide; Recombinant Proteins; Rhodamine 123; Sirolimus; Swine; Tacrolimus

2019
Dielectrophoretic trapping of single leukemic cells using the conventional and compact optical measurement systems.
    Electrophoresis, 2019, Volume: 40, Issue:10

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Separation; Cell Shape; Cyclosporine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Electrophoresis; Equipment Design; Fluorescence; Fluorescent Dyes; Humans; Lab-On-A-Chip Devices; Leukemia, Myeloid, Acute; Microscopy, Fluorescence; Rhodamine 123; Single-Cell Analysis

2019
Low-dose Pimecrolimus, an FDA-approved Calcineurin Inhibitor, Sensitizes Drug-resistant Cancer Cells
    Anticancer research, 2023, Volume: 43, Issue:3

    Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcineurin Inhibitors; Cyclosporine; Humans; Neoplasms; Rhodamine 123; Tacrolimus

2023
Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein.
    Molecular pharmacology, 2000, Volume: 57, Issue:1

    Topics: Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Humans; Karyotyping; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Sequence Homology, Amino Acid

2000
Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells.
    Biochemical and biophysical research communications, 2001, Jul-06, Volume: 285, Issue:1

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Membrane; Cloning, Molecular; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasm Proteins; Recombinant Proteins; Spodoptera; Tumor Cells, Cultured

2001
Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites.
    Pharmaceutical research, 2003, Volume: 20, Issue:4

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport, Active; Biomarkers; Cells, Cultured; Drug Interactions; Fluorescent Dyes; Humans

2003
New functional assay of P-glycoprotein activity using Hoechst 33342.
    Bioorganic & medicinal chemistry, 2007, Dec-01, Volume: 15, Issue:23

    Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fluoresceins; Humans; Microscopy, Fluorescence; Molecular Structure; Principal Component Analysis; Time Factors

2007